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Journal articles on the topic 'Dithranol'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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1

&NA;. "Dithranol." Reactions Weekly &NA;, no. 772 (October 1999): 7. http://dx.doi.org/10.2165/00128415-199907720-00021.

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2

&NA;. "Dithranol." Reactions Weekly &NA;, no. 440 (February 1993): 8. http://dx.doi.org/10.2165/00128415-199304400-00030.

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3

Mahrle, Gustav. "Dithranol." Clinics in Dermatology 15, no. 5 (September 1997): 723–37. http://dx.doi.org/10.1016/s0738-081x(97)00019-9.

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4

&NA;. "Dithranol." Reactions Weekly &NA;, no. 400 (May 1992): 7. http://dx.doi.org/10.2165/00128415-199204000-00022.

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5

Chavali, Krishnadutt H., and Harish Dasari. "Dithranol." American Journal of Forensic Medicine and Pathology 33, no. 3 (September 2012): 253–55. http://dx.doi.org/10.1097/paf.0b013e3182198659.

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6

&NA;. "Dithranol." Reactions Weekly &NA;, no. 1388 (February 2012): 14. http://dx.doi.org/10.2165/00128415-201213880-00052.

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7

Melhorn, S. "Dithranol." Der Hautarzt 68, no. 5 (April 11, 2017): 421–23. http://dx.doi.org/10.1007/s00105-017-3977-5.

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8

C, Anahera, and Kahurangi S. "Development of Dithranol overloaded hard Lipid Nanoparticles." International Journal of Pharmacy and Biomedical Engineering 2, no. 3 (December 25, 2015): 5–8. http://dx.doi.org/10.14445/23942576/ijpbe-v2i3p102.

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Dithranol belongs to the keratolytic category, which is widely used drug in the treatment of psoriasis. The drug is virtually inexplicable in water. Many conservative quantity forms for psoriasis treatment have been have been formulated earlier, but they did not show good results. Hence in the present study, it was attempted to invent dithranol in the form of solid lipid nanoparticle. Solid lipid nanoparticles of dithranol were obtained by alteration of lipid spreading method. Preformulation studies were performed to check the compatibility of drug and excepient for the development of formulation by DSC and no statement was found. Solubility study, division coefficient purpose, UV examination, HPLC study, FTIR study were also performed. After the preformulation studies Dithranol loaded solid lipid nanoparticles was also prepared. Hence it was concluded that solid lipid nanoparticle of dithranol could be formulated.
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9

Prins, M., O. Q. J. Swinkels, J. M. Mommers, M. J. P. Gerritsen, and P. G. M. Valk. "Dithranol treatment of psoriasis in dithranol-sensitive patients." Contact Dermatitis 41, no. 2 (May 1, 2007): 116–17. http://dx.doi.org/10.1111/j.1600-0536.1999.tb06250.x.

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10

Legradi, Adam, Karolina Dulka, Gábor Jancsó, and Karoly Gulya. "Orofacial skin inflammation increases the number of macrophages in the maxillary subregion of the rat trigeminal ganglion in a corticosteroid-reversible manner." Cell and Tissue Research 382, no. 3 (July 21, 2020): 551–61. http://dx.doi.org/10.1007/s00441-020-03244-3.

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AbstractInflammation of the cutaneous orofacial tissue can lead to a prolonged alteration of neuronal and nonneuronal cellular functions in trigeminal nociceptive pathways. In this study, we investigated the effects of experimentally induced skin inflammation by dithranol (anthralin) on macrophage activation in the rat trigeminal ganglion. Tissue localization and protein expression levels of ionized calcium-binding adaptor molecule 1 (Iba1), a macrophage/microglia-specific marker, and proliferation/mitotic marker antigen identified by the monoclonal antibody Ki67 (Ki67), were quantitatively analyzed using immunohistochemistry and western blots in control, dithranol-treated, dithranol- and corticosteroid-treated, and corticosteroid-treated trigeminal ganglia. Chronic orofacial dithranol treatment elicited a strong pro-inflammatory effect in the ipsilateral trigeminal ganglion. Indeed, daily dithranol treatment of the orofacial skin for 3–5 days increased the number of macrophages and Iba1 protein expression in the maxillary subregion of the ipsilateral ganglion. In the affected ganglia, none of the Iba1-positive cells expressed Ki67. This absence of mitotically active cells suggested that the accumulation of macrophages in the ganglion was not the result of resident microglia proliferation but rather the extravasation of hematogenous monocytes from the periphery. Subsequently, when a 5-day-long anti-inflammatory corticosteroid therapy was employed on the previously dithranol-treated orofacial skin, Iba1 immunoreactivity was substantially reduced in the ipsilateral ganglion. Collectively, our findings indicate that both peripheral inflammation and subsequent anti-inflammatory therapy affect macrophage activity and thus interfere with the functioning of the affected sensory ganglion neurons.
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11

Estanqueiro, Marilene, Jaime Conceição, Maria Helena Amaral, and José Manuel Sousa Lobo. "Use of solid dispersions to increase stability of dithranol in topical formulations." Brazilian Journal of Pharmaceutical Sciences 50, no. 3 (September 2014): 583–90. http://dx.doi.org/10.1590/s1984-82502014000300018.

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The present study was planned to improve the stability of dithranol using solid dispersions (SD). Two different SD at a 1:9 ratio of dithranol/excipient were prepared: one of them using glyceryl behenate as excipient and the other using a mixture of argan oil with stearic acid (1:8 ratio) as excipient. Pure dithranol and SD of dithranol were incorporated in an oil-in-water cream and in a hydrophobic ointment in a drug/dermatological base ratio of 1:10. The physical and mechanical properties of semisolid formulations incorporating the pure drug and the developed SD were evaluated through rheological and textural analysis. To evaluate the stability, L*a*b* color space parameters of SD and semisolid formulations, and pH of hydrophilic formulations were determined at defined times, during one month. Each sample was stored at different conditions namely, light exposure (room temperature), high temperature exposition (37 °C) (protected from light) and protected from light (room temperature). Despite higher values of firmness and adhesiveness, hydrophobic ointment exhibited the best rheological features compared to the oil-in-water cream, namely a shear-thinning behavior and high thixotropy. These formulations have also presented more stability, with minor changes in L*a*b* color space parameters. The results of this study indicate that is possible to conclude that the developed SD contributed to the increased stability of dithranol.
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12

Thoma, Karl, and Christian Holzmann. "Photostability of dithranol." European Journal of Pharmaceutics and Biopharmaceutics 46, no. 2 (September 1998): 201–8. http://dx.doi.org/10.1016/s0939-6411(98)00024-1.

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13

Young, E. "Treatment of Psoriasis with Dithranol Cream Compared with Dithranol Paste." Dermatology 173, no. 6 (1986): 285–87. http://dx.doi.org/10.1159/000249272.

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14

Darr-Foit, S., S. Schliemann, P. Elsner, and S. Goetze. "Disseminierte kutane Sarkoidose mit nekrotisierenden Granulomen und erfolgreicher Dithranol-Therapie bei einem 75-jährigen Patienten." Aktuelle Dermatologie 46, no. 07 (July 2020): 319–21. http://dx.doi.org/10.1055/a-1154-4166.

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ZusammenfassungBei der Sarkoidose handelt es sich um eine inflammatorische Erkrankung unbekannter Ätiologie, die sich hauptsächlich in der Lunge und in den thorakalen Lymphknoten manifestiert, die aber eine Vielzahl weiterer Organsysteme betreffen kann. Die Sarkoidose der Haut kann dabei mit oder ohne einer systemischen Beteiligung einhergehen und sich mit variablem klinischen Bild präsentieren. Die charakteristischen histologischen Befunde sind nicht-verkäsende („nackte“) Granulome ohne oder mit nur wenigen Lymphozyten oder Plasmazellen. In seltenen Fällen kann auch eine zentrale Nekrose beobachtet werden wie bei tuberkuloiden Granulomen.Topische und/oder systemische Kortikosteroide gelten als Goldstandard für die Behandlung der kutanen Sarkoidose. Dithranol ist in erster Linie als topisches Antipsoriatikum bekannt. Nach unserem Wissen ist über die Verwendung von Dithranol bei kutaner Sarkoidose bisher nicht in der Literatur berichtet worden. Es könnte sich dabei um eine wirksame Therapiealternative zu topischen Kortikosteroiden handeln. Wir berichten über einen Patienten, der unter Dithranol-Monotherapie erfolgreich behandelt wurde.
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15

&NA;. "Dithranol + ultraviolet B light." Reactions Weekly &NA;, no. 353 (June 1991): 5. http://dx.doi.org/10.2165/00128415-199103530-00022.

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16

Tanzer, Helene, Matthias Seidel, and Wolfgang Wiegrebe. "Hydrophilic Derivatives of Dithranol." Archiv der Pharmazie 321, no. 8 (1988): 447–49. http://dx.doi.org/10.1002/ardp.19883210804.

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17

Haustein, Uwe-F., and Ingo Lohrisch. "Irritant Potential of Dithranol." Dermatology 173, no. 6 (1986): 288–93. http://dx.doi.org/10.1159/000249273.

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18

Sharpe, G., and P. M. Farr. "Short-contact dithranol therapy." British Journal of Dermatology 114, no. 4 (April 1986): 518–19. http://dx.doi.org/10.1111/j.1365-2133.1986.tb02865.x.

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19

Di Landro, Anna, Rossano Valsecchi, and Tullio Cainelli. "Contact allergy to dithranol." Contact Dermatitis 26, no. 1 (January 1992): 49–50. http://dx.doi.org/10.1111/j.1600-0536.1992.tb00869.x.

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20

Sehgal, Virendra N., Prashant Verma, and Ananta Khurana. "Anthralin/dithranol in dermatology." International Journal of Dermatology 53, no. 10 (September 10, 2014): e449-e460. http://dx.doi.org/10.1111/j.1365-4632.2012.05611.x.

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21

Whitefield, M. "Higher strength dithranol preparation." British Journal of Dermatology 117, no. 1 (July 1987): 134. http://dx.doi.org/10.1111/j.1365-2133.1987.tb04107.x.

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22

Müller, Klaus, Klaus K. Mayer, and Wolfgang Wiegrebe. "Dithranol and active oxygen species, II.1O2-oxidation of dithranol to Chrysazin." Archiv der Pharmazie 319, no. 11 (1986): 1009–18. http://dx.doi.org/10.1002/ardp.19863191109.

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23

Hollywood, Katherine A., Catherine L. Winder, Warwick B. Dunn, Yun Xu, David Broadhurst, Christopher E. M. Griffiths, and Royston Goodacre. "Exploring the mode of action of dithranol therapy for psoriasis: a metabolomic analysis using HaCaT cells." Molecular BioSystems 11, no. 8 (2015): 2198–209. http://dx.doi.org/10.1039/c4mb00739e.

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24

MUSTAKALLIO, K. "S135 Dithranol, still going strong." Journal of the European Academy of Dermatology and Venereology 9 (September 1997): S33. http://dx.doi.org/10.1016/s0926-9959(97)88968-4.

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25

Romaguera, C., F. Grimalt, and J. Vilaplana. "Acute Contact Dermatitis by Dithranol." Dermatitis 1, no. 3 (September 1990): 186–88. http://dx.doi.org/10.1097/01206501-199009000-00011.

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26

Romaguera, C., F. Grimalt, and J. Vilaplana. "Acute Contact Dermatitis by Dithranol." American Journal of Contact Dermatitis 1, no. 3 (September 1990): 186–88. http://dx.doi.org/10.1097/01634989-199009000-00011.

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27

Tanzer, Helene, Matthias Seidel, and Wolfgang Wiegrebe. "10-(ω-Carboxyacyl)-dithranol-Derivatives." Archiv der Pharmazie 322, no. 7 (1989): 441–44. http://dx.doi.org/10.1002/ardp.19893220712.

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28

Müller, Klaus, and Hans-Jürgen Duchstein. "Oxygenierung von Dithranol durch Übergangsmetallkomplexe." Archiv der Pharmazie 322, no. 1 (1989): 35–38. http://dx.doi.org/10.1002/ardp.19893220109.

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29

Burden, A. D., M. Stapleton, and M. H. Beck. "Dithranol allergy: fact or fiction?" Contact Dermatitis 27, no. 5 (May 1992): 291–93. http://dx.doi.org/10.1111/j.1600-0536.1992.tb03282.x.

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30

CHADHA, VISHAL, and SHRUTAKIRTHI D. SHENOI. "Allergic contact dermatitis from dithranol." Contact Dermatitis 41, no. 3 (September 1999): 166. http://dx.doi.org/10.1111/j.1600-0536.1999.tb06114.x.

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31

SEVILLE, R. H. "Simplified dithranol treatment for psoriasis*." British Journal of Dermatology 93, no. 2 (July 29, 2006): 205–8. http://dx.doi.org/10.1111/j.1365-2133.1975.tb06742.x.

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32

Müller, K., and H. Kappus. "Hydroxyl radical formation by dithranol." Biochemical Pharmacology 37, no. 22 (November 1988): 4277–80. http://dx.doi.org/10.1016/0006-2952(88)90607-7.

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33

REMITZ, ANITA, ARJA-LEENA KARINIEMI, EERO LEHTONEN, and STIG NORDLING. "Inhibition of proliferation of HeLa cells by dithranol (anthralin) and 10-butyryl dithranol (butantrone)." British Journal of Dermatology 120, no. 4 (April 1989): 525–31. http://dx.doi.org/10.1111/j.1365-2133.1989.tb01326.x.

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34

Haas, Norbert, Andrea Wulff-Woesten, Wolfram Sterry, and Hans Meffert. "Die Behandlung der Psoriasis capillitii mit Dithranol. Dithranol in the treatment of scalp psoriasis." Journal der Deutschen Dermatologischen Gesellschaft 1, no. 9 (September 2003): 688–93. http://dx.doi.org/10.1046/j.1610-0387.2003.03029.x.

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35

Viluksela, Matti, Kristiina Haasio, and Pekka T. Männistö. "Studies on the contact sensitizing activity of dithranol (anthralin) and 10-butyryl dithranol (butantrone)." Contact Dermatitis 23, no. 2 (August 1990): 103–10. http://dx.doi.org/10.1111/j.1600-0536.1990.tb03231.x.

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36

Huang, Hsu-Shan, Wolfgang Wiegrebe, and Klaus K. Mayer. "Electron-impact Induced and Thermal Decomposition of Dithranol Derivatives, II: Multiple H-Rearrangements in 10-Benzylthio-dithranol Radical Cations Elektronenstoß-induzierter und thermischer Zerfall von Dithranol Derivaten, 2. Mitt.: Mehrfache H-Umlagerungen in den Molekülionen des 10-Benzylthio-dithranols." Archiv der Pharmazie 327, no. 11 (1994): 735–38. http://dx.doi.org/10.1002/ardp.19943271110.

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37

Lowe, N. J. "Phototherapy and dithranol treatment of psoriasis." BMJ 294, no. 6575 (March 28, 1987): 839. http://dx.doi.org/10.1136/bmj.294.6575.839.

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38

Kemeny, L., M. Casato, and A. Dobozy. "Pharmacological studies on dithranol-induced dermatitis." Prostaglandins 35, no. 5 (May 1988): 834. http://dx.doi.org/10.1016/0090-6980(88)90231-6.

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39

Farkas, Á., L. Kemény, M. Gábor, and A. Dobozy. "Low-dose dithranol treatment and tape stripping induce tolerance to dithranol in mouse ear oedema model." Journal of Dermatological Science 16 (March 1998): S211. http://dx.doi.org/10.1016/s0923-1811(98)84261-8.

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40

Huang, Hsu-Shan, Klaus K. Mayer, and Wolfgang Wiegrebe. "Electron-impact Induced and Thermal Decomposition of Dithranol Derivatives, I: Thermolysis of 10-Phenylthio-dithranol in the Mass Spectrometer. Elektronenstoß-induzierter und thermischer Zerfall von Dithranol Derivaten, 1. Mitt.: Thermolyse von 10-Phenylthio-dithranol im Massenspektrometer." Archiv der Pharmazie 327, no. 10 (1994): 669–71. http://dx.doi.org/10.1002/ardp.19943271013.

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41

GRATTAN, C. E. H., A. P. CHRISTOPHER, M. ROBINSON, and M. A. COWAN. "Double-blind comparison of a dithranol and steroid mixture with a conventional dithranol regimen for chronic psoriasis." British Journal of Dermatology 119, no. 5 (November 1988): 623–26. http://dx.doi.org/10.1111/j.1365-2133.1988.tb03473.x.

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42

Müller, Klaus, Wolfgang Wiegrebe, and Maged Younes. "Formation of Active Oxygen Species by Dithranol, III Dithranol, Active Oxygen Species and Lipid Peroxidation in vivo." Archiv der Pharmazie 320, no. 1 (1987): 59–66. http://dx.doi.org/10.1002/ardp.19873200110.

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43

Keme'ny, L., A' Farkas, and A. Dobozy. "Low-dose dithranol treatment and tape stripping induce tolerance to dithranol in a mouse ear oedema model." British Journal of Dermatology 146, no. 5 (May 2002): 764–69. http://dx.doi.org/10.1046/j.1365-2133.2002.04663.x.

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44

Müller, Klaus, Ernst Eibler, Klaus K. Mayer, Wolfgang Wiegrebe, and Günter Klug. "Dithranol, Singlet Oxygen and Unsaturated Fatty Acids." Archiv der Pharmazie 319, no. 1 (1986): 2–9. http://dx.doi.org/10.1002/ardp.19863190103.

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45

Prins, M., Qoj Swinkels, B. Bertholet, and P. GM van der Valk. "Dithranol short-contact treatment of scalp psoriasis." Journal of Dermatological Treatment 10, no. 1 (January 1999): 13–17. http://dx.doi.org/10.3109/09546639909055905.

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46

Green, P. G., D. R. Forbes, and C. T. C. Kennedy. "The stability of dithranol in various bases." British Journal of Dermatology 113, s29 (July 1985): 26. http://dx.doi.org/10.1111/j.1365-2133.1985.tb12985.x.

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47

MORLIÉRE, P., L. DUBERTRET, T. SA E. MELO, C. SALET, M. FOSSE, and R. SANTUS. "The effect of anthralin (dithranol) on mitochondria." British Journal of Dermatology 112, no. 5 (July 29, 2006): 509–15. http://dx.doi.org/10.1111/j.1365-2133.1985.tb15258.x.

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48

Wiegrebe, W., E. Plumier, K. K. Mayer, U. Runne, W. Schultz-Amling, J. Rosmarinowski, g. J. Safar, and K. D. Kubka. "Experimental contribution to the dithranol-brown problem." Archives of Dermatological Research 277, no. 2 (January 1985): 153–55. http://dx.doi.org/10.1007/bf00414118.

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49

Wagner, Jobmann, Pönnighaus, and Kowalzick. "Klinische Erfahrungen mit einer kombinierten Calcipotriol/Dithranol/UVB-Therapie im Vergleich zur Dithranol/UVB-Therapie bei Psoriasis vulgaris." Aktuelle Dermatologie 27, no. 1 (January 2001): 21–24. http://dx.doi.org/10.1055/s-2001-10739.

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50

Hartman, M., M. Prins, O. Q. J. Swinkels, J. L. Severens, Th De Boo, G. J. Van Der Wilt, P. C. M. Van De Kerkhof, and P. G. M. Van Der Valk. "Cost-effectiveness analysis of a psoriasis care instruction programme with dithranol compared with UVB phototherapy and inpatient dithranol treatment." British Journal of Dermatology 147, no. 3 (September 2002): 538–44. http://dx.doi.org/10.1046/j.1365-2133.2002.04920.x.

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