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Journal articles on the topic 'Displacement amplification'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

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1

Luthra, Rajyalakshmi, and L. Jeffrey Medeiros. "Isothermal Multiple Displacement Amplification." Journal of Molecular Diagnostics 6, no. 3 (August 2004): 236–42. http://dx.doi.org/10.1016/s1525-1578(10)60516-8.

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2

Burd, S. C., R. Srinivas, J. J. Bollinger, A. C. Wilson, D. J. Wineland, D. Leibfried, D. H. Slichter, and D. T. C. Allcock. "Quantum amplification of mechanical oscillator motion." Science 364, no. 6446 (June 20, 2019): 1163–65. http://dx.doi.org/10.1126/science.aaw2884.

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Detection of the weakest forces in nature is aided by increasingly sensitive measurements of the motion of mechanical oscillators. However, the attainable knowledge of an oscillator’s motion is limited by quantum fluctuations that exist even if the oscillator is in its lowest possible energy state. We demonstrate a technique for amplifying coherent displacements of a mechanical oscillator with initial magnitudes well below these zero-point fluctuations. When applying two orthogonal squeezing interactions, one before and one after a small displacement, the displacement is amplified, ideally with no added quantum noise. We implemented this protocol with a trapped-ion mechanical oscillator and determined an increase by a factor of up to 7.3 (±0.3) in sensitivity to small displacements.

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3

Dean, F. B., S. Hosono, L. Fang, X. Wu, A. F. Faruqi, P. Bray-Ward, Z. Sun, et al. "Comprehensive human genome amplification using multiple displacement amplification." Proceedings of the National Academy of Sciences 99, no. 8 (April 16, 2002): 5261–66. http://dx.doi.org/10.1073/pnas.082089499.

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4

AROUETTE, Xavier, Yasuaki MATSUMOTO, Yoshiyuki OKAYAMA, and Norihisa MIKI. "2A1-G29 Hydraulic Amplification Mechanism for Large Displacement Actuators Systems." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2010 (2010): _2A1—G29_1—_2A1—G29_3. http://dx.doi.org/10.1299/jsmermd.2010._2a1-g29_1.

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5

Song, Jong-Keol, and JoséA Pincheira. "Spectral Displacement Demands of Stiffness- and Strength-Degrading Systems." Earthquake Spectra 16, no. 4 (November 2000): 817–51. http://dx.doi.org/10.1193/1.1586141.

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The effect of stiffness and strength degradation on the maximum inelastic displacement of single-degree-of-freedom (SDOF) systems was investigated. The SDOF model included strength and stiffness degradation with increasing deformation amplitude and upon reversal of loading cycles. Pinching of the hysteresis loops was also considered. Spectral displacements were calculated for oscillators with a myriad of degrading characteristics subjected to twelve ground motions on rock, firm and soft soils. The results show that the maximum displacements of degrading oscillators are, on average, larger than those of nondegrading systems. The displacement amplification varies significantly with the period, strength coefficient, degradation rate, and ground motion considered. Nonetheless, the amplification due to the degradation characteristics of the system is much more important in the short period range where average amplification factors of two or three are credible. The amplification factors proposed by ATC 33 provided conservative estimates for oscillators with periods greater than 0.3 seconds subjected to motions on rock or firm soil. On soft soils, a good correlation was found for periods greater than 1.5 seconds. At shorter periods, the ATC 33 factors underestimate the displacement amplification.

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6

Jiang, Z. "Genome amplification of single sperm using multiple displacement amplification." Nucleic Acids Research 33, no. 10 (June 2, 2005): e91-e91. http://dx.doi.org/10.1093/nar/gni089.

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7

Walker, G. Terrance, Melinda S. Fraiser, James L. Schram, Michael C. Little, James G. Nadeau, and Douglas P. Malinowski. "Strand displacement amplification—an isothermal,in vitroDNA amplification technique." Nucleic Acids Research 20, no. 7 (1992): 1691–96. http://dx.doi.org/10.1093/nar/20.7.1691.

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8

Fan, Wei, Huaxue Jin, Yuchen Fu, and Yuyang Lin. "A type of symmetrical differential lever displacement amplification mechanism." Mechanics & Industry 22 (2021): 5. http://dx.doi.org/10.1051/meca/2021003.

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The paper proposes a type of symmetrical flexure hinge displacement amplification mechanism, which is based on the differential lever to effectively improve the displacement output stroke of the PZT and reduce the additional displacement. In addition to describes the working principle of the differential displacement amplification, it establishes the semi-model of the micro-displacement amplification mechanism according to the symmetrical structure. The stiffness, displacement loss, and natural frequency of the amplification mechanism are simulated by finite element analysis (FEA). Simultaneously, build the mathematical model of amplification ratio to obtain the optimal driving frequency when the natural frequency is 930.58 Hz. The maximum output displacement of the designed mechanism is 313.05 µm and the amplification ratio is 6.50. Due to the symmetrical structure, the output additional displacement of the whole amplification mechanism is small.It provides a scientific basis for further improving the positioning accuracy of the micro/nano drive control system.

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9

Lasken, Roger S. "Genomic DNA amplification by the multiple displacement amplification (MDA) method." Biochemical Society Transactions 37, no. 2 (March 20, 2009): 450–53. http://dx.doi.org/10.1042/bst0370450.

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Large amounts of DNA are frequently required for use in detection assays and genomic analysis. The limited availability of DNA can be a critical obstacle to meeting research and clinical needs. DNA amplification methods are often required to generate sufficient material from small specimens or environmental samples with low DNA content. The MDA (multiple displacement amplification) reaction is increasingly the method of choice for many applications because of its extensive coverage of the genome, the generation of extremely long DNA products compared with older whole genome amplification methods and the high DNA yields, even from exceedingly low amounts of starting material. Remarkably, MDA enables genomic sequencing even from single microbial cells. Some of the uses of MDA and its strengths and limitations will be discussed.

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10

Walker, G. T. "Empirical aspects of strand displacement amplification." Genome Research 3, no. 1 (August 1, 1993): 1–6. http://dx.doi.org/10.1101/gr.3.1.1.

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11

Seckinger, D. "Strand displacement amplification and fluorescence polarization." Clinical Chemistry 42, no. 10 (October 1, 1996): 1720. http://dx.doi.org/10.1093/clinchem/42.10.1720.

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12

Li, Jinyin, Peng Yan, and Jianming Li. "Displacement amplification ratio modeling of bridge-type nano-positioners with input displacement loss." Mechanical Sciences 10, no. 1 (June 25, 2019): 299–307. http://dx.doi.org/10.5194/ms-10-299-2019.

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Abstract. This paper presents an improved modeling method for bridge-type mechanism by taking the input displacement loss into consideration, and establishes an amplification ratio model of bridge-type mechanism according to compliance matrix method and elastic beam theory. Moreover, the amplification ratio of the designed bridge-type nano-positioner is obtained by taking the guiding mechanism as the external load of bridge-type mechanism. Comparing with existing methods, the proposed model is more accurate, which is further verified by finite element analysis(FEA) and experimental test. The consistency of the results obtained from theoretical model, FEA and experimental testing indicates that the proposed model can accurately predict the amplification characteristics of nano-positioners, which helps the analysis and design of bridge-type nano-positioners in practical applications.

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13

Chen, Xiaodong, Zilong Deng, Siya Hu, Jinhai Gao, and Xingjun Gao. "Design of a Compliant Mechanism Based Four-Stage Amplification Piezoelectric-Driven Asymmetric Microgripper." Micromachines 11, no. 1 (December 24, 2019): 25. http://dx.doi.org/10.3390/mi11010025.

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The existing symmetrical microgrippers have larger output displacements compared with the asymmetrical counterparts. However, the two jaws of a symmetrical microgripper are less unlikely to offer the same forces on the two sides of a grasped micro-object due to the manufacture and assembly errors. Therefore, this paper proposes a new asymmetric microgripper to obtain stable output force of the gripper. Compared with symmetrical microgrippers, asymmetrical microgrippers usually have smaller output displacements. In order to increase the output displacement, a compliant mechanism with four stage amplification is employed to design the asymmetric microgripper. Consequently, the proposed asymmetrical microgripper possesses the advantages of both the stable output force of the gripper and large displacement amplification. To begin with, the mechanical model of the microgripper is established in this paper. The relationship between the driving force and the output displacement of the microgripper is then derived, followed by the static characteristics’ analysis of the microgripper. Furthermore, finite element analysis (FEA) of the microgripper is also performed, and the mechanical structure of the microgripper is optimized based on the FEA simulations. Lastly, experimental tests are carried out, with a 5.28% difference from the FEA results and an 8.8% difference from the theoretical results. The results from theoretical calculation, FEA simulations, and experimental tests verify that the displacement amplification ratio and the maximum gripping displacement of the microgripper are up to 31.6 and 632 μm, respectively.

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14

Ballantyne, Kaye N., Roland A. H. van Oorschot, and R. John Mitchell. "Increasing amplification success of forensic DNA samples using multiple displacement amplification." Forensic Science, Medicine, and Pathology 3, no. 3 (September 2007): 182–87. http://dx.doi.org/10.1007/s12024-007-0017-2.

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15

Yang, Xue Feng, Wei Li, and Yu Qiao Wang. "Analysis the Displacement Amplification of Compliant Parallel Four-Bar Using Piezo Actuator." Applied Mechanics and Materials 155-156 (February 2012): 201–5. http://dx.doi.org/10.4028/www.scientific.net/amm.155-156.201.

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This paper researched the displacement amplification and hysteresis of parallel four-bar amplification mechanism using piezo actuator. Firstly, the displacement amplification was analyzed by employing the material bending theory. Theory and finite element model (FEM) proved that the amplification ratio of parallel four-bar mechanism is only related to the position of driving point and the guiding beam displacement is linear with the driving point input when it is fixed. Then the Preisach model was employed to model the hysteresis of guiding beam and performed to control the output displacement of the mechanism. Experiments proved that the model can effectively improve the output displacement accurate of the guiding beam and can realize random sequence output displacement using the Preisach interpolation surface.

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16

Wang, Y., S. Nair, F. Nosten, and T. J. C. Anderson. "Multiple Displacement Amplification for Malaria Parasite DNA." Journal of Parasitology 95, no. 1 (February 2009): 253–55. http://dx.doi.org/10.1645/ge-1706.1.

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17

Morris, D. J., D. F. Bahr, and M. J. Anderson. "Displacement amplification in curved piezoelectric diaphragm transducers." Sensors and Actuators A: Physical 141, no. 2 (February 2008): 262–65. http://dx.doi.org/10.1016/j.sna.2007.09.013.

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18

Liu, Qing Ling. "Performance Analysis and Improved Design on the Compliant Micro-Displacement Amplification Mechanism." Applied Mechanics and Materials 346 (August 2013): 83–88. http://dx.doi.org/10.4028/www.scientific.net/amm.346.83.

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By analysing the structural characteristics of the compliant micro-displacement amplification mechanism and the examples of the compliant micro-displacement amplification mechanisms with different link length and link angel, the combined compliant structure formed with flexure hinges and link is important component, the length and the angel of the link affect the thickness ratio and length ratio of the combined compliant structure, which plays a key role in amplification of the mechanism. The design method is proposed aiming at improving the amplification, which is used in the improved design of the compliant micro-displacement amplification mechanism. The amplification analysis of the improved mechanism is done, which proves the validity and rationality of the improved design .

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19

Kloub, Hussam. "Force Amplification Mechanism for Increased Stroke and Speed Responses of Piezoelectric Stick-Slip Miniaturized Linear Motor." Proceedings 64, no. 1 (November 21, 2020): 17. http://dx.doi.org/10.3390/iecat2020-08518.

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In this paper, a mechanical system model based on Simulink software was developed for a proposed design for a stick-slip motor. Only the orientation of a cubic PZT element identifies the mode configuration of the motor. The preliminary results showed that force amplification mode exhibited roughly five times more speed, at one-hundred times more loading force, compared to the displacement amplification mode. Interestingly, when the output displacement was compared to maximum expansion of mechanical advantage mechanism, then the force amplification mode showed displacement amplification.

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20

Foster, Simon J., and Brendon J. Monahan. "Whole genome amplification from filamentous fungi using Phi29-mediated multiple displacement amplification." Fungal Genetics and Biology 42, no. 5 (May 2005): 367–75. http://dx.doi.org/10.1016/j.fgb.2005.01.013.

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21

Yang, Xue Feng, Wei Li, and Yu Fei Liu. "Displacement Amplification Analysis for Parallel Four-Bar Mechanism." Applied Mechanics and Materials 160 (March 2012): 229–33. http://dx.doi.org/10.4028/www.scientific.net/amm.160.229.

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The displacement amplification and hysteresis of parallel four-bar mechanism using piezo actuator were researched in this paper. The displacement amplification was analyzed by employing the material bending theory firstly. Theoretical and FEM analysis proved that the amplification ratio of parallel four-bar mechanism is only related to the position of driving point and the guiding arm displacement is directly proportional to the input with the certain structure. Then the Preisach model was employed to model the hysteresis of guiding arm and using the model to perform the research on the output displacement of the mechanism. Experiments proved that the analysis is correct and showed that this model can effectively improve the accurate of the guiding arm output displacement and can realize output arbitrary series displacement using the Preisach interpolation surface.

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22

Tu, Jing, Yi Qiao, Yuhan Luo, Naiyun Long, and Zuhong Lu. "Quantifying genome DNA during whole-genome amplification via quantitative real-time multiple displacement amplification." RSC Advances 11, no. 8 (2021): 4617–21. http://dx.doi.org/10.1039/d0ra09021b.

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23

Liu, Zhongxian, Jiaqiao Liu, Sibo Meng, and Xiaojian Sun. "Diffraction of elastic waves by a fluid-filled crack in a fluid-saturated poroelastic half-space." Geophysical Journal International 225, no. 3 (February 10, 2021): 1530–53. http://dx.doi.org/10.1093/gji/ggab043.

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SUMMARY An indirect boundary element method (IBEM) is developed to model the 2-D diffraction of seismic waves by a fluid-filled crack in a fluid-saturated poroelastic half-space, using Green's functions computed considering the distributed loads, flow and fluid characteristics. The influence of the fluid-filled crack on the diffraction characteristics is investigated by analysing key parameters, such as the excitation frequency, incident angle, crack width and depth, and medium porosity. The results for the fluid-filled crack model are compared to those for the fluid-free crack model under the same conditions. The numerical results demonstrate that the fluid-filled crack has a significant amplification effect on the surface displacements, and that the effect of the depth of the fluid-filled crack is more complex compared to the influence of other parameters. The resonance diffraction generates an amplification effect in the case of normally incident P waves. Furthermore, the horizontal and vertical displacement amplitudes reach 4.2 and 14.1, respectively. In the corresponding case of the fluid-free crack, the vertical displacement amplitude is only equal to 4.1, indicating the amplification effect of the fluid in the crack. Conversely, for normally incident SV waves at certain resonance frequencies, the displacement amplitudes above a fluid-filled crack may be lower than the displacement amplitudes observed in the corresponding case of a fluid-free crack.

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24

FURUKAWA, Eiichi, and Makoto MIZUNO. "Displacement amplification and reduction by means of linkage." Journal of the Japan Society for Precision Engineering 56, no. 10 (1990): 1823–28. http://dx.doi.org/10.2493/jjspe.56.1823.

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25

HUANG Wei-qing, 黄卫清, 史小庆 SHI Xiao-qing, and 王寅 WANG Yin. "Design of diamond piezoelectric micro displacement amplification mechanism." Optics and Precision Engineering 23, no. 3 (2015): 803–9. http://dx.doi.org/10.3788/ope.20152303.0803.

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26

Lasken, Roger S. "Single-cell genomic sequencing using Multiple Displacement Amplification." Current Opinion in Microbiology 10, no. 5 (October 2007): 510–16. http://dx.doi.org/10.1016/j.mib.2007.08.005.

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27

Motley, S., John M. Picuri, Chris D. Crowder, Jeremiah J. Minich, Steven A. Hofstadler, and Mark W. Eshoo. "Improved Multiple Displacement Amplification (iMDA) and Ultraclean Reagents." BMC Genomics 15, no. 1 (2014): 443. http://dx.doi.org/10.1186/1471-2164-15-443.

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28

Shi, Chao, Qi Liu, Cuiping Ma, and Wenwan Zhong. "Exponential Strand-Displacement Amplification for Detection of MicroRNAs." Analytical Chemistry 86, no. 1 (December 18, 2013): 336–39. http://dx.doi.org/10.1021/ac4038043.

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29

Spargo, C. A., M. S. Fraiser, M. Van Cleve, D. J. Wright, C. M. Nycz, P. A. Spears, and G. T. Walker. "Detection ofM. tuberculosisDNA using Thermophilic Strand Displacement Amplification." Molecular and Cellular Probes 10, no. 4 (August 1996): 247–56. http://dx.doi.org/10.1006/mcpr.1996.0034.

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30

Kuşy𝚤lmaz, Ahmet, and Cem Topkaya. "Displacement amplification factors for steel eccentrically braced frames." Earthquake Engineering & Structural Dynamics 44, no. 2 (July 14, 2014): 167–84. http://dx.doi.org/10.1002/eqe.2463.

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31

Gorrochotegui-Escalante, N., and W. C. Black IV. "Amplifying whole insect genomes with multiple displacement amplification." Insect Molecular Biology 12, no. 2 (April 2003): 195–200. http://dx.doi.org/10.1046/j.1365-2583.2003.00401.x.

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32

Yilmaz, Suzan, Martin Allgaier, and Philip Hugenholtz. "Multiple displacement amplification compromises quantitative analysis of metagenomes." Nature Methods 7, no. 12 (November 29, 2010): 943–44. http://dx.doi.org/10.1038/nmeth1210-943.

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33

Spits, Claudia, Cédric Le Caignec, Martine De Rycke, Lindsey Van Haute, André Van Steirteghem, Inge Liebaers, and Karen Sermon. "Whole-genome multiple displacement amplification from single cells." Nature Protocols 1, no. 4 (November 2006): 1965–70. http://dx.doi.org/10.1038/nprot.2006.326.

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34

Joneja, Aric, and Xiaohua Huang. "Linear nicking endonuclease-mediated strand-displacement DNA amplification." Analytical Biochemistry 414, no. 1 (July 2011): 58–69. http://dx.doi.org/10.1016/j.ab.2011.02.025.

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35

Yan, Jin, Jinong Feng, Seiyu Hosono, and Steve S. Sommer. "Assessment of multiple displacement amplification in molecular epidemiology." BioTechniques 37, no. 1 (July 2004): 136–43. http://dx.doi.org/10.2144/04371dd04.

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36

Huang, Mengting, Fang Yang, Jiye Fu, Pengfeng Xiao, Jing Tu, and Zuhong Lu. "Reaction parameter comparison and optimization of multiple displacement amplification." Analytical Methods 12, no. 1 (2020): 46–53. http://dx.doi.org/10.1039/c9ay01922g.

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After analysed MDA under different conditions, we found that different DNA denaturation methods before isothermal incubation can influence the amplification speed of MDA, and genome coverage uniformity was correlated with the amplification temperature.

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37

Zhou, Yunlei, Bingchen Li, Minghui Wang, Jun Wang, Huanshun Yin, and Shiyun Ai. "Fluorometric determination of microRNA based on strand displacement amplification and rolling circle amplification." Microchimica Acta 184, no. 11 (August 30, 2017): 4359–65. http://dx.doi.org/10.1007/s00604-017-2450-6.

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38

Ballantyne, Kaye N., Roland A. H. van Oorschot, Iman Muharam, Angela van Daal, and R. John Mitchell. "Decreasing amplification bias associated with multiple displacement amplification and short tandem repeat genotyping." Analytical Biochemistry 368, no. 2 (September 2007): 222–29. http://dx.doi.org/10.1016/j.ab.2007.05.017.

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39

Mullor Ruiz, Ismael, Jean-Michel Arbona, Amitkumar Lad, Oscar Mendoza, Jean-Pierre Aimé, and Juan Elezgaray. "Connecting localized DNA strand displacement reactions." Nanoscale 7, no. 30 (2015): 12970–78. http://dx.doi.org/10.1039/c5nr02434j.

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40

YE, Guo, Wei LI, Yuqiao WANG, Xuefeng YANG, and Ling YU. "Analysis on Displacement Amplification Ratio of a Flexible Bridge-Type Micro-Displacement Mechanism." ROBOT 33, no. 2 (August 3, 2011): 251–56. http://dx.doi.org/10.3724/sp.j.1218.2011.00251.

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41

Shen, Chuan Liang, Jing Shi Dong, and Feng Jun Tian. "The Analytical Modeling and Finite Element Analysis of a Bridge-Type Displacement Amplifier." Applied Mechanics and Materials 397-400 (September 2013): 652–55. http://dx.doi.org/10.4028/www.scientific.net/amm.397-400.652.

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The bridge-type displacement amplifier is modeled by the analytical method and finite element method. The analytical relationship between the input displacement and output displacement is established. The analytical model is validated by finite element method. The geometric parameters influence of amplification ratio is studied. The comparison results show that the link length and the link angle influence the amplification ratio dramatically. A small link angle and a large link length is beneficial to the amplification ratio. The finite element method has a more precise simulation results than the analytical method under the circumstance of small link angle and short link length.

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42

Giurgiutiu, V., C. A. Rogers, and Z. Chaudhry. "Design of Displacement-Amplified Induced-Strain Actuators for Maximum Energy Output." Journal of Mechanical Design 119, no. 4 (December 1, 1997): 511–17. http://dx.doi.org/10.1115/1.2826397.

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General stiffness concepts for effective use of induced strain principles as they apply to quasi-static actuation of structures and devices are presented. The conventional induced-strain actuator is first reviewed. The effect of structural elasticity is then discussed. Basic principles of displacement amplification are presented. The influences of structural and amplification elasticity are then discussed. An example of effective induced-strain actuator design with displacement amplification is provided.

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43

Lai, Wei, Mingshu Xiao, Haihong Yang, Li Li, Chunhai Fan, and Hao Pei. "Circularized blocker-displacement amplification for multiplex detection of rare DNA variants." Chemical Communications 56, no. 82 (2020): 12331–34. http://dx.doi.org/10.1039/d0cc05283c.

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44

Marine, Rachel, Coleen McCarren, Vansay Vorrasane, Dan Nasko, Erin Crowgey, Shawn W. Polson, and K. Wommack. "Caught in the middle with multiple displacement amplification: the myth of pooling for avoiding multiple displacement amplification bias in a metagenome." Microbiome 2, no. 1 (2014): 3. http://dx.doi.org/10.1186/2049-2618-2-3.

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45

Kumar, Sanjay, Shefali Raj Gangoliya, Mustapha Berri, Annie Rodolakis, and Syed Imteyaz Alam. "Whole genome amplification of the obligate intracellular pathogen Coxiella burnetii using multiple displacement amplification." Journal of Microbiological Methods 95, no. 3 (December 2013): 368–72. http://dx.doi.org/10.1016/j.mimet.2013.10.008.

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46

Raikar, S. V., C. Bryant, R. Braun, A. J. Conner, and M. C. Christey. "Whole genome amplification from plant cell colonies of somatic hybrids using strand displacement amplification." Plant Biotechnology Reports 1, no. 3 (July 12, 2007): 175–77. http://dx.doi.org/10.1007/s11816-007-0026-3.

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47

Muralidhara and Rathnamala Rao. "Displacement characteristics of a piezoactuator-based prototype microactuator with a hydraulic displacement amplification system." Journal of Mechanical Science and Technology 29, no. 11 (November 2015): 4817–22. http://dx.doi.org/10.1007/s12206-015-1028-7.

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48

Hellyer, Tobin J., and James G. Nadeau. "Strand displacement amplification: a versatile tool for molecular diagnostics." Expert Review of Molecular Diagnostics 4, no. 2 (March 2004): 251–61. http://dx.doi.org/10.1586/14737159.4.2.251.

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49

Li, Jixiang. "Complex Numerical Modelling of a Hydrostatic Displacement Amplification System." IFAC Proceedings Volumes 33, no. 26 (September 2000): 613–18. http://dx.doi.org/10.1016/s1474-6670(17)39213-3.

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50

Pan, Bo, Hongzhe Zhao, Chenxi Zhao, Puzhen Zhang, and Huajun Hu. "Nonlinear characteristics of compliant bridge-type displacement amplification mechanisms." Precision Engineering 60 (November 2019): 246–56. http://dx.doi.org/10.1016/j.precisioneng.2019.08.012.

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