Relevant bibliographies by topics / DNA repair

Academic literature on the topic 'DNA repair'

Author: Grafiati
Published: 4 June 2021
Last updated: 29 July 2024

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Journal articles on the topic "DNA repair"

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Sánchez-Pérez, Isabel, and Rosario Perona Abellón. "DNA repair." Revista de Oncología 3, no. 4 (July 2001): 224–27. http://dx.doi.org/10.1007/bf02712696.

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Myles, Gary M., and Aziz Sancar. "DNA repair." Chemical Research in Toxicology 2, no. 4 (July 1989): 197–226. http://dx.doi.org/10.1021/tx00010a001.

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Jacquet, Karine, and Jacques Côté. "DNA repair." Cell Cycle 13, no. 7 (February 28, 2014): 1059. http://dx.doi.org/10.4161/cc.28383.

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Fleck, O. "DNA repair." Journal of Cell Science 117, no. 4 (February 15, 2004): 515–17. http://dx.doi.org/10.1242/jcs.00952.

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Zhang, Yanbin, and Feng Gong. "DNA repair." Methods 48, no. 1 (May 2009): 1–2. http://dx.doi.org/10.1016/j.ymeth.2009.05.001.

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Barnes, Deborah E., Tomas Lindahl, and Barbara Sedgwick. "DNA repair." Current Opinion in Cell Biology 5, no. 3 (June 1993): 424–33. http://dx.doi.org/10.1016/0955-0674(93)90007-d.

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Ujhazy, Peter, and David Stewart. "DNA Repair." Journal of Thoracic Oncology 4, no. 11 (November 2009): S1068—S1070. http://dx.doi.org/10.1097/01.jto.0000361754.25037.2c.

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Carell, Thomas. "DNA Repair." Angewandte Chemie International Edition 54, no. 51 (November 19, 2015): 15330–33. http://dx.doi.org/10.1002/anie.201509770.

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Howard-Flanders, Paul. "DNA repair." Trends in Biochemical Sciences 10, no. 9 (September 1985): 370. http://dx.doi.org/10.1016/0968-0004(85)90122-7.

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Van De Putte, P. "The DNA repair manual DNA repair and mutagenesis." Trends in Biochemical Sciences 20, no. 10 (October 1995): 440. http://dx.doi.org/10.1016/s0968-0004(00)89096-9.

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Dissertations / Theses on the topic "DNA repair"

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Moorwood, Kim. "DNA mismatch repair." Thesis, University of Sussex, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580146.

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White, C. I. "DNA repair in yeast." Thesis, Open University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333151.

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Boal, Amie Kathleen Parker Carl Stevens Barton Jacqueline K. "DNA-mediated charge transport in DNA repair /." Diss., Pasadena, Calif. : California Institute of Technology, 2008. http://resolver.caltech.edu/CaltechETD:etd-06022008-092549.

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Carson, Christian Tyler. "DNA viruses and the cellular DNA repair machinery /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3175282.

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Clever, Beate. "DNA repair in eukaryotes: the Rad54 recombinational repair protein /." [S.l : s.n.], 1996. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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Hoffbeck, Anne-Sophie. "Chromatin structure and DNA repair." Thesis, Strasbourg, 2013. http://www.theses.fr/2013STRAJ104/document.

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Notre génome est continuellement endommagé par des agents provoquant des lésions de l’ADN. Les cassures doubles brins de l’ADN (CDBs) sont les lésions les plus dangereuses. En effet, une CDB mal réparée peut mener à des aberrations de l’ADN pouvant conduire à l’apparition d’un cancer. Dans le but d’éviter les effets délétères des CDBs, nos cellules ont développé une voie de signalisation, nommée réponse aux dommages de l’ADN (RDA), permettant la détection des cassures et l’activation des points de contrôle du cycle cellulaire afin d’arrêter le cycle pendant la réparation des CDBs. Une des caractéristiques principales de la RDA est l’accumulation d’un grand nombre de facteurs sur l’ADN autour de la cassure, formant un foyer visible en microscopie. Cependant, l’efficacité de réparation de l’ADN est entravée par la structure condensée de la chromatine environnante. Les mécanismes de réparation de l’ADN surmontent ce problème en recrutant de nombreuses protéines permettant le réarrangement de la chromatine afin de faciliter la réparation. Le but de mon travail de thèse est d’identifier de nouvelles protéines impliquées dans le remodelage de la chromatine autour des CDBs. D’une part nous avons pour but d’identifier le protéome complet d’un foyer de réparation de l’ADN grâce à la technique PICh (Proteomics of Isolated Chromatin loci). D’autre part, nous étudions le rôle de l’oncoprotéine SET/TAF-1β, que nous avons identifié lors d’un criblage siRNA réalisé dans le but de découvrir de nouveaux facteurs chromatiniens impliqués dans la réparation des CDBs
Various DNA damaging agents, that can cause DNA lesions, assault constantly our genome. The most deleterious DNA lesions are the breaks occurring in both strands of DNA (Double stand breaks: DSBs). Inefficient repair of DSBs can lead to aberrations that may induce cancer. To avoid these deleterious effects of DSBs, cells have developed signalling cascades which entail detection of the lesions and spreading of the signal that leads to arrest in cell cycle progression and efficient repair. A major characteristic of DNA damage response (DDR) is the accumulation of a vast amount of proteins around the DSBs that are visible in the cell as DNA damage foci. However, efficient DNA repair is hampered by the fact that genomic DNA is packaged into chromatin. The DNA repair machinery overcomes this condensed structure to access damaged DNA by recruiting many proteins that remodel chromatin to facilitate efficient repair. The aim of my PhD work is to identify novel proteinsinvolved in the DDR and/or the remodelling of chromatin surrounding DSBs. On one hand, we take advantage of the PICh (Proteomics of Isolated Chromatin loci) technique and we aim to identify the entire proteome of DNA repair foci. On the other hand, we study the role of the oncogene SET/TAFIβ, a major hit of a siRNA screen performed to identify novel chromatin related proteins that play role in repair of DSBs
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Clark, Graeme T. "A study of DNA repair." Thesis, University of Southampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302000.

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Steffens, Laura Sione. "DNA repair in bacteroides fragilis." Master's thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/4337.

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Includes bibliographical leaves (leaves 89-101).
Bacteroides fragilis is a gut commensal in both humans and animals where it benefits the host through metabolizing indigestible compounds, stimulating the immune system and protecting against pathogen colonization. However, it is also an opportunistic pathogen, responsible for approximately half of anaerobic bacteraemias. Metronidazole is used to treat anaerobic infections. It diffuses into the celI as an inactive prodrug where it is reduced to form nitro anion and nitroso and hydroxylamine radicals. These chemically reactive compounds interact with DNA causing strand breaks and base mutations; the damage accumulates and leads to cell death. Mechanisms of metronidazole resistance in B. fragilis include decreased activity of oxidation/reduction enzymes, over-expression of multidrug efflux pumps and the conversion of metronidazole to non-toxic derivatives by nitroimidazole nitroreductases (encoded by nim genes). However, metronidazole resistance could also potentialIy be mediated by the over-expression or enhanced activity of DNA repair proteins. Thus, DNA repair in B. fragilis should be thoroughly investigated.
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Mackenney, Victoria Jane. "Human DNA ligase I in DNA replication and repair." Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267515.

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Gould, Poppy Aeron. "The role of DNA repair in DNA methylation dynamics." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/274360.

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The mammalian epigenome is globally reprogrammed at two stages of development; this involves the erasure and re-establishment of DNA methylation by both passive and active mechanisms, including DNA repair pathways, and occurs concurrently with an increase in developmental potency. In addition to Uhrf1 and the Tet enzymes, the interplay between activation induced cytidine deaminase (AID) and the DNA repair machinery has been implicated in epigenetic reprogramming of various in vivo and in vitro systems including mouse primordial germ cells, zygotes and induced pluripotent stem cells. AID deaminates cytosine to uracil and can also deaminate methylcytosine, whereas the primary role of UNG is to maintain the integrity of the genome through erasure of uracil. In this thesis, I have aimed to investigate the role of DNA repair in demethylation. To do this I have focused on the specific role of AID and UNG in the demethylation of a static system – primed serum ESCs and a dynamic system – serum to 2i (naïve) to epiblast-like ES cells. As the role of both AID and UNG involves genomic uracil, the central theme of my thesis is the impact of accumulation of uracil on DNA methylation levels in the genome. Therefore, my first aim was to develop a quantitative method to detect low levels of genomic uracil in DNA firstly, by mass spectrometry and secondly, by whole genome sequencing. In Chapter Three, I show that the impact of deamination during DNA preparation can be minimised, such that the level of genomic ESC uracil can be accurately determined as around 12,000 uracil per genome and that, as anticipated, Ung null ESCs have almost twice the genomic uracil content of wildtype ESCs. Secondly, I address the main question which is the impact of uracil accumulation on methylation levels. In order to do this, I generate two cell lines: Ung knockout and Aid over expressing, both of which should result in an increase in genomic uracil. I demonstrate that while over expression of Aid stimulates demethylation in static system and in a dynamic demethylating system, the impact of Ung knockout is less clear. In (static) serum ESCs, loss of Ung results in hypomethylation however, in order to transition to 2i (naïve) ESCs, a process which involves demethylation of the genome, it appears the Ung is required as loss of this gene inhibits proper demethylation. As such, I conclude that UNG-mediated DNA repair functions alongside passive demethylation, by reduction of UHRF1 levels, to demethylate 2i ESCs. To probe the mechanism by which accumulation of uracil in the genome alters methylation levels, I investigate the impact of Ung KO and Aid OE on global levels of DNA damage. I show that both cell lines have a greater incidence of double strand breaks compared to a wild type cell line, and accordingly, upregulate their DNA damage response pathway and the expression of certain repair genes. I suggest that increasing genomic levels of uracil causes genomic instability and that DNA demethylation occurs as a consequence of the repair of extensive DNA damage. More broadly, I suggest that ESCs are uniquely poised, due to their heightened DNA damage response, to use uracil as an intermediate of DNA demethylation. Interestingly, I also note that the biological impact on serum ESCs of loss of Ung appears to be an increase in pluripotency.
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Books on the topic "DNA repair"

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Balakrishnan, Lata, and Jason A. Stewart, eds. DNA Repair. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9500-4.

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Eckstein, Fritz, and David M. J. Lilley, eds. DNA Repair. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-48770-5.

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L, Campbell Judith, and Modrich Paul, eds. DNA repair. Amsterdam: Elsevier/Academic Press, 2006.

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L, Campbell Judith, and Modrich Paul, eds. DNA repair. Amsterdam: Elsevier/Academic Press, 2006.

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L, Campbell Judith, and Modrich Paul, eds. DNA repair. Amsterdam: Elsevier/Academic Press, 2006.

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Thomas, Allison E. DNA repair: Damage, repair mechanisms, and aging. Hauppauge, N.Y: Nova Science Publisher's, 2010.

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Vaughan, Pat. DNA Repair Protocols. New Jersey: Humana Press, 2000. http://dx.doi.org/10.1385/1592590683.

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Henderson, Daryl S. DNA Repair Protocols. New Jersey: Humana Press, 1999. http://dx.doi.org/10.1385/1592596754.

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Henderson, Daryl S., ed. DNA Repair Protocols. Totowa, NJ: Humana Press, 2006. http://dx.doi.org/10.1385/1592599737.

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Bjergbæk, Lotte, ed. DNA Repair Protocols. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-998-3.

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Book chapters on the topic "DNA repair"

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Bowater, R. "Eukaryotic DNA Ligases and DNA Repair." In DNA Repair, 301–14. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-48770-5_13.

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Baumstark-Khan, C. "DNA Repair." In Fundamentals for the Assessment of Risks from Environmental Radiation, 103–14. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4585-5_14.

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Borgmann, Kerstin, Sabrina Köcher, Malte Kriegs, Wael Yassin Mansour, Ann Christin Parplys, Thorsten Rieckmann, and Kai Rothkamm. "DNA Repair." In Molecular Radio-Oncology, 1–24. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-49651-0_1.

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Nicholson, Wayne L., and Ralf Moeller. "DNA Repair." In Encyclopedia of Astrobiology, 673–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-44185-5_452.

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Kelley, Mark R., and Leonard C. Erickson. "DNA Repair." In Basic Science of Cancer, 128–53. London: Current Medicine Group, 2000. http://dx.doi.org/10.1007/978-1-4684-8437-3_7.

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Nicholson, Wayne L., and Ralf Moeller. "DNA Repair." In Encyclopedia of Astrobiology, 451–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-11274-4_452.

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Lehman, I. Robert. "DNA Repair." In Molecular Life Sciences, 1–6. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_465-1.

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Plevani, Paolo. "DNA Repair." In Encyclopedia of Systems Biology, 610. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_725.

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Lehman, I. Robert. "DNA Repair." In Molecular Life Sciences, 236–40. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-1531-2_465.

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Nicholson, Wayne L., and Ralf Moeller. "DNA Repair." In Encyclopedia of Astrobiology, 1–3. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27833-4_452-3.

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Conference papers on the topic "DNA repair"

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Bono, Johann de. "Abstract PL03-01: Targeting DNA Repair and Defective DNA repair." In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-pl03-01.

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Wojtowicz, Damian, Mark D. M. Leiserson, Roded Sharan, and Teresa M. Przytycka. "DNA Repair Footprint Uncovers Contribution of DNA Repair Mechanism to Mutational Signatures." In Pacific Symposium on Biocomputing 2020. WORLD SCIENTIFIC, 2019. http://dx.doi.org/10.1142/9789811215636_0024.

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Chai, Juan, Yong-Ling Li, Lin Ma, and Jian-Qi Cui. "DNA Damage and Repair, Neurodegeneration and the Role of Purα in DNA Repair." In 2015 International Conference on Medicine and Biopharmaceutical. WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789814719810_0064.

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Bustin, R., and H. Messer. "Optimization criteria for DNA repair." In 2005 Microwave Electronics: Measurements, Identification, Applications. IEEE, 2005. http://dx.doi.org/10.1109/ssp.2005.1628815.

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Allione, Alessandra, Simonetta Guarrera, Silvia Polidoro, Fabio Rosa, Fulvio Ricceri, Floriana Voglino, Alessia Russo, et al. "Abstract 2739: DNA repair genotype-phenotype correlation and interplay between different DNA repair pathways." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-2739.

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"Structure and function evolution in DNA repair." In Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) :. Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences, 2022. http://dx.doi.org/10.18699/sbb-2022-610.

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Aggarwal, S., I. Ahmad, S. Gu, H. Paiste, M. N. Gillespie, and S. Matalon. "Mitochondrial DNA Repair Ameliorates Inhalation Lung Injury." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1020.

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Han, Chunhua, Ran Zhao, Jiang Qian, Nidhi Sharma, Gulzar Wani, Jinshan He, Qianzheng Zhu, Qi-En Wang, and Altaf A. Wani. "Abstract 5365: Cdt2-mediated XPG degradation promotes DNA repair synthesis following DNA damage excision in nucleotide excision repair." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-5365.

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Weninger, Keith R., Lauryn E. Sass, Vanessa C. DeRocco, Trevor Anderson, and Dorothy A. Erie. "DNA Repair Protein Dynamics through Single-Molecule Fluorescence." In Laser Science. Washington, D.C.: OSA, 2009. http://dx.doi.org/10.1364/ls.2009.lsthd3.

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Imam, J. S., J. Seashore, N. Tapryal, T. Hazra, and V. J. Cardenas. "DNA Base Excision Repair and Inflammation in COPD." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4736.

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Reports on the topic "DNA repair"

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Wilson, D. M. III. Functional characterization of dna repair proteins. Office of Scientific and Technical Information (OSTI), February 2000. http://dx.doi.org/10.2172/15001995.

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Sanchez-Ramos, Juan. Brain's DNA Repair Response to Neurotoxicants. Fort Belvoir, VA: Defense Technical Information Center, July 2005. http://dx.doi.org/10.21236/ada452374.

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Sanchez-Ramos, Juan. Brain's DNA Repair Response to Neurotoxicants. Fort Belvoir, VA: Defense Technical Information Center, January 2007. http://dx.doi.org/10.21236/ada467590.

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Helzlsouer, Kathy J. DNA Repair and Breast Cancer Risk. Fort Belvoir, VA: Defense Technical Information Center, October 1999. http://dx.doi.org/10.21236/ada382979.

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Phoebe L. Stewart. Cryo-EM Imaging of DNA-PK DNA Damage Repair Complexes. Office of Scientific and Technical Information (OSTI), June 2005. http://dx.doi.org/10.2172/841088.

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Wilson, David. Repair Machinery for Radiation-Induced DNA Damage. Fort Belvoir, VA: Defense Technical Information Center, July 2001. http://dx.doi.org/10.21236/ada396847.

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Walker, Graham C. Final report [DNA Repair and Mutagenesis - 1999]. Office of Scientific and Technical Information (OSTI), May 2001. http://dx.doi.org/10.2172/807345.

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Thompson, Lawrence H. Repair Machinery for Radiation-Induced DNA Damage. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada407373.

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Henning, Susanne. Flavonoids and DNA Repair in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, December 2005. http://dx.doi.org/10.21236/ada448584.

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Henning, Susanne M. Flavonoids and DNA Repair in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, December 2004. http://dx.doi.org/10.21236/ada434003.

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