Dissertations / Theses on the topic 'Drug delivery micellar systems'
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Mishra, Kaushik. "Folate Receptor-Targeted Polymeric Micellar Nanocarriers as Drug Delivery Systems." University of Akron / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=akron1629218263972419.
Full textRosenbaum, Erik. "Optical characterization of potential drugs and drug delivery systems." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-40177.
Full textSutton, Damon Michael. "PH SENSITIVE RNA AND DRUG DELIVERY SYSTEMS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=case1179847644.
Full textZeng, Yi. "Stable Polymer Micelle Systems as Anti-cancer Drug Delivery Carriers." Diss., CLICK HERE for online access, 2005. http://contentdm.lib.byu.edu/ETD/image/etd841.pdf.
Full textHans, Meredith L. Lowman Anthony M. "Synthesis, characterization, and application of biodegradable polymeric prodrug micelles for long-term drug delivery /." Philadelphia, Pa. : Drexel University, 2006. http://dspace.library.drexel.edu/handle/1860/741.
Full textSCIALABBA, Cinzia. "Nanosistemi polimerici per la veicolazione di farmaci antitumorali o attivi sul sistema nervoso centrale." Doctoral thesis, Università degli Studi di Palermo, 2014. http://hdl.handle.net/10447/90804.
Full textPonta, Andrei G. "POLYMER MICELLES FOR TUNABLE DRUG RELEASE AND ENHANCED ANTITUMOR EFFICACY." UKnowledge, 2013. http://uknowledge.uky.edu/pharmacy_etds/26.
Full textTeng, Yue. "Solubilization and release studies of small molecules in polymeric micelles /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.
Full textRaj, April. "Mechanistic studies to evaluate the targeting specificity of novel RGD Micelles to the αVβ3 integrin receptor." Scholarly Commons, 2012. https://scholarlycommons.pacific.edu/uop_etds/830.
Full textStaples, Bryant J. "Pharmacokinetics of Ultrasonically-Released, Micelle-Encapsulated Doxorubicin in the Rat Model and its Effect on Tumor Growth." Diss., CLICK HERE for online access, 2007. http://contentdm.lib.byu.edu/ETD/image/etd1844.pdf.
Full textVarvarenko, S. M., N. V. Puzko, A. S. Voronov, I. A. Dron, I. T. Tarnavchyk, N. G. Nosova, V. Ja Samaryk, and S. A. Voronov. "Colloidal and Chemical Properties of Polyesters Based on Glutamic Acid and Diols of Different Nature." Thesis, Sumy State University, 2012. http://essuir.sumdu.edu.ua/handle/123456789/35074.
Full textShen, Steve I. "Arg-Gly-Asp (RGD) conjugated aliphatic acids as micellar drug carrier for targeted drug delivery." Scholarly Commons, 2004. https://scholarlycommons.pacific.edu/uop_etds/2641.
Full textKetkar, Amol Sharad. "Polymeric drug delivery systems /." The Ohio State University, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487859879937796.
Full textZaher, Amir. "Remotely controlled drug delivery systems." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/57611.
Full textApplied Science, Faculty of
Engineering, School of (Okanagan)
Graduate
Squire, Marie A. "Protein-based drug delivery systems." Thesis, University of Canterbury. Chemistry, 2004. http://hdl.handle.net/10092/6518.
Full textMuldoon, B. M. "Mucoadhesive systems for drug delivery." Thesis, Queen's University Belfast, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268336.
Full textAllen, Rosamund Elizabeth. "Liposomes as drug delivery systems." Thesis, University of Essex, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.352982.
Full textQin, Jian. "Environment-Sensitive Multifunctional Drug Delivery Systems." Doctoral thesis, KTH, Funktionella material, FNM, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-12053.
Full textQC20100722
Qin, Jian. "Nanoparticles for multifunctional drug delivery systems." Licentiate thesis, Stockholm : Kemi, Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4369.
Full textCampbell, K. C. "Novel systems for transdermal drug delivery." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368758.
Full textLee, Antony James. "Mathematical modelling of drug delivery systems." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309563.
Full textUdo-Chijioke, Onyinyechi. "Aquasomes : multilayered nanoparticular drug delivery systems." Thesis, Aston University, 2016. http://publications.aston.ac.uk/33399/.
Full textWeaver, Richard. "Polyammonium conjugates as drug delivery systems." Thesis, University of Leicester, 1995. http://hdl.handle.net/2381/33980.
Full textOgden, Dorothy. "Modifiable Hyperbranched Polyester Drug Delivery Systems." Wright State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1316178520.
Full textFei, Dan. "Biodegradable polyanhydrides as drug delivery systems." Thesis, Aston University, 2003. http://publications.aston.ac.uk/10949/.
Full textLiu, Weipeng. "Biopolymer-based ocular drug delivery systems." Diss., Connect to online resource - MSU authorized users, 2008.
Find full textSodunke, Oluyomi. "Polymeric Micellar Network Derived from the Polymerization of Bicontiuous Microemulsion for Oral Drug Delivery Application." University of Akron / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=akron1429738431.
Full textChopra, Poonam. "Ocular Iontophoresis of Nanocarriers for Sustained Drug Delivery to the Eye." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1353951512.
Full textCervantes, Martínez Claudia Violeta. "Porous and hybrid silica from biocompatible systems : application to drug release." Electronic Thesis or Diss., Université de Lorraine, 2019. http://www.theses.fr/2019LORR0295.
Full textThe objective of this work focuses on the preparation of porous, hybrid silicate materials doped with an active ingredient, based on biocompatible components for pharmaceutical applications, as drug delivery systems. The motivation for this study is related to the need to meet the growing demand for more effective drugs. The first point of interest of this study concerns the compounds used which are biocompatible, low-cost, and which are good candidates for the formation of mesostructured materials. The surfactant used was Kolliphor EL (KEL) and the oils were Miglyol 812N (Mig), and Isopropyl Myristate (IM). The active ingredient Ketoprofen (KTP) was chosen as the molecule model for the evaluation of release assays. Finally, HeLa cells, a cancer cell, were used to assess the toxicity of the synthesized materials. The first chapter is devoted to the state of the art of molecular structures based on non-ionic surfactants as KEL. Then, the main publications relating to porous and hybrid materials as drug carriers are summarized. At the end of this chapter, the kinetic release models and corresponding equations are presented. The second chapter brings together the methods and characterization techniques used. The third chapter studies the phase behaviour of the KEL/water binary system studied in this work and is described. The different 1- and 2-phase domains were determined and characterized by visual inspection, using polarized light optical microscopy and liquid crystal structures by SAXS. Then, the influence of oil addition in the KEL/water system was studied at 25°C. Ternary phase diagrams were established with Miglyol (Mig) and Isopropyl Myristate (IM). From these Mig and IM-based systems, mesoporous materials were prepared. With optimized synthesis conditions, the mesoporous network was structured in both cases. In the fourth chapter the influence of the addition of a block copolymer, the P123 in the KEL/water system is reported and the phase diagram is present. It evaluated the synergy of the two surfactants to form micelles and liquid crystals. Then, the effect of the addition of P123 micelles in Isopropyl Myristate based fine emulsions on the characteristics of the porous materials thus prepared using different P123 micelle contents, it is possible to vary the degree of porosity of the materials. For emulsion (Em)/micelle P123 proportions less than 50/50, mesoporous silicas with two pore sizes are obtained. When the Em/P123 ratio increases, it is possible to control the porosity of the materials. The fifth chapter concerns the study of the encapsulation of KTP in different systems and its release. Concentrated emulsions as well as hybrid materials based on micellar solutions and fine emulsions have been selected. Release studies were performed with a PbS solution at different pH levels: 7.4; 1.2 and 4.6. The results showed that, under neutral conditions, the KTP released by hybrid materials based on micellar solutions reaches 38% after 24 hours and the pH effect increases the amount of KTP released. Then, the release into a receptor solution with different concentrations of P123 was studied. The results show that the amount of KTP released in the presence of 5% P123, reach 65% after 24 hours. In the last part, the toxicity of doped materials and hybrid systems was assessed. The results show that the silica matrix protects the cells because cell viability is increased, from 64 to almost 80% with hybrid materials
Jørgensen, Lene. "Lipid based drug delivery systems for parenteral delivery of proteins /." Cph. : Department of Pharmaceutics, the Danish University of Pharmaceutical Sciences, 2004. http://www.dfh.dk/phd/defences/lenejoergensen.htm.
Full textZhang, Ling Centre for Advanced Macromolecular Design Faculty of Engineering UNSW. "Well defined stimuli-responsive cross-linked micelles as biocompatible drug/gene delivery system from RAFT polymerization." Publisher:University of New South Wales. Centre for Advanced Macromolecular Design, 2009. http://handle.unsw.edu.au/1959.4/43362.
Full textSong, Lin. "STUDIES OF SOLUBILIZATION OF POORLY WATER-SOLUBLE DRUGS DURING IN VITRO LIPOLYSIS OF A MODEL LIPID-BASED DRUG DELIVERY SYSTEM AND IN MIXED MICELLES." UKnowledge, 2011. http://uknowledge.uky.edu/pharmacy_etds/1.
Full textBaki, Mert. "Bone Marrow Targeted Liposomal Drug Delivery Systems." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613251/index.pdf.
Full text(SDF-1&alpha
) upon bone marrow transplantation (BMT). There is a need for increasing homing efficiency after BMT since only 10-15% of the transplanted cells can home to their own niches and a limited amount of donor marrow can be transplanted. In this study, we aimed to develop and characterize bone marrow targeted liposomal SDF-1&alpha
delivery system prepared by extrusion method. Alendronate conjugation was chosen to target the liposomes to bone marrow microenvironment, particularly the endosteal niche. Optimization studies were conducted with the model protein (
Zaid, Alkilani Ahlam. "Polymeric microneedle systems for transdermal drug delivery." Thesis, Queen's University Belfast, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603301.
Full textLawlor, Michelle S. "Rheological characterisation of bioadhesive drug delivery systems." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326370.
Full textBerwick, James Miles. "Surface-engineered biomimetic systems for drug delivery." Thesis, University of Nottingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416292.
Full textZhang, Huizhen. "Liposome drug delivery systems for anticancer agents." Scholarly Commons, 2008. https://scholarlycommons.pacific.edu/uop_etds/711.
Full textMcMillan, Hannah Louise. "Sustained release biodegradable ocular drug delivery systems." Thesis, Queen's University Belfast, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678216.
Full textHe, Xingyu. "Long-term Light-activated Drug Delivery Systems." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1613752062550859.
Full textHuang, Tien-Lu. "Oscillating Aqueous Gels as Drug Delivery Systems." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1366066532.
Full textYung, Bryant Chinung. "NANOPARTICLE DRUG DELIVERY SYSTEMS FOR CANCER THERAPY." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417614665.
Full textSenderoff, Richard I. "Development of fibrin-based drug delivery systems /." The Ohio State University, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487677267728699.
Full textApps, MIchael Garry. "Platinum anticancer drugs and drug delivery systems." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/14409.
Full textChia, Leonard Sze Onn. "Investigating controlled release pulmonary drug delivery systems." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/273209.
Full textGiglio, Valentina. "Biofunctionalized systems for drug discovery and delivery." Doctoral thesis, Università di Catania, 2016. http://hdl.handle.net/10761/3893.
Full textAl-Kassas, Raida. "Design of particulate delivery systems." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239000.
Full textZderic, Vesna. "Ultrasound-enhanced ocular drug delivery /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/8085.
Full textLungare, Shital. "Development of novel delivery systems for nose-to-brain drug delivery." Thesis, Aston University, 2017. http://publications.aston.ac.uk/37491/.
Full textYang, Xiaojuan. "Development of Nanoparticle Systems for Therapeutic Drug Delivery." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1248972068.
Full textPark, Jung-Hwan. "Polymeric microneedles for transdermal drug delivery." Diss., Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-06072004-131324/unrestricted/park%5Fjung-hwan%5F200405%5Fphd.pdf.
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