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Relevant bibliographies by topics / Diosgenin yielding

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Academic literature on the topic 'Diosgenin yielding'

Author: Grafiati

Published: 18 May 2024

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Journal articles on the topic "Diosgenin yielding"

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Odimegwu, Joy I., Olukemi Odukoya, Ritesh K. Yadav, C. S. Chanotiya, Steve Ogbonnia, and Neelam S. Sangwan. "A New Source of Elemol Rich Essential Oil and Existence of Multicellular Oil Glands in Leaves of theDioscoreaSpecies." Scientific World Journal 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/943598.

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Dioscoreaspecies is a very important food and drug plant. The tubers of the plant are extensively used in food and drug purposes owing to the presence of steroidal constituent’s diosgenin in the tubers. In the present study, we report for the first time that the leaves ofDioscorea compositaandDioscorea floribundagrown under the field conditions exhibited the presence of multicellular oil glands on the epidermal layers of the plants using stereomicroscopy (SM) and scanning electron microscopy (SEM). Essential oil was also isolated from the otherwise not useful herbage of the plant, and gas chromatographic-mass spectroscopy analysis revealed confirmation of the essential oil constituents. Out of the 76 compounds detected inD. floribundaand 37 fromD. compositaessential oil, major terpenoids which are detected and reported forDioscorealeaf essential oil areα-terpinene, nerolidol, citronellyl acetate, farnesol, elemol,α-farnesene, valerenyl acetate, and so forth. Elemol was detected as the major constituent of both theDioscoreaspecies occupying 41% and 22% ofD. FloribundaandD. compositaessential oils, respectively. In this paper, we report for the first timeDioscoreaas a possible novel bioresource for the essential oil besides its well-known importance for yielding diosgenin.

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2

Ravishankar, G. A., and S. Grewal. "A simple and rapid method for selection of high diosgenin yielding clones ofDioscorea deltoidea callus." Biotechnology Techniques 5, no. 4 (July 1991): 281–82. http://dx.doi.org/10.1007/bf02438663.

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3

Özdemir, Zülal, Michaela Rybková, Martin Vlk, David Šaman, Lucie Rárová, and Zdeněk Wimmer. "Synthesis and Pharmacological Effects of Diosgenin–Betulinic Acid Conjugates." Molecules 25, no. 15 (August 3, 2020): 3546. http://dx.doi.org/10.3390/molecules25153546.

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The target diosgenin–betulinic acid conjugates are reported to investigate their ability to enhance and modify the pharmacological effects of their components. The detailed synthetic procedure that includes copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition (click reaction), and palladium-catalyzed debenzylation by hydrogenolysis is described together with the results of cytotoxicity screening tests. Palladium-catalyzed debenzylation reaction of benzyl ester intermediates was the key step in this synthetic procedure due to the simultaneous presence of a 1,4-disubstituted 1,2,3-triazole ring in the molecule that was a competing coordination site for the palladium catalyst. High pressure (130 kPa) palladium-catalyzed procedure represented a successful synthetic step yielding the required products. The conjugate 7 showed selective cytotoxicity in human T-lymphoblastic leukemia (CEM) cancer cells (IC50 = 6.5 ± 1.1 µM), in contrast to the conjugate 8 showing no cytotoxicity, and diosgenin (1), an adaptogen, for which a potential to be active on central nervous system was calculated in silico. In addition, 5 showed medium multifarious cytotoxicity in human T-lymphoblastic leukemia (CEM), human cervical cancer (HeLa), and human colon cancer (HCT 116). Betulinic acid (2) and the intermediates 3 and 4 showed no cytotoxicity in the tested cancer cell lines. The experimental data obtained are supplemented by and compared with the in silico calculated physico-chemical and absorption, distribution, metabolism, and excretion (ADME) parameters of these compounds.

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Pal, A., and A. Roy. "Embryo culture of Costus speciosus (Koen.) Sm. to regenerate variable diosgenin yielding clones." Plant Cell Reports 10, no. 11 (December 1991). http://dx.doi.org/10.1007/bf00232512.

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5

Nazir, Romaan, Suphla Gupta, Abhijit Dey, Vijay Kumar, Muzamil Yousuf, Shahnawaz Hussain, Padmanabh Dwivedi, and Devendra Kumar Pandey. "In vitro propagation and assessment of genetic fidelity in Dioscorea deltoidea, a potent diosgenin yielding endangered plant." South African Journal of Botany, August 2020. http://dx.doi.org/10.1016/j.sajb.2020.07.018.

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6

Sethi, Arun, Ranvijay Pratap Singh, Akriti Bhatia, and Priyanka Yadav. "Efficient Synthesis and Spectroscopic Characterization of Biologically Relevant Pregnane Derivatives, and its Glycoside." Current Chinese Chemistry 01 (October 29, 2020). http://dx.doi.org/10.2174/2666001601999201029204603.

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Objective:: In present research article, we synthesized novel pregnane derivatives from 16-dehydropregnenolone acetate (1) which has been obtained by the degradation of naturally occurring plant product-diosgenin. The oxime esters, 3β-acetoxy-pregn-5,16-diene, 20-one O-(2-(6-methoxynaphthalene-2yl) propionyl) oxime (5) and 3β-hydroxy-pregn-5, 16-diene, 20-one O-(2-(4-isobutyl phenyl) propionyl) oxime (6) have been synthesized by reaction of 3β-acetoxy-5,16-pregna-dien-20-oxime (3) with NSAIDs Ibuprofen and naproxen respectively. Methods:: The epoxide derivative 3β-hydroxy-16α, 17α-epoxypregn-5-ene-20-one (4) was opened by BF3.Et2O and yielding product 3,16-di-hydroxy pregn-5-ene-20-one (7) and 3,16,17-tri-hydroxy pregn-5-ene-20-one (8), both the synthesized compounds undergoes esterification with Ibuprofen afforded 3,16-di-(2-(4-isobutyl phenyl) propionoxy) pregn-5-ene-20-one (9) and 3,16-di-(2-(4-isobutyl phenyl) propionoxy) 17-hydroxy pregn-5-ene-20-one (10) respectively. Results and Conclusion:: A one novel pregnane glycoside 3β-[2′,3′,4′,6′-tetra-O-acetyl-β-D-glucopyranosyl]-Oxy-20β-hy-droxy-16α-methoxy-pregn-5-ene (15) has also been synthesized from 3β, 20β-dihydroxy-16α-methoxy-pregn-5-ene (12). After the synthesis all the compounds have been characterized by modern spectroscopic techniques.

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Dissertations / Theses on the topic "Diosgenin yielding"

1

Mandal, Asitbaran. "Eco-physiological investigations on commercially important diosgenin yielding plants in Darjeeling District." Thesis, University of North Bengal, 1990. http://hdl.handle.net/123456789/912.

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Saha, Pranab Kumar. "Studies on agronomy and development physiology of commercially cultivated diosgenin yielding dioscorea sp. in Darjeeling hills, West Bengal." Thesis, University of North Bengal, 1990. http://hdl.handle.net/123456789/1112.

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Book chapters on the topic "Diosgenin yielding"

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Cruel Sigüenza, Joseph, Carla Bernal Villavicencio, María Elizabeth Canchingre, Christie Durán García, and Juan E. Tacoronte. "Eco-Sustainable Catalytic System for Green Oxidation of Spirostanic Alcohols Using Hypervalent Iodine (III) Tempo-4-n-Acetoxyamine System." In Green Chemistry - New Perspectives. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.103855.

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The oxidation of the 3β-hydroxy group in the steroidal substrates obtained from naturally occurring sources, i.e., solanaceae steroidal sapogenins, is an important process in the preparation of ecdysteroid analogs. The need for selective green oxidation methodologies for steroidal alcohols (spirostenols, diosgenine, and derivatives) avoid the use of toxic Cr (VI) derivatives, without the isomerization of the double bond at 5,6 position and also without the oxidative cleavage of the spirocetal moiety is of great methodological significance. Herein, we report the oxidation of spirostanic steroidal alcohols to their carbonyl analogs using hypervalent iodine (III)/TEMPO-4-N-acetoxyamine system. The present method is simple, eco-sustainable, efficient, and high-yielding process for the oxidative transformation of secondary steroidal alcohols without any over-oxidation, isomerization of the double bond, or oxidative cleavage of spirocetalic fragment in different substrates. Therefore, this method does not involve toxic heavy metals and is expected to have wide utility in the oxidation process of these compounds.

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