Academic literature on the topic 'Discordant colour'

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Journal articles on the topic "Discordant colour"

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Mancuso, Patrizia, Elisabetta Muratori, Cristina Rabascio, Angelica Calleri, Chiara Corsini, and Francesco Bertolini. "Lymphoma Cell Detection and Follow-Up in the Rituximab Era: Concordance between Flow Cytometry, Qualitative/Quantitative PCR and FISH in the Marrow and Blood from 647 Patients." Blood 104, no. 11 (November 16, 2004): 1376. http://dx.doi.org/10.1182/blood.v104.11.1376.1376.

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Abstract The anti-CD20 monoclonal antibody Rituximab is now widely used in B-cell non-Hodgkin’s lymphoma (NHL) and chronic lymphocytic leukemia (CLL) patients. Its administration is associated with a profound reduction of the number of normal and malignant CD20+ B cells, so that the procedures used so far for NHL and CLL diagnosis, detection of minimal residual disease (MRD) and follow-up (F-UP) should be revised. We have retrospectively evaluated our consecutive 4-year record of 647 NHL and CLL patients. Our aims were: 1) to compare sensitivity and concordance between 4-colour flow cytometry, qualitative and quantitative PCR and FISH. 2) to compare concordance between bone marrow (BM) and peripheral blood (PB). Sensitivity of the procedures (evaluated by serial dilution of NHL cell lines in healthy donors’ BM and PB) were found to be 10−5, 10−6, 10−4/5 and 10−3 for 4-colour flow cytometry, qualitative PCR, quantitative PCR and FISH, respectively. A total of 955 paired BM and PB samples were investigated. Most frequent diagnoses were follicular NHL (29%), diffuse large B-cell NHL (22%), marginal zone NHL (11%), CLL (10%), and mantle cell NHL (8%). In 236/955 cases (25%), 4-color flow cytometry identified a monoclonal or a phenotypically aberrant cell population. Concordance between BM and PB was 87% (p<0.001). Most frequent diagnosis of discordant cases was lymphoplasmocytoid-Waldenstrom NHL (36% of discordant cases). Qualitative and quantitative PCR were used to investigate clonality (Fr2A/VLJH and Fr2A/VLJH genes) and the presence of translocations involving BCL-1 or BCL-2 genes (in mantle cell or follicular NHL, respectively). A total of 91/333 samples (27%) were positive. Concordance between BM and PB was 91% (p<0.001). Discordance was found in 11% of mantle cells NHL and 8% of follicular NHL cases. When 118 patients were evaluated 3-month after Rituximab (alone or in combination with chemotherapy), qualitative PCR still detected malignant cells in 95% of previously PCR-positive patients, flow cytometry in 72% of previously cytometry-positive patients. On the other hand, at 7 month after Rituximab, in these patients malignant cells were found by qualitative PCR in 14/72 (19%) cases, by flow-cytometry in 22/118 (19%) cases. These procedures identified disease persistence or recurrence significantly earlier than quantitative PCR (evaluated in 98 cases, p<0.01) and FISH (evaluated in 11 cases, p<0.001). We conclude that 1) BM and PB examination by means of 4-color flow cytometry and qualitative PCR offer nearly-overlapping results. In Rituximab-treated patients, differences seen at 3-month F-UP, probably due to the higher sensitivity of qualitative PCR, are no more observed at 7-month F-UP. 2) Four-color flow cytometry and qualitative PCR have higher sensitivity and detect MRD and relapses significantly earlier than quantitative PCR and FISH. 3) With the exception of lymphoplasmocytoid-Waldenstrom NHL, PB examination may be considered a sensitive and specific alternative to BM examination in NHL and CLL patients, including those treated with Rituximab.
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Mano, Pavan. "Disarming as a tactic of resistance in Pink Dot." Pink Dot 10, no. 2 (July 16, 2021): 129–56. http://dx.doi.org/10.1075/jls.20008.man.

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Abstract Pink Dot is an annual rally in support of LGBT (lesbian, gay, bisexual, and transgender) people in Singapore. In a country where many prefer to avoid overt displays of dissent, Pink Dot has gained significant popular support. In this article, I explore how it has done so. Through a close multimodal analysis focusing on the use of colour, layout, and typography in a Pink Dot 2017 flyer, I demonstrate how these features work together in the Singaporean context to realize meanings of positivity, warmth, and inclusivity whilst simultaneously de-emphasizing notions of claiming rights. I argue Pink Dot discursively attenuates the potentially discordant elements of its message and marshals this apparent neutrality to gather support for its ostensibly depoliticized message – a process that I term disarming. It is an assimilationist strategy deliberately made for Singapore’s particular sociopolitical context and it has proven effective in securing mass popular support amongst Singaporeans.
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Beck, O., M. Kraft, M. R. Moeller, B. L. Smith, S. Schneider, and R. Wennig. "Frontline ® immunochromatographic device for on-site urine testing of amphetamines: laboratory validation using authentic specimens." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 37, no. 2 (March 1, 2000): 199–204. http://dx.doi.org/10.1258/0004563001899005.

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We evaluated a new test device for amphetamines and methamphetamines (Frontline ®, cut-off limit 300 ng/mL) using authentic clinical and forensic specimens. The device is based on immunochromatography and is dipped into urine and read visually by comparison with a colour scale after a few minutes. A total of 658 specimens were tested by comparing results of the screening procedure with established immunoassays. Discordant results were further investigated by gas chromatography- mass spectrometry or gas chromatography (with flame ionization detector). The Frontline device had a sensitivity of 93% and a specificity of 98%. When specimens were classified by urine amphetamine concentration, close agreement was obtained at concentrations below 150 ng/mL and above 1000 ng/mL. A small number of specimens with amphetamine concentrations between 300 and 1000 ng/mL tested negative in the Frontline test. This finding could to some extent be explained by the enantioselectivity of the antibodies in the Frontline test to d-amphetamine. We conclude that the performance of the Frontline test device for amphetamines is adequate for presumptive clinical and forensic screening.
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Kröber, Alexander, Dirk Kienle, Dirk Winkler, Andreas Bühler, Till Seiler, Christine Schöpflin, Sabrina Kless, Claire Paulus, Hartmut Döhner, and Stephan Stilgenbauer. "ZAP-70 Expression, VH-Mutation Status, Genomic Aberrations and Prognosis in Chronic Lymphocytic Leukemia." Blood 104, no. 11 (November 16, 2004): 1920. http://dx.doi.org/10.1182/blood.v104.11.1920.1920.

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Abstract The VH status is a strong prognostic marker in chronic lymphocytic leukemia (CLL). ZAP-70, a zeta associated tyrosine kinase physiologically expressed by T-cells, is overexpressed in VH unmutated CLL and could therefore serve as a surrogate marker for the VH status. We analyzed ZAP-70 expression (n=96), the VH status (n=75) and genomic aberrations (n=84) in a single center CLL cohort to study associations among these parameters and to assess their relative prognostic value. ZAP-70 expression was measured by 4-colour flow cytometry (CD5, CD19, CD3/56, ZAP-70) applying an unconjugated anti-ZAP-70-antibody (Upstate, clone 2F3.2) according to Crespo et al., NEJM 2003. ZAP-70 expression was positive (cut-off 20%) in 67% and negative in 33% of cases. VH was mutated in 33% and unmutated in 67% of cases. Unfavorable genomic aberrations (17p−, 11q−) were more frequently observed in cases with unmutated VH (46 vs. 9%) and in ZAP-70 positive cases (39 vs. 20%), while favorable genomic aberrations (13q− as single aberration) occurred more frequently in VH mutated (48 vs. 17%) and ZAP-70 negative subgroups (50 vs. 18%). ZAP-70 expression predicted the VH status in 84% of cases. At a median follow up time of 47 months (m), the median treatment free survival (TFS) of ZAP-70 positive and negative cases was 31 and 86 m (p=.057). The median TFS of the VH unmutated and VH mutated subgroups were 24 and 172 m (p<.001). Within the follow up time 10 deaths occurred. Of these, 8 cases exhibited high ZAP-70 expression and an unmutated VH, whereas 2 cases showed discordant results. Overall, discordant results for ZAP-70 expression and VH status were identified in 12 cases (ZAP-70 positive/VH mutated, 8 cases; ZAP-70 negative/VH unmutated, 4 cases). Of the 8 VH mutated cases with high ZAP-70 expression, only 1 case exhibited unfavorable genomic aberrations, 4 remained in stable disease, 4 developed progressive disease, 3 patients required therapy, and 1 of these 3 died within follow up time. Two of the 3 patients who required therapy, including the patient who died, showed a mutated V3-21 gene rearrangement, associated with an unfavorable outcome. Among the 4 cases with an unmutated VH and low ZAP-70 expression, 2 cases exhibited unfavorable genomic aberrations, 3 cases required therapy, 1 of these 3 died, and for one patient no clinical data were available. In summary, the imbalanced distribution of high risk genomic aberrations was similar when comparing the subgroups according to ZAP-70 expression and VH status. In our series an unmutated VH status predicted for shorter TFS, whereas high ZAP-70 expression did not reach significance. ZAP-70 expression was associated with unmutated VH, but a substantial number of cases showed discordant results for ZAP-70 expression and VH status. The pattern of genomic aberrations and the clinical course of the discordant cases were typical for their respective VH status. Compared to ZAP-70 expression the VH status appeared to be more informative in the prediction of the clinical course in our series of CLL patients.
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Kumar, Ishan, Shivi Jain Shivi Jain, Ashish Verma, Madhu Jain Madhu Jain, Ram C. Shukla, and Arvind Srivastava. "Discordant Twin Pregnancy with One Malformed Fetus – Color Doppler Follow Up for Expectant Management." Indian Journal of Applied Research 3, no. 9 (October 1, 2011): 469–72. http://dx.doi.org/10.15373/2249555x/sept2013/142.

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Phipps, J. B. "Introduction to the red-fruited hawthorns (Crataegus, Rosaceae) of western North America." Canadian Journal of Botany 76, no. 11 (November 1, 1998): 1863–99. http://dx.doi.org/10.1139/b98-148.

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Howell's failure in 1898 to typify Crataegus columbiana Howell (the species is based on noncited discordant paratype elements) and the readiness of later authors to make new varieties in this species without resolving the type problem has been the cause of much confusion in the nomenclature of the western red-fruited hawthorns. This has been increased by the failure to recognize Crataegus williamsii Eggl. and compounded by almost a century of no revisionary study on western Crataegus with the further result that boundaries between taxa have been routinely misunderstood outside Colorado. In pursuit of a solution doing least violence to conventional usage I have lectotypified C. columbiana and resuscitated Crataegus piperi Britton (in a recent paper), realigned C. piperi as Crataegus chrysocarpa var. piperi (Britton) Eggl. and resurrected C. williamsii. There are thus five established native western species of red-fruited hawthorns, the above two, and Crataegus wootoniana Eggl., Crataegus macracantha Lodd. ex Loud. and Crataegus erythropoda Ashe in addition to the introduced Crataegus monogyna Jacq., all of which have been recognized as occurring at least somewhere in this region for many decades. This paper also adds the first authenticated record for wild Crataegus laevigata (Poir.) DC. in North America. Separation of the two varieties of C. chrysocarpa is validated by numerical taxonomy. The taxa concerned are illustrated with line drawings and provided with detailed range maps. Colour photographs illustrate typical habitat types and show the development of fruit colour.Key words: systematics, Crataegus, Rosaceae, red-fruited, western North America.
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Gircys, Michael, and Brian J. Ross. "Image Evolution Using 2D Power Spectra." Complexity 2019 (January 2, 2019): 1–21. http://dx.doi.org/10.1155/2019/7293193.

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Procedurally generated images and textures have been widely explored in evolutionary art. One active research direction in the field is the discovery of suitable heuristics for measuring perceived characteristics of evolved images. This is important in order to help influence the nature of evolved images and thereby evolve more meaningful and pleasing art. In this regard, particular challenges exist for quantifying aspects of style and shape. In an attempt to bridge the divide between computer vision and cognitive perception, we propose the use of measures related to image spatial frequencies. Based on existing research that uses power spectral density of spatial frequencies as an effective metric for image classification and retrieval, we posit that Fourier decomposition can be effective for guiding image evolution. We refine fitness measures based on Fourier analysis and spatial frequency and apply them within a genetic programming environment for image synthesis. We implement fitness strategies using 2D Fourier power spectra and phase, with the goal of evolving images that share spectral properties of supplied target images. Adaptations and extensions of the fitness strategies are considered for their utility in art systems. Experiments were conducted using a variety of greyscale and colour target images, spatial fitness criteria, and procedural texture languages. Results were promising, in that some target images were trivially evolved, while others were more challenging to characterize. We also observed that some evolved images which we found discordant and “uncomfortable” show a previously identified spectral phenomenon. Future research should further investigate this result, as it could extend the use of 2D power spectra in fitness evaluations to promote new aesthetic properties.
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Eyskens, Benedicte, Frank Weidemann, Miroslaw Kowalski, Jan Bogaert, Steven Dymarkowski, Bart Bijnens, Marc Gewillig, George Sutherland, and Luc Mertens. "Regional right and left ventricular function after the Senning operation: an ultrasonic study of strain rate and strain." Cardiology in the Young 14, no. 3 (June 2004): 255–64. http://dx.doi.org/10.1017/s1047951104003038.

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Background:Systemic right ventricular dysfunction is a major concern in the follow-up of patients who underwent an atrial redirection procedure for transposition (concordant atrio-ventricular and discordant ventriculo-arterial connections). No good non-invasive method is currently available for quantifying right ventricular function.Aims:We have used ultrasonically based imaging of strain rate and strain to quantify regional deformation in the right ventricle after the Senning operation, comparing properties of regional deformation of the right ventricle with right ventricular ejection fraction as measured using magnetic resonance imaging.Methods:In 20 asymptomatic patients who had undergone the Senning procedure, we measured peak systolic strain rate and systolic strain values in the right ventricular free wall, the septum and the left ventricular lateral wall using colour Doppler myocardial imaging, comparing the data with findings obtained in 30 healthy subjects. Global right ventricular ejection fraction was assessed using magnetic resonance imaging.Results:Properties of deformation of the right ventricular free wall were reduced and homogeneous after the Senning procedure compared to normals, with significantly lower values for peak systolic strain rate and systolic strain (−1.1 ± 0.4 vs. −2.5 ± 0.9 s−1; p < 0.05 and −16 ± 7% vs. −38 ± 13%; p < 0.05, respectively). There was a significant correlation between regional longitudinal right ventricular systolic strain values and right ventricular ejection fraction (r = −0.87, p < 0.001). In the septum, peak systolic strain rate was again reduced and homogeneous (−1.2 ± 0.4 vs. −1.8 ± 0.5 s−1; p < 0.05 vs. normals). Also in the left ventricle, the lateral wall peak systolic strain rate and systolic strain values were reduced (−1.5 ± 0.5 vs. −2.1 ± 0.9 s−1; p < 0.05 and −20 ± 6% vs.−25 ± 9%; p < 0.05, vs. normals, respectively).Conclusions:Properties of regional longitudinal deformation of the systemic right ventricle are reduced after the Senning procedure compared to normal controls, and correlate well with global right ventricular performance. These findings suggest that ultrasonic strain rate and strain imaging could be used in the non-invasive follow-up of ventricular function in these patients.
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Norrsell, Ulf. "Color Vision and Frithiof Holmgren's Discordant Retinal Microstimulation Findings." Journal of the History of the Neurosciences 19, no. 3 (July 9, 2010): 228–38. http://dx.doi.org/10.1080/09647040902997721.

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Elisa de Villemor-Amaral, Anna, Giselle Pianowski, and Lucas de Francisco Carvalho. "Issues About Color, Human Movement, and Number of Responses in the Zulliger Test." Rorschachiana 37, no. 2 (September 2016): 95–113. http://dx.doi.org/10.1027/1192-5604/a000068.

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Abstract. This study aimed to verify the scope and limitations of the stimuli of indicators of Color (C), Human movement (M), and Response number (R) of the Zulliger test through a qualitative analysis of the stimuli present in the Zulliger and the Rorschach, comparisons in expressions of C, M, and R, and R relations with evaluative inconsistencies on Zulliger. Taking the Rorschach as a reference, the qualitative analysis indicated a variation from little equivalence up to an overrepresentativeness of Zulliger stimuli. The comparisons, made with a sample of 51 subjects tested with the Zulliger and Rorschach tests and divided into concordant and discordant groups according to the evaluation of instruments, revealed a significant decrease of C and M for the Zulliger. We also identified a tendency toward a decrease of R on Zulliger for the discordant group. The results reveal distinctions between the instruments, limitations of the Zulliger, and instigate investigations for the R-Optimized Administration.
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Dissertations / Theses on the topic "Discordant colour"

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Latimer, Christine. "The invisible view betwixt and between : exegesis submitted in partial fulfilment of requirements for the degree of Masters of Art & Design, AUT University, November, 2008." Click here to access this resource online, 2008. http://hdl.handle.net/10292/456.

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This thesis explores the idea of a liminal space, as being dreamlike, suspended in time and physically unlocatable. It questions and exploits the boundary between abstraction and figuration in painting. This investigation has been considered from a subjective viewpoint allowing a distancing of space to illuminate new perceptions and experiences through the language of painting. The project has sought to explore the relationship between the natural world and seeing, to deepen and emphasize the other worldliness of an in-between space. This third space has been evoked by a process of abstracting pictorial content, juxtaposition of elements, colour and composition. The thesis is constituted of practice-based 80%, accompanied by an exegesis 20%.
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Book chapters on the topic "Discordant colour"

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Radhakrishnan, Prathima, and Saket Thakar. "Management of Discordant Twins." In Manual of Genetics Fetal Medicine and Color Doppler, 24. Jaypee Brothers Medical Publishers (P) Ltd., 2018. http://dx.doi.org/10.5005/jp/books/18023_7.

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Conference papers on the topic "Discordant colour"

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Bastos, Alberto Freaza Lobão, Amanda Mendes Soares, Nicole Souto Campanario, Amanda Salgueiro Mello, Christiani Ribeiro Pereira, and Yara Lúcia Mendes Furtado de Melo. "Concordância cito-colpo-histológica em uma coorte com preventivo alterado." In 44° Congresso da SGORJ - XXIII Trocando Ideias. Zeppelini Editorial e Comunicação, 2020. http://dx.doi.org/10.5327/jbg-0368-1416-2020130204.

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Introdução: A citologia é o método recomendado pelas Diretrizes Brasileiras para Rastreamento do Câncer do Colo Uterino. Além disso, essas diretrizes fazem recomendações quanto à conduta frente as citologias alteradas. O “ver e tratar” é uma das recomendações quando a citologia é de lesão intraepitelial escamosa de alto grau (HSIL) e a colposcopia é concordante. Objetivo: Verificar a concordância cito-colpo-histológica em mulheres submetidas à excisão tipo 1, a margem cirúrgica e os resultados do “ver e tratar” em um ambulatório de patologia cervical em hospital universitário no Rio de Janeiro. Métodos: Estudo de corte transversal no qual foram selecionadas mulheres encaminhadas para o Instituto de Ginecologia da Universidade Federal do Rio de Janeiro (IG-UFRJ) para colposcopia após citologia de rastreio alterada. Verificou-se concordância cito-colposcópica e cito-colpo-histológica. A concordância cito-colposcópica foi observada quando o laudo citológico foi de ASC-H (células atípicas de significado indeterminado, não podendo excluir lesão de alto grau), HSIL e HSIL/invasão, e a colposcopia sugeria HSIL ou HSIL/invasão. A concordância cito-colpo-histológica foi observada quando também houve concordância com o laudo histológico. Avaliou-se o comprometimento das margens cirúrgicas da excisão tipo 1 e se foi realizada a estratégia “ver e tratar”. Resultados: Neste estudo, foram selecionadas 33 mulheres com média de idade de 32,6 anos. Na citologia de encaminhamento, 21 delas (63,6%) tinham laudo de HSIL; dez (30,3%), ASC-H; e duas (6,1%), lesão intraepitelial escamosa de baixo grau (LSIL). Na colposcopia, em 31 mulheres (93,9%) foram observados achados maiores, sugerindo HSIL, e em duas (6,1%), achados menores, sugerindo LSIL. Os laudos histopatológicos apontaram três pacientes (1%) com carcinoma escamoso microinvasor, 19 (57,6%) com neoplasia intraepitelial cervical grau 3 (NIC 3), 10 (30,3%) com NIC 2 e uma (3,0%) com NIC 1. As margens estavam comprometidas em 15 mulheres (45,5%) e livres em 17 (51,5%), e uma delas (3,0%) estava sem status das margens. Houve concordância cito-colposcópica de HSIL em 84,8% dos casos (28/33), e observou-se discordância em 18,2% do total de mulheres (5/33), sendo três citologias LSIL com colposcopia HSIL; uma citologia ASC-H; e uma HSIL com colposcopia LSIL. Houve concordância cito-colpo-histológica em 81,8% dos casos (27/33), e nos 18,2% (6/33) discordantes, os resultados foram: quatro casos de NIC 3 (uma citologia ASC-H com colposcopia LSIL e três citologias LSIL com colposcopia HSIL); um caso de NIC 2 (citologia HSIL com colposcopia LSIL); e um caso de NIC 1 com análise cito-colposcópica HSIL. A estratégia “ver e tratar” foi realizada em 22 mulheres (66,7%), das quais apenas uma (3%) apresentou resultado NIC 1, 15 (68,18%) apresentaram NIC 3/Microinvasor e seis (27,27%), NIC 2. Conclusão: Neste estudo, observou-se alta concordância cito-colposcópica e cito-colpo-histológica. Na aplicação do “ver e tratar”, houve pouca frequência de sobretratamento e, na maioria dos casos, as margens cirúrgicas estavam livres. Esses resultados são relevantes por mostrar o quanto é importante o treinamento em serviço de colposcopia e a resolução com “ver e tratar”.
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