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Journal articles on the topic 'Digestive morbidity'
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Miridzhanyan, G. M., and Nataliya V. Polunina. "THE DYNAMICS OF PREVALENCE OF DISEASES OF DIGESTIVE ORGANS IN POPULATION OF THE REPUBLIC OF ARMENIA." Medical Journal of the Russian Federation 23, no. 4 (August 15, 2017): 172–74. http://dx.doi.org/10.18821/0869-2106-2017-23-4-172-174.
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The article presents the results of analysis of morbidity of diseases of digestive organs шт the Republic of Armenia. It is established that in the Republic of Armenia during 1990-2015 primary morbidity of diseases of digestive organs in children population reliably increased up to 2.4 times and in adult population - up to 1.9 times. The leading diseases in the structure of primary morbidity among children population is gastroduodenitis (39.7%) and among adult population - gastritis (54.6%). In the Republic, the indices of total morbidity of diseases of digestive organs during the same period of time increased reliably from 57,5‰ to 100,3‰ in children population and from 50,9‰ to 60,2‰ adult population. At the same time, during last 15 years at stabilization of level of morbidity with temporary disability average duration of one case of disease with temporary disability up to 11.6% and primary disability up to 2.9%.
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Ibraeva, L. K., A. U. Amanbekova, N. M. Zhanbasinova, L. Sh Sexenova, D. H. Rybalkina, B. M. Salimbayeva, E. A. Drobchenko, and A. O. Gazizova. "Epidemiological aspects of morbidity in the class of digestive organs in Kazakhstan." Terapevticheskii arkhiv 90, no. 2 (February 15, 2018): 75–78. http://dx.doi.org/10.26442/terarkh201890275-78.
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Aim. To study epidemiological aspects of disease, class of diseases of the digestive system in the region of the relative risk in Kazakhstan. Materials and methods. Studied epidemiological parameters are first identified in the incidence and prevalence of class XI ICD in regions of Kazakhstan with the identification of risk relative to the average national level. In a dysfunctional region Kyzylorda region analyzed the performance of its regions and compared with data from medical examination of the population and the survey. Results. A significant excess of the average national incidence rate between 1990 and 2015, was noted for 3 of the 14 regions of Kazakhstan (West-Kazakhstan, Kyzylorda, Mangystau). According to the dynamics of the unfavorable situation on the high level of incidence currently is in the Kyzylorda region (COA). From the areas of the COA maximum, the incidence of diseases of the digestive system registered in Kazalinsk district which exceeded the level at RK 4.8 times. The data on examination and survey of the complaints of the population exceeded the epidemiological indicators. In the area identified as the leading neoplasms of the digestive system in the structure of cancer incidence and exceeded the national average on the related class of blood diseases. Unfavorable situation on the incidence of the digestive system in Kyzylorda region of Kazakhstan is associated with the cancer and blood diseases, this is partly due to the presence of pollutants in the environment.
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Gofti-Laroche, L., B. Gratacap-Cavallier, D. Demanse, O. Genoulaz, J. M. Seigneurin, and D. Zmirou. "Are waterborne astrovirus implicated in acute digestive morbidity (E.MI.R.A. study)?" Journal of Clinical Virology 27, no. 1 (May 2003): 74–82. http://dx.doi.org/10.1016/s1386-6532(02)00130-0.
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Rommel, Nathalie, Jan Tack, Jan Deprest, Karel Allegaert, and Maissa Rayyan. "Esophageal Atresia: Future Directions for Research on the Digestive Tract." European Journal of Pediatric Surgery 27, no. 04 (August 17, 2016): 306–12. http://dx.doi.org/10.1055/s-0036-1587330.
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AbstractEsophageal atresia (EA) is a congenital malformation defined by the discontinuity of the esophagus occurring in 2.4 in 10,000 births. As survival rates are high, the significant medical morbidity became more relevant. Short-term and long-term morbidities involve the respiratory and gastrointestinal system in the majority of the patients. The impact of this morbidity seems large enough to inspire researchers to develop experimental animal models that may help understanding the pathogenesis and pathophysiology. These models can also be used to explore potential surgical therapies. We reviewed the clinical and experimental literature focusing on esophageal morbidity in EA. Although the consequences of esophageal motility disorders are very relevant in the clinical setting, research remains largely underexplored. Consequently, we suggest integrating motility function assessment in the existing research models.
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DePaula, Aureo L., Antonio L. V. Macedo, Claudio R. Cernea, Vladimir Schraibman, Jacques Pinus, José R. Milanez, José E. Succi, Flávio C. Hojaij, Dorival de Carlucci, and Sunao Nishio. "Reconstruction of upper digestive tract: Reducing morbidity by laparoscopic pull-up." Otolaryngology–Head and Neck Surgery 135, no. 5 (November 2006): 710–13. http://dx.doi.org/10.1016/j.otohns.2006.04.019.
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Umarova, D. N., and E. R. Pogrebnichenko. "ANALYSIS OF MORBIDITY OF CHILD POPULATION OF ASTRAKHAN." Chronos 6, no. 7(57) (July 13, 2021): 10–12. http://dx.doi.org/10.52013/2658-7556-57-7-4.
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One of the indicators of population health is morbidity. In recent years, there has been a steady increase in the incidence rate of children in the Russian Federation, an increase in chronic and concomitant diseases, an increase in the number of disabled children. The article presents indicators of the level and structure of the incidence of children. The analysis of incidence rates allows us to say that in 2019. the first place is occupied by diseases of the digestive system, the second place is taken by the nervous system and the third place is taken by the musculoskeletal system.
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Borayeva, T. T., and O. V. Remizov. "Dynamics of Morbidity in Children with Pathology of the Upper Digestive Tract." Effective Pharmacotherapy 15, no. 21 (June 14, 2019): 12–16. http://dx.doi.org/10.33978/2307-3586-2019-15-21-12-16.
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Mukhanova, Gulzhan, Madina Ospanaliyeva, Madina Kamaliyeva, Balzhan Duisenbayeva, Rauza Kenzhekulova, and Laura Sakhanova. "Incidence of Morbidity Among Children and Adolescents in Kazakhstan." Journal of Health Development 1, no. 45 (2022): 36–46. http://dx.doi.org/10.32921/2225-9929-2022-1-45-36-46.
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Purpose of the research: To study the dynamics of changes in the structure of morbidity among children in Kazakhstan for 2018-2020.Methods: The comparative analysis of the data of the annual form «Report on the number of diseases registered in patients living in the service area of a medical organization and patients' groups under the clinical supervision» for 2018-2020 has been conducted. Results. According to the results of 2020 data analysis in Kazakhstan, the number of registered diseases among children aged 0-14 and adolescents aged 15-17 decreased by 7% compared to 2018. Respiratory diseases in the 0-14 age group accounted for 51,8 per cent of all reported cases. Among adolescents aged 15-17, respiratory illnesses accounted for 33,81 per cent. Digestive diseases are second in the 0-14 age group, accounting for 9,2 per cent and 10,65 per cent for adolescents. Nervous system diseases in children from 0 to 14 years of age accounted for 6 per cent and for the treatment in third place. Among 15-17-year-olds, the third place is occupied by eye disease and its appendage apparatus, which accounted for 10,35 per cent.Conclusions. Analysis of the obtained data showed that the morbidity rate among children and adolescents for 2018-2020. has a tendency to decrease. The most common diseases among children are diseases of the respiratory system, diseases of the digestive system, diseases of the eye and appendage apparatus, diseases of the nervous system. At the same time, there has been an increase in the number of diseases of the nervous system
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Urusova, M. A. "PRIMARY MORBIDITY AND DISABILITY OF THE ADULT POPULATION DUE TO PANCREATIC DISEASES IN THE BELGOROD REGION IN DYNAMICS FOR 2011–2018." Bulletin of the Russian association of specialists in medical and social expert evaluation, rehabilitation and rehabilitation industry 3 (2020): 65–75. http://dx.doi.org/10.17238/issn1999-2351.2020.3.65-75.
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The analysis of indicators of primary disability due to diseases of pancreas among adult population of the Belgorod region during 8 years. Rank places of diseases of digestive organs in structure of morbidity and primary disability were defined. The revealed main features and trends of morbidity and disability, were investigated to further optimization of medico-social service and improved support to this contingent of disabled people
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Gidenne, T., L. Mirabito, N. Jehl, J. M. Perez, P. Arveux, A. Bourdillon, C. Briens, J. Duperray, and E. Corrent. "Impact of replacing starch by digestible fibre, at two levels of lignocellulose, on digestion, growth and digestive health of the rabbit." Animal Science 78, no. 3 (June 2004): 389–98. http://dx.doi.org/10.1017/s1357729800058793.
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AbstractFour diets were arranged using a 2 ✕ 2 factorial design with two levels of lignocellulose, a high ‘HF’ or a low level ‘LF’ (acid-detergent fibre (ADF) = 191 v. 155 g/kg), combined with two levels of starch replacing 50 g/kg of digestible fibre (DF = hemicelluloses + pectins), a high starch (low DF) ‘HS’ or a low starch (high DF) level ‘LS’ (starch = 193 v. 123 g/kg). Two trials were conducted to measure digestive efficiency and rate of passage, respectively. A third trial was performed in a network of six French experimental breeding units to measure growth and digestive health on 507 rabbits per diet. Foods were offered ad libitum from weaning to slaughter.No significant interactions were detected between the effect of the level of lignocellulose and the effect of starch replacement by DF, on rabbit digestion, performance or digestive health. A proportional increase of overall food digestibility (organic matter (OM) or energy) was observed with the decrease of ADF level. When 50 g/kg of DF was replaced by starch we observed a significant improvement of OM and energy digestibility ( + 0·03 units). The whole-tract mean retention time of particles was 21 h. It was significantly longer with a lower ADF level ( + 5·4 h for LF v. HF diets), and it tended to increase when DF was substituted by starch ( + 2·2 h for HS v. LS diets).Between weaning and slaughter, food intake was mainly affected by the ADF level (139 v. 130 g/day respectively for HF and LF diets) and to a lesser extent by the replacement of DF by starch (136·2 v. 133·4 g/day, respectively for LS and HS diets). The weight gain was only slightly higher for high starch (low DF) diets ( +1 g/day) without an effect of the ADF level.Between weaning and slaughter, morbidity and mortality rates (from acute diarrhoea) were significantly reduced with high-fibre diets (-6 and -4 units respectively), while the replacement of DF by starch had no significant effect.
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Bacalbasa, Nicolae, Olivia Ionescu, Paris Ionescu, and Irina Balescu. "Digestive resections in advanced-stage ovarian cancer." Advances in Modern Oncology Research 2, no. 3 (June 16, 2016): 132. http://dx.doi.org/10.18282/amor.v2.i3.87.
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The standard frontline treatment for advanced-stage ovarian cancer (ASOC) consists of maximal cytoreduction surgery associated with platinum/paclitaxel-based chemotherapy. Several studies have proven that patients with no gross residual disease (RD) have better survival rates than those with optimal but visible RD (RD ≤1 cm). In order to achieve this, more radical cytoreductive procedures such as radical pelvic resection and extensive upper abdominal procedures are performed. However, some investigators have suggested that, although effective, radical surgery cannot fully compensate tumor biology, which is a major determinant in survival and in turn influences the likelihood of surgical cytoreduction. The aim of this review was to present the procedures defining ultra-radical (extensive) surgery and to evaluate its feasibility and morbidity in the management of ASOC.
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Daneshpouy, Marjan, Gerard Socie, Marc Lemann, Jacqueline Rivet, Eliane Gluckman, and Anne Janin. "Activated eosinophils in upper gastrointestinal tract of patients with graft-versus-host disease." Blood 99, no. 8 (April 15, 2002): 3033–40. http://dx.doi.org/10.1182/blood.v99.8.3033.
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Abstract Digestive tract damage during graft-versus-host reaction (GVHR) causes high morbidity and mortality. Diagnosis is often late because biopsies are performed when clinical signs are severe and pathologic markers of early inflammatory lesions are lacking. Eosinophils are inflammatory cells, cytotoxic in vitro to digestive epithelium; they are found in biopsy specimens taken during acute flare-ups of inflammatory bowel disease. We performed systematic duodenal biopsies immediately after digestive symptoms occurred and found a digestive GVHR incidence of 73.1% (n = 93), higher than that found when digestive biopsies were performed immediately after severe clinical signs. Eosinophils were only present when there were histologic signs of GVHR; eosinophil presence correlated with GVHR severity. Electron microscopy with immunogold staining showed pathologic signs of in situ eosinophil activation, such as cytoplasmic granule alterations, and eosinophil peroxidase release in all patients. Interleukin-5 presence in activated eosinophils suggests eosinophil recruitment in digestive GVHR is an autocrine mechanism. Eosinophil density also correlated with GVHR severity, whether in acute or chronic clinical phases. Tissue eosinophils could thus be a marker of acute inflammatory flare-ups in GVHR. Systematic duodenal biopsy performed at the onset of digestive symptoms should allow early GVHR detection, and pathologic signs of GVHR, together with eosinophil density, might help modulate immunosuppressive therapy.
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Сапожников, Vladimir Sapozhnikov, Воробьева, and A. Vorobeva. "The objective criteria of chronic diseases of digestive system in children (literature review)." Journal of New Medical Technologies. eJournal 9, no. 1 (April 17, 2015): 0. http://dx.doi.org/10.12737/7593.
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Recently, in Russia the number of children with chronic inflammatory diseases of the digestive system grows steadily. Chronic diseases of the digestive system in children often begin in pre-school and school age. This article discusses the objective criteria of the chronic diseases of the digestive system in children. This pathology is an important social and medical problem among children. Today, there are many children with digestive pathology. The leading is gastro-duodenal pathology. Analysis of the above data shows the high complexity of the diagnostic evaluation of different symptoms that can only be detected on palpation of the anterior abdominal wall in children with combined pathology of the organs of the gastro-duodenal zone. This is due to the co-morbidity of development of pathological process. On the other part, however, the authors observed a logical relation in the frequency of occurrence of these or other symptoms depending on the extent and nature of the lesion of the stomach, duodenum, biliary system, pancreas in children. This again underlines the importance of improving instrumental methods in children with disorders of the digestive system.
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Baranovsky, Andrey Yu, Alexey M. Belyaev, and Elina A. Kondrashina. "Morbidity and Mortality Rates from Digestive Diseases in the RF Northwestern Federal District (NWFD) and Measures to Reduce Them." Russian Journal of Gastroenterology, Hepatology, Coloproctology 29, no. 1 (March 31, 2019): 36–46. http://dx.doi.org/10.22416/1382-4376-2019-29-1-36-46.
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Aim: to analyze the dynamics of morbidity and mortality from digestive diseases, as well as their causes, in the RF Northwestern Federal District (NWFD).Materials and methods. A statistical analysis was carried out on the basis of the 2007–2017 annual reports of the Medical Information and Analytical Center (MIAC) in St. Petersburg and the reports of the chief gastroenterologists of the Northwestern Federal District subjects.Results. In the RF Northwestern Federal District, an increase in both morbidity and mortality from digestive diseases is observed. The main non-oncological reasons for the development of these disorders include alcoholic liver disease, chronic alcoholic pancreatitis, peptic ulcer complications and NSAID-associated gastropathies. Along with a decrease in the incidence of gastric cancer, an increase in the incidence of colorectal cancer, as well as pancreatic cancer, is observed. A decrease in mortality from all the aforementioned cancer localizations is revealed.Conclusions. The main reasons for the increase in morbidity and mortality due to gastroenterological diseases in the RF Northwestern Federal District include alcohol abuse among the population, inadequate prevention of gastric helicobacteriosis, insufficient expertise of physicians in terms of Helicobacter pylorieradication and cancer prevention.
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Rzayeva, A. J. "Comprehensive assessment of morbidity, temporary and permanent disability, mortality of railwaymen." Kazan medical journal 97, no. 4 (August 15, 2016): 624–29. http://dx.doi.org/10.17750/kmj2015-624.
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Aim. To study morbidity, temporary and permanent disability and mortality among railway workers.Methods. The incidence and overall morbidity was studied based on information about the final diagnosis in statistical coupons and outpatient medical records by continuous coverage for the period of 2005-2014. Based on the analysis of the documents of all persons who underwent examination in the medical and social commissions for the period of 2007-2012, the primary disability was investigated. Temporary disability was analyzed for the period of 2006-2014 using all sick leaves, provided for payment in the accounting department of the railway system. Analysis of the mortality rate and causes of death was conducted by the continuous study of the medical certificates of cause of death for 2005-2010. We analyzed 336 death certificates, as well as the appropriate number of outpatient medical records and case histories.Results. Among the overall morbidity, the leading place belongs to the digestive system diseases with the variations in morbidity rates from 259.4±2.1‰ to 299.5±2.4‰. Among the disability causes of railway workers, diseases of the cardiovascular system are on the leading place, which accounted for 50.2±3.2% of all cases of primary disability. Total mortality rate varied from 2.35±0.29‰ (2008) up to 1.58±0.24‰ (2010).Conclusion. In the structure of disease incidence of railway workers digestive system diseases prevail, it distinguishes this contingent from the Azerbaijan working age population, which is characterized by the predominance of respiratory diseases; disability rate is higher in women than in men (68.0±20.4 and 32.1±6.8 to 10 thousand respectively).
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Rakhmanov, Rofail, Elena Bogomolova, Sergey Razgulin, Gamzat Bakhmudov, Murat Alikberov, Sergey Zhargalov, and Dmitriy Nepryakhin. "Analysis of dental morbidity of persons of an organized team in unfavorable working conditions." Sanitarnyj vrač (Sanitary Inspector), no. 4 (April 1, 2020): 49–56. http://dx.doi.org/10.33920/med-08-2004-06.
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The prevalence of diseases of the oral cavity in military personnel serving under the contract at various altitudes above sea level in Dagestan was estimated. The working conditions and the influence of physical environmental factors at the effective temperature in the autumn-winter-spring periods of the year are estimated. Professional activity belonged to the category of works IIb. Labor was assessed as harmful 2 degrees (class 3.2). In the winter season, a critical risk of frostbite of the body at medium temperatures and maximum wind was found at heights of 4 m and 1661 m. In the spring and autumn, a moderate risk of frostbite was noted at all altitudes. Dental diseases were registered in the classes «Neoplasms», «Diseases of the digestive system» and «Injuries and poisoning»; their share in the total structure was 15.03%. In the class «Diseases of the digestive system,» the share of dental diseases reached 80.2%. The group «Caries, its complications and other diseases of hard tissues of teeth» occupied the 1st rank place in the structure of morbidity, which is equal to morbidity in the class «Respiratory diseases». The level of oral hygiene is 2.8 ± 0.2 (very low): the teeth are significantly covered with plaque, leading to the progression of pathological processes. Description of the dental status: KPU index (carious, filled, extracted tooth) is 8.5 ± 0.3. The prevailing indicator was «carious», indicating an active carious process in the tissues of the teeth and the «lag» of the treatment, leading to their removal. Military personnel approached a critical indicator of fitness for professional activity. The need for oral sanitation reached 65.5 ± 7.9%. The share of labor losses for dental diseases of the class «Digestive apparatus diseases» reached 3.2%, excluding separation from duty on the day of treatment, of which there are several. The study proves the impact of adverse working conditions on dental morbidity, the need for their assessment to identify risk factors and develop preventive measures.
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Egorova, Alla, Andrey Orlov, and Sergey Suslin. "Justification of regional programs for the control and prevention of malignant neoplasms of the digestive system based on an international comparison of morbidity, mortality and survival rates (research based on materials from CI5 and Concord 3)." Problems in oncology 67, no. 1 (March 4, 2021): 51–58. http://dx.doi.org/10.37469/0507-3758-2021-67-1-51-58.
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In the Russian Federation, in comparison with the average European indicators, mortality with malignant neoplasm of the digestive system, even against the background of low morbidity, remains high. For the scientific substantiation and detailing of organizational measures to improve the control and prevention programs for malignant neoplasm of the digestive system, currently being carried out within the framework of the national project "Fight against cancer in 2019-2024", using the example of one of the typical regions of the Russian Federation - the Samara region, an international assessment was carried out the quality of medical care for this group of patients. At the same time, data on patients included in the database of the Samara population cancer registry in the period 2003-2017, data on cancer patients in the Samara region for the period 2008-2012, included in Cancer Incidence in Five Continents Vol.XI, as well as data on patients with malignant neoplasms registered in the Samara region in 2010-2014 and included in the Concord 3 study. The quality of medical care was assessed for all localizations of the digestive system based on the analysis of trends in morbidity, mortality and relative survival rates. An international study has shown that in the Samara region, in comparison with European countries, practically in all malignant neoplasms of the digestive system, with a low morbidity, high mortality and low survival are noted. Based on the data of a reliable onco-epidemiological study carried out in accordance with international standards, it was found that in the regions of the Russian Federation, when developing the financial, human and organizational resources of the national project to combat malignant neoplasms, special attention should be paid to primary prevention programs for colon cancer, liver cancer and gallbladder; organization of comprehensive colorectal cancer screening programs; as well as active implementation of programs for early diagnosis and effective treatment of stomach, pancreas, liver, esophagus and gallbladder cancer.
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AITMAGANBET, Perizat, Gulmira UMAROVA, Valentina SABYRAKHMETOVA, Sergey PEREPELKIN, Dariya DOSKABULOVA, Gulnur URGUSHBAEVA, and Dina EGIZBAEVA. "Influence of Atmospheric Air Quality on the Morbidity of the Population Living in the Region of Oil and Gas Production in the Republic of Kazakhstan." Journal of Environmental Management and Tourism 11, no. 3 (June 12, 2020): 563. http://dx.doi.org/10.14505//jemt.v11.3(43).08.
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Sarkuland Kenkiyak settlements are located in the Aktobe province, at18-20 km from the oil and gas producing field "Zhanazhol", in the northwest region of the Republic of Kazakhstan. To evaluate the exposure of the adult male and female population living in Sarkul and Kenkiyak settlements, a single medical study was conducted. The nonparametric method of the Spearman correlation analysis was performed between the mean concentration of substances exceeding the Maximum Permissible Concentration and the classes of newly diagnosed diseases. Selection and analysis of air samples was carried out according to the developed research protocol; the qualitative-quantitative analysis was carried out on the Gas analyzer HANK-4 apparatus. Significant pollution of atmospheric air by carbon monoxide, benzapyrene, dust and phenol were identified in places. Correlation dependencies between these pollutants of air and the diseases of the population revealed as a result of medical examination are established, as a result of diseases of the circulatory system, ear and mastoid process, nervous system and digestive organs; between the concentration of carbon monoxide and diseases of the circulatory system, the digestive system, the genitourinary system and the musculoskeletal system; between nitric oxide and diseases of the digestive system and the circulatory system; between benzopyrene and diseases of the digestive system, the genitourinary system and the nervous system.
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Gofti-Laroche, L., B. Gratacap-Cavallier, O. Genoulaz, J. C. Joret, Ph Hartemann, J. M. Seigneurin, and D. Zmirou. "A new analytical tool to assess health risks associated with the virological quality of drinking water (EMIRA study)." Water Science and Technology 43, no. 12 (June 1, 2001): 39–48. http://dx.doi.org/10.2166/wst.2001.0709.
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This work assessed the risks associated with the virological quality of tapwater using a molecular analytical tool manageable in a field survey. It combined a daily epidemiological follow-up of digestive morbidity among a panel of volunteers and a microbiological surveillance of drinking water. RT-PCR was used for detection of enterovirus, rotavirus and astrovirus. 712 cases of acute digestive conditions occurred in the 544 volunteers. 38% (9/24) raw water and 23% (10/44) tap water samples were positive for at least one virus marker with 9/10 positive tap water samples complying with bacterial criteria. No statistically significant association was found between the presence of viral markers and observed incidence of digestive morbidity. However, when an outbreak occurred, enterovirus and rotavirus RNA was detected in the corresponding stored tap water samples. Sequencing of the amplified fragments showed that the rotavirus detected was of bovine origin. This work demonstrated that enteric virus markers were common in tapwater of the study communities (characterised by a vulnerable raw water) despite absence of bacterial indicators. Tangential ultrafiltration coupled to RT-PCR allowed a simultaneous and fast detection of the study viruses from environmental samples. This process is a promising tool usable for virological water surveillance, in as much the corresponding know-how is transferred to the field professionals.
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Hentati, Hassen, Chady Salloum, Philippe Caillet, Eylon Lahat, Mara Disabato, Eric Levesque, Philippe Compagnon, Chetana Lim, and Daniel Azoulay. "Risk Factors for Mortality and Morbidity in Elderly Patients Presenting with Digestive Surgical Emergencies." World Journal of Surgery 42, no. 7 (December 30, 2017): 1988–96. http://dx.doi.org/10.1007/s00268-017-4419-3.
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Boom, S. J., and G. Ramsay. "Selective decontamination of the digestive tract in intensive care." Epidemiology and Infection 109, no. 3 (December 1992): 337–47. http://dx.doi.org/10.1017/s0950268800050330.
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SUMMARYNosocomial infection in intensive care unit (ICU) practice is a common problem and is associated with abnormal carriage of Gram-negative aerobic bacilli in the gastrointestinal tract, resulting in endogenous infections. Selective decontamination of the digestive tract (SDD) is a regimen aimed at preventing or eradicating this abnormal carriage.A large number of trials examining SDD in ICU practice have been published, the vast majority showing a significant reduction in the incidence of nosocomial, Gram-negative infection. However, the impact on morbidity and mortality is much less certain. A recent meta-analysis has suggested a 10–20% reduction in mortality (3–6% absolute difference) with SDD. A discussion of these results is presented together with potential criticisms of SDD.
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Mancini, Simone, and Gisella Paci. "Probiotics in Rabbit Farming: Growth Performance, Health Status, and Meat Quality." Animals 11, no. 12 (November 26, 2021): 3388. http://dx.doi.org/10.3390/ani11123388.
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The rabbit’s complex microbiota of the gastrointestinal tract (GIT) plays a critical role in feed digestion, in vitamin production, in fermentative activity with production of volatile fatty acids, and stimulation of immune response, as well as in the infection defence against pathogens and countering environmental stresses. To prevent digestive disorders of this fragile ecosystem, rabbit breeders adopt suitable diets supplemented with additives such as probiotics. Probiotics can interact with the host and with the other microflora leading to an increased health status. A review on the effects of probiotics on rabbit growth performance, health status, and meat quality was conducted to reduce the incidence of digestive diseases and enhance productive performance. Some authors observed that the supplementation of probiotics to the diet improved feed conversion ratio and growth and digestion coefficients, while other authors reported a lack of effect on the live performance. Benefits derived from the use of probiotics were observed on the mortality and the morbidity. The studies performed, to evaluate the effects of probiotic supplementation in diets on the immune response, showed variations in the results. Some authors reported no significant effect on haematological parameters, such as total protein, immunoglobulins, and IgG, while others observed a significant increase or decrease of the same parameters. Most of the research reported significant modifications of intestinal morphology and positive effects on the GIT microbiota, supporting the host’s natural defences. Regarding the carcass and meat quality, the studies reported only partial and opposing results.
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Ivanova, Inna Leonidovna, Antonina Anatolievna Vazhenina, Lidiya Viktorovna Trankovskaya, and Elena Borisovna Anishchenko. "Some features of the digestive system incidence of children population off the Primorsky Territory." Sanitarnyj vrač (Sanitary Doctor), no. 12 (December 1, 2020): 54–61. http://dx.doi.org/10.33920/med-08-2012-07.
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The article presents the results of a hygienic study conducted in the territory of the Primorsky Territory to assess the primary incidence of digestive system organs among the children of the Primorsky Territory. For the study, data on the recorded primary incidence for 18 years were analyzed. Mapping of the primary morbidity was carried out, the attributive risk of digestive diseases was calculated. The territorial distribution of statistically significant average annual levels of primary morbidity showed that children are more likely to suffer from gastritis and duodenitis, gastric ulcer and duodenal ulcer in the northern part of the region, where the highest incidence rates are recorded — these are rural areas. with an unstable economic situation and areas of the eastern coast of Primorye with the most unfavorable climatic conditions. The results of calculating the attributive risk show that children (0–7 years old) living in rural areas of the Primorsky Territory belong to the risk group for diseases of the digestive system. The identified territories are the least economically developed, with the absence of powerful sources of anthropogenic pollution of the population's habitat. The results obtained in this work should be taken into account when choosing and substantiating the indicators of the regional information fund for social and hygienic monitoring, when developing effective primary prevention measures and making managerial decisions at the regional level in the field of health care for children and children. adolescents in the Primorsky Territory.
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Bhattacharyya, B. K., S. Chowdhury, S. Das, S. Mukherjee, and D. Bhattacharjee. "Treatment of Pancreatic Exocrine Insufficiency with Enteric Coated Pancreatin Formulations: An Overview." International Journal of Pharmaceutical Sciences and Nanotechnology 6, no. 3 (November 30, 2013): 2125–30. http://dx.doi.org/10.37285/ijpsn.2013.6.3.3.
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Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease. It is used to treat conditions in which pancreatic secretions are deficient, such as surgical pancreatectomy, pancreatitis and cystic fibrosis. Pancreatin products contain the pancreatic enzymes trypsin, amylase and lipase. The patients with pancreatic diseases often suffer from pancreatic exocrine insufficiency. In such condition pancreas does not secrete required amount of digestive enzymes for proper digestion to occur. Severe pancreatic insufficiency occurs in cystic fibrosis, chronic pancreatitis, tumors or after surgical resection. Thus pancreatic exocrine insufficiency may result in clinical manifestation of malnutrition, weight loss and steatorrhea leading towards the increased risk of morbidity and mortality. For the improvement of clinical symptoms, restriction of fat intake and pancreatic enzyme replacement therapy are recommended. The enzyme substitution therapy is very much challenging because the optimal enzyme dose is highly variable to mimic the physiological pattern of pancreatic exocrine secretion. Regulatory authorities have approved several pancreatic enzyme formulations in the form of enteric coated minimicrosphere which are now available commercially. This review focuses on the physiological considerations of pancreatic exocrine insufficiency and its treatment with enteric coated pancreatin formulations.
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Dai, Dayou, and Hao Liu. "The Nervous System Contributes to the Tumorigenesis and Progression of Human Digestive Tract Cancer." Journal of Immunology Research 2022 (March 7, 2022): 1–11. http://dx.doi.org/10.1155/2022/9595704.
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Tumors of the gastrointestinal tract are one of the highest incidences of morbidity and mortality in humans. Recently, a growing number of researchers have indicated that nerve fibers and nerve signals participate in tumorigenesis. The current overarching view based on the responses to therapy revealed that tumors are partly promoted by the tumor microenvironment (TME), endogenous oncogenic factors, and complex systemic processes. Homeostasis of the neuroendocrine-immune axis (NEI axis) maintains a healthy in vivo environment in humans, and dysfunction of the axis contributes to various cancers, including the digestive tract. Interestingly, nerves might promote tumor development via multiple mechanisms, including perineural invasion (PNI), central level regulation, NEI axis effect, and neurotransmitter induction. This review focuses on the association between digestive tumors and nerve regulation, including PNI, the NEI axis, stress, and neurotransmitters, as well as on the potential clinical application of neurotherapy, aiming to provide a new perspective on the management of digestive cancers.
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Korochanskaya, N. V., V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, and K. I. Popandopulo. "Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients." Russian Journal of Gastroenterology, Hepatology, Coloproctology 29, no. 4 (September 23, 2019): 30–37. http://dx.doi.org/10.22416/1382-4376-2019-29-4-30-37.
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Aim. To analyse the dynamics of morbidity and mortality from diseases of the digestive system, as well as the quality of medical care for gastroenterological patients in the Krasnodar Krai.Materials and methods. The analysis was carried out according to C 51 “Distribution of deaths by gender, age groups and causes of death” form of the Territorial Authority of the Federal State Statistics Service for the Krasnodar Krai for the period from 2006 to 2018, as well as on the basis of the “Demography” block database of the Parus software of the healthcare management system of the Krasnodar Krai for 6 months of 2019. 1341 medical records of patients receiving outpatient medical care and the medical records of people who had died from digestive diseases in 2017-2019 were reviewed.Results. Digestive diseases (DD) occupy the fourth place (7.1 %) in the structure of the general morbidity of the population in the Krasnodar Krai. Over the study period (13 years), the structure of mortality from DD has not changed significantly among the region’s population. About 70% of the causes of death from DD among people of working age account for liver diseases. The pathology of the pancreas takes the second place (13.5 %). The peptic ulcer of the stomach, duodenum and “other diseases of the digestive system” (8.8 % and 7.7 %, respectively) are represented in almost equal shares. In the etiological structure of liver cirrhosis, viral (39 %) and alcoholic (36 %) liver diseases are leading. The frequency of viral liver lesions tends to decrease, while the proportion of liver cirrhosis in the outcome of non-alcoholic fatty liver disease (NAFLD) progressively increase, having reached 7 % in 2017–2018. In the group of patients with inflammatory diseases of the pancreas, men prevail (66.9 %), often those abusing alcohol. The third leading cause of mortality from DD in the Krasnodar Territory is pathological conditions that occurred in the upper gastrointestinal tract (acute stomach ulcer, duodenal ulcer with bleeding, perforation) in older age groups taking antiplatelet agents and non-steroidal anti-inflammatory drugs (71.8 %). Conclusions. The main causes of death among the population of the Krasnodar Krai from diseases of the digestive system at a young age are alcohol consumption with unhealthy consequences. At the same time, people of older age groups die from a lack of prevention of ulceration and inadequate eradication of Helicobacter pylori in patients taking non-steroidal anti-inflammatory drugs and antiplatelet agents.
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Sabău, David, and Grigore Friptuleac. "NUTRITIONAL AND BEHAVIOURAL PECULIARITIES OF THE POPULATION IN THE GENESIS OF DIGESTIVE DISEASES." Romanian Medical Journal 64, no. 2 (June 30, 2017): 121–32. http://dx.doi.org/10.37897/rmj.2017.2.5.
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Background. Digestive diseases, the third leading cause of death in Romania (4.9% of total deaths in 2010), are responsible for the annual loss of about 77 persons/100,000 population in 2009-2010, increasing compared to 2005. The large share these diseases have in pathology, high potential disabling of some of them, their interactions with environmental factors and food require their knowledge in early stages, treatment and prevention of complications. Aims. Aim of this study are to estimate the particularities of nutrition and the health of people with diseases of the digestive system, highlighting behavioral risk factors and preventive measures development in Cluj County. Methods. There were established two study groups, each made up of 255 people, including 1st lot that includes people taking one of the Cluj County digestive diseases known, and the 2nd lot that is being made of the population compared to the same county that have not been diagnosed diseases of the digestive tract. Results. In the study there were identified and prioritized key digestive disorders diagnosed in the group of subjects who are established in a particular period in Gastroenterology Clinic of Cluj Napoca. They determine relations between morbidity by diseases of the digestive and behavioral risk factors and they were developing preventive measures determining the impact of behavioral risk factors in the onset and development of diseases of the gastrointestinal tract. Conclusions. 1. In the conducted study found that digestive pathology had a wide representation among the investigated subjects, including all segments of the digestive tract. 2. At all digestive pathologies studied could not detect a single factor, each being able pathology could be assigned several factors (food, behavioral, environmental etc.). 3. Food factor can be considered as the predominant factor in the onset, maintenance or aggravation of digestive pathologies studied. 4. In the conducted study it was established as risk factors (along with the food) also smoking, alcohol consumption, a family history and even some vitamin deficiencies. 5. Extended studied digestive pathology is found distributed in proportions relative to the geographic areas studied area of Cluj County. On the regions, distribution percentages are so close that differences are considered unsignificant (North East – 22%, 23% – Northwest, Southwest - 29% and Southeast - 26%).
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Bakanova, E. O. "STRUCTURE OF THE BIRD MORBIDITY IN INDUSTRIAL GOOSE BREEDING." Scientific Notes Kazan Bauman State Academy of Veterinary Medicine 246, no. 2 (June 1, 2021): 14–18. http://dx.doi.org/10.31588/2413-4201-1883-246-2-14-18.
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The article presents the results of studying the structure of poultry morbidity in industrial goose-breeding enterprises: LLC "Poultry farm Kimovskaya" of the Republic of Mari El, LLC "Vurnarets" and OJSC "Brood poultry farm" Urmarskaya "of the Chuvash Republic. All three goose-breeding enterprises during the analyzed period of time were epizootologi-cally safe farms for infectious and invasive poultry diseases. It has been shown that the largest per-centage of diseases of non-infectious etiology in geese are metabolic diseases – up to 94.6 % and of the digestive system – up to 63.3 %, a high proportion of diseases of the egg production system – up to 40.2 %, which is due to the absence of veterinary treatment of poultry preventive measures against these diseases, and the low level of avitaminosis is explained by the active use of vitamin preparations in poultry farms. Most of the diseases occur in young animals: from 76.6 to 97.0 %, among broodstock the incidence in different years ranged from 3 to 23.4 %. Adjustment of thera-peutic and prophylactic treatment schemes for poultry, introduction of modern veterinary drugs can significantly reduce the incidence of non-communicable diseases in geese.
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Das, Anupam, MA Salam, Sultana Algin, MSI Mullick, Md Faruq Alam, ASMA Raihan, and Chanchal Kumar Ghosh. "Psychiatric morbidity among patients with irritable bowel syndrome." Bangladesh Journal of Psychiatry 32, no. 2 (December 31, 2020): 32–36. http://dx.doi.org/10.3329/bjpsy.v32i2.55127.
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Irritable Bowel Syndrome (IBS) is a functional disorder characterized by a set of gastrointestinal symptoms often associated with extra-digestive symptoms with unknown organic basis. It is a prototypic functional bowel disorder in terms of its heterogeneous nature with multifactor pathogenesis. Invariably it is co-morbid with psychiatric disorders. This study was done to determine the frequency and types of psychiatric disorders with irritable bowel syndrome and to find out association of socio-demographic and relevant variables. It was cross-sectional study carried out in the Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU) from January 2014 to December 2014. Total 250 sample were included by convenient sampling technique in this study diagnosed as IBS. Diagnosis was done according to Rome III criteria and SCID-CV was used for psychiatric assessment. Respondents were above 18 years of age of either sex. Data was analyzed using SPSS 20. Results showed 86.4% patients have psychiatric disorders. The most common disorder was generalized anxiety disorder (44.9%) followed by major depressive disorder (37.5%). Maximum (35.2%) were IBS-D type followed by 32.8% IBS-C type and 32% IBS-M type. So, it is seen that significant proportion of psychiatric disorders was found in patients with irritable bowel syndrome. Among them, generalized anxiety disorder was leading psychiatric disorder.
Bang J Psychiatry 2018;32(2): 32-36
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Wu, Chang, and Jun Wu. "Chimeric Antigen Receptor (CAR) T Cell Therapy for Digestive Tumor." E3S Web of Conferences 271 (2021): 03065. http://dx.doi.org/10.1051/e3sconf/202127103065.
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Digestive tumors commonly include esophageal cancer, gastric cancer, liver cancer, pancreatic cancer. Most of which are malignant tumors. All of the tumors do strong harm to human body and seriously affect the physical and mental health of patients. With the change of modern dietary habits, the morbidity of digestive tumors is increasing year by year, and the threat to the society is increasingly intensified. Traditional treatments for digestive tumors include surgical resection, chemotherapy and radiotherapy, all of which can alleviate the symptoms to some extent, but there are still many drawbacks. Compared with traditional therapy, immunotherapy has better therapeutic effect and fewer adverse reactions. Immunotherapy is to activate the human immune system and kill tumor cells by its own immune function. In immunotherapy, CAR-T cell therapy, a kind of personalized therapy that takes effect through gene modification to obtain T cells carrying tumor antigen-specific receptor, occupies a leading position. At present, CAR-T cells have shown excellent results in the treatment of lymphoid and hematopoietic tumors, on the contrast, there are few studies on the treatment of solid tumors. In this article, we summarized the application of some CAR-T cells in solid tumors of the digestive system.
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Polunin, Valеriy S., Abdul Majid Ali Al-Sabunchi, V. V. Korolik, and G. N. Buslayeva. "A STUDY OF THE MEDICO-SOCIAL ASPECTS OF MORBIDITY AMONG ADULTS AND CHILDREN IN THE ARAB COUNTRIES OF THE MIDDLE EAST." Medical Journal of the Russian Federation 24, no. 4 (August 15, 2018): 172–75. http://dx.doi.org/10.18821/0869-2106-2018-24-4-172-175.
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For morbidity is assessed the health of the population, which influence the socio-economic conditions and lifestyle factors, conditions and external factors Wednesday, biological conditions and factors, conditions and factors of the system and service health care. In Russia regularly examines the details of medico-demographic aspects of population health, but the necessary activities to enhance the health of the population of the countries of the Middle East hampered by various problems. Purpose - a study of the medico-social aspects of morbidity among adults and children in the Arab countries of the Middle East. Materials and methods. The research of health status of the population and the influence of socio-hygienic factors in Yemen, Iraq and Syria during the period of 2005-2010, studied modern informational materials on this issue. Results-the health status of the population of Yemen, Iraq and Syria is under the constant influence of the complex socio-hygienic factors mostly negative for the high morbidity of population, the low availability of medical assistance and health literacy, poor living conditions, material income. The first 5 places in the structure of morbidity of the population occupy: andnfekcionnye and parasitic diseases (28.3%), diseases of bodies of digestion (26.1%), respiratory (13.7%), circulatory (12.3%), injuries ( 3.6%), accounting for 83.5% of pathology. Total morbidity adult and children population of the countries surveyed the first three places are occupied by respiratory diseases, infectious diseases and diseases of the digestive system. Almost half of the urban population have daccess to primary health services in the countries studied, the inhabitants of the village-only every fourth. This process in the period from 2011 to 2017 years worsened in connection with military actions. Correction of the prevailing situation is possible only with the establishment of peace and the use of preventive recommendations.
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Sorokin, Gennadiy A. "The age and work experience dynamics of indices of health of employees as criteria for comparison of occupational and nonoccupational risks." Hygiene and sanitation 95, no. 4 (October 28, 2019): 355–60. http://dx.doi.org/10.18821/0016-9900-2016-95-4-355-360.
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There are reported data of the analysis ofparameters of the general morbidity (hypertension, chronic diseases, organs of respiratory and digestive system , adiposity, vertebral osteochondrosis) in dependence on age and work experience of dockers-mechanizators in seaport at various working conditions. Morbidity rate indices were calculated on results of the profound medical examination at annual periodic surveys of workers. There were analyzed ecological and ergonomic indices of working conditions, including an estimation of physiological intensity of the work. The general hygienic assessment of working conditions was executed on the basis of the measurement of rates of gains in the risk of diseases depending on age and the experience of work (an annual gain of risk). The divergence of these rates was used for the determination of occupational and nonoccupational fractions of the general morbidity in employees working in harmful conditions.
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Diaz, Ramon, Gerardo Davalos, and Alfredo Guerron. "Endoscopic Management of Gastrointestinal Bleeding." Digestive Disease Interventions 02, no. 04 (October 31, 2018): 314–20. http://dx.doi.org/10.1055/s-0038-1675414.
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Background Gastrointestinal bleeding (GIB) represents a significant cause of morbidity and mortality. The primary diagnostic and therapeutic tool is endoscopy. New devices are being developed and employed that facilitate the management of this pathology. In this review, we show the status of endoscopic management of digestive hemorrhage, current practices, and future directions. Methods We explore the management of patients with GIB (upper and lower). Besides, we analyzed the diagnostic methods in occult digestive hemorrhage. We show the evidence collected so far, and how each therapeutic method can be applied. Results GIB constitutes a challenge for the attending physician. Different therapeutic procedures are available. Less invasive devices have a role in the diagnosis but not therapy. The use of risk stratification is well established for upper bleeding, but for lower bleeding, there is still no evidence to support the use of these scores. Knowledge of altered anatomy is crucial in special populations. Conclusion A variety of procedures are available for the treatment of GIB. Emphasis should be placed on less invasive diagnostic techniques as well as on new and more efficient therapies. Attention should be given to the initial management, with timely diagnosis and effective resuscitation to decrease the morbidity and mortality.
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Gidenne, T., P. Arveux, and O. Madec. "The effect of the quality of dietary lignocellulose on digestion, zootechnical performance and health of the growing rabbit." Animal Science 73, no. 1 (April 2001): 97–104. http://dx.doi.org/10.1017/s1357729800058094.
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AbstractThe aim of this study was to evaluate the performance and digestive response of the growing rabbit according to a change in the nature of the lignocellulose (ADF), without a change in the ADF level. Three diets with a linearly decreasing lignin/cellulose ratio (ADL/cellulose = 0·8; 0·4; 0·2; respectively LC8, LC4, LC2) were given to a total of 162 rabbits per diet, from weaning till slaughter weight. A reduction of the ADL/cellulose ratio led to a lower food intake (LC8 v LC2: -11%), associated with a lower daily weight gain (-6% for LC2). Mortality and morbidity rate was significantly greater (+50%) for LC2 and LC4 diets compared with the LC8. Thus, the health risk index (morbidity + mortality) increased by 20 units for LC4 and LC2 compared with LC8 diet. In parallel, rate of passage was slower (mean retention time 4·5 h greater,P= 0045) with LC4 and LC2 diets. Dry-matter digestibility was slightly affected, whereas protein digestion was favoured with low ADL/cellulose ratio. It is recommended that a minimum lignin supply (about 6 g/day) is adopted as well as a minimum dietary lignocellulose to ensure growth performance and health of the growing rabbit.
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Najih, Mohammed, Mohamed Bouzroud, Aboulfeth El Mehdi, Bouchentouf Sidi Mohammed, El Kaoui Hakim, and Bounaim Ahmed. "THE SURGICAL BILIO-DIGESTIVE BYPASS BEFORE CEPHALIC PANCREATICODUODENECTOMY, REPORT OF EIGHT CASES." International Journal of Advanced Research 9, no. 09 (September 30, 2021): 840–43. http://dx.doi.org/10.21474/ijar01/13489.
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The cephalic pancreaticoduodenectomy (CPD) has a universally high morbidity and surgery in patients with obstructive jaundice is associated with a high risk of postoperative complications especially in patients with high bilirubin levels. For this reason, endoscopic preoperative biliary drainage (PBD) has been proposed to improve the postoperative courses.. Nevertheless, this solution is not always feasible and the use of a surgical bilio-digestive bypass may be necessary, which may complicate a later surgical procedure.In this work we report a case series of patients who underwent CPD preceded by a double surgical bypass and we analyze its impact on morbi-mortality.
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Hentati, Hassen, Chetana Lim, Chady Salloum, and Daniel Azoulay. "Authors’ Reply: Risk Factors for Mortality and Morbidity in Elderly Patients Presenting with Digestive Surgical Emergencies." World Journal of Surgery 42, no. 12 (June 8, 2018): 4129. http://dx.doi.org/10.1007/s00268-018-4701-z.
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Prykashchykova, K. Ye, Zh S. Yaroshenko, G. V. Kostiuk, V. I. Syrovenko, O. V. Olepir, V. O. Lukianiuk, I. V. Lytvyniuk, V. M. Polianska, and T. I. Movchun. "Non-neoplastic morbidity, disability, mortality in adult population at radioactively contaminated territories of Ukraine. Epidemiological research 1988-2016." Environment & Health 100 (3) (September 2021): 22–29. http://dx.doi.org/10.32402/dovkil2021.03.022.
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Objective: We presented a comprehensive description of the changes in the health status of the adult population of radioactively contaminated territories of Ukraine depending on gender and age at the date of the Chornobyl accident on the basis of cohort epidemiological studies after accident. Materials and methods: The epidemiological analysis of non-neoplastic morbidity, disability, mortality in the residents of radioactively contaminated territories (RCT) aged 18-60 years old at the date of the Chornobyl accident (65,189 people) was conducting during 1988-2016 for five-year observation periods and by eight classes of ICD-10. We applied the methods of mathematical and statistical analysis. Results: During 1988-2016, 90590 (100%) cases of non-neoplastic morbidity (34.94% in men and 65.06% in women), 11153 (100%) cases of disability (38.22% and61.78%, respectively), and 11586 (100%) cases of mortality(50,42% and 49,58%, respectively)were detected in the residents of the RCT for the first time as a result of epidemiological study. Most of the victims suffered from the nosological forms of the nosological forms of respiratory, circulatory and digestive systems, which made up 67.43% in the structure of non-neoplastic morbidity. Diseases of circulatory, endocrine and nervous systems (87.92%) were the main factors of disability and diseases of circulatory system (89.49%) - of mortality. The gender dependence of the development of the incidence of non-neoplastic diseases, disability and mortality due to them were established. The indices of mortality (116.08, ID/103 man-years of observation) and disability (13.57)in females significantly exceeded the males’ ones (86.57 and 11.65, respectively). But males had a higher mortality rate (16.01 vs. - 11.32). Changes in the incidence rates of non-neoplastic diseases, disability and mortality due to them throughout the observation period were characterized by a divergence of vectors: morbidity decreased, and disability and mortality increased simultaneously. The intersection of the dynamics of the mortality of non-neoplastic diseases with disability and mortality through those diseases was identified in 2008-2012. Conclusions 1. During epidemiological surveillance in 1988-2016, in the residents of RCT aged 18-60 years old on the date of the Chornobyl accident epidemiological surveillance, the non-neoplastic morbidity was formed mainly due to the significant development of diseases of the respiratory, circulatory and digestive systems, which together made up 67.43%. Non-neoplastic diseases of the circulatory, endocrine and nervous systems (87.92) were the main causes of disability, diseases of circulatory system (89.49%) - of mortality. 2. The gender dependence of the development of the morbidity of non-neoplastic diseases, disability and mortality in the residents of RCT over the thirty-year observation period was established. Diseases of the circulatory system were the main causes of disability and mortality. In males, disability and mortality were caused by the mental and behavioral disorders, diseases of respiratory and digestive systems, in females - by the diseases of nervous and urogenital systems. 3. In the residents of RCT, regardless of gender, over the years of observation, a feature of the development of morbidity, disability and mortality due to them was established, it was in the significant reduction of the incidence of diseases in 2008-2016, due to the increase of disability and mortality of the suffered, especially in 2008-2016, in comparison with the previous years, i.e. in 22-30 years after the Chornobyl accident. 4. Summarizing the obtained data, it is important to continue the epidemiological studies of the health status of the residents of RCT (non-neoplastic morbidity, disability, mortality) for the determination of the impact of radiation on the development of the main forms of non-neoplastic diseases.
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Rifatbegovic, Zijah, Zlatan Mehmedovic, Majda Mehmedovic, Jasmin Hasanovic, and Amra Mestric. "Multivisceral Resection with Performing a Double Roux-en-Y Reconstruction for Advanced Gastric Cancer." Case Reports in Surgery 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/649723.
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Background. The role of multivisceral resection, in the setting of locally advanced gastric cancer, is still debated. Previous studies have reported a higher risk for perioperative morbidity and mortality, with limited objective benefit in terms of survival.Patient.A male patient, 55 years old, was admitted to the clinic of surgery for surgical treatment of bleeding gastric ulceration. Preoperative diagnostic evaluation was performed, and patient had undergone a surgical treatment which revealed a large mass in head of the pancreas, infiltrating the hepatoduodenal ligament and transverse mesocolon. Total gastrectomy, duodenopancreatectomy, and right hemicolectomy were performed. The digestive tube continuity was reestablished by deriving the double Roux limbs.Conclusion. The aim of this case presentation is to demonstrate a method of digestive tube reconstruction by performing the double Roux-en-Y reconstruction in advanced gastric cancer when the multivisceral resection is performed.
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Islam, MS, MA Gafur, PK Deb, A. Bardhan, and L. Noor. "Study using endoscopic procedures for removal of foreign bodies from aero-digestive tract conducted in Jahurul Islam Medical College Hospital, Bangladesh." Mediscope 3, no. 1 (September 24, 2016): 22–27. http://dx.doi.org/10.3329/mediscope.v3i1.29732.
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Foreign bodies (FB) in the aero-digestive tract continue to be a common problem that contributes significantly to high morbidity and mortality worldwide. This study was conducted to describe our own experience with endoscopic procedures for removal of FB in the aero-digestive tract, in our local setting and compare with what is described in literature. This was a prospective descriptive study, which was conducted at Jahurul Islam Medical College Hospital between January, 2011 and January, 2014. Data were collected using a structured questionnaire and analyzed using SPSS computer software version 15. A total of 72 patients were studied. Males outnumbered females by a ratio of 1.4:1. Patients aged 2 years and below were the majority (75.9%). The commonest type of FB in airways was peanuts and coins. The trachea (52.2%) was the most common site of lodgment of FB in the airways, whereas cricopharyngeal sphincter (68.5%) was the commonest site in the esophagus. Rigid endoscopy with forceps removal under general anesthesia was the main treatment modality performed in 87.8% of patients. The FB were successfully removed without complications in 90.8% of cases. Complication rate was 7.1% and bronchopneumonia was the most common complication accounting for 42.8% of cases. The mean duration of hospital stay was 3 days and mortality rate was 4.1%. Aero-digestive tract FB continue to be a significant cause of childhood morbidity and mortality in our setting. Rigid endoscopic procedures under general anesthesia are the main treatment modalities performed. Prevention is highly recommended whereby parents should be educated to keep a close eye on their children and keep objects that can be FB away from childrens reach.Mediscope Vol. 3, No. 1: January 2016, Pages 22-27
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Rakhimov, B. B. "FEATURES OF THE MORBIDITY IN OBESE CHILDREN AND ADOLESCENTS OF THE REPUBLIC OF UZBEKISTAN." Hygiene and sanitation 96, no. 3 (March 27, 2019): 274–77. http://dx.doi.org/10.18821/0016-9900-2017-96-3-274-277.
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Aim of the study. To estimate the prevalence of the obesity in children and adult population of the Republic of Uzbekistan and the identification of the structure of the overall incidence of child and adolescent obesity. Methods. Clinical, analytical and statistical. The prevalence rate of obesity in the Republic of Uzbekistan in 2012-2014 among adults was founded to be of 31-34 ‰, in children - 50-66 ‰. Results. There was noted the gain in the rate obesity in children by 30% over 3 years. In contrast to children with normal weight, in the structure of diseases in obese children in order of significance there are dominated diseases of the endocrine system and nutrition disorders, respiratory diseases, diseases of the digestive system, diseases of the circulatory system and neuro - psychiatric disorders, amounting in total of 75% of all diseases.
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Patil, Rajashekhar T., and Advait Prakash. "Foreign bodies in aero-digestive tract in children: spectrum of presentation and management." International Surgery Journal 4, no. 6 (May 24, 2017): 1889. http://dx.doi.org/10.18203/2349-2902.isj20172128.
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Background: Foreign body (FB) ingestion and aspiration is quite common in children. It can be a life-threatening condition. Early diagnosis of foreign body aspiration is essential as delay in its recognition and treatment results in high morbidity and mortality. Symptoms seem to mostly depend on the anatomical location. The absence of specific symptoms indicating the occurrence of FB injury can lead to delay in diagnosis, thereby increasing the risk of complications.Methods: This is a prospective study which comprised of 50 patients with between 8 months and 4.5 years. FB involving different parts of the aero-digestive tract were included in the study. The site, side, symptoms and radiographic findings were recorded for each patient. Different procedures were used for retrieval of various FB at different locations. Majority of these procedures were performed under anaesthesia.Results: Most of the FB were organic in nature. Right side bronchus was more commonly involved. A combination of different procedures was used according to the site involved. All the FB were removed successfully and smoothly. There was minimum morbidity with no mortality and the overall outcome was excellent. Hospital stay varied according to the site of involvement.Conclusions: The symptoms of FB change with the site involved and many patients are even asymptomatic. A differential diagnosis of foreign body should always be made in an acute or chronic presentation of respiratory cases. Aspiration of foreign body should be suspected in all cases of broncho-pulmonary infection with atypical course. High index of suspicion is the cornerstone of diagnosis. Bronchoscopy is the best diagnostic and therapeutic method in all suspicions of foreign body of tracheo-bronchial tree. Proper and timely intervention optimizes the outcome.
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Aleshina, Natalya Yu. "Content of radionuclides and public health of environmentally disadvantaged region." Russian Journal of Occupational Health and Industrial Ecology 60, no. 11 (December 3, 2020): 713–16. http://dx.doi.org/10.31089/1026-9428-2020-60-11-713-716.
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Relevance. The main source of radionuclide contamination in Kazakhstan is the Semipalatinsk nuclear test site (SNTS), where more than 460 nuclear explosions were made. There are still people living in some areas of the SNTS. The source of radionuclides entering the human body is animal food. The aim of the study was to study the content of 137Cs and 90Sr radionuclides in cattle meat and their impact on public health in areas close to the SNTS. Materials and methods. The data on the content of radionuclides were obtained at the Semipalatinsk Regional Veterinary Laboratory of the East Kazakhstan Region. The object of the study was meat of cattle (cattle) (67 samples) obtained in Abai, Borodulikhinsky, Zharminsky, Beskaragaysky districts and the city of Semipalatinsk, East Kazakhstan region, adjacent to the SNTS. The retrospective of the analyzed indicators was 10 years (1991-2000). The sources of information on the incidence of the entire population in the regions of East Kazakhstan region were data obtained from the Republican Center for Electronic Health for the period 2000-2015. Mathematical and statistical processing of the results was carried out using the applied statistical program Statistica-10. Results. The average content of 137Cs in cattle meat was 0.15 Bq/kg, and 90Sr - 0.11 Bq/kg. The dynamics revealed a 1.9-fold decrease in the level of 137Cs and a 2-fold decrease in the level of 90Sr. The consumption of cattle meat by residents was 14.7%. The average morbidity level of diseases of the musculoskeletal system was 3305 ppm. The morbidity of endocrine system diseases increased 1.4 times in dynamics. The morbidity level of diseases of the digestive system was 3358.9 ppm and decreased by 24.6% in dynamics. A correlation was found between the consumption of cattle meat and the morbidity level of diseases of the musculoskeletal system r=0.78. Conclusions. The study showed a positive trend of reducing the level of radionuclides in cattle meat among the studied regions. There was an increase in the average morbidity level of diseases of the musculoskeletal system by 1.2 times, and the endocrine system by 1.4 times. There is a trend to reduce the morbidity of diseases of the digestive system in the population of the studied regions. The revealed relationship between the consumption of cattle meat and the incidence of the musculoskeletal system diseases requires further study and monitoring.
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Roncevic, Nevenka, Jelena Popadic-Gacesa, Vera Grujic, Miodrag Arsic, and Ivana Pericin. "Hospital morbidity and mortality of adolescents in Vojvodina." Medical review 62, no. 3-4 (2009): 137–41. http://dx.doi.org/10.2298/mpns0904137r.
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Introduction. The aim of this study was to analyze hospital morbidity and mortality of adolescents in Vojvodina in 2004. Material and methods. The analyzed data for hospital morbidity were obtained from the Reports on diseases and conditions of hospitalized patients in the Service for stationary-hospital treatment. Hospital mortality was analyzed on the basis of Documentation tables of vital statistics of Republic of Serbia. In order to have better insight into the pathology, the adolescents were divided by sex and age (the younger ones from 10-14 years, and the older ones, from 15-19 years). Results . The hospital morbidity of adolescents in Vojvodina in 2004 was 47/1.000 adolescents, while in 1983 it was 53/1.000 adolescents. The most frequent indications for hospitalization of the adolescents were respiratory, digestive diseases, and injuries, poisoning and consequences of an external factor influences. The overall mortality rate was 39.68/100.000 adolescents and in 1988 44.74/100.000 adolescents. Hospital mortality rate in Vojvodina in 2004 was 16.18/100.000 adolescents and in 1986 11.65/100.000 adolescents. The male adolescents most frequently died in hospitals because of tumors, and female ones because of injuries, poisoning and consequences of external factor influences. Discussion and conclusion. Morbidity structure was not changed compared to the previous period. Older and female adolescents were more frequently hospitalized. There was a decrease in adolescent mortality for 15.5% compared to the previous 15 years. Hospital mortality rate was higher than before. Older adolescents had three times the death rate of younger. Mortality rates for male adolescents were three times rates for females. Programs for adolescents' health care must be implemented fully, with engagement of whole community services, in order to prevent and cure diseases adequately and to enhance quality of life.
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Yaseneva, Irina, and Elena Yaseneva. "Children morbidity as indicator of ecological situation in Sevastopol." InterCarto. InterGIS 26, no. 3 (2020): 62–77. http://dx.doi.org/10.35595/2414-9179-2020-3-26-62-77.
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The aim of this study was to define the factors that have a negative impact on public health. Knowledge in this field is an additional tool for the environmental quality management in the context of preserving and strengthening of the child population health. The geoformation material of the children’s morbidity has an important information about the health of the population and the environmental impact on it. Industrial enterprises influence air pollution: Sevgorvodokanal DKP Balaklava State Mining Administration, Sevtets DP, Sevteploenergo KP, Yugtorsan LLC. Pollutants such as inorganic dust, carbon monoxide, sulfur dioxide, nitric oxide, which increase the incidence of respiratory diseases, increase mortality from diseases of the respiratory system and the cardiovascular system, are present in the air basin. The results of the study are based on statistical data collected by the author in the Territorial Bodies of the Federal State Statistics Service for cities and districts, regional health organizations (Sevastopol Health Department), and city polyclinics in the study area. The dataset included information on the demographic situation, as well as medical statistics (morbidity and mortality according to the international classification of diseases). Analysis of the medical and environmental status of the city of Sevastopol was carried out taking into account the criteria of the environmentally dependent diseases of the child population (age group from 0 to 17 years). Assessment of the incidence of children in the city of Sevastopol, showed that respiratory diseases occupy a leading place in the structure of the general incidence rate, digestive apparatus diseases take the 2nd place and the nervous system disease takes the third one.
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Aurélia, Rakotondrainibe. "DOES TIMING OF DIGESTIVE ENDOSCOPY AFFECT MORBIDITY AND MORTALITY OF UPPER GASTROINTESTINAL BLEEDING IN A MALAGASY POPULATION?" International Journal of Advanced Research 6, no. 1 (January 31, 2018): 589–95. http://dx.doi.org/10.21474/ijar01/6260.
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Almuslim, Osama, and Ron Butler. "Best evidence in critical care medicine Selective digestive decontamination decreases mortality and morbidity in the intensive care." Canadian Journal of Anesthesia/Journal canadien d'anesthésie 51, no. 7 (August 2004): 737–39. http://dx.doi.org/10.1007/bf03018436.
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Y, Dicko M., Katile D, Tounkara M. S, Soumare G, Doumbia N, Doumbia K. Épouse Samake, Sow H. Épouse Coulibaly, et al. "Gastrointestinal Bleeding and Non-Steroidal Anti-Inflammatory Drugs in Hospitals in Bamako, Mali." SAS Journal of Medicine 8, no. 4 (April 26, 2022): 340–44. http://dx.doi.org/10.36347/sasjm.2022.v08i04.024.
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The main aim of this study was to investigate the role of non-steroidal anti-inflammatory drugs in digestive bleeding in a hospital setting and in a context of social and security instability. Patients and methods: This was a prospective and analytical study that took place in the Hepato-Gastroenterology Department of the Gabriel TOURE University Hospital over a period of two years and included all patients hospitalized for digestive hemorrhage. These patients had benefited from the research of sociodemographic characteristics, the notion of taking non-steroidal anti-inflammatory drugs (dose and duration), a physical examination and a digestive endoscopy. Results: At the end of this study, 78 cases of non-steroidal anti-inflammatory drug use out of 210 patients hospitalized for digestive hemorrhage were recorded, i.e. a frequency of 37.1%. The mean age of our patients was 47.01±19.3 years with a sex ratio of 2.9. Housewives and farmers represented 28.2% and 20.5% respectively. Hematemesis was the reason for consultation in 71.8%. Digestive hemorrhage and smoking were the most common antecedents. Diclofenac was the most commonly used drug in 53.9% of cases, with bleeding occurring in the first week after taking the non-steroidal anti-inflammatory drug in 53.9% of cases. Signs of hypovolemic shock were frequently found. The GD ulcer was the cause found in 66.2% of cases. Hemorrhage occurred significantly (p=10-8) in the first week of taking non-steroidal anti-inflammatory drugs and was significantly associated with NSAID use. There was no statistically significant difference in the occurrence of death between the molecules. Conclusion: NSAID-induced GI bleeding in adults is one of the major GI emergencies and remains an important cause of morbidity and mortality.
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GARANINA, Lilia Andreevna, and Artem Aleksandrovich NAZAROV. "The role of a nurse in providing medical care for acute cholecystitis." Vrač skoroj pomoŝi (Emergency Doctor), no. 1 (January 1, 2021): 19–27. http://dx.doi.org/10.33920/med-02-2101-02.
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There is no doubt that the correct functioning of the gastrointestinal tract is the key to good health of the whole organism. In the current living conditions, where stress, fatigue, inappropriate nutrition, and unfavorable environmental conditions have become an integral part of a modern person’s life, the disorders associated with the work of the gastrointestinal tract are quite common and strongly affect the quality of a person’s life. Therefore, an appointment with a gastroenterologist should not be postponed. This article presents the data confirming that the pathology of the digestive system stably ranks second in the structure of morbidity and causes of death, giving way to diseases of the respiratory and cardiovascular systems. Modern diagnostic methods in gastroenterology (ultrasound diagnostics, esophagoscopy, gastroscopy, laparoscopy, rectoscopy, radiological studies, a large number of laboratory techniques) make it possible to identify diseases of the digestive system in the early stages and to carry out effective prevention and treatment.
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Bjelovic, Milos, Tamara Babic, Dragan Gunjic, Milan Veselinovic, and Bratislav Spica. "Minimally invasive esophagectomy for cancer: Single center experience after 44 consecutive cases." Srpski arhiv za celokupno lekarstvo 143, no. 7-8 (2015): 410–15. http://dx.doi.org/10.2298/sarh1508410b.
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Introduction. At the Department of Minimally Invasive Upper Digestive Surgery of the Hospital for Digestive Surgery in Belgrade, hybrid minimally invasive esophagectomy (hMIE) has been a standard of care for patients with resectable esophageal cancer since 2009. As a next and final step in the change management, from January 2015 we utilized total minimally invasive esophagectomy (tMIE) as a standard of care. Objective. The aim of the study was to report initial experiences in hMIE (laparoscopic approach) for cancer and analyze surgical technique, major morbidity and 30-day mortality. Methods. A retrospective cohort study included 44 patients who underwent elective hMIE for esophageal cancer at the Department for Minimally Invasive Upper Digestive Surgery, Hospital for Digestive Surgery, Clinical Center of Serbia in Belgrade from April 2009 to December 2014. Results. There were 16 (36%) middle thoracic esophagus tumors and 28 (64%) tumors of distal thoracic esophagus. Mean duration of the operation was 319 minutes (approximately five hours and 20 minutes). The average blood loss was 173.6 ml. A total of 12 (27%) of patients had postoperative complications and mean intensive care unit stay was 2.8 days. Mean hospital stay after surgery was 16 days. The average number of harvested lymph nodes during surgery was 31.9. The overall 30-day mortality rate within 30 days after surgery was 2%. Conclusion. As long as MIE is an oncological equivalent to open esophagectomy (OE), better relation between cost savings and potentially increased effectiveness will make MIE the preferred approach in high-volume esophageal centers that are experienced in minimally invasive procedures.
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Zelenina, N. V., I. V. Fedotkina, and V. V. Yusupov. "Personality traits as predictors of stress-induced somatic diseases in military academy cadets." Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations, no. 2 (June 17, 2020): 93–99. http://dx.doi.org/10.25016/2541-7487-2020-0-2-93-99.
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Relevance. The need to improve medical and psychological support for cadets of higher military educational institutions in order to reduce disease incidence and subsequent dismissal of military professionals for health reasons. Intention. To identify personality-associated predictors of stress-induced somatic diseases in cadets.Methodology. 433 male cadets aged 21-24 years in their 5-6th year of training were examined. We used the D. Keirsey personality questionnaire and the Giessen personality inventory. Somatic morbidity was analyzed based on the results of annual medical examinations and correlated with the International classification of diseases, injuries and behavioral disorders, 10th revision (ICD-10).Results and Discussion. The growth of somatic morbidity of cadets in the course of training was established. Diseases of the digestive system (K00–K93 according to ICD-10) were most common, their percentage increased from 0 % in the first year to 7.3 % in the 5-6th years of training. Diseases of the circulatory system (I00–I99) and diseases of the skin and subcutaneous tissue (L00–L99) increased up to 2.7 %. Personality characteristics of cadets have been studied. Typological and psychosocial personality characteristics associated with the risk of health disorders in the learning process were identified.Conclusion. Typological and psychosocial personality traits can be predictors of stress-induced somatic diseases in cadets in the course of training. Vulnerability to cardiovascular diseases is closer associated with typological personality traits, to skin diseases – with psychosocial traits, and diseases of the digestive system correlated with both typological and psychosocial personality traits.