Journal articles on the topic 'Differentiation checkpoint'
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Polesskaya, Anna, and Michael A. Rudnicki. "A MyoD-Dependent Differentiation Checkpoint." Developmental Cell 3, no. 6 (December 2002): 757–58. http://dx.doi.org/10.1016/s1534-5807(02)00372-6.
Full textMunz, Barbara, Eberhard Hildt, Matthew L. Springer, and Helen M. Blau. "RIP2, a Checkpoint in Myogenic Differentiation." Molecular and Cellular Biology 22, no. 16 (August 15, 2002): 5879–86. http://dx.doi.org/10.1128/mcb.22.16.5879-5886.2002.
Full textSell, Stewart, and Zoran Ilic. "Comparison of survivor scores for differentiation therapy of cancer to those for checkpoint inhibition: Half full or half empty." Tumor Biology 41, no. 9 (September 2019): 101042831987374. http://dx.doi.org/10.1177/1010428319873749.
Full textVining, Kyle H., Anna E. Marneth, Kwasi Adu-Berchie, Christina M. Tringides, Joshua M. Grolman, Yutong Liu, Waihay J. Wong, et al. "Mechanical Checkpoint Regulates Monocyte Differentiation in Fibrotic Matrix." Blood 138, Supplement 1 (November 5, 2021): 2539. http://dx.doi.org/10.1182/blood-2021-147297.
Full textPuri, Pier Lorenzo, Kunjan Bhakta, Lauren D. Wood, Antonio Costanzo, Jiangyu Zhu, and Jean Y. J. Wang. "A myogenic differentiation checkpoint activated by genotoxic stress." Nature Genetics 32, no. 4 (November 4, 2002): 585–93. http://dx.doi.org/10.1038/ng1023.
Full textKrauss, Jennifer L., Rong Zeng, Cynthia L. Hickman-Brecks, Justin E. Wilson, Jenny P. Y. Ting, and Deborah V. Novack. "NLRP12 provides a critical checkpoint for osteoclast differentiation." Proceedings of the National Academy of Sciences 112, no. 33 (August 3, 2015): 10455–60. http://dx.doi.org/10.1073/pnas.1500196112.
Full textRoth, Therese M., C. Y. Ason Chiang, Mayu Inaba, Hebao Yuan, Viktoria Salzmann, Caitlin E. Roth, and Yukiko M. Yamashita. "Centrosome misorientation mediates slowing of the cell cycle under limited nutrient conditions in Drosophila male germline stem cells." Molecular Biology of the Cell 23, no. 8 (April 15, 2012): 1524–32. http://dx.doi.org/10.1091/mbc.e11-12-0999.
Full textRabadi, Dina, Alia A. Sajani, Randolph J. Noelle, and J. Louise Lines. "The role of VISTA in the tumor microenvironment." Journal of Cancer Metastasis and Treatment 8, no. 5 (2022): 24. http://dx.doi.org/10.20517/2394-4722.2022.06.
Full textAbbadi, Dounia, Ming Yang, Devon M. Chenette, John J. Andrews, and Robert J. Schneider. "Muscle development and regeneration controlled by AUF1-mediated stage-specific degradation of fate-determining checkpoint mRNAs." Proceedings of the National Academy of Sciences 116, no. 23 (May 21, 2019): 11285–90. http://dx.doi.org/10.1073/pnas.1901165116.
Full textDirlam, Alexandra, Benjamin T. Spike, and Kay F. Macleod. "E2f-2 Regulates Caspase-3 Expression and Mitotic Checkpoint Control during End-Stage Erythroid Maturation." Blood 106, no. 11 (November 16, 2005): 307. http://dx.doi.org/10.1182/blood.v106.11.307.307.
Full textAndrews, Lauren B., Alec A. K. Nielsen, and Christopher A. Voigt. "Cellular checkpoint control using programmable sequential logic." Science 361, no. 6408 (September 20, 2018): eaap8987. http://dx.doi.org/10.1126/science.aap8987.
Full textMaeda, Yasuo. "Cell-cycle checkpoint for transition from cell division to differentiation." Development, Growth & Differentiation 53, no. 4 (May 2011): 463–81. http://dx.doi.org/10.1111/j.1440-169x.2011.01264.x.
Full textGandarillas, Alberto, Rut Molinuevo, Ana Freije, and Pilar Alonso-Lecue. "The mitosis-differentiation checkpoint, another guardian of the epidermal genome." Molecular & Cellular Oncology 2, no. 3 (January 21, 2015): e997127. http://dx.doi.org/10.1080/23723556.2014.997127.
Full textMartinikova, Andra S., Monika Burocziova, Miroslav Stoyanov, and Libor Macurek. "Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma." Cells 9, no. 9 (September 10, 2020): 2068. http://dx.doi.org/10.3390/cells9092068.
Full textKondratova, Maria, Emmanuel Barillot, Andrei Zinovyev, and Laurence Calzone. "Modelling of Immune Checkpoint Network Explains Synergistic Effects of Combined Immune Checkpoint Inhibitor Therapy and the Impact of Cytokines in Patient Response." Cancers 12, no. 12 (December 2, 2020): 3600. http://dx.doi.org/10.3390/cancers12123600.
Full textJiang, Yi Wei, and Christopher Minkyu Kang. "Induction of S. cerevisiae Filamentous Differentiation by Slowed DNA Synthesis Involves Mec1, Rad53 and Swe1 Checkpoint Proteins." Molecular Biology of the Cell 14, no. 12 (December 2003): 5116–24. http://dx.doi.org/10.1091/mbc.e03-06-0375.
Full textXiao, Qingyang, André Nobre, Pilar Piñeiro, Miguel-Ángel Berciano-Guerrero, Emilio Alba, Manuel Cobo, Volker Lauschke, and Isabel Barragán. "Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response." Journal of Clinical Medicine 9, no. 1 (January 20, 2020): 286. http://dx.doi.org/10.3390/jcm9010286.
Full textZha, Zhao, Felicitas Bucher, Anahita Nejatfard, Tianqing Zheng, Hongkai Zhang, Kyungmoo Yea, and Richard A. Lerner. "Interferon-γ is a master checkpoint regulator of cytokine-induced differentiation." Proceedings of the National Academy of Sciences 114, no. 33 (July 31, 2017): E6867—E6874. http://dx.doi.org/10.1073/pnas.1706915114.
Full textChann, Anchi S., and Sarah M. Russell. "An integrated transcriptional switch at the β-selection checkpoint determines T cell survival, development and leukaemogenesis." Biochemical Society Transactions 47, no. 4 (June 27, 2019): 1077–89. http://dx.doi.org/10.1042/bst20180414.
Full textDerakhshani, Afshin, Zeinab Rostami, Hossein Safarpour, Mahdi Abdoli Shadbad, Niloufar Sadat Nourbakhsh, Antonella Argentiero, Sina Taefehshokr, et al. "From Oncogenic Signaling Pathways to Single-Cell Sequencing of Immune Cells: Changing the Landscape of Cancer Immunotherapy." Molecules 26, no. 8 (April 14, 2021): 2278. http://dx.doi.org/10.3390/molecules26082278.
Full textWong, Gladys, Juan Carlos Zuniga-Pflucker, Gisele Knowles, Tak Mak, and Adolfo Ferrando. "Molecular targets of Notch signaling, HES1 and c-Myc, oppose a PTEN-dependent check on survival, differentiation and proliferation of TCR-beta-selected thymocytes (111.21)." Journal of Immunology 188, no. 1_Supplement (May 1, 2012): 111.21. http://dx.doi.org/10.4049/jimmunol.188.supp.111.21.
Full textSrour, Nivine, Guillaume Chemin, Aurélien Tinguely, Mohamad Omar Ashi, Zéliha Oruc, Sophie Péron, Christophe Sirac, Michel Cogné, and Laurent Delpy. "A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production." Journal of Experimental Medicine 213, no. 1 (December 14, 2015): 109–22. http://dx.doi.org/10.1084/jem.20131511.
Full textQin, Yuling, Meiqin Li, Qiumei Lin, Xiaolan Pan, Yihua Liang, Zhaodong Huang, Zhimin Liu, Lingsha Huang, and Min Fang. "Colorectal Cancer Cell Differentiation Trajectory Predicts Patient Immunotherapy Response and Prognosis." Cancer Control 29 (January 2022): 107327482211213. http://dx.doi.org/10.1177/10732748221121382.
Full textWong, Gladys W., Gisele C. Knowles, Tak W. Mak, Adolfo A. Ferrando, and Juan Carlos Zúñiga-Pflücker. "HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes." Blood 120, no. 7 (August 16, 2012): 1439–48. http://dx.doi.org/10.1182/blood-2011-12-395319.
Full textUllah, Z., C. de Renty, and M. L. DePamphilis. "Checkpoint Kinase 1 Prevents Cell Cycle Exit Linked to Terminal Cell Differentiation." Molecular and Cellular Biology 31, no. 19 (July 26, 2011): 4129–43. http://dx.doi.org/10.1128/mcb.05723-11.
Full textGandarillas, Alberto. "The mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint." Cell Cycle 11, no. 24 (December 15, 2012): 4507–16. http://dx.doi.org/10.4161/cc.22529.
Full textYang, Fan, Yan Zhao, Xiaohan Huang, Jin Zhang, and Ting Zhang. "A Cell Differentiation Trajectory-Related Signature for Predicting the Prognosis of Lung Adenocarcinoma." Genetics Research 2022 (August 16, 2022): 1–11. http://dx.doi.org/10.1155/2022/3483498.
Full textHirose, S., Y. Inazu, S. Chae, and Y. Maeda. "Suppression of the growth/differentiation transition in Dictyostelium development by transient expression of a novel gene, dia1." Development 127, no. 15 (August 1, 2000): 3263–70. http://dx.doi.org/10.1242/dev.127.15.3263.
Full textSarkar, Sukumar, Bijan K. Dey, and Anindya Dutta. "MiR-322/424 and -503 Are Induced during Muscle Differentiation and Promote Cell Cycle Quiescence and Differentiation by Down-Regulation of Cdc25A." Molecular Biology of the Cell 21, no. 13 (July 2010): 2138–49. http://dx.doi.org/10.1091/mbc.e10-01-0062.
Full textIsoda, Takeshi, Masatoshi Takagi, Jinhua Piao, Shun Nakagama, Masaki Sato, Kyoko Masuda, Tomokatsu Ikawa, et al. "T-Cell Development Failure At β-Selection Checkpoint and TCRα/δ Locus Break Formation Associated with Chromosome 14 Translocation in Ataxia-Telangiectagia Mutated Deficient Mice." Blood 118, no. 21 (November 18, 2011): 184. http://dx.doi.org/10.1182/blood.v118.21.184.184.
Full textYu, Jin. "Efficient fidelity control by stepwise nucleotide selection in polymerase elongation Abstract: Polymerases select nucleotides." Computational and Mathematical Biophysics 2, no. 1 (January 1, 2014): 141–60. http://dx.doi.org/10.2478/mlbmb-2014-0010.
Full textAnsa-Addo, Ephraim A., Huai-Cheng Huang, Brian Riesenberg, Supinya Iamsawat, Davis Borucki, Michelle H. Nelson, Jin Hyun Nam, et al. "RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity." Science Advances 6, no. 22 (May 2020): eaaz3865. http://dx.doi.org/10.1126/sciadv.aaz3865.
Full textShinnick, Kathryn M., Kelly A. Barry, Elizabeth A. Eklund, and Thomas J. McGarry. "Geminin Regulates Hematopoietic Stem Cell Proliferation and Differentiation." Blood 114, no. 22 (November 20, 2009): 1478. http://dx.doi.org/10.1182/blood.v114.22.1478.1478.
Full textOConnor, Roddy, Lili Guo, Saba Ghassemi, Nathaniel Snyder, Andrew Worth, Liwei Weng, Shaun OBrien, et al. "Hypoxia-induced reactive oxygen species contribute to immune checkpoint molecule expression in T cells undergoing rapid clonal proliferation." Journal of Immunology 200, no. 1_Supplement (May 1, 2018): 108.18. http://dx.doi.org/10.4049/jimmunol.200.supp.108.18.
Full textXu, Jin, Xi Chen, Yinyu Chen, Qiushuang Wang, Yingliang Jin, and Huashuo Zhao. "Cell Differentiation Trajectory Predicts Prognosis and Immunotherapeutic Response in Clear Cell Renal Cell Carcinoma." Genetics Research 2022 (November 29, 2022): 1–19. http://dx.doi.org/10.1155/2022/8422339.
Full textDevarajan, Priyadharshini, Allen M. Vong, Bianca Bautista, Catherine H. Castonguay, and Susan L. Swain. "Antigen Presenting Cells as Drivers of Specialized Immune Responses." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 133.14. http://dx.doi.org/10.4049/jimmunol.196.supp.133.14.
Full textDong, Juan, Cassandra Gilmore, Hieu Ta, Keman Zhang, Sarah Stone, and Li Wang. "501 VISTA regulates the differentiation and suppressive function of myeloid-derived suppressor cells." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (November 2020): A536. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0501.
Full textSchetters, Sjoerd T. T., Ernesto Rodriguez, Laura J. W. Kruijssen, Matheus H. W. Crommentuijn, Louis Boon, Jan Van den Bossche, Joke M. M. Den Haan, and Yvette Van Kooyk. "Monocyte-derived APCs are central to the response of PD1 checkpoint blockade and provide a therapeutic target for combination therapy." Journal for ImmunoTherapy of Cancer 8, no. 2 (July 2020): e000588. http://dx.doi.org/10.1136/jitc-2020-000588.
Full textRenga, Giorgia, Marina M. Bellet, Marilena Pariano, Marco Gargaro, Claudia Stincardini, Fiorella D’Onofrio, Paolo Mosci, et al. "Thymosin α1 protects from CTLA-4 intestinal immunopathology." Life Science Alliance 3, no. 10 (August 14, 2020): e202000662. http://dx.doi.org/10.26508/lsa.202000662.
Full textZhou, Liye, Zexian Zeng, Ann Marie Egloff, Fan Zhang, Fei Guo, Katie M. Campbell, Peter Du, et al. "Checkpoint blockade-induced CD8+ T cell differentiation in head and neck cancer responders." Journal for ImmunoTherapy of Cancer 10, no. 1 (January 2022): e004034. http://dx.doi.org/10.1136/jitc-2021-004034.
Full textTaghon, Tom, Inge Van de Walle, Greet De Smet, Magda De Smedt, Georges Leclercq, Bart Vandekerckhove, and Jean Plum. "Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development." Blood 113, no. 14 (April 2, 2009): 3254–63. http://dx.doi.org/10.1182/blood-2008-07-168906.
Full textde Joode, Karlijn, Sharon Veenbergen, Claudia Kransse, Dian Kortleve, Reno Debets, Ron H. J. Mathijssen, Arjen Joosse, Marco W. J. Schreurs, and Astrid A. M. Van der Veldt. "Suitability of tumor-associated antibodies as predictive biomarker for response to immune checkpoint inhibitors in patients with melanoma: a short report." Journal for ImmunoTherapy of Cancer 11, no. 2 (February 2023): e006467. http://dx.doi.org/10.1136/jitc-2022-006467.
Full textAzouz, Nurit P., Mario A. Ynga-Durand, Julie M. Caldwell, Ayushi Jain, Mark Rochman, Demetria M. Fischesser, Leanne M. Ray, et al. "The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses." Science Translational Medicine 10, no. 444 (June 6, 2018): eaap9736. http://dx.doi.org/10.1126/scitranslmed.aap9736.
Full textSmith, Lucas R., Jerome Irianto, Yuntao Xia, Charlotte R. Pfeifer, and Dennis E. Discher. "Constricted migration modulates stem cell differentiation." Molecular Biology of the Cell 30, no. 16 (July 22, 2019): 1985–99. http://dx.doi.org/10.1091/mbc.e19-02-0090.
Full textMiao, Tizong, Alistair L. J. Symonds, Randeep Singh, Janine D. Symonds, Ane Ogbe, Becky Omodho, Bo Zhu, Suling Li, and Ping Wang. "Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation." Journal of Experimental Medicine 214, no. 6 (May 9, 2017): 1787–808. http://dx.doi.org/10.1084/jem.20160553.
Full textLapenta, Caterina, Lucia Gabriele, and Stefano Maria Santini. "IFN-Alpha-Mediated Differentiation of Dendritic Cells for Cancer Immunotherapy: Advances and Perspectives." Vaccines 8, no. 4 (October 19, 2020): 617. http://dx.doi.org/10.3390/vaccines8040617.
Full textKim, Young Jae, Chong Hyun Won, Mi Woo Lee, Jee Ho Choi, Sung Eun Chang, and Woo Jin Lee. "Correlation Between Tumor-Associated Macrophage and Immune Checkpoint Molecule Expression and Its Prognostic Significance in Cutaneous Melanoma." Journal of Clinical Medicine 9, no. 8 (August 3, 2020): 2500. http://dx.doi.org/10.3390/jcm9082500.
Full textLi, Jia, and Yuan Zhuang. "Double knockout of Id2 & Id3 in developing T cells promotes the development of CD4-CD8- αβ T cell (63.3)." Journal of Immunology 188, no. 1_Supplement (May 1, 2012): 63.3. http://dx.doi.org/10.4049/jimmunol.188.supp.63.3.
Full textShi, Lewis Z., Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R. Green, and Hongbo Chi. "HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells." Journal of Experimental Medicine 208, no. 7 (June 27, 2011): 1367–76. http://dx.doi.org/10.1084/jem.20110278.
Full textRoy, Lydia, Philippe Coullin, Natacha Vitrat, Raymond Hellio, Najet Debili, Jasminder Weinstein, Alain Bernheim, and William Vainchenker. "Asymmetrical segregation of chromosomes with a normal metaphase/anaphase checkpoint in polyploid megakaryocytes." Blood 97, no. 8 (April 15, 2001): 2238–47. http://dx.doi.org/10.1182/blood.v97.8.2238.
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