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Journal articles on the topic 'DMS'

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Author: Grafiati

Published: 4 June 2021

Last updated: 20 February 2023

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1

Roberts, N. J., H. R. Burton, and G. A. Pitson. "Volatile organic compounds from Organic Lake, an Antarctic, hypersaline, meromictic lake." Antarctic Science 5, no. 4 (December 1993): 361–66. http://dx.doi.org/10.1017/s0954102093000483.

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Five volatile organic compounds were identified throughout 1991 in the hypolimnion of Organic Lake. These were dimethylsulphide (DMS), dimethyldisulphide (DM2S), dimethyltrisulphide (DM3S), dimethyltetrasulphide (DM4S) and phenol. The concentration of these compounds increased with lake depth. The concentration of DMS and DM2S was higher in the sediment than in the water column. Carbon disulphide occurred only in the sediment. DMS was the only volatile organic compound detected in the epilimnion of the lake, where its concentration increased from winter onwards. The source of DMS was not dimethylsulphoniopropionate (DMSP). This was determined by hydroxylation of the sample with NaOH. There was no change in the concentration of DMS but the concentration of DM2S increased dramatically while the concentrations of DM3S and DM4S decreased concomitantly. This has important implications in the estimation of DMS derived from DMSP by hydroxylation when organic polysulphides are also present. The stability of the hypolimnion of Organic Lake was reflected by the lack of change in temperature, density, redox potential and the relatively constant concentration of volatile organic compounds throughout the year. Potential sources of the volatile organic compounds are discussed in relation to the isolated nature of the lake.

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2

Visconti, Virginia Veronica, Federica Centofanti, Simona Fittipaldi, Elisa Macrì, Giuseppe Novelli, and Annalisa Botta. "Epigenetics of Myotonic Dystrophies: A Minireview." International Journal of Molecular Sciences 22, no. 22 (November 22, 2021): 12594. http://dx.doi.org/10.3390/ijms222212594.

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Myotonic dystrophy type 1 and 2 (DM1 and DM2) are two multisystemic autosomal dominant disorders with clinical and genetic similarities. The prevailing paradigm for DMs is that they are mediated by an in trans toxic RNA mechanism, triggered by untranslated CTG and CCTG repeat expansions in the DMPK and CNBP genes for DM1 and DM2, respectively. Nevertheless, increasing evidences suggest that epigenetics can also play a role in the pathogenesis of both diseases. In this review, we discuss the available information on epigenetic mechanisms that could contribute to the DMs outcome and progression. Changes in DNA cytosine methylation, chromatin remodeling and expression of regulatory noncoding RNAs are described, with the intent of depicting an epigenetic signature of DMs. Epigenetic biomarkers have a strong potential for clinical application since they could be used as targets for therapeutic interventions avoiding changes in DNA sequences. Moreover, understanding their clinical significance may serve as a diagnostic indicator in genetic counselling in order to improve genotype–phenotype correlations in DM patients.

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3

Waldorf, Manuel, Martin Cordes, Silja Vocks, and Don McCreary. "„Ich wünschte, ich wäre muskulöser”: Eine teststatistische Überprüfung der deutschsprachigen Fassung der Drive for Muscularity Scale (DMS)." Diagnostica 60, no. 3 (July 2014): 140–52. http://dx.doi.org/10.1026/0012-1924/a000106.

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Die Drive for Muscularity Scale (DMS) ist der am häufigsten verwendete Fragebogen zur Erfassung des Muskulositätsstrebens. Ziel der Studie war die psychometrische Überprüfung der deutschsprachigen Version der DMS. 601 Männer aus muskel- und kraftorientierten Sportarten wurden am Computer oder mit der Papierversion der DMS und mit weiteren Skalen befragt. Interne Konsistenz und Retest-Reliabilität der DMS liegen im sehr guten Bereich (>.88), ebenso die Korrelation mit einem Alternativtest (Male Body Attitudes Scale: .81). Muskulositäts- und Schlankheitsstreben lassen sich eindeutig differenzieren (Eating Disorder Inventory-2-DT: .11). Die durchgeführten Faktorenanalysen stützen die Einteilung in eine kognitive und eine korrelierte behaviorale Subskala. Es zeigten sich Zusammenhänge mit körperbezogenem Selbstwert und körperdysmorphen Sorgen. Die deutschsprachige DMS ist ein reliables und valides Instrument zur Erfassung des Muskulositätsstrebens in Forschung und klinischer Einzelfallanwendung.

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4

Roche, Brian M., Tom M. Vinci, Michael A. Hawk, Craig R. Hassler, David T. Pressburger, Merrill R. Osheroff, Glenn D. Ritchie, and Brian L. Burback. "MMB4 DMS." International Journal of Toxicology 32, no. 4_suppl (July 2013): 49S—58S. http://dx.doi.org/10.1177/1091581813488632.

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The objectives of these studies were to determine the cardiopulmonary effects of a single intramuscular administration of 1,1′-methylenebis[4-[(hydroxyimino)methyl]-pyridinium] dimethanesulfonate (MMB4 DMS) on dogs and on the central nervous system in rats. On days 1, 8, 15, and 22, male and female dogs received either vehicle (water for injection/0.5% benzyl alcohol/methane sulfonic acid) or MMB4 DMS (20, 50, or 100 mg/kg). Pulmonary function was evaluated for the first 5 hours after concurrent dosing with cardiovascular monitoring; then cardiovascular monitoring continued for 72 hours after dosing. Rats were dosed once by intramuscular injection with vehicle (water for injection/0.5% benzyl alcohol/methane sulfonic acid) or MMB4 DMS (60, 170, or 340 mg/kg). In dogs, 100 mg/kg MMB4 DMS resulted in increased blood pressure, slightly increased heart rate, slightly prolonged corrected QT, and moderately increased respiratory rate. There were no toxicological effects of MMB4 DMS on neurobehavioral function in rats administered up to 340 mg/kg MMB4 DMS.

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5

Yu, Xiaoxuan, Shijie Chen, and Qiang Shan. "Depression in the Direct Pathway of the Dorsomedial Striatum Permits the Formation of Habitual Action." Cerebral Cortex 31, no. 7 (March 29, 2021): 3551–64. http://dx.doi.org/10.1093/cercor/bhab031.

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Abstract In order to achieve optimal outcomes in an ever-changing environment, humans and animals generally manage their action control via either goal-directed action or habitual action. These two action strategies are thought to be encoded in distinct parallel circuits in the dorsal striatum, specifically, the posterior dorsomedial striatum (DMS) and the dorsolateral striatum (DLS), respectively. The striatum is primarily composed of two subtypes of medium spiny neurons (MSNs): the direct-pathway striatonigral and the indirect-pathway striatopallidal MSNs. MSN-subtype-specific synaptic plasticity in the DMS and the DLS has been revealed to underlie goal-directed action and habitual action, respectively. However, whether any MSN-subtype-specific synaptic plasticity in the DMS is associated with habitual action, and if so, whether the synaptic plasticity affects the formation of habitual action, are not known. This study demonstrates that postsynaptic depression in the excitatory synapses of the direct-pathway striatonigral MSNs in the DMS is formed after habit learning. Moreover, chemogenetically rescuing this depression compromises the acquisition, but not the expression, of habitual action. These findings reveal that an MSN-subtype-specific synaptic plasticity in the DMS affects habitual action and suggest that plasticity in the DMS as well as in the DLS contributes to the formation of habitual action.

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6

Crible, Ludivine. "Discourse markers and (dis)fluency in English and French." International Journal of Corpus Linguistics 22, no. 2 (September 22, 2017): 242–69. http://dx.doi.org/10.1075/ijcl.22.2.04cri.

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Abstract While discourse markers (DMs) and (dis)fluency have been extensively studied in the past as separate phenomena, corpus-based research combining large-scale yet fine-grained annotations of both categories has, however, never been carried out before. Integrating these two levels of analysis, while methodologically challenging, is not only innovative but also highly relevant to the investigation of spoken discourse in general and form-meaning patterns in particular. The aim of this paper is to provide corpus-based evidence of the register-sensitivity of DMs and other disfluencies (e.g. pauses, repetitions) and of their tendency to combine in recurrent clusters. These claims are supported by quantitative findings on the variation and combination of DMs with other (dis)fluency devices in DisFrEn, a richly annotated and comparable English-French corpus representative of eight different interaction settings. The analysis uncovers the prominent place of DMs within (dis)fluency and meaningful association patterns between forms and functions, in a usage-based approach to meaning-in-context.

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7

Amano, Mutsuki, Yoko Kanazawa, Kei Kozawa, and Kozo Kaibuchi. "Identification of the Kinase-Substrate Recognition Interface between MYPT1 and Rho-Kinase." Biomolecules 12, no. 2 (January 18, 2022): 159. http://dx.doi.org/10.3390/biom12020159.

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Protein kinases exert physiological functions through phosphorylating their specific substrates; however, the mode of kinase–substrate recognition is not fully understood. Rho-kinase is a Ser/Thr protein kinase that regulates cytoskeletal reorganization through phosphorylating myosin light chain (MLC) and the myosin phosphatase targeting subunit 1 (MYPT1) of MLC phosphatase (MLCP) and is involved in various diseases, due to its aberrant cellular contraction, morphology, and movement. Despite the importance of the prediction and identification of substrates and phosphorylation sites, understanding of the precise regularity in phosphorylation preference of Rho-kinase remains far from satisfactory. Here we analyzed the Rho-kinase–MYPT1 interaction, to understand the mode of Rho-kinase substrate recognition and found that the three short regions of MYPT1 close to phosphorylation sites (referred to as docking motifs (DMs); DM1 (DLQEAEKTIGRS), DM2 (KSQPKSIRERRRPR), and DM3 (RKARSRQAR)) are important for interactions with Rho-kinase. The phosphorylation levels of MYPT1 without DMs were reduced, and the effects were limited to the neighboring phosphorylation sites. We further demonstrated that the combination of pseudosubstrate (PS) and DM of MYPT1 (PS1 + DM3 and PS2 + DM2) serves as a potent inhibitor of Rho-kinase. The present information will be useful in identifying new substrates and developing selective Rho-kinase inhibitors.

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8

Yang, Liu, Qiang Han, Shuya Cao, Junchao Yang, Jiang Zhao, and Mingyu Ding. "Hyphenated differential mobility spectrometry for rapid separation and detection." Reviews in Analytical Chemistry 35, no. 1 (April 1, 2016): 29–40. http://dx.doi.org/10.1515/revac-2015-0017.

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AbstractThis paper reviews hyphenated differential mobility spectrometry (DMS) technology. DMS is a type of ion mobility spectrometry (IMS) also called high-field asymmetric waveform IMS. It is widely used in the detection of chemical warfare agents, explosives, drugs, and volatile organic compounds. Stand-alone DMS analysis of complex mixtures in real-field applications is challenging. Hyphenated DMS can improve resolution for rapid separation and detection. This review focuses on hyphenated DMS, including gas chromatography-DMS, DMS-mass spectrometry (MS), DMS-IMS, IMS-DMS, and DMS-DMS, as well as their associated principles, applications, and research procedures. Key problems in hyphenated DMS are considered.

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9

Pemp, Berthold, Sabine Koinig, Karl Kircher, Christoph Mitsch, and Andreas Reitner. "Vertikale Blickparesen bei dorsalem Mittelhirnsyndrom und anderen Erkrankungen." Spektrum der Augenheilkunde 35, no. 1 (January 13, 2021): 36–43. http://dx.doi.org/10.1007/s00717-021-00482-w.

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Zusammenfassung Hintergrund Die vertikale Blickparese (vBP) ist ein typisches Symptom bei Läsionen des dorsalen Mittelhirns. Die klinische Ausprägung der vBP kann dabei stark variieren und im Rahmen eines dorsalen Mittelhirnsyndroms (DMS) mit zusätzlichen Symptomen wie einer Konvergenzparese, einem Konvergenzretraktionsnystagmus, einer verminderten Pupillenreaktion oder einer Skew Deviation vergesellschaftet sein. Je nach Lokalisation und Größe der Läsion kann auch eine Kombination mit weiteren zentralen Motilitätsstörungen vorliegen. Material und Methode Im Rahmen einer retrospektiven Studie wurden die Patientendaten unserer neuroophthalmologischen Ambulanz über einen Zeitraum von 25 Jahren nach Fällen mit Einschränkungen konjugierter vertikaler Augenbewegungen durchsucht und hinsichtlich ihrer neuroorthoptischen Befunde und Ätiologien ausgewertet. Resultate Es wurden 202 Patienten mit vBP identifiziert. Das Befundspektrum reichte von einer isolierten Sakkadenstörung nur nach oben bis hin zum kompletten Ausfall aller willkürlichen und reflektorischen vertikalen Augenbewegungen. Nur 12 vBP lagen isoliert vor. Ursächlich war bei 155 Patienten ein DMS, wovon aber nur 18 Fälle dem von Parinaud geprägten Syndrombild (vBP + Konvergenzparese ± Pupillenstörung ohne weitere Symptome) entsprachen; 42 Patienten mit DMS zeigten lediglich eine Sakkadenparese. Der Aufblick war bei DMS insgesamt mehr eingeschränkt als der Abblick. Die häufigsten Begleitsymptome waren eine Konvergenzparese (49 %), Konvergenznystagmus (40 %), Pupillenstörung (32 %), Skew Deviation (21 %) und Blickrichtungsnystagmus (15 %). In 58 Fällen traten weitere zentrale Okulomotorikstörungen auf. Bis zum 18. Lebensjahr war eine vBP bei 58 % der Patienten durch Gehirntumoren bedingt, wohingegen nach dem 60. Lebensjahr neben einem DMS durch Infarkte (41 %) v. a. degenerative Erkrankungen (44 %) ursächlich waren. Schlussfolgerungen Langsame und schnelle Augenbewegungen nach oben und unten werden im Hirnstamm unterschiedlich generiert, geleitet und integriert und können daher bei Läsionen des Mittelhirns verschieden stark gestört sein. Die Ergebnisse verdeutlichen zudem die enge Lagebeziehung der Zentren für vertikale Augenbewegungen, Konvergenz und Pupillenreaktion im dorsalen Mittelhirn. Die Kombination einer vBP mit weiteren neuroophthalmologischen Diagnosen kann daher eine topografische und ätiologische Zuordnung erleichtern.

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10

Maffioleti Cavaler, Camila, and Samira Mafioletti Macarini. "Repensando práticas: delegacias da mulher enquanto espaço dialógico de prevenção à violência conjugal." Nova Perspectiva Sistêmica 29, no. 66 (April 1, 2020): 60–73. http://dx.doi.org/10.38034/nps.v29i66.516.

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Neste estudo, trata-se de um ensaio teórico cujo objetivo é discutir o papel das delegacias especializadas de atendimento à mulher (DMs), a partir do olhar da Psicologia com enfoque de gênero, reflexivo e sistêmico. As DMs desenvolvem procedimentos relativos à apuração de infrações cometidas mediante violência doméstica ou familiar, nos termos da Lei 11.340/2006. No entanto, neste artigo buscase enfatizar as DMs também como um espaço de fortalecimento das medidas integradas de prevenção a esse tipo de violência, trazendo foco para o eixo preventivo instituído pela referida lei. Para tanto, foi discutida a complexidade do fenômeno da violência conjugal, bem como apresentadas algumas possibilidades de atuação policial, baseadas na segurança cidadã, que promovam discussões sobre a complexidade da violência conjugal e os processos culturais que a naturalizam. Entende-se, ainda, que estes serviços só podem ser oferecidos a partir da capacitação continuada dos/as policiais que atuam nas DMs.

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11

Butler, Barbara E. "DMS contract awards." Government Publications Review 15, no. 5 (September 1988): 487–88. http://dx.doi.org/10.1016/0277-9390(88)90114-8.

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12

Kirillov, Andrey, and Valeriy Yarygin. "A modern data measurement system to study and test thermionic heat to electricity converters." Nuclear Energy and Technology 4, no. 3 (December 7, 2018): 179–83. http://dx.doi.org/10.3897/nucet.4.31867.

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Studies and tests are conducted to determine the performance of thermionic nuclear power plants (TNPP) a stage in which is pre-irradiation testing of laboratory thermionic converters (TIC) with flat and cylindrically shaped electrodes using test facilities fitted with automated data measurement systems (DMS). The TIC volt-ampere characteristics (VAC) are measured in the DMS jointly with the measured test section and experimental test facility temperature fields. The structure and the characteristics of a DMS based on products from ICP DAS Co., Ltd are presented. A developed VAC measurement program providing the operator with a convenient graphic interface and enabling adjustment of the measurement parameters has been considered. The VAC recording errors in the process of measurements have been determined using TIC simulators. The error in the VAC diffusion portion on a simulator (with a current of less than 3 A) is not more than 1%. Thanks to the use of modern components, the developed DMS offers extended functional capabilities for measuring the thermocouple signals in an experimental electrophysical test facility. The DMS structure provides for the convenience of scaling (through a larger number of measuring channels) and makes it possible to add modules from other manufacturers. The experience of operating this DMS will be used to develop the DMS for an in-pile test system designed for similar functions.

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Araújo, R. A., R. C. Rodrigues, C. S. Costa, F. N. S. Santos, C. O. Costa, and I. R. Silva. "Capacidade de suporte mínima para desenvolvimento da microbiota ruminal." Archivos de Zootecnia 68, no. 263 (July 15, 2019): 342–47. http://dx.doi.org/10.21071/az.v68i263.4191.

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Foi avaliada a degradabilidade in situ da matéria seca (DMS) de duas cultivares de Urochloa brizantha cvs. Xaraés e Piatã em seus respectivos componentes: folhas e haste, no mesmo período de incubação de 6 horas e a diferentes níveis de suplementação com concentrado com base na porcentagem de peso vivo (PV) animal. O delineamento experimental utilizado foi o inteiramente casualizado com quatro repetições em arranjo fatorial 4x2 (quatro níveis de concentrado na dieta animal 0,0%, 0,33%, 0,67% e 1,0% PV por duas cultivares de Urochloa brizantha). Foi observado que o DMS das folhas de capim Piatã não diferiu quando o animal consumiu o concentrado em níveis 0,0%, 0,33% e 0,67%, para as hastes, o nível de 0,00% PV apresentou menor DMS. As folhas do capim Xaraés apresentaram menor DMS no consumo de concentrado em 1,0% PV e no colmo os maiores valores foram nos níveis 0,00 %, 0,33 % e 0,67% PV. Realizada a equação de regressão foram obtidos maiores valores de concentrado aliados a maior DMS das forrageiras. Para a haste do capim Xaraés o nível ideal de suplementação foi 0,38% do PV de concentrado. Já para as folhas este valor foi 0,41% PV. Para o capim Piatã, os valores de folha e colmo foram de 0,62% e 0,44% PV, respectivamente.

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14

Marques, Daniela Giffoni, Lindolfo Storck, Sidinei José Lopes, and Thomas Newton Martin. "Qualidade dos ensaios de competição de cultivares de milho no Estado do Rio Grande do Sul." Ciência Rural 30, no. 3 (June 2000): 381–85. http://dx.doi.org/10.1590/s0103-84782000000300001.

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O objetivo deste trabalho foi estimar a proporção de ensaios com significância para efeito de blocos, cultivares e do atendimento às pressuposições de normalidade e aleatoriedade do erro, homogeneidade das variâncias do erro entre cultivares e a aditividade do modelo necessárias para os testes de hipótese. Também foi objetivo a quantificação do efeito do não atendimento das pressuposições sobre a diferença mínima significativa (DMS), obtida pelo teste de Tukey em nível de 5% de probabilidade. Foram analisados 307 ensaios da rede estadual de competição de cultivares de milho do Estado do Rio Grande do Sul no período de 1993 e 1996. Dos ensaios de competição de cultivares de milho, 85,67% apresentaram efeito significativo para cultivares e, nestes, a média da DMS era igual a 30,28%. O não atendimento às pressuposições para os testes de hipótese ocorreu em baixa freqüência e aumentou a DMS. A falta de aditividade no modelo ocorreu em 8,75% dos ensaios e não modificou a DMS, sendo a transformação indicada ineficiente para a redução da DMS. A causa da falta de aleatoriedade dos erros em 9,88% dos ensaios foi a variabilidade entre as unidades experimentais e/ou o bloqueamento em posição inadequada à variabilidade espacial da fertilidade no local do ensaio.

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15

Stutey, Diane M., Jenny L. Cureton, Kim Severn, and Matthew Fink. "Suicide Protective Factors: Utilizing SHORES in School Counseling." Professional Counselor 11, no. 1 (March 2021): 16–30. http://dx.doi.org/10.15241/dms.11.1.16.

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Recently, a mnemonic device, SHORES, was created for counselors to utilize with clients with suicidal ideation. The acronym of SHORES stands for Skills and strategies for coping (S); Hope (H); Objections (O); Reasons to live and Restricted means (R); Engaged care (E); and Support (S). In this manuscript, SHORES is introduced as a way for school counselors to address protective factors against suicide. In addition, the authors review the literature on comprehensive school suicide prevention and suicide protective factors; describe the relevance of a suicide protective factors mnemonic that school counselors can use; and illustrate the mnemonic’s application in classroom guidance, small-group, and individual settings.

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16

"DMS est en deuil..." Distances et médiations des savoirs, no. 23 (August 9, 2018). http://dx.doi.org/10.4000/dms.2623.

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Vidal, Martine, Monique Grandbastien, and Pierre Mœglin. "Aux collaborateurs de DMS." Distances et médiations des savoirs 1, no. 4 (September 22, 2013). http://dx.doi.org/10.4000/dms.441.

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18

"DMS." Cold Spring Harbor Protocols 2006, no. 11 (May 1, 2006): pdb.caut2183. http://dx.doi.org/10.1101/pdb.caut2183.

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"DMS." Cold Spring Harbor Protocols 2006, no. 11 (May 1, 2006): pdb.caut356. http://dx.doi.org/10.1101/pdb.caut356.

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20

Pellicciari, Carlo. "MYOTONIC DYSTROPHIES: GENETICALLY-BASED DISEASES DUE TO TOXIC RNA." Istituto Lombardo - Accademia di Scienze e Lettere - Incontri di Studio, January 24, 2014, 5–8. http://dx.doi.org/10.4081/incontri.2012.57.

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Myotonic dystrophies (DMs, the second most diffuse forms of muscular dystrophy, after Duchenne dystrophy) are genetically-based degenerative neuromuscular diseases exhibiting widely variable clinical features and characterized by myotonia (i.e., a prolonged contraction of skeletal muscles after short stimulation) and a delayed muscle relaxation after voluntary contraction. There are two form of DMs: the more severe DM1 (or Steinert’s disease), and the milder form DM2. The intranuclear accumulation of expanded RNAs is considered as the pathogenetic factor of DMs: the presence of these RNAs exerts a toxic action on cell function which essentially depends on the ectopic sequestration of nuclear protein factors involved in the processing of transcripts. The aim of this mini-symposium is to describe the genetic and cellular bases of DMs, showing how the results of basic research may provide important clues for both diagnosis and therapy.

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"Aux experts et relecteurs de DMS." Distances et médiations des savoirs 3, no. 12 (December 15, 2015). http://dx.doi.org/10.4000/dms.1198.

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DMS, Conseil scientifique de. "Aux experts et relecteurs de DMS." Distances et médiations des savoirs, no. 16 (December 10, 2016). http://dx.doi.org/10.4000/dms.1604.

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"Aux experts et relecteurs de DMS." Distances et médiations des savoirs 2017, no. 20 (December 16, 2017). http://dx.doi.org/10.4000/dms.2074.

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"Aux experts et relecteurs de DMS." Distances et médiations des savoirs, no. 24 (December 17, 2018). http://dx.doi.org/10.4000/dms.3282.

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"Aux experts et relecteurs de DMS." Distances et médiations des savoirs 37, no. 37 (March 15, 2022). http://dx.doi.org/10.4000/dms.7694.

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26

Vandaele, Youna, Nagaraj R. Mahajan, David J. Ottenheimer, Jocelyn M. Richard, Shreesh P. Mysore, and Patricia H. Janak. "Distinct recruitment of dorsomedial and dorsolateral striatum erodes with extended training." eLife 8 (October 17, 2019). http://dx.doi.org/10.7554/elife.49536.

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Hypotheses of striatal orchestration of behavior ascribe distinct functions to striatal subregions, with the dorsolateral striatum (DLS) especially implicated in habitual and skilled performance. Thus neural activity patterns recorded from the DLS, but not the dorsomedial striatum (DMS), should be correlated with habitual and automatized performance. Here, we recorded DMS and DLS neural activity in rats during training in a task promoting habitual lever pressing. Despite improving performance across sessions, clear changes in corresponding neural activity patterns were not evident in DMS or DLS during early training. Although DMS and DLS activity patterns were distinct during early training, their activity was similar following extended training. Finally, performance after extended training was not associated with DMS disengagement, as would be predicted from prior work. These results suggest that behavioral sequences may continue to engage both striatal regions long after initial acquisition, when skilled performance is consolidated.

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Choi, Sanghoon, Yijuan Du, David L. Wokosin, and Steven M. Graves. "Acute and protracted abstinence from methamphetamine bidirectionally changes intrinsic excitability of indirect pathway spiny projection neurons in the dorsomedial striatum." Scientific Reports 12, no. 1 (July 15, 2022). http://dx.doi.org/10.1038/s41598-022-16272-6.

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AbstractMethamphetamine (meth) is an addictive psychostimulant and illicit use presents significant personal and socioeconomic harm. Behavioral studies support the involvement of the dorsal striatum in drug-seeking but stimulant induced dysfunction in this region is understudied. The dorsal striatum can be subdivided into the dorsomedial (DMS) and dorsolateral (DLS) striatum with the DMS implicated in goal-directed and DLS in habitual behaviors; both regions are primarily composed of GABAergic direct (dSPNs) and indirect pathway (iSPNs) spiny projection neurons. To examine the effect of repeated meth on SPNs, mice were administered meth (2 mg/kg) for ten consecutive days and intrinsic excitability, dendritic excitability, and spine density were examined. DMS iSPN intrinsic excitability was increased at 1 day but decreased at 21 days of abstinence. In contrast, DMS dSPN intrinsic excitability was unchanged at either timepoint. Dendritic excitability and spine densities were unaltered in DMS iSPNs and dSPNs at 1 and 21 days of abstinence. The effect of repeated meth on iSPN excitability was specific to the DMS; DLS iSPN intrinsic excitability, dendritic excitability, and spine density were unchanged at 1 and 21 days of abstinence. These findings point toward DMS iSPN dysfunction in meth use disorders with differential dysfunction dependent on abstinence duration.

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Miguet, Mathilde, and Françoise Paquienséguy. "DMS-DMK aujourd’hui ? Enquête de lectorat 2021." Distances et médiations des savoirs 39, no. 39 (October 13, 2022). http://dx.doi.org/10.4000/dms.8073.

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"DMS buffer." Cold Spring Harbor Protocols 2006, no. 1 (June 2006): pdb.rec8986. http://dx.doi.org/10.1101/pdb.rec8986.

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V., Yokesh, Gulam Nabi Alsath, and Malathi Kanagasabai. "Defected microstrip structure-based near-end and far-end crosstalk mitigation in high-speed PCBs for mixed signals." Microelectronics International, December 7, 2022. http://dx.doi.org/10.1108/mi-05-2022-0089.

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Purpose The design, fabrication and experimental validation of defected microstrip structure (DMS) are proposed to address the problem of near-end crosstalk (NEXT) and far-end crosstalk (FEXT) between the microstrip transmission lines in a printed circuit board. Design/methodology/approach The proposed DMS evolved with the combination of spur line (L-shaped DMS) and U-shaped DMS topologies. This technique reduces the strength of electromagnetic coupling and suppresses crosstalk by optimizing the capacitive and inductive coupling ratio between the linked microstrip lines. The practical inductance value is much more significant in DMS than in defected ground structures (DGS), but the capacitance value remains the same. Findings A DMS unit is etched on the aggressor microstrip line instead of the DGS circuit. Because there is no leakage via the ground plane and the circuit size is far smaller than with DGS, the enclosure issue is disregarded. DMS structures have a larger effective inductance and are resistant to electromagnetic interference. A tightly coupled transmission line structure with minimal separation between the coupled microstrip line is designed using DMS. Further research must be conducted to improve the NEXT, FEXT and spacing between the transmission lines. Originality/value Simulation and actual measurement results show that the proposed DMS structure can effectively suppress crosstalk by analysing the S-parameters, namely, S_12, S_13 and S_14, with measured values of 1.48 dB, 20.65 dB and 21.099 dB, respectively. The data rate is measured to be 1.34 Gbps as per the eye diagram characterization. The results show that the NEXT and FEXT are reduced by approximately 20 dB in the frequency range of 1–11 GHz for mixed signals. The substantial measured results in the vector network analyser coincide with the computer simulation technology microwave studio suite simulation results.

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"Dimethyl sulfate (DMS)." Cold Spring Harbor Protocols 2006, no. 1 (June 2006): pdb.caut340. http://dx.doi.org/10.1101/pdb.caut340.

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32

"DMS stop buffer." Cold Spring Harbor Protocols 2009, no. 9 (September 1, 2009): pdb.rec11960. http://dx.doi.org/10.1101/pdb.rec11960.

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33

"DMS stop solution." Cold Spring Harbor Protocols 2006, no. 1 (June 2006): pdb.rec8987. http://dx.doi.org/10.1101/pdb.rec8987.

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Fritz, Brandon M., Fuqin Yin, and Brady K. Atwood. "Input-selective adenosine A1 receptor-mediated synaptic depression of excitatory transmission in dorsal striatum." Scientific Reports 11, no. 1 (March 18, 2021). http://dx.doi.org/10.1038/s41598-021-85513-x.

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AbstractThe medial (DMS) and lateral (DLS) dorsal striatum differentially drive goal-directed and habitual/compulsive behaviors, respectively, and are implicated in a variety of neuropsychiatric disorders. These subregions receive distinct inputs from cortical and thalamic regions which uniquely determine dorsal striatal activity and function. Adenosine A1 receptors (A1Rs) are prolific within striatum and regulate excitatory glutamate transmission. Thus, A1Rs may have regionally-specific effects on neuroadaptive processes which may ultimately influence striatally-mediated behaviors. The occurrence of A1R-driven plasticity at specific excitatory inputs to dorsal striatum is currently unknown. To better understand how A1Rs may influence these behaviors, we first sought to understand how A1Rs modulate these distinct inputs. We evaluated A1R-mediated inhibition of cortico- and thalamostriatal transmission using in vitro whole-cell, patch clamp slice electrophysiology recordings in medium spiny neurons from both the DLS and DMS of C57BL/6J mice in conjunction with optogenetic approaches. In addition, conditional A1R KO mice lacking A1Rs at specific striatal inputs to DMS and DLS were generated to directly determine the role of these presynaptic A1Rs on the measured electrophysiological responses. Activation of presynaptic A1Rs produced significant and prolonged synaptic depression (A1R-SD) of excitatory transmission in the both the DLS and DMS of male and female animals. Our findings indicate that A1R-SD at corticostriatal and thalamostriatal inputs to DLS can be additive and that A1R-SD in DMS occurs primarily at thalamostriatal inputs. These findings advance the field’s understanding of the functional roles of A1Rs in striatum and implicate their potential contribution to neuropsychiatric diseases.

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Croze, Emmanuelle. "Covid-19 et passage éclair au distanciel pour les enseignants de langues vivantes du secondaire : une expérience renvoyant à l’irréductible présence en classe de langue." Distances et médiations des savoirs, no. 33 (March 15, 2021). http://dx.doi.org/10.4000/dms.6134.

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Grandbastien, Monique. "Quelles plateformes pour accompagner la digitalisation des organismes de formation continue ?" Distances et médiations des savoirs, no. 33 (March 15, 2021). http://dx.doi.org/10.4000/dms.6224.

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Nkwanui, Benjamin, Séverine Colinet, and Pascale Haag. "Contrôlabilité d’un dispositif mobile via WhatsApp : amélioration des performances des apprenants." Distances et médiations des savoirs, no. 33 (March 15, 2021). http://dx.doi.org/10.4000/dms.6028.

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Granjon, Yves. "La perception de l’enseignement à distance par les étudiants en situation de confinement : premières données." Distances et médiations des savoirs, no. 33 (March 15, 2021). http://dx.doi.org/10.4000/dms.6166.

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Grandbastien, Monique, Pierre Mœglin, and Daniel Peraya. "Éditorial." Distances et médiations des savoirs, no. 33 (March 15, 2021). http://dx.doi.org/10.4000/dms.6221.

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Peraya, Daniel. "S’intéresser aux acteurs de l’ingénierie et de l’accompagnement pédagogique." Distances et médiations des savoirs, no. 33 (March 15, 2021). http://dx.doi.org/10.4000/dms.6211.

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Andre, Frédéric, Galaup Michel, Jean-Michel Caire, and Laurence Dantan. "La visioconférence pour la transmission des savoirs théoriques des kinésithérapeutes." Distances et médiations des savoirs, no. 33 (March 15, 2021). http://dx.doi.org/10.4000/dms.6083.

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Peltier, Claire. "Thésographie sélective 2020." Distances et médiations des savoirs, no. 33 (March 15, 2021). http://dx.doi.org/10.4000/dms.6216.

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Brudermann, Cédric, and Nicole Poteaux. "Langues pour étudiants spécialistes d’autres disciplines : de l’amphithéâtre à l’autonomie d’apprentissage." Distances et médiations des savoirs 3, no. 9 (March 17, 2015). http://dx.doi.org/10.4000/dms.1003.

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Loizon, Anaïs, and Patrick Mayen. "Le cours magistral en amphithéâtre : une situation d’enseignement perturbée par les instruments." Distances et médiations des savoirs 3, no. 9 (March 17, 2015). http://dx.doi.org/10.4000/dms.1004.

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Papi, Cathia, and Viviane Glikman. "Les étudiants entre cours magistraux et usage des TIC." Distances et médiations des savoirs 3, no. 9 (March 17, 2015). http://dx.doi.org/10.4000/dms.1012.

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Assude, Teresa. "Potentiel et obstacles à l’appropriation d’un parcours de formation « hybride »." Distances et médiations des savoirs 1, no. 1 (December 12, 2012). http://dx.doi.org/10.4000/dms.103.

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Cerisier, Jean-François. "La pédagogie universitaire à l’heure du numérique – Questionnement et éclairage de la recherche." Distances et médiations des savoirs 3, no. 10 (June 22, 2015). http://dx.doi.org/10.4000/dms.1038.

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Dussarps, Clément. "L’abandon en formation à distance." Distances et médiations des savoirs 3, no. 10 (June 22, 2015). http://dx.doi.org/10.4000/dms.1039.

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Ferone, Georges, and Aurore Lavenka. "La classe virtuelle, quels effets sur la pratique de l’enseignant ?" Distances et médiations des savoirs 3, no. 10 (June 22, 2015). http://dx.doi.org/10.4000/dms.1047.

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Gélis, Jean-Michel. "Des responsables d’équipe dans le déploiement d’un enseignement à distance : entre innovation, industrialisation et modèles de dissémination." Distances et médiations des savoirs 3, no. 10 (June 22, 2015). http://dx.doi.org/10.4000/dms.1056.

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