Journal articles: 'Dust mite allergy'

1

KS, Goutam. "Dust Mite Allergy and Lifestyle - Indian Perspective." International Journal of Zoology and Animal Biology 1, no. 4 (2016): 1–2. http://dx.doi.org/10.23880/izab-16000119.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Jacquet, Alain. "Innate Immune Responses in House Dust Mite Allergy." ISRN Allergy 2013 (February 28, 2013): 1–18. http://dx.doi.org/10.1155/2013/735031.

Full text

Abstract:

Sensitizations to house dust mites (HDM) trigger strong exacerbated allergen-induced inflammation of the skin and airways mucosa from atopic subjects resulting in atopic dermatitis as well as allergic rhinitis and asthma. Initially, the Th2-biased HDM allergic response was considered to be mediated only by allergen B- and T-cell epitopes to promote allergen-specific IgE production as well as IL-4, IL-5, and IL-13 to recruit inflammatory cells. But this general molecular model of HDM allergenicity must be revisited as a growing literature suggests that stimulations of innate immune activation pathways by HDM allergens offer new answers to the following question: what makes an HDM allergen an allergen? Indeed, HDM is a carrier not only for allergenic proteins but also microbial adjuvant compounds, both of which are able to stimulate innate signaling pathways leading to allergy. This paper will describe the multiple ways used by HDM allergens together with microbial compounds to control the initiation of the allergic response through engagement of innate immunity.

APA, Harvard, Vancouver, ISO, and other styles

3

Mosbech, H. "House Dust Mite Allergy." Allergy 40, no. 2 (February 1985): 81–91. http://dx.doi.org/10.1111/j.1398-9995.1985.tb02665.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Milovanovic, Katarina, Lidija Burazer, Olga Vuckovic, Marina Atanaskovic-Markovic, Tanja Cirkovic-Velickovic, Ratko Jankov, and Marija Gavrovic-Jankulovic. "Isolation and characterization of the 68 kD allergen from house dust mite Dermatophagoides pteronyssinus." Journal of the Serbian Chemical Society 74, no. 5 (2009): 513–22. http://dx.doi.org/10.2298/jsc0905513m.

Full text

Abstract:

House dust mites (HDM) represent a major source of allergens, contributing to the increasing incidence of type I hypersensitivity disease worldwide. Over 30 different IgE-binding proteins from the HDM extract were detected. Although group 1 and 2 have been identified as major allergens, due to the safety and efficacy of allergy diagnosis and immunotherapy, there is a need to carefully evaluate the clinical relevance of other allergens present in the HDM extract. In regard to this, a high molecular mass allergen of about 68 kD was purified from the HDM extract using a combination of gel permeation chromatography and reversed-phase chromatography. The IgG and IgE reactivity of the purified protein were preserved during the purification process, as confirmed by Western blot analysis with polyclonal rabbit antibodies and dot blot analysis with a pool of sera from subjects with house dust mite allergy, respectively. In addition, the IgE reactivity was confirmed using ELISA testing with nine patient sera. The biological potency of the 68 kD allergen was confirmed by skin prick testing in five allergic subjects, suggesting that the high molecular mass allergen is a good candidate for component-resolved diagnosis of house dust mite allergy and eventual therapeutic treatment.

APA, Harvard, Vancouver, ISO, and other styles

5

Nanda, Manpreet S., and Rama Devi. "Seasonal variation of allergy profile of patients visiting a tertiary care hospital in hilly areas of Himachal Pradesh." International Journal Of Community Medicine And Public Health 6, no. 1 (December 24, 2018): 146. http://dx.doi.org/10.18203/2394-6040.ijcmph20185079.

Full text

Abstract:

Background: Allergic diseases are very common and are caused by allergen whose role varies according to climate changes. Not many studies are available regarding the same in our region. Skin prick test is a diagnostic procedure for allergy testing. The aim of the present study was to find out the seasonal variation of different allergies in our region.Methods: A total of 686 patients with allergic complaints were assessed for age and sex distribution, seasonal variation of number of allergy patients and seasonal variation of patient symptoms. 608 patients who gave consent and were found fit for skin prick tests underwent the tests and were analysed for allergy profile of the patients in different seasons.Results: The majority of patients were females and of younger age group. The majority of the patients had nasal symptoms and these symptoms were more in summer and rainy season during which pine mix and grass pollen were common allergens. Pulmonary symptoms were maximum in winters with dust mite and moulds being the common allergens. Dust mite was overall the most common allergen involved. Sensitization to allergens was less in winter months.Conclusions: This study focussed on seasonal variation of allergies and found pine mix and grass pollens to be major cause of nasal allergy and dust mite and mould mix to mainly cause pulmonary symptoms.

APA, Harvard, Vancouver, ISO, and other styles

6

Burazer, Lidija, Katarina Milovanovic, Tanja Cirkovic-Velickovic, and Marija Gavrovic-Jankulovic. "Stability evaluation of house dust mite vaccines for sublingual immunotherapy." Journal of the Serbian Chemical Society 75, no. 1 (2010): 19–26. http://dx.doi.org/10.2298/jsc1001019b.

Full text

Abstract:

Allergen-specific immunotherapy with house dust mite (HDM) allergen extracts can effectively alleviate the symptoms of allergic rhinitis and asthma. The efficacy of the immunotherapeutic treatment is highly dependent on the quality of house dust mite vaccines. This study was performed to assess the stability of house dust mite allergen vaccines prepared for sublingual immunotherapy. Lyophilized Dermatophagoides pteronyssinus (Dpt) mite bodies were the starting material for the production of sublingual vaccines in four therapeutic concentrations. The stability of the extract for vaccine production, which was stored below 4 ?C for one month, showed consistence in the protein profile in SDS PAGE. ELISA-inhibition showed that the potencies of Dpt vaccines during a 12 month period were to 65-80 % preserved at all analyzed therapeutic concentrations. This study showed that glycerinated Dpt vaccines stored at 4?C preserved their IgE-binding potential during a 12 month period, implying their suitability for sublingual immunotherapeutic treatment of HDM allergy.

APA, Harvard, Vancouver, ISO, and other styles

7

Terada, Tetsuya, and Ryo Kawata. "Early Intervention is Important to Prevent Sensitization to New Allergens." Medical Sciences 6, no. 4 (December 11, 2018): 114. http://dx.doi.org/10.3390/medsci6040114.

Full text

Abstract:

We review current management for allergic rhinitis and possible new treatments for this condition. Management of allergic rhinitis includes promotion of protective factors, avoidance of allergens, and possibly immunotherapy. In recent years, the incidence of allergic rhinitis has increased in many countries. Early intervention at different stages is an important part of management. Allergic disease in infants has been described as the allergic march, commencing with atopic dermatitis accompanied by infantile asthma and progressing to perennial allergic rhinitis induced by house dust mite allergy. In order to prevent polysensitization, allergen-specific immunotherapy should probably be initiated at an earlier age, especially in children with rhinitis who show monosensitization to house dust mite antigens.

APA, Harvard, Vancouver, ISO, and other styles

8

&NA;. "House dust mite allergy vaccine." Reactions Weekly &NA;, no. 1197 (April 2008): 23. http://dx.doi.org/10.2165/00128415-200811970-00081.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

&NA;. "House dust mite allergy vaccine." Reactions Weekly &NA;, no. 1257 (June 2009): 23–24. http://dx.doi.org/10.2165/00128415-200912570-00072.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Voelker, Rebecca. "Relief for Dust Mite Allergy." JAMA 317, no. 15 (April 18, 2017): 1518. http://dx.doi.org/10.1001/jama.2017.3630.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

&NA;. "House dust mite allergy immunotherapy." Reactions Weekly &NA;, no. 1361 (July 2011): 25. http://dx.doi.org/10.2165/00128415-201113610-00087.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

&NA;. "House dust mite allergy immunotherapy." Reactions Weekly &NA;, no. 1391 (March 2012): 24. http://dx.doi.org/10.2165/00128415-201213910-00087.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Eguiluz-Gracia, Ibon, Francisca Palomares, Maria Salas, Almudena Testera-Montes, Adriana Ariza, Ignacio Davila, Joan Bartra, Cristobalina Mayorga, Maria Jose Torres, and Carmen Rondon. "Precision Medicine in House Dust Mite-Driven Allergic Asthma." Journal of Clinical Medicine 9, no. 12 (November 26, 2020): 3827. http://dx.doi.org/10.3390/jcm9123827.

Full text

Abstract:

House dust mites (HDMs) are the allergenic sources most frequently involved in airway allergy. Nevertheless, not every sensitized patient develops respiratory symptoms upon exposure to HDM, and there is a clinical need to differentiate allergic asthmatics (AAs) from atopic non-allergic asthmatics with HDM sensitization. This differentiation sometimes requires in vivo provocations like the bronchial allergen challenge (BAC). Interestingly, recent data demonstrate that non-atopic patients with asthma can also develop positive BAC results. This novel phenotype has been termed local allergic asthma (LAA). The interest in identifying the allergic triggers of asthma resides in the possibility of administering allergen immunotherapy (AIT). AIT is a disease-modifying intervention, the clinical benefit of which persists after therapy discontinuation. Recently, new modalities of sublingual tablets of HDM immunotherapy registered as pharmaceutical products (HDM-SLIT tablets) have become commercially available. HDM-SLIT tablets have demonstrated a robust effect over critical asthma parameters (dose of inhaled corticosteroids, exacerbations, and safety), thus being recommended by international guidelines for patients with HDM-driven AA. In this review, we will summarize the current knowledge on the phenotype and endotype of HDM-driven AA, and LAA, address the difficulties for BAC implementation in the clinic, and discuss the effects of AIT in AA and LAA.

APA, Harvard, Vancouver, ISO, and other styles

14

Soegiarto, Gatot, David Kurnia, Chairul Effendi, and Putu Gedhe Konthen. "CETIRIZINE SUPPRESSION TO SKIN PRICK TEST RESULTS IN ATOPIC ALLERGY PATIENTS." Folia Medica Indonesiana 53, no. 2 (November 3, 2017): 152. http://dx.doi.org/10.20473/fmi.v53i2.6432.

Full text

Abstract:

This study was done to determine the suppression index of Cetirizine to the skin prick test results to obtain a correction constant or factor that can be used to assess the results of the skin prick test in patients who cannot stop the use of antihistamines (Cetirizine). This pre and post test study design clinical trial involved 22 atopic allergy patients who seek medical treatment at the Allergy and Immunology Outpatient Clinic Dr. Soetomo Hospital. Skin prick tests were done twice (SPT1 and SPT2) using house dust mite allergen extract to all study subjecs. The first (SPT1) were done after washout of all antihistamine for 1 week prior the test. All study subjects were then given Cetirizine 10 mg once daily for 5 days and on day 6 we performed the second test (SPT2). Cetirizine suppresion index and correction factor were calculated by comparing the wheal area of SPT1 and SPT2. All 22 study subjects (6 males and 16 females) were sensitized to house dust mite allergen. Mean serum total IgE levels were 176.42 + 352.5 IU/dL. Mean wheal area generated by the positive control (histamine 1 mg/mL) in SPT1 was 7.53 + 7.31 mm2, and in SPT2 was 1.08 + 1.46 mm2. Mean wheal area generated by house dust mite allergen in SPT1 was 43.57 + 36 mm2, and in SPT2 was 10.28 + 8.47 mm2. Cetirizine suppression index for positive controls (histamine 10 mg/mL) was 94.63 + 7.90% (p=0.000), while the Cetirizine suppression index for house dust mite allergen is 72.31 + 13.96% (p=0.000). There was no significant influence of serum total IgE levels to Cetirizine suppression index (p=0.381). The correction constant based on the calculation was 1.9. In conclusion, Cetirizine suppression index to the mean wheals area generated by house dust mite allergen was 72.31% and the correction constant was 1.9. In allergic patients who cannot stop their antihistamine drugs, Cetirizine 10 mg once daily can be used as a replacement and they still be able to undergo skin prick tests. The actual wheal diameter (or area) of the skin prick test results can be calculated by multiplying the measured wheal diameter (or area) under the Cetirizine administration with the correction constant.

APA, Harvard, Vancouver, ISO, and other styles

15

Song, Y., J. Long, T. Wang, J. Xie, M. Wang, and G. Tan. "Long-term efficacy of standardised specific subcutaneous immunotherapy in children with persistent allergic rhinitis due to multiple allergens including house dust mites." Journal of Laryngology & Otology 132, no. 3 (January 28, 2018): 230–35. http://dx.doi.org/10.1017/s0022215117002547.

Full text

Abstract:

AbstractObjectives:To observe the five-year efficacy of standardised specific subcutaneous immunotherapy for house dust mite allergy in monosensitised and polysensitised children with persistent allergic rhinitis.Methods:From January 2007 to August 2009, 236 children with persistent allergic rhinitis were divided into 2 groups: 1 group received standardised specific subcutaneous immunotherapy using house dust mite extract; the other received pharmacotherapy with intranasal corticosteroids and oral antihistamines. A total of 193 patients (106 in the immunotherapy group and 87 in the pharmacotherapy group) completed treatment. Scores for symptoms, total medication and quality of life were evaluated.Results:The subcutaneous immunotherapy group demonstrated a significant reduction in visual analogue scale scores, Rhinoconjunctivitis Quality of Life Questionnaire scores and total medication scores (p < 0.05) compared with the pharmacotherapy group. No significant differences in the visual analogue scale and Rhinoconjunctivitis Quality of Life Questionnaire scores were found between the polysensitised and monosensitised subgroups (p > 0.05). No serious adverse events occurred.Conclusion:Standardised subcutaneous immunotherapy has long-term efficacy for children with persistent allergic rhinitis. Single-allergen subcutaneous immunotherapy was appropriate for allergic rhinitis caused by multiple allergens, including house dust mites, in the paediatric population.

APA, Harvard, Vancouver, ISO, and other styles

16

Nelson, Harold S. "Immunotherapy for house-dust mite allergy." Allergy and Asthma Proceedings 39, no. 4 (July 1, 2018): 264–72. http://dx.doi.org/10.2500/aap.2018.39.4145.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

&NA;. "House dust mite allergy vaccine overdose." Reactions Weekly &NA;, no. 1184 (January 2008): 21. http://dx.doi.org/10.2165/00128415-200811840-00066.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Yang, Lin, and Rongfei Zhu. "Immunotherapy of house dust mite allergy." Human Vaccines & Immunotherapeutics 13, no. 10 (October 3, 2017): 2390–96. http://dx.doi.org/10.1080/21645515.2017.1364823.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Korsgaard, J., and M. Iversen. "Epidemiology of house dust mite allergy." Allergy 46, s11 (January 1991): 14–18. http://dx.doi.org/10.1111/j.1398-9995.1991.tb00643.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Heinig, J. H., H. Mosbech, and L. Haugaard. "Diagnosis of house dust mite allergy." Allergy 46, s11 (January 1991): 19–22. http://dx.doi.org/10.1111/j.1398-9995.1991.tb00644.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Tharr, Dawn. "Case Studies: House Dust Mite Allergy." Applied Occupational and Environmental Hygiene 6, no. 2 (February 1991): 94–96. http://dx.doi.org/10.1080/1047322x.1991.10387839.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Platts-Mills, Thomas A. E., E. Bruce Mitchell, Martin D. Chapman, and Peter W. Heymann. "Dust Mite Allergy: Its Clinical Significance." Hospital Practice 22, no. 9 (September 15, 1987): 91–100. http://dx.doi.org/10.1080/21548331.1987.11703307.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Yi, Fong, Lynette Shek, Nge Cheong, Kaw Chua, and Bee Lee. "Dust Mite Allergy in East Asia." Allergy & Clinical Immunology International - Journal of the World Allergy Organization 16, no. 04 (2004): 150–54. http://dx.doi.org/10.1027/0838-1925.16.4.150.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

GK, Saha. "House Dust Mite Allergy in Kolkata Metropolis in Response to Change in Lifestyle." International Journal of Zoology and Animal Biology 2, no. 6 (2019): 1–8. http://dx.doi.org/10.23880/izab-16000189.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Kanbar, Chinar, Abdulameer Samad, and Ali Galleb. "Distribution of atopic conditions among attendants to specialized allergy center/ Kirkuk/ Iraqi." Al-Kitab Journal for Pure Sciences 3, no. 2 (October 17, 2020): 139–53. http://dx.doi.org/10.32441/kjps.03.02.p12.

Full text

Abstract:

Atopy is a syndrome characterized by genetic tendency to develop allergic diseases, such as asthma, allergic rhinitis and atopic dermatitis. The risk factors of atopic diseases can be placed in two categories, namely host and environmental factors. The host factors of allergy include genetics, race, gender, age… etc. The environmental factors include exposure to environmental pollution and allergens. To define the distribution of atopic conditions (asthma, allergic rhinitis and atopic dermatitis) according to age, residence and available skin prick test. This cross-sectional study included (100) patients, representing research sample. It was conducted in specialized allergy center in Kirkuk city during the period from first January .2016 to the end of December 2016 All patients included in this study were referred from primary health centers, complaining from signs and symptoms of atopic diseases. Depending on medical history and clinical examinations, the sample was classified into (3) groups (asthma, allergic rhinitis and atopic dermatitis). Skin prick test was used to identify patients allergy to house dust mite and pollen. Regarding the distribution of samples according to residence, most patients (about 91%) were from urban areas compared with (9%) of them were from rural areas. Also, it was found that the frequency of atopic diseases decreases by age advancement. The frequency distribution of asthma, allergic rhinitis and atopic dermatitis was 49%, 26% and 25%, respectively. The skin test data revealed the frequency of 2 aeroallergen mite and pollen in all patients under study. .Hence, 65% were sensitive to house dust mite, 26% to pollen and 9% to both mite and pollen In conclusion this study confirmed that most patients complaining from atopic disease were from urban area. Also, the frequency of atopic diseases decreased by age advancement. The most common atopic disease was asthma followed by allergic rhinitis and atopic dermatitis. Most patients were sensitive to house dust mite.

APA, Harvard, Vancouver, ISO, and other styles

26

Ohashi, Yoshihiro, Yoshiaki Nakai, Takemasa Nakagawa, Shoko Kihara, and Terumasa Miyamoto. "House Dust Mite-Specific Ige, Igg1, and Igg4 Antibodies in Patients with Perennial Rhinitis." Annals of Otology, Rhinology & Laryngology 96, no. 4 (July 1987): 434–37. http://dx.doi.org/10.1177/000348948709600417.

Full text

Abstract:

Serum samples were obtained from patients with house dust mite–sensitive nasal allergies before and 6 months after immunotherapy, and the level of immunoglobulin (Ig)E, IgG1, and IgG4 antibodies in those sera was determined by the enzyme-linked immunosorbent assay. The present data showed that the mite-specific IgG4 antibodies increased in patients who responded well to immunotherapy but not in those who responded poorly. It was suggested from the present study that IgG4 antibodies seem to act as “blocking antibodies” to reduce the allergic reaction in the target organ, and that an increase of allergen-specific IgG4 antibodies following immunotherapy can be of clinical benefit to patients suffering from mite-specific nasal allergy.

APA, Harvard, Vancouver, ISO, and other styles

27

Gazzinelli-Guimaraes, Pedro Henrique, Sasisekhar Bennuru, Rafael de Queiroz Prado, Alessandra Ricciardi, Joshua Sciurba, Jonah Kupritz, Matthew Moser, Olena Kamenyeva, and Thomas B. Nutman. "House dust mite sensitization drives cross-reactive immune responses to homologous helminth proteins." PLOS Pathogens 17, no. 3 (March 2, 2021): e1009337. http://dx.doi.org/10.1371/journal.ppat.1009337.

Full text

Abstract:

The establishment of type 2 responses driven by allergic sensitization prior to exposure to helminth parasites has demonstrated how tissue-specific responses can protect against migrating larval stages, but, as a consequence, allow for immune-mediated, parasite/allergy-associated morbidity. In this way, whether helminth cross-reacting allergen-specific antibodies are produced and play a role during the helminth infection, or exacerbate the allergic outcome awaits elucidation. Thus, the main objective of the study was to investigate whether house dust mite (HDM) sensitization triggers allergen-specific antibodies that interact with Ascaris antigens and mediate antibody-dependent deleterious effects on these parasites as well as, to assess the capacity of cross-reactive helminth proteins to trigger allergic inflammation in house dust mite presensitized mice. Here, we show that the sensitization with HDM-extract drives marked IgE and IgG1 antibody responses that cross-react with Ascaris larval antigens. Proteomic analysis of Ascaris larval antigens recognized by these HDM-specific antibodies identified Ascaris tropomyosin and enolase as the 2 major HDM homologues based on high sequence and structural similarity. Moreover, the helminth tropomyosin could drive Type-2 associated pulmonary inflammation similar to HDM following HDM tropomyosin sensitization. The HDM-triggered IgE cross-reactive antibodies were found to be functional as they mediated immediate hypersensitivity responses in skin testing. Finally, we demonstrated that HDM sensitization in either B cells or FcγRIII alpha-chain deficient mice indicated that the allergen driven cell-mediated larval killing is not antibody-dependent. Taken together, our data suggest that aeroallergen sensitization drives helminth reactive antibodies through molecular and structural similarity between HDM and Ascaris antigens suggesting that cross-reactive immune responses help drive allergic inflammation.

APA, Harvard, Vancouver, ISO, and other styles

28

Choudhari, Suhas Y., and Aravind B. Sangavi. "A clinical study of inhalant allergens in patients with allergic rhinitis." International Journal of Otorhinolaryngology and Head and Neck Surgery 3, no. 2 (March 25, 2017): 380. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20171197.

Full text

Abstract:

Background: The basis of diagnosis of allergy requires a good history and examination, however, the diagnosis cannot be confirmed on the basis of symptoms alone, because both allergic and non-allergic conditions can present with similar symptoms. Hence, allergy testing in the form of specific IgE (sIgE) measurement is an important aid in demonstrating both the presence and severity of such an allergy. The present study was undertaken to find out the common environmental allergens prevailing in Raichur causing allergic rhinitis, using carbohydrate cross reactive determinants (CCD), an in vitro test with high degree of sensitivity.Methods: The present prospective study was conducted among 30 patients with allergic rhinitis. A detailed general andENT examination were done, X-ray ofPNS, CT scan ofPNS, diagnostic nasal endoscopy and nasal smear examination for eosinophils, absolute eosinophil count and serum IgE levels using Euroimmun system of in vitro assay of specific IgE antibodies. Results: Allergy to dust mite, D. faranie, corn, carnation flower, sunflower, sheep wool and straw dust were the most frequent allergens causing allergic symptoms among patients in Raichur area. Total serum IgE was elevated in all the patients, 60% were allergic to dust mite as found by anti CCD specific IgE.Conclusions: Antibodies to dust mite D. faranie, rye, T. mothy grass was the commonest finding. Identification of inhalant allergens is an important factor in prevention and treatment of allergic rhinitis.

APA, Harvard, Vancouver, ISO, and other styles

29

Acevedo, Nathalie, Josefina Zakzuk, and Luis Caraballo. "House Dust Mite Allergy Under Changing Environments." Allergy, Asthma & Immunology Research 11, no. 4 (2019): 450. http://dx.doi.org/10.4168/aair.2019.11.4.450.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Mamikoglu, Bulent. "Headache and Dizziness and Dust Mite Allergy." Laryngoscope 121, S5 (2011): S254. http://dx.doi.org/10.1002/lary.22205.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Kaulsay, R. S., P.P, Y. Yeow, L. Rampal, and I. Hidayah. "House Dust Mite Allergy causing Otitis Externa." Journal of Allergy and Clinical Immunology 117, no. 2 (February 2006): S168. http://dx.doi.org/10.1016/j.jaci.2005.12.671.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Charpin, Denis. "Climate change and house-dust mite allergy." Journal of Climate Change and Health 2 (May 2021): 100012. http://dx.doi.org/10.1016/j.joclim.2021.100012.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Singh, Pramila, Mary Daniels, Darrell W. Winsett, Judy Richards, Donald Doerfler, Gary Hatch, Kenneth B. Adler, and M. Ian Gilmour. "Phenotypic comparison of allergic airway responses to house dust mite in three rat strains." American Journal of Physiology-Lung Cellular and Molecular Physiology 284, no. 4 (April 1, 2003): L588—L598. http://dx.doi.org/10.1152/ajplung.00287.2002.

Full text

Abstract:

Brown Norway (BN) rats develop a robust response to antigens in the lung, characterized by a large increase in allergen-specific immune function and pulmonary eosinophilia. The objective of this study was to investigate alternative models by determining whether other rat strains could be sensitized to house dust mite (HDM) antigen and whether the allergic disease process could be worsened with repeated allergen exposure. In general, BN rats sensitized by either subcutaneous or intratracheal routes exhibited increased pulmonary allergy compared with Sprague-Dawley (SD) and Lewis (L) rats. Multiple intratracheal allergen exposures incrementally increased HDM-specific immune function in BN rats but progressively decreased eosinophil recruitment and markers of lung injury. SD rats had more moderate responses, whereas L rats were relatively unresponsive. Because BN rats developed stronger clinical hallmarks of allergic asthma under various immunization regimes compared with SD and L rats, we conclude that the BN is the most appropriate strain for studying allergic asthma-like responses in rats. Phenotypic differences in response to HDM were associated with differences in the Th1/Th2 cytokine balance and antioxidant capacity.

APA, Harvard, Vancouver, ISO, and other styles

34

Martínez, Dalgys, Marlon Munera, Jose Fernando Cantillo, Judith Wortmann, Josefina Zakzuk, Walter Keller, Luis Caraballo, and Leonardo Puerta. "An Engineered Hybrid Protein from Dermatophagoides pteronyssinus Allergens Shows Hypoallergenicity." International Journal of Molecular Sciences 20, no. 12 (June 21, 2019): 3025. http://dx.doi.org/10.3390/ijms20123025.

Full text

Abstract:

The house dust mite (HDM) Dermatophagoides pteronyssinus is an important risk factor for asthma and rhinitis. Allergen specific immunotherapy that is based on recombinant proteins has been proposed for the safer and more efficient treatment of allergic diseases. The aim of this study was to design and obtain a hybrid protein (DPx4) containing antigenic regions of allergens Der p 1, Der p 2, Der p 7, and Der p 10 from this mite. DPx4 was produced in Escherichia coli and its folding was determined by circular dichroism. Non-denaturing dot-blot, ELISA, basophil activation test, dot blot with monoclonal antibodies, ELISA inhibition, and cysteine protease activity assays were performed. Mice that were immunized with DPx4 were also analyzed. We found that DPx4 had no cysteine protease activity and it showed significantly lower IgE reactivity than Der p 1, Der p 2, and D. pteronyssinus extract. DPx4 induced lower basophil activation than Der p 2 and the allergen extract. Immunized mice produced IgG antibodies that inhibited the binding of allergic patient’s IgE to the allergen extract and induced comparatively higher levels of IL-10 than the extract in peripheral blood mononuclear cells (PBMC) culture. These results suggest that DPx4 has immunological properties that are useful for the development of a mite allergy vaccine.

APA, Harvard, Vancouver, ISO, and other styles

35

Chaldanbaeva, A., and V. Bogdanova. "Immunological Characteristics of Pollen and Tick-borne Sensitization in Bishkek Population." Bulletin of Science and Practice 6, no. 6 (June 15, 2020): 84–91. http://dx.doi.org/10.33619/2414-2948/55/12.

Full text

Abstract:

The article presents the results of a study of the prevalence of pollen allergy and allergies to house dust mites among Bishkek population in 2019. The examined patients, aged 4 to 60 years, were divided into groups according to the age periodization of a person. Identification of general and specific IgE antibodies was carried out using modern methods of laboratory diagnosis of the immunological profile. Linked Immunosorbent Assay options such as Chemiluminescence Immunoassay (CLIA) and Immunoblotting were used. The obtained results indicate a widespread sensitization of Bishkek population to pollen allergens, sensitization to house dust mite allergens is more pronounced in the form of a polyvalent allergy. There is also a tendency to increase the prevalence of allergic diseases among the country’s child population. Pollinosis occupy a leading place among allergic diseases in the country due to the fact that weeds prevail in the city’s natural vegetation, which are highly allergenic. Data on the incidence of allergic diseases in Kyrgyzstan, as well as abroad, do not reflect the true spread of allergies, because like most patients with mild forms of allergic diseases do not go to the doctor. Therefore, the early detection, prevention and treatment of allergic diseases is one of the most important issues of modern medicine and biology. It is necessary to create annual flowering calendars of allergenic plants. Round the clock biomonitoring of the air to monitor pollen and air disputes is necessary to inform patients with hay fever. Preventive measures for patients with sensitization to house dust mite allergens include the prevention of mass reproduction of mites, namely the reduction of dust and humidity in rooms.

APA, Harvard, Vancouver, ISO, and other styles

36

Haynes, A. K., M. Sever, P. W. Crockett, R. Jaramillo, A. Zombeck, R. Crohn, and D. Zeldin. "Dust Mite Allergen Reduction Study." Journal of Allergy and Clinical Immunology 125, no. 2 (February 2010): AB30. http://dx.doi.org/10.1016/j.jaci.2009.12.151.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Roux, Michel, Hélène Nguyen, Agnès Viatte, and Robert K. Zeldin. "House Dust Mite-Associated Allergic Rhinitis: Efficacy of STG320 Sublingual Tablets of House Dust Mite Allergen Extracts." Journal of Allergy and Clinical Immunology 137, no. 2 (February 2016): AB61. http://dx.doi.org/10.1016/j.jaci.2015.12.205.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Mosbech, H., A. Dirksen, F. Madsen, P. Stahl Skov, and B. Weeke. "House dust mite asthma." Allergy 42, no. 6 (August 1987): 456–63. http://dx.doi.org/10.1111/j.1398-9995.1987.tb00363.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

SALERNO, MARIA, KAREN HUSS, and RICHARD W. HUSS. "Allergen Avoidance in the Treatment of Dust-mite Allergy and Asthma." Nurse Practitioner 17, no. 10 (October 1992): 53–65. http://dx.doi.org/10.1097/00006205-199210000-00014.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Cheng, Kuang Chuan, Kyung Mi Lee, Marc S. Krug, Tetsuo Watanabe, Mikio Suzuki, In Seong Choe, and Tai-June Yoo. "House dust mite–induced sensitivity in mice." Journal of Allergy and Clinical Immunology 101, no. 1 (January 1998): 51–59. http://dx.doi.org/10.1016/s0091-6749(98)70193-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Sigurdardottir, S. T., B. Adalsteinsdottir, T. Gislason, B. Kristensen, and D. Gislason. "What is House Dust Mite Allergy in a Community with no House Dust Mites?" Journal of Allergy and Clinical Immunology 117, no. 2 (February 2006): S115. http://dx.doi.org/10.1016/j.jaci.2005.12.462.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Thomas, Wayne R., Belinda J. Hales, and Wendy-Anne Smith. "House dust mite allergens in asthma and allergy." Trends in Molecular Medicine 16, no. 7 (July 2010): 321–28. http://dx.doi.org/10.1016/j.molmed.2010.04.008.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Meglio, Paolo. "House dust mite and snail allergy in children." Allergy 58, no. 8 (August 2003): 822–23. http://dx.doi.org/10.1034/j.1398-9995.2003.00284.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Yasueda, Hiroshi, Haruhisa Mita, Yasuo Yui, and Takao Shida. "Measurement of Allergens Associated with Dust Mite Allergy." International Archives of Allergy and Immunology 90, no. 2 (1989): 182–89. http://dx.doi.org/10.1159/000235021.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Sakaguchi, Masahiro, Sakae Inouye, Hiroshi Yasueda, Tatehisa Irie, Susumu Yoshizawa, and Takao Shida. "Measurement of Allergens Associated with Dust Mite Allergy." International Archives of Allergy and Immunology 90, no. 2 (1989): 190–93. http://dx.doi.org/10.1159/000235022.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Hewitt, C. R., A. P. Brown, B. J. Hart, and D. I. Pritchard. "A major house dust mite allergen disrupts the immunoglobulin E network by selectively cleaving CD23: innate protection by antiproteases." Journal of Experimental Medicine 182, no. 5 (November 1, 1995): 1537–44. http://dx.doi.org/10.1084/jem.182.5.1537.

Full text

Abstract:

Asthma is a chronic life-threatening disease of worldwide importance. Although allergic asthma and related atopic conditions correlate strongly with immune sensitization to house dust mites, it is unclear why antigens from mites provoke such powerful allergic immune responses. We have characterized the protease activity of Der p I, the group I protease allergen of the house dust mite Dermatophagoides pteronyssinus, and here report that it cleaves the low-affinity immunoglobulin (Ig) E Fc receptor (CD23) from the surface of human B lymphocytes. Der p I selectively cleaves CD23 and has no effect on the expression of any other B cell surface molecules tested. We speculate that this loss of cell surface CD23 from IgE-secreting B cells may promote and enhance IgE immune responses by ablating an important feedback inhibitory mechanism that normally limits IgE synthesis. Furthermore, since soluble CD23 is reported to promote IgE production, fragments of CD23 released by Der p I may directly enhance the synthesis of IgE. alpha 1-Antiprotease, a pulmonary antiprotease, is also shown to inhibit the cleavage of CD23 by Der p I. This may be significant in the etiopathogenesis of asthma, because other indoor pollutants associated with asthma are known to potently inhibit this antiprotease. These data suggest that the proteolytic activity of Der p I, the group I allergen of the house dust mite D. pteronyssinus, is mechanistically linked to the potent allergenicity of house dust mites. Furthermore, inhibition of Der p I by alpha 1-antiprotease suggests a mechanism by which confounding factors, such as tobacco smoke, may act as a risk factor for allergic asthma.

APA, Harvard, Vancouver, ISO, and other styles

47

Zhang, Jihui, Jie Chen, Jie Zuo, Gary Newton, Mark Stewart, Trevor Perrior, David Garrod, and Clive Robinson. "Allergen Delivery Inhibitors: Characterisation of Potent and Selective Inhibitors of Der p 1 and Their Attenuation of Airway Responses to House Dust Mite Allergens." International Journal of Molecular Sciences 19, no. 10 (October 15, 2018): 3166. http://dx.doi.org/10.3390/ijms19103166.

Full text

Abstract:

Group 1 allergens of house dust mites (HDM) are globally significant triggers of allergic disease. They are considered as initiator allergens because their protease activity enables the development of allergy to a spectrum of unrelated allergens from various sources. This initiator-perpetuator function identifies Group 1 HDM allergens as attractive drug design targets for the first small-molecule approach directed towards a non-human, root cause trigger of allergic disease. The purpose of this study was to: (i) identify exemplar inhibitors of these allergens using Der p 1 as a design template, and (ii) characterise the pharmacological profiles of these compounds using in vitro and in vivo models relevant to allergy. Potent inhibitors representing four different chemotypes and differentiated by mechanism of action were investigated. These compounds prevented the ab initio development of allergy to the full spectrum of HDM allergens and in established allergy they inhibited the recruitment of inflammatory cells and blunted acute allergic bronchoconstriction following aerosol challenge with the full HDM allergen repertoire. Collectively, the data obtained in these experiments demonstrate that the selective pharmacological targeting of Der p 1 achieves an attractive range of benefits against exposure to all HDM allergens, consistent with the initiator-perpetuator function of this allergen.

APA, Harvard, Vancouver, ISO, and other styles

48

Joseph, Karen E., Christina D. Adams, Lesley Cottrell, Mary B. Hogan, and Nevin W. Wilson. "Providing dust mite-proof covers improves adherence to dust mite control measures in children with mite allergy and asthma." Annals of Allergy, Asthma & Immunology 90, no. 5 (May 2003): 550–53. http://dx.doi.org/10.1016/s1081-1206(10)61849-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Lee, J. S., D. Wilson, N. Camuso, D. Patel, and A. Salapatek. "Exposure To Consistent And Controlled Levels Of Aerosolized Dust Mite Allergen Evokes Ocular Symptoms In Dust Mite Allergic Patients." Journal of Allergy and Clinical Immunology 127, no. 2 (February 2011): AB150. http://dx.doi.org/10.1016/j.jaci.2010.12.597.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Harving, H., L. G. Hansen, J. Korsgaard, P. A. Nielsen, O. F. Olsen, J. Rømer, U. G. Svendsen, and O. Østerballe. "House dust mite allergy and anti-mite measures in the indoor environment." Allergy 46, s11 (January 1991): 33–38. http://dx.doi.org/10.1111/j.1398-9995.1991.tb00647.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'Dust mite allergy'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles