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Journal articles on the topic "E.B. Moore and Co"
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BURGIN, K. "Realities in childbearing, second edition By Mary Lou Moore, , and Ora Strickland, . Philadelphia: W. B. Saunders Co., 1983. 1126 pages. $29.50, hardcover." Journal of Nurse-Midwifery 30, no. 2 (March 1985): 129. http://dx.doi.org/10.1016/0091-2182(85)90129-6.
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KITLV, Redactie. "Book Reviews." New West Indian Guide / Nieuwe West-Indische Gids 62, no. 1-2 (January 1, 1988): 51–101. http://dx.doi.org/10.1163/13822373-90002046.
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-Brenda Plummer, Carol S. Holzberg, Minorities and power in a black society: the Jewish community of Jamaica. Maryland: The North-South Publishing Company, Inc., 1987. xxx + 259 pp.-Scott Guggenheim, Nina S. de Friedemann ,De sol a sol: genesis, transformacion, y presencia de los negros en Colombia. Bogota: Planeta Columbiana Editorial, 1986. 47 1pp., Jaime Arocha (eds)-Brian L. Moore, Mary Noel Menezes, Scenes from the history of the Portuguese in Guyana. London: Sister M.N. Menezes, RSM, 1986. vii + 175 PP.-Charles Rutheiser, Brian L. Moore, Race, power, and social segmentation in colonial society: Guyana after slavery 1838-1891. New York; Gordon and Breach, 1987. 310 pp.-Thomas Fiehrer, Virginia R. Dominguez, White by definition: social classification in Creole Louisiana. Rutgers, New Jersey: Rutgers University Press, 1986. xviii + 325 pp.-Kenneth Lunn, Brian D. Jacobs, Black politics and urban crisis in Britain. Cambridge, London, New Rochelle, Melbourne and Sydney: Cambridge University Press, 1986. vii + 227 pp.-Brian D. Jacobs, Kenneth Lunn, Race and labour in twentieth-cenruty Britain, London: Frank Cass and Co. Ltd., 1985. 186 pp.-Kenneth M. Bilby, Dick Hebdige, Cut 'n' mix: culture, identity and Caribbean Music. New York: Metheun and Co. Ltd, 1987. 177 pp.-Riva Berleant-Schiller, Robert Dirks, The black saturnalia: conflict and its ritual expression on British West Indian slave plantations. Gainesville, Fl.: University of Florida Press, Monographs in Social Sciences No. 72. xvii + 228.-Marilyn Silverman, James Howe, The Kuna gathering: contemporary village politics in Panama. Austin, Texas: University of Texas Press, 1986. xvi + 326 pp.-Paget Henry, Evelyne Huber Stephens ,Democratic socialism in Jamaica: the political movement and social transformation in dependent capitalism. Princeton, N.J.: Princeton University Press, 1985. xx + 423 pp., John D. Stephens (eds)-Bridget Brereton, Scott B. Macdonald, Trinidad and Tobago: democracy and development in the Caribbean. New York, Connecticut, London: Praeger Publishers, 1986. ix + 213 pp.-Brian L. Moore, Kempe Ronald Hope, Guyana: politics and development in an emergent socialist state. Oakville, New York, London: Mosaic Press, 1985, 136 pp.-Roland I. Perusse, Richard J. Bloomfield, Puerto Rico: the search for a national policy. Boulder and London: Westview Press, Westview Special Studies on Latin America and the Caribbean, 1985. x + 192 pp.-Charles Gilman, Manfred Gorlach ,Focus on the Caribbean. 1986. Amsterdam/Philadelphia, John Benjamins., John A. Holm (eds)-Viranjini Munasinghe, EPICA, The Caribbean: survival, struggle and sovereignty. Washington, EPICA (Ecumenical Program for Interamerican Communication and Action), 1985.-B.W. Higman, Sidney W. Mintz, Sweetness and power: the place of sugar in modern history. New York: Elisabeth Sifton Books, Viking Penguin Inc., 1985. xxx + 274 pp.
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Thadhani, N. N. "Review of: “ CHEMICAL METALLURGY ” by J.J. Moore Co-authors: E.A. Boyce, MJ. Brooks, B. Perry, P.J. Sheridan Butterworths and Co. (Publishers) London, Second Edition, 435 pages, hard cover, 1990." Materials and Manufacturing Processes 7, no. 4 (January 1992): 671–73. http://dx.doi.org/10.1080/10426919208947449.
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Horrocks, M. "Endovascular surgery. W. S. Moore and S. S. Ahn, eds. 190 × 266 mm. Pp. 550. Illustrated. 1989. London: W. B. Saunders and Co. £64.00 hardhack." British Journal of Surgery 77, no. 10 (October 1990): 1197. http://dx.doi.org/10.1002/bjs.1800771049.
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Pautler, Paul A. "BOOK REVIEW: CURB RIGHTS: A FOUNDATION FOR FREE ENTERPRISE IN URBAN TRANSIT, by Klein, D. B., Moore, A. T. and Reja, B., Washington, DC: Brookings Institution Press, 1997, 148 pp." Managerial and Decision Economics 18, no. 4 (June 1997): 345–46. http://dx.doi.org/10.1002/(sici)1099-1468(199706)18:4<345::aid-mde830>3.0.co;2-k.
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Shrestha, D. B., P. Budhathoki, Y. R. Sedhai, L. B. Shrestha, S. Awal, B. Upadhaya Regmi, J. Yadav, R. Baniya, S. Thapaliya, and G. Dangal. "Prevalence of Hepatitis B and C among HIV Infected Patients in Nepal over 1990-2020." Kathmandu University Medical Journal 19, no. 1 (March 31, 2021): 132–39. http://dx.doi.org/10.3126/kumj.v19i1.49598.
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Background Hepatitis B and C (HBV and HCV) are viral infections caused by corresponding viruses. Here in this study we planned to conduct this meta-analysis to pool data on the prevalence and risk factors of HBV and/or HCV among HIV patients in Nepal.
Method We used MOOSE guideline for the systemic review of available literature. We searched online databases using appropriate keywords. We used CMA-3 for data synthesis. Odds ratio, and proportion were used to estimate the outcome with a 95% confidence interval where appropriate. We assessed the heterogeneity using the I-squared (I2) test.
Result We included nine studies for our synthesis. Pooling of data showed HBV in 4.6% (CI: 3.7-5.6), HCV in 19.7% (CI: 10.8-33.0), both HBV and HCV in 1.3% (CI: 0.5-3.7) in HIV affected individuals. Among HBV co-infected HIV positive patients, 59.5% (CI: 25.5-86.3) were male; 76.1% (CI: 30.1-96.0) were married and 43.6% (CI: 3.8-93.8) had a history of intravenous drug use (IVDU). Among HCV co-infected HIV positive individuals 88.3% (CI: 73.6-95.4) were male; 63.6% (CI: 55.4-71.1) were married; 91.5% (CI: 68.6-98.1) were literate; 59.2% (CI: 49.9-67.9) were on ART; and 92.2% (95%CI: 84.9-96.1) had a history of IVDU.
Conclusion The pooled prevalence of co-infection with HBV, HCV, and combined HBV and HCV were 4.6%, 19.7% and 1.3% respectively among HIV positive patients. Thus, it is necessary to appropriately screen for HBV and HCV in individuals diagnosed with HIV and high-risk populations. IVDU remains the most common risk factor found in co-infected individuals.
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Krishnan, Venkatesh, Ching-Wei Chang, Habib Hamidi, Michael A. Bookman, Charles Landen, Tashanna Myers, Hiroaki Kajiyama, et al. "Abstract 5702: Ovarian cancer tumor microenvironment and atezolizumab (atezo) clinical activity: IMagyn050 sub-study." Cancer Research 83, no. 7_Supplement (April 4, 2023): 5702. http://dx.doi.org/10.1158/1538-7445.am2023-5702.
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Abstract Background: Tumor biomarkers such as CD8 density and location (i.e., immune inflamed phenotype) and immune rich molecular subtype have been linked to immune checkpoint blockade (ICB) overall survival (OS) in different cancers. The IMagyn050 trial (NCT03038100), which evaluated the efficacy of Atezo vs placebo (Pla) with carboplatin, paclitaxel and bevacizumab (CPB) in front line ovarian cancer patient (pts), did not meet its co-primary endpoints of PFS in ITT or PD-L1+ (Moore et al. JCO 2021). In the current IMagyn050 substudy we assessed potential predictive tumor immune biomarkers for Atezo clinical benefit. Methods: FFPE tumors from the biomarker evaluable population were tested for PD-L1 IHC, CD8/PanCK IHC (total CD8 T cells and immune location phenotypes [inflamed, excluded, desert]) and RNA-seq (to derive molecular subtypes, biological pathways and cellular components [xCELL]) in tissue from baseline (n=860), on-treatment (OT, 9 weeks, n=233), intra- (n=8) and inter-lesion (n=12) matched samples. Hazard ratio (HR) interaction test from multivariate adjusted Cox-regression analysis for PFS and OS was performed to test predictive biomarkers. Results: While tumors with CD8 T cells, immunoreactive molecular subtypes or immune inflamed phenotype were enriched for PD-L1+, only pts with immune inflamed tumors showed improved OS Atezo benefit (HR 0.67). Improved Atezo PFS/OS benefit was also observed in pts with whose tumors had high oxidative phosphorylation (OXPHOS, HR: 0.72/0.65) and UV Response (UV, HR: 0.64/0.58) but not IFNγ response. Plasma B cells were linked to improved OS Atezo benefit vs Pla (HR 0.53). We leveraged OT samples from pts in the neoadjuvant cohort to assess treatment effect on the tumor microenvironment. Analyses showed that CPB reduced tumor proliferation and increased tumor immune inflammation (CD8 T cells, PD-L1 and IFNα/IFNγ response), further increased by Atezo. Immune inflammation is challenging in ovarian cancer due to extensive tumor heterogeneity. Prevalence of tumor biomarkers varied by anatomic locations: total CD8, CD8 localization and molecular subtypes. Inter- and intra-lesion biomarker status within the same pt showed PD-L1 and plasma B cells as most consistent. Molecular subtypes and immune phenotypes had moderate intra-lesion agreement but discordant between lesions. PD-L1 and OXPHOS were the only biomarkers linked to Atezo benefit regardless of anatomical location. Conclusion: This comprehensive exploratory study suggests that DNA damage, OXPHOS, plasma B cells and immune inflamed tumors, but not molecular subtypes or total CD8 T cells, may predict Atezo + CPB OS. This treatment promotes immune inflammation in OC tumors. Notably, we found that several biomarkers are highly heterogeneous. Our findings highlight the challenges of achieving durable clinical benefit from targeted immunotherapy in ovarian cancer pts. Citation Format: Venkatesh Krishnan, Ching-Wei Chang, Habib Hamidi, Michael A. Bookman, Charles Landen, Tashanna Myers, Hiroaki Kajiyama, Sakari Hietanen, Lyndsay Willmott, Premal Thaker, Cagatay Taskiran, Jalid Sehouli, Victor Khor, Yvonne Lin Liu, Sandro Pignata, Kathleen Moore, Luciana Molinero. Ovarian cancer tumor microenvironment and atezolizumab (atezo) clinical activity: IMagyn050 sub-study. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 5702.
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Morrison, James C., Kimlin T. Ashing, Gaole Song, Timethia J. Bonner, Che Ngufor, Getachew Dagne, Arnold Merriweather, et al. "Abstract 808: iCCaRE engagement of faith-based organizations to co-create and co-disseminate infographics addressing disparities in prostate cancer literacy and clinical and biospecimen studies." Cancer Research 84, no. 6_Supplement (March 22, 2024): 808. http://dx.doi.org/10.1158/1538-7445.am2024-808.
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Abstract Black men hold the highest prostate cancer burden among all ethnicities; thus, there is an urgent need for research to inform the development and implementation of a culturally tailored intervention to reduce disparities and improve outcomes. In response, the Inclusive Cancer Care Research Equity (iCCaRE) Consortium was created to advance health equity and reduce disparities in prostate cancer. Addressing the unique needs of Black men require a genuine bidirectional relationship between scientist and the community. In the Black community, faith-based organizations are respected institutions advocating for health equity and justice. Given their vital role as community health gatekeepers, the iCCaRE Consortium partners with faith-based organizations. Rooted in community engaged research (CER), we conducted an environmental scan through stakeholder meetings to discuss the prevailing challenges and opportunities to meet the needs of the Black community along the prostate cancer care continuum. iCCaRE investigators including Partnership Engagement Services (PES) core partnered with faith-based organizations to ensure and advance community responsive cancer prevention. Together, with our faith-based leaders (N=18), we identified gaps including issues associated with the care continuum from screening to diagnosis and from treatment to survivorship; disparities according to health coverage and social determinants of health, and best practices to assist patients including care coordination, patient navigation, digital innovations, and programs offered by patient advocacy organizations. In response to the needs of the community and the strengths of faith-based organization, we prioritized our initial focus on increasing community prostate cancer literacy and activation using co-design educational infographics for both traditional and technology-based communication platforms. The infographics provided evidence-based facts about prostate cancer burden in the Black community; and using a call to action approach, we emphasized the importance of taking action for life saving screening, prevention and healthy lifestyle. Taking action in prostate cancer symptom recognition, survivorship care, and quality care. Also, co-designed infographics were created for clinical studies and biospecimen awareness and participation and the importance of advocacy and equitable care. Another component incorporated face to face trainings and presentations to enhance their knowledge of cancer screening tools, epidemiology of prostate cancer, and pathways to care. This presentation highlighted the first step towards community based intervention development, implementation and dissemination towards equity and justice for prostate cancer prevention and patient/survivor improvements for Black men. Citation Format: James C. Morrison, Kimlin T. Ashing, Gaole Song, Timethia J. Bonner, Che Ngufor, Getachew Dagne, Arnold Merriweather, John McCall, Ewan Cobran, Cassandra N. Moore, Fornati Bedell, Rotimi Oladapo, Floyd B. Willis, Runcie Chidebe Chidebe, Noreen A. Stephenson, JoAnne S. Oliver, Vinessa Gordon, Folakemi Odedina. iCCaRE engagement of faith-based organizations to co-create and co-disseminate infographics addressing disparities in prostate cancer literacy and clinical and biospecimen studies [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 808.
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Moore, Colin Edward, and Elod L. Gyenge. "Tuning the Composition of Bimetallic Electrodeposited Sn-Pb Catalysts for Enhanced Activity and Durability in CO2 Electroreduction to Formate." ECS Meeting Abstracts MA2018-01, no. 31 (April 13, 2018): 1829. http://dx.doi.org/10.1149/ma2018-01/31/1829.
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Efficient and durable catalysts are needed to convert CO2 to value added products. In recent years, extensive research has been done on tin (Sn) because of its high faradaic efficiency for producing formate (HCOO-) from CO2 [1–5] and lead (Pb) because of its high hydrogen evolution (HER) overpotential [4, 6]. In our recent study [7], bimetallic Sn-Pb catalysts with five different Sn/Pb atomic ratios were electrodeposited on Teflonated carbon paper and non-Teflonated carbon cloth using both metal fluoroborate- and metal oxide-containing deposition media to produce catalysts for electrochemical reduction of CO2 (ERC) to HCOO-. The interaction between catalyst composition, morphology, substrate and deposition media was investigated by cyclic voltammetry followed by chronoamperometry at -2.0 V vs. Ag/AgCl for 2 h in 0.5 M KHCO3. Sn majority catalysts with 15 to 35 atomic % Pb generated faradaic efficiencies up to 95% with stable performance. Pure Sn catalysts on the other hand, in spite of high initial stage formate production rates, experienced extensive (up to 30%) decrease of the faradaic efficiency. The decrease in faradaic efficiency is most likely due to the reduction of the SnO2 layer to metallic Sn0 during formate production. This newly formed Sn0 surface is no longer active for CO2 reduction to formate but instead preferentially produces parasitic H2. XRD results demonstrated the presence of polycrystalline SnO2 after electrolysis using Sn-Pb catalysts with 35 atomic % Pb and its absence in case of pure Sn. It is proposed that the presence of Pb (15 to 35 at %) in Sn majority catalysts stabilized SnO2, which is responsible for the enhanced faradaic efficiency and catalytic durability in ERC. Our results point to a promising strategy for increasing the durability of Sn based catalyst materials for ERC. Oloman C, Li H (2008) Electrochemical Processing of Carbon Dioxide. ChemSusChem 1:385–391. doi: 10.1002/cssc.200800015 Li H, Oloman C (2005) The Electro-Reduction of Carbon Dioxide in a Continuous Reactor. J Appl Electrochem 35:955–965. doi: 10.1007/s10800-005-7173-4 Bumroongsakulsawat P, Kelsall GH (2015) Tinned graphite felt cathodes for scale-up of electrochemical reduction of aqueous CO2. Electrochimica Acta 159:242–251. doi: 10.1016/j.electacta.2015.01.209 Alvarez-Guerra M, Del Castillo A, Irabien A (2014) Continuous electrochemical reduction of carbon dioxide into formate using a tin cathode: Comparison with lead cathode. Chem Eng Res Des 92:692–701. doi: 10.1016/j.cherd.2013.11.002 Chen Y, Kanan MW (2012) Tin Oxide Dependence of the CO2 Reduction Efficiency on Tin Electrodes and Enhanced Activity for Tin/Tin Oxide Thin-Film Catalysts. J Am Chem Soc 134:1986–1989. doi: 10.1021/ja2108799 Innocent B, Liaigre D, Pasquier D, Ropital F, Léger J-M, Kokoh KB (2009) Electro-reduction of carbon dioxide to formate on lead electrode in aqueous medium. J Appl Electrochem 39:227–232. doi: 10.1007/s10800-008-9658-4 Gyenge EL, Moore CE (2017) Tuning the Composition of Bimetallic Electrodeposited Sn-Pb Catalysts for Enhanced Activity and Durability in CO2 Electroreduction to Formate. ChemSusChem 17:3512-3519 . doi: 10.1002/cssc.201700761 Figure 1. Cumulative formate production faradaic efficiency (FE) (a, c) and total moles of formate synthesized (b, d) for catalysts produced by electrodeposition using the fluoroborate bath. Chronoamperometry at -2.0 V vs Ag/AgCl in 0.5 M KHCO3 at 293 K for 2 hours. Substrates: (a, b) teflonated carbon paper and (c, d) carbon cloth. Figure 1
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Moore, Jay A., Andrew M. Evens, Justin Newberg, Eric A. Severson, Jennifer Mills, Jordan Carter, Rahul Matnani, Jo-Anne Vergilio, Sally E. Trabucco, and Shridar Ganesan. "Genomic Ancestry in B Cell Lymphoid Malignancies." Blood 136, Supplement 1 (November 5, 2020): 5–6. http://dx.doi.org/10.1182/blood-2020-137533.
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Introduction: B cell lymphoma/leukemias (BCL) are a diverse set of malignancies. The genomic landscape of many BCL subtypes have been described. However, genomic ancestry has rarely been investigated. We applied SNP-based genomic ancestry prediction to comprehensive genomic profiling (CGP) data to identify significant enrichment of ancestry by subtype. We also explored enrichment of genomic alterations (GAs) by ancestry. Methods: During routine clinical care, 2834 unique patient (pt) samples of BCLs underwent CGP for 406 DNA genes and 265 RNA genes to detect all classes of GAs on the FoundationOne® Heme platform. This dataset was enriched for relapsed/refractory pts as they are more likely to have genomic testing as part of clinical care (referral bias). Each pt was assigned an ancestry of American (AMR), African (AFR), East Asian (EAS), European (EUR), or South Asian (SAS) using a SNP-based machine learning methodology (J. Newberg et al., AACR 2019). AMR was defined using a mix of Hispanic and Latin American populations. Enrichment analyses were performed using Fisher's exact test with FDR correction. Results: We compared the ancestry composition of each BCL subtype to the overall ancestry composition of the rest of the sample set (Fig 1A). Pts of AFR ancestry were overrepresented in plasmablastic lymphoma (PBL) (OR=7.2, P<0.05); EAS pts were overrepresented in Burkitt lymphoma (BL) (OR=4.99, P<0.05); and AMR pts were overrepresented in acute B-cell lymphoblastic leukemia/lymphoma (B-ALL) (OR=3.2, P<0.001). AMR SNPs have been associated with increased risk of B-ALL and worse prognosis (PMID: 21297632). We also investigated GAs enriched in specific ancestries. B-ALL AMR pts were enriched for GAs in IL7R, IGH, CRLF2, JAK2, and IKZF1 compared to other ancestries in B-ALL (Fig 1B). These genes were associated with the high-risk Philadelphia chromosome-like ALL (Ph-like ALL) molecular subtype of B-ALL (PMID: 30181314). We found 33% of all B-ALL contained GAs consistent with Ph-like ALL (PMID: 30181314). While we noted enrichment of AMR pts in the overall B-ALL cohort, we identified additional enrichment in the Ph-like B-ALL cohort with 47% of Ph-like B-ALL pts being of AMR ancestry (OR=1.85, p<0.001). AMR pts accounted for almost half the Ph-ALL pts in this cohort; however, even in B-ALL pts without Ph-like genomic features, 32% were of AMR ancestry suggesting this enrichment is not simply due to increased CGP testing in Ph-ALL. In diffuse large B cell lymphoma (DLBCL), we found pts to be primarily of EUR ancestry, however we identified ancestry bias in GAs (Fig 1C). CD79B alterations were enriched in DLBCL pts of SAS ancestry, although not significant after FDR correction, consistent with previous reports of increased Activate B-Cell (ABC) cell of origin (COO) subtype and BTK signaling in pts from South East Asia (PMID: 31189540). CDKN2A, also frequently altered in ABC COO subtype, trended towards enrichment in EAS ancestry. CUX1, a tumor suppressor involved in PI3K signaling, was strongly enriched in AFR pts in both DLBCL and B-ALL. One CUX1 insertion variant (G870_G871insSGG) was particularly common in AFR pts with BCL (7/9 AFR, 2/9 AMR), which has been reported previously in Myelodysplastic syndromes (PMID: 24030381). CUX1 alterations have been reported to be associated with increased PI3K signaling suggesting in part PI3K inhibitor trials should proactively include pts of AFR ancestry (PMID: 24316979). Finally, EZH2 alterations were slightly enriched in AMR DLBCL pts, but showed no ancestry bias in follicular lymphoma (FL) pts, of interest given the recent EZH2 inhibitor approval in FL. Conclusions: This study described multiple important genomic differences in BCL using genomic ancestry rather than patient-reported descriptive variables. Enrichment of AMR ancestry was observed in B-ALL overall, and in Ph-like B-ALL. In addition, enrichment of CUX1 alterations was observed in both DLBCL and B-ALL of AFR ancestry. While precision medicine holds the promise to advance cancer care, many acknowledge the potential to unintentionally deepen existing health disparities (PMID: 31112478). Further analysis of ancestry informative markers in BCL, including enrichment of ancestry markers in specific cancer subtypes and ancestry-associated enrichment of specific GAs, may lead to insights into cancer biology and contribute to ongoing cancer health disparities research. Disclosures Moore: Foundation Medicine, Inc: Current Employment; Roche Holdings: Current equity holder in publicly-traded company. Evens:Abbvie: Consultancy, Honoraria; Mylteni: Consultancy, Honoraria; Research To Practice: Honoraria, Speakers Bureau; MorphoSys: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Pharmacyclics: Consultancy, Honoraria; Merck: Consultancy, Honoraria, Research Funding; Epizyme: Consultancy, Honoraria, Research Funding; Seattle Genetics: Consultancy, Honoraria, Research Funding. Newberg:Roche Holdings: Current equity holder in publicly-traded company; Foundation Medicine, Inc: Current Employment. Severson:Foundation Medicine, Inc: Current Employment; Roche Holdings: Current equity holder in publicly-traded company. Mills:Foundation Medicine, Inc: Current Employment; Abbvie: Current equity holder in publicly-traded company; Roche Holdings: Current equity holder in publicly-traded company; Abbott: Current equity holder in publicly-traded company; Merck: Current equity holder in publicly-traded company. Vergilio:Roche Holdings: Current equity holder in publicly-traded company; Foundation Medicine, Inc: Current Employment. Trabucco:F. Hoffmann-La Roche, Bristol-Myers Squibb Co., BioNTech: Current equity holder in publicly-traded company; Patent pending with Foundation Medicine and Genentech: Patents & Royalties: Patent pending; Foundation Medicine, Inc.: Current Employment; Bristol-Myers Squibb Co: Current equity holder in publicly-traded company; BioNTech: Current equity holder in publicly-traded company; Loxo Oncology: Divested equity in a private or publicly-traded company in the past 24 months. Ganesan:M2GEN: Research Funding; Foundation Medicine, Inc: Consultancy; Inspirata: Consultancy; Merck: Consultancy, Current Employment, Current equity holder in publicly-traded company; Silagene: Consultancy; Foghorn Therapeutics: Consultancy; Roche: Consultancy; Novartis: Consultancy.
Dissertations / Theses on the topic "E.B. Moore and Co"
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Ivanauskaitė, Ilma. "Mokslinio žurnalo tinklalapio kūrimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20090618_182844-59741.
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Baigiamajame magistro darbe nagrinėjamas mokslinio žurnalo tinklalapio kūrimas. Atliktas kuriamo tinklalapio palyginimas su kitų universitetų ar institutų mokslinių žurnalų tinklalapiais. Taip pat atliktas palyginimas ir su užsienio mokslinių žurnalų tinklalapiais. Darbe apžvelgiami MySQL duomenų bazėse naudojami paieškos algoritmai. Aptariamas B medžio paieškos algoritmas, elemento įterpimas bei šalinimas iš B medžio. Taip pat aptariamas Turbo Boyer-Moore paieškos algoritmas. Pateikiami tinklalapyje atlikti patobulinimai, tokie kaip puslapis keliomis kalbomis, paieškos langas, straipsnių pateikimo dizainas ir kt. Atlikus tinklalapių palyginimą bei tinklalapio patobulinimą, pateikiamos baigiamojo darbo išvados bei pasiūlymai, tokie kaip paieška pagal reikšminius žodžius iš reikšmių sąrašo, paieškos žodžio pasiūlymas, CSS failų bei turinio valdymo sistemos panaudojimas. Apžvelgiamos PHP programavimo kalbos funkcijos skirtos rašybos klaidų taisymams.The thesis analyse website development of scientific journal. The developed website comparison with others universities and institutes scientific journal websites was made. There was also made a comparison with foreign scientific journal websites. Thesis reviews search algorithms that are used in MySQL databases. The B tree search algorithm, insertion and elimination of element in it are described. There is also presented Turbo Boyer – Moore search algorithm. The thesis presents improvements of website, such as pages in several languages, search page, design of articles presentation and others. Conclusions and proposals, such as search by key words from the list, search word proposal, usage of CSS files and content management system are made after comparisons and improvements of website. PHP functions for spelling mistakes are described.
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Bollero, Real Alberto. "Isotropic nanocrystalline (Nd,Pr)(Fe,Co)B permanent magnets." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2003. http://nbn-resolving.de/urn:nbn:de:swb:14-1069758225796-19366.
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Nanokristalline Permanentmagnete zeigen ungewöhnliche magnetische Eigenschaften aufgrund von Oberflächen- und Grenzflächeneffekten, die verschieden von denen massiver oder mikrokristalliner Materialien sind. Diese Arbeit zeigt Ergebnisse einer systematischen Untersuchung der Beziehung zwischen Mikrostruktur und magnetischen Eigenschaften von isotropen nanokristallinen (Nd,Pr)(Fe,Co)B-Permanentmagneten. Hochkoerzitive Magnete vom Typ (Nd,Pr)FeB wurden durch hochenergetisches Mahlen in der Kugelmühle oder Rascherstarrung hergestellt. Der Einfluss geringer Mengen von Zusätzen wie Dy und Zr und die Substitution von Nd durch Pr auf die magnetischen Eigenschaften wird dargestellt. Weiterhin wurde eine Einschätzung des Warmumformverhaltens dieser Materialien durchgeführt. Hochenergetisches Kugelmahlen einer Legierung mit der Anfangszusammensetzung Pr9Nd3Dy1Fe72Co8B6.9Zr0.1 führte, nach Glühbehandlung, zu fast einphasigem Magnetpulver mit einem maximalen Energieprodukt von (BH)max~140 kJm-3. Das hochenergetische Kugelmahlen wurde zu einer sehr vielseitigen Technik zur Herstellung hochleistungsfähiger Nanokompositmagnete weiterentwickelt. Das Zulegieren unterschiedlicher Anteile von weichmagnetischem alpha-Fe ist damit sehr effektiv möglich. Der Zusatz von 25 Gew.-% alpha-Fe führt zu einem hohen (BH)max=178kJm-3. Dies wird auf eine sehr effektive Austauschkopplung zwischen den hart- und weichmagnetischen Phasen zurückgeführt. Die Natur der intergranularen Wechselwirkungen kann durch die Wohlfarth´sche Remanenzanalyse (?deltaJ-plot¡§) beschrieben werden. Im speziellen wurden deltaJ-Diagramme für verschiedene (i) alpha-Fe Gehalte, (ii) Korngrößen und (iii) Austauschlängen erstellt. Es konnte gezeigt werden, dass in den Nanokompositmagneten auf Pr-Basis keine Spinumorientierung auftritt. Abschließend zeigt die Arbeit die Möglichkeit der Nutzung einer mechanisch aktivierten Gas-Festkörper-Reaktion auf, mit der eine sehr feinkörnige Mikrostruktur erhalten wird. Die Untersuchungen wurden mit stöchiometrischen Nd2(Fe1-xCox)14B-Legierungen begonnen (x=0-1). Die Verbindungen wurden unter höheren Wasserstoffdrücken und Temperaturen gemahlen, wodurch sie zu NdH2+delta und krz-(Fe,Co) (x=0-0.75) oder kfz-Co (x=1) entmischt wurden. Die Korngrößen des rekombinierten Nd2(Co,Fe)14B-Materials liegen im Bereich von 40-50 nmNanocrystalline permanent magnets present unusual magnetic properties because of surface/interface effects different from those of bulk or microcrystalline materials. This work presents results of a systematic investigation of the relationship between microstructure and magnetic properties in isotropic nanocrystalline (Nd,Pr)(Fe,Co)B permanent magnets. Highly coercive (Nd,Pr)FeB-type magnets have been produced using high energy ball milling and melt-spinning. The influence of small amounts of additives, Dy and Zr, and the substitution of Nd by Pr on the microstructural and magnetic properties are shown. An assessment of the hot deformation behaviour has been carried out. Intensive milling of an alloy with starting composition Pr9Nd3Dy1Fe72Co8B6.9Zr0.1 yields, after annealing treatment, nearly single-phase magnet powders with a maximum energy product (BH)max?î140kJm-3. Co has a beneficial effect on the intrinsic magnetic properties but also on the microstructure, with a mean grain size of 20nm. Intensive milling is used to produce high-performance nanocomposite magnets by blending this latter alloy with different fractions of soft magnetic alfa-Fe. Addition of 25wt.% alfa-Fe leads to a high (BH)max=178 kJm-3 due to an effective exchange-coupling between the hard and the soft magnetic phases. The intergrain interactions between the crystallites of the nanocomposite structure are analysed. Demagnetisation recoil loops of the nanocomposite magnets show relatively open minor loops due to the exchange-spring mechanism. Information about the intergrain interactions during demagnetisation are obtained by plotting the deviation of the demagnetising remanence from the Wohlfarth-model (¡§deltaJ-plot¡¨). Exchange-coupling phenomena are studied by analysing the evolution of the corresponding deltaJ values when varying (i) the alfa-Fe content, (ii) the annealing temperature, i.e. the grain size and (iii) the measurement temperature. Low temperature measurements do not reveal any sign of spin reorientation for these Pr-based nanocomposite magnets. The work concludes showing the possibility of using a mechanically activated gas-solid reaction to obtain an effective grain refined microstructure starting from stoichiometric Nd2(Fe1-xCox)14B alloys (x=0-1). These compounds were milled under enhanced hydrogen pressure and temperature leading to their disproportionation into NdH2+delta and bcc-(Fe,Co) (x=0-0.75) or fcc-Co (x=1). Grain sizes of recombined Nd2(Fe,Co)14B materials were found to be 40-50nm
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Matthews, Gail Veronica National Centre in HIV Epidemiology & Clinical Research Faculty of Medicine UNSW. "Therapeutic strategies in HIV and Hepatitis B co-infection." Awarded by:University of New South Wales. National Centre in HIV Epidemiology & Clinical Research, 2009. http://handle.unsw.edu.au/1959.4/44538.
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Individuals with HIV-HBV coinfection are at risk of accelerated hepatic fibrosis, and end stage liver disease is now a major cause of morbidity and mortality in this population. For many years lamivudine (3TC) monotherapy was the only effective treatment for HBV in coinfected individuals, but its use was complicated by the frequent development of HBV drug resistance, and loss of virological suppression. With the availability of new potent antivirals for HBV, including tenofovir (TDF), therapeutic options for HIV-HBV coinfected individuals have increased, although the management of HBV disease in this population is still often suboptimal. This thesis explores through a series of published papers, issues in the current management of HIV-HBV coinfected individuals_ Chapter 1 describes a high incidence of 3TC resistance in HIV-HBV individuals on extended 3TC monotherapy, and in particular, a significant proportion with complex HBV-drug resistant mutants, with potential public health implications. In Chapter 2 the benefits of TDF ???induced virological suppression on parameters of end stage liver disease are described. Chapters 3 and 6 explore the role of TDF as monotherapy, or in combination with 3TC, within HBV-active antiretroviral therapy (ARn. No benefit for TDFj3TC combination versus TDF monotherapy is observed in treatment naive individuals; although a potential benefit for combination therapy is observed in treatment experienced subjects. In Chapter 4 a high rate of hepatic flare (HF) after initiation of HBV-active ART is described, and potential predictors of flare including elevated baseline ALT and HBV DNA are identified to suggest HBV immune restoration disease (IRD) as the major underlying cause of HF in this study. Chapter 5 discusses the immunopathogenesis of HBV IRD in more detail and proposes guidelines for clinical management. In summary the thesis finds that the therapeutic outlook for HIV-HBV coinfected individuals is generally optimistic, although several further research areas are identified, particularly in middle and low- income settings where the burden of HIV and HBV disease is greatest.
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Wang, Xiao Qian. "The Impact of Hepatitis B co-infection on the HIV Reservoir." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/22895.
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Hepatitis B virus (HBV) co-infection increases overall and liver-related mortality in people living with HIV, yet the relationship between these two viruses is still poorly understood. We determined whether levels of HIV were associated with markers of HBV infection, immune activation and inflammation or liver damage. We also designed an assay to sequence full-length HIV RNA in order to further validate our findings. HIV-HBV co-infected and HIV mono-infected participants, naïve to ART, were recruited in Bangkok, Thailand as part of a prospective observational cohort study. HIV proviruses were sequenced from peripheral blood (PB) CD4+ T cells using full-length individual proviral sequencing. Spearmans rank correlations tests were performed to determine associations. RNA extraction and cDNA synthesis protocols based on previously established Single Copy Assay and Single Genome Sequencing methods were optimised to yield a full-length HIV fragment. The 1337 and 285 HIV proviruses were sequenced from 19 HIV-HBV co-infected and 6 HIV mono-infected individuals respectively, although 2 co-infected and 1 mono-infected individual was excluded due to infection with non-subtype AE HIV virus. More genetically intact proviruses (22-1000 copies/106 cells, p=0.02) was observed in the co-infected individuals compared to the mono-infected. For the HIV-HBV cohort, the levels of soluble CD14, LPS and AST in the blood were significantly correlated with the frequency and the genetic diversity of intact HIV proviruses (p<0.05). However, markers of HBV disease (HBV DNA, HBsAg, HBeAg status) and markers of inflammation in both the blood and liver (CXCL10, CCL2, and CXCR3) were not found to be significantly associated with levels of intact HIV (p>0.05). We were also able to present a preliminary HIV RNA sequencing assay to sequence ~90% of the HIV RNA genome with a single amplicon. During HIV-HBV co-infection, the frequency and genetic diversity of the intact proviruses within PB CD4+ T cells from the HIV-HBV co-infected individuals appears to be independent of levels of markers of HBV or liver damage, but may be associated with markers of immune activation.
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Fajnorová, Markéta. "Návrh marketingové strategie firmy Inspur Group Co. ltd. pro český trh." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-82017.
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The diploma thesis is structured into three chapters, while the first chapter informs about theoretical concept of B-2-B marketing, defines basic specifics of B-2-B market and concerns about actual trends and frequent mistakes, which are made while preparing B-2-B marketing strategy. Next chapter informs about actual situation on the server market in the Czech Republic and mainly focuses on the external and internal environment of the firm. The last chapter is based on the personal discussion with potential distribution and service partners that provided useful information about the concurrence, actual situation on the market and defined trade requirements towards Inspur.
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Del, Nagro Christopher J. "B cell co-receptors CD19 and CD21 in tolerance and auto-immunity." Diss., Connected to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3190009.
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Thesis (Ph. D.)--University of California, San Diego, 2005.Title from first page of PDF file (viewed March 14, 2006). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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Prince, Darren William. "The Co-Transcriptional Response of Intracellular Group B Streptococcus (GBS) and Monocytes." Thesis, Griffith University, 2019. http://hdl.handle.net/10072/389087.
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Group B Streptococcus (GBS) is a species of gram positive bacteria representing a significant human pathogen; namely, as the most prolific cause of neonatal disease and mortality globally, but also increasingly reported in adult disease (especially among the elderly and those with compromised immune systems). The first chapter of this thesis reviews the extensive literature covering GBS; with a focus on classification and disease. Selected virulence factors are also discussed. In chapter 2, eight strains of GBS were selected for whole genome sequencing by Third Generation, Pacific Biosystems (PacBio) sequencing technology. A protocol was optimised to provide sufficient, high quality genomic preparations from multiple strains of GBS – suitable for the PacBio technology. Using a sequenced strain of GBS from chapter 2, an infection model was optimised in chapter 3 for the purpose of providing quality RNA for co-transcript analysis. U937 human monocytes were infected with GBS (strain 874391) and the host/pathogen RNA prepared from the same reaction (monocytes with internalised GBS) – with an emphasis on yielding sufficient pathogen RNA; which can sometime be an impediment for co-transcript studies. Pathogen RNA derived from the optimised infection protocol was demonstrated to amplify with RT-qPCR for 12 tested GBS genes (cylE, 1010, rib, czcD, pil2B, cpsE, scpB, htp, cfb, copA, hvgA and maeA). In chapter 4, RT-qPCR was used to analyse differential gene expression from the mixed, host/pathogen RNA. Twelve human genes and 12 GBS genes were assessed for differential gene expression. Seven of the tested human genes (IL8, IL1A, IL1B, IL10, TNF, LMO2 and MCP-1) and 6 of the tested GBS genes (scpB, 1010, rib, czcD, htp, hvgA) were significantly upregulated in RNA derived from the infection samples. Of the GBS genes tested, htp was the most upregulated. An htp knockout mutant of GBS strain 874391 (Δhtp) was constructed for chapter 5 of this thesis to assess the impact of htp transcription on GBS survival in an infection context. The infection assays optimised in chapter 3 were performed with the Δhtp GBS construct. Contrary to expectation, the Δhtp GBS construct survived the internalised environment of the monocytes in significantly higher numbers than the wild-type over 48 hours of infection.Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Medical Science
Griffith Health
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Rivier, Elodie. "La co-création de service B to B : Une étude des déterminants de l’engagement des entreprises dans un processus d’innovation des services." Thesis, Orléans, 2014. http://www.theses.fr/2014ORLE0502.
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Au vu du contexte actuel (mondialisation des échanges, concurrence, innovations technologiques…), les entreprises doivent trouver les moyens de proposer des produits et services toujours plus innovants pour se différencier. C’est pourquoi, elles font de plus en plus appel aux compétences des clients pour concevoir leurs offres qui correspondront davantage à leurs besoins. Cette pratique qui suscite un réel engouement auprès des managers est appelée « co-création ».Or, d’après la littérature, il semblerait que peu de recherches ne se sont intéressées aux raisons pour lesquelles certaines entreprises sont plus prédisposées que d’autres à co-créer des services dans le contexte interorganisationnel (Business-to Business, B to B). Pourtant, cette question est fondamentale. En effet, s’il est démontré que certains facteurs favorisent l’adhésion des clients et la gestion de projets de co-création, les organisations pourront mieux choisir des partenaires (candidats) à un projet de co-création. Ainsi, notre travail de recherche propose de répondre à la question suivante : Pourquoi certaines entreprises sont-elles plus disposées à co-créer un service alors que d’autres le sont moins ?Dès lors, après avoir réalisé un état de l’art sur la co-création de services, nous menons deux études qualitatives auprès de dirigeants et de clients B to B impliqués dans des démarches de co-création de services innovants. La troisième étude de nature quantitative est réalisée auprès d’un échantillon de prestataires de services destinés aux entreprises afin de tester nos hypothèses de recherche. Les résultats obtenus ont permis d’identifier des critères à la fois organisationnels (spécifiques à l’entreprise) et sectoriels (c’est-à-dire, relatifs au marché) explicatifs de la prédisposition et du degré d’implication des entreprises dans un processus de co-création. D’un point de vu managérial, cette recherche souligne les bonnes pratiques à mettre en place au sein des organisations avant d’initier cette démarche collaborativeIn the current world context (globalization, competition, technological innovations,.), companies must look for new ways to offer more innovative goods and services. Therefore, they require customer’s competencies to design offerings that meet their needs. This practice which is raising a great deal of enthusiasm from the managers is called “co-creation”.An examination of the existing literature on services suggests that little has been done on the reasons why some companies are more disposed to engage in a B to B service co-creation process while others are less disposed to do so. Yet, this is an important issue. Indeed, if we can show that there are some criteria which can be used to identify potential co-creators and that facilitate the management of co-creation projects, then organizations could use this knowledge to select their partners in a co-creation process.In the light of the foregoing, our research study seeks to answer the following question: Why are some B-to-B service providers more disposed to co-create services than others?After a literature review on service co-creation, we conduct two qualitative studies with leaders and B to B customers involved in innovative service co-creation projects. The third study that is quantitative surveys a number of service providers in order to test our research hypothesis.Our empirical results allow us to identify firm-level and industry-level criteria relevant for explaining businesses’ willingness to engage in a co-creation process as well as their level of involvement in this process. From a managerial perspective, the present research also underlines the best practices to implement in service organizations before starting such a collaborative approach
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Márquez, Lobato Yolanda. "Study of the monofilar suture based on the segmented copolymer GL-b-(GL-co-TMC-co-CL-)-b-GL thermal behavior, degradability and incorporation of active agents : polymers and biopolymers." Doctoral thesis, Universitat Politècnica de Catalunya, 2016. http://hdl.handle.net/10803/404331.
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Biomaterials based on block segmented copolymers constituted by hard and soft segments have attracted much attention for biomedical applications in the last decades, specifically as absorbable monofilament sutures. Polyglycolide has demonstrated to be a good candidate to constitute the hard segment due to its biodegradability and high stiffness, whereas the incorporation of different monomers (e.g. -caprolactone, trimethylene carbonate or glycolide) in a random distribution as soft segment promotes material flexibility and enhances in vitro degradation rates. Resulting material properties can be tailored by the combination of different ratios of hard and soft segments and the specific monomer composition.
In this Thesis the study of a tricomponent segmented copolymer commercially marketed as Monosyn® by B. Braun Surgical as an absorbable monofilament suture is presented. The main goals of the work concern to: a) the complete physical characterization that involves the study of the crystallization kinetics and thermal stability, b) the study of the degradation behavior and the associated microstructural changes, c) the evaluation of the capability to improve the performance of Monosyn® by adding compounds with pharmacological activity and d) the production of nanofibers to be employed as reinforcing agents.
Isothermal and non-isothermal crystallizations were followed by different techniques (e.g. optical microscopy, differential scanning calorimetry and time-resolved SAXS experiments in a synchrotron radiation facility). The composition of the soft segment influenced in the crystallization of the segmented copolymer as could be deduced by comparison with reported data on similar bicomponent systems.
Hydrolytic degradation was carried out at different temperatures and in buffered media of a continuous range of pH. Surface morphology of hydrolyzed sutures showed the formation of longitudinal and circumferential cracks in the outer and inner part of the suture, respectively. These fractures were associated to the existence of interfibrillar and interlamellar amorphous domains as was revealed by SAXS experiments.
To explore the potential applications of Monosyn® as an absorbable monofilament suture with pharmacological activity, different drugs were incorporated. Moreover, the use of an amorphous copolymer coating was also evaluated. The first group of drugs selected were biguanide compounds (i.e. chlorhexidine and polyhexametilen biguanide), which have a well-recognized bactericide activity. Specifically, the effectiveness of using a coating was proved as well as the influence of drug molecular size in the activity. The study of the loading process, release behavior and pharmacological activity was completed considering an antibiotic (chloramphenicol) and a healing agent (captopril).
Finally, nanofibers of the selected copolymer were prepared by means of the electrospinning technique. These nanofibers were also loaded with pharmacological drugs and used as reinforcing agent of biodegradable polymer matrices. In order to obtain appropriate fabrics different fiber compositions and electrospun set up configurations were tested.En las últimas décadas, los biomateriales basados en copolímeros segmentados, constituidos por segmentos duros y blandos, han atraído el un creciente interés para una amplia gama de s aplicaciones biomédicas, especialmente como suturas monofilares absorbibles. Se ha demostrado que la poliglicolida es una buena candidata para constituir el segmento duro debido a su biodegradabilidad y a su alta rigidez, mientras que la incorporación de distintos monómeros (por ejemplo, -caprolactona, carbonato de trimetileno o glicolida) en una disposición estadística como segmento blando promueven la flexibilidad del material y mejoran la velocidad de degradación in vitro. Las propiedades de los materiales resultantes pueden ajustarse combinando diferentes proporciones de los segmentos duro y blando, y con una composición específica de monómero. En esta Tesis se presenta el estudio del copolímero segmentado tricomponente comercializado por B.Braun Surgical como sutura absorbible monofilar con el nombre de Monosyn®. Los principales objetivos de este trabajo son: a) la caracterización física completa que incluye el estudio de estabilidad térmica y cinéticas de cristalización, b) el estudio de la degradación y los cambios microestructurales asociados, c) la evaluación de la mejora del uso de la sutura añadiendo componentes con actividad farmacológica, y d) la producción de nanofibras para utilizarlas como agentes reforzantes. Las cristalizaciones isotérmicas y no isotérmicas se siguieron mediante distintas técnicas (microscopía óptica, calorimetría diferencial de barrido y experimentos de difracción de rayos X de bajo ángulo). La composición del segmento blando influyó en la cristalización del copolímero segmentado, como era de esperar por la comparación con los datos publicados del sistema bicomponente similar. La degradación hidrolítica fue llevada a cabo a distintas temperaturas con disoluciones tamponadas en un rango continuo de pH. La morfología de la superficie de las suturas hidrolizadas mostró la formación de fracturas longitudinales y circunferenciales en la zona externa e interna de la sutura, respectivamente. Estas fracturas se asociaron a la existencia de dominios amorfos interfibrilares e interlamelares, tal y como se corroboró mediante los experimentos de difracción de rayos X de bajo ángulo. Para explorar las aplicaciones potenciales de Monosyn® como sutura absorbible monofilar con actividad farmacológica, se incorporaron distintos fármacos. Además, se evaluó el uso de un copolímero amorfo como recubrimiento. El primer grupo de fármacos seleccionados corresponden a la familia de las biguanidas (clorhexidina y polihexametilen biguanida), conocidas por su actividad bactericida. En particular se probó la efectividad de utilizar un recubrimiento y la influencia del tamaño molecular del fármaco en su actividad. El estudio del proceso de carga, el perfil de liberación y la actividad farmacológica se completó considerando también un antibiótico (cloranfenicol) y un agente cicatrizante (captopril). Por último, se prepararon nanofibras del copolímero seleccionado mediante la técnica del electrohilado. Estas nanofibras se cargaron con fármaco y se utilizaron como agentes reforzantes de matrices poliméricas biodegradables. Con el propósito de conseguir unos tejidos apropiados, se probaron distintas composiciones de fibras y diferentes configuraciones en el montaje del sistema de electrohilado.
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Mayot, Hervé. "Contribution à l'étude cristallographique et magnétique de composés intermétalliques R–Co–B et R–Fe–B (R ≡ élément de terres rares)." Phd thesis, Grenoble 1, 2008. http://www.theses.fr/2008GRE10229.
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Nous nous sommes attaché à étudier les liens entre propriétés cristallographiques et magnétiques de phases intermétalliques R M-B où R est un élément de terres rares, l'yttrium ou le thorium et M un métal de transition 3d. La présence de bore dans l'environnement atomique des sites de métaux de transition, notamment, agit fortement sur les propriétés magnétiques tant à l'échelle macroscopique que microscopique. Nous apportons une contribution à l'étude des propriétés magnétiques particulières du composé YCo4B, composé modèle et de référence de la famille Rn+mCo3n+5mB2n. L'anisotropie magnétocristalline originale de ce composé est caractérisée à la fois par une réorientation de spin et un processus d'aimantation du premier ordre. Elle s'avère également fort sensible à la pression comme l'ont montré nos mesures magnétiques. La substitution du fer au cobalt dans les composés RCo4B est possible et donne lieu à un schéma préférentiel comme l'illustre nos mesures de diffraction des neutrons. En combinant ces résultats à des mesures magnétiques diverses et de spectroscopie Mössbauer, les propriétés magnétiques de chaque site cristallographique de métaux de transition 3d ont pu être particularisées. Nous avons étudié la solution solide Y1-xThxCo4B et montré l'existence d'une substitution préférentielle du thorium à l'yttrium sur un site cristallographique. Ces deux éléments R non magnétiques ont des effets différents sur les propriétés magnétique des composés. Par comparaison à des études magnétiques sous pression, il a été possible de montrer que ces différences sont principalement dues aux différences de configuration électronique entre le thorium et l'yttrium et peu aux évolutions structurales induites par la substitution. De nouveaux composés de la famille structurale Rn+mCo3n+5mB2n ont été mis à jour récemment. Nous présentons des études des conditions de synthèses et des structures magnétiques de quelques phases R3Co13B2 et R5Co19B6. Le composé Pr5Co19B6 présente notamment des anomalies magnétiques interprétables comme une réorientation de spin à basse température. Nous présentons des résultats d'absorption des rayons X réalisés sur plusieurs compositions de la solution solide CeCo12-xFexB6. Dans cette structure, le cérium présente un état de valence intermédiaire qui évolue notablement en fonction de la teneur en fer. Enfin, nous avons précisé les conditions de synthèse de phases métastables Nd2Fe23B3 et Y3Fe62B14, très riches en fer. Ces structures originales présentent de nombreux types d'environnements atomiques du fer ce qui en fait des composés aux propriétés magnétiques intéressantes. Nous avons notamment montré les évolutions inhabituelles de ces propriétés magnétiques entre les états amorphe et cristallisé de ces alliagesWe studied the relationship between crystallographic and magnetic properties in R-M-B intermetallic phases where R is a rare earth element, yttrium or thorium and M a 3d transition metal. The presence of boron in the transition metal atomic environment dramatically modifies the magnetic properties both at macroscopic and microscopic scales. Through this experimental work, we investigated the magnetic properties of YCo4B compound, the reference compound of the Rn+mCo3n+5mB2n family, and some RCo4-xFexB. The original magnetocrystalline anisotropy of YCo4B presents both a spin reorientation and a first order magnetisation process. It also presents a great sensitivity to an applied pressure. Using neutron diffraction, we demonstrated that the iron for cobalt substitution in RCo4B compound give rise to a preferential substitution scheme. Combining these results to those of different magnetic measurements and Mössbauer spectroscopies, we determined the contributions of each crystallographic sites of transition metals to the macroscopic magnetic properties. We studied the Y1-xThxCo4B solid solution and shown the appearance of preferential thorium for yttrium substitution on one of the R crystallographic sites. These two R elements are not magnetic but the magnetic properties however drastically depend on the thorium / yttrium ratio. Through comparison to magnetic measurements under pressure, we could demonstrate that these differences originates mostly from the difference of electronic configuration between both elements and not only from structural evolution caused by the substitution. New compounds of formulae R3Co13B2 and R5Co19B6 had been recently discovered among the Rn+mCo3n+5mB2n structural family. We present studies of the synthesis conditions and the magnetic structures of some of these new phases. In particular, the Pr5Co19B6 compound presents magnetic anomalies interpreted as a spin reorientation transition occuring at low temperature. We present results of X rays absorption on selected compositions of the CeCo12-xFexB6 solid solution. In this structure, one can observe an intermediate valence state for cerium which is sensitive to the iron content. To finish, we studied the synthesis conditions of the Nd2Fe23B3 and Y3Fe62B14 metastable phases. These original structures show numerous atomic environments for iron giving rise to interesting magnetic properties. We observed unusual evolution of their magnetic properties between amorphous and crystalline state of these alloys
Books on the topic "E.B. Moore and Co"
1
Moss, Alan. Richard B. Moore library printed catalogue. [Cave Hill, Barbados: S.G. Moss, 1987.
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Hopkins, Richard. The family of Max B. Moore. [[St. Louis, Mo.]: R. Hopkins, 1988.
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Moore, Richard B. Richard B. Moore, Caribbean militant in Harlem: Collected writings, 1920-1974. Bloomington: Indiana University Press, 1988.
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B, Moore Richard. Richard B. Moore, Caribbean militant in Harlem: Collected writings, 1920-1972. Bloomington: Indiana University Press, 1992.
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B, Moore Richard. Richard B. Moore, Caribbean militant in Harlem: Collected writings, 1920-1972. Bloomington: Indiana University Press, 1988.
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B, Moore Richard. Richard B. Moore, Caribbean militant in Harlem: Collected writings 1920-1972. Bloomington: Indiana University Press, 1988.
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Eberhart, L. D. The collecting of Deringers manufactured by Moore, National, and Colt. Gainesville, GA: Vanns Tavern Press, 2011.
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Kruk, Max. Bankiers in ihrer Zeit: Die Männer von B. Simons & Co. Frankfurt am Main: F. Knapp, 1989.
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Trowbridge & Livingston and Williams Sarah, eds. B. Altman & Company department store building: [report]. [New York, N.Y.]: Landmarks Preservation Commission, 1985.
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Marsteller, Charles M. St. Mary's Co, MD--ancestry of President Barack Obama (b. 1961). San Francisco CA (835 Turk Street #608): Charles M. Marsteller, 2015.
Find full textBook chapters on the topic "E.B. Moore and Co"
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Falkner, David E. "Benedetto Castelli and J. B. Liebknecht: , , and." In The Patrick Moore Practical Astronomy Series, 97–103. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-80309-4_11.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-Cr (112)." In Landolt-Börnstein - Group III Condensed Matter, 51–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_12.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-Er (113)." In Landolt-Börnstein - Group III Condensed Matter, 53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_13.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-Fe (114)." In Landolt-Börnstein - Group III Condensed Matter, 54–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_14.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-Mn (115)." In Landolt-Börnstein - Group III Condensed Matter, 60–65. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_15.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-Nb (116)." In Landolt-Börnstein - Group III Condensed Matter, 66–69. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_16.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-Ni (117)." In Landolt-Börnstein - Group III Condensed Matter, 70. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_17.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-P (118)." In Landolt-Börnstein - Group III Condensed Matter, 71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_18.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-Si (119)." In Landolt-Börnstein - Group III Condensed Matter, 72–83. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_19.
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Carow-Watamura, U., D. V. Louzguine, and A. Takeuchi. "B-Co-Ti (120)." In Landolt-Börnstein - Group III Condensed Matter, 84–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-13850-8_20.
Full textConference papers on the topic "E.B. Moore and Co"
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Kumabe, Soh, and Takanori Maehara. "Convexity of b-matching Games." In Twenty-Ninth International Joint Conference on Artificial Intelligence and Seventeenth Pacific Rim International Conference on Artificial Intelligence {IJCAI-PRICAI-20}. California: International Joint Conferences on Artificial Intelligence Organization, 2020. http://dx.doi.org/10.24963/ijcai.2020/37.
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The b-matching game is a cooperative game defined on a graph. The game generalizes the matching game to allow each individual to have more than one partner. The game has several applications, such as the roommate assignment, the multi-item version of the seller-buyer assignment, and the international kidney exchange. Compared with the standard matching game, the b-matching game is computationally hard. In particular, the core non-emptiness problem and the core membership problem are co-NP-hard. Therefore, we focus on the convexity of the game, which is a sufficient condition of the core non-emptiness and often more tractable concept than the core non-emptiness. It also has several additional benefits. In this study, we give a necessary and sufficient condition of the convexity of the b-matching game. This condition also gives an O(n log n + m α(n)) time algorithm to determine whether a given game is convex or not, where n and m are the number of vertices and edges of a given graph, respectively, and α(・) is the inverse-Ackermann function. Using our characterization, we also give a polynomial-time algorithm to compute the Shapley value of a convex b-matching game.
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Ariwardani, Betty Nurizky, Didik Gunawan Tamtomo, and Bhisma Murti. "Path Analysis on the Determinants of Hospital Lost Under INA-CBGS Reimbursement for Patient with Dengue Hemorrhagic Fever in Ngawi Regional Public Hospital, East Java." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.04.35.
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ABSTRACT Background: Hospitals are demanded to be more efficient and effective in providing medical services to avoid losses in the era of National Health Insurance. The increase in cases of dengue hemorrhagic fever (DHF) is a burden on the cost of medical services in Indonesia. This study aimed to examine the determinants of hospital lost under Indonesia Case-Based Groups (INA-CBGs) reimbursement for patients with dengue hemorrhagic fever (DHF). Subjects and Method: A cross-sectional study was carried out at dr. Soeroto hospital, Ngawi, East Java, from September to October 2019. A sample of 200 in-patients was selected by simple random sampling. The dependent variable was tariff difference between INA-CBGs and hospital cost. The independent variables were class of treatment, length of stay, blood transfusion, co-morbidity, and complication. The data were obtained from DHF in-patients’ medical record. The data were analyzed by path analysis model run on Stata 13. Results: Tariff difference was directly and positively affected by length of stay (b= 2.77; 95% CI= 1.78 to 3.75; p<0.001), blood transfusion (b= 2.95; 95% CI= 0.36 to 5.54; p= 0.025), patients age (b= 0.09; 95% CI= -1.52 to 1.71; p= 0.907), co-morbidity (b= 0.58; 95% CI= -1.07 to 2.22; p= 0.491), and complication (b= 0.34; 95% CI= -1.69 to 2.36; p= 0.743). Tariff difference was directly and negatively affected by type of treatment (b= -0.81; 95% CI= -2.02 to 0.40; p= 0.191). Tariff difference was indirectly affected by co-morbidity, complication, class of treatment, and patient age. Conclusion: Tariff difference is directly and positively affected by length of stay, blood transfusion, patient age, co-morbidity, and complication. Tariff difference is directly and negatively affected by type of treatment. Tariff difference is indirectly affected by co-morbidity, complication, class of treatment, and patient age. Keywords: INA CBGs, hospital tariff, care cost, dengue hemorrhagic fever Correspondence: Betty Nurizky Ariwardani. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta, Central Java, Indonesia. Email: bettyna175@-gmail.com. Mobile: 082233243164. DOI: https://doi.org/10.26911/the7thicph.04.35
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Alnuaimi, Aiysha, and Robert Joslin. "ANALYSING THE IMPACT OF PMO CULTURE ON PMO SUCCESS." In 10th IPMA Research conference: Value co-creation in the project society. International Project Management Association, Serbian Project Management Association, 2022. http://dx.doi.org/10.56889/azye5590.
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This study looks at the relationship between PMO culture and PMO success from a control theory perspective. PMO success was operationalized using three concepts: (a) domain of control, (b) domain of influence and (c) domain of concern. The motivation of the study is to understand if and how culture types could influence PMO success and what are the attributes of these cultures. Using Cameron and Quinn’s culture model, a cross-sectional, worldwide online survey yielded 219 responses. Analysis was done through factor analysis and moderated hierarchical regression analysis. The factor analysis showed that both clan and market culture types correlate to PMO success. A case study then determined the antecedents of culture types and how they influenced PMO success. PMOs that were more commercially focused, that is, supporting revenue-generating projects, were more market culture oriented, whereas PMOs that were internally focused were clan culture type. The implications for practitioners are that competence profiles of PMO people will need to be aligned to the culture type of the PMO that is linked to PMO success. The results are important for academics as PMOs have different culture types depending on the customers and the clients they serve.
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Daleyev, Dalel, Shervin Rasoulzadeh, and Iva Kovacic. "A Novel Approach of Structural FE Modelling Using 4D Architectural Design Sketches." In 6th IPMA SENET Project Management Conference “Digital Transformation and Sustainable Development in Project Management”. International Project Management Association, IPMA Publications, and Faculty of Civil Engineering, University of Zagreb, Croatia, 2023. http://dx.doi.org/10.5592/co/senet.2022.23.
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This paper describes a novel methodology for a quick structural finite element (FE) modelling of free-form and high-rise structures sketched within a developed 4D semantic, mixed reality sketching application, targeted for early stages of architectural design, followed by a shape inference pipeline. The novel approach presented in this paper intends to estimate structural viability for the architectural concept in the early preliminary draft. A fast collaborative export of geometrical data from the sketching app to the generative algorithm for the assembling of structural topology will be used to define analytical FE model. With pre-defined data, such as material information and the type of load-bearing system, a simple linear-elastic FE calculation will be conducted in order to analyse the structural parts in ultimate (ULS) and serviceability limit states (SLS) and point out the problematic places. Once the decision regarding the architectural design of the sketched structure is made, the compiled FE model will be afterwards transferred to a commercial FE software in order to undergo further, more detailed structural analysis. The advantage of the described modelling method is a) time saving as it generates a model directly upon architectural design, and b) by generation of the plausible FE model in the very early stages of planning and post-editing it during the process.
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Reed, G. P., D. R. Dugwell, and R. Kandiyoti. "Modelling Trace Element Emissions in Co-Gasification of Sewage Sludge With Coal." In ASME Turbo Expo 2002: Power for Land, Sea, and Air. ASMEDC, 2002. http://dx.doi.org/10.1115/gt2002-30672.
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Gasification has attracted considerable interest from water utilities as a sewage sludge disposal option, with the advantages of waste volume reduction, pathogen destruction and energy recovery. Co-gasification with coal in a larger plant (>10 MWt) employing a gas turbine for energy recovery may reduce the risk and cost of this option. However, controlling the release of trace elements such as Pb and Zn in the gas produced may be necessary to avoid corrosion, and to meet environmental requirements. A thermodynamic equilibrium model has been used to make predictions of the speciation of trace elements in the fuel gas from co-gasification of sewage sludge with coal. Experimental data from a pilot scale 2 MWt sewage sludge/coal co-gasification plant with a hot gas filter was used to test the validity of these predictions. No significant amount of Be, Co, Cu, V and Zn was predicted to be in the form of gaseous phase species, and this was confirmed by the experimental data. On the other hand, Hg and Se were predicted to be only present in gas phase species, and this was also confirmed experimentally. The elements As, B, Cd, Pb, Sb and Sn were all predicted to form a larger amount of gaseous species than was observed in the experimental measurements. Refinement of the predictions for As and B by inclusion of specific minor/trace element interactions with Ni and Ca respectively gave a better agreement with the experimental data. Whilst the experimentally-observed lowering of Pb emissions by reduction of the gas cleaning temperature from 580 °C to 450 °C was qualitatively predicted, the concentration of Pb in the fine dust removed by the hot gas filter indicates condensation at higher temperatures than predicted. The absence of thermodynamic data for the more complex minerals and adsorbed species that may be formed is thought to account for some of these differences.
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Wagner, Mathias, Peter Schneider, Andreas Hinnerichs, Thomas Bruder, and Andre´ Stork. "FunctionalDMU: Co-Simulation of Mechatronic Systems in a Virtual Environment." In ASME 2011 World Conference on Innovative Virtual Reality. ASMEDC, 2011. http://dx.doi.org/10.1115/winvr2011-5534.
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Digital Mock-up (DMU) is a widely introduced technology to virtually investigate geometrical and mechanical product properties. Functional Digital Mock-up (FunctionalDMU) is a combination of traditional DMU with behavioral simulation in mechatronics. Enhancing DMU with functional aspects, considerably more insight in product properties can be gained. To enable FunctionalDMU two main tasks have to be solved: a) simulators in the areas of mechanics, electronics, and software simulation have to talk to each other (coupling) and b) the simulation results have to be visualized in an interactive DMU environment. In this paper we present an independent and open approach to a FunctionalDMU framework including co-simulation. Starting with proprietary and natively given behavior and geometric models (in formats like JT), we wrap the behavior models into SysML to enable data exchange on an agreed and standardized format. The native behavior models still are executed in the corresponding simulators. The simulators are linked to the FunctionalDMU framework using a wrapping approach. Currently we support simulators such as Matlab/Simulink, Dymola, Saber, Rhapsody, SimPack, ANSYS with our framework. During simulation a simulator coupling algorithm controls the simulation processes. A dedicated visualization environment enables the user to interact with the simulation, i.e., to send simulation stimuli, change parameters, observe the simulation run etc. This paper introduces the components of the FunctionalDMU framework and illustrates the approach with an application example.
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Long, Henry A., and Ting Wang. "Case Studies for Biomass/Coal Co-Gasification in IGCC Applications." In ASME 2011 Turbo Expo: Turbine Technical Conference and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/gt2011-45512.
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Employing biomass as a feedstock to generate fuels or power has the advantage of being carbon neutral or even becoming carbon negative, if carbon is captured and sequestrated. However, there are challenges facing the effective utilization of biomass wastes: (a) biomass supply is limited and varies with the seasons, (b) biomass density is low and expensive for long-distance transportation, and (c) due to a limited supply of feedstock, biomass plants are usually small, which results in higher capital and production costs. Considering these challenges, it is more economically attractive and less technically challenging to co-combust or co-gasify biomass wastes with coal. This paper focuses on discussing issues associated with coal/biomass co-gasification as well as an investigation into the effect of adding different amounts of biomass up to 50% (wt.) on a 250MW IGCC plant’s performance, although a smaller plant of 75MW using 100% biomass is also included for comparison. The Siemens SGT6-6000G and Alstom GT8C2 gas turbines are used in the larger and smaller plants respectively. The results show the plant’s efficiency increases first as 10% biomass is added; then decreases as the biomass is increased to 30%; and increases again once the biomass reaches 50%. The variation of efficiency is minor, only within one percentage between 38% and 39%. The advantage of adding biomass can be seen from the almost proportional reductions of SOx, ash, energy for H2S removal, water for scrubber, and the effective CO2 emission. The effective CO2 is calculated by subtracting the neutral CO2 that is theoretically produced by burning the added biomass.
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Zhyltsova, Y. V., E. A. Sinevich, N. S. Smolnik, and P. R. Khilimonchyk. "ANALYSIS OF MICROELEMENTOSIS FORMATION FACTORS OF ZHODINO’ PRIMARY SCHOOL AGE CHILDREN." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2021. http://dx.doi.org/10.46646/sakh-2021-2-45-48.
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The work analyzes the factors influencing the development of excess, deficiency, or imbalance of macro-and microelements in the organism of 7-10-year-old children living in a large industrial city. Based on a questionnaire survey, it was revealed that the development of natural exogenous microelementosis associated with a lack of B, Mo, Zn, Mn, Se in the soil is subject to more than 80 % of respondents, iodine deficiency - 30 %. The risks of acquiring technogenic microelementosis by the population are possible as a result of the increased content of Pb, Cu, Sn, Cr, Co in the soil, Ni, Sn, Zr, Cr, Cu, Co in the production of meadow and agrophytocenoses, Fe and Mn in the water. More than 40 % of children consume tap water without preliminary preparation, 4 % of families periodically use water from wells. The development of natural endogenous microelementosis is possible in 12-58 % cases, iatrogenic microelementosis - in more than 6 % cases.
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Stepanova, Evgeniya M., and Elena A. Lugovaya. "BIOELEMENT CORRELATIONS IN BIOLOGICAL ENVIRONMENTS OF INDIVIDUALS WITH DIFFERENT LEVELS OF PHYSICAL ACTIVITY." In 22nd SGEM International Multidisciplinary Scientific GeoConference 2022. STEF92 Technology, 2022. http://dx.doi.org/10.5593/sgem2022/5.1/s20.009.
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In order to emphasize the distribution of chemical elements (ChE) in biological environments, we determined hair and blood chemical concentrations in forty-seven male volunteers aged 19-23, who were divided into two groups: athlete and control. Atomic emission analysis showed stable deficiencies, which is commonly characteristic of northerners (I, Co, Mg, Se, Ca). More correlations existed in hair samples than in blood, which again proves that blood is a more dynamic environment of the body while hair is a better substrate for assessing either element deficiency or excess. When creating correlations, we could trace a number of features of elemental bonds in the hair and whole blood samples as they form with the same people. The correlation structure proved to be different in individuals who experienced regular exercising and those not involved in doing sports. The following relations were common in structures of the hair element systems shown by both athlete and control subjects: Al/Pb, Al/Sn, As/Cr, As/Li, As/Pb, As/Sn, B/Li, B/Na, B/Pb, Ca/Mg, Ca/Mn, Cd/Na, Cd/Ni, Cd/Pb, Cd/Sn, Cr/Ni, Cr/Pb, Cr/Sn, Fe/Mn, Fe/Zn, Li/Na, Li/Pb, Mg/Mn, Mg/P, Na/Pb, Na/V, Ni/Pb, Ni/Sn, Pb/V.
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Ismail, Rabah Mahmoud Ahmad, R. Rathinam, Marwa Al-Jamal, Sathish Kumar Ramachandran, Hashem Al-Mattarneh, Bhasker Pant, and Pandurang Y. Patil. "Mn-BIM Based Photo-Catalytic Degradation of Hazardous Industrial Organic Pollutants in Fresh Water." In International Conference on Recent Advancements in Biomedical Engineering. Switzerland: Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-1c4w1k.
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A simple chemical co-precipitation approach was used to produce in situ nanocomposites based on Mn-BIM, and the results were promising. It is possible to increase the photocatalytic degradation efficiency. The morphology of the nanocomposites is investigated using X-ray diffraction data and the structural features of the nanocomposites are investigated using electron microscopy. Mn-BIM is a nanoparticle with an average size of 50 nm. In order to determine their photo-catalytic activity, researchers investigated nanocomposites produced from industrial waste dyes rhodamine-B. Following 90 minutes in direct sunshine, the photo-degradation of these dyes occurs, with a photo-degradation rate of more than 90 percent. To evaluate whether nanocomposite materials have the ability to photodegrade dyes, tests have been carried out. The rate-limiting stepwise de-ethylation process for the degradation of rhodamine-B dye has been proposed as the mechanism of degradation.
Reports on the topic "E.B. Moore and Co"
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Friedmann, Michael, Charles J. Arntzen, and Hugh S. Mason. Expression of ETEC Enterotoxin in Tomato Fruit and Development of a Prototype Transgenic Tomato for Dissemination as an Oral Vaccine in Developing Countries. United States Department of Agriculture, March 2003. http://dx.doi.org/10.32747/2003.7585203.bard.
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The broad objective of the project was to develop a feasible approach to combat diarrheal disease caused by ETEC through the development of a low-cost oral immunogen in tomato fruit, expressed in the context of a prototype tomato that would answer the shortcomings of plant oral vaccines, especially in terms of produce handling and control of gene escape. Specifically, the goals for Boyce Thompson Institute (BTI) on this project were to develop transgenic tomato lines that express the enterotoxigenic E. coli (ETEC) heat-labile enterotoxin (LT) subunits A and/or B for use in oral edible vaccines, and to optimize expression and assembly of these antigens in tomato fruits.LT-B is a useful vaccine antigen against ETEC disease, since antibodies against LT-B can prevent binding and delivery of the holotoxinLT. Mutant forms of the toxic LT-A subunit that have reduced toxicity can be co-expressed and assembled with LT-Bpentamers to form mutant LT (mLT) complexes that could be used as mucosaladjuvants for other oral vaccines. Work on the project is continuing at Arizona State University, after Dr. Mason moved there in August 2002. A number of approaches were taken to ensure the expression of both subunits and bring about their assembly inside the transgenic fruits. Initially, expression was driven by the fruit-specific E-8 promoter for LT-B and the constitutive CaMV 35S promoter for LT-A(K63). While LT-B accumulated up to 7 µg per gram ripe fruit, assembled LT-K63 was only 1 µg per gram. Since promoter activities for the two genes likely differed in cell type and developmental stage specificity, the ratios of A and B subunits was not optimal for efficient assembly in all cells. In order to maximize the chance of assembly of mLT in fruit, we focused on constructs in which both genes are driven by the same promoter. These included co-expression plasmids using the 35S promoter for both, while switching to attenuated mLTs (LT-R72 and LT-G192) that have shown greater potential for oral adjuvanticity than the initial LT-K63, and thus are better candidates for a plant-derived adjuvant. Other, more novel approaches were then attempted, including several new vectors using the tomato fruit-specific E8 promoter driving expression of both LT-B and mutant LT-A, as well as a dicistronic construct for co-expression of both LT-B and mutant LT-A genes from a single promoter, and a geminivirusreplicon construct. We describe in the Appendix the results obtained in transgenic tomato lines transformed with these constructs. Overall, each contributed to enhanced expression levels, but the assembly itself of the holotoxin to high levels was not observed in the fruit tissues. The Israeli lab’s specific objective was to develop transgenic tomato lines expressing the LTholotoxin antigen bearing attributes to prevent gene escape (male sterility and orange fruit color) and to improve the dissemination of the oral vaccine (long shelf-life tomato cherry fruit or tomato processing background). Breeding lines bearing a number of attributes to prevent gene escape were developed by combining material and backcrossing either to a tomato cherry background, or two different processing backgrounds. Concomitantly, (these lines can be utilized for the creation of any future oral vaccine or other therapeutic-expressing tomato, either by crosses or transformation), the lines were crossed to the holotoxin-expressing tomatoes received from the United States, and this transgenic material was also incorporated into the backcrossing programs. To date, we have finalized the preparation of the cherry tomato material, both non-transgenic (bearing all the desired attributes), and transgenic, expressing the holotoxin. The level of expression of LT-B in the cherry fruits was comparable to the original transgenic tomatoes. Since it was not higher, this would necessitate the consumption of more fruits to reach a desired dose. A final backcross has been made for both the non-transgenic and the transgenic material in the processing lines. Auxin sprays resulted in high percentages of fruit set, but the processing genotypes gave many puffed fruits.
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Barnhoorn, Anniek. Comparing Responses to Climate-related Security Risks Among the EU, NATO and the OSCE. Stockholm International Peace Research Institute, April 2023. http://dx.doi.org/10.55163/rdou1271.
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This SIPRI Policy Report compares responses to climate-related security risks by the European Union (EU), the North Atlantic Treaty Organization (NATO) and the Organization for Security and Co-operation in Europe (OSCE). All three organizations have formulated ambitious policies in this area in recent years. However, while they have come a long way in raising the interlinkages between climate, peace and security on their agendas, more is required to achieve their various ambitions. This paper recommends three ways forward for policymakers: (a) enhance cooperation between relevant European regional organizations; (b) increase leadership from member states, including through dedicated bodies; and (c) strengthen financial instruments aimed at supporting responses to climate-related security risks.
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Hadjipanayis, George C. High Performance (Nd,Pr)-(Fe,Co)-B Magnets. Fort Belvoir, VA: Defense Technical Information Center, May 2002. http://dx.doi.org/10.21236/ada402253.
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Fulmer, P., J. Kim, A. Manthiram, and J. M. Sanchez. Chemical synthesis of magnetic Fe-B and Fe-Co-B particles and chains. Office of Scientific and Technical Information (OSTI), April 1999. http://dx.doi.org/10.2172/334201.
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Ghanim, Murad, Joe Cicero, Judith K. Brown, and Henryk Czosnek. Dissection of Whitefly-geminivirus Interactions at the Transcriptomic, Proteomic and Cellular Levels. United States Department of Agriculture, February 2010. http://dx.doi.org/10.32747/2010.7592654.bard.
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Our project focuses on gene expression and proteomics of the whitefly Bemisia tabaci (Gennadius) species complex in relation to the internal anatomy and localization of expressed genes and virions in the whitefly vector, which poses a major constraint to vegetable and fiber production in Israel and the USA. While many biological parameters are known for begomovirus transmission, nothing is known about vector proteins involved in the specific interactions between begomoviruses and their whitefly vectors. Identifying such proteins is expected to lead to the design of novel control methods that interfere with whitefly-mediated begomovirus transmission. The project objectives were to: 1) Perform gene expression analyses using microarrays to study the response of whiteflies (B, Q and A biotypes) to the acquisition of begomoviruses (Tomato yellow leaf curl (TYLCV) and Squash leaf curl (SLCV). 2) Construct a whitefly proteome from whole whiteflies and dissected organs after begomovirus acquisition. 3) Validate gene expression by q-RTPCR and sub-cellular localization of candidate ESTs identified in microarray and proteomic analyses. 4) Verify functionality of candidate ESTs using an RNAi approach, and to link these datasets to overall functional whitefly anatomical studies. During the first and second years biological experiments with TYLCV and SLCV acquisition and transmission were completed to verify the suitable parameters for sample collection for microarray experiments. The parameters were generally found to be similar to previously published results by our groups and others. Samples from whole whiteflies and midguts of the B, A and Q biotypes that acquired TYLCV and SLCV were collected in both the US and Israel and hybridized to B. tabaci microarray. The data we analyzed, candidate genes that respond to both viruses in the three tested biotypes were identified and their expression that included quantitative real-time PCR and co-localization was verified for HSP70 by the Israeli group. In addition, experiments were undertaken to employ in situ hybridization to localize several candidate genes (in progress) using an oligonucleotide probe to the primary endosymbiont as a positive control. A proteome and corresponding transcriptome to enable more effective protein identification of adult whiteflies was constructed by the US group. Further validation of the transmission route of begomoviruses, mainly SLCV and the involvement of the digestive and salivary systems was investigated (Cicero and Brown). Due to time and budget constraints the RNAi-mediated silencing objective to verify gene function was not accomplished as anticipated. HSP70, a strong candidate protein that showed over-expression after TYLCV and SLCV acquisition and retention by B. tabaci, and co-localization with TYLCV in the midgut, was further studies. Besides this protein, our joint research resulted in the identification of many intriguing candidate genes and proteins that will be followed up by additional experiments during our future research. To identify these proteins it was necessary to increase the number and breadth of whitefly ESTs substantially and so whitefly cDNAs from various libraries made during the project were sequenced (Sanger, 454). As a result, the proteome annotation (ID) was far more successful than in the initial attempt to identify proteins using Uniprot or translated insect ESTs from public databases. The extent of homology shared by insects in different orders was surprisingly low, underscoring the imperative need for genome and transcriptome sequencing of homopteran insects. Having increased the number of EST from the original usable 5500 generated several years ago to >600,000 (this project+NCBI data mining), we have identified about one fifth of the whitefly proteome using these new resources. Also we have created a database that links all identified whitefly proteins to the PAVEdb-ESTs in the database, resulting in a useful dataset to which additional ESTS will be added. We are optimistic about the prospect of linking the proteome ID results to the transcriptome database to enable our own and other labs the opportunity to functionally annotate not only genes and proteins involved in our area of interest (whitefly mediated transmission) but for the plethora of other functionalities that will emerge from mining and functionally annotating other key genes and gene families in whitefly metabolism, development, among others. This joint grant has resulted in the identification of numerous candidate proteins involved in begomovirus transmission by B. tabaci. A next major step will be to capitalize on validated genes/proteins to develop approaches to interfere with the virus transmission.
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Shen, Y., A. Higgins, C. Chen, and S. Liu. Hybrid R-Fe-B/R-Co Magnets with Improved Thermal Stability. Fort Belvoir, VA: Defense Technical Information Center, December 2009. http://dx.doi.org/10.21236/ada519522.
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Valverde, Alvaro. Information and communication technologies for improving investment readiness of small and medium agribusinesses. Commercial Agriculture for Smallholders and Agribusiness (CASA), 2020. http://dx.doi.org/10.1079/20240191164.
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Information and communication technologies (ICTs) are increasingly seen as an enabler to improve and promote efficiencies in global food market systems, and the high penetration rate of mobile phones is playing a catalytic role in developing countries. Mobile-based agriculture-value-added services (agri-VAS) aim to mitigate the information, financial and market access gaps faced by smallholder farmers and agribusinesses in developing countries. Over the last two decades, the number and variety of agri-VAS has been continuously increasing, and their landscape has been evolving. However, many agri-VAS never reach financial sustainability or scale and are discontinued after a few years. Increasing efforts are being made to map the landscape of agri-VAS targeted at smallholder farmers across Africa and Asia. However, insufficient attention has been paid to exploring successful agri-VAS that have small and medium (SME) agribusinesses as their main clients and that source from smallholder farmers. Areas with potential for further study include the following: (a) agribusinesses operating in value chains that are digitized by others (e.g. mobile network operators); (b) agribusinesses that are developing and deploying agri-VAS in-house; (c) agribusinesses using services provided by third-party agri-VAS providers within their value chains; and (d) agribusinesses that develop partnerships with agri-VAS providers to co-develop solutions. This study aims to address the following question: What are the factors behind successful deployment of mobile technologies to improve agribusiness productivity and investment readiness? It aims to analyse agri-VAS that have SME agribusinesses as their main clients, as they are more likely to positively impact the investment readiness of SME agribusinesses than agri-VAS with smallholder farmers as their only clients, which are also the most evaluated type of agri-VAS. The study consists of a combination of secondary and primary research, resulting in: (a) a set of investment-policy and service-design recommendations, based on high-impact, sustainable agribusiness-focused VAS; (b) recommendations on how to improve the body of impact evidence; and (c) the identification of investment opportunities at the agribusiness and agri-VAS levels.
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Needham, Glenn R., Uri Gerson, Gloria DeGrandi-Hoffman, D. Samatero, J. Yoder, and William Bruce. Integrated Management of Tracheal Mite, Acarapis woodi, and of Varroa Mite, Varroa jacobsoni, Major Pests of Honey Bees. United States Department of Agriculture, March 2000. http://dx.doi.org/10.32747/2000.7573068.bard.
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Objectives: The Israeli work plan regarding HBTM included: (a) producing a better diagnostic method; (b) following infestations during the season and evaluating damage to resistant bees and, (c) controlling HBTM by conventional means under local conditions. For varroa our plans to try novel control (e.g. oil novel control (e.g. oil patties & essential oils) were initially delayed by very low pest populations, then disrupted by the emergence of fluvalinate resistance. We monitored the spread of resistance to understand it better, and analyzed an underlying biochemical resistance mechanism in varroa. The US work plan focused on novel management methods for both mites with an emphasis on reducing use of traditional insecticides due to resistance and contamination issues. Objectives were: (a) evaluating plant essential oils for varroa control; (b) exploring the vulnerability of varroa to desiccation for their management; and (c) looking for biological variation in HBTM that could explain virulence variability between colonies. Although the initial PI at the USDA Beltsville Bee Lab, W.A. Bruce, retired during the project we made significant strides especially on varroa water balance. Subcontracts were performed by Yoder (Illinois College) on varroa water balance and DeGrandi-Hoffman (USDA) who evaluated plant essential oils for their potential to control varroa. We devised an IPM strategy for mite control i the U.S. Background: Mites that parasitize honey bees are a global problem. They are threatening the survival of managed and feral bees, the well-being of commercial/hobby beekeeping, and due to pollination, the future of some agricultural commodities is threatened. Specific economic consequences of these mites are that: (a) apiculture/breeder business are failing; (b) fewer colonies exist; (c) demand and cost for hive leasing are growing; (d) incidences of bee pathogens are increasing; and, (e) there are ore problems with commercial-reared bees. As a reflection of the continued significance f bee mites, a mite book is now in press (Webster & delaplane, 2000); and the 2nd International Conference on Africanized Honey Bees and Bee Mites is scheduled (April, 2000, Arizona). The first such conference was at OSU (1987, GRN was co-organizer). The major challenge is controlling two very different mites within a colony while not adversely impacting the hive. Colony management practices vary, as do the laws dictating acaricide use. Our basic postulates were that: (a) both mites are of economic importance with moderate to high infestations but not at low rates and, (b) once established they will not be eradicated. A novel strategy was devised that deals with the pests concomitantly by maintaining populations at low levels, without unnecessary recourse to synthetic acaricides. Major Conclusions, Solutions, Achievements: A major recent revelation is that there are several species of "Varroa jacobsoni" (Anderson & Trueman 1999). Work on control, resistance, population dynamics, and virulence awaits knowing whether this is a problem. In the U.S. there was no difference between varroa from three locales in terms of water balance parameters (AZ, MN & PA), which bodes well for our work to date. Winter varroa (U.S.) were more prone to desiccation than during other seasons. Varroa sensitivity to desiccation has important implications for improving IPM. Several botanicals showed some promise for varroa control (thymol & origanum). Unfortunately there is varroa resistance to Apistan in Israel but a resistance mechanism was detected for the first time. The Israel team also has a new method for HBTM diagnosis. Annual tracheal mite population trends in Israel were characterized, which will help in targeting treatment. Effects of HBTM on honey yields were shown. HBTM control by Amitraz was demonstrated for at least 6 months. Showing partial resistance by Buckfast bees to HBTM will be an important IPM tactic in Israel and U.S.
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Alderman, J., P. K. Job, and J. Puhl. Irradiation of Nd-Fe-B permanent magnets with APS bending magnet x-rays and {sup 60}Co {gamma}-rays. Office of Scientific and Technical Information (OSTI), September 2000. http://dx.doi.org/10.2172/764212.
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Edmonds, J. A., J. M. Reilly, R. H. Gardner, and A. Brenkert. Uncertainty in future global energy use and fossil fuel CO{sub 2} emissions 1975 to 2075: Appendices A--B. Office of Scientific and Technical Information (OSTI), December 1985. http://dx.doi.org/10.2172/537320.
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