Relevant bibliographies by topics / Dose intensity

Academic literature on the topic 'Dose intensity'

Author: Grafiati
Published: 9 March 2023
Last updated: 10 March 2023

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Journal articles on the topic "Dose intensity"

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Ozols, R. F., J. T. Thigpen, J. Dauplat, N. Colombo, M. J. Piccart, K. Bertelsen, L. Levin, and B. Lund. "Dose intensity." Annals of Oncology 4 (1993): S49—S56. http://dx.doi.org/10.1093/annonc/4.suppl_4.s49.

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SURBONE, ANTONELLA, and VINCENT T. DeVITA. "Dose Intensity." Annals of the New York Academy of Sciences 698, no. 1 Breast Cancer (November 1993): 279–88. http://dx.doi.org/10.1111/j.1749-6632.1993.tb17219.x.

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Coldman, A. J., and C. M. Coppin. "Calculating dose intensity." Journal of Clinical Oncology 9, no. 9 (September 1991): 1713–14. http://dx.doi.org/10.1200/jco.1991.9.9.1713.

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Piccart, M. J., L. Biganzoli, and A. Di Leo. "S34 Dose intensity and dose density." European Journal of Cancer 34 (February 1998): S8. http://dx.doi.org/10.1016/s0959-8049(97)89207-6.

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Portlock, C. S. "Dose density and dose intensity: where does CHOP go from here?" Annals of Oncology 13, no. 9 (September 2002): 1329–30. http://dx.doi.org/10.1093/annonc/mdf238.

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Tonkin, Katia, and Ian Tannock. "Dose Intensity in Chemotherapy." Journal of Clinical Oncology 3, no. 6 (June 1985): 891. http://dx.doi.org/10.1200/jco.1985.3.6.891.

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To the Editor: In a recent article, Hryniuk and Bush have established a strong correlation between dose intensity of CMF (cyclophosphamide, methotrexate, 5-fluorouracil) chemotherapy, and the rate of tumor response in patients with metastatic breast cancer. They also observed a significant correlation between rate of tumor response and median survival time (r = .66, P < .001). The authors were careful to avoid the conclusion that there was a direct correlation between dose intensity and median survival, but it is surprising that they did not examine this more important relationship directly. We have used data provided in their paper to test for correlation between median survival time and dose intensity for patients receiving CMF chemotherapy, and find little evidence for a direct relationship (r = .25, P = .27—two-tailed Student's t test). Moreover, if the studies are weighted according to the number of patients in them, the correlation coefficient is even lower (r = .14, P = .50—two-tailed Student's t test). Unfortunately, metastatic breast cancer is not cured by chemotherapy, and appropriate endpoints are those of palliation, namely quantity and quality of survival. Quality of survival cannot easily be addressed in a retrospective review, but increasing dose intensity has the capability both to improve quality of life by ameliorating symptoms of disease, and to decrease it by adding toxicity. Factors such as sites of metastases and performance status of patients are known to influence duration of survival and could mask a relationship with dose intensity. However, the data reviewed by Hryniuk and Bush do not provide evidence for a relationship between dose of chemotherapy and survival. A prospective randomized trial is in progress at our institution that addresses the relationship between dose intensity of CMF chemotherapy and both quantity and quality of survival for patients with metastatic breast cancer. In the absence of results from this and other prospective trials that address the dose-response effect of chemotherapy in palliation, one should not assume that more is better.
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Hryniak, William. "Dose Intensity…and Beyond." Cancer Investigation 22, no. 4 (January 2004): 648–49. http://dx.doi.org/10.1081/cnv-200027172.

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Meyer, R., M. Goodyear, and W. Hryniuk. "Dose intensity and lymphoma." Journal of Clinical Oncology 9, no. 8 (August 1991): 1511. http://dx.doi.org/10.1200/jco.1991.9.8.1511.

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Coldman, Andrew J., Christopher M. L. Coppin, and James H. Goldie. "Models for dose intensity." Mathematical Biosciences 92, no. 1 (November 1988): 97–113. http://dx.doi.org/10.1016/0025-5564(88)90007-7.

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Gianni, A. M., and M. J. Piccart. "Optimising chemotherapy dose density and dose intensity." European Journal of Cancer 36 (April 2000): 1–3. http://dx.doi.org/10.1016/s0959-8049(99)00258-0.

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Dissertations / Theses on the topic "Dose intensity"

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Tangboonduangjit, Puangpen. "Intensity-modulated radiation therapy dose maps the matchline effect /." Access electronically, 2006. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20060724.095712/index.html.

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FRUSCIO, ROBERT. "Somministrazione settimanale di cisplatino in pazienti con carcinoma ovarico in stadio avanzato: risultati a lungo termine di uno studio clinico randomizzato." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2010. http://hdl.handle.net/10281/13832.

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OBJECTIVES: to determine the effect of weekly administration of cisplatin as first line chemotherapy for advanced ovarian cancer patients METHODS: Patients with advanced epithelial ovarian cancer were randomly assigned (by a computer system) to the experimental dose-dense first line chemotherapic arm (Pw, cisplatin 50 mg/mq weekly x 6 cycles) or to the standard arm (Pst, cisplatin 75 mg/mq every three weeks x 6 cycles). Planned cumulative dose of cisplatin was 450 mg/m2 in both groups, while dose intensity was doubled in the Pw arm (50 mg/m2/week versus 25 mg/m2/week). The primary objective of the study was to compare the progression free survival (PFS) in the two arms. Secondary objectives were the overall response to chemotherapy and toxicity. RESULTS: between November 1988 and February 1992 285 patients were randomized in the two treatment arms. The two regimens resulted equally feasible. Planned dose intensity was achieved in both treatment groups (median 45 and 23 mg/m2/week). Toxicity was similar in the two groups, with the exception of grade 3-4 leukopenia which was more frequent in the experimental arm (9% vs 3%, p:0.02). Median follow up was 16.8 years. There were no differences between the two treatment arms in terms of PFS (17 months in the Pw arm, 18 in the Pst arm, p:0.57) and in terms of OS (35 months in the Pw arm, 32 in the Pst arm, p:0.97). CONCLUSION: dose-dense cisplatin is well tolerated, but does not seem to bring advantages, in terms of PFS and OS, compared to standard chemotherapy.
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Milette, Marie-Pierre. "Direct optimization of 3D dose distributions using collimator rotation." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/274.

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The primary goal of this thesis is to improve the precision and efficiency of radiation therapy treatment. This goal is achieved by developing and implementing a direct aperture optimization (DAO) platform where the multileaf collimator (MLC) is rotated between each aperture. The approach is referred to as rotating aperture optimization (RAO). A series of tests is performed to evaluate how a final optimized plan depends on MLC parameters. Imposing constraints on the leaf sequence results in increased efficiency and a simplification of the treatment plan without compromising the quality of the dose distribution. It is also shown that an arrangement of equispaced collimator angles takes full advantage of the flexibility associated with collimator rotation. A study including ten recurring nasopharynx cancer patients is used to evaluate the capabilities of RAO compared to other optimization techniques. It is shown that RAO plans require significantly less linac radiation output (monitor units or MU) while maintaining equivalent dose distribution quality compared to plans generated with the conventional fluence based approach. Furthermore with an improved collimator rotation speed, the RAO plans should be executable in the same or less time than plans generated with the fluence-based approach. For the second part of the study it is shown that plans generated with RAO are as good as or better than plans generated with standard fixed collimator DAO. Film and ion chamber measurements indicate that RAO plans can be delivered more accurately than DAO plans. Additional applications of DAO were investigated through collaboration with two PhD students. First, Monte Carlo was used to generate pencil beam dose distributions for DAO inverse treatment planning (MC-DAO). The MC-DAO technique correctly models traditionally difficult treatment geometries such as small fields and tissue inhomogeneities. The MC-DAO also takes advantage of the improved MU efficiency associated with the DAO technique. Secondly DAO is proposed for adaptive radiation therapy. The results show that plan re-adaptation can be performed more quickly than complete plan regeneration thereby minimizing the time the patient has to spend in the treatment room and reducing the potential for geometric errors in treatment delivery.
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Zhang, Pengfei, Neng Fan, Jie Shan, Steven E. Schild, Martin Bues, and Wei Liu. "Mixed integer programming with dose-volume constraints in intensity-modulated proton therapy." WILEY, 2017. http://hdl.handle.net/10150/626184.

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Background: In treatment planning for intensity-modulated proton therapy (IMPT), we aim to deliver the prescribed dose to the target yet minimize the dose to adjacent healthy tissue. Mixed-integer programming (MIP) has been applied in radiation therapy to generate treatment plans. However, MIP has not been used effectively for IMPT treatment planning with dose-volume constraints. In this study, we incorporated dose-volume constraints in an MIP model to generate treatment plans for IMPT. Methods: We created a new MIP model for IMPT with dose volume constraints. Two groups of IMPT treatment plans were generated for each of three patients by using MIP models for a total of six plans: one plan was derived with the Limited-memory Broyden-Fletcher-Goldfarb-Shanno (L-BFGS) method while the other plan was derived with our MIP model with dose-volume constraints. We then compared these two plans by dose-volume histogram (DVH) indices to evaluate the performance of the new MIP model with dose-volume constraints. In addition, we developed a model to more efficiently find the best balance between tumor coverage and normal tissue protection. Results: The MIP model with dose-volume constraints generates IMPT treatment plans with comparable target dose coverage, target dose homogeneity, and the maximum dose to organs at risk (OARs) compared to treatment plans from the conventional quadratic programming method without any tedious trial-and-error process. Some notable reduction in the mean doses of OARs is observed. Conclusions: The treatment plans from our MIP model with dose-volume constraints can meetall dose-volume constraints for OARs and targets without any tedious trial-and-error process. This model has the potential to automatically generate IMPT plans with consistent plan quality among different treatment planners and across institutions and better protection for important parallel OARs in an effective way.
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Ho, Kean Fatt. "Optimising dose escalated intensity modulated radiotherapy (IMRT) in head and neck cancer." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508596.

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Javedan, Khosrow. "Investigation of Buildup Dose for Therapeutic Intensity Modulated Photon Beams in Radiation Therapy." Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3449.

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Buildup dose of Mega Voltage (MV) photon beams can be a limiting factor in intensitymodulated radiation therapy (IMRT) treatments. Excessive doses can cause patient discomfort and treatment interruptions, while underdosing may lead to local failure. Many factors which contribute to buildup dose, including the photon beam energy spectrum, scattered or contaminant radiation and their angular distribution, are not modeled well in commercial treatment planning systems. The accurate Monte Carlo method was employed in the studies to estimate the doses. Buildup dose of 6MV photon beams was investigated for three fundamentally different IMRT modalities: between Helical TomoTherapy and traditional opposed tangential beams, solid IMRT and multileaf collimator (MLC)-based IMRT techniques. Solid IMRT, as an alternative to MLC, achieves prescription dose distribution objectives, according to our study. Measurements and Monte Carlo calculations of buildup dose in chest wall treatment were compared between TomoTherapy IMRT and traditional tangential-beam technique. The effect of bolus in helical delivery was also investigated in this study. In addition, measurements and Monte Carlo calculations of buildup dose in solid IMRT and MLC based IMRT treatment modalities were compared. A brass step compensator was designed and built for the solid IMRT. Matching MLC step sequences were used for the MLC IMRT. This dissertation also presents the commissioning of a Monte Carlo code system, BEAMnrc, for a Varian Trilogy linear accelerator (LINAC) and the application in buildup dose calculation. Scattered dose components, MLC component dose and mean spectral energy for the IMRT treatment techniques were analyzed. The agreement between measured 6MV and calculated depth dose and beam profiles was (± 1% or ±1 mm) for 10x10 and 40x40 cm2 fields. The optimum electron beam energy and its radial distribution incident on tungsten target were found to be 6 MeV and 1 mm respectively. The helical delivery study concluded that buildup dose is higher with TomoTherapy compared to the opposed tangential technique in chest wall treatment. The solid and MLC IMRT comparison concluded that buildup dose was up to 7% lower for solid IMRT compared to MLC IMRT due to beam hardening of brass.
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Gordon, Ian R. "Feasibility Study of Intensity Modulation for Low Dose Rate External Beam Radiation Therapy." University of Toledo Health Science Campus / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=mco1290109815.

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Zhang, Tianfang. "Direct optimization of dose-volume histogram metrics in intensity modulated radiation therapy treatment planning." Thesis, KTH, Skolan för teknikvetenskap (SCI), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-231548.

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In optimization of intensity-modulated radiation therapy treatment plans, dose-volumehistogram (DVH) functions are often used as objective functions to minimize the violationof dose-volume criteria. Neither DVH functions nor dose-volume criteria, however,are ideal for gradient-based optimization as the former are not continuously differentiableand the latter are discontinuous functions of dose, apart from both beingnonconvex. In particular, DVH functions often work poorly when used in constraintsdue to their being identically zero when feasible and having vanishing gradients on theboundary of feasibility.In this work, we present a general mathematical framework allowing for direct optimizationon all DVH-based metrics. By regarding voxel doses as sample realizations ofan auxiliary random variable and using kernel density estimation to obtain explicit formulas,one arrives at formulations of volume-at-dose and dose-at-volume which are infinitelydifferentiable functions of dose. This is extended to DVH functions and so calledvolume-based DVH functions, as well as to min/max-dose functions and mean-tail-dosefunctions. Explicit expressions for evaluation of function values and corresponding gradientsare presented. The proposed framework has the advantages of depending on onlyone smoothness parameter, of approximation errors to conventional counterparts beingnegligible for practical purposes, and of a general consistency between derived functions.Numerical tests, which were performed for illustrative purposes, show that smoothdose-at-volume works better than quadratic penalties when used in constraints and thatsmooth DVH functions in certain cases have significant advantage over conventionalsuch. The results of this work have been successfully applied to lexicographic optimizationin a fluence map optimization setting.
Vid optimering av behandlingsplaner i intensitetsmodulerad strålterapi används dosvolym- histogram-funktioner (DVH-funktioner) ofta som målfunktioner för att minimera avståndet till dos-volymkriterier. Varken DVH-funktioner eller dos-volymkriterier är emellertid idealiska för gradientbaserad optimering då de förstnämnda inte är kontinuerligt deriverbara och de sistnämnda är diskontinuerliga funktioner av dos, samtidigt som båda också är ickekonvexa. Speciellt fungerar DVH-funktioner ofta dåligt i bivillkor då de är identiskt noll i tillåtna områden och har försvinnande gradienter på randen till tillåtenhet. I detta arbete presenteras ett generellt matematiskt ramverk som möjliggör direkt optimering på samtliga DVH-baserade mått. Genom att betrakta voxeldoser som stickprovsutfall från en stokastisk hjälpvariabel och använda ickeparametrisk densitetsskattning för att få explicita formler, kan måtten volume-at-dose och dose-at-volume formuleras som oändligt deriverbara funktioner av dos. Detta utökas till DVH-funktioner och så kallade volymbaserade DVH-funktioner, såväl som till mindos- och maxdosfunktioner och medelsvansdos-funktioner. Explicita uttryck för evaluering av funktionsvärden och tillhörande gradienter presenteras. Det föreslagna ramverket har fördelarna av att bero på endast en mjukhetsparameter, av att approximationsfelen till konventionella motsvarigheter är försumbara i praktiska sammanhang, och av en allmän konsistens mellan härledda funktioner. Numeriska tester genomförda i illustrativt syfte visar att slät dose-at-volume fungerar bättre än kvadratiska straff i bivillkor och att släta DVH-funktioner i vissa fall har betydlig fördel över konventionella sådana. Resultaten av detta arbete har med framgång applicerats på lexikografisk optimering inom fluensoptimering.
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Sun, Jidi. "Implementation of 2-Step Intensity Modulated Arc Therapy." Thesis, University of Canterbury. Department of Physics and Astronomy, 2010. http://hdl.handle.net/10092/3844.

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Intensity modulated arc therapy is a novel treatment technique that has shown great potential to be superior to conventional intensity modulated radiotherapy, both in terms of treatment plan quality as well as treatment delivery. Based on previous literature, a simplified technique called two-step intensity modulated arc therapy (2-step IMAT) was implemented into a treatment planning system. In order to automatically generate treatment plans for this technique, a beam portal shaping method was developed to generate beam segments. A sensitivity analysis was carried out on a geometric phantom to determine optimal parameters for the 2-step IMAT implementation for that particular phantom. The segment weights were optimized using the dose-based and dose-volume-based objective functions. The optimal solution search was based on the gradient-descend algorithm. The dose-based objective function was implemented using a so-called lambda-value-dose-based objective function developed in this work in order to increase both speed and flexibility of the optimization. The successful implementation demonstrated the feasibility of automatic 2-step IMAT treatment planning. A comparison of conventional arc therapy and 2-step IMAT showed improvements in the target dose uniformity by about 50% for both geometric phantom and clinical paraspinal tumor case, whilst also improving the organ sparing. The comparisons between the lambda-value-dose-based and dose-volume-based optimizations showed a speed advantage of the former by a factor of over five in the phantom study. The current beam portal shaping approach can be improved by optimizing the segment width and including multiple organs-at-risk in the segment generation algorithm. Future work will also include the implementation of a stochastic optimization to minimize the chance of getting trapped in local minima during the segment weight optimization. In summary, the work of this research showed that the automatic 2-step IMAT planning is a viable technique that can result in highly conformal plans while keeping the treatment planning and delivery simple and straightforward.
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Obata, Yasunori, and Hiroshi Oguchi. "Commissioning of modulator-based IMRT with XiO treatment planning system." AIP Publishing, 2009. http://hdl.handle.net/2237/20613.

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Books on the topic "Dose intensity"

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Intensity-modulated radiation therapy. Bristol: Institute of Physics Pub., 2001.

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Braude, Jacob. Does the capital intensity of structural change matter for growth? Jerusalem: Bank of Israel, research department, 2004.

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Chisholm, Deanna A. The effects of background noise on visual search task performance: Does type of sound or intensity level make a difference. Sudbury, Ont: Laurentian University, Department of Psychology, 1994.

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Suminar, Bagus. Peranan komitmen organisasional dalam mempengaruhi partisipasi, ko-operasi, dan intensi keluar dosen wanita di Surabaya: Penelitian kajian wanita. [Surabaya]: STIE Perbanas Surabaya, 2004.

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Adomat, Renee. Does the length of time that a nurse works in an Intensive Therapy Unit (ITU), influence the type of touching communication she/he engages in with patients. Birmingham: University of Central England in Birmingham, 1993.

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United States. General Accounting Office. Accounting and Information Management Division, ed. Medicare: Methodology to identify and measure improper payments in the medicare program does not include all fraud. Washington, D.C. (P.O. Box 37050, Washington 20013): The Office, 2000.

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Seidman, A. D. Dose Intensity (Breast Disease, 14). Ios Pr Inc, 2001.

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Rowbottom, Carl. Treatment delivery, intensity-modulated radiotherapy, and image-guided radiotherapy. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199696567.003.0003.

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Chapter 3 discusses how successful delivery of external beam radiotherapy involves a number of complex processes beginning with the decision by the clinical oncologist to use radiotherapy as part of the patient’s cancer management, through the preparation and planning of the patient’s treatment, to the verification of the patient position and radiation dose delivered at the time of treatment.
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Pivokonský, Martin, Kateřina Novotná, Lenka Čermáková, and Radim Petříček, eds. Jar Tests for Water Treatment Optimisation. IWA Publishing, 2022. http://dx.doi.org/10.2166/9781789062694.

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Abstract The book is intended as a handbook providing detailed instructions for the correct conducting of jar tests, which are needed for the optimisation of the coagulation/flocculation process. It contains the essential theoretical background of coagulation/flocculation, including a description of the influence of different parameters on the coagulation efficiency of various impurities (e.g. pH value and type/dose of coagulant), and floc properties and their separation (e.g. mixing intensity, mixing time, but also type/concentration of coagulant and impurities). The principle of jar tests is explained and parameters possible to optimize (i.e. coagulation pH, coagulant dose, flocculation aid dose, mixing intensity and mixing time) are discussed. Laboratory equipment for jar tests is proposed, including mixers and instructions for calculating a mixing intensity (necessarily expressed by the global shear rate/velocity gradient G). Mixing intensities for various purposes are recommended. Detailed practical instructions of how to perform jar tests follow, including a determination of the dose of reagents for pH adjustment and coagulant dose, dosing sequence, floc separation after jar tests by sedimentation and/or centrifugation simulating sand filtration, sampling, measuring necessary parameters (pH, coagulant residuals, alkalinity, residual impurity concentrations etc.), data recording, data processing and jar test evaluation (with specific examples). The handbook also contains a supplementary part with tables for conversion of the molar to mass concentration (and vice versa) of coagulants, and instructions for diluting coagulants and reagents for pH adjustment. ISBN: 9781789062687 (paperback) ISBN: 9781789062694 (eBook) ISBN: 9781789062700 (ePUB)
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Pfiffner, Linda J., and Lauren M. Haack. Nonpharmacologic Treatments for Childhood Attention-Deficit/Hyperactivity Disorder and Their Combination with Medication. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0003.

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Of the nonpharmacological treatments for childhood attention-deficit/hyperactivity disorder (ADHD), behavioral interventions have the largest evidence base. Current behavioral interventions include behavioral parent training, behavioral classroom management, child skills training, behavioral multicomponent interventions, and multimodal treatment, which combines behavioral interventions and medication. This updated review of studies reveals significant behavioral treatment effects from randomized controlled trials on a wide range of child outcomes including ADHD and oppositional defiant disorder symptoms as well as areas of functional impairment such as homework, organizational, and social behaviors. Combined behavioral and medication treatments appear to reduce the needed dose or intensity of each intervention.
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Book chapters on the topic "Dose intensity"

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Brandt, Nicole. "Dose: Intensity, Response." In Encyclopedia of Behavioral Medicine, 701. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39903-0_1391.

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Upchurch Sweeney, C. Renn, J. Rick Turner, J. Rick Turner, Chad Barrett, Ana Victoria Soto, William Whang, Carolyn Korbel, et al. "Dose: Intensity, Response." In Encyclopedia of Behavioral Medicine, 630–31. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_1391.

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Sunta, C. M. "Intensity Growth with Dose." In Unraveling Thermoluminescence, 133–62. New Delhi: Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1940-8_6.

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Muggia, F. M., and I. Gill. "Optimizing Dose-Intensity: Combining Carboplatin with Cisplatin." In Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, 471–80. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-0738-7_45.

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Hryniuk, W. M. "Application of dose intensity to Neo-Adjuvant therapy." In Proceedings of the 3rd International Congress on Neo-Adjuvant Chemotherapy, 161–66. Paris: Springer Paris, 1991. http://dx.doi.org/10.1007/978-2-8178-0782-9_40.

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Levin, L. "Chemotherapy options in ovarian carcinoma — a dose intensity perspective." In Ovarian Cancer 3, 195–201. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4757-0136-4_20.

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Hryniuk, W. M. "Dose Intensity of Chemotherapy in High-Risk Breast Cancer." In High-Risk Breast Cancer, 221–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-74728-1_12.

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Chan, K., M. Schneider, R. Smee, S. Heng, and C. Baldock. "Monte Carlo Simulation Dose Calculation for Intensity Modulated Radiosurgery." In Radiosurgery, 84–94. Basel: KARGER, 2010. http://dx.doi.org/10.1159/000288721.

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Janka, G. E., O. Gobrecht, and S. Gross. "Dose Intensity and Prognosis in Acute Lymphocytic Leukemia of Childhood." In Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, 338–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78350-0_59.

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Lahanas, Michael, Eduard Schreibmann, Natasa Milickovic, and Dimos Baltas. "Intensity Modulated Beam Radiation Therapy Dose Optimization with Multiobjective Evolutionary Algorithms." In Lecture Notes in Computer Science, 648–61. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-36970-8_46.

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Conference papers on the topic "Dose intensity"

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Nathan, Steven, Lisa Lancaster, Carlo Albera, Marilyn Glassberg, Jeffrey Swigris, Frank Gilberg, Klaus-Uwe Kirchgaessler, Ute Petzinger, and Paul Noble. "Dose modifications and dose intensity during treatment with pirfenidone." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.oa1764.

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Youn, Hanbean, Ho Kyung Kim, Jinwoo Kim, Jonghee Yun, and Seungwoo Ha. "Intensity-modulated dental CBCT: noise and absorbed dose study." In Physics of Medical Imaging, edited by Guang-Hong Chen, Joseph Y. Lo, and Taly Gilat Schmidt. SPIE, 2018. http://dx.doi.org/10.1117/12.2293396.

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Faustino, C., N. Afonso, B. Sousa, J. Espírito Santo, and H. Rodrigues. "Relative dose intensity reduction in breast cancer adjuvant chemotherapy." In CTRC-AACR San Antonio Breast Cancer Symposium: 2008 Abstracts. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-4111.

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Weycker, D., J. Edelsberg, A. Kartashov, R. Barron, and G. Lyman. "P5-18-11: Incidence of Chemotherapy Dose Reductions and Dose Delays, and Reduced Chemotherapy Dose Intensity in Early Stage Breast Cancer." In Abstracts: Thirty-Fourth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 6‐10, 2011; San Antonio, TX. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/0008-5472.sabcs11-p5-18-11.

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Ono, Yasushi, Kazu Mishiba, Yuji Oyamada, Yoshiharu Hirata, and Katsuya Kondo. "Resolution improvement of point dose distribution in intensity modulated radiation therapy." In 2015 15th International Symposium on Communications and Information Technologies (ISCIT). IEEE, 2015. http://dx.doi.org/10.1109/iscit.2015.7458326.

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Kahlert, S., J. Rosenfeld, K. Mair, Y. Sorokina, J. Engel, and K. Friese. "Adjuvant chemotherapy for breast cancer – prognostic impact of relative dose-intensity." In CTRC-AACR San Antonio Breast Cancer Symposium: 2008 Abstracts. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-4109.

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Lomb, Lukas, Thomas R. Barends, and Ilme Schlichting. "Protein Crystal Structure Determination and Radiation Damage at a dose of 3 GGy using a Free-Electron Laser." In High Intensity Lasers and High Field Phenomena. Washington, D.C.: OSA, 2012. http://dx.doi.org/10.1364/hilas.2012.hm2c.1.

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Mosel, P., P. Sankar, E. Appi, J. F. Düsing, G. Dittmar, T. Püster, P. Jäschke, J. W. Vahlbruch, U. Morgner, and M. Kovacev. "X-ray dose and spectrum measurements with a novel X-ray detector for potential hazards of laser-matter interaction." In High Intensity Lasers and High Field Phenomena. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/hilas.2022.hth3b.2.

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Wu, Jia-Ming, Tsair-Fwu Lee, Ching-Jiang Chen, Chung-Ming Kuo, and Shyh-An Yeh. "Fractal Dimension Characteristic Analysis for Dose Verification in Intensity Modulation Radiation Therapy." In 2012 Sixth International Conference on Genetic and Evolutionary Computing (ICGEC). IEEE, 2012. http://dx.doi.org/10.1109/icgec.2012.95.

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Favret, AM, X. Li, N. Denduluri, PK Morrow, M. Bhor, RL Barron, R. Dhanda, et al. "Abstract P3-12-07: Dose delays, dose reductions, and relative dose intensity in early stage breast cancer patients receiving (neo)adjuvant chemotherapy in community oncology practices." In Abstracts: Thirty-Sixth Annual CTRC-AACR San Antonio Breast Cancer Symposium - Dec 10-14, 2013; San Antonio, TX. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/0008-5472.sabcs13-p3-12-07.

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Reports on the topic "Dose intensity"

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Griggs, Jennifer J. Adequacy of Chemotherapy Dose Intensity Among African-American Women with Her-2/neu-Positive Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2004. http://dx.doi.org/10.21236/ada429764.

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Griggs, Jennifer J. Adequacy of Chemotherapy Dose Intensity Among African-American Women with HER-2/neu-Positive Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada410338.

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Griggs, Jennifer J. Adequacy of Chemotherapy Dose Intensity Among African-American Women with HER-2/neu-Positive Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2003. http://dx.doi.org/10.21236/ada421764.

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Mason, Vera C., Gary W. Shults, Joseph S. Cohen, and Vicki Loveridge. Effect of Irradiation Dose, Temperature and Fat Level on the Color Intensity and Textural Characteristics of Beef Rolls. Fort Belvoir, VA: Defense Technical Information Center, August 1999. http://dx.doi.org/10.21236/ada368065.

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Koziel, Jacek, Yael Laor, Jeffrey Zimmerman, Robert Armon, Steven Hoff, and Uzi Ravid. Simultaneous Treatment of Odorants and Pathogens Emitted from Confined Animal Feeding Operations (CAFOs) by Advanced Oxidation Technologies. United States Department of Agriculture, January 2009. http://dx.doi.org/10.32747/2009.7592646.bard.

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A feasibility study was conducted, aiming to explore the potential effectiveness of UV/TiO2/O3 photooxidation technologies for simultaneous treatment of odorant and pathogen emissions from livestock and poultry operations. Several key parameters were tested in laboratory (US) and semi-pilot (Israel) scale conditions including: the effects of light energy dose (treatment time and light intensity), relative humidity and air temperature, UV wavelength, presence of photocatalyst (TiO2) and the presence of ozone. Removal and conversion of odor, target gases (sulfur-containing volatile organic compounds S-VOCs, volatile fatty acids (VFAs), phenolics, and ammonia), and airborne pathogens was tested. Up to 100% removal (below method detection level) of S-VOCs, VFAs, and phenolics, the overall odor, and up to 64.5% of ammonia was achieved with optimized treatment. Treatments involving deep UV band (185 nm) and photocatalyst (TiO2) were more efficient in removal/conversion of odorous gases and odor. The estimate of the operational cost of treatment was based on measured emissions of several odorous VOCs from full scale, commercial swine farm ranges from $0.15 to $0.59 per finisher pig. This figure represents significantly lower cost compared with the cost of biofiltration or air scrubbing.
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Cortes, Kalena, Joshua Goodman, and Takako Nomi. Intensive Math Instruction and Educational Attainment: Long-Run Impacts of Double-Dose Algebra. Cambridge, MA: National Bureau of Economic Research, June 2014. http://dx.doi.org/10.3386/w20211.

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Whatmore, Douglas N. Effect of Empiric Low-Dose Amphotericin B on the Development of Disseminated Candidiasis in Surgical Intensive Care Unit. Fort Belvoir, VA: Defense Technical Information Center, January 1995. http://dx.doi.org/10.21236/ada293748.

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Runals, Stephen E. Command and Control: Does Current U.S. Army Tactical Command and Control Doctrine Meet the Requirement for Today's High Intensity Battlefield? Fort Belvoir, VA: Defense Technical Information Center, December 1985. http://dx.doi.org/10.21236/ada167258.

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Tavares, Sheilla Siedler, Mavilde da Luz Gonçalves Pedreira, and Denise Miyuki Kusahara. Aplicativo Transped Care para continuidade da assistência de enfermagem na transição do cuidado intensivo pediátricos. Universidade Federal de São Paulo, 2023. http://dx.doi.org/10.34024/agits20220008.

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A transição do cuidado, no contexto em que foi desenvolvido para o Transped Care App, contempla a mudança do estado do cuidado crítico da criança e família para o cuidado intermediário. No momento que antecede, durante e após a transição pode haver eventos adversos que comprometem a continuidade da recuperação do paciente pediátrico. Os principais eventos adversos neste momento crucial estão relacionados à comunicação entre profissionais, pacientes e famílias. O uso da ferramenta poderá contribuir para a comunicação efetiva, continuação dos cuidados de enfermagem, redução dos erros e melhorar a segurança do paciente no período da transição.
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Shumway, Dean A., Kimberly S. Corbin, Magdoleen H. Farah, Kelly E. Viola, Tarek Nayfeh, Samer Saadi, Vishal Shah, et al. Partial Breast Irradiation for Breast Cancer. Agency for Healthcare Research and Quality (AHRQ), January 2023. http://dx.doi.org/10.23970/ahrqepccer259.

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Objectives. To evaluate the comparative effectiveness and harms of partial breast irradiation (PBI) compared with whole breast irradiation (WBI) for early-stage breast cancer, and how differences in effectiveness and harms may be influenced by patient, tumor, and treatment factors, including treatment modality, target volume, dose, and fractionation. We also evaluated the relative financial toxicity of PBI versus WBI. Data sources. MEDLINE®, Embase®, Cochrane Central Registrar of Controlled Trials, Cochrane Database of Systematic Reviews, Scopus, and various grey literature sources from database inception to June 30, 2022. Review methods. We included randomized clinical trials (RCTs) and observational studies that enrolled adult women with early-stage breast cancer who received one of six PBI modalities: multi-catheter interstitial brachytherapy, single-entry catheter brachytherapy (also known as intracavitary brachytherapy), 3-dimensional conformal external beam radiation therapy (3DCRT), intensity-modulated radiation therapy (IMRT), proton radiation therapy, intraoperative radiotherapy (IORT). Pairs of independent reviewers screened and appraised studies. Results. Twenty-three original studies with 17,510 patients evaluated the comparative effectiveness of PBI, including 14 RCTs, 6 comparative observational studies, and 3 single-arm observational studies. PBI was not significantly different from WBI in terms of ipsilateral breast recurrence (IBR), overall survival, or cancer-free survival at 5 and 10 years (high strength of evidence [SOE]). Evidence for cosmetic outcomes was insufficient. Results were generally consistent when PBI modalities were compared with WBI, whether compared individually or combined. These PBI approaches included 3DCRT, IMRT, and multi-catheter interstitial brachytherapy. Compared with WBI, 3DCRT showed no difference in IBR, overall survival, or cancer-free survival at 5 and 10 years (moderate to high SOE); IMRT showed no difference in IBR or overall survival at 5 and 10 years (low SOE); multi-catheter interstitial brachytherapy showed no difference in IBR, overall survival, or cancer-free survival at 5 years (low SOE). Compared with WBI, IORT was associated with a higher IBR rate at 5, 10, and over 10 years (high SOE), with no difference in overall survival, cancer-free survival, or mastectomy-free survival (low to high SOE). There were significantly fewer acute adverse events (AEs) with PBI compared with WBI, with no apparent difference in late AEs (moderate SOE). Data about quality of life were limited. Head-to-head comparisons between the different PBI modalities showed insufficient evidence to estimate an effect on main outcomes. There were no significant differences in IBR or other outcomes according to patient, tumor, and treatment characteristics; however, data for subgroups were insufficient to draw conclusions. Eight studies addressed concepts closely related to financial toxicity. Compared with conventionally fractionated WBI, accelerated PBI was associated with lower transportation costs and days away from work. PBI was also associated with less subjective financial difficulty at various time points after radiotherapy. Conclusions. Clinical trials that compared PBI with WBI demonstrate no significant difference in the risk of IBR. PBI is associated with fewer acute AEs and may be associated with less financial toxicity. The current evidence supports the use of PBI in appropriately selected patients with early-stage breast cancer. Further investigation is needed to evaluate the outcomes of PBI in patients with various clinical and tumor characteristics, and to define optimal radiation treatment dose and technique for PBI.
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