Journal articles on the topic 'Dihydrofolate reductase'
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Wilquet, Valérie, Mark Van de Casteele, Daniel Gigot, Christianne Legrain, and Nicolas Glansdorff. "Dihydropteridine Reductase as an Alternative to Dihydrofolate Reductase for Synthesis of Tetrahydrofolate in Thermus thermophilus." Journal of Bacteriology 186, no. 2 (January 15, 2004): 351–55. http://dx.doi.org/10.1128/jb.186.2.351-355.2004.
Full textDedhar, S., D. Hartley, D. Fitz-Gibbons, G. Phillips, and J. H. Goldie. "Heterogeneity in the specific activity and methotrexate sensitivity of dihydrofolate reductase from blast cells of acute myelogenous leukemia patients." Journal of Clinical Oncology 3, no. 11 (November 1985): 1545–52. http://dx.doi.org/10.1200/jco.1985.3.11.1545.
Full textYoung, H. K., R. A. Skurray, and S. G. B. Amyes. "Plasmid-mediated trimethoprim-resistance in Staphylococcus aureus. Characterization of the first gram-positive plasmid dihydrofolate reductase (type S1)." Biochemical Journal 243, no. 1 (April 1, 1987): 309–12. http://dx.doi.org/10.1042/bj2430309.
Full textHammond, S. J., B. Birdsall, M. S. Searle, G. C. K. Roberts, and J. Feeney. "Dihydrofolate reductase." Journal of Molecular Biology 188, no. 1 (March 1986): 81–97. http://dx.doi.org/10.1016/0022-2836(86)90483-3.
Full textAdrian, P. V., and K. P. Klugman. "Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae." Antimicrobial Agents and Chemotherapy 41, no. 11 (November 1997): 2406–13. http://dx.doi.org/10.1128/aac.41.11.2406.
Full textAl-Rubeai, M., and J. W. Dale. "Purification and characterization of dihydrofolate reductase from Mycobacterium phlei." Biochemical Journal 235, no. 1 (April 1, 1986): 301–3. http://dx.doi.org/10.1042/bj2350301.
Full textStrehl, Elke, Ingrid Schneider, and Erich F. Elstner. "Inhibition of Dihydrofolate Reductase by Mofebutazon." Zeitschrift für Naturforschung C 48, no. 9-10 (October 1, 1993): 815–17. http://dx.doi.org/10.1515/znc-1993-9-1022.
Full textKehrenberg, Corinna, and Stefan Schwarz. "dfrA20, a Novel Trimethoprim Resistance Gene from Pasteurella multocida." Antimicrobial Agents and Chemotherapy 49, no. 1 (January 2005): 414–17. http://dx.doi.org/10.1128/aac.49.1.414-417.2005.
Full textFarnham, P. J., and R. T. Schimke. "Murine dihydrofolate reductase transcripts through the cell cycle." Molecular and Cellular Biology 6, no. 2 (February 1986): 365–71. http://dx.doi.org/10.1128/mcb.6.2.365-371.1986.
Full textFarnham, P. J., and R. T. Schimke. "Murine dihydrofolate reductase transcripts through the cell cycle." Molecular and Cellular Biology 6, no. 2 (February 1986): 365–71. http://dx.doi.org/10.1128/mcb.6.2.365.
Full textKadlec, Kristina, and Stefan Schwarz. "Identification of a Novel Trimethoprim Resistance Gene, dfrK, in a Methicillin-Resistant Staphylococcus aureus ST398 Strain and Its Physical Linkage to the Tetracycline Resistance Gene tet(L)." Antimicrobial Agents and Chemotherapy 53, no. 2 (November 17, 2008): 776–78. http://dx.doi.org/10.1128/aac.01128-08.
Full textRod, Thomas H., and Charles L. Brooks. "How Dihydrofolate Reductase Facilitates Protonation of Dihydrofolate." Journal of the American Chemical Society 125, no. 29 (July 2003): 8718–19. http://dx.doi.org/10.1021/ja035272r.
Full textFarnham, P. J., and R. T. Schimke. "In vitro transcription and delimitation of promoter elements of the murine dihydrofolate reductase gene." Molecular and Cellular Biology 6, no. 7 (July 1986): 2392–401. http://dx.doi.org/10.1128/mcb.6.7.2392-2401.1986.
Full textFarnham, P. J., and R. T. Schimke. "In vitro transcription and delimitation of promoter elements of the murine dihydrofolate reductase gene." Molecular and Cellular Biology 6, no. 7 (July 1986): 2392–401. http://dx.doi.org/10.1128/mcb.6.7.2392.
Full textAdrian, P. V., C. J. Thomson, K. P. Klugman, and S. G. B. Amyes. "Prevalence and genetic location of non-transferable trimethoprim resistant dihydrofolate reductase genes in South African commensal faecal isolates." Epidemiology and Infection 115, no. 2 (October 1995): 255–67. http://dx.doi.org/10.1017/s0950268800058386.
Full textMiller, A. D., M. F. Law, and I. M. Verma. "Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene." Molecular and Cellular Biology 5, no. 3 (March 1985): 431–37. http://dx.doi.org/10.1128/mcb.5.3.431-437.1985.
Full textMiller, A. D., M. F. Law, and I. M. Verma. "Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene." Molecular and Cellular Biology 5, no. 3 (March 1985): 431–37. http://dx.doi.org/10.1128/mcb.5.3.431.
Full textSutton, Cari, R. Scott McIvor, Micki Vagt, Barbara Doggett, and Raj P. Kapur. "Methotrexate-Resistant Form of Dihydrofolate Reductase Protects Transgenic Murine Embryos from Teratogenic Effects of Methotrexate." Pediatric and Developmental Pathology 1, no. 6 (November 1998): 503–12. http://dx.doi.org/10.1007/s100249900069.
Full textKLINGENBERG, Olav, and Sjur OLSNES. "Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin." Biochemical Journal 313, no. 2 (January 15, 1996): 647–53. http://dx.doi.org/10.1042/bj3130647.
Full textSchilling, L. J., and P. J. Farnham. "Identification of a new promoter upstream of the murine dihydrofolate reductase gene." Molecular and Cellular Biology 9, no. 10 (October 1989): 4568–70. http://dx.doi.org/10.1128/mcb.9.10.4568-4570.1989.
Full textSchilling, L. J., and P. J. Farnham. "Identification of a new promoter upstream of the murine dihydrofolate reductase gene." Molecular and Cellular Biology 9, no. 10 (October 1989): 4568–70. http://dx.doi.org/10.1128/mcb.9.10.4568.
Full textDuff, Michael R., Shaileja Chopra, Michael Brad Strader, Pratul K. Agarwal, and Elizabeth E. Howell. "Tales of Dihydrofolate Binding to R67 Dihydrofolate Reductase." Biochemistry 55, no. 1 (December 21, 2015): 133–45. http://dx.doi.org/10.1021/acs.biochem.5b00981.
Full textDeng, Hua, and Robert Callender. "Structure of Dihydrofolate When Bound to Dihydrofolate Reductase." Journal of the American Chemical Society 120, no. 31 (August 1998): 7730–37. http://dx.doi.org/10.1021/ja9814974.
Full textMatherly, LH, JW Taub, Y. Ravindranath, SA Proefke, SC Wong, P. Gimotty, S. Buck, JE Wright, and A. Rosowsky. "Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia." Blood 85, no. 2 (January 15, 1995): 500–509. http://dx.doi.org/10.1182/blood.v85.2.500.500.
Full textMatherly, LH, JW Taub, Y. Ravindranath, SA Proefke, SC Wong, P. Gimotty, S. Buck, JE Wright, and A. Rosowsky. "Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia." Blood 85, no. 2 (January 15, 1995): 500–509. http://dx.doi.org/10.1182/blood.v85.2.500.bloodjournal852500.
Full textVASUDEVAN, Subhash G., Bela PAAL, and Wilfred L. F. ARMAREGO. "Dihydropteridine Reductase fromEscherichia coliExhibits Dihydrofolate Reductase Activity." Biological Chemistry Hoppe-Seyler 373, no. 2 (January 1992): 1067–74. http://dx.doi.org/10.1515/bchm3.1992.373.2.1067.
Full textWU, Jia-Wei, Zhi-Xin WANG, and Jun-Mei ZHOU. "Inactivation kinetics of dihydrofolate reductase from Chinese hamster during urea denaturation." Biochemical Journal 324, no. 2 (June 1, 1997): 395–401. http://dx.doi.org/10.1042/bj3240395.
Full textDeng, Hua, Robert Callender, and Elizabeth Howell. "Vibrational Structure of Dihydrofolate Bound to R67 Dihydrofolate Reductase." Journal of Biological Chemistry 276, no. 52 (October 25, 2001): 48956–60. http://dx.doi.org/10.1074/jbc.m105107200.
Full textGiladi, Moshe, Neta Altman-Price, Itay Levin, Liat Levy, and Moshe Mevarech. "FolM, A New Chromosomally Encoded Dihydrofolate Reductase in Escherichia coli." Journal of Bacteriology 185, no. 23 (December 1, 2003): 7015–18. http://dx.doi.org/10.1128/jb.185.23.7015-7018.2003.
Full textMontoya-Zavala, M., and J. L. Hamlin. "Similar 150-kilobase DNA sequences are amplified in independently derived methotrexate-resistant Chinese hamster cells." Molecular and Cellular Biology 5, no. 4 (April 1985): 619–27. http://dx.doi.org/10.1128/mcb.5.4.619-627.1985.
Full textMontoya-Zavala, M., and J. L. Hamlin. "Similar 150-kilobase DNA sequences are amplified in independently derived methotrexate-resistant Chinese hamster cells." Molecular and Cellular Biology 5, no. 4 (April 1985): 619–27. http://dx.doi.org/10.1128/mcb.5.4.619.
Full textNavarro-Martínez, María Dolores, Enma Navarro-Perán, Juan Cabezas-Herrera, Joaquín Ruiz-Gómez, Francisco García-Cánovas, and José Neptuno Rodríguez-López. "Antifolate Activity of Epigallocatechin Gallate against Stenotrophomonas maltophilia." Antimicrobial Agents and Chemotherapy 49, no. 7 (July 2005): 2914–20. http://dx.doi.org/10.1128/aac.49.7.2914-2920.2005.
Full textTakahashi, H., M. Ozawa, C. Yamane, and M. Iwakura. "Mutation Analysis of Dihydrofolate Reductase." Seibutsu Butsuri 41, supplement (2001): S96. http://dx.doi.org/10.2142/biophys.41.s96_1.
Full textVillafranca, J. E., E. E. Howell, S. J. Oatley, M. S. Warren, C. David, J. Hirai, and J. Kraut. "Structures of engineered dihydrofolate reductase." Acta Crystallographica Section A Foundations of Crystallography 43, a1 (August 12, 1987): C320. http://dx.doi.org/10.1107/s0108767387076839.
Full textMünzel, Thomas, and Andreas Daiber. "Redox Regulation of Dihydrofolate Reductase." Arteriosclerosis, Thrombosis, and Vascular Biology 35, no. 11 (November 2015): 2261–62. http://dx.doi.org/10.1161/atvbaha.115.306556.
Full textMyllykallio, Hannu, Damien Leduc, Jonathan Filee, and Ursula Liebl. "Life without dihydrofolate reductase FolA." Trends in Microbiology 11, no. 5 (May 2003): 220–23. http://dx.doi.org/10.1016/s0966-842x(03)00101-x.
Full textBeard, W. A., J. R. Appleman, T. J. Delcamp, J. H. Freisheim, and R. L. Blakley. "Hydride Transfer by Dihydrofolate Reductase." Journal of Biological Chemistry 264, no. 16 (June 1989): 9391–99. http://dx.doi.org/10.1016/s0021-9258(18)60544-7.
Full textHitchings, George H. "Selective inhibitors of dihydrofolate reductase." In Vitro Cellular & Developmental Biology 25, no. 4 (April 1989): 303–10. http://dx.doi.org/10.1007/bf02624591.
Full textHamlin, Joyce L., and Chi Ma. "The mammalian dihydrofolate reductase locus." Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1087, no. 2 (October 1990): 107–25. http://dx.doi.org/10.1016/0167-4781(90)90195-8.
Full textHuennekens, F. M. "In search of dihydrofolate reductase." Protein Science 5, no. 6 (June 1996): 1201–8. http://dx.doi.org/10.1002/pro.5560050626.
Full textChu, Edward, Chris H. Takimoto, Donna Voeller, Jean L. Grem, and Carmen J. Allegra. "Specific binding of human dihydrofolate reductase protein to dihydrofolate reductase messenger RNA in vitro." Biochemistry 32, no. 18 (May 11, 1993): 4756–60. http://dx.doi.org/10.1021/bi00069a009.
Full textMeans, A. L., and P. J. Farnham. "Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site." Molecular and Cellular Biology 10, no. 2 (February 1990): 653–61. http://dx.doi.org/10.1128/mcb.10.2.653-661.1990.
Full textMeans, A. L., and P. J. Farnham. "Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site." Molecular and Cellular Biology 10, no. 2 (February 1990): 653–61. http://dx.doi.org/10.1128/mcb.10.2.653.
Full textBasco, Leonardo K., Rachida Tahar, and Pascal Ringwald. "Molecular Basis of In Vivo Resistance to Sulfadoxine-Pyrimethamine in African Adult Patients Infected withPlasmodium falciparum Malaria Parasites." Antimicrobial Agents and Chemotherapy 42, no. 7 (July 1, 1998): 1811–14. http://dx.doi.org/10.1128/aac.42.7.1811.
Full textWU, Jia-Wei, and Zhi-Xin WANG. "Activation mechanism and modification kinetics of Chinese hamster dihydrofolate reductase by p-chloromercuribenzoate." Biochemical Journal 335, no. 1 (October 1, 1998): 181–89. http://dx.doi.org/10.1042/bj3350181.
Full textCody, Vivian, Qilong Mao, and Sherry F. Queener. "Recombinant bovine dihydrofolate reductase produced by mutagenesis and nested PCR of murine dihydrofolate reductase cDNA." Protein Expression and Purification 62, no. 1 (November 2008): 104–10. http://dx.doi.org/10.1016/j.pep.2008.07.001.
Full textXu, Ying, Georges Feller, Charles Gerday, and Nicolas Glansdorff. "Moritella Cold-Active Dihydrofolate Reductase: Are There Natural Limits to Optimization of Catalytic Efficiency at Low Temperature?" Journal of Bacteriology 185, no. 18 (September 15, 2003): 5519–26. http://dx.doi.org/10.1128/jb.185.18.5519-5526.2003.
Full textHerrington, Muriel B., and Neema T. Chirwa. "Growth properties of afolAnull mutant ofEscherichia coliK12." Canadian Journal of Microbiology 45, no. 3 (March 1, 1999): 191–200. http://dx.doi.org/10.1139/w98-229.
Full textKatayanagi, K., Y. Kamiya, T. Sato, E. Ohmae, and K. Gekko. "Crystal structure of dihydrofolate reductase mutants." Seibutsu Butsuri 40, supplement (2000): S122. http://dx.doi.org/10.2142/biophys.40.s122_1.
Full textIQBAL, M. PERWAIZ, N. MEHBOOBALI, M. ANWAR WAQAR, and HINA S. ZUBERI. "Dihydrofolate reductase from a reptile, uromastix." Biochemical Society Transactions 19, no. 2 (April 1, 1991): 193S. http://dx.doi.org/10.1042/bst019193s.
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