Dissertations / Theses on the topic 'Drag showt'
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Kaminski, Elizabeth Ann. "Listening to drag music, performance, and the construction of oppositional culture /." Connect to this title online, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1060196344.
Full textTitle from PDF t.p. (viewed on Apr. 30, 2006). Advisor: Vincent Roscigno, Dept. of Sociology. Includes vita. Includes bibliographical references (p. 138-150).
Villanueva, Jordán Iván. "“You better werk.” Camp representations of Rupaul’s Drag Race in Spanish subtitles." Consortium Érudit, 2015. http://hdl.handle.net/10757/615516.
Full textCondragulations, fierce, realness, werk or «Shante, you stay» are only some of the expressions from the contestants’ lexicon of RuPaul’s Drag Race (RPDR), a popular reality television show that started airing in 2009 in the USA. Through an academic lens, the study of this type of expression was anecdotally called “lavender linguistics,” during the first explorations of the sexual minorities’ ways of talking. Since then and till now, concepts related to gender, sexuality, and the works of representation have influenced both linguistics and Translation Studies, which in turn has led to critical perspectives on translation, identity transfer, acculturation and, of course, the way language works. This paper begins by briefly referring to drag queens living in Lima, Peru, and how they have changed the way they talk to each other and about themselves. As will be argued, a cultural product such as RPDR and the necessary interlingual subtitling into Spanish –commercial or fan-made– have been influencing their linguistic engagement. Further on, the concepts of camp and camp talk will be presented as they were first introduced to Translation Studies with the work of Keith Harvey during the late 1990’s. Camp representations will be then analyzed in commercial and fan-made subtitles to reveal the semiotic and pragmatic constraints resulting from cultural-specific gay identities. From this first approach, new inquiries on audiovisual translations in general and identity acculturation in particular will be proposed.
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Gilburt, Simon John Arthur. "Psychopharmacological aspects of short-term information processing." Thesis, University of Leeds, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277353.
Full textSong, Dae Hyun. "Pre-Production, Production and Post-Production on Short Film "Draw Me Invisible"." Thesis, The University of Arizona, 2014. http://hdl.handle.net/10150/321962.
Full textWuitschik, Georg. "Oxetanes in drug discovery /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17929.
Full textPetersson, Maria. "Short- and long-term cardiovascular and behavioural effects of oxytocin : mechanisms involved and influence of female steroid hormones /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3503-3.
Full textUllman, Carl Fredrik Michael. "Measuring and increasing productivity in drug discovery /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17877.
Full textBurgess, John Robert Martin E. Davis. "Efficacy of long-term and short-term residential substance abuse treatment modalities." Auburn, Ala., 2005. http://repo.lib.auburn.edu/2005%20Fall/Thesis/BURGESS_JOHN_18.pdf.
Full textNebel, Sibylle F. "The role of DNA mismatch repair in drug resistance /." [S.l.] : [s.n.], 1998. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=12553.
Full textGengler, Malou. "Reductively degradable poly(ethylene glycol) nanoparticles for intracellular drug delivery /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17501.
Full textAaro, Martina. "Polypharmacy and Inappropriate Drug Use among Elderly Patients admitted to a Short-Term Nursing Home in Örebro." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-55169.
Full textGonzalez, Raul. "The Paced Auditory Serial Addition Test (PASAT) as a measure of working memory : modified scoring guidelines, normative data, and validation /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2004. http://wwwlib.umi.com/cr/ucsd/fullcit?p3130416.
Full textVugler, Alexander David. "Predicting anti-arthritic drug effects in collagen-induced arthritis using short-term mechanistic models of collagen II immunity." Thesis, Open University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494617.
Full textvan, der Westhuizen Jos. "Biological applications, visualizations, and extensions of the long short-term memory network." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/287476.
Full textBecker, Benjamin [Verfasser]. "Die Zulässigkeit von Hinauskündigungsklauseln nach freiem Ermessen im Gesellschaftsvertrag : Zugleich eine Besprechung von Russian Roulette-, Texan Shoot Out- und Drag-along-Klauseln / Benjamin Becker." Frankfurt : Peter Lang GmbH, Internationaler Verlag der Wissenschaften, 2012. http://d-nb.info/1042586047/34.
Full textKessler, Ulrich. "Random synthesis and biological characterization of nucleoside analogs - new perspectives for drug discovery /." [S.l.] : [s.n.], 2000. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13592.
Full textEnz, Michael J. "Estimates of first-mover advantages in markets with relatively short product life cycles : an examination of the DRAM industry /." view abstract or download file of text, 2003. http://wwwlib.umi.com/cr/uoregon/fullcit?p3095243.
Full textTypescript. Includes vita and abstract. Includes bibliographical references (leaves 91-96). Also available for download via the World Wide Web; free to University of Oregon users.
Bolling-Sternevald, Elisabeth. "Functional Dyspepsia : Symptoms and Response to Omeprazole in the Short Term." Doctoral thesis, Linköping : Univ, 2003. http://www.ep.liu.se/diss/med/07/92/index.html.
Full textMeinel, Lorenz. "Engineering of bone and cartilage like tissue at the interface of drug delivery and biomaterials." Zürich : ETH, Eidgenössische Technische Hochschule Zürich, Department of Chemistry and Applied Biosciences, 2006. http://e-collection.ethbib.ethz.ch/show?type=habil&nr=25.
Full textVurma-Rapp, Ulrike Angelika Susanne. "Resistenz von "Pseudomonas aeruginosa" gegen Betalaktam-Antibiotika : Epidemiologie und molekularbiologische Grundlagen /." Zürich : Juris Druck + Verl. Zürich, 1990. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=9106.
Full textFinkenzeller, Cornelia [Verfasser], and Ursula [Akademischer Betreuer] Zimber-Strobl. "Patients' acute lymphoblastic leukemia cells show heterogeneous growth behavior and drug sensitivity in vivo / Cornelia Finkenzeller ; Betreuer: Ursula Zimber-Strobl." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1126407003/34.
Full textNepolo, Ester Ndahekelekwa. "Effects of treatment compliance on treatment outcomes for pulmonary tuberculosis patients on Directly Observed Treatment-short Course in Windhoek District, Namibia." University of the Western Cape, 2016. http://hdl.handle.net/11394/4908.
Full textTuberculosis (TB) is a major health problem worldwide, with an estimated 9 million new cases accounting for an estimated 1.5 million deaths in 2012. Non-compliance with TB treatment has become a major barrier to achieving global TB control targets. Namibia is one of the worst affected countries in Africa with a high case notification rate (CNR) of all forms of TB and relatively low treatment success rate compared to the WHO targets. The study aimed at investigating TB treatment compliance and measuring its association to patient characteristics and treatment outcomes, in determining the effects of compliance on treatment outcomes in Windhoek District. This information is crucial for TB programme management and development of targeted strategies. A quantitative observational analytic study using a retrospective cohort design was adopted. New adult Pulmonary Tuberculosis (PTB) patients treated under DOTS in Windhoek District between 1st January 2013 and 31st December 2013 were included in the study based on specified criteria. Data was collected from the patients TB treatment cards using an extraction tool. Selection and information bias was eliminated by using clearly defined inclusion and exclusion criteria using a pre-tested standardised tool. Statistical analysis using descriptive and analytic statistics was done using Epi Info 7 to determine compliance, treatment outcomes and to measure the associations. Overall treatment compliance (89%), initial phase compliance (97.2%) and continuation phase compliance (88.1%) were reported in the study. Age (OR=4.3 95% CI (1.72 – 9.90), p-value=<0.01) and type of area (OR=0.02 95% CI (1.00 – 1.13), p-value=0.05) were associated with compliance in the continuation phase. Overall, type of area (OR=0.03 95% CI (0.00 – 0.91), p-value=0.04) remains associated with treatment compliance. Treatment success is reported among 86.1% of patients. Poor treatment outcomes are associated with non-compliance in the initial phase ( =49.98, p-value=<0.01), continuation phase ( =98.81, p-value=<0.01) and overall ( =110.02, p-value=<0.01). Overall treatment compliance (89%) although higher than expected was lower than the WHO recommended 90% compliance. Very high compliance (97.2%) were reported in the initial phase of treatment whilst compliance was also lower than desired (88.1%) in the continuation phase. Non-compliance recorded in the continuation phase is in agreement with the literature. Age and type of area are associated with compliance as reported in the continuation phase and overall in this study is new contribution of knowledge. The findings suggest that treatment compliance is associated with treatment success in both phases of treatment and overall. Low compliance especially in the continuation phase could lead to poor treatment outcomes such as prolonged infections, relapse, high TB mortality and drug resistance leading to increased programme costs. The study concludes that non-compliance results in poor treatment outcomes highlighting the need for interventions that address compliance in all phases but specifically within the continuation phase and amongst those at risk of having reduced compliance such as those in rural areas and young adult patients aged (15 – 34 years). Recommendations to the District Management Team and TB Programme Managers include: identification of measures that promote treatment compliance; support and monitoring of TB patients’ compliance continuously; strengthening CB-DOT by increasing CB-DOT points and enhancing CB-DOT supporters’ capacity as well as strengthening record keeping as a monitoring tool to increase compliance and improve treatment outcomes.
Wyl, Viktor von. "HIV-1 drug resistance in the Swiss HIV Cohort study : epidemiology and impact on treatment of HIV-infected patients /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17726.
Full textJöhri, Stephan. "Portfolio optimization with hedge funds Conditional value at risk and conditional draw-down at risk for portfolio optimization with alternative investments /." Zürich : ETH, Eidgenössische Technische Hochschule Zürich, Department of Computer Science, 2004. http://e-collection.ethbib.ethz.ch/show?type=dipl&nr=127.
Full textAlkoles, Omar M. S. "Mechanical behaviour and fracture toughness of unfilled and short fibre filled polypropylene both drawn and undrawn. Experimental investigation the effect of fibre content and draw ratio on the mechanical properties of unfilled and short glass fibre filled polypropylene." Thesis, University of Bradford, 2011. http://hdl.handle.net/10454/5510.
Full textGao, Wenwen. "Functional profiling of rare GLP-1R variants, an important drug target gene of type 2 diabetes." Thesis, Université Paris Cité, 2020. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2572&f=24498.
Full textThe glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) is a class B G protein-coupled receptor and an important drug target in the treatment of type 2 diabetes (T2D)
Shauli, Mathulo Mathabiso. "Histopathology induced by a medicinal plant indigenous to South Africa that has shown in vitro anti-microbial activity against drug resistant strains of Mycobacterium tuberculosis." Thesis, Nelson Mandela Metropolitan University, 2015. http://hdl.handle.net/10948/3990.
Full textAlkoles, Omar M. "Mechanical behaviour and fracture toughness of unfilled and short fibre filled polypropylene both drawn and undrawn : experimental investigation of the effect of fibre content and draw ratio on the mechanical properties of unfilled and short glass fibre filled polypropylene." Thesis, University of Bradford, 2011. http://hdl.handle.net/10454/5510.
Full textMurano, Maria Cristina. "Critical Paediatric Bioethics and the Treatment of Short Stature : An Interdisciplinary Study." Thesis, Paris, EHESS, 2019. http://www.theses.fr/2019EHES0043.
Full textSeveral studies argue that there is a correlation between short stature and negative experiences, such as social discrimination, and economic disadvantage (especially for men). It is now possible to use recombinant human growth hormone (hGH) to treat children with idiopathic short stature (ISS), namely children who are shorter than average for unknown medical reasons. Critics argue that there is a lack of evidence of both psychological distress caused by short stature and the efficacy of the treatment in increasing children’s well-being. This controversy is reflected in international drug evaluations: while the Food and Drug Administration (FDA) in the US granted marketing authorisation for hGH for children with ISS in 2003, the European Medicines Agency (EMA) refused it in 2007. The research presented here had two aims: first, to identify and analyse the norms, values and assumptions about short stature and the use of hGH treatment for children with ISS, found within sociocultural, philosophical and regulatory discussions of these, and within narrated lived experiences of short stature. Second, to critically and reflectively discuss how these analyses contribute to bioethical debates on the use of hGH treatment for children with ISS. It employs what it calls a critical paediatric bioethics approach, which combines philosophical analyses with empirical methods. The first article proposes a critical understanding of medicalisation as both a concept and a phenomenon, and explores what insights such critical understanding brings to ethical discussions about hGH for children with ISS. The second article examines the arguments for and against granting marketing authorisation of hGH treatment for the indication of ISS presented in selected documents of the FDA and the EMA. The third article examines how and why attendance to lived experiences of height is needed in bioethical and biomedical discussions of hGH treatment for children with ISS. This research contributes to the ethical debate about using hGH for children with ISS, setting a critical gaze onto the social perception of short stature, highlighting some ethical challenges met by stakeholders involved at different levels, and providing new insights into how to address these ethical issues
Linke, Mats, and Tobias Saarela. "EFFEKTEN AV VIKTMANIPULERAD UTRUSTNING PÅ DRAGSKOTTSHASTIGHET OCH GREPPSTYRKA I INNEBANDY : EN SEX VECKORS STUDIE PÅ MANLIGA 17-ÅRIGA INNEBANDYSPELARE." Thesis, Högskolan i Halmstad, Biomekanik och biomedicin, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-15290.
Full textFloorball is a sport with increasing number of participants, which has not been studied extensively according to the literature. Previous studies on ice hockey and baseball have shown that training with weight manipulated equipment improved grip strength and swing speed. Other research has shown that the increased performance with dynamic resistance training rather occurs from the improvements in the neuromuscular facilitation than an increase in muscle mass. In floorball shooting velocity is considered to be an important factor of the performance. Since it has been shown in baseball that training with weight manipulated equipment can improve the bat velocity, it would be interesting to see if the same results can be found in floorball. The purpose of this study was to investigate the effect of grip strength and drag shot velocity in floorball training with a weight manipulated floorball stick. The study also investigated the relationship between grip strength and drag shot velocity. The test subjects’ subjective perception about the training method was also investigated. Thirteen 17-year-old male floorball players participated in the study. During a six weeks period the subjects used the weight manipulated equipment during 30 minutes, three times per week during their regular team practice. 40 grams lead tape was attached to the player's equipment to increase the resistance. The drag shots were filmed with a high speed camera (Casio Exilim EX-FH25) at 250 fps. The drag shot velocity was analyzed in Dartfish. To assess grip strength a hand dynamometer (Jamar - Baseline Hydraulic Hand Dynamometer)was used. The training resulted in a significant increase for the subjects’ grip strength in the lower hand on the stick (p <0,05). The study found no significant difference for the upper hand grip strength or drag shot velocity. No correlation between drag shot velocity and handgripstrength among the subjects were found. Conclusion: The results found in this study indicate that training with weight manipulated equipment can significantly improve the player’s lower hand grip strength. The results can eventually be explained by more effective fiber recruitment in the muscles. Studying floorball can contribute to increase the interest in research on floorball and increase the understanding for how dynamic resistance training can be incorporated in daily floorball practice.
Marouby, Matthieu. "Trois études de processus fractionnaires." Toulouse 3, 2010. http://thesesups.ups-tlse.fr/946/.
Full textThe first part is devoted to the simulation of the Local Time Fractional Stable Motion (LTFSM). This process, which was introduced in 2006 by Cohen and Samorodnitsky, is defined as the integration of the local time of a fractional Brownian motion with respect to a random stable measure, the randomness of both objects being defined on two independent probability spaces. Using a series representation method to simulate it, I obtain a control of the approximation. In the second part, I study processes obtained as limits of sums of micropulses, specifically focusing on behavior when "ups" and "downs" of the micropulses are not equal. Then, I generalize the processes obtained to processes with multidimensional indices. Processes obtained in this work vary from standard Brownian motions to multifractional Brownian sheets. Finally, I study a model from physic theory, a field created by charged particles randomly distributed in a hyperplan. The limit process is fractional, centered, Gaussian and in some cases well-known like fractional Brownian motion. Eventually, I study some of its characteristics, such as the number of local minima. This part raises many questions that have yet to be resolved
Bundy, Christopher. "Big in Japan the novel /." Atlanta, Ga. : Georgia State University, 2009. http://digitalarchive.gsu.edu/english_diss/41/.
Full textTitle from title page (Digital Archive@GSU, viewed July 22, 2010) Sheri Joseph, committee chair; John Holman, Josh Russell, committee members. Includes bibliographical references (p. 38).
Ghadzi, Siti Maisharah Sheikh. "Pharmacometrics Modelling in Type 2 Diabetes Mellitus : Implications on Study Design and Diabetes Disease Progression." Doctoral thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-317040.
Full textMuriithi, Paul Mutuanyingi. "A case for memory enhancement : ethical, social, legal, and policy implications for enhancing the memory." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/a-case-for-memory-enhancement-ethical-social-legal-and-policy-implications-for-enhancing-the-memory(bf11d09d-6326-49d2-8ef3-a40340471acf).html.
Full textSmith, Evan J. "Down-under drag : inside Australia's drag king and drag queen communities." Thesis, 2014. http://hdl.handle.net/1959.7/uws:36729.
Full textFeng, Z. "Development of short-chain quinones." Thesis, 2021. https://eprints.utas.edu.au/46121/1/Feng_whole_thesis.pdf.
Full textSu, Sheng-Bin, and 蘇聖斌. "Aerodynamic Drag of a Droplet with Short-Range Drop-Drop Interaction - Renormalized Droplet Theory." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/89029550054005632382.
Full text國立成功大學
航空太空工程學系
81
Renormalized droplet theory is applied to study the influence of convective flow and short range drop-drop interaction on the aerodynamic drag of a droplet. Based on the renormalized droplet theory, the influence of convective flow on the aerodynamic drag of a droplet could be decomposed into five principal mechanisms : (1) the variations in pressure of the flow field, (2) the viscous effects, (3) the variations in momentum of the flow field, (4) the thrust drag of the test droplet caused by droplet vaporization, (5) the effects of unsteadiness. It is found that for a single droplet in hot convective flow, the aerodynamic drag is decreased as the environment temperature is increased. At lower Reynolds number, the aerodynamic drag of a combustion droplet is higher than a vaporizing droplet due to the existence of the envelope flame. As the effects of drop-drop interaction are considered, the aerodynamic drag of the test droplet at lower environment temperature is increased as the number density of field droplets is increased.On the other hand, when the environment temperature is higher, the drag coefficient of the test droplet is decreased as the number density of field droplets is increased.Furthermore,according to the renormalized theory, it is found that the pressure variations dominate the drag coefficient of the test droplet, as the drop-drop interaction effects are considered. The viscous effects are further important as the number density of neighboring droplets is decreased. The variations in momentum of the flow field would produce negative effects on the drag coefficient. As to the thrust drag of the test droplet is almost negligible in our calculation.
Chistyakova, Anastasia. "Travesti Show: Performativita a Vyjednávání Genderové Identity." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-405296.
Full textTorres, Luís Henrique Magalhães Ramos. "Exploring a Siamese Neural Network Architecture for One-Shot Drug Discovery." Master's thesis, 2020. http://hdl.handle.net/10316/92189.
Full textAs redes neuronais profundas oferecem um elevado poder preditivo ao ser capazes de inferir as propriedades farmacológicas e atividades biológicas de pequenas moléculas em aplicações para descoberta de fármacos. No entanto, a quantidade de informação supervisionada disponível para treino é escassa e o passo de 'lead-optimization' apresenta um problema de 'low-data', dificultando a descoberta de novos compostos com a atividade terapêutica pretendida e respetivos análogos farmacológicos. Um requisito fundamental é a necessidade de uma grande quantidade de exemplos de treino por classe, o que nem sempre é possível em aplicações para descoberta de fármacos. Estes desafios invalidam o uso de instâncias cujas classes são desconhecidas no treino ou em dados onde o número de classes é elevado e oscila dinamicamente. O grande objetivo deste estudo é otimizar a descoberta de novos compostos partindo de um conjunto reduzido de moléculas candidatas. Assim, propomos uma arquitetura de redes neuronais paralelas implementando uma estratégia de 'one-shot learning', baseada num conjunto de redes neuronais convolucionais (CNNs) capazes de aprender a partir de um dado 'score' de semelhança entre duas moléculas devolvido por uma dada função de similaridade. Aplicando uma estratégia de 'one-shot learning', apenas necessitamos de um reduzido conjunto de instâncias por classe para treino e de um pequeno conjunto de dados e recursos computacionais para a construção de um modelo eficaz na previsão. Os resultados obtidos demonstram que o uso de um conjunto de redes neuronais convolucionais paralelas implementando uma estratégia de 'one-shot learning' conduz à obtenção de desempenhos superiores na previsão de novos compostos comparando com os modelos 'state-of-the-art'. Assim, o modelo proposto permite prever corretamente e com elevada eficácia, novos compostos e respetivos análogos farmacológicos, considerando a escassez de dados biológicos disponíveis para aplicações de descoberta e desenvolvimento de fármacos.
Deep neural networks offer a great predictive power when inferring the pharmacological properties and biological activities of small molecules in drug discovery applications. However, in the traditional drug discovery process, where supervised data is scarce, the lead-optimization step is a low-data problem, making it difficult to find molecules with the desired therapeutic activity and obtain accurate predictions for novel compounds and their pharmacological analogs. One major requirement to ensure the validity of the obtained neural network models is the need for a large number of training examples per class, which is not always feasible in drug discovery applications. This invalidates the use of instances whose classes were not considered in the training phase or in data where the number of classes is high and oscillates dynamically.The main objective of the study is to optimize the discovery of novel compounds based on a reduced set of candidate drugs. We propose a Siamese neural network architecture for one-shot classification, based on Convolutional Neural Networks (CNNs), that learns from a similarity score between two input molecules according to a given similarity function. Using a one-shot learning strategy, few instances per class are needed for training, and a small amount of data and computational resources are required to build an accurate model. The results achieved demonstrate that using a Siamese Deep Neural Network for one-shot classification leads to overall improved performance when compared to other state-of-the-art models. The proposed one-shot Siamese neural network architecture provides an accurate and reliable prediction of novel compounds considering the lack of biological data available for drug discovery tasks.
Outro - This research has been funded by the Portuguese Research Agency FCT, through D4 - Deep Drug Discovery and Deployment(CENTRO-01-0145-FEDER-029266).
Reveron, Maria Elena 1970. "Short and long-term effects of MDMA exposure in rodents : physiological, behavioral and neurochemical responses." 2006. http://hdl.handle.net/2152/13072.
Full textBenjamin, Daniela. "The effect of the short term use of Zolpidem MR on poor sleep, daily pain and depression in arthritis patients." Thesis, 2015. http://hdl.handle.net/10539/17443.
Full textIntroduction: The presence of pain during sleep causes patients with chronic daily pain, such as in Rheumatoid and Osteoarthritis, to experience insomnia, fragmented sleep and an increased number of night-time awakenings. This poor sleep results in an increased sensitivity to pain during the day. The effect of improving sleep on pain, sleep and mood after taking Zolpidem MR was the aim of this study. Methods: 11 patients from Chris Hani Baragwanath Hospital in Soweto South Africa who reported insomnia and daily pain spent 4 weeks in this crossover design, double blinded, placebo controlled study. Week 1- baseline, week 2 and 4 were Intervention weeks – either placebo or Zolpidem MR, week 3 was a Washout week. Data collected included actigraphy, McGill Pain Questionnaire, PSQI, BDI, physical activity questionnaire and daily sleep and pain diaries containing VAS scales for sleep and pain. Results: No significant changes were found in the pain or physical activity levels in any of the patients. Sleep quality, as measured by an isolated PSQI question, was improved by Zolpidem MR (p=0.0075). PSQI was decreased in the final week of the study compared to baseline (8.7 vs. 11.3, p=0.0106) and BDI was lower in week 4 than baseline (7.7 vs. 15.85, p=0.0003), BDI was also lower in week 4 compared to week 2 (7.7 vs. 12.8, p<0.05). However the changes in PSQI and BDI were a result of the order of the weeks, with patients interacting with the researcher and were not due to either Zolpidem MR or placebo. Anecdotal reports include feeling more energised and capable of living life. Conclusion: This study has shown that human interaction is an important component of treatment for insomnia and chronic pain as there is a positive effect on sleep disruption and depression.
Chen, Po-Ling, and 陳柏伶. ""Shoot first, draw the circle afterwards": Three Formality Problems in Hsia Yu's poetry." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/2wk7b7.
Full text國立清華大學
中國文學系
101
Abstract Unlike the common practice of thesis writing, this dissertation expresses my thought on Hsia Yu's poetry with the manner of self-indulging and self-destruction. It does not come with a literature review section and ground itself with theories. Even the conclusion is also very dubious. Under this kind of post-modern condition that everything is abandoned and not picked up again, I wholeheartedly investigate the poetic variation and revolution in Hsia Yu's poem and persistently write down the aesthetic blueprint and imagination in Hsia Yu's another poem. Thus, three unintended and self-enclosing pseudo-poetic terminologies appear: broken musicality, translatedness, and virtual onceness. I use these three pseudo-poetic terminologies to witness straightforwardly on the unceasing thinking about production institute of poetics behind Hsia Yu's astonishing form performance. Keywords: Hsia Yu, form, broken musicality, translatedness, virtual onceness
Provázková, Jana. "Postavení travesti show v mediální kultuře." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-392955.
Full textTrenfield, S. J., A. Goyanes, Richard Telford, D. Wilsdon, M. Rowland, S. Gaisford, and A. W. Basit. "3D printed drug products: Non-destructive dose verification using a rapid point-and-shoot approach." 2018. http://hdl.handle.net/10454/16553.
Full textThree-dimensional printing (3DP) has the potential to cause a paradigm shift in the manufacture of pharmaceuticals, enabling personalised medicines to be produced on-demand. To facilitate integration into healthcare, non-destructive characterisation techniques are required to ensure final product quality. Here, the use of process analytical technologies (PAT), including near infrared spectroscopy (NIR) and Raman confocal microscopy, were evaluated on paracetamol-loaded 3D printed cylindrical tablets composed of an acrylic polymer (Eudragit L100-55). Using a portable NIR spectrometer, a calibration model was developed, which predicted successfully drug concentration across the range of 4–40% w/w. The model demonstrated excellent linearity (R2 = 0.996) and accuracy (RMSEP = 0.63%) and results were confirmed with conventional HPLC analysis. The model maintained high accuracy for tablets of a different geometry (torus shapes), a different formulation type (oral films) and when the polymer was changed from acrylic to cellulosic (hypromellose, HPMC). Raman confocal microscopy showed a homogenous drug distribution, with paracetamol predominantly present in the amorphous form as a solid dispersion. Overall, this article is the first to report the use of a rapid ‘point-and-shoot’ approach as a non-destructive quality control method, supporting the integration of 3DP for medicine production into clinical practice.
Open Access funded by Engineering and Physical Sciences Research Council United Kingdom (EPSRC), UK for their financial support (EP/L01646X).
Chen, Minhua. "Nanotechnology for efficient delivery of short therapeutic oligonucleotides (antisense ODN and siRNA) and codelivery with chemical anticancer drugs for effective cancer therapy." 2009. http://hdl.rutgers.edu/1782.2/rucore10002600001.ETD.000051294.
Full textPeng, ChueiHsin, and 彭垂星. "The Study of Using Excel VBA to Construct Short-term Production Schedule in the Final Testing of DRAM FactoryScheduling in the Final Testing of DRAM Factory." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/25070247160831358039.
Full text中華大學
科技管理研究所
93
DRAM has the characters of high investment, high risk, high return rate, and high international competition. In Taiwan, DRAM is mainly a foundry industry. The product specification is controlled by the foreign software or hardware design house, and the market sale is limited in the overseas channels. Facing the price competitions among the Japan, Korea and etc, in addition. As the down-stream of the DRAM industry, the major profit is customers’ orders. Besides, the order profit is based on the customers’ demands of the high quality, quick delivery, and in-line process capability. The DRAM final testing factories must absorb the delay coming from the variation of pre-process, face the pressure of delivered on time or not. As a result, the production scheduling must be flexibility and mobility to meet the customers’ requests. It impacted the managers to adjust the production strategy when the non-anticipation factors (machine down, accepting the rush orders) were happened. Furthermore, it improved the production effectively and increased the competitiveness. The application of using Excel VBA to simulate the trial system is studied in this study. After simulate the process parameters and flexible scheduling, the throughput, productivity efficiency, and WIP stock quantity can be the performance targets. These targets do help the managers to plan the production scheduling, and have been practiced in one professional DRAM factory.
Lo, Kai-Hsun, and 羅凱薰. "Association of Antiplatelet Drug and Intracerebral Hemorrhage Induce Short Term Mortality – One Regional Hospital in the Northern Taiwan." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/75114276155178778732.
Full text高雄醫學大學
藥學研究所碩士在職專班
98
Intracerebral hemorrhage is cerebral vascular disease, one of the reasons for the cause of acute stroke, the second in Taiwan. In accordance with Department of Health announced the third leading cause of death accounting for 2008. In recent years has made the spontaneous intracerebral hemorrhage treatment guidelines, thus intracerebral hemorrhage as the current emphasis on the question. The prognosis of intracerebral hemorrhage depends on the hematoma location, hematoma volume, glascow coma scale, age and overall health status. The role of previous oral anti-platelet drugs therapy in the intracerebral hemorrhage still remains controversial. To understand the association between the use of antiplatelet drugs and intracerebral hemorrhage-induced short-term mortality, we conducted a retrospective case study and enrolled intracerebral hemorrhage patients who had been diagnosed with ICH from 2006 to 2009 in a regional teaching hospital of northern Taiwan. Among the 197 ICH patients in our study, 70.1% of patients did not use antiplatelet drug and the other 29.9% used antiplatelet drug. The mortality rate after ICH was 4.3% at 3 days, 6.5% at 5 days, 13% at 15 days, and 15.2% at 30 days in the group that did not use antiplatelet drug and 13.6% at 3 days, 15.3% at 5 days, 16.9% at 15 days, and 20.3% at 30 days in the group that used antiplatelet drugs. The adjusted mortality rate based on patients’ alcohol consumption, hemoglobin level, and serum creatinine level was 0.73 ( 95% CI: 0.32-1.70 ) at 3 days, 0.63 ( 95% CI: 0.27-1.49 ) at 5 days, 1.09 ( 95% CI: 0.47-2.56 ) at 15 days, and 0.99 ( 95% CI: 0.45-2.20 ) at 30 days. The study found that the use of antiplatelet drugs and short-term mortality was no correlation, so taking antiplatelet drugs did not increase the short-term mortality of intracerebral hemorrhage.
"Drug addiction and transference." Tese, MAXWELL, 2006. http://www.maxwell.lambda.ele.puc-rio.br/cgi-bin/db2www/PRG_0991.D2W/SHOW?Cont=8962:pt&Mat=&Sys=&Nr=&Fun=&CdLinPrg=pt.
Full textZinchuk, Andrii Mikolayovich, and Yevhenii Sergeevich Tregub. "The role of evidence-based medicine in providing the quality of medical care shown on the example of the Drug Service functioning." Thesis, 2016. http://repo.knmu.edu.ua/handle/123456789/13198.
Full textSilva, José Diogo Ramalho e. "Drug-induced potentially fatal arrhythmias and sudden cardiac death: a clinical perspective of long QT, short QT and Brugada syndromes." Master's thesis, 2017. https://hdl.handle.net/10216/104358.
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