Journal articles on the topic 'Duchenne, animal models, DMD'
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Lim, Kenji Rowel Q., Quynh Nguyen, Kasia Dzierlega, Yiqing Huang, and Toshifumi Yokota. "CRISPR-Generated Animal Models of Duchenne Muscular Dystrophy." Genes 11, no. 3 (March 24, 2020): 342. http://dx.doi.org/10.3390/genes11030342.
Full textNakamura, Akinori, and Shin'ichi Takeda. "Mammalian Models of Duchenne Muscular Dystrophy: Pathological Characteristics and Therapeutic Applications." Journal of Biomedicine and Biotechnology 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/184393.
Full textDonandt, Tina, Stefan Hintze, Sabine Krause, Eckhard Wolf, Benedikt Schoser, Maggie C. Walter, and Peter Meinke. "Isolation and Characterization of Primary DMD Pig Muscle Cells as an In Vitro Model for Preclinical Research on Duchenne Muscular Dystrophy." Life 12, no. 10 (October 21, 2022): 1668. http://dx.doi.org/10.3390/life12101668.
Full textWilson, Kristin, Crystal Faelan, Janet C. Patterson-Kane, Daniel G. Rudmann, Steven A. Moore, Diane Frank, Jay Charleston, Jon Tinsley, G. David Young, and Anthony J. Milici. "Duchenne and Becker Muscular Dystrophies: A Review of Animal Models, Clinical End Points, and Biomarker Quantification." Toxicologic Pathology 45, no. 7 (October 2017): 961–76. http://dx.doi.org/10.1177/0192623317734823.
Full textSayers, Stephen P. "The Role of Exercise as a Therapy for Children with Duchenne Muscular Dystrophy." Pediatric Exercise Science 12, no. 1 (February 2000): 23–33. http://dx.doi.org/10.1123/pes.12.1.23.
Full textEnglish, Katherine G., Andrea L. Reid, Adrienne Samani, Gerald J. F. Coulis, S. Armando Villalta, Christopher J. Walker, Sharon Tamir, and Matthew S. Alexander. "Next-Generation SINE Compound KPT−8602 Ameliorates Dystrophic Pathology in Zebrafish and Mouse Models of DMD." Biomedicines 10, no. 10 (September 26, 2022): 2400. http://dx.doi.org/10.3390/biomedicines10102400.
Full textWong, Tatianna Wai Ying, Abdalla Ahmed, Grace Yang, Eleonora Maino, Sydney Steiman, Elzbieta Hyatt, Parry Chan, et al. "A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy." Disease Models & Mechanisms 13, no. 9 (September 1, 2020): dmm045369. http://dx.doi.org/10.1242/dmm.045369.
Full textWells, Dominic J. "Tracking progress: an update on animal models for Duchenne muscular dystrophy." Disease Models & Mechanisms 11, no. 6 (June 1, 2018): dmm035774. http://dx.doi.org/10.1242/dmm.035774.
Full textEchigoya, Yusuke, Nhu Trieu, William Duddy, Hong M. Moulton, HaiFang Yin, Terence A. Partridge, Eric P. Hoffman, et al. "A Dystrophin Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping." International Journal of Molecular Sciences 22, no. 23 (December 2, 2021): 13065. http://dx.doi.org/10.3390/ijms222313065.
Full textHughes, K. J., A. Rodriguez, K. M. Flatt, S. Ray, A. Schuler, B. Rodemoyer, V. Veerappan, et al. "Physical exertion exacerbates decline in the musculature of an animal model of Duchenne muscular dystrophy." Proceedings of the National Academy of Sciences 116, no. 9 (February 12, 2019): 3508–17. http://dx.doi.org/10.1073/pnas.1811379116.
Full textZhang, Yu, Hui Li, Yi-Li Min, Efrain Sanchez-Ortiz, Jian Huang, Alex A. Mireault, John M. Shelton, et al. "Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system." Science Advances 6, no. 8 (February 2020): eaay6812. http://dx.doi.org/10.1126/sciadv.aay6812.
Full textRiddell, Dominique O., John C. W. Hildyard, Rachel C. M. Harron, Dominic J. Wells, and Richard J. Piercy. "Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy." Wellcome Open Research 6 (August 17, 2022): 354. http://dx.doi.org/10.12688/wellcomeopenres.17398.2.
Full textRiddell, Dominique O., John C. W. Hildyard, Rachel C. M. Harron, Dominic J. Wells, and Richard J. Piercy. "Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy." Wellcome Open Research 6 (December 20, 2021): 354. http://dx.doi.org/10.12688/wellcomeopenres.17398.1.
Full textKlymiuk, N., C. Thirion, K. Burkhardt, A. Wuensch, S. Krause, A. Richter, B. Kessler, et al. "238 TAILORED PIG MODEL OF DUCHENNE MUSCULAR DYSTROPHY." Reproduction, Fertility and Development 24, no. 1 (2012): 231. http://dx.doi.org/10.1071/rdv24n1ab238.
Full textMcGreevy, J. W., C. H. Hakim, M. A. McIntosh, and D. Duan. "Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy." Disease Models & Mechanisms 8, no. 3 (March 1, 2015): 195–213. http://dx.doi.org/10.1242/dmm.018424.
Full textHerbelet, Sandrine, Arthur Rodenbach, Boel De Paepe, and Jan L. De Bleecker. "Anti-Inflammatory and General Glucocorticoid Physiology in Skeletal Muscles Affected by Duchenne Muscular Dystrophy: Exploration of Steroid-Sparing Agents." International Journal of Molecular Sciences 21, no. 13 (June 28, 2020): 4596. http://dx.doi.org/10.3390/ijms21134596.
Full textRybalka, Emma, Cara Timpani, Danielle Debruin, Ryan Bagaric, Dean Campelj, and Alan Hayes. "The Failed Clinical Story of Myostatin Inhibitors against Duchenne Muscular Dystrophy: Exploring the Biology behind the Battle." Cells 9, no. 12 (December 10, 2020): 2657. http://dx.doi.org/10.3390/cells9122657.
Full textMaruyama, Rika, and Toshifumi Yokota. "Molecular Diagnosis and Novel Therapies for Neuromuscular Diseases." Journal of Personalized Medicine 10, no. 3 (September 16, 2020): 129. http://dx.doi.org/10.3390/jpm10030129.
Full textMorroni, Jacopo, Leonardo Schirone, Daniele Vecchio, Carmine Nicoletti, Luca D’Ambrosio, Valentina Valenti, Sebastiano Sciarretta, Biliana Lozanoska-Ochser, and Marina Bouchè. "Accelerating the Mdx Heart Histo-Pathology through Physical Exercise." Life 11, no. 7 (July 17, 2021): 706. http://dx.doi.org/10.3390/life11070706.
Full textMordechay, Sharon, Shaun Smullen, Paul Evans, Olga Genin, Mark Pines, and Orna Halevy. "Differential Effects of Halofuginone Enantiomers on Muscle Fibrosis and Histopathology in Duchenne Muscular Dystrophy." International Journal of Molecular Sciences 22, no. 13 (June 30, 2021): 7063. http://dx.doi.org/10.3390/ijms22137063.
Full textDubuisson, Nicolas, Romain Versele, Chloé Planchon, Camille M. Selvais, Laurence Noel, Michel Abou-Samra, and María A. Davis-López de Carrizosa. "Histological Methods to Assess Skeletal Muscle Degeneration and Regeneration in Duchenne Muscular Dystrophy." International Journal of Molecular Sciences 23, no. 24 (December 16, 2022): 16080. http://dx.doi.org/10.3390/ijms232416080.
Full textHildyard, John C. W., Dominique O. Riddell, Rachel C. M. Harron, Faye Rawson, Emma M. A. Foster, Claire Massey, Frances Taylor-Brown, Dominic J. Wells, and Richard J. Piercy. "The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy." Wellcome Open Research 7 (September 23, 2022): 238. http://dx.doi.org/10.12688/wellcomeopenres.18251.1.
Full textCampbell, Katherine, Louise Rodino-Klapac, Zarife Sahenk, Chris Shilling, Sarah Lewis, Dawn Bowles, Steven Gray, et al. "Revertant muscle fibers expressing dystrophin do not tolerize the immune system in Duchenne muscular dystrophy: lessons learned from a Phase I clinical trial (96.9)." Journal of Immunology 184, no. 1_Supplement (April 1, 2010): 96.9. http://dx.doi.org/10.4049/jimmunol.184.supp.96.9.
Full textMoorwood, Catherine, Neha Soni, Gopal Patel, Steve D. Wilton, and Tejvir S. Khurana. "A Cell-Based High-Throughput Screening Assay for Posttranscriptional Utrophin Upregulation." Journal of Biomolecular Screening 18, no. 4 (October 30, 2012): 400–406. http://dx.doi.org/10.1177/1087057112465648.
Full textAndre, Alexander B., Liqiang Zhang, Jalen D. Nix, Nora Elmadbouly, Alexandra R. Lucas, Jeanne Wilson-Rawls, and Alan Rawls. "Myxomavirus Serp-1 Protein Ameliorates Inflammation in a Mouse Model of Duchenne Muscular Dystrophy." Biomedicines 10, no. 5 (May 17, 2022): 1154. http://dx.doi.org/10.3390/biomedicines10051154.
Full textBremner, Samantha B., Christian J. Mandrycky, Andrea Leonard, Ruby M. Padgett, Alan R. Levinson, Ethan S. Rehn, J. Manuel Pioner, Nathan J. Sniadecki, and David L. Mack. "Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues." Journal of Tissue Engineering 13 (January 2022): 204173142211196. http://dx.doi.org/10.1177/20417314221119628.
Full textMázala, Davi A. G., Robert W. Grange, and Eva R. Chin. "The role of proteases in excitation-contraction coupling failure in muscular dystrophy." American Journal of Physiology-Cell Physiology 308, no. 1 (January 1, 2015): C33—C40. http://dx.doi.org/10.1152/ajpcell.00267.2013.
Full textFiorillo, Alyson A., Christopher B. Tully, Jesse M. Damsker, Kanneboyina Nagaraju, Eric P. Hoffman, and Christopher R. Heier. "Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone." Physiological Genomics 50, no. 9 (September 1, 2018): 735–45. http://dx.doi.org/10.1152/physiolgenomics.00134.2017.
Full textMartins, Isabela M., Lygia M. M. Malvestio, Jair R. Engracia-Filho, Gustavo S. Claudiano, Flávio R. Moraes, and Julieta R. E. Moraes. "Mast cells in the pathophysiology of Duchenne muscular dystrophy in Golden Retriever dogs." Pesquisa Veterinária Brasileira 40, no. 10 (October 2020): 791–97. http://dx.doi.org/10.1590/1678-5150-pvb-6340.
Full textMartins, D. S., N. Z. Saraiva, J. M. Garcia, C. E. Ambrósio, M. Zatz, and M. A. Miglino. "201 CHARACTERIZATION OF CANINE EMBRYONIC GERM CELLS: AN EXPERIMENTAL MODEL FOR CELL THERAPY." Reproduction, Fertility and Development 18, no. 2 (2006): 209. http://dx.doi.org/10.1071/rdv18n2ab201.
Full textBuscara, Laurine, David-Alexandre Gross, and Nathalie Daniele. "Of rAAV and Men: From Genetic Neuromuscular Disorder Efficacy and Toxicity Preclinical Studies to Clinical Trials and Back." Journal of Personalized Medicine 10, no. 4 (November 28, 2020): 258. http://dx.doi.org/10.3390/jpm10040258.
Full textPeres, M. A., M. Nichi, A. M. Rocha, C. M. Mendes, P. B. Cavalcanti, J. S. A. Gonçalves, J. A. Visintin, and M. E. O. A. Assumpção. "230 COMPARISON OF SEMEN SAMPLES FROM NORMAL AND MUSCULAR DYSTROPHY AFFECTED ANIMAL MODELS BY THIOBARBITURIC ACID REACTIVE SUBSTANCES TEST AND FLUORESCENCE-ACTIVATED CELL SORTING ANALYSIS." Reproduction, Fertility and Development 21, no. 1 (2009): 213. http://dx.doi.org/10.1071/rdv21n1ab230.
Full textAlves, Flávio R., Matheus L. T. Feitosa, André Gatti, Leandro Fadel, Silvana M. Unruh, Carlos E. Ambrósio, Franklin A. Sterman, Ana C. B. C. F. Pinto, and Maria A. Miglino. "Imagem radiográfica da cavidade torácica de cães Golden Retriever acometidos pela distrofia muscular." Pesquisa Veterinária Brasileira 29, no. 2 (February 2009): 99–104. http://dx.doi.org/10.1590/s0100-736x2009000200002.
Full textAbreu, Dilayla K., Carolina Costola-de-Souza, Dayane Alcântara, Elaine A. F. Rodrigues, Karla P. C. Araújo, Paulo C. Maiorka, Maria A. Miglino, and Carlos E. Ambrósio. "Estudo morfofuncional dos rins de cães da raça Golden Retriever afetados pela distrofia muscular (GRMD)." Pesquisa Veterinária Brasileira 32, no. 10 (October 2012): 1067–72. http://dx.doi.org/10.1590/s0100-736x2012001000022.
Full textMbakam, C. Happi, J. Rousseau, G. Tremblay, and J. Tremblay. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S77—S78. http://dx.doi.org/10.1016/j.nmd.2021.07.119.
Full textEgorova, T., A. Polikarpova, I. Savchenko, S. Vassilieva, Y. Ivanova, V. Skopenkova, M. Dzhenkova, et al. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S73. http://dx.doi.org/10.1016/j.nmd.2021.07.104.
Full textDubuisson, N., M. Abou-Samra, M. Davis, L. Noel, C. Selvais, and S. Brichard. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S76. http://dx.doi.org/10.1016/j.nmd.2021.07.113.
Full textHong, A. Vu, N. Bourg-Alibert, P. Sanatine, J. Poupiot, K. Charton, E. Gicquel, M. Spinazzi, I. Richard, and D. Israeli. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S77. http://dx.doi.org/10.1016/j.nmd.2021.07.118.
Full textLambert, M., Y. Zhang, J. Spinazzola, J. Widrick, J. Conner, and L. Kunkel. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S78. http://dx.doi.org/10.1016/j.nmd.2021.07.120.
Full textAbou-Samra, M., A. Marino, C. Selvais, N. Dubuisson, L. Noel, C. Beauloye, S. Horman, and S. Brichard. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S76—S77. http://dx.doi.org/10.1016/j.nmd.2021.07.116.
Full textYavas, A., M. van Putten, E. Niks, and A. Aartsma-Rus. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S75—S76. http://dx.doi.org/10.1016/j.nmd.2021.07.112.
Full textMantuano, P., B. Boccanegra, F. Sanarica, E. Conte, A. Mele, M. De Bellis, O. Cappellari, and A. De Luca. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S73. http://dx.doi.org/10.1016/j.nmd.2021.07.105.
Full textKreher, N., X. Li, M. Kheirabadi, K. Kamer, P. Dougherty, W. Lian, C. Waters, et al. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S74. http://dx.doi.org/10.1016/j.nmd.2021.07.106.
Full textEngelbeen, S., C. Tanganyika-de Winter, D. Van De Vijver, M. Holierhoek, A. Yavas, S. Kooijman, A. Aartsma-Rus, and M. van Putten. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S73. http://dx.doi.org/10.1016/j.nmd.2021.07.103.
Full textSchneider, A., S. Jirka, C. Tanganyika-de Winter, H. Mei, J. Boom, and A. Aartsma-Rus. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S75. http://dx.doi.org/10.1016/j.nmd.2021.07.111.
Full textCreisméas, A., C. Gazaille, A. Bourdon, A. Lafoux, M. Allais, V. Le Razavet, M. Ledevin, et al. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S76. http://dx.doi.org/10.1016/j.nmd.2021.07.114.
Full textvan Putten, M., C. Tanganyika-de Winter, K. Putker, S. Engelbeen, D. Van de Vijver, M. Verhaeg, M. Overzier, and A. Aartsma-Rus. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S74. http://dx.doi.org/10.1016/j.nmd.2021.07.107.
Full textMantuano, P., B. Boccanegra, E. Bresciani, F. Sanarica, A. Mele, M. De Bellis, O. Cappellari, et al. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S77. http://dx.doi.org/10.1016/j.nmd.2021.07.117.
Full textMorin, A., O. Petrova, M. Petkova, T. Tensorer, T. Manoliu, I. Richard, L. Garcia, et al. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S72—S73. http://dx.doi.org/10.1016/j.nmd.2021.07.102.
Full textKim, S., N. Buss, C. Qiao, H. Patel, L. Yang, K. Elliott, R. Qian, L. Ye, M. Fiscella, and O. Danos. "DMD – ANIMAL MODELS." Neuromuscular Disorders 31 (October 2021): S76. http://dx.doi.org/10.1016/j.nmd.2021.07.115.
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