Academic literature on the topic 'Duel conjugation'

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Journal articles on the topic "Duel conjugation"

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PRESSON, NORA, NURIA SAGARRA, BRIAN MACWHINNEY, and JOHN KOWALSKI. "Compositional production in Spanish second language conjugation." Bilingualism: Language and Cognition 16, no. 4 (December 20, 2012): 808–28. http://dx.doi.org/10.1017/s136672891200065x.

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Dual-route models of second language (L2) morphology (Clahsen & Felser, 2006; Ullman, 2004) argue that adult L2 learners rely on full-form retrieval, and therefore cannot use combination to produce inflected forms. We tested this prediction with learning of Spanish verb conjugations. Beginning (Experiment 1) and intermediate (Experiment 2) learners (total N = 816) completed 80–90 minutes of web-based training, conjugating regular and subregular verbs in present and preterite tense. Tests of generalization items showed that training led to substantial improvement, equally for metalinguistic and analogical feedback. Comparison with an untrained group showed that gains were maintained 18 weeks after training. In contrast with dual-route model predictions, pre-test accuracy and learning gains were strongly predicted by conjugation pattern, showing that full-form retrieval was insufficient to explain learner performance. Results indicate that adult L2 learners apply compositional analysis, and that conjugation patterns are learned on the basis of their relative cue validity.
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Gupta, Ankita, Shaifali Dubey, and Mayuri Mishra. "Unique Structures, Properties and Applications of Dendrimers." Journal of Drug Delivery and Therapeutics 8, no. 6-s (December 15, 2018): 328–39. http://dx.doi.org/10.22270/jddt.v8i6-s.2083.

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Dendrimers are novel three dimensional, hyperbranched globular nano polymeric architectures. Attractive features like nanoscopic size, narrow polydispersity index and excellent control over molecular structure afford dendrimers with ideal drug delivery ability through encapsulating drugs in their interior or covalently conjugating drugs on their surfaces. The adaptable surface functionalization ability enables covalent conjugation of various targeting molecules onto the surface of dendrimers, thereby allowing for generation of various multifunctional nanodevices for targeted drug delivery applications. Drug delivery researchers are especially enthusiastic about possible utility of dendrimers as drug delivery tool. However, to get the maximum benefits of these novel class macromolecules, a research by collaboration is very much essential. Finally, it is one of the youngest and exciting fields of polymer researches where all branches of science can take part and hence, deserves more intensive attention. Keywords: Dendrimers, Drug Delivery, Targeting, Dual Drug Loading, PAMAM
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Salman, Maen, and Trond Saue. "Charge Conjugation Symmetry in the Finite Basis Approximation of the Dirac Equation." Symmetry 12, no. 7 (July 6, 2020): 1121. http://dx.doi.org/10.3390/sym12071121.

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Four-component relativistic atomic and molecular calculations are typically performed within the no-pair approximation where negative-energy solutions are discarded. These states are, however, needed in QED calculations, wherein, furthermore, charge conjugation symmetry, which connects electronic and positronic solutions, becomes an issue. In this work, we shall discuss the realization of charge conjugation symmetry of the Dirac equation in a central field within the finite basis approximation. Three schemes for basis set construction are considered: restricted, inverse, and dual kinetic balance. We find that charge conjugation symmetry can be realized within the restricted and inverse kinetic balance prescriptions, but only with a special form of basis functions that does not obey the right boundary conditions of the radial wavefunctions. The dual kinetic balance prescription is, on the other hand, compatible with charge conjugation symmetry without restricting the form of the radial basis functions. However, since charge conjugation relates solutions of opposite value of the quantum number κ , this requires the use of basis sets chosen according to total angular momentum j rather than orbital angular momentum ℓ. As a special case, we consider the free-particle Dirac equation, where opposite energy solutions are related by charge conjugation symmetry. We show that there is additional symmetry in that solutions of the same value of κ come in pairs of opposite energy.
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Jang, Hongje, Young-Kwan Kim, and Dal-Hee Min. "Synthesis of partially dextran-coated gold nanoworms and anisotropic structure based dual-strategic cargo conjugation for efficient combinational cancer therapy." Chemical Communications 53, no. 8 (2017): 1385–88. http://dx.doi.org/10.1039/c6cc08821j.

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Pattabiraman, Vijaya R., Matilde Arévalo Ruiz, Régis Boehringer, Benoit Hornsperger, Roy Meoded, Robert C. Tam, and Bertolt Kreft. "Abstract 2138: Creating next-generation biologics using a novel chemistry platform technology." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2138. http://dx.doi.org/10.1158/1538-7445.am2022-2138.

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Abstract Bright Peak Therapeutics is developing a portfolio of differentiated biotherapeutics using chemistry for applications in immuno-oncology and autoimmune diseases. Our unique chemical protein synthesis and engineering platform allows us to fine-tune cytokines and other proteins to interrogate and modulate biological functions by incorporating new functional modifications. Standard recombinant bacterial or cellular expression systems used to produce proteins are largely restricted to using canonical amino acids, which limits access to diverse modifications that can bestow additional functional properties. With chemical protein synthesis technology, canonical and non-canonical modifications including conjugation handles can be easily introduced, ultimately enabling a medicinal chemistry approach for engineering cytokine structures. Enhanced cytokines with differentiated biology developed using this approach can be further elaborated by conjugating to a diverse array of molecules. We first applied our technology platform to identify BPT-143, a rationally designed enhanced IL-2 variant currently in IND-enabling studies. BPT-143 is engineered to have enhanced binding to IL2Rβ and no binding to IL2Rα for improved efficacy and safety independent of the conjugation to a half-life extending 30 kDa PEG. The chemical synthesis technology is robust, reproducible, and scalable. We are applying our platform to enhance a number of other cytokines for use in immuno-oncology and autoimmune diseases. Additionally, our synthetically engineered cytokines can be easily conjugated to monoclonal antibodies as ‘payloads’ using a distinct chemical conjugation technology. A rapid and simple chemical process allows site-selective conjugation of our engineered cytokines to existing antibodies ‘as-is’ to generate novel immunocytokines (IC). This ‘off-the-shelf’ approach is orthogonal to recombinant fusion methods to create ICs and does not require complex recombinant protein expression optimization and lengthy cell-line development. Moreover, it allows rapid screening of cytokine payloads in a structure-activity relationship (SAR) format to identify dual-targeting ICs with precisely tailored properties to generate the desired biological effect. We have prepared a number of ICs including anti-PD-1/IL-2 ICs with various drug-antibody ratio (DAR) and conjugation sites within the antibody. We will provide an overview of the platform technology and present highlights of its application for discovery and development of designer therapeutic cytokines and ICs. Citation Format: Vijaya R. Pattabiraman, Matilde Arévalo Ruiz, Régis Boehringer, Benoit Hornsperger, Roy Meoded, Robert C. Tam, Bertolt Kreft. Creating next-generation biologics using a novel chemistry platform technology [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2138.
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Du, Fangfang, Xuewei Zhao, Wenjing Lu, Zhonghui Guo, Shaomin Shuang, and Chuan Dong. "Dual-ligand functionalized carbon nanodots as green fluorescent nanosensors for cellular dual receptor-mediated targeted imaging." Analyst 144, no. 22 (2019): 6729–35. http://dx.doi.org/10.1039/c9an01530b.

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Wang, Tao, Xiaoge Su, Xuepeng Zhang, Wenhuan Huang, Linkun Huang, Xingyuan Zhang, Xiang Sun, Yi Luo, and Guoqing Zhang. "A combinatory approach towards the design of organic polymer luminescent materials." Journal of Materials Chemistry C 7, no. 32 (2019): 9917–25. http://dx.doi.org/10.1039/c9tc02266j.

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Lee, Jiyeon, Gyoyeon Hwang, Yeon Sun Hong, and Taebo Sim. "One step synthesis of quantum dot–magnetic nanoparticle heterodimers for dual modal imaging applications." Analyst 140, no. 8 (2015): 2864–68. http://dx.doi.org/10.1039/c4an02322f.

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Raja Lakshmi, P., R. Manivannan, P. Jayasudha, and Kuppanagounder P. Elango. "An ICT-based chemodosimeter for selective dual channel sensing of cyanide in an aqueous solution." Analytical Methods 10, no. 20 (2018): 2368–75. http://dx.doi.org/10.1039/c8ay00818c.

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Crossley, M. D., and Sarah Whitehouse. "On conjugation invariants in the dual Steenrod algebra." Proceedings of the American Mathematical Society 128, no. 9 (February 29, 2000): 2809–18. http://dx.doi.org/10.1090/s0002-9939-00-05283-7.

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Dissertations / Theses on the topic "Duel conjugation"

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Rogério, Rodolfo José Bueno [UNESP]. "Aspectos clássicos e quânticos de espinores de dinânima não-usual: espinores de dimenssão de massa um." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/158276.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Na presente tese apresentaremos de forma detalhada o estudo sistemático de uma teoria quântica com férmions de dimensão de massa um que obedecem as estatísticas de Fermi-Dirac, abordando essencialmente sua construção, quantização do campo, análise dos observáveis físicos e aplicações quânticas. Forneceremos todos os detalhes de uma descoberta teórica inesperada da partícula de spin $1/2$ que compõe um conjunto completo de autoespinores com helicidade dual do operador conjugação de carga. Esses espinores recebem o nome de Elko, um acrônimo proveniente do Alemão \textit{Eigenspinoren des Ladungskonjugationsoperators}. Veremos que o elo entre os espaços de representação $(1/2, 0)$ e $(0, 1/2)$ não é dado pela simetria de paridade mas sim pela ``Mágica das matrizes de Pauli'', e, portanto, como consequência a dinâmica de tais campos será regida única e exclusivamente pela dinâmica de Klein-Gordon. Tal fato faz com que o propagador associado ao Elko guarde muita similaridade com o propagador do campo escalar. Intrinsicamente, em sua formulação embrionária, as somas de spin para o Elko mostram um termo que quebra explicitamente a covariância relativística, levando então à apreciação da \textit{Very Special Relativity}, que nada mais é do que um subgrupo do grupo de Lorentz, cuja álgebra deixa as somas de spin invariantes ou covariantes. Entretanto, mostraremos que existe uma liberdade na definição da estrutura dual, a qual permite que seja construída uma teoria local e invariante por transformações de Lorentz, levando, assim, a uma nova física bastante interessante e promissora.
The present thesis covers in details a systematic study of a quantum theory based on mass dimension one fermions which satisfy the Fermi-Dirac statistics, essentially addressing its construction, field quantization, analysis of physical observables and quantum applications. We provide all the details of an unexpected theoretical discovery of a spin 1/2 particle which composes a complete set of dual helicity spinors of the charge conjugation operator. Such spinors are called Elko, an acronym for the German word Eigenspinoren des Ladungskonjugationsoperators. We show that the relation between the representation spaces (1/2,0) and (0,1/2) is given by the “Magic of Pauli matrices” rather than parity symmetry, therefore, as a consequence the dynamic of such fields is governed solely and exclusively by the Klein-Gordon dynamic. Such fact makes the Elko propagator to be very similar to the scalar field propagator Intrinsically, in its embryonic formulation, Elko spin sums shows up a term that explicitly breaks relativistic covariance, leading to the appreciation of Very Special Relativity, a theory which is based on a subgroup of the Lorentz group, whose algebra leaves the spin sums invariant or covariant. However, we show a freedom in the dual structure definition, which allows the construction of a local and Lorentz invariant theory, thus, leading to a very interesting and promising new physics
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Yun, Seonho. "Intracellular Microenvironment Triggered Co-delivery of Anticancer Drugs and Genes." Thesis, 2019. http://hdl.handle.net/2440/120605.

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Currently, infallible cancer treatment has not been achieved. Doxorubicin (DOX), an active anticancer drug, initiates the apoptotic signaling pathway by intercalating topoisomerase-II, resulting in DNA replication disorder and producing reactive oxygen species that can damage DNA and activate cell death receptors. However, long-term DOX administration is always accompanied with serious multidrug resistance (MDR) and adverse side-effects. Therefore, delivery systems for DOX and gene drug, such as miRNA-21 inhibitor (miR-21i) which mitigates MDR, have been developed to reduce side-effects caused by non-selective cellular uptake of co-drugs in the absence of suitable delivery systems. However, difficulties in designing delivery systems for different types of drugs to achieve both high therapeutic efficacy and low side-effects have been reported. In this thesis, various biodegradable and biocompatible smart microgels are developed for DOX and gene co-delivery to achieve maximal anticancer performance and minimal side-effects. The microgel delivery carriers are prepared by crosslinking biocompatible low molecular weight polyethyleneimine (PEI800) using glutathione-cleavable diselenide crosslinkers. To the carriers, DOX is conjugated via various intracellular microenvironment sensitive linkers, and genes are electrostatically loaded to glutathione-cleavable polyethyleneimine. Finally, anionic hyaluronic acid (HA) surface coating is able to inhibit serum protein adsorption during blood circulation and promote HA receptor-mediated endocytosis for selective metastatic cancer cells. The hydrodynamic sizes of resulting nano-drugs at 100–200 nm allow prolonged circulation. The developed nano-drugs degrade into less than 10 nm fragments in the glutathione-rich cytosol of cancer cells by cleaving diselenide crosslinkers, allowing intensive gene release and complete urinary excretion. Real-time tracks of release profiles are developed using fluorescence quenching technique. On the other hand, to eliminate premature release, DOX is conjugated to microgel carriers through various linkers for efficiently controlled spatiotemporal release in cancer lysosomes, such as acid-responsive hydrazone linkers, glutathione-cleavable diselenide linkers and enzyme-cleavable peptide linkers. The system comprising of DOX with a hydrazone bond demonstrates 4.4-fold higher in vitro anticancer performance on MDA-MB-231 cell line than free DOX. The nano-drug system of miR-21i and conjugated DOX via hydrazone and diselenide dual bonds completely surpasses DOX premature leakage in physiological condition and results in a high survival rate of over 95 % for HEK293T kidney cell line at a DOX concentration of 2.5 μg mL−1, but it reveals 3.2-fold increase in therapeutic effect on the multidrug-resistant cancer cell line of MDA-MB-231-R12w compared with free DOX. To simplify DOX loading process, diselenide crosslinkers can be used for both microgel synthesis and DOX conjugation to produce a simultaneous release system of gene and DOX in cytosol. The introduction of ATP aptamer to the miR-21i and DOX co-delivery system further increases intracellular DOX accumulation in MDA-MD-231-R12w cells with 4.2-fold higher anticancer performance than free DOX but with low cytotoxicity to healthy cells. To achieve sequential release, the nano-drug system of miR-21i and conjugated DOX with a caspase-3-cleavable DEVDC peptide linker enables the step release of miR-21i followed by DOX. Compared with free DOX, this systems demonstrates a 7.3-fold increase in anticancer effect on MDA-MB-231-R24w and negligible side effects. In summary, we have developed various smart nano-drugs with outstanding advantages of low cytotoxicity, complete biodegradability, targeting and selective delivery and high anticancer performance to MDR cells. Our approach suppresses traditional gene and drug delivery concepts, and advances knowledge for successive design of delivery systems in clinical applications.
Thesis (Ph.D.) -- University of Adelaide, School of Chemical Engineering and Advanced Materials, 2019
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Books on the topic "Duel conjugation"

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Solymar, L., D. Walsh, and R. R. A. Syms. Optoelectronics. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198829942.003.0013.

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The properties of light detectors and light emitting diodes (LEDs) are discussed. Electro-optic, photorefractive, and nonlinear materials are introduced. The phenomenon of phase conjugation is explained. Interaction between acoustic and light waves is shown to be possible. The significance of integrated optics is discussed. Bistability due to the action of nonlinear Fabry–Perot cavities is explained. Optical switching is shown to be an application of micro-electro-mechanical effects. The complicated phenomenon electro-absorption in quantum well structures and its applications are discussed.
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Zirnbauer, Martin R. Symmetry classes. Edited by Gernot Akemann, Jinho Baik, and Philippe Di Francesco. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780198744191.013.3.

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This article examines the notion of ‘symmetry class’, which expresses the relevance of symmetries as an organizational principle. In his 1962 paper The threefold way: algebraic structure of symmetry groups and ensembles in quantum mechanics, Dyson introduced the prime classification of random matrix ensembles based on a quantum mechanical setting with symmetries. He described three types of independent irreducible ensembles: complex Hermitian, real symmetric, and quaternion self-dual. This article first reviews Dyson’s threefold way from a modern perspective before considering a minimal extension of his setting to incorporate the physics of chiral Dirac fermions and disordered superconductors. In this minimally extended setting, Hilbert space is replaced by Fock space equipped with the anti-unitary operation of particle-hole conjugation, and symmetry classes are in one-to-one correspondence with the large families of Riemannian symmetric spaces.
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Book chapters on the topic "Duel conjugation"

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Puthenveetil, Sujiet. "Utilizing Solid-Phase to Enable High-Throughput, Site-Specific Conjugation and Dual-Labeled Antibody and Fab Conjugates." In Methods in Molecular Biology, 99–112. New York, NY: Springer US, 2019. http://dx.doi.org/10.1007/978-1-4939-9929-3_7.

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Palacio-Castañeda, Valentina, Roland Brock, and Wouter P. R. Verdurmen. "Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen." In Methods in Molecular Biology, 129–41. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2010-6_8.

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AbstractPhosphorodiamidate morpholino oligomers (PMOs) offer great promise as therapeutic agents for translation blocking or splice modulation due to their high stability and affinity for target sequences. However, in spite of their neutral charge as compared to natural oligonucleotides or phosphorothioate analogs, they still show little permeability for cellular membranes, highlighting the need for effective cytosolic delivery strategies. In addition, the implementation of strategies for efficient cellular targeting is highly desirable to minimize side effects and maximize the drug dose at its site of action. Anthrax toxin is a three-protein toxin of which the pore-forming protein anthrax protective antigen (PA) can be redirected to a receptor of choice and lethal factor (LF), one of the two substrate proteins, can be coupled to various cargoes for efficient cytosolic cargo delivery. In this protocol, we describe the steps to produce the proteins and protein conjugates required for cytosolic delivery of PMOs through the cation-selective pore generated by anthrax protective antigen. The method relies on the introduction of a unique cysteine at the C-terminal end of a truncated LF (aa 1–254), high-yield expression of the (truncated) toxin proteins in E. coli, functionalization of a PMO with a maleimide group and coupling of the maleimide-functionalized PMO to the unique cysteine on LF by maleimide-thiol conjugation chemistry. Through co-administration of PA with LF-PMO conjugates, an efficient cytosolic delivery of PMOs can be obtained.
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Golz, Julia Carolin, and Kerstin Stingl. "Natural Competence and Horizontal Gene Transfer in Campylobacter." In Current Topics in Microbiology and Immunology, 265–92. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65481-8_10.

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AbstractThermophilic Campylobacter, in particular Campylobacter jejuni, C. coli and C. lari are the main relevant Campylobacter species for human infections. Due to their high capacity of genetic exchange by horizontal gene transfer (HGT), rapid adaptation to changing environmental and host conditions contribute to successful spreading and persistence of these foodborne pathogens. However, extensive HGT can exert dangerous side effects for the bacterium, such as the incorporation of gene fragments leading to disturbed gene functions. Here we discuss mechanisms of HGT, notably natural transformation, conjugation and bacteriophage transduction and limiting regulatory strategies of gene transfer. In particular, we summarize the current knowledge on how the DNA macromolecule is exchanged between single cells. Mechanisms to stimulate and to limit HGT obviously coevolved and maintained an optimal balance. Chromosomal rearrangements and incorporation of harmful mutations are risk factors for survival and can result in drastic loss of fitness. In Campylobacter, the restricted recognition and preferential uptake of free DNA from relatives are mediated by a short methylated DNA pattern and not by a classical DNA uptake sequence as found in other bacteria. A class two CRISPR-Cas system is present but also other DNases and restriction–modification systems appear to be important for Campylobacter genome integrity. Several lytic and integrated bacteriophages have been identified, which contribute to genome diversity. Furthermore, we focus on the impact of gene transfer on the spread of antibiotic resistance genes (resistome) and persistence factors. We discuss remaining open questions in the HGT field, supposed to be answered in the future by current technologies like whole-genome sequencing and single-cell approaches.
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Khattak, Rozina. "Catalytic Behavior of Extended π-Conjugation in the Kinetics of Sensitizer-Mediator Interaction." In Recent Advances in Chemical Kinetics [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106511.

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This chapter discusses the catalytic effect of extended π-conjugation on the electron transfer process between ferricyphen-ferrocyanide and ferricypyr-ferrocyanide in an aqueous medium. Ferricyphen and ferricypyr may be feasible options for the sensitizer in dye-sensitized solar cells due to their high reduction potential, stability, capability as an outer-sphere oxidant, and photosensitivity. Meanwhile, ferrocyanide could be used as a mediator in DSSCs instead of iodide to avoid iodate production and achieve a similar reduction potential and stability. This chapter compared the ability of competent putative sensitizers to oxidize the likely mediator in water. In contrast to the 2,2′-dipyridyl chelate, the extended π-conjugation in 1,10-phenanthroline accelerated the redox process by increasing the electron affinity of ferricyphen as compared to ferricypyr. The reactions had the same kinetics but different rate constants, indicating that the ferricyphen-ferrocyanide reaction was several times faster than the ferricypyr-ferrocyanide reaction, revealing and confirming the catalytic influence of extended π-conjugation on the redox process.
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Janda, Gwen Eva, Johanna Laakso, and Helle Metslang. "Person marking." In The Oxford Guide to the Uralic Languages, 894–903. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780198767664.003.0045.

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This chapter investigates patterns of verbal and nominal person marking in Uralic languages. Person is combined with number: there are three persons in singular and plural, in some languages also in dual. Person marking on finite verbs (in many Uralic languages, in case of negation it is placed on the negative auxiliary verb) is used in subject agreement, and in Mordvin, Ugric, and Samoyedic there exists an additional paradigm for object agreement (aka objective conjugation). Adnominal person markers, traditionally known as possessive suffixes, can encode possessor person but also a variety of features connected with referentiality or definiteness. With non-finite verbs they mark subject agreement in dependent clauses. The functions, uses and productivity of possessive suffixes vary greatly within Uralic.
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Wagner-Nagy, Beáta, and Sándor Szeverényi. "Samoyedic." In The Oxford Guide to the Uralic Languages, 658–73. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780198767664.003.0034.

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The Samoyedic branch now consists of the following languages indigenous to Western Siberia: Nenets, Enets, Nganasan, and Selkup. Two Southern Samoyedic languages, Mator and Kamas, are extinct, and also the remaining Samoyedic languages are severely or critically endangered. This chapter describes the characteristics of Samoyedic languages and their background in the reconstructible Proto-Samoyedic. All Samoyedic languages are predominantly agglutinative, but Northern Samoyedic (Enets, Nenets, Nganasan) shows a high degree of fusion in the marking of case and number. In addition to singular and plural, Samoyedic languages have a dual number. Similarly to Ugric and Mordvin, their verbal inflection includes a distinct objective conjugation (object-agreement paradigm). As concerns their syntax, the Samoyedic languages are characterized by PRO-DROP and diverse types of non-finite subordination.
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Reutenauer, Christophe. "Conjugates and Factors." In From Christoffel Words to Markoff Numbers, 109–24. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198827542.003.0016.

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Christoffel words are naturally cyclic objects. They may be defined by the Cayley graphs of finite cyclic groups. They have many characterizations through their conjugation classes; among them, one is obtained using the Burrows–Wheeler transform (Mantaci, Restivo, and Sciortino); another one is due to Pirillo. The sets of their circular factors have many remarkable properties; in particular the number of them of length k is k+1, if k is smaller than the length of the Christoffel word, and it is a characteristic property (Borel and the author), reminiscent of the similar property of Sturmian sequences. A related characterization, similar to that of Droubay and Pirillo for Sturmian sequences, rests on the count of palindromic factors. The set of finite Sturmian words, that is, the set of all factors of all Christoffel words, coincides with the set of balanced words (Dulucq and Gouyou–Beauchamps).
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Abu-El-Rub, Ejlal, Hana M. Zegallai, Basma Milad Aloud, Saravanan Sekaran, and Donald W. Miller. "Magnetic Nanoparticles for Imaging, Diagnosis, and Drug-Delivery Applications." In Bionanotechnology: Next-Generation Therapeutic Tools, 98–129. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815051278122010007.

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Magnetic Nanoparticles (MNPs) have gained interest within the research community due to their therapeutic potential in a variety of medical applications. MNPs are generally composed of a metallic core stabilized by the addition of an outer shell that can be further functionalized through the absorbance or conjugation of various targeting ligands. The magnetic properties of these nanoparticles can be utilized for imaging, localized drug delivery, and enhanced diagnostic detection. This chapter highlights the applications of MNPs to enhance magnetic resonance imaging (MRI) capabilities and improve the delivery of therapeutic agents to difficult-to-reach areas in the body. In addition, recent advances in the use of MNPs in stem cell therapy for both the tracking and monitoring of stem cell distribution in the body and improving engraftment and differentiation in stem cell therapy are discussed. Finally, examples of the incorporation of MNPs in diagnostic assays to improve rapid and realtime detection capabilities of many diseases, including cancer, cardiovascular diseases, and pathogen infections, are provided.
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Sipos, Mária. "North Khanty." In The Oxford Guide to the Uralic Languages, 581–607. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780198767664.003.0031.

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This chapter aims to describe the northern dialect of Khanty, which is an example of geographical dialect continuum, i.e. the variants along the Ob River have no definable boundaries between neighbouring variants, but the northernmost and southernmost subdialects differ to a considerable extent. The description focuses basically on the Kazym Khanty variant, which is a dialect of remarkable countenance, and also used in the Khanty-language newspaper, consequently, it has developed relatively advanced literary norms. Although this chapter describes a certain variant from synchronic aspect, compromise must be made on two issues. Firstly, owing to the dialectal situation just described, the description includes some additions concerning the differences in phonological systems, morphophonological rules, case systems, the use of dual in verb conjugations, etc. of further lects, if necessary. Secondly, as present-day Khanty is spoken mostly by bilingual people, numerous phenomena emblematic of contact-induced language change must be mentioned.
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Gedda, Gangaraju, Arun Bhupathi, and V. L. N. Balaji Gupta Tiruveedhi. "Naturally Derived Carbon Dots as Bioimaging Agents." In BioMechanics and Functional Tissue Engineering [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96912.

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The recent advances in nanoscience and technology have opened new avenues for carbon-based nanomaterials. Especially, Carbon dots (CDs) have gained significant attention due to their simple, economic and rapid green synthesis. These materials exhibit excellent water solubility, fluorescence emission, high fluorescence quantum yield, Ultraviolet (UV) to Infrared (IR) range absorbance and high bio-compatibility. Therefore, these materials are widely used for various biological applications including bio-imaging. With the integration and doping of surface passive agents and elements, respectively influenced the enhancement of fluorescence property of CDs. Also, the conjugation of receptor-based targeting ligands leads to targeted bioimaging. CDs in combination with other imaging contrast agents lead to the development of novel contrast agents for bimodal imaging and multimodal imaging techniques. The combination of diagnostic CDs with therapeutic agents resulted in the formation of theragnostic CDs for image guided therapies. In this chapter, a comprehensive view on the top-down and bottom–up green synthesis methods for naturally derived CDs discussed. Further, unique physical, chemical, optical and biological properties of CDs described. Finally, fluorescence based bimodal and multimodal imaging techniques also described.
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Conference papers on the topic "Duel conjugation"

1

Yu, Bowen, and Kwun-lon Ting. "Free-Form Conjugation Theory." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48337.

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The paper presents the first theory and practice for free-form conjugation design and extends the conventional conjugate tooth profiles to free-form tooth profiles. It presents a conjugation theory that offers a rigorous correspondence between a conjugate pair and the cutter profile or contact path, discovers the necessary and sufficient conditions for non-undercutting with differential curves, and thus extends the traditional free-form single surface modeling to dual conjugate surface modeling. Free-form conjugation modeling and synthesis can be carried out through the cutter profile or the contact path surface. The paper offers a general theory and methodology for free-form modeling and synthesis of planar conjugation, extend the traditional single surface free-form modeling to dual-surface conjugation modeling, and establishes the foundation that will offer much needed design freedom enabling one searching for conjugate surfaces with optimal or desired performance in any transmission involving contact surfaces. The theory is demonstrated in gear tooth profile design through splines and thus provides a fresh perspective on gearing.
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Choudhary, Usha, Vijay Janyani, and Muhammad Arif Khan. "Dual Frame OFDM with Optical Phase Conjugation." In 2020 29th Wireless and Optical Communications Conference (WOCC). IEEE, 2020. http://dx.doi.org/10.1109/wocc48579.2020.9114941.

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3

Kwon, Young K., and Frank S. Barnes. "Laser resonator design with dual phase conjugation mirrors." In High-Power Lasers and Applications, edited by Alexis V. Kudryashov. SPIE, 2002. http://dx.doi.org/10.1117/12.469480.

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Lukin, Vladimir P., and Boris V. Fortes. "Influence of wavefront dislocations on phase conjugation instability at thermal blooming compensation." In SPIE's 1995 Symposium on OE/Aerospace Sensing and Dual Use Photonics, edited by J. Christopher Dainty. SPIE, 1995. http://dx.doi.org/10.1117/12.211943.

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5

Gan, Mikhail A., Alexey Leshchev, Igor S. Potyemin, Michael V. Vasil'ev, and Vladimir Y. Venediktov. "Numerical design and modeling of the telescopic systems compensated via phase conjugation." In SPIE's 1995 Symposium on OE/Aerospace Sensing and Dual Use Photonics, edited by Pierre Y. Bely and James B. Breckinridge. SPIE, 1995. http://dx.doi.org/10.1117/12.210937.

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6

Andreev, Rostislav B., Valery M. Irtuganov, Alexey Leshchev, Pavel M. Semenov, Michael V. Vasil'ev, and Vladimir Y. Venediktov. "Experimental realization of the laser telescope with overall compensation for distortions via phase conjugation." In SPIE's 1995 Symposium on OE/Aerospace Sensing and Dual Use Photonics, edited by Pierre Y. Bely and James B. Breckinridge. SPIE, 1995. http://dx.doi.org/10.1117/12.210938.

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7

Ibsen, Morten, Michael K. Durkin, and Richard I. Laming. "Chirped Moiré Fibre Gratings Operating on two Wavelength-Channels for use as Dual Channel Dispersion Compensators." In Bragg Gratings, Photosensitivity, and Poling in Glass Fibers and Waveguides. Washington, D.C.: Optica Publishing Group, 1997. http://dx.doi.org/10.1364/bgppf.1997.btua.6.

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Dispersion compensation is necessary in order to allow high data rate transmission through the installed standard fibre links. Several dispersion compensation techniques exists, including dispersion compensating fibre, phase conjugation and chirped fibre gratings. Of these, chirped fibre gratings offer many advantages including compactness, low-loss and low nonlinearity. Recent error-free 10 Gbit/s and 40 Gbit/s transmission experiments at 1.55 μm over 109 km of standard fibre together with the possibility of simultaneous compensation of 2nd and 3rd order dispersion confirm the potential of this solution [1,2,3].
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8

Mendillo, Christopher B., Kuravi Hewawasam, Jason Martel, Timothy A. Cook, Supriya Chakrabarti, Frans Snik, and David Doelman. "Dual-polarization electric field conjugation and applications for vector vortex coronagraphs." In Techniques and Instrumentation for Detection of Exoplanets X, edited by Stuart B. Shaklan and Garreth J. Ruane. SPIE, 2021. http://dx.doi.org/10.1117/12.2594775.

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9

Mizes, Howard A., and Esther M. Conwell. "Stabilization of polarons in conjugated polymers due to finite conjugation lengths." In IS&T/SPIE's Symposium on Electronic Imaging: Science and Technology, edited by Esther M. Conwell, Milan Stolka, and M. Robert Miller. SPIE, 1993. http://dx.doi.org/10.1117/12.151142.

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10

Baba, Waqas, and Sajid Maqsood. "Enhancing techno-functional and bioactive properties of whey proteins by conjugation with quercetin using combined treatment of redox pair and ultrasonication." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/jtxr7155.

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Camel whey-quercetin conjugates were fabricated via free radicals using a combination of ultrasonication treatment and a redox-pair (ascorbic acid/H2O2). Conjugation of whey with quercetin was confirmed using UV-Vis. spectroscopy, FTIR and SDS-PAGE. UV-Visible spectroscopy showed a bathochromic shift and appearance of a hump around ≈350 nm (absent in whey sample) that can be attributed to binding of quercetin with whey protein. As indicated by FTIR, the association of whey with quercetin took place via covalent (appearance of new peak at 3399 cm-1) as well as noncovalent linkages (shift-ing of peak at 3271 cm-1, 1655 cm-1 (amide I), 1534 cm-1 and 1422 cm-1 (Amide II). The appearance of new peaks in UV-Visible spectroscopy and FTIR of conjugates was resolved using a second derivative of the spectrum. Reducing SDS-PAGE revealed shifting of protein bands towards higher molecular weight due to increase in the mass of conjugates that can be attributed to covalent conjugation between whey and quercetin. A significant improvement in the functionality and bioac-tive properties was witnessed after conjugation of whey with quercetin. Ultrasonication improved the emulsifying and foaming properties while a combination of ultrasonication and redox pair method enhanced the antioxidant properties. Moreover, conjugated samples showed higher inhibition of enzymatic markers involved in diabetes (α-amylase & DPP-IV) and obesity (cholesterol esterase & lipase) with highest potential recorded for conjugates produced using ultrasonication only. Therefore, ultrasonication can be successfully used individually as well as in combination with redox-pair for produc-tion of whey-quercetin conjugates with enhanced bioactive and techno-functional properties.
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