Academic literature on the topic 'Drug therapy'

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Journal articles on the topic "Drug therapy"

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Santos, Zélia Maria de Sousa Araújo, Helder de Pádua Lima, Flávia Braga de Oliveira, Jamilly Silva Vieira, Natasha Marques Frota, and Jennara Candido do Nascimento. "User's adherence to hypertensive drug therapy." Rev Rene 14, no. 1 (2013): 11–22. http://dx.doi.org/10.15253/2175-6783.2013000100003.

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The low treatment adherence is one of the major factors for the lack of blood pressure control and risk for cardiovascular diseases. We aimed to analyze the hypertensive user's adherence to drug therapy. A descriptive study carried out with 400 hypertensive users, from May to August 2010, through interviews. Most interviewees were female (67.2%), aged over 60 (54.3%) and with brown skin (57.4%). 326 (81.5%) users were making regular use of medicine with a predominance of those with over 10 years of diagnosis (33.5%), those with up to 5 years of treatment (31.0%), and those who received the complete medication provided by SUS (39.2%). The knowledge on the types of antihypertensive drugs and the daily frequency of medication prevailed regardless the regularity of medication, the same happened regarding the lack of knowledge on side effects, to the discomforts caused and the complexity of drug therapy. We concluded that the treatment adherence prevailed in most users.
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Borba, Anna Karla de Oliveira Tito, Ana Paula de Oliveira Marques, Márcia Carrera Campos Leal, Roberta de Souza Pereira da Silva Ramos, Ana Clara Carvalho Gonçalves Guerra, and Thaysa Melo Caldas. "Adherence to drug therapy in diabetic elderly." Rev Rene 14, no. 2 (2013): 394–404. http://dx.doi.org/10.15253/2175-6783.20130002000018.

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Sectional and observational study, which investigates access to medicine, socioeconomic and demographic profiles and their association with drug adherence to drug therapy in diabetic elderly assisted in a gerontogeriatric public service. Data were collected from 126 participants through structured interviews between February and September 2011. The results reveal that 47.6% of the elderly received their drug from the public health system. The elderly women prevailed, in more than 9 years of studies, retired and income of 1-2 minimum wages. As for drug adherence, 93.7% reported using their medication regularly, but only 52.4% were considered compliant under the Test of Batalha. There was no association between socioeconomic and demographic variables and self-reported adherence. It is necessary to invest in educational initiatives targeted to the elderly patients to promote adherence to therapy.
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MRPhamiS, Ian Tritschler. "Drug therapy." Nursing Standard 8, no. 8 (November 10, 1993): 52. http://dx.doi.org/10.7748/ns.8.8.52.s65.

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&NA;. "DRUG THERAPY." American Journal of Nursing 97, no. 4 (April 1997): 10. http://dx.doi.org/10.1097/00000446-199704000-00006.

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Iseman, M. D. "DRUG THERAPY." Pediatric Infectious Disease Journal 13, no. 5 (May 1994): 426. http://dx.doi.org/10.1097/00006454-199405000-00026.

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Rochon, P. A., and J. H. Gurwitz. "Drug therapy." Lancet 346, no. 8966 (July 1995): 32–36. http://dx.doi.org/10.1016/s0140-6736(95)92656-9.

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Tank, D. "Drug therapy." International Journal of Gynecology & Obstetrics 70 (2000): D14—D15. http://dx.doi.org/10.1016/s0020-7292(00)82534-5.

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Buskila, Dan. "Drug therapy." Best Practice & Research Clinical Rheumatology 13, no. 3 (September 1999): 479–85. http://dx.doi.org/10.1053/berh.1999.0038.

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OʼDONNELL, JAMES. "DRUG THERAPY." Nursing 24, no. 3 (March 1994): 46–48. http://dx.doi.org/10.1097/00152193-199403000-00020.

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Davis, George A., and Mary H. H. Chandler. "DRUG THERAPY AND DRUG INTERACTIONS." Oral and Maxillofacial Surgery Clinics of North America 8, no. 2 (May 1996): 245–63. http://dx.doi.org/10.1016/s1042-3699(20)30897-9.

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Dissertations / Theses on the topic "Drug therapy"

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O'Callaghan, Christopher. "Aerosolised drug therapy in infancy." Thesis, University of Nottingham, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305089.

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Pandie, Mishal. "Drug-drug interactions between antiretrovirals and bedaquiline." Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/27401.

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Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide. People living with HIV are particularly susceptible to TB infection, and treatment of HIV-TB co-infection is challenging for multiple reasons, including potential drug-interactions. Drug-resistant TB is difficult to treat and is associated with high treatment failure rates, mainly because the antimycobacterial drugs currently available are ineffective against drug-resistant TB. Bedaquiline is a new antimycobacterial drug which has shown great promise through its excellent efficacy for treating drug-resistant TB. Being a new drug, however, potential drug interactions with antiretrovirals are a major concern. Bedaquiline is metabolized in the liver by an enzyme called cytochrome P450 3A (CYP3A). The antiretrovirals nevirapine, efavirenz, and lopinavir/ritonavir (LPV/r) can affect the activity of this enzyme, and consequently affect the concentration of bedaquiline in the patient's blood. Nevirapine and efavirenz increase the activity of CYP3A, which may result in increased metabolism of bedaquiline, thus decreasing the concentration of bedaquiline, with consequent risk of treatment failure or the further development of drug-resistance. LPV/r inhibits the CYP3A enzyme, which may result in decreased bedaquiline metabolism, thus causing high concentration of bedaquiline in the blood, with consequent risk of toxicity. We conducted a pharmacokinetic study in 43 adult patients with drug-resistant TB to evaluate the drug-interactions between bedaquiline and the antiretrovirals nevirapine and LPV/r. We did serial measurements of the bedaquiline concentration in their plasma over 48 hours, and compared these concentrations in patients who were on antiretroviral and those who were not on antiretrovirals. Our results showed that nevirapine had no significant effect on bedaquiline concentrations, while patients on LPV/r had bedaquiline concentrations 2 fold higher than patients not on antiretrovirals. We could not determine the clinical significance of this, but recommend that patients receiving LPV/r and bedaquiline in combination must be closely monitored for side-effects.
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Mathis, Leigh Ann. "Student Psychotropic Drug Use, Past Therapy Experience and Length of Therapy." TopSCHOLAR®, 2008. http://digitalcommons.wku.edu/theses/49.

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Alfahad, Mohanad Abdul-Satar Mahmood. "Pro-drug strategies for pancreatic cancer therapy." Thesis, Keele University, 2018. http://eprints.keele.ac.uk/4534/.

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Pancreatic cancer is the fourth main cancer in the western world. Currently the only chemotherapy available clinically is gemcitabine. However, gemcitabine treatment only proves effective in 23.8% of patients. Nano-structures (< 120 nm) are capable of entering the highly permeable blood capillaries which supply the rapidly growing tumours. Once inside the capillaries they accumulate and are retained in the tumour as a result of the poor lymphatic drainage. This allows for a deeper tissue penetration which is otherwise difficult to achieve. Hybrid nanoparticles with an iron oxide core covered by gold shell (HNPs) have shown great potential for anti-cancer therapies. The magnetic iron oxide cores and the surface plasmon resonance (SPR) properties of the gold surface provide the HNPs with the capabilities of diagnostic imaging and drug delivery, making them true theranostic agents. A novel prodrug of gemcitabine has been developed by a regioselective coupling of gemcitabine and lipoic acid, itself a potent antioxidant. Gemcitabine-N-lipoate (GL) was obtained in a one-pot synthesis and the optimum conditions for the reaction were established. GL prodrug loading on to the HNPs surface was confirmed and the release profile of gemcitabine from the GL-HNPs formulation was studied at pH 3.6, 5.6 and 7.4 utilising different temperature conditions (20, 37, 44 °C) using RPMI serum free media under sink conditions. The data showed the stability of the formulation at pH 7.4, 20 °C while the optimum release conditions for gemcitabine from the GL-HNPs formulation were at pH 5.6, 44 °C with the highest release of 41.1% recorded after 24 hrs. III Preliminary in vitro MTT assay together with the drug uptake study show the superior inhibitory effect of the GL-HNPs formulation on the cell viability over gemcitabine after 24 hrs which indicates faster uptake of the formulation, however the overall effect of gemcitabine is greater after 48 hrs which is mainly due to the slow release of gemcitabine from the formulation. The behaviour of the GL-HNPs formulation as a drug delivery system shows a great potential for the system to act as a theranostic tool and to overcome the significant drawbacks associated with gemcitabine.
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Morrow, D. I. J. "Novel Drug Delivery Approaches to Photodynamic Therapy." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502072.

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Yung, Bryant Chinung. "NANOPARTICLE DRUG DELIVERY SYSTEMS FOR CANCER THERAPY." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417614665.

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Zi, Hong. "Polymers for drug delivery in cancer therapy /." May be available electronically:, 2008. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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Murphy, Jennifer. "Therapy and Punishment: Negotiating Authority in the Management of Drug Addiction." Diss., Temple University Libraries, 2008. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/8969.

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Sociology
Ph.D.
Throughout the twentieth century, many behaviors previously considered criminal or immoral were instead defined as medical problems. This process is often referred to as the medicalization of deviance. Like many other behaviors once considered deviant, drug and alcohol abuse has been medicalizing, in a process that accelerated during the latter half of the twentieth century. Despite this movement along the path toward medicalization, drug use, and alcohol use to a lesser extent, are still also sanctioned and managed by the criminal justice system, resulting in a medical-legal-moral hybrid definition of these issues. Today we find instances where these two institutions overlap significantly. At the same time, their mutual involvement in defining and managing drug use is inconsistent. This research uses a qualitative research design to study how this medical-legal-moral hybrid definition of drug use and addiction is discussed and negotiated by various institutions that label and manage individuals who use drugs. I examined this issue by conducting interviews and observations in Philadelphia's Drug Treatment Court as well as in two outpatient drug treatment programs. Results indicate that individuals in both settings frame addiction as a "disease," although the definition is ambiguous and inconsistent. The court and the treatment programs use similar language and methods for assessing substance abuse and how to deal with it. Both also extend the definition of "addiction" to include aspects not directly related to the consumption of drugs or alcohol but to the "drug lifestyle" that includes selling drugs. Still, in neither location is a comprehensive, clear definition of "addiction" promoted and used consistently. This ambiguity results in an overlap of therapeutic and punitive methods to handle the individual's drug usage. In addition, both settings benefit from their interaction and cooperation in managing individuals with substance abuse problems, indicating that rather than moving toward a purely "medical" way of dealing with substance abuse, or placing the issue more firmly in the realm of the criminal justice system, the current mix of moral, criminal and medical methods of labeling and managing substance abuse problems may be more stagnant than the medicalization of deviance thesis suggests.
Temple University--Theses
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Deshauer, Dorian. "Enrichment-discontinuation designs in psychiatric drug maintenance therapy." Thesis, University of Ottawa (Canada), 2007. http://hdl.handle.net/10393/27829.

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Objective. This thesis tests the validity of a randomized controlled trial variant, the enrichment-discontinuation design (also called a randomized discontinuation design) against gold-standard classic RCT's using published trials of psychiatric drug therapy. Methods. A series of systematic reviews were conducted to identify all maintenance trials of mood stabilizers and antidepressants. Planned comparisons between enrichment discontinuation trials and gold standard classic RCT's were conducted. Finally, a sample of research literature was reviewed to identify the extent to which the limits of enrichment discontinuation trials were identified. Results. There was a non-statistically significant trend favoring drugs used in open phases vs classic RCT's. The lack of extended classic RCT's of psychiatric drugs is poorly recognized. Conclusion. Enrichment discontinuation designs dominated the evidence base supporting psychiatric drug maintenance. Bias cannot be ruled out. Limits to the design are poorly recognized in the literature. For further details, refer to the executive summary.
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Massicotte, Eric M. "Adjunctive drug therapy for treatment of experimental hydrocephalus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0011/MQ53184.pdf.

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Books on the topic "Drug therapy"

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G, Katzung Bertram, ed. Drug therapy. 2nd ed. London: Prentice-Hall International, 1991.

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G, Katzung Bertram, ed. Drug therapy. 2nd ed. Norwalk, Conn: Appleton & Lange, 1991.

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Schneeweiss, Adam. Cardiovascular drug therapy: Nitrate therapy. Berlin: Springer-Verlag, 1990.

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Khan, M. Gabriel. Cardiac Drug Therapy. Totowa, NJ: Humana Press, 2015. http://dx.doi.org/10.1007/978-1-61779-962-4.

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Schneeweiss, Adam. Cardiovascular Drug Therapy. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74617-8.

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Khan, M. Gabriel. Cardiac drug therapy. 3rd ed. London: W.B. Sanders, 1992.

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G, Barsan William, Jastremski Michael S, and Syverud Scott A, eds. Emergency drug therapy. Philadelphia: Saunders, 1991.

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Gideon, Koren, and Ito Shinya, eds. Fetal drug therapy. Philadelphia: W.B. Saunders, 1994.

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Gonsoulin, Sheryl M. Prehospital drug therapy. St. Louis: Mosby Lifeline, 1994.

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Corporation, Springhouse, ed. Cardiovascular drug therapy. Springhouse, Pa: Springhouse Corp., 1995.

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Book chapters on the topic "Drug therapy"

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Bloxham, Jill. "Drug Therapy." In Perspectives in Nursing Management and Care for Older Adults, 129–47. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-18012-6_9.

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He, Ri-Hui, and Ran Tao. "Drug Therapy." In Advances in Experimental Medicine and Biology, 219–45. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5562-1_11.

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Swerdlow, Mark, and Vittorio Ventafridda. "Drug Therapy." In Cancer Pain, 69–88. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-010-9139-8_7.

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Stock, John L. "Drug Therapy." In Osteoporosis, 173–87. Totowa, NJ: Humana Press, 1996. http://dx.doi.org/10.1007/978-1-4612-0221-9_15.

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Pastrana, R. "Drug therapy." In Back Pain, 143. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-2165-8_16.

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Swift, C. G. "Drug Therapy." In Geriatric Medicine, 299–311. London: Springer London, 1989. http://dx.doi.org/10.1007/978-1-4471-1646-2_24.

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Herrick, Ariane L., Fredrick M. Wigley, and Janet Pope. "Drug Therapy." In Raynaud’s Phenomenon, 343–68. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-52581-0_19.

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Borchert, Jill S. "Considerations with Pharmacodynamic Drug-Drug Interactions." In Oral Anticoagulation Therapy, 207–12. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-54643-8_30.

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Ieuter, Rachel C. "Pharmacokinetic Drug-Drug Interactions with Warfarin." In Oral Anticoagulation Therapy, 221–27. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-54643-8_32.

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Deutsch, Tibor, Ewart Carson, and Endre Ludwig. "Planning Drug Therapy." In Dealing with Medical Knowledge, 199–244. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4757-9951-4_8.

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Conference papers on the topic "Drug therapy"

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Bano, Dr Zaheda, Dr P. N. Amaranath, and Sk Farida. "Combination Drug Therapy versus Single Drug Therapy." In Annual International Conference on Pharmacology and Pharmaceutical Sciences. Global Science & Technology Forum (GSTF), 2014. http://dx.doi.org/10.5176/2345-783x_pharma14.49.

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Sokolov, Victor V. "First clinical results with a new drug for PDT." In Photodynamic Therapy of Cancer II. SPIE, 1995. http://dx.doi.org/10.1117/12.199168.

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Cao, Yu, and Xiangrui Chen. "Research on Drug Therapy of Atherosclerosis." In The International Conference on Biomedical Engineering and Bioinformatics. SCITEPRESS - Science and Technology Publications, 2022. http://dx.doi.org/10.5220/0011214500003443.

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Oliveira, Marcos Fernando dos Santos, Andréa Rico Cabra, Taísa Maria Mendes Matuiama Machado, Antônio Sérgio Guimarães, and Luciane Lacerda Franco Rocha Rodrigues. "Phonophoresis therapy for TMD pain control." In II INTERNATIONAL SEVEN MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/homeinternationalanais-109.

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Abstract Temporomandibular dysfunction (TMD) according to Okeson, (1998) is the term used to describe a comprehensive condition of clinical changes in the orofacial region, temporomandibular joint (TMJ) and adjacent structures, where it is most commonly observed the painful symptomatology present in the dysfunctions of the masticatory muscles and cervical muscles. A non-invasive therapeutic option for TMD control is phonophoresis, a technique that associates therapeutic ultrasound with a drug, described by Skauen and Zentner (1984), as drug movement through intact living skin and soft tissues under the influence of an ultrasonic disturbance, enabling greater spreading, penetration and absorption of the drugs used.
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Kobayashi, Kanako, Shuichi Yano, and Toshikazu Ikeda. "Adjunctive Corticosteroid Therapy For Adverse Drug Reactions Due To Antituberculous Drugs." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4913.

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Thomas, E., and F. Blotman. "SP0064 Drug therapy in fibromyalgia. a review." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.20.

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Alonso, Joan F., Miquel A. Mananas, Sergio Romero, Jordi Riba, Manel J. Barbanoj, and Dirk Hoyer. "Connectivity analysis of EEG under drug therapy." In 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2007. http://dx.doi.org/10.1109/iembs.2007.4353768.

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Katta, S., and T. Connolly. "Acute Drug-Induced Pneumonitis from Brentuximab Therapy." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1473.

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Jandhyala, Sidhartha, and Geoffrey P. Luke. "Optically Activated Oxygen-Loaded Perfluorocarbon Nanoparticles for Ultrasound-guided Radiation Therapy." In Optical Molecular Probes, Imaging and Drug Delivery. Washington, D.C.: OSA, 2017. http://dx.doi.org/10.1364/omp.2017.omw3d.7.

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Dubal, Jigar, and Lucia Florescu. "Cherenkov Light-based Dosimetry for Molecular Radiation Therapy of the Thyroid." In Optical Molecular Probes, Imaging and Drug Delivery. Washington, D.C.: Optica Publishing Group, 2023. http://dx.doi.org/10.1364/omp.2023.otu2e.4.

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We perform Monte Carlo simulations using clinical CT geometries to in-vestigate Cherenkov light emission in molecular radiation therapy of hyperthyroidism and papillary thyroid carcinoma and demonstrate that Cherenkov-light based dosimetry could be feasible.
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Reports on the topic "Drug therapy"

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yazheng, Zhu. Advances in Drug Therapy for Breast Cancer. ResearchHub Technologies, Inc., April 2024. http://dx.doi.org/10.55277/researchhub.3uq5vya7.

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada410175.

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Fort Belvoir, VA: Defense Technical Information Center, July 2004. http://dx.doi.org/10.21236/ada435264.

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Esenaliev, Rinat O. Novel Drug Delivery Technique for Breast Cancer Therapy. Fort Belvoir, VA: Defense Technical Information Center, July 2003. http://dx.doi.org/10.21236/ada418735.

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Fink, Howard A., Roderick MacDonald, Mary L. Forte, Christina E. Rosebush, Kristine E. Ensrud, John T. Schousboe, Victoria A. Nelson, et al. Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), April 2019. http://dx.doi.org/10.23970/ahrqepccer218.

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Mourant, J., I. Biglo, and T. Johnson. Measurement of photodynamic therapy drug concentrations in a tissue. Office of Scientific and Technical Information (OSTI), September 1996. http://dx.doi.org/10.2172/374406.

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Foroozesh, Maryam. A Drug Discovery Partnership for Personalized Breast Cancer Therapy. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada568389.

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Foroozesh, Maryam, Thomas Weise, Jayalakshmi Sridhar, Barbara Beckman, Matthew Burow, Frank Jones, and Cheryl Stevens. A Drug Discovery Partnership for Personalized Breast Cancer Therapy. Fort Belvoir, VA: Defense Technical Information Center, September 2013. http://dx.doi.org/10.21236/ada590425.

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Donahue, Katrina E., Gerald Gartlehner, Elizabeth R. Schulman, Beth Jonas, Emmanuel Coker-Schwimmer, Sheila V. Patel, Rachel Palmieri Weber, Kathleen N. Lohr, Carla Bann, and Meera Viswanathan. Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update. Agency for Healthcare Research and Quality (AHRQ), July 2018. http://dx.doi.org/10.23970/ahrqepccer211.

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Hudachek, Susan F. Predicting the Toxicity of Adjuvant Breast Cancer Drug Combination Therapy. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada574076.

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