Academic literature on the topic 'DNA unzipping'
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Journal articles on the topic "DNA unzipping"
Krautbauer, Rupert, Matthias Rief, and Hermann E. Gaub. "Unzipping DNA Oligomers." Nano Letters 3, no. 4 (April 2003): 493–96. http://dx.doi.org/10.1021/nl034049p.
Full textChakrabarti, Buddhapriya, and David R. Nelson. "Shear Unzipping of DNA†." Journal of Physical Chemistry B 113, no. 12 (March 26, 2009): 3831–36. http://dx.doi.org/10.1021/jp808232p.
Full textKafri, Y., D. Mukamel, and L. Peliti. "Melting and unzipping of DNA." European Physical Journal B - Condensed Matter 27, no. 1 (May 1, 2002): 135–46. http://dx.doi.org/10.1140/epjb/e20020138.
Full textAmnuanpol, Sitichoke. "Physical origin of DNA unzipping." Journal of Biological Physics 42, no. 1 (August 26, 2015): 69–82. http://dx.doi.org/10.1007/s10867-015-9393-0.
Full textCALVO, J., J. NIETO, J. SOLER, and M. O. VÁSQUEZ. "ON A DISPERSIVE MODEL FOR THE UNZIPPING OF DOUBLE-STRANDED DNA MOLECULES." Mathematical Models and Methods in Applied Sciences 24, no. 03 (December 29, 2013): 495–511. http://dx.doi.org/10.1142/s0218202513500577.
Full textLubensky, David K., and David R. Nelson. "Pulling Pinned Polymers and Unzipping DNA." Physical Review Letters 85, no. 7 (August 14, 2000): 1572–75. http://dx.doi.org/10.1103/physrevlett.85.1572.
Full textVolkov, S. N., and A. V. Solov’yov. "The mechanism of DNA mechanical unzipping." European Physical Journal D 54, no. 3 (June 30, 2009): 657–66. http://dx.doi.org/10.1140/epjd/e2009-00194-5.
Full textMathé, Jérôme, Hasina Visram, Virgile Viasnoff, Yitzhak Rabin, and Amit Meller. "Nanopore Unzipping of Individual DNA Hairpin Molecules." Biophysical Journal 87, no. 5 (November 2004): 3205–12. http://dx.doi.org/10.1529/biophysj.104.047274.
Full textViasnoff, V., N. Chiaruttini, J. Muzard, and U. Bockelmann. "Force fluctuations assist nanopore unzipping of DNA." Journal of Physics: Condensed Matter 22, no. 45 (October 29, 2010): 454122. http://dx.doi.org/10.1088/0953-8984/22/45/454122.
Full textLi, Xinqiong, Guiqin Song, Linqin Dou, Shixin Yan, Ming Zhang, Weidan Yuan, Shirong Lai, et al. "The structure and unzipping behavior of dumbbell and hairpin DNA revealed by real-time nanopore sensing." Nanoscale 13, no. 27 (2021): 11827–35. http://dx.doi.org/10.1039/d0nr08729g.
Full textDissertations / Theses on the topic "DNA unzipping"
Baldazzi, Valentina. "Statistical mechanics of unzipping : Bayesian inference of DNA sequence." Université Louis Pasteur (Strasbourg) (1971-2008), 2006. https://publication-theses.unistra.fr/public/theses_doctorat/2005/BALDAZZI_Valentina_2005.pdf.
Full textHerskowitz, Lawrence J. "Kinetic and statistical mechanical modeling of DNA unzipping and kinesin mechanochemistry." THE UNIVERSITY OF NEW MEXICO, 2011. http://pqdtopen.proquest.com/#viewpdf?dispub=3440145.
Full textMarenduzzo, Davide. "Phases of Polymers and Biopolymers." Doctoral thesis, SISSA, 2002. http://hdl.handle.net/20.500.11767/4581.
Full textOkyay, Çağla. "Experimental study and molecular dynamics (MD) modeling of a nucleic acid in nano-confinement." Electronic Thesis or Diss., université Paris-Saclay, 2024. https://www.biblio.univ-evry.fr/theses/2024/2024UPASF063.pdf.
Full textNanopore technology has emerged as a powerful tool for studying biomolecular transport, particularly for the translocation and unzipping of DNA molecules. Experimental studies have shown the ability of α-hemolysin (αHL) nanopores to distinguish between different DNA sequences and ori-entations. However, experimental results primarily provide blocked current and translocation time information, leaving molecular-level details of the unzipping process unexplored. All-atom molecular dynamics (MD) simulations, though informative, are limited by short time scales. Coarse-grained (CG) MD simulations using the MARTINI force field, on the other hand, enable the study of DNA transport over extended time scales, approaching those observed experimentally.This thesis investigates the dynamics of both ssDNA translocation and dsDNA unzipping through the αHL nanopore using a combination of experimental techniques and CG-steered MD (SMD) simulations. Experimental studies explored the translocation times of ssDNA at the 3' and 5' ends, as well as the unzipping times of dsDNA under various conditions, including different duplex structures and applied voltages. Our findings on ssDNA translocation aligned with previous experimental and theoretical results, confirming faster translocation of 3' oriented ssDNA. Additionally, distinct unzipping times were observed for the different duplex structures under identical experimental conditions, with an exponential relationship noted between unzipping time and applied voltage. As the duplex length increased, the unzipping mechanisms appeared to vary depending on the duplex structure. However, the underlying molecular mechanisms behind these translocation and unzipping behaviors remain experimentally inaccessible, highlighting the need for further theoretical studies.By employing CG MD simulations, the influence of ssDNA orientation, sequence composition, and pulling force on translocation dynamics were computationally examined. Our simulation results reproduced the key experimental findings, such as the wide distribution of the translocation times, the orientation-dependent translocation behaviors, the crucial role of electrostatic interactions be-tween DNA and the nanopore, highlighting the impact of DNA phosphate charges on translocation rates, and the sequence-dependent translocation dynamics under varying applied forces. Specifically, the ratio of translocation times of purine and pyrimidine bases was also found to be in good agreement with the experimental findings. As a result of the CG simulations, a non-linear relation-ship between translocation velocity and the applied force was observed. Additionally, differences in DNA conformations inside the nanopore provided additional explanation for the sequence- and orientation-dependent translocation behaviors.This study validates the MARTINI CG model as an effective tool for investigating DNA transport, demonstrating its ability to complement experimental data. Our findings suggest that CG MD simulations are well suited for uncovering the molecular mechanisms underlying DNA unzipping, offering insights that are otherwise inaccessible through current experimental techniques
Books on the topic "DNA unzipping"
Hatch, Kristi Renee. Probing the mechanical stability of DNA by unzipping and rezipping the DNA at constant force. 2008.
Find full textRegenerative Processes Involving the CAMP Unzipping of DNA: Synthesis of Proteins Integrating Plasticity and Longevity. Nova Science Publishers, Incorporated, 2017.
Find full textBensimon, David, Vincent Croquette, Jean-François Allemand, Xavier Michalet, and Terence Strick. Single-Molecule Studies of Nucleic Acids and Their Proteins. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198530923.001.0001.
Full textBook chapters on the topic "DNA unzipping"
Merstorf, Céline, Benjamin Cressiot, Manuela Pastoriza-Gallego, Abdel Ghani Oukhaled, Laurent Bacri, Jacques Gierak, Juan Pelta, Loïc Auvray, and Jérôme Mathé. "DNA Unzipping and Protein Unfolding Using Nanopores." In Methods in Molecular Biology, 55–75. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-773-6_4.
Full textCissé, Ismaïl, Pierre Mangeol, and Ulrich Bockelmann. "DNA Unzipping and Force Measurements with a Dual Optical Trap." In Single Molecule Analysis, 45–61. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-282-3_3.
Full textdelToro, Damian J., and Douglas E. Smith. "Measuring Unzipping and Rezipping of Single Long DNA Molecules with Optical Tweezers." In Methods in Molecular Biology, 371–92. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8556-2_19.
Full textBensimon, David, Vincent Croquette, Jean-François Allemand, Xavier Michalet, and Terence Strick. "Structural Transitions in DNA." In Single-Molecule Studies of Nucleic Acids and Their Proteins, 105–18. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198530923.003.0005.
Full textLi, Ming, and Michelle D. Wang. "Unzipping Single DNA Molecules to Study Nucleosome Structure and Dynamics." In Methods in Enzymology, 29–58. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-391938-0.00002-1.
Full textConference papers on the topic "DNA unzipping"
Lubensky, David K. "Unzipping DNA: From Pulling to Pores and Back Again." In UNSOLVED PROBLEMS OF NOISE AND FLUCTUATIONS: UPoN 2002: Third International Conference on Unsolved Problems of Noise and Fluctuations in Physics, Biology, and High Technology. AIP, 2003. http://dx.doi.org/10.1063/1.1584908.
Full textYe, Fan, James T. Inman, and Michelle D. Wang. "Mechanical unzipping of DNA molecules in parallel using nanophotonic tweezers." In Optical Trapping and Optical Micromanipulation XVII, edited by Kishan Dholakia and Gabriel C. Spalding. SPIE, 2020. http://dx.doi.org/10.1117/12.2570629.
Full textNeuman, Keir C., and Yeonee Seol. "Untwisting and Unzipping: Magnetic Tweezers Based Measurements of DNA Processing Enzymes." In Optical Trapping Applications. Washington, D.C.: OSA, 2015. http://dx.doi.org/10.1364/ota.2015.otw3e.1.
Full textSingh, Amar, and Navin Singh. "Role of chain stiffness and end entropy in the unzipping of DNA chain." In PROCEEDING OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN APPLIED PHYSICS AND MATERIAL SCIENCE: RAM 2013. AIP, 2013. http://dx.doi.org/10.1063/1.4810670.
Full textWang, Michelle D., Steven J. Koch, Alla Shundrovsky, and Benjamin C. Jantzen. "Unzipping force analysis of protein association (UFAPA): a novel technique to probe protein-DNA interactions." In SPIE's First International Symposium on Fluctuations and Noise, edited by Sergey M. Bezrukov, Hans Frauenfelder, and Frank Moss. SPIE, 2003. http://dx.doi.org/10.1117/12.500332.
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