Academic literature on the topic 'DNMT2'
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Journal articles on the topic "DNMT2"
MUND, Cora, Tanja MUSCH, Martin STRÖDICKE, Birte ASSMANN, En LI, and Frank LYKO. "Comparative analysis of DNA methylation patterns in transgenic Drosophila overexpressing mouse DNA methyltransferases." Biochemical Journal 378, no. 3 (March 15, 2004): 763–68. http://dx.doi.org/10.1042/bj20031567.
Full textLiu, Kui, Yun Fei Wang, Carmen Cantemir, and Mark T. Muller. "Endogenous Assays of DNA Methyltransferases: Evidence for Differential Activities of DNMT1, DNMT2, and DNMT3 in Mammalian Cells In Vivo." Molecular and Cellular Biology 23, no. 8 (April 15, 2003): 2709–19. http://dx.doi.org/10.1128/mcb.23.8.2709-2719.2003.
Full textDel Castillo Falconi, Victor M., Karla Torres-Arciga, Genaro Matus-Ortega, José Díaz-Chávez, and Luis A. Herrera. "DNA Methyltransferases: From Evolution to Clinical Applications." International Journal of Molecular Sciences 23, no. 16 (August 12, 2022): 8994. http://dx.doi.org/10.3390/ijms23168994.
Full textKIM, SEON-HEE, HYE-JEONG CHO, WOON-MOK SOHN, CHUN-SEOB AHN, YOON KONG, HYUN-JONG YANG, and YOUNG-AN BAE. "Egg-specific expression of protein with DNA methyltransferase activity in the biocarcinogenic liver fluke Clonorchis sinensis." Parasitology 142, no. 9 (June 3, 2015): 1228–38. http://dx.doi.org/10.1017/s0031182015000566.
Full textZhu, Huolan, Xiang Wang, Xuyang Meng, Yiya Kong, Yi Li, Chenguang Yang, Ying Guo, et al. "Selenium Supplementation Improved Cardiac Functions by Suppressing DNMT2-Mediated GPX1 Promoter DNA Methylation in AGE-Induced Heart Failure." Oxidative Medicine and Cellular Longevity 2022 (April 6, 2022): 1–12. http://dx.doi.org/10.1155/2022/5402997.
Full textVivekanandan, Perumal, Hubert Darius-J. Daniel, Rajesh Kannangai, Francisco Martinez-Murillo, and Michael Torbenson. "Hepatitis B Virus Replication Induces Methylation of both Host and Viral DNA." Journal of Virology 84, no. 9 (February 10, 2010): 4321–29. http://dx.doi.org/10.1128/jvi.02280-09.
Full textHuang, Zhi-Xuan, Jing Li, Qing-Ping Xiong, Hao Li, En-Duo Wang, and Ru-Juan Liu. "Position 34 of tRNA is a discriminative element for m5C38 modification by human DNMT2." Nucleic Acids Research 49, no. 22 (December 6, 2021): 13045–61. http://dx.doi.org/10.1093/nar/gkab1148.
Full textLyko, Frank. "RNA Methylation and Its Role in the Hematopoietic System." Blood 130, Suppl_1 (December 7, 2017): SCI—52—SCI—52. http://dx.doi.org/10.1182/blood.v130.suppl_1.sci-52.sci-52.
Full textGoll, Mary Grace, Finn Kirpekar, Keith A. Maggert, Jeffrey A. Yoder, Chih-Lin Hsieh, Xiaoyu Zhang, Kent G. Golic, Steven E. Jacobsen, and Timothy H. Bestor. "Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2." Science 311, no. 5759 (January 20, 2006): 395–98. http://dx.doi.org/10.1126/science.1120976.
Full textBhattacharya, Tamanash, Danny W. Rice, John M. Crawford, Richard W. Hardy, and Irene L. G. Newton. "Evidence of Adaptive Evolution in Wolbachia-Regulated Gene DNMT2 and Its Role in the Dipteran Immune Response and Pathogen Blocking." Viruses 13, no. 8 (July 27, 2021): 1464. http://dx.doi.org/10.3390/v13081464.
Full textDissertations / Theses on the topic "DNMT2"
Müller, Sara [Verfasser]. "Biologische Funktionsanalyse und Identifizierung neuer Substrate der Methyltransferase Dnmt2 / Sara Müller." Kassel : Universitätsbibliothek Kassel, 2012. http://d-nb.info/101926845X/34.
Full textKiani, Jafar. "Hérédité épigénétique et méthylation des ARNs : rôle de la méthyltransférase Dnmt2." Nice, 2011. http://www.theses.fr/2011NICE4093.
Full textSchuster, Isabelle [Verfasser]. "Strukturelle und funktionelle Charakterisierung des Dnmt2-Homologs DnmA von Dictyostelium discoideum / Isabelle Schuster." Kassel : Universitätsbibliothek Kassel, 2016. http://d-nb.info/1101616091/34.
Full textHartmann, Mark [Verfasser], and Frank [Akademischer Betreuer] Lyko. "Centromeric tRNA and Dnmt2-mediated Methylation in Mitotic Chromosome Segregation / Mark Hartmann ; Betreuer: Frank Lyko." Heidelberg : Universitätsbibliothek Heidelberg, 2018. http://d-nb.info/1177148862/34.
Full textDurdevic, Zeljko [Verfasser], and Frank [Akademischer Betreuer] Lyko. "Characterization of the Biological Function of Dnmt2 in Drosophila melanogaster / Zeljko Durdevic ; Betreuer: Frank Lyko." Heidelberg : Universitätsbibliothek Heidelberg, 2013. http://d-nb.info/1177249774/34.
Full textKaiser, Steffen [Verfasser]. "Investigations on DNA methylation by Dnmt2 and impact of tRNA modifications on TLR7 stimulation / Steffen Kaiser." Mainz : Universitätsbibliothek Mainz, 2015. http://d-nb.info/1080401431/34.
Full textShanmugam, Raghuvaran [Verfasser], and Albert [Akademischer Betreuer] Jeltsch. "Biochemical characterisation of tRNA-Asp methyltransferase Dnmt2 and its physiological significance / Raghuvaran Shanmugam. Betreuer: Albert Jeltsch." Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2014. http://d-nb.info/1049931661/34.
Full textVieira, Gilberto Cavalheiro. "Modelagem molecular e imunodetecção de DNA Metiltransferases 2 de Drosofilídeos : uma abordagem evolutiva da enigmática DNMT2." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/117889.
Full textThe methylation of genomic DNA is a major mechanism of epigenetic regulation in organisms. Among the different classes of DNA MTase the M5C-MTase are as widely distributed in prokaryotes to eukaryotes. In vertebrates there are three different families: DNMT1, DNMT2 and DNMT3a and 3b. The DNMT1 has activity with the hemimethylated DNA. The DNMT3a and 3b are responsible for de novo methylation. While the DNMT2 subfamily has its catalytic sites highly conserved from prokaryotes to eukaryotes, having properties that allow performing functions of both de novo and maintenance methylation. Furthermore, the DNMT2 family can act methylating cytokines, tRNAs or DNA. In mammals, invertebrates and plants, DNMT2 is classified primarily in vivo as a tRNA MTase. However,DNA-MTase activity by these enzymes has been described, even at low levels. The question is the preferred activities of DNMT2 and mechanisms that modulate its activity, because in organisms that do not have the canonical DNA-MTases (DNMT1 and DNMT3), but have cytokines methylated in its genome, the DNMT2 acts as MTase on both substrates. Drosophila species are known as Dnmt2-only. The importance of DNMT2’s role in ecological and evolutionary context in this species group is reflected by presence of a peculiar phenomenon: the sex-specific methylation described by our research group, presents in willistoni subgroup of Drosophila. In this study, DNMT2 of D. melanogaster, D. willistoni and Mus musculus were modeled by different methodologies. comparative analyzes with the crystallographic DNMT2 structures deposited in the PDB database were performed from these models, in order to establish the evolutionary and functional relationships between the different enzymes. Additionally, evolutionary and structural characterization studies of the 22 species, with the validated DNMT2 models of two species belonging to different evolutionary drosophilids groups, were conducted that have had their genomes sequenced and deposited in FlyBase data pack, adding the DNMT2 sequence of Drosophila tropicalis (willistoni subgroup) sequenced by our research group. The results of evolutionary and structural analyzes suggest differences between the DNMT2 properties of subgroup willistoni species from the other drosophilids. These results indicate that even species that have close evolutionary relationships may have adaptive mechanisms that establish gradations of DNMT2 affinity for different substrates, without the need of drastic changes in enzyme architecture.
Liebers, Reinhard Kai [Verfasser], and Frank [Akademischer Betreuer] Lyko. "Dnmt2 in RNA methylation, RNA inheritance, and environmental responses in the mouse / Reinhard Kai Liebers ; Betreuer: Frank Lyko." Heidelberg : Universitätsbibliothek Heidelberg, 2016. http://d-nb.info/1180614186/34.
Full textLiebers, Reinhard [Verfasser], and Frank [Akademischer Betreuer] Lyko. "Dnmt2 in RNA methylation, RNA inheritance, and environmental responses in the mouse / Reinhard Kai Liebers ; Betreuer: Frank Lyko." Heidelberg : Universitätsbibliothek Heidelberg, 2016. http://d-nb.info/1180614186/34.
Full textBook chapters on the topic "DNMT2"
Arnemann, J. "DNA-Methyltransferase (DNMT)." In Springer Reference Medizin, 718. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_3463.
Full textArnemann, J. "DNA-Methyltransferase (DNMT)." In Lexikon der Medizinischen Laboratoriumsdiagnostik, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_3463-1.
Full textYildiz, Can Bora, and Geraldine Zimmer-Bensch. "Role of DNMTs in the Brain." In Advances in Experimental Medicine and Biology, 363–94. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-11454-0_15.
Full textTajima, Shoji, Isao Suetake, Kohei Takeshita, Atsushi Nakagawa, and Hironobu Kimura. "Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases." In Advances in Experimental Medicine and Biology, 63–86. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-43624-1_4.
Full textTajima, Shoji, Isao Suetake, Kohei Takeshita, Atsushi Nakagawa, Hironobu Kimura, and Jikui Song. "Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases." In Advances in Experimental Medicine and Biology, 45–68. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-11454-0_3.
Full textAmruth Maroju, Pranay, and Kommu Naga Mohan. "DNA Methyltransferases and Schizophrenia: Current Status." In Psychosis - Phenomenology, Psychopathology and Pathophysiology [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98567.
Full textSvedružić, Željko M. "Dnmt1." In Progress in Molecular Biology and Translational Science, 221–54. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-387685-0.00006-8.
Full text"DNMTs." In Encyclopedia of Cancer, 1147. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_1698.
Full text"Methyltransferase, DNA (dnmt1, dnmt1-b, 19p13.3-p13.2)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics, 1201. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_10292.
Full textSharif, Jafar, and Haruhiko Koseki. "Recruitment of Dnmt1." In Progress in Molecular Biology and Translational Science, 289–310. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-387685-0.00008-1.
Full textConference papers on the topic "DNMT2"
Laranjeira, Angelo B., Erich Huang, Larry Rubinstein, Dat Nguyen, and Sherry X. Yang. "Abstract 3847: Knockout of DNMT1 using CRISPR gene-editing technology confers resistance to DNMT inhibitors in human breast cancer cells." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-3847.
Full textLaranjeira, Angelo B., Erich Huang, Larry Rubinstein, Dat Nguyen, and Sherry X. Yang. "Abstract 3847: Knockout of DNMT1 using CRISPR gene-editing technology confers resistance to DNMT inhibitors in human breast cancer cells." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-3847.
Full textCai, Yi, Hsing-chen Tsai, Ray-whay Yen, Limin Xia, Yang Zhang, and Stephen Baylin. "Abstract LB-150: Genetic depletion of DNMT1 reveals a DNMT1 threshold controlling DNA methylation in human cells." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-lb-150.
Full textLaranjeira, Angelo B., Dat Nguyen, Erich Huang, James H. Doroshow, and Sherry X. Yang. "Abstract 5081: Disruption of DNA methyltransferase (DNMT) 1 confers resistance to DNMT inhibitors in human colorectal cancer cells." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5081.
Full textFerreira, Nancy, Darley Ferreira, and Thais Ferreira. "GENETIC EVALUATION OF MICROCALCIFICATIONS AS A PROGNOSTIC FACTOR." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2101.
Full textSILVA, CAMILA T. DA, Fernanda Molognoni, Fabiana H. M. de Melo, and Miriam Galvonas Jasiulionis. "Abstract 426: Transcriptional regulation of dnmt1 by E2F1 in melanoma progression." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-426.
Full textLee, Gun Eui, and Keith D. Robertson. "Abstract 1054: The role of DNMT1 in the DNA damage response." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1054.
Full textMartínez Fernández, Liliam, and Jose Luis Medina Franco. "Identification of novel DNA Methyltransferase 1 (DNMT1) inhibitors from focused databases." In 7th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/ecmc2021-11570.
Full textTohme, Rita, Francis Enane, Caroline Schuerger, Xiaorong Gu, Melissa Fishel, John Pink, Daniel Lindner, Davendra Sohal, and Yogen Saunthararajah. "Abstract 1088: Advancing non-cytotoxic DNMT1-targeting to treat chemorefractory pancreatic cancer." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1088.
Full textEndo, Kanenori, Takanori Miyake, Soichiro Honjo, Shunichi Tsujitani, Yasuaki Hirooka, and Masahide Ikeguchi. "Abstract 185: Protein expression of DNMT1, DNMT3a, and DNMT3b in human hepatocellular carcinoma." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-185.
Full textReports on the topic "DNMT2"
Sarkisova, Karine, A. Gabova, E. Fedosova, A. Shatskova, M. Rudenok, V. Stanishevskaya, M. Shadrina, and P. Slominsky. Maternal methyl-enriched diet reduces absence seizures and depression-like comorbidity, and increases DNMT1 and HCN1 gene expression in the somatosensory cortex in adult offspring. LLC MAKS Press, June 2020. http://dx.doi.org/10.29003/m1395.fens-2020.
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