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Relevant bibliographies by topics / Drosophila melanogaster dopamine transporter

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Journal articles

Academic literature on the topic 'Drosophila melanogaster dopamine transporter'

Author: Grafiati

Published: 6 September 2023

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Journal articles on the topic "Drosophila melanogaster dopamine transporter"

1

Pugh, Ciara Frances, Brian Thomas DeVree, Solveig Gaarde Schmidt, and Claus Juul Loland. "Pharmacological Characterization of Purified Full-Length Dopamine Transporter from Drosophila melanogaster." Cells 11, no. 23 (2022): 3811. http://dx.doi.org/10.3390/cells11233811.

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The dopamine transporter (DAT) is a member of the neurotransmitter:sodium symporter (NSS) family, mediating the sodium-driven reuptake of dopamine from the extracellular space thereby terminating dopaminergic neurotransmission. Our current structural understanding of DAT is derived from the resolutions of DAT from Drosophila melanogaster (dDAT). Despite extensive structural studies of purified dDAT in complex with a variety of antidepressants, psychostimulants and its endogenous substrate, dopamine, the molecular pharmacology of purified, full length dDAT is yet to be elucidated. In this study

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2

Góral, Izabella, Kamil Łątka, and Marek Bajda. "Structure Modeling of the Norepinephrine Transporter." Biomolecules 10, no. 1 (2020): 102. http://dx.doi.org/10.3390/biom10010102.

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The norepinephrine transporter (NET) is one of the monoamine transporters. Its X-ray crystal structure has not been obtained yet. Inhibitors of human NET (hNET) play a major role in the treatment of many central and peripheral nervous system diseases. In this study, we focused on the spatial structure of a NET constructed by homology modeling on Drosophila melanogaster dopamine transporter templates. We further examined molecular construction of primary binding pocket (S1) together with secondary binding site (S2) and extracellular loop 4 (EL4). The next stage involved docking of transporter i

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3

Filošević Vujnović, Ana, Katarina Jović, Emanuel Pištan, and Rozi Andretić Waldowski. "Influence of Dopamine on Fluorescent Advanced Glycation End Products Formation Using Drosophila melanogaster." Biomolecules 11, no. 3 (2021): 453. http://dx.doi.org/10.3390/biom11030453.

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Non-enzymatic glycation and covalent modification of proteins leads to Advanced Glycation End products (AGEs). AGEs are biomarkers of aging and neurodegenerative disease, and can be induced by impaired neuronal signaling. The objective of this study was to investigate if manipulation of dopamine (DA) in vitro using the model protein, bovine serum albumin (BSA), and in vivo using the model organism Drosophila melanogaster, influences fluorescent AGEs (fAGEs) formation as an indicator of dopamine-induced oxidation events. DA inhibited fAGEs-BSA synthesis in vitro, suggesting an anti-oxidative ef

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4

Shin, Mimi, and B. Jill Venton. "(Digital Presentation) In Vivo Electrochemical Measurement of Dopamine in Adult Drosophila Mushroom Body." ECS Meeting Abstracts MA2022-01, no. 53 (2022): 2197. http://dx.doi.org/10.1149/ma2022-01532197mtgabs.

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Dopamine is a neuromodulator that is secreted to the synapse to relay chemical signals to target neurons. Abnormal levels of dopamine release leads to various neurodegenerative diseases. Therefore, measuring dopamine is essential to understand how dopamine is regulated under normal and pathological conditions. Drosophila melanogaster, the fruit fly, is an ideal model system for studying fundamental neurological processes and diseases because of the availability of sophisticated genetic tools and well conserved neurological processes between mammals and flies. Majority of neuroscience studies i

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5

Myers, Jennifer L., Maria Porter, Nicholas Narwold, Krishna Bhat, Brigitte Dauwalder, and Gregg Roman. "Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis." International Journal of Molecular Sciences 22, no. 23 (2021): 12967. http://dx.doi.org/10.3390/ijms222312967.

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Drosophila’s white gene encodes an ATP-binding cassette G-subfamily (ABCG) half-transporter. White is closely related to mammalian ABCG family members that function in cholesterol efflux. Mutants of white have several behavioral phenotypes that are independent of visual defects. This study characterizes a novel defect of white mutants in the acquisition of olfactory memory using the aversive olfactory conditioning paradigm. The w1118 mutants learned slower than wildtype controls, yet with additional training, they reached wildtype levels of performance. The w1118 learning phenotype is also fou

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6

Hamilton, P. J., N. G. Campbell, S. Sharma, et al. "Drosophila melanogaster: a novel animal model for the behavioral characterization of autism-associated mutations in the dopamine transporter gene." Molecular Psychiatry 18, no. 12 (2013): 1235. http://dx.doi.org/10.1038/mp.2013.157.

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7

Makos, Monique A., Kyung-An Han, Michael L. Heien, and Andrew G. Ewing. "Using in Vivo Electrochemistry To Study the Physiological Effects of Cocaine and Other Stimulants on the Drosophila melanogaster Dopamine Transporter." ACS Chemical Neuroscience 1, no. 1 (2009): 74–83. http://dx.doi.org/10.1021/cn900017w.

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8

Neckameyer, Wendi S., Stacey Woodrome, Bridgette Holt, and Adam Mayer. "Dopamine and senescence in Drosophila melanogaster☆." Neurobiology of Aging 21, no. 1 (2000): 145–52. http://dx.doi.org/10.1016/s0197-4580(99)00109-8.

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9

Giang, Thomas, Steffen Rauchfuss, Maite Ogueta, and Henrike Scholz. "The Serotonin Transporter Expression in Drosophila melanogaster." Journal of Neurogenetics 25, no. 1-2 (2011): 17–26. http://dx.doi.org/10.3109/01677063.2011.553002.

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10

Southon, A., A. Farlow, M. Norgate, R. Burke, and J. Camakaris. "Malvolio is a copper transporter in Drosophila melanogaster." Journal of Experimental Biology 211, no. 5 (2008): 709–16. http://dx.doi.org/10.1242/jeb.014159.

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