Journal articles: 'Diseases Nutritional aspects'

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Berenji, Karolina, and Hajnalka Požar. "Nutritional aspects of neurological diseases." Medicinski casopis 53, no. 3 (2019): 101–11. http://dx.doi.org/10.5937/mckg53-21900.

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McCrory, Megan A., Nancy C. Wright, and David D. Kilmer. "Nutritional Aspects of Neuromuscular Diseases." Physical Medicine and Rehabilitation Clinics of North America 9, no. 1 (February 1998): 127–43. http://dx.doi.org/10.1016/s1047-9651(18)30283-3.

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Balestrieri, Paola, Mentore Ribolsi, Michele Pier Luca Guarino, Sara Emerenziani, Annamaria Altomare, and Michele Cicala. "Nutritional Aspects in Inflammatory Bowel Diseases." Nutrients 12, no. 2 (January 31, 2020): 372. http://dx.doi.org/10.3390/nu12020372.

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Crohn’s disease (CD) and ulcerative colitis (UC) are chronic, relapsing, inflammatory disorders of the digestive tract that characteristically develop in adolescence and early adulthood. The reported prevalence of malnutrition in inflammatory bowel disease (IBD) patients ranges between 20% and 85%. Several factors, including reduced oral food intake, malabsorption, chronic blood and proteins loss, and intestinal bacterial overgrowth, contribute to malnutrition in IBD patients. Poor nutritional status, as well as selective malnutrition or sarcopenia, is associated with poor clinical outcomes, response to therapy and, therefore, quality of life. The nutritional assessment should include a dietetic evaluation with the assessment of daily caloric intake and energy expenditure, radiological assessment, and measurement of functional capacity.

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Di Chio, Teresa, Christiane Sokollik, Diego G. Peroni, Lara Hart, Giacomo Simonetti, Franziska Righini-Grunder, and Osvaldo Borrelli. "Nutritional Aspects of Pediatric Gastrointestinal Diseases." Nutrients 13, no. 6 (June 19, 2021): 2109. http://dx.doi.org/10.3390/nu13062109.

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In the last decade, the role of nutritional management in pediatric gastrointestinal diseases has gained increasing popularity. Disease-specific diets have been introduced as conventional treatments by international guidelines. Patients tend to more willingly accept food-based therapies than drugs because of their relatively “harmless” nature. Apart from a diet’s therapeutic role, nutritional support is crucial in maintaining growth and improving clinical outcomes in pediatric patients. Despite the absence of classical “side effects”, however, it should be emphasized that any dietary modification might have negative consequences on children’s growth and development. Hence, expert supervision is always advised, in order to support adequate nutritional requirements. Unfortunately, the media provide an inaccurate perception of the role of diet for gastrointestinal diseases, leading to misconceptions by patients or their caregivers that tends to overestimate the beneficial role of diets and underestimate the potential adverse effects. Moreover, not only patients, but also healthcare professionals, have a number of misconceptions about the nutritional benefits of diet modification on gastrointestinal diseases. The aim of this review is to highlight the role of diet in pediatric gastrointestinal diseases, to detect misconceptions and to give a practical guide for physicians on the basis of current scientific evidence.

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Madeo, Frank, Sebastian J. Hofer, Tobias Pendl, Maria A. Bauer, Tobias Eisenberg, Didac Carmona-Gutierrez, and Guido Kroemer. "Nutritional Aspects of Spermidine." Annual Review of Nutrition 40, no. 1 (September 23, 2020): 135–59. http://dx.doi.org/10.1146/annurev-nutr-120419-015419.

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Natural polyamines (spermidine and spermine) are small, positively charged molecules that are ubiquitously found within organisms and cells. They exert numerous (intra)cellular functions and have been implicated to protect against several age-related diseases. Although polyamine levels decline in a complex age-dependent, tissue-, and cell type–specific manner, they are maintained in healthy nonagenarians and centenarians. Increased polyamine levels, including through enhanced dietary intake, have been consistently linked to improved health and reduced overall mortality. In preclinical models, dietary supplementation with spermidine prolongs life span and health span. In this review, we highlight salient aspects of nutritional polyamine intake and summarize the current knowledge of organismal and cellular uptake and distribution of dietary (and gastrointestinal) polyamines and their impact on human health. We further summarize clinical and epidemiological studies of dietary polyamines.

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Nerad, Judith L., and Sherwood L. Gorbach. "NUTRITIONAL ASPECTS OF HIV INFECTION." Infectious Disease Clinics of North America 8, no. 2 (June 1994): 499–515. http://dx.doi.org/10.1016/s0891-5520(20)30603-6.

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Crompton, D. W. T. "Nutritional aspects of infection." Transactions of the Royal Society of Tropical Medicine and Hygiene 80, no. 5 (January 1986): 697–705. http://dx.doi.org/10.1016/0035-9203(86)90368-8.

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Martínez-López, Erika, Edsaúl Emilio Pérez-Guerrero, Nora Magdalena Torres-Carrillo, Andres López-Quintero, Alejandra Betancourt-Núñez, and Itzae Adonai Gutiérrez-Hurtado. "Methodological Aspects in Randomized Clinical Trials of Nutritional Interventions." Nutrients 14, no. 12 (June 7, 2022): 2365. http://dx.doi.org/10.3390/nu14122365.

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Nutrition is an essential component when promoting human health. Without a doubt, improving the quality of one’s diet can improve one’s quality of life as a whole and help postpone the onset or control of many chronic diseases. The volume of publications in this field has increased in recent years, in line with increased awareness of the importance of nutrition in health; however, the quality of the evidence on which most nutritional guidelines are based remains low, due to errors in conducting nutritional interventions or because the information is primarily derived from observational studies. To enhance the evidence supporting clinical guidelines in nutrition, the quality of randomized clinical trials (RCT) based on nutritional interventions must be improved; nevertheless, due to their heterogeneous nature and a lack of specific guidelines for designing, performing, documenting, and reporting on this type of intervention, conducting a nutritional intervention is a real challenge. Following a review of the literature on the methodological and ethical standards, as well as four extensions of the CONSORT (Consolidated Standards of Reporting Trials) guidelines that should be considered when implementing a nutritional intervention, seven essential aspects were identified. The current narrative review includes definitions, examples, diagrams, and algorithms regarding aspects of the appropriate study design, the intervention of the control group, the randomization and blinding processes, the study population selection, as well as a description of the type of intervention and the personnel involved in carrying out the study in order to make the implementation of a nutritional intervention easier.

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Keith, Jeanette Newton. "Nutritional Aspects and Clinical Management of Chronic Disorders and Diseases." American Journal of Clinical Nutrition 79, no. 2 (February 1, 2004): 344–45. http://dx.doi.org/10.1093/ajcn/79.2.344a.

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Kordafshari, Gholamreza, Hoorieh Mohammadi Kenari, Mohammad Mehdi Esfahani, Mohammad Reza Shams Ardakani, Mansoor Keshavarz, Esmaeil Nazem, Maryam Moghimi, and Arman Zargaran. "Nutritional Aspects to Prevent Heart Diseases in Traditional Persian Medicine." Journal of Evidence-Based Complementary & Alternative Medicine 20, no. 1 (October 19, 2014): 57–64. http://dx.doi.org/10.1177/2156587214553939.

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Cardiovascular diseases are major health complications currently in various societies. Management of heart diseases as a prevention step or as treatment with low-cost procedures like lifestyle modifications including nutrition are important current trends. Although the term nutrition dates back to 2 past centuries, Persian physicians contributed to this term at least from 1000 years ago. Rhazes (865-925 AD) was one of the pioneers in this field. He preferred using foods in treating illnesses. “Foods and drinks” were 1 subject from 6 principles ( Setteh Zarorieh) that Persian physicians believed can affect human health. In this review, we described some medieval Persian views on the role of nutrition in heart diseases and compare their prescriptions with current findings. Interestingly, current investigations mostly support Persian medicine principles. Historically, this work shows that the concept of nutrition in heart diseases has had a successful background at least from 1000 years ago in Persia.

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Santos, Gilton Marques dos, Luciana Rodrigues Silva, and Genoile Oliveira Santana. "Nutritional impact of inflammatory bowel diseases on children and adolescents." Revista Paulista de Pediatria 32, no. 4 (December 2014): 403–11. http://dx.doi.org/10.1590/s0103-05822014000400018.

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OBJECTIVE: To perform a sistematiy review of the literature about the nutritional impact of inflammatory bowel diseases in children and adolescents.DATA SOURCES: A systematic review was performed using PubMed/MEDLINE, LILACS and SciELO databases, with inclusion of articles in Portuguese and in English with original data, that analyzed nutritional aspects of inflammatory bowel diseases in children and adolescents. The initial search used the terms "inflammatory bowel diseases" and "children" or "adolescents" and "nutritional evaluation" or "nutrition deficiency". The selection of studies was initially performed by reading the titles and abstracts. Review studies and those withouth data for pediatric patients were excluded. Subsequently, the full reading of the articles considered relevant was performed.RESULTS: 237 studies were identified, and 12 of them were selected according to the inclusion criteria. None of them was performed in South America. During the analysis of the studies, it was observed that nutritional characteristics of patients with inflammatory bowel disease may be altered; the main reports were related to malnutrition, growth stunting, delayed puberty and vitamin D deficiency.CONCLUSION: There are nutritional consequences of inflammatory bowel diseases in children and adolescents, mainly growth stunting, slower pubertal development, underweight and vitamin deficiencies. Nutritional impairments were more significant in patients with Crohn's disease; overweight and obesity were more common in patients with ulcerative rectocolitis. A detailed nutritional assessment should be performed periodically in children and adolescents with inflammatory bowel disease.

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Avdić, Dijana, Amila Jaganjac, Arzija Pašalić, Fatima Jusupović, and Amila Kapetanović. "Clinical aspects and importance of nutrition in homeostasis of the bone tissue." Journal of Health Sciences 6, no. 2 (October 18, 2016): 87–93. http://dx.doi.org/10.17532/jhsci.2016.380.

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Substantial changes have occurred in the nutritional management of many diseases in the last twenty years. Introduction of standards, clinical review and implementation of evidence based practice led to re-evaluation of some established dietary interventions. The most common form of osteoporosis is the primary osteoporosis, which is the result of the bone loss and deterioration of bone structure, as people age. Bone loss and osteoporosis can be prevented through adequate nutrition, physical activity, and, if necessary, appropriate treatment. This review will focus on nutritional and clinical aspects of bone tissue homeostasis, with references to physiological and pathophysiological processes.

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Nenartovich, I., and A. Pochkailo. "Nutrition for prevention and treatment of inflammatory bowel diseases in pediatric patients." Immunopathology, Allergology, Infectology 2021, no. 2 (April 1, 2021): 40–48. http://dx.doi.org/10.14427/jipai.2021.2.40.

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The genetic component and epigenetics are considered important in the pathogenesis of inflammatory bowel diseases today. Nutrition is being actively studied among epigenetic factors. This article presents a critical analysis of published data on the nutritional aspects of prevention and treatment of inflammatory bowel diseases in children. The data on the effectiveness of specific diets are summarized, nutrition schemes are given during the period of exacerbation, aiming for the induction of remission and for its maintenance.

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Curtis, Ashley R. "Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional, and Deposition Diseases." American Journal of Dermatopathology 33, no. 2 (April 2011): 203. http://dx.doi.org/10.1097/dad.0b013e31820e34f0.

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Burgdorf, Walter. "Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Diseases." Journal of Cutaneous Pathology 38, no. 9 (April 26, 2011): 759. http://dx.doi.org/10.1111/j.1600-0560.2011.01707.x.

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Cherian, G. "Symposium: Metabolic and Cardiovascular Diseases in Poultry: Nutritional and Physiological Aspects." Poultry Science 86, no. 5 (May 2007): 983. http://dx.doi.org/10.1093/ps/86.5.983.

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Pompeu, M. A., V. M. Barbosa, N. R. S. Martins, N. C. Baião, L. J. C. Lara, J. S. R. Rocha, and D. J. A. Miranda. "Nutritional aspects related to non-infectious diseases in locomotor system of broilers." World's Poultry Science Journal 68, no. 4 (December 1, 2012): 669–78. http://dx.doi.org/10.1017/s0043933912000803.

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Pandey, Chandra M. "Statistical Aspects of Community Health and Nutrition." Indian Journal of Community Health 32, no. 2 (June 30, 2020): 468. http://dx.doi.org/10.47203/ijch.2020.v32i02.032.

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One of the most common problems with the area of health and nutritional research is the limited number of quality books available that can provide research methodology, health indicators and their trend in a single volume. Statistical Aspects of Community Health and Nutrition is a one of the problem-based text book which completely fulfils the gap and stands to our expectations. This book is a single but comprehensive resource on maternal and infant mortality, anemia especially in adolescents and women in reproductive age group and, their causes, prevention, evaluation and validation methods including 30 clusters design, logistic regression and findings of recent relevant studies. Despite above, author also discusses the food insecurity and hunger, tuberculosis, influenza like prevalent diseases, their hotspot and available estimates, techniques for analyzing multiple response data, and small area estimation.

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Esposito, Pasquale, Giacomo Garibotto, Daniela Picciotto, Francesca Costigliolo, Francesca Viazzi, and Novella Evelina Conti. "Nutritional Challenges in Pregnant Women with Renal Diseases: Relevance to Fetal Outcomes." Nutrients 12, no. 3 (March 24, 2020): 873. http://dx.doi.org/10.3390/nu12030873.

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Pregnancy in women affected by chronic kidney disease (CKD) has become more common in recent years, probably as a consequence of increased CKD prevalence and improvements in the care provided to these patients. Management of this condition requires careful attention since many clinical aspects have to be taken into consideration, including the reciprocal influence of the renal disease and pregnancy, the need for adjustment of the medical treatments and the high risk of maternal and obstetric complications. Nutrition assessment and management is a crucial step in this process, since nutritional status may affect both maternal and fetal health, with potential effects also on the future development of adult diseases in the offspring. Nevertheless, few data are available on the nutritional management of pregnant women with CKD and the main clinical indications are based on small case series or are extrapolated from the general recommendations for non-pregnant CKD patients. In this review, we discuss the main issues regarding the nutritional management of pregnant women with renal diseases, including CKD patients on conservative treatment, patients on dialysis and kidney transplant patients, focusing on their relevance on fetal outcomes and considering the peculiarities of this population and the approaches that could be implemented into clinical practice.

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Tazuma, Susumu, Keishi Kanno, Akiko Sugiyama, and Nobusuke Kishikawa. "Nutritional factors (nutritional aspects) in biliary disorders: Bile acid and lipid metabolism in gallstone diseases and pancreaticobiliary maljunction." Journal of Gastroenterology and Hepatology 28 (November 19, 2013): 103–7. http://dx.doi.org/10.1111/jgh.12241.

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Stawny, M., R. Olijarczyk, E. Jaroszkiewicz, and A. Jelińska. "Pharmaceutical Point of View on Parenteral Nutrition." Scientific World Journal 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/415310.

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Parenteral nutrition—a form of administering nutrients, electrolytes, trace elements, vitamins, and water—is a widely used mode of therapy applied in many diseases, in patients of different ages both at home and in hospital. The success of nutritional therapy depends chiefly on proper determination of the patient’s energetic and electrolytic needs as well as preparation and administration of a safe nutritional mixture. As a parenterally administered drug, it is expected to be microbiologically and physicochemically stable, with all of the components compatible with each other. It is very difficult to obtain a stable nutritional mixture due to the fact that it is a complex, two-phase drug. Also, the risk of incompatibility between mixture components and packaging should be taken into consideration and possibly eliminated. Since parenteral nutrition is a part of therapy, simultaneous use of drugs may cause pharmacokinetic and pharmacodynamic interactions as well as those with the pharmaceutical phase. The aim of this paper is to discuss such aspects of parenteral nutrition as mixture stability, methodology, and methods for determining the stability of nutritional mixtures and drugs added to them.

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Jain, Kapila, and Vibha Bhatnagar. "Impact of Dietary Module on Nutritional Knowledge and Consumption Pattern of Type 2 Diabetic Patients at Risk of Cardiac Diseases." Indian Journal of Nutrition and Dietetics 53, no. 4 (December 1, 2016): 433. http://dx.doi.org/10.21048/ijnd.2016.53.4.8401.

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As diabetes is a disease which continues for a lifetime, the proper therapy methods should be applied in order to control the disease, remove or relief the symptoms, prevent and delay the complications. Patients have a major role in the control and treatment of T2DM. So knowledge of different aspects of this disease especially diet therapy is very important for these patients. The aim of the study was to determine the effect of nutrition education on diabetic patient's nutritional knowledge and food consumption habits. To provide nutrition education, an evaluated dietary module with the help of 16 panel members was developed. Further in this study, diabetic subjects were divided into two groups, experimental (50 subjects) and control (50 subjects). Nutrition education with the help of module was provided to the experimental group and not to the control group. In order to determine the nutritional knowledge, 30 questions related to general facts and management information about disease were presented to the patients. "24 hour recall method" for three consecutive days was used to determine the food intake. Further daily intake of energy and other nutrients were determined using computer software. At the end of nutrition education, significant differences were detected in experimental group regarding nutritional knowledge, dietary and nutrient intake and a higher percentage change was also observed in experimental group as compared to control group. The efficacy of the dietary module in improving nutritional knowledge, dietary intake was confirmed in the present study because obtained results indicated that education was effective in changing their consumption habits.

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Fanny, Lydia, Megawati Megawati, and Fatmawaty Suaib. "DAYA TERIMA KUE DONAT DAN PUKIS SUBSTITUSI TEPUNG UBI JALAR UNGU DAN TEPUNG KACANG HIJAU." Media Gizi Pangan 26, no. 1 (July 10, 2019): 78. http://dx.doi.org/10.32382/mgp.v26i1.1008.

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ABSTRACTOne of the problems which nutrition is still main in toddlers nutrition that is the problem a chronicle or called also stunting. Children suffer stunting due to lack of food intake and its diseases repeated especially of infection diseases which can increase metabolic needs and reduce appetite that has happened that abnormality in bodily form short although the genes into cells show the potential to grow. One way to solve the problem is stunting with consuming foods high in protein, local this research aims to review the receipt and macro nutrient analysis on the cake donuts and pukis with the substitution of flour sweet potato flour. purple and green beans. Resources i judged based on the panel against 30. hedonicThe results of the best nutritional value received analyzed the protein can use a method of micro kjedahl, fat soxhlet, analysis method and its luff schroll. carbohydrates analysis method. The research results show that the panel power received our foremost is f2 ( pukis ). Based on the aspect of the color of the most favored f2 ( pukis ) 73.3 %, as many as the aspect of the scent of f1 ( doughnuts ) 90 %, as many as the aspect of texture f2 ( pukis ) as much as 86.7 % and aspects of the f2 ( pukis ) 90 %. Nutritional content protein f1 ( doughnuts ) 8.43 %, as much as fat f1 ( doughnuts ) as much as 17.37 % and carbohydrates f1 ( doughnuts ) as much as 51.02 % while for nutritional content protein f2 ( pukis ) 7.37 %, as much as fat f2 ( pukis ) as much as 4.25 % and carbohydrates f2 ( pukis ) as much as 49.16 %. Keywords : Doughnut , green beans , pukis, sweet potato purple

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Caimi, G., C. Carollo, and R. Lo Presti. "Pathophysiological and clinical aspects of malnutrition in chronic renal failure." Nutrition Research Reviews 18, no. 1 (June 2005): 89–97. http://dx.doi.org/10.1079/nrr200599.

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AbstractKidney diseases are the ninth leading cause of death in the USA. In these patients cardiovascular mortality is greater than in the general population. This observation, not completely explained by the so-called ‘traditional’ cardiovascular risk factors, lead the authors to postulate other ‘emerging’ ones found in chronic renal failure patients. Among these new findings, nutritional status, considered as the balance existing between nutrient requirements and intakes, plays an important role for the development of cardiovascular diseases. In fact several nutritional parameters are widely known as pathophysiological determinants of cardiovascular disturbances, which are based on accelerated atherosclerosis, due especially to enhanced oxidative stress and endothelial dysfunction. Chronic renal failure is a clinical condition that from many points of view seems to be a chronic inflammatory state, and many studies confirm this observation. This influences nutritional status especially in dialysis patients. Malnutrition is related in turn to accelerated atherosclerosis thus leading to a postulated ‘malnutrition, inflammation, atherosclerosis’ (MIA) syndrome in which malnutrition, inflammation and atherosclerosis contribute to an elevated cardiovascular mortality rate. The present review explores this issue, first by describing epidemiological aspects of malnutrition in chronic renal failure patients and then by analysing the specific biochemical and metabolic features of these patients.

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Fabozzi, Gemma, Giulia Verdone, Mariachiara Allori, Danilo Cimadomo, Carla Tatone, Liborio Stuppia, Marica Franzago, et al. "Personalized Nutrition in the Management of Female Infertility: New Insights on Chronic Low-Grade Inflammation." Nutrients 14, no. 9 (May 3, 2022): 1918. http://dx.doi.org/10.3390/nu14091918.

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Increasing evidence on the significance of nutrition in reproduction is emerging from both animal and human studies, suggesting a mutual association between nutrition and female fertility. Different “fertile” dietary patterns have been studied; however, in humans, conflicting results or weak correlations are often reported, probably because of the individual variations in genome, proteome, metabolome, and microbiome and the extent of exposure to different environmental conditions. In this scenario, “precision nutrition”, namely personalized dietary patterns based on deep phenotyping and on metabolomics, microbiome, and nutrigenetics of each case, might be more efficient for infertile patients than applying a generic nutritional approach. In this review, we report on new insights into the nutritional management of infertile patients, discussing the main nutrigenetic, nutrigenomic, and microbiomic aspects that should be investigated to achieve effective personalized nutritional interventions. Specifically, we will focus on the management of low-grade chronic inflammation, which is associated with several infertility-related diseases.

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González Gross, Marcela. "Research challenges on the interaction between exercise and nutrition." Anales de la Real Academia Nacional de Farmacia 87, no. 87(04) (2021): 395–402. http://dx.doi.org/10.53519/analesranf.2021.87.04.03.

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The increase in life expectancy and non-communicable chronic diseases (obesity, type 2 diabetes, cardiovascular diseases, cancer, dementia, depression, among other) have led to both Sports and Nutrition Sciences gaining importance in research and in Public Health. But the lack of connection and collaboration between these areas has caused most scientific studies to analyze these aspects separately. The current state of scientific knowledge seems to indicate that it is reasonable to address them jointly, although new questions clearly arise in the combination of both. The combined effect between nutrients and physiological stimuli of training loads are not the same in all people, since there is an individualized response motivated by genetic and epigenetic aspects. Therefore, we must be able to identify responders and non-responders to nutritional and exercise interventions. Among the many challenges that arise today, we find the complexity of the energy balance, for many years misunderstood as a mathematical equation; the effect that physical activity or its absence has on habits and nutritional status; sarcopenia and osteoporosis; sarcopenic obesity; microbiota; cognitive impairment; and mortality.

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Macit, Melahat S., and Nilüfer Acar-Tek. "Current Perspectives for Diabetes and Allostatic Load: The Role of Nutrition." Current Nutrition & Food Science 15, no. 7 (November 12, 2019): 646–52. http://dx.doi.org/10.2174/1573401314666180620164859.

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Allostasis and allostatic load are new concepts explaining the changes in body stemming from chronic stress. These concepts are explained with the assessment of metabolic, cardiovascular, inflammatory, and neuroendocrine systems. Type 2 Diabetes Mellitus (DM) is a chronic disease with the fluctuations in fasting plasma glucose, and also in other various biomarkers and poses a risk forother chronic diseases. The course and duration of the disease, genetic factors, and environmental factors, including nutrition, aggravate these complications. Allostatic load is a multi-system assessment. Individuals’ compliance with the medical nutrition therapy in the short and long-term, changes in anthropometric and biochemical biomarkers that are used to measure the nutritional status. In the monitoring of patients with diabetes, it’s important to assess metabolic, cardiovascular, neuroendocrine, and immune system biomarkers as well as fasting blood glucose. There exist studies in the literature, investigating the relationship of the allostatic load with socio-economic status, chronic diseases such as diabetes and cardiovascular diseases, gender, and ethnicity. In these studies, chronic stress, nutritional status, stress, and allostasis are briefly described. In the present literature review, it was aimed to evaluate different aspects of the relationships among diabetes, nutrition, allostatic load, and stress.

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Barone, Michele, Maria Viggiani, Maria Anelli, Rosalinda Fanizzi, Orsola Lorusso, Giuseppe Lopalco, Luca Cantarini, Alfredo Di Leo, Giovanni Lapadula, and Florenzo Iannone. "Sarcopenia in Patients with Rheumatic Diseases: Prevalence and Associated Risk Factors." Journal of Clinical Medicine 7, no. 12 (December 1, 2018): 504. http://dx.doi.org/10.3390/jcm7120504.

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The prevalence of sarcopenia in rheumatic diseases has been evaluated in single diseases using various diagnostic approaches, generating conflicting data on the pathogenetic mechanism(s). Herein, we evaluated both muscle mass index (MMI) and muscle strength to assess sarcopenia and presarcopenia in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). Moreover, we evaluated the possible impact of disease/patient-related characteristics, therapeutic regimens, and nutritional aspects on sarcopenia. The present study included 168 patients of both genders, aged 40–75 years. All patients underwent a nutritional evaluation, physical activity level assessment, rheumatologic evaluation, and an MMI and muscle strength assessment. The prevalence of sarcopenia was about 20% in all the three rheumatologic diseases, whereas presarcopenia was significantly different in RA, PsA and AS (p = 0.006). At multivariate analysis, only age ≥60 years and the presence of a disability were associated with a significantly increased risk of sarcopenia (p = 0.006 and p = 0.01, respectively), while a higher C-reactive protein did not reach statistical significance. Sarcopenia is similar in RA, PsA and AS, whereas presarcopenia significantly differs in these three diseases. Disease activity/inflammation and nutritional aspects do not influence sarcopenia, while age ≥60 years and the presence of a disability significantly increase the risk of sarcopenia.

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Kumar, Krishan. "Nutraceutical Potential and Processing Aspects of Oyster Mushrooms (PleurotusSpecies)." Current Nutrition & Food Science 16, no. 1 (January 13, 2020): 3–14. http://dx.doi.org/10.2174/1573401314666181015111724.

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Background:Oyster mushrooms (Pleurotus species) have gained considerable attention of food technologist and nutritionist for their nutraceutical properties. Oyster mushrooms are considered as functional foods due to their richness in functional food ingredients. In recent times, consumption of these mushrooms has increased considerably due to their numerous health benefits. These are potential sources of bioactive components, which are sufficient enough for prevention and treatment of various lifestyle diseases. There are about 200 different species in the genus Pleurotus and these are commonly referred to as “oyster mushrooms”.Objective:The study aimed to grasp a collective information on nutraceutical and processing aspects of highly perishable but nutritious oyster mushroomResults:Pleurotus ostreatus is the most commonly consumed species all over the world due to its superior flavor, taste and nutraceutical properties. It acts as a source of natural antioxidants which might be beneficial for human health in preventing or reducing oxidative damage. Nutritionally, these species are rich sources of proteins, dietary fibres, β-glucan, vitamin B-complex, vitamin C and minerals. They contain higher proportions of certain amino acids such as methionine, cystine and aspartic acid than other edible mushrooms. Oyster mushrooms have been reported to possess hypocholesterolemic, anti-bacterial, anti-diabetic, anti-oxidant, anti-arthritic, anti-carcinogenic, hepatoprotective, anti-viral activities and act as natural resources of immunotherapy activities. The use of these mushrooms can overcome the deficiency of protein in the developing countries where there is unavailability or unacceptability of good quality proteins from animal sources because of religious restrictions.Conclusion:Because of the occurrence of abundant nutritional ingredients and other bioactive components in P. ostreatus, they have a great scope as a potential source for the development of functional or specialty foods for value addition of deficient foods so as to alleviate the nutritional deficiency diseases from society.

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Marteau, P., and M. C. Boutron-Ruault. "Nutritional advantages of probiotics and prebiotics." British Journal of Nutrition 87, S2 (May 2002): S153—S157. http://dx.doi.org/10.1079/bjn2002531.

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The potential ‘nutritional advantages’ of probiotics and prebiotics consist of preventive, and sometimes curative, effects against certain diseases. The evidence supporting such advantages, which requires randomised controlled trials and consistency of results from study to study, is rapidly increasing. This article summarizes the effects against diseases of intestinal origin. There is a high level of evidence for positive effects of some prebiotics to alleviate constipation and treat hepatic encephalopathy. Interesting aspects, but with a lower level of evidence at the present time, include prevention of colon cancer, intestinal infection, and recurrence of inflammatory bowel disease. There is a high level of evidence for positive effects of some probiotics in the alleviation of lactose intolerance, antibiotic-associated intestinal disorders and gastroenteritis. Evidence is rapidly growing regarding the prevention of recurrence of inflammatory bowel diseases. Positive trials have suggested preventive effects against intestinal colonization with specific gut pathogens includingClostridium difficileandHelicobacter pylori.

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Chakniramol, Sukwasa, Andreas Wierschem, Man-Gi Cho, and Khawaja Muhammad Imran Bashir. "Physiological and Clinical Aspects of Bioactive Peptides from Marine Animals." Antioxidants 11, no. 5 (May 22, 2022): 1021. http://dx.doi.org/10.3390/antiox11051021.

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Biological molecules in nutraceuticals and functional foods have proven physiological properties to treat human chronic diseases. These molecules contribute to applications in the food and pharmaceutical industries by preventing food spoilage and cellular injury. Technological advancement in the screening and characterization of bioactive peptides has enabled scientists to understand the associated molecules. Consistent collaboration among nutritionists, pharmacists, food scientists, and bioengineers to find new bioactive compounds with higher therapeutic potential against nutrition-related diseases highlights the potential of the bioactive peptides for food and pharmaceutic industries. Among the popular dietary supplements, marine animals have always been considered imperative due to their rich nutritional values and byproduct use in the food and pharmaceutical industries. The bioactive peptides isolated from marine animals are well-known for their higher bioactivities against human diseases. The physiological properties of fish-based hydrolyzed proteins and peptides have been claimed through in vitro, in vivo, and clinical trials. However, systematic study on the physiological and clinical significance of these bioactive peptides is scarce. In this review, we not only discuss the physiological and clinical significance of antioxidant and anticancer peptides derived from marine animals, but we also compare their biological activities through existing in vitro and in vivo studies.

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Bhattacharya, Preeti Tomar, Satya Ranjan Misra, and Mohsina Hussain. "Nutritional Aspects of Essential Trace Elements in Oral Health and Disease: An Extensive Review." Scientifica 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/5464373.

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Human body requires certain essential elements in small quantities and their absence or excess may result in severe malfunctioning of the body and even death in extreme cases because these essential trace elements directly influence the metabolic and physiologic processes of the organism. Rapid urbanization and economic development have resulted in drastic changes in diets with developing preference towards refined diet and nutritionally deprived junk food. Poor nutrition can lead to reduced immunity, augmented vulnerability to various oral and systemic diseases, impaired physical and mental growth, and reduced efficiency. Diet and nutrition affect oral health in a variety of ways with influence on craniofacial development and growth and maintenance of dental and oral soft tissues. Oral potentially malignant disorders (OPMD) are treated with antioxidants containing essential trace elements like selenium but even increased dietary intake of trace elements like copper could lead to oral submucous fibrosis. The deficiency or excess of other trace elements like iodine, iron, zinc, and so forth has a profound effect on the body and such conditions are often diagnosed through their early oral manifestations. This review appraises the biological functions of significant trace elements and their role in preservation of oral health and progression of various oral diseases.

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Salikova, S. P., V. B. Grinevich, and A. A. Vlasov. "The Modern Aspects of Nutrition during Chronic Heart Failure." Experimental and Clinical Gastroenterology, no. 12 (January 15, 2022): 62–73. http://dx.doi.org/10.31146/1682-8658-ecg-196-12-62-73.

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Nutrition occupies one of the important places in the programs of prevention and non-drug therapy of CHF and associated diseases. At the same time, the validity of dietary recommendations to patients regarding salt intake, dietary habits and the use of individual nutraceuticals is questionable. The purpose of this review is to present up-to-date data of clinical and experimental studies concerning sodium restriction, the use of various diets, nutraceuticals, and means for correcting intestinal dysbiosis in CHF. Materials and methods: the articles are searched in the databases eLibraryRU and Medline by key terms and their combinations: “heart failure”, “diet”, “sodium restriction”, “nutraceuticals”, “nutrition”, “cardiac cachexia”, “nutritional support”, “salt”, “dietary supplement”, “probiotic”, “prebiotic”, “enteral nutrition” in Russian and English. We select articles containing the results of clinical and experimental studies published from 1997 to 2021. The research data indicate that the pathogenesis of anorexia, malnutrition and “metabolic remodeling” of the myocardium in CHF is based on complex mechanisms determined by stagnant phenomena in the liver, impaired permeability of the edematous intestinal wall, dysbiosis and chronic systemic infl ammation. The recommendations on the consumption of sodium from 2 to 2.5 g/day and table salt from 5 to 6 g/day in patients with CHF are justified. Limitation of fluid intake is relevant only for decompensation of CHF. The use of the Mediterranean and antihypertensive (DASH) diets is recognized by most authors as a promising direction for the prevention and treatment of CHF. The enrichment of the diet of patients with CHF with ω-3 polyunsaturated fatty acids, coenzyme Q10, dietary fibers, polyphenols and saponins is justified. The benefits of enteral nutrition and the complex use of nutraceuticals in order to slow the progression of weight loss, reduce the severity of neurohormonal and pro-inflammatory shifts are shown. Promising trends of research are the creation of personalized diets taking into account the peculiarities of the course of CHF, the nutritional status, the composition of the intestinal microbiota and its metabolites.

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Verma, Shyam B. "Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease." International Journal of Dermatology 51, no. 1 (December 20, 2011): 111. http://dx.doi.org/10.1111/j.1365-4632.2011.05162.x.

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Canibe, Nuria, and Bent Borg Jensen. "Fermented liquid feed—Microbial and nutritional aspects and impact on enteric diseases in pigs." Animal Feed Science and Technology 173, no. 1-2 (April 2012): 17–40. http://dx.doi.org/10.1016/j.anifeedsci.2011.12.021.

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Lata Kanyal Butola, Anjali Vaaga, Neelam Gusain, and Karuna Kachhwa. "Aspects of dietary fibre in health and diseases." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (December 21, 2020): 1581–86. http://dx.doi.org/10.26452/ijrps.v11ispl4.4341.

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Dietary fibre is the name collectively given to the indigestible carbohydrates present in foods. These carbohydrates consist of cellulose, gum, pectin and mucilage. Enzymes of gastro-intestinal tracts in humans do not digest these fibres. Plants are the only source of dietary fibre. It is found in grains, vegetables and fruits. Dietary fibre helps to keep the digestive system healthy, and it is vital in reducing the risk of diseases such as coronary heart disease, diabetes, diverticulosis, haemorrhoids and intestinal cancer. Undigested fibres enter the large intestine where bacteria ferments them. Carbon dioxide, nitrogen, hydrogen and short-chain fatty acids are the by-products of the fermentation. Soluble fibre and resistant starch also serve as prebiotic and supports the necessary probiotic for digestive health. In grapes, peas, beans and barley, much of the soluble fibre is extracted. When dissolved in the water, a gel-like substance is formed. Soluble fibre helps to support the growth of friendly bacteria needed to maintain a healthy intestinal system. They also help in slowing down the time taken by the food to pass through the stomach into the small intestine, which helps to slow down the absorption of glucose and controls the blood sugar levels and helps in managing diabetes mellitus and keeps you feeling fuller for a longer time. The diets with high fibre intakes are known to have beneficial health effects as they have water holding capacity, helps in adsorption of organic molecules and facilitates its excretion, hypoglycemic effects and hypercholesterolemic effect. The inclusion of fibre rich food in weight-reducing diets is found to helpful since it provides a feeling of fullness without consumption of excess calories. The present review discusses the definition, nutritional properties of dietary fibre and therapeutic functions of dietary fibres in health and diseases.

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Pluhator, Michelle M., Alan Br Thomson, and Richard N. Fedorak. "Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity." Canadian Journal of Gastroenterology 10, no. 2 (1996): 97–103. http://dx.doi.org/10.1155/1996/492792.

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Available evidence suggests that trace elements, such as zinc, once thought to have no nutritional relevance, are possibly deficient in large sections of the human population. Conditioned deficiencies have been reported to result from malabsorption syndromes, acrodermatitis enteropathica, alcoholism, gastrointestinal disease, thermal injury, chronic diseases (eg, diabetes, sickle cell anemia), and in total parenteral nutrition therapy. Awareness that patients with these problems are at risk has led health professionals to focus increasingly on the importance of zinc therapy in the prevention and treatment of deficiency. More recently zinc toxicity and its role in human nutrition and well-being have come under investigation. Reports have focused on the role of zinc toxicity in causes of copper deficiency, changes in the immune system and alterations in blood lipids. As the numerous challenges presented by the study of zinc in human nutrition are met, more appropriate recommendations for dietary and therapeutic zinc intake are being made.

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Tkachenko, E. I., V. B. Grinevich, E. S. Ivanyuk, and Y. A. Kravchuk. "Nutritional Aspects of Therapeutic Problem in the Era of Paradigm Shifts." Experimental and Clinical Gastroenterology, no. 12 (January 14, 2022): 5–14. http://dx.doi.org/10.31146/1682-8658-ecg-196-12-5-14.

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The authors consider the nutriciology aspects of therapeutical problems from the perspectives of the General theory of medicine developed by them — the theory of noosphere–anthropogenic harmony. The authors consider the evolution aspects new scientifi c data on the molecular biology, microbiology and biotechnology as a part of biological culture, which determines the relationship of a person with the internal and external world and is one of the main factors in the evolution of the biosphere. The article analyzes the problems of qualitative and quantitative changes in nutrition parameters during the formation of diseases, their prevention and treatment.

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Круглякова, Людмила, Lyudmila Kruglyakova, Светлана Нарышкина, Svetlana Naryshkina, Андрей Одиреев, and Andrey Odireev. "MODERN ASPECTS OF COMMUNITY-ACQUIRED PNEUMONIA." Bulletin physiology and pathology of respiration 1, no. 71 (March 25, 2019): 120–34. http://dx.doi.org/10.12737/article_5c89acc410e1f3.79881136.

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Thanks to a large number of studies on community-acquired pneumonia (CAP) by scientists around the world, new data are emerging on various aspects of the problem. Therefore, it is necessary to regularly update knowledge on this issue. Despite the tendency to decrease in recent years, the incidence of CAP is 5-10 cases per 1 thousand of the population. In the structure of the general morbidity of respiratory diseases, CAP ranks 2nd in the adult population and 1st in children. Mortality from CAP ranges from 5% to 25-50% depending on the severity, mechanisms of development and personality of the patient (age, nutritional status, concomitant diseases, immune system, etc.), increasing with the growth of diseases of the upper respiratory tract caused by pneumotropic viruses. The clinical lecture presents current data on the features of etiology, previously little known mechanisms of the pathogenesis of CAP, the clinic of typical bacterial, viral, fungal, mycoplasmic and parasitic CAP, as well as the features of the disease in patients with severe immune disorders (AIDS, other diseases/pathological conditions) and aspiration pneumonia. In short form there are discussed the main recommendations for the treatment of CAP in various clinical groups: outpatients, persons with mild CAP, patients with severe CAP with suspected infection with Pseudomonas aeruginosa and aspiration.

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Král, Jan, Evžen Machytka, Veronika Horká, Jana Selucká, Filip Doleček, Julius Špičák, Viktorie Kovářová, Martin Haluzík, and Marek Bužga. "Endoscopic Treatment of Obesity and Nutritional Aspects of Bariatric Endoscopy." Nutrients 13, no. 12 (November 26, 2021): 4268. http://dx.doi.org/10.3390/nu13124268.

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Obesity is a significant problem worldwide. Several serious diseases that decrease patient quality of life and increase mortality (high blood pressure, dyslipidaemia, type 2 diabetes etc.) are associated with obesity. Obesity treatment is a multidisciplinary and complex process that requires maximum patient compliance. Change of lifestyle is fundamental in the treatment of obesity. While pharmacotherapeutic options are available, their efficacy is limited. Surgical treatment though highly effective, carries the risk of complications and is thus indicated mostly in advanced stages of obesity. Endoscopic treatments of obesity are less invasive than surgical options, and are associated with fewer complications and nutritional deficits. Currently, there is a large spectrum of endoscopic methods based on the principles of gastric volume reduction, size restriction and gastric or small bowel bypass being explored with only few available in routine practice. The aim of this publication is to present an up-to-date summary of available endoscopic methods for the treatment of obesity focusing on their efficacy, safety and nutritional aspects.

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Seabra, Larissa Mont'Alverne Jucá, and Lucia Fátima Campos Pedrosa. "Astaxanthin: structural and functional aspects." Revista de Nutrição 23, no. 6 (December 2010): 1041–50. http://dx.doi.org/10.1590/s1415-52732010000600010.

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Astaxanthin, a carotenoid belonging to the xanthophyll class, has stirred great interest due to its antioxidant capacity and its possible role in reducing the risk of some diseases. Astaxanthin occurs naturally in microalgae, such as Haematococcus pluvialis and the yeast Phaffia rhodozyma, and has also been considered to be the major carotenoid in salmon and crustaceans. Shrimp processing waste, which is generally discarded, is also an important source of astaxanthin. The antioxidant activity of astaxanthin has been observed to modulate biological functions related to lipid peroxidation, having beneficial effects on chronic diseases such as cardiovascular disease, macular degeneration and cancer. Researches have shown that both astaxanthin obtained from natural sources and its synthetic counterpart produce satisfactory effects, but studies in humans are limited to natural sources. There is no established nutritional recommendation regarding astaxanthin daily intake but most studies reported beneficial results from a daily intake of 4mg. Thus, this review discusses some aspects of the carotenoid astaxanthin, highlighting its chemical structure and antioxidant activity, and some studies that report its use in humans.

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Moeeni, V., and A. S. Day. "Impact of Inflammatory Bowel Disease upon Growth in Children and Adolescents." ISRN Pediatrics 2011 (April 5, 2011): 1–5. http://dx.doi.org/10.5402/2011/365712.

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The inflammatory bowel diseases (IBDs) are chronic inflammatory processes affecting the gastrointestinal tract. When diagnosed in childhood and adolescence, IBD almost always impacts adversely upon the nutritional state of the patient. Weight loss and impaired linear growth may be present at diagnosis or subsequently. Further potential nutritional consequences in childhood IBD include malnutrition, anaemia, osteopaenia, and delayed puberty. Understanding the nutritional aspects of IBD is paramount in growing children, especially those entering and advancing through puberty. This paper focuses upon the nutritional impacts of IBD in children and adolescents.

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Nesheim, M. C. "Human nutrition needs and parasitic infections." Parasitology 107, S1 (January 1993): S7—S18. http://dx.doi.org/10.1017/s0031182000075478.

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The series of articles that follow in this volume deals with specific aspects of how parasites might influence nutrient utilization by their human hosts. To put these aspects of parasitic disease in context, this contribution is intended to provide an overview of human nutritional needs and to introduce concepts of how nutritional consequences of parasitic infection might be viewed. Although parasitic diseases are often considered to be those caused by protozoa and helminths, the principles considered here can be applied to any infectious agent, including bacteria and viruses.

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Miller, Tracie L. "Nutritional aspects of HIV-infected children receiving highly active antiretroviral therapy." AIDS 17 (April 2003): S130—S140. http://dx.doi.org/10.1097/00002030-200304001-00016.

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Palego, Lionella, Laura Betti, Alessandra Rossi, and Gino Giannaccini. "Tryptophan Biochemistry: Structural, Nutritional, Metabolic, and Medical Aspects in Humans." Journal of Amino Acids 2016 (January 12, 2016): 1–13. http://dx.doi.org/10.1155/2016/8952520.

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L-Tryptophan is the unique protein amino acid (AA) bearing an indole ring: its biotransformation in living organisms contributes either to keeping this chemical group in cells and tissues or to breaking it, by generating in both cases a variety of bioactive molecules. Investigations on the biology of Trp highlight the pleiotropic effects of its small derivatives on homeostasis processes. In addition to protein turn-over, in humans the pathways of Trp indole derivatives cover the synthesis of the neurotransmitter/hormone serotonin (5-HT), the pineal gland melatonin (MLT), and the trace amine tryptamine. The breakdown of the Trp indole ring defines instead the “kynurenine shunt” which produces cell-response adapters as L-kynurenine, kynurenic and quinolinic acids, or the coenzyme nicotinamide adenine dinucleotide (NAD+). This review aims therefore at tracing a “map” of the main molecular effectors in human tryptophan (Trp) research, starting from the chemistry of this AA, dealing then with its biosphere distribution and nutritional value for humans, also focusing on some proteins responsible for its tissue-dependent uptake and biotransformation. We will thus underscore the role of Trp biochemistry in the pathogenesis of human complex diseases/syndromes primarily involving the gut, neuroimmunoendocrine/stress responses, and the CNS, supporting the use of -Omics approaches in this field.

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Vasiloglou, Fletcher, and Poulia. "Challenges and Perspectives in Nutritional Counselling and Nursing: A Narrative Review." Journal of Clinical Medicine 8, no. 9 (September 18, 2019): 1489. http://dx.doi.org/10.3390/jcm8091489.

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Nutritional counselling has been recognised as the first line approach in the management of numerous chronic diseases. Though usually carried out by dietitians, nutritional counselling may be used by nurses, or other healthcare professionals to improve nutritional status and meet healthcare goals. Healthcare professionals require training and education to facilitate a patient centred approach to effective counselling. Advances in digital technology have the potential to improve access to nutritional counselling for some patients such as those in primary care. However, caution is required to ensure that valuable interpersonal relationships are not lost, as these form the cornerstone of effective nutritional counselling. The aim of this narrative review is to explore aspects of effective nutritional counselling, including advances in e-counselling and areas where nursing input in nutritional counselling might enhance overall nutritional care.

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Ivanchenko, S. V., O. M. Kovalyova, and A. B. Andrusha. "THE ROLE OF ASSESSMENT AND CORRECTION OF NUTRITIONAL STATUS IN A COMPREHENSIVE APPROACH TO COVID-19 PATIENT WITH METABOLIC DISORDERS: Review." Inter Collegas 8, no. 3 (December 9, 2021): 152–56. http://dx.doi.org/10.35339/ic.8.3.152-156.

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The article is devoted to the problem of coronavirus disease COVID-19 with emphasis on the nutritional status of patients. An analytical review of recent publications related to aspects of nutritional support for people in outpatient and inpatient treatment for COVID-19 is presented. The article highlights the pathogenetic justification of the relationship between the immune response and metabolic balance of the body, the optimal content of trace elements, vitamins, components of lipid metabolism. The importance of nutrition as a strategy to support human immune function is considered. Methods for determining the adequate energy balance of patients with severe COVID-19 are presented. Groups of foods and key nutrients that may affect the consequences and clinical course of respiratory infections are described. The importance of assessing and optimizing nutritional status to improve the clinical course and consequences of COVID-19 in patients with comorbid pre-existing non-communicable diseases, such as diabetes, cardiovascular disease, obesity with systemic inflammation, is emphasized.

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Hussain, M. Iftikhar, Muhammad Farooq, Qamar Abbas Syed, Anum Ishaq, Abdullah Ahmed Al-Ghamdi, and Ashraf A. Hatamleh. "Botany, Nutritional Value, Phytochemical Composition and Biological Activities of Quinoa." Plants 10, no. 11 (October 22, 2021): 2258. http://dx.doi.org/10.3390/plants10112258.

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Quinoa is a climate-resilient food grain crop that has gained significant importance in the last few years due to its nutritional composition, phytochemical properties and associated health benefits. Quinoa grain is enriched in amino acids, fiber, minerals, phenolics, saponins, phytosterols and vitamins. Quinoa possesses different human-health promoting biological substances and nutraceutical molecules. This review synthesizes and summarizes recent findings regarding the nutrition and phytochemical properties of quinoa grains and discusses the associated biological mechanisms. Quinoa grains and grain-based supplements are useful in treating different biological disorders of the human body. Quinoa is being promoted as an exceptionally healthy food and a gluten-free super grain. Quinoa could be used as a biomedicine due to the presence of functional compounds that may help to prevent various chronic diseases. Future research needs to explore the nutraceutical and pharmaceutical aspects of quinoa that might help to control different chronic diseases and to promote human health.

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Dragasevic, Sanja, Biljana Stankovic, Nikola Kotur, Aleksandra Sokic Milutinovic, Tamara Milovanovic, Milica Stojkovic Lalosevic, Maja Stojanovic, Sonja Pavlovic, and Dragan Popovic. "Genetic Aspects of Micronutrients Important for Inflammatory Bowel Disease." Life 12, no. 10 (October 18, 2022): 1623. http://dx.doi.org/10.3390/life12101623.

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Inflammatory bowel disease (IBD), Crohn’s disease (CD) and ulcerative colitis (UC) are complex diseases whose etiology is associated with genetic and environmental risk factors, among which are diet and gut microbiota. To date, IBD is an incurable disease and the main goal of its treatment is to reduce symptoms, prevent complications, and improve nutritional status and the quality of life. Patients with IBD usually suffer from nutritional deficiency with imbalances of specific micronutrient levels that contribute to the further deterioration of the disease. Therefore, along with medications usually used for IBD treatment, therapeutic strategies also include the supplementation of micronutrients such as vitamin D, folic acid, iron, and zinc. Micronutrient supplementation tailored according to individual needs could help patients to maintain overall health, avoid the triggering of symptoms, and support remission. The identification of individuals’ genotypes associated with the absorption, transport and metabolism of micronutrients can modify future clinical practice in IBD and enable individualized treatment. This review discusses the personalized approach with respect to genetics related to micronutrients commonly used in inflammatory bowel disease treatment.

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Zanoaga, Oana, Cornelia Braicu, Paul Chiroi, Nutu Andreea, Nadim Al Hajjar, Simona Mărgărit, Schuyler S. Korban, and Ioana Berindan-Neagoe. "The Role of miR-155 in Nutrition: Modulating Cancer-Associated Inflammation." Nutrients 13, no. 7 (June 29, 2021): 2245. http://dx.doi.org/10.3390/nu13072245.

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Nutrition plays an important role in overall human health. Although there is no direct evidence supporting the direct involvement of nutrition in curing disease, for some diseases, good nutrition contributes to disease prevention and our overall well-being, including energy level, optimum internal function, and strength of the immune system. Lately, other major, but more silent players are reported to participate in the body’s response to ingested nutrients, as they are involved in different physiological and pathological processes. Furthermore, the genetic profile of an individual is highly critical in regulating these processes and their interactions. In particular, miR-155, a non-coding microRNA, is reported to be highly correlated with such nutritional processes. In fact, miR-155 is involved in the orchestration of various biological processes such as cellular signaling, immune regulation, metabolism, nutritional responses, inflammation, and carcinogenesis. Thus, this review aims to highlight those critical aspects of the influence of dietary components on gene expression, primarily on miR-155 and its role in modulating cancer-associated processes.

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Journal articles on the topic 'Diseases Nutritional aspects'

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