Academic literature on the topic 'Dimethylsulfone'

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Journal articles on the topic "Dimethylsulfone"

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Ghazoyan, Heghine H., and Shiraz A. Markaryan. "VOLUMETRIC PROPERTIES OF SOLUTIONS OF DIMETHYLSULFONE IN ETHANOL-WATER MIXTURE AT TEMPERATURES RANGE OF 298.15-323.15 K." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 60, no. 7 (August 24, 2017): 27. http://dx.doi.org/10.6060/tcct.2017607.5564.

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This paper studies volumetric properties of ternary dimethylsulfone-ethanol-water systems. The biomedical and environmental significance for the fundamental investigations of aqueous solution of dimethylsulfone and influences of third component on volumetric behavior of this system arises from several reasons. In the global sulfur cycle dimethylsulfide is converted to dimethylsulfone leading to an annual atmospheric production of some million tones of dimethylsulfone, much of which would be deposited in rain and snow. In addition, dimethylsulfone has been extensively studied from a medical point of view. It was established that dimethylsulfone is contained in small amounts in human blood and urine. Also of interest is that methionine is transformed into dimethylsulfone in living organisms. In this work densities of solution of dimethylsulfone in ethanol-water mixtures with various compositions have been measured over available concentration range. As it is evident from experimental data, the increase in a temperature leads to the reduction of density. The apparent and partial molar volumes of solutions were determined over the 298.15–323.15K temperature range. As it follows from these data, the apparent molar volumes increase with increasing of temperature. The influence of ethanol on the volumetric behavior has been taken into account by changing the apparent molar volume compared with the apparent molar volume of the binary aqueous solutions of DMSO2. It is found also the effect of the amount of ethanol on the volumetric properties of these solutions. It is interesting that the effect of ethanol on the values of apparent molar volumes does not change monotone with increasing in quantity of ethanol in ethanol-water mixture. In dimethylsulfone+(ethanol-water) solutions the partial molar volume of dimethylsulfone increases when quantity of ethanol in ethanol-water mixture more than 0.5 molar fraction. The observed phenomena are explained by the presence of competition of intermolecular interactions. In the DMSO2-ethanol-water system the strongest interaction between ethanol and water molecules leads to the increase in partial molar volumes for DMSO2.For citation:Ghazoyan H.H., Markaryan S.A. Volumetric properties of solutions of dimethylsulfone in ethanol-water mixture at tempe-ratures range of 298.15-323.15 K. Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol. 2017. V. 60. N 7. P. 27-33.
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Legrand, L., A. Tranchant, R. Messina, F. Romain, and A. Lautie. "Raman Study of Aluminum Chloride−Dimethylsulfone Solutions." Inorganic Chemistry 35, no. 5 (January 1996): 1310–12. http://dx.doi.org/10.1021/ic941455q.

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Harvey, George R., and Russell F. Lang. "Dimethylsulfoxide and dimethylsulfone in the marine atmosphere." Geophysical Research Letters 13, no. 1 (January 1986): 49–51. http://dx.doi.org/10.1029/gl013i001p00049.

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Ramalho-Santos, João, Ricardo Negrão, and Maria da Conceição Pedroso de Lima. "Role of hydrophobic interactions in the fusion activity of influenza and sendai viruses towards model membranes." Bioscience Reports 14, no. 1 (February 1, 1994): 15–24. http://dx.doi.org/10.1007/bf01901634.

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We have studied the role of hydrophobic interactions in the fusion activity of two lipid enveloped viruses, influenza and Sendai. Using the fluorescent probe ANS (1-aminonaphtalene-8-sulfonate) we have shown that low-pH-dependent influenza virus activation involves a marked increase in the viral envelope hydrophobicity. The effect of dehydrating agents on the fusion activity of both viruses towards model lipid membranes was studied using a fluorescence dequenching assay. Dehydrating agents such as dimethylsulfoxide and dimethylsulfone greatly enhanced the initial rate of the fusion process, the effect of dimethylsulfone doubling that of dimethylsulfoxide. The effect of poly(ethylene glycol) on the fusion process was found to be dependent on the polymer concentration and molecular weight. In general, similar observations were made for both viruses. These results stress the importance of dehydration and hydrophobic interactions in the fusion activity of influenza and Sendai viruses, and show that these factors may be generally involved in membrane fusion events mediated by many other lipid enveloped viruses.
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Kim, Sangjae, Shota Kumeno, Kenta Kamebuchi, Kensuke Kuroda, and Masazumi Okido. "Effect of Li Ions on Al Electrodeposition from Dimethylsulfone." Journal of Surface Engineered Materials and Advanced Technology 08, no. 04 (2018): 110–25. http://dx.doi.org/10.4236/jsemat.2018.84010.

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Khibiev, Kh S., K. O. Omarova, and Sh Sh Khidirov. "Electrochemical synthesis of dimethylsulfone and methanesulfonic acid from dimethylsulfoxide." Russian Journal of Electrochemistry 46, no. 8 (August 2010): 960. http://dx.doi.org/10.1134/s1023193510080161.

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Gabrielyan, Liana S., Shiraz A. Markarian, and Hermann Weingärtner. "Dielectric spectroscopy of dimethylsulfone solutions in water and dimethylsulfoxide." Journal of Molecular Liquids 194 (June 2014): 37–40. http://dx.doi.org/10.1016/j.molliq.2014.01.013.

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Legrand, L., A. Tranchant, and R. Messina. "Behaviour of aluminium as anode in dimethylsulfone-based electrolytes." Electrochimica Acta 39, no. 10 (July 1994): 1427–31. http://dx.doi.org/10.1016/0013-4686(94)85054-2.

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Salama, Nahla N., Mohammed A. El Ries, Safaa Toubar, Maha Abd El Hamid, and Mohammed I. Walash. "Thermoanalytical Investigation of Some Sulfone-Containing Drugs." Journal of Analytical Methods in Chemistry 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/439082.

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The thermal behavior of some sulfone-containing drugs, namely, dapsone (DDS), dimethylsulfone (MSM), and topiramate (TOP) in drug substances, and products were investigated using different thermal techniques. These include thermogravimetry (TGA), derivative thermogravimetry (DTG), differential thermal analysis (DTA), and differential scanning calorimetry (DSC). The thermogravimetric data allowed the determination of the kinetic parameters: activation energy (Ea), frequency factor (A), and reaction order (n). The thermal degradation of dapsone and topiramate was followed a first-order kinetic behavior. The calculated data evidenced a zero-order kinetic for dimethylsulfone. The relative thermal stabilities of the studied drugs have been evaluated and follow the order DDS > TOP > MSM. The purity was determined using DSC for the studied compounds, in drug substances and products. The results were in agreement with the recommended pharmacopoeia and manufacturer methods. DSC curves obtained from the tablets suggest compatibility between the drugs, excipients and/or coformulated drugs. The fragmentation pathway of dapsone with mass spectrometry was taken as example, to correlate the thermal decomposition with the resulted MS-EI. The decomposition modes were investigated, and the possible fragmentation pathways were suggested by mass spectrometry.
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MIYAKE, Masao, Mizuki HIRATA, Hiroaki OKAMOTO, and Tetsuji HIRATO. "Electrodeposition of Aluminum Using Dimethylsulfone-based Baths in Dry Air." Journal of The Surface Finishing Society of Japan 70, no. 10 (October 1, 2019): 523–27. http://dx.doi.org/10.4139/sfj.70.523.

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Dissertations / Theses on the topic "Dimethylsulfone"

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Borodina, Elena. "Bacterial metabolism of dimethylsulfone." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251998.

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Матрунчик, Ольга Леонідівна, Альона Геннадіївна Тульська, Світлана Германівна Дерібо, and Сергій Анатолійович Лещенко. "Анодні процеси в електрохімічному синтезі метансульфонової кислоти." Thesis, Дослідно-видавничий центр Наукового товариства ім. Т. Г. Шевченка, 2018. http://repository.kpi.kharkov.ua/handle/KhPI-Press/45473.

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Synthesis of methanesulfonic acid occurs during the course of an anode reaction – oxidation of dimethyl sulfoxide (DMSO). The application of the electrochemical method of oxidation DMSO allows you to control the process. The control parameters are: the potential of the anode, the catalytic activity of the anode material, the temperature of the electrolyte, promoters and inhibitors in the electrolyte. Voltamperic dependences of methanesulfonic acid from dilute solutions of DMSO with background with sulphate acid were contemplated. The emergence of a half-wave at cyclic voltammetric dependences and the dependence of its limiting current density on the concentration of DMSO indicates the occurrence of adsorption processes. We can talk about the process of oxidation of DMSO to methanesulfonic acid through the intermediate stage of the formation of dimethylsulphone. The possibility of electrochemical synthesis of methanesulfonic acid in a diaphragm electrolyzer with the ratio of the anode current density to the cathode 20:1 is shown.
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Boden, Rich. "Metabolism of dimethylsulfide in the bacteria." Thesis, University of Warwick, 2009. http://wrap.warwick.ac.uk/2741/.

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Dimethylsulfide (DMS) is a volatile organosulfur compound which has been implicated as playing key roles in climate control and in the biogeochemical cycling of sulfur. Metabolism of DMS by Bacteria has been previously identified as an important sink of DMS in soils and in the marine environment; however, relatively little is known about the physiology or biochemistry of Bacteria that metabolism DMS. The key enzyme of DMS oxidation in Hyphomicrobium spp. – DMS monooxygenase - has been purified and characterised from H. sulfonivorans. It has been shown to be a two-componant monooxygenase, related to bacterial luciferase, comprising two subunits – an FMNH2-dependent DMS monooxygenase (DmoA) and an NADHdependent FMN oxidoreductase (DmoB). For DMS, DMS monooxygenase from H. sulfonivorans has a Vmax of 1250 nmol DMS oxidised min-1 (mg protein)-1 and a kM of 16.5μM, corresponding to a kCAT of 5.2s-1. DMS oxidation in terms of acting as a sole-carbon source and as a supplementary energy source has been demonstrated in methylotrophic and heterotrophic bacteria. Chemolithoheterotrophic growth in which DMS carbon is assimilated to biomass whilst DMS sulfur is oxidised to tetrathionate with a net energy gain has been demonstrated in “M. thiooxidans”. Both “internal” and “external” chemolithoheterotrophy has been observed in “M. thiooxidans”, with endogenous and exogenous thiosulfate being oxidised to tetrathionate with a net energy gain. As far as can be found from the literature, this is the first recorded production of a polythionate from an organosulfur compound, as such, representing a potential new step in the biogeochemical sulfur cycle. Stable-isotope probing with [13C2]-DMS has been performed for the first time and has confirmed Methylophaga spp. as dominant DMS-oxidising Bacteria in the marine environment. The oxidation of marine thiosulfate to tetrathionate has been demonstrating during a phytoplankton bloom, indicating that chemolithoheterotrophic Bacteria are active during the bloom. Preliminary analyses have been carried out on the genome sequence of “Methylophaga thiooxidans” and the genes encoding the major enzymes of formaldehyde assimilation via the KDPG aldolase variant RuMP pathway have been identified. Genes encoding key enzymes involved in the dissimilation of methanol and methylated amines have been indentified, in addition to those involved in nitrogen uptake from ammonia, nitrate, nitrite and urea. Chemoorganoheterotrophic growth, coupling the oxidation of DMS to DMSO with ATP formation, has been demonstrated in Sagittula stellata E-37T, though the enzyme(s) responsible for this oxidation remain unclear.
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Heine, Christian Klaus. "NMR von rotatorischer und translatorischer Dynamik." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=96484916X.

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Bergeijk, Stefanie Anne van. "Production of dimethylsulfoniopropionate and dimethylsulfide in intertidal sediment ecosystems." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/83755.

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Shema, Richard A. "Correlation of satellite-detected aerosol characteristics and oceanic dimethylsulfide (DMS)." Thesis, Monterey, California. Naval Postgraduate School, 1988. http://hdl.handle.net/10945/22994.

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Eisman, Greg A. "Cloud reflectance characteristics in the presence of variable dimethylsulfide (DMS) sources." Thesis, Monterey, California. Naval Postgraduate School, 1989. http://hdl.handle.net/10945/26915.

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Lucas, Donald David 1969. "Mechanistic, sensitivity, and uncertainty studies of the atmospheric oxidation of dimethylsulfide." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/29759.

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Thesis (Ph. D. in Atmospheric Chemistry)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric, and Planetary Sciences, 2003.
Includes bibliographical references (p. 238-249).
The global-scale emissions and reactivity of dimethylsulfide (CH3SCH3, DMS) make it an integral component in the atmospheric sulfur cycle. DMS is rapidly oxidized in the atmosphere by a complex gas-phase mechanism involving many species and reactions. The resulting oxidized sulfur-bearing products are hygroscopic and interact with aerosols through condensation and secondary aerosol formation. Predictions of the impacts of DMS chemistry on aerosols and climate are inhibited by the poorly understood DMS oxidation mechanism. This thesis diagnoses the gas-phase connections between DMS and its oxidation products by simulating comprehensive DMS chemistry (approximately 50 reactions and 30 species) using three atmospheric models of varying size and complexity. A diurnally-varying box model of the DMS cycle in the remote marine boundary layer is used to identify important DMS-related parameters and propagate parameter uncertainties to the sulfur-containing species. This analysis shows that the concentrations of DMS and sulfur dioxide (SO2) are sensitive to relatively few parameters. Moreover, the concentrations of DMS and SO2 are found to have factor of 2 uncertainties caused primarily (more than 60% of the variance) by uncertainties in DMS emissions and heterogeneous removal, respectively. In contrast, the concentrations of other products, such as sulfuric acid (H2SO4) and methanesulfonic acid (CH3SO3H, MSA), are found to be sensitive to many parameters and have larger uncertainties (factors of 2 to 7) resulting from multiple uncertain chemical and non-photochemical processes. The DMS oxidation mechanism is quantitatively assessed using a one-dimensional column model constrained by high-frequency aircraft measurements from the
(cont.) First Aerosol Characterization Experiment (ACE-1). From this analysis, the baseline mechanism predicts DMS and SO2 concentrations in statistical agreement with the observations, yet it underestimates MSA concentrations by a factor of 10⁴ to 10⁵. These differences for MSA are statistically very significant and indicative of missing gas-phase reactions in the DMS mechanism. To reconcile these differences, five hypothetical MSA production paths are individually tested which greatly improve the model predictions to within a factor of 2 to 3 of the observations. Overall, the best improvement occurs when MSA is produced from the oxidation of methanesulfinic acid (CH3S(O)OH). Furthermore, the boundary layer model predictions of H2SO4 show improve ment after an SO2-independent sulfuric acid production channel is added to the mechanism. The DMS cycle is simulated in a global three-dimensional chemical transport model using, for the first time, comprehensive DMS oxidation chemistry. Four model cases are considered, which include two new comprehensive mechanisms and two parameterized schemes of 4 to 5 reactions taken from previous global sulfur models. The mole fractions of DMS, SO2, H2SO4, and MSA are compared between these four cases and with observations from the ACE-1 and PEM-Tropics A campaigns. Among the four cases, the calculated mole fractions of DMS and SO2 are largely invariant, while those for H2SO4 and MSA exhibit order-of-magnitude differences ...
by Donald David Lucas.
Ph.D.in Atmospheric Chemistry
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Ledyard, Kathleen Mei. "Marine microbial production of dimethylsulfide from dissolved dimethylsulfoniopropionate by Kathleen Mei Ledyard." Thesis, Massachusetts Institute of Technology, 1993. http://hdl.handle.net/1721.1/54359.

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Carnat, Gauthier. "Towards an understanding of the physical and biological controls on the cycling of dimethylsulfide (DMS) in Arctic and Antarctic sea ice." International Glaciological Society, 2013. http://hdl.handle.net/1993/23732.

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Little is known about the factors driving the cycle of the climate-active gas dimethylsulfide (DMS) and of its precursor the metabolite dimethylsulfoniopropionate (DMSP) in sea ice. To date, studies have focused on biotic factors, linking high DMSP concentrations to the high biomass of sympagic communities, and to physiological adaptations to the low temperatures and high salinities of the brine habitat. This thesis presents an approach integrating biotic and abiotic factors, investigating the influence of ice growth processes and brine dynamics on the DMS cycle. First, brine dynamics from growth to melt are explored based on ice temperature and salinity profiles measured in the Arctic. A strong but brief desalination phase is identified in spring. Using calculated proxies of permeability (brine volume fraction) and of the intensity of brine convection (Rayleigh number), this phase is shown to correspond to full-depth gravity drainage initiated by restored connectivity of brines on warming. Full-depth gravity drainage is crucial for the vertical transfer of DMS-compounds at the ice-ocean interface. This physical background is then used to investigate the spatio-temporal variability of DMS in Arctic sea ice during a year-round survey in Amundsen Gulf. The influence of processes such as scavenging and brine convection on the DMS cycle is shown, and the first combined measurement of DMS, DMSP, and dimethylsulfoxide (DMSO), a compound acting as source/sink for DMS through photo-chemical and bacterial processes, is presented. DMSO is shown to dominate the dimethylated sulfur pool in surface ice when the snow cover is low. Based on correlations with irradiance, it is suggested that this DMSO originates from photo-chemical oxidation of DMS trapped in impermeable ice. Finally, the spatio-temporal variability of DMS in Antarctic sea ice is investigated during another year-round survey in McMurdo Sound. Platelet crystals growth under the influence of ice-shelf waters are shown to favor the incorporation of strong DMSP producers, to increase the environmental stress on cells, and to favor the accumulation of DMS,P by reducing permeability. The increase of permeability on warming is shown to trigger strong release of DMS in the ocean and a vertical redistribution of DMSP in the ice cover.
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Books on the topic "Dimethylsulfone"

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Shema, Richard A. Correlation of satellite-detected aerosol characteristics and oceanic dimethylsulfide (DMS). Monterey, Calif: Naval Postgraduate School, 1988.

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Eisman, Greg A. Cloud reflectance characteristics in the presence of variable dimethylsulfide (DMS) sources. Monterey, Calif: Naval Postgraduate School, 1989.

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Ledyard, Kathleen Mei. Marine microbial production of dimethylsulfide from dissolved dimethylsulfoniopropionate / by Kathleen Mei Ledyard. Woods Hole : Woods Hole Oceanographic Institute, 1993.

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United States. National Aeronautics and Space Administration., ed. Dimethylsulfide oxidation over the tropical South Atlantic: OH and other oxidants. [Palo Alto, Calif.]: Dept. of Civil Engineering, Stanford University, 1994.

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United States. National Aeronautics and Space Administration., ed. Dimethylsulfide oxidation over the tropical South Atlantic: OH and other oxidants. [Palo Alto, Calif.]: Dept. of Civil Engineering, Stanford University, 1994.

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Book chapters on the topic "Dimethylsulfone"

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Vogt, M., and P. S. Liss. "Dimethylsulfide and climate." In Surface Ocean—Lower Atmosphere Processes, 197–232. Washington, D. C.: American Geophysical Union, 2009. http://dx.doi.org/10.1029/2008gm000790.

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Kappler, Ulrike, and Hendrik Schäfer. "Transformations of Dimethylsulfide." In The Metal-Driven Biogeochemistry of Gaseous Compounds in the Environment, 279–313. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9269-1_11.

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Andreae, M. O., and S. Rapsomanikis. "Dimethylsulfide Field Measurements." In Dimethylsulphide: Oceans, Atmosphere and Climate, 83. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-017-1261-3_9.

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Wohlfarth, Ch. "Dielectric constant of dimethylsulfide." In Supplement to IV/6, 152. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75506-7_60.

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Wohlfarth, Ch. "Dielectric constant of 2,4-dimethylsulfolane." In Supplement to IV/6, 356. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75506-7_200.

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Saltzman, Eric S. "Ocean/Atmosphere Cycling of Dimethylsulfide." In Ice Core Studies of Global Biogeochemical Cycles, 65–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-51172-1_4.

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Hansen, T. A., P. Quist, M. J. E. C. Van Der Maarel, and L. Dijkhuizen. "Isolation of Marine Dimethylsulfide-Oxidizing Bacteria." In Dimethylsulphide: Oceans, Atmosphere and Climate, 37–41. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-017-1261-3_5.

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McEwan, Alastair G., Tze-Hsien Toh, Peter S. Solomon, Anthony Shaw, and Stephen P. Hanlon. "Dimethylsulfide as an electron donor in Rhodobacter sulfidophilus." In Microbial Growth on C1 Compounds, 41–48. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0213-8_7.

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McTaggart, Andrew. "The Biogeochemistry of Dimethylsulfide in Antarctic Coastal Seawater." In Primary Productivity and Biogeochemical Cycles in the Sea, 521. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4899-0762-2_55.

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Wylie, D. J., M. J. Harvey, S. J. de Mora, I. S. Boyd, and J. B. Liley. "Dimethylsulfide and Aerosol Measurements at Ross Island, Antarctica." In Dimethylsulphide: Oceans, Atmosphere and Climate, 85–94. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-017-1261-3_10.

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Conference papers on the topic "Dimethylsulfone"

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Whitman, Jared, AnGayle Vasiliou, Daniel Anderson, Jessica Kong, and William Melhado. "MECHANISM OF THE THERMAL DECOMPOSITION OF ETHANETHIOL AND DIMETHYLSULFIDE." In 71st International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2016. http://dx.doi.org/10.15278/isms.2016.rf15.

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Zhao, Li, and Bo Qu. "Using Satellite Data to Calculate DimethylSulfide in Greenland Sea." In 2017 International Conference on Applied Mathematics, Modelling and Statistics Application (AMMSA 2017). Paris, France: Atlantis Press, 2017. http://dx.doi.org/10.2991/ammsa-17.2017.31.

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Ilyushin, V., Christof Maul, Sigurd Bauerecker, Laurent Manceron, Atef Jabri, F. Kwabia Tchana, R. Motiyenko, et al. "MICROWAVE AND FIR SPECTROSCOPY OF DIMETHYLSULFIDE IN THE GROUND, FIRST AND SECOND EXCITED TORSIONAL STATES." In 72nd International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2017. http://dx.doi.org/10.15278/isms.2017.ti03.

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Reports on the topic "Dimethylsulfone"

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Hynes, Anthony J. Kinetics, Mechanism and Product Yields in the Atmospheric Oxidation of Dimethylsulfide. Fort Belvoir, VA: Defense Technical Information Center, September 2000. http://dx.doi.org/10.21236/ada609849.

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Hynes, Anthony J. Kinetics, Mechanism And Product Yields In the Atmospheric Oxidation Of Dimethylsulfide. Fort Belvoir, VA: Defense Technical Information Center, September 1998. http://dx.doi.org/10.21236/ada539157.

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Hynes, Anthony J. Kinetics, Mechanism and Product Yields in the Atmospheric Oxidation of Dimethylsulfide. Fort Belvoir, VA: Defense Technical Information Center, September 2001. http://dx.doi.org/10.21236/ada628204.

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Hynes, Anthony J. Kinetics, Mechanism and Product Yields in the Atmospheric Oxidation of Dimethylsulfide. Fort Belvoir, VA: Defense Technical Information Center, September 1999. http://dx.doi.org/10.21236/ada631656.

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