Dissertations / Theses on the topic 'Dibb'
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Lee, Jean-Philip, and Johan Andersson. "Diab Control System." Thesis, Högskolan i Halmstad, Akademin för informationsteknologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-37011.
Full textMehmedovic, Edin. "Värdeflödesanalys på DIAB AB Laholm." Thesis, Jönköping University, JTH, Industrial Engineering and Management, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-370.
Full textThis report is the result of a 20-points project at the University of Jönköping. The project was carried out in form of a case study with the object of analysing the value flow at DIAB AB’s confection department in Laholm. The aim of this project is to submit proposals to the production management on how to increase the efficiency of the production flow at the confection department and reduce the capital accumulation in form of products in work.
The information in this report is gathered from interviews, observations and measurements. Furthermore, a literature study was carried out in view to find suitable theories when analysing present as well as future suggested production conditions.
This report is based on four main questions:
• What does the existing process of the value flow for the most produced product family look like?
• How does the process of the value flow for GS perform considering the through-put-time?
o How long through-put-time does a representative product of the GS-family have?
o How long is the value- and no value adding time for that product along its production flow?
• Which production related disturbances and cost prompters exist in the present value flow process?
• How could the process of the value flow for GS be made more efficient, less persistent to disturbances and more competitive?
The existing process of the value flow for the most producing product family has been mapped and is illustrated in appendix 3. For now, the process includes nine working stations along the production chain.
The through-put-time of a representative GS-product is according to my survey 18,5 days. The value adding time is only 16,1 minutes, that is 0,061 % of the entire through-put-time. The remaining time, in other words the no value adding time, is 440 hours and it represents mainly storage and transport of products.
The representative production disturbances and cost prompters that characterise the process of the value flow contain material related disturbances, a high number of long shifts, long storage time prior to the customer order point and with that, high capital accumulation and finally unnecessary transports.
Improvement proposals aim to increase the efficacy of the process of the value flow and reduce the capital amounts by shifting from the present production strategy involving manufacturing towards order (TMO) to assembling towards order (MMO).
In order to make this possible a semi-manufactured storage will be introduced after the standard confection which will represent the new decoupling point. The production at the standard confection will then occur according to the semi-manufactured storage. The standard confection should produce in larger aggregated order quantities based on prognosis in order to benefit from the advantages of economy of scale and the production must proceed in a continuous flow according to the FIFU-system (First In First Out). In addition to that, the special confection must produce according to a pull-system and only when the customer makes a request.
The tact-time of the GS products should constitute a limit for all the cycle times along the production chain, both on the standard- and special confection. This is partly due to creating a constant and balanced production flow which enables short through-put-time and partly due to avoiding in-between-storage as a result of various bottlenecks.
Labie, Christophe. "Etude du mode d'action de dicB, inhibiteur de division : produit du gène dicB d'Escherichia coli." Toulouse 3, 1990. http://www.theses.fr/1990TOU30042.
Full textBeltrame, Vilma. "Qualidade de vida de idosos diab?ticos." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2008. http://tede2.pucrs.br/tede2/handle/tede/2581.
Full textA avalia??o da qualidade de vida est? alicer?ada na percep??o do indiv?duo de sua posi??o na vida no contexto da cultura e sistema de valores nos quais ele vive e em rela??o aos seus objetivos, expectativas, padr?es e preocupa??es. Diante desta perspectiva, este estudo teve como objetivo estudar a qualidade de vida dos idosos com diabetes mellitus (DM), atrav?s dos instrumentos WHOQOL-BREF e o WHOQOL-OLD. Para isto foi realizado um estudo observacional, descritivo e anal?tico do tipo corte transversal com 50 idosos diab?ticos e 50 idosos n?o diab?ticos que freq?entavam grupos de idosos do munic?pio de Conc?rdia SC. A amostra foi composta por 68% de idosos do sexo feminino e 32% do sexo masculino. As idades variaram de 60 a 83 anos, com uma m?dia de 68,7?5,1 anos. Entre os idosos n?o diab?ticos a m?dia de idade foi de 68,7 anos e entre os diab?ticos de 69,0 anos. Em rela??o ao grau de instru??o 40% dos idosos sem DM e 29% dos idosos diab?ticos tinham de 1 a 4 anos de estudo. Entre os idosos diab?ticos 47% possu?am outro problema de sa?de. A hipertens?o arterial atingia 47% deles e problema de cora??o 13%. Somente 10% dos idosos com DM referiram seguir a dieta prescrita e 92% referiram tomar a medica??o prescrita corretamente. O resultado do escore da avalia??o geral da qualidade de vida do WHOQOL-BREF foi de 73,5 ? 12,5 entre os idosos sem DM e de 66,2 ? 13,6 entre os idosos com DM (p=0,007). O escore total do WHOQOL-BREF foi de 78,6?8,1 para os idosos sem DM e de 73,8?9,5 para os idosos diab?ticos (p=0,008). No instrumento WHOQOLOLD o escore geral para os n?o diab?ticos foi de 79,6 ? 7,4 e para os diab?ticos foi de 76,0 ? 11,5 n?o havendo signific?ncia estat?stica entre os dois grupos. Nas facetas participa??o social e intimidades houve diferen?a estatisticamente significativa, (p=0,003) e (p=0,034), respectivamente, com menor percep??o para os idosos diab?ticos. A avalia??o do n?vel de qualidade de vida dos idosos com DM ? diferente quando comparado ao dos idosos sem DM. O escore total do instrumento WHOQOL-BREF e do WHOQOL-OLD tiveram uma menor percep??o entre os idosos com DM.
Trentin, Cristiani Silveira Netto. "Ades?o medicamentosa em pacientes idosos diab?ticos." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2009. http://tede2.pucrs.br/tede2/handle/tede/2592.
Full textA popula??o mundial e brasileira est? envelhecendo, tornando-se importante considerar os v?rios aspectos que acompanham o envelhecimento, entre eles as mudan?as fisiol?gicas e as doen?as comumente verificadas no paciente idoso. O diabetes mellitus tipo II, muito comum nessa faixa et?ria, provoca, muitas vezes, ao longo do tempo, um aumento da glicemia, levando ? necessidade de uso de medicamentos e contribuindo para uma situa??o de polifarm?cia. Por isso a import?ncia de uma conduta correta do paciente com a terapia medicamentosa, para que o avan?o da doen?a seja retardado. Um dos problemas existentes ? a falta de ades?o ao tratamento. O objetivo desse trabalho ? verificar as mais diversas vari?veis que possam interferir no controle do diabetes mellitus em idosos. Para isso, foram utilizadas duas amostras populacionais, uma advinda do Estudo Multidimensional dos Idosos de Porto Alegre (EMIPOA), realizado no Instituto de Geriatria e Gerontologia (IGG) da Pontif?cia Universidade Cat?lica do Rio Grande do Sul (PUCRS). Nessa amostra foram analisadas vari?veis s?cio-demogr?ficas, cl?nicas e referentes a dieta habitual, comparando com os dados de ades?o obtidos atrav?s de um question?rio autorelatado. A segunda amostra foi composta por um grupo de idosos diab?ticos que participaram de um ensaio cl?nico para verificar a efic?cia do Projeto Emprego da Constru??o do Conhecimento em um Plano de Interven??o Farmac?utica para Promover a Ades?o ? Prescri??o de F?rmacos Hipoglicemiantes em Idosos. Foi tamb?m um estudo transversal onde apenas os dados coletados antes da interven??o foram utilizados. Esse projeto analisou a ades?o atrav?s de question?rio de auto-relato e contagem de comprimidos esquecidos. Foram analisadas vari?veis s?cio-demogr?ficas, farmacol?gicas, cl?nicas, cognitivas e as estrat?gias de mem?ria utilizadas pelos idosos para tomar a medica??o. Os resultados obtidos mostram que existe influ?ncia da faixa et?ria sobre a ades?o, por?m, ao contr?rio do que se imagina, a mesma melhora com a idade. Assim como o n?mero de medicamentos, que aumenta com o aumento da frequ?ncia de idosos aderentes. Outra quest?o interessante ? a rela??o das estrat?gias de mem?ria com a pontua??o no question?rio de ades?o, e tamb?m podemos perceber uma diminui??o no consumo de carboidratos pelos aderentes, sugerindo uma ades?o tamb?m ? dieta. Com estes resultados podemos desenvolver estrat?gias que possam melhorar a ades?o medicamentosa nessa popula??o.
Chuang, Chien-Kuo Eric. "DIB on the Xerox workstation /." Online version of thesis, 1986. http://hdl.handle.net/1850/8856.
Full textOliveira, Adriano Quilião de. "Síntese de vistas em depht-image-based rendering (DIBR)." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/143155.
Full textThis dissertation investigates solutions to the general problem of generating synthetic views from a set of images using the Depth-Image-Based Rendering approach. This approach uses a compact format for the 3D image representation, composed basically of two images, one color image for the reference view and other grayscale image with the disparity information available for each pixel. Solutions to this problem benefit applications such as Free Viewpoint Television. The biggest challenge is filling in regions without projection information considering the new viewpoint, usually called holes, and other artifacts such as cracks and ghosts that occur due to occlusions and errors in the disparity map. In this dissertation we present techniques for removal and treatment of each of these classes of potential artifacts. The set of proposed methods shows improved results when compared to the current state of the art generation of synthetic views using the DIBR model applied to the Middlebury dataset, considering the SSIM and PSNR metrics.
Smith, D. "Universalisme dans l'oeuvre de Mohammed Dib." Thesis, Swansea University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639075.
Full textDiab, Yasser Velex Philippe Ville Fabrice. "Analyse des pertes de puissance dans les transmissions par engrenages à grande vitesse applications aux réducteurs industriels et aux machines textiles /." Villeurbanne : Doc'INSA, 2005. http://docinsa.insa-lyon.fr/these/pont.php?id=diab.
Full textNordkvist, Johannes. "Depth-Aware Preprocessing for Reducing Viewer Discomfort in DIBR Systems." Thesis, KTH, Ljud- och bildbehandling, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-55366.
Full textSanson, Hervé. "Le témoin littéraire : réécriture chez Mohammed Dib." Paris 8, 2005. http://www.theses.fr/2005PA082624.
Full textThe literary witness would be the name of a textual device when it does not sacrifice the testimonial injunction. How, when one is an Algerian writer of French language, to sign a singular language, a poetic experiment of the language, without giving up attesting event-referents, standing as guarantor of a extradiegetic reality ? The literary witness Mohammed Dib testifies initially by a memory to the texts and forging will since confabulated a witness of artifice, succeeding the golden age of testimony. The literary witness would be this quite real aporia, instituting a new order of believing and asking for a responsible reader who answers about it. A witness who asks the impossible one. Who since the wound of the event tames the catastrophe, gives him form, informs it because it goes there from the literature in its oath to the other
Benkelfat-Benmansour, Sabiha. "L'ancrage tlemcénien de l'œuvre de Mohammed Dib." Montpellier 3, 2007. http://www.theses.fr/2007MON30012.
Full textDefinitely modern and part of a universalistic orientation, the work of art of the Algerian novelist Mohammed DIB is deeply rooted in its cultural context. Tlemcen, his native town of a rich sociocultural past, and “his first space of writing”, had been his first characterized area of inspiration to his reading to the world and the basis of his sensibility and his literary creative production. Determined by this heritage, Dib, in his turn, marked this notion of Tlemcenian intellectuality through “the other’ language”. It is an all “way of being”, deeply felt in his writings that let superficially touch the writer’s impact of a dynamic existing fact. Exemplified through different piece of writings, either from these first works of art or those which will come, the analysis, undergone through that implicit or explicit omnipresence, refers to the Dibien discourse relationship with those varieties which surround him and mainly related to those forms pictorizing this spirit of his historical and sociocultural background. Considering as well as the relationship with alterity, this analysis is perceived a new layer of multiplicity of “un déjà là” lived and assumed by the novelist as new window to life. This study shows that if Tlemcen in Dib’s search, pursuing an essential truth of the world and as a landmark always to which he refers back, is an escaped point, usually displaced, turns to be a metaphorical expression. Tlemcen, an ethnic identity marker, but also a place of observation and affirmation of general values brings to that Tlemcenian discourse a universalistic trend
Assis, Ang?lica Oliveira de. "Avalia??o cl?nica da resposta do tratamento periodontal n?o-cir?rgico (Full mouth desinfection) de pacientes diab?ticos e n?o diab?ticos." Universidade Federal do Rio Grande do Norte, 2012. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17826.
Full textTem sido demonstrado que o diabetes influencia no desenvolvimento e progress?o da doen?a periodontal. Acredita-se ainda que h? uma rela??o bi-direcional entre o Diabetes Mellito e a Doen?a Periodontal. Por isso, o tratamento periodontal pode responder de forma diferente em pacientes com e sem o quadro de diabetes. O objetivo desse estudo foi avaliar clinicamente o efeito da terapia periodontal n?o cir?rgica em pacientes com periodontite e diabetes mellito (grupo teste) e sem o quadro de diabetes (grupo controle). Para isso, realizou-se o tratamento periodontal n?o-cir?rgico FMSRP (Full mouth Scalling and Root Planing) e verificou-se os par?metro cl?nicos periodontais (profundidade de sondagem, n?vel cl?nico de inser??o, mobilidade, ?ndice gengival e ?ndice de placa) no in?cio do estudo e ap?s 3 meses. Na an?lise estat?stica, o paciente foi considerado como unidade de an?lise (p<0,05). Para as vari?veis categ?ricas utilizou-se o teste de Fisher. Nas compara??es inter-grupo, foi utilizado o Mann-Whitney Test e para compara??es intra-grupo (baseline e tr?s meses) utilizou-se o Teste de Wilcoxon. Participaram 26 pacientes no grupo controle e 14 no grupo teste. O ?ndice de placa era 71,20% no in?cio do estudo para o grupo teste e ficou 47,12% no fim; j? no controle, os valores eram de 48,52% passando para 37,50%. E o ?ndice gengival no grupo teste no baseline era 42,67 diminuindo para 26,81 e no grupo controle diminuiu de 41,36 para 30,62. A profundidade de sondagem foi no grupo teste 2,71mm passando para 2,40mm; j? no controle, os valores foram de 2,84mm diminuindo para 2,55mm. O grupo controle ganhou 0,34 mm de inser??o e o grupo teste perdeu 0,44mm de inser??o. A recess?o gengival aumentou 0,33mm no grupo teste e 0,04mm no grupo controle ap?s os 3 meses. Houve diferen?a significativa inter-grupo para o ?ndice de placa e gengival no baseline, tamb?m foi encontrado na recess?o ap?s 3 meses; j? intra-grupo verificou-se diferen?a significativa para todas as vari?veis, exceto para o n?vel clinico de inser??o e mobilidade. Quando se categorizou a profundidade de sondagem em ≤3mm, >3 e≤6mm e >6mm, n?o foi encontrado diferen?a entre os grupos, mas verificou-se diferen?a significativa entre os per?odos tanto para o grupo teste como para o controle. A hemoglobina glicada no grupo controle foi de 5,90% e no teste aumentou de 7,79% para 8,10%. Portanto, verifica-se que h? uma melhora dos par?metros cl?nicos periodontais em ambos os grupos, contudo n?o se verificou uma diferen?a significativa entre eles. N?o obstante, o FMSRP promove um efeito ben?fico em rela??o ? condi??o de sa?de periodontal, melhora dos par?metros cl?nicos periodontais, em curto prazo (3 meses) tanto em indiv?duos diab?ticos como em n?o diab?ticos, n?o sendo poss?vel observar um melhor quadro glic?mico nos diab?ticos
Arancibia, María de las Victorias. "Un estudio sobre la traducción de los fraseologismos en El DiBU." Florianópolis, SC, 2007. http://repositorio.ufsc.br/xmlui/handle/123456789/90383.
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El presente estudio tiene como objetivo analizar fraseologismos a través de 21 expresiones idiomáticas en la dirección portugués-español del Diccionario Bilingüe de Uso Español-Portugués / Português-Espanhol (DiBU), con la pretensión de verificar la equivalencia y la adecuación de sus traducciones. Esta verificación se ha realizado a partir del análisis de los aspectos morfosintáctico, semántico, de registro y de frecuencia de uso de las mismas. De esta forma se pretendió confirmar los presupuestos sobre las dificultades en el hallazgo de equivalencias en la traducción de la fraseología, la existencia de equivalentes, en la lengua meta, y su inclusión en los diccionarios bilingües. Se han utilizado como herramientas un corpus de la UFSC y el sistema de búsquedas Google. Los análisis realizados con base en los datos encontrados confirman la adecuación de las traducciones y la existencia de equivalencias parciales entre la lengua portuguesa y la lengua española en el diccionario citado.
Santos, Maria Gorete Bender dos. "Análise de exemplos no Diccionario Bilingüe de Uso Portugués-Español (DIBU)." Florianópolis, SC, 2006. http://repositorio.ufsc.br/handle/123456789/103157.
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A presente pesquisa tem por objetivo analisar os exemplos em português de oito substantivos e oito adjetivos do Diccionario Bilingüe de Uso Español-Portugués Portugués-Español (DiBU), com o intuito de verificar se estes exemplos refletem de fato o uso real da língua portuguesa. Esta verificação foi realizada a partir da freqüência encontrada de trechos dos exemplos no site de buscas Google. Desta forma pretendeu-se confirmar a informação fornecida pelos autores do DiBU de que os exemplos desse dicionário foram baseados no uso real da língua portuguesa. Foram pesquisadas também quais as colocações encontradas com estes substantivos e adjetivos visando apresentá-las como sugestões para possíveis exemplos nos dicionários. No caso dos substantivos foram pesquisados também quais os verbos que geralmente os acompanham. Estas buscas foram realizadas no corpus da Folha de São Paulo, 1995/1996. As análises realizadas com base nos dados encontrados confirmam que a maioria dos exemplos pesquisados de fato reflete o uso real da língua portuguesa.
El, Yajouri Meriem. "Diffuse Interstellar Bands (DIBs) : a new look at an old problem." Thesis, Paris Sciences et Lettres (ComUE), 2018. http://www.theses.fr/2018PSLEO017/document.
Full textDiffuse interstellar bands (DIBs) represent a century-old mystery: none of the hundreds of bands could be identified with certainty with a specific carrier, at the very likely exception of the buckminsterfullerene cation C60+. Identifying and quantifying the amount of the large interstellar carbonaceous molecules that are very likely responsible for the DIBs is mandatory: DIB carriers likely represent the largest amount of organic matter in the Universe and are an important piece of the chain of processes that govern the interstellar/stellar cycle.Up to recently, most of the DIB studies have had as a unique goal the identification of the carriers, and to do so have been focusing on a limited number of hot, distant and reddened stars, using increasingly powerful instruments. This thesis marks a turning point in the methods and goals associated with the DIBs, an evolution allowed and motivated by the increasing number of stellar surveys with high multiplex instruments. As a matter of fact, it is possible today to gather massive amounts of data, both from the point of view of the number of target stars and from the point of view of the number of DIBs simultaneously observed. This has opened the way to new types of studies, more ambitious goals, and, importantly, new potential comparisons with laboratory data. This thesis presents a large number of DIB extractions and four of these novel analyses :- Methods of extraction and search for new DIBs.- Statistical studies of the link between DIB strengths and the physical properties of their hosting clouds.- Tomographic studies of the carriers on large and small spatial scales.- Line profile extractions based on carefully selected sightlines, studies of their substructures and spatial variability and subsequent constraints on their potential molecular carriers
Boulafrad-Abudura, Fatiha. "Topique colonialiste et contre-topique dans la trilogie Algérie de Mohammed Dib." Lille : ANRT. Atelier national de reproduction des thèses, 2008. http://catalog.hathitrust.org/api/volumes/oclc/231579992.html.
Full textCampbell, Madeleine. "Translating Mohammed Dib : Deleuzean rhizome or Sufi errancy?" Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/5105/.
Full textClark, Colin. "Cross-cultural poetics in Kateb, Salih, Djebar and Dib." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:436b2243-7b55-4f4c-9c61-6ce94f1ca300.
Full textKhlifi, Mohammed. "Les terrasses d'Orsol de M. Dib : écriture et intertextes." Paris 13, 1997. http://www.theses.fr/1997PA131011.
Full textThe terraces of orsol by m. Dib is a perfect example of the works that go beyond the mere themes of identity assertion and denunciation characterising pre-indepence literature. When reading the terraces of orsol, one, indeed, encounters some universal works such as samuel beckett's, in molloy for example, dino buzzati's in the desert of the tartars, and especially julien gracq's in the schore of syrts that bears striking similitudes with did's novel. Likewise the narrative of the book is a crossroads of various cultural fields, for instance, the nietzschian hypotext which is very called upon to underscore the relationship binding words and the theme of the eternal return : is not naming a call for coming, a call that recommends ? is not wrinting subjected to this "re" of return ? does not the writer, when performing his act again, ask about the being of his art's presence ? the answer to these questions could be summed up in this alternative : to write so as to never stop writing, to stop writing so as to never finish with writing. This concept then is that of solitude and confusion of the writer who tries to put up to words in a double way : first by producing infinitely the text and then by interrupting it to bring it to perfection ; in fact this goes on through all his life. Furthermore, the writing i lets itself be caught in a tragic game of roles where it is both actor and observer, the space-time of this game is ambivalent, structured and open upon a somewhere full of promises. Likewise this space-time claims to belong to a carnivalesque universe where the writing i finds itself snared in its own game : elevated, degraded, and sacrificed as a scapegoat in a society on the way to downfall and in favour of a sudden emergence of the last dibian man with the objective of violating this space and reaching anything else
Nait, Ouslimane Karim. "Etude de l’espace dans l’oeuvre romanesque de Mohammed DIB." Thesis, Paris 13, 2019. http://www.theses.fr/2019PA131077.
Full textThe notion of space in literature is not limited to the only spatial reference that places the literary text in a given context. In the fictional work of Mohammed Dib, space is itself at stake of a deterritorialized writing that often blurs the spatial references to leave the beaten track of the literature of the "Masters" and escape the"common places" of the literature French. A delicate literary equation that finds a happy solution in Dib's novelistic work under the Deleuzian sign of "becomingminor". All the work of Dib is crossed by a powerful desire of life which characterizes its main characters with tormented consciences. Thus, the little Omar is haunted by a constant hunger which is not that of the hungry belly but that of the Man deprived of freedom and who ends up joining the ranks of the militants for thein dependence of Algeria. Whether on the desert stretches of the Algerian Sahara or on the Scandinavian forests and lakes of the Nordic trilogy, the literary work of Mohammed Dib offers a privileged space for the interrogating man of the world whoreads, who writes to know himself
Lima, Val?ria Morgiana Gualberto Duarte Moreira. "Rela??o entre estresse oxidativo e oesteopenia diab?tica em ratas pr?-menopausadas." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13206.
Full textFunda??o de Amparo a Pesquisa do Estado de S?o Paulo
The relationship between lipid peroxidation, antioxidant defense and diabetic osteopenia remains unclear. This study evaluated the relationship between lipid peroxidation index, antioxidant defense parameter and bone metabolism in a premenopausal diabetic model by measurements such as thiobarbituric acid-reactive substances concentration (TBARS) and reduced glutathione (GSH) content in brain homogenates, histomorphometric analysis, biomechanical testing and bone mineral density (BMD). Female Wistar rats with regular estrous cycle were divided into two groups: Group 1: control rats (n = 15) and Group 2: diabetic rats (n = 15). Diabetes mellitus was induced by alloxan and confirmed by glycemia 250 mg/dL. The experimental period understood 1 and 5 after days induction and 45, 75 and 120 days after the installation of diabetes mellitus.The lipid peroxidation index, measured by TBARS concentration, showed a significant increase (p<0.05) in diabetic animals in comparison to animals control. However, the antioxidant parameter, measured by GSH content, was significantly decrease (p<0.05) in diabetic animals. Histomorphometric analysis showed a significant increase (p<0.05) in femoral trabecular separation together with a significant decrease (p<0.05) in trabecular thickness and reduced trabecular bone volume in diabetic rats. Moreover, biomechanical testing and BMD values were significant decrease (p<0.05) in diabetic group. Thus, our results demonstrated that increased lipid peroxidation and altered antioxidant defense could be related to the development of oxidative stress and diabetic osteopenia in premenopausal rats
A rela??o entre peroxida??o lip?dica, defesa antioxidante e osteopenia diab?tica permanece obscura. Este estudo avaliou a associa??o entre ?ndice de peroxida??o lip?dica, par?metro de defesa antioxidante e metabolismo ?sseo em um modelo diab?tico pr?-menopausado atrav?s de medidas como a concentra??o de subst?ncias reativas ao ?cido tiobarbit?rico (SRAT) e conte?do de glutationa reduzida (GSH) no homogenato cerebral, an?lises histomorfom?tricas, teste biomec?nico e densidade mineral ?ssea (DMO). Ratas Wistar com ciclo estral regular foram distribu?das em dois grupos: Grupo 1 - ratas controle (n = 15) e Grupo 2 - ratas diab?ticas (n = 15). O diabetes mellitus foi induzido pela aloxana e confirmado pela glicemia 250 mg/dL. O per?odo experimental compreendeu 1 e 5 dias ap?s a indu??o e 45, 75 e 120 dias ap?s a instala??o do diabetes mellitus. O ?ndice de peroxida??o lip?dica, medido pela concentra??o de SRAT, demonstrou um aumento significativo (p<0.05) nos animais diab?ticos, em rela??o aos animais controle. Entretanto, o par?metro de defesa antioxidante, mensurado pelo conte?do de GSH, foi reduzido significativamente (p<0.05) nos animais diab?ticos. As an?lises histomorfom?tricas mostraram um aumento significativo (p<0.05) da separa??o trabecular do f?mur, associado ? diminui??o significativa da espessura trabecular (p<0.05) e volume ?sseo trabecular reduzido nas ratas diab?ticas. Al?m disso, o teste biomec?nico, medido pela for?a m?xima de compress?o, e valores de DMO foram reduzidos significativamente (p<0.05) no grupo diab?tico. Dessa maneira, nossos resultados demonstraram que a peroxida??o lip?dica aumentada e defesa antioxidante modificada podem estar relacionadas ao desenvolvimento do estresse oxidativo e osteopenia diab?tica em ratas pr?-menopausadas
Matias, Luciana Corrêa. "Expressões idiomáticas corporais no Diccionário Bilingüe de Uso Espanhol-Português/Português-Espanhol (DiBU)." Florianópolis, SC, 2008. http://repositorio.ufsc.br/xmlui/handle/123456789/91019.
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Esta dissertação consiste no estudo de dez expressões idiomáticas (EIs) corporais inseridas no volume español-portugués do Diccionario Bilingüe de Uso Español-Portugués Português-Espanhol (DiBU). Objetivou-se verificar se essas EIs, tanto na língua espanhola quanto na tradução ao português, refletem o uso real, uma vez que o dicionário é denominado de uso. Além disso, foi investigada a hipótese de variações das EIs. Esta verificação foi realizada a partir da freqüência coletada no site de buscas Google e do estudo do contexto de uso com auxílio do corpus da Folha de São Paulo, 1997/1998. As EIs foram classificadas segundo os seguintes critérios de representatividade do uso: E representativa, E parcialmente representativa e E com representatividade nula. As análises realizadas com base nos dados coletados indicam que 10% das dez EIs pesquisadas em língua espanhola foram consideradas representativas e 90%, parcialmente representativas. As EIs inseridas como tradução, por sua vez, obtiveram 80% de representatividade e 20% de representatividade parcial. Em nenhuma das direções foram encontradas E com representatividade nula.
Capitanio, Letizia. "La bande interstellaire diffuse "GAIA" : optimisation de son extraction et de son utilisation à double but stellaire et interstellaire." Thesis, Paris Sciences et Lettres (ComUE), 2018. http://www.theses.fr/2018PSLEO007/document.
Full textThe Interstellar Medium (ISM) represents a small fraction of the Milky Way matter, but it plays a fundamental role because it governs the galactic evolution and its structure.Most of the ISM gaseous constituents have been identified through their emission or absorption characteristics, however, the "diffuse interstellar bands" (or DIBs), still has no counterpart in absorbing species.A favourable situation is the presence of a DIB (with central wavelength 862 nm) within the spectral interval of the Radial Velocity Spectrometer (RVS), one of the instruments of the ESA Gaia mission. The first part of the work presented in this document is directly related to the construction of this future catalog and its potential use.I have developed a profile fitting code adapted to the emph{Gaia} DIB and to the RVS instrument. I estime in my thesis how many DIBs will be measured.The second part of this thesis is related to the three-dimensional (3D) mapping of the ISM. I made the first tomography based on composite data, both extinctions and DIBs and showed this is a viable way. I ran parallel inversions of two extinction and DIB datasets for the same target stars and compared the distributions.The full 3D tomographic inversion technique in this case requires an unrealistically large computing time. I have developed a technique and I have applied it to a new catalog of 30 millions of extinction measurements based on Gaia.Finally, I used ground-based stellar spectra to extracted radial velocities and columns of IS absorbing species and participated to the first step of a "kinematic" 3D map of the ISM
Sari-Mostefa, Kara Fewzia. "Pouvoirs de l'écriture et authenticité : essai sur l'oeuvre de Mohammed Dib." Montpellier 3, 1986. http://www.theses.fr/1986MON30046.
Full textTo comprise the work of Mohammed Dib, in its real dynamics, we put the text to an evaluation with relevant linguistic tests. We obtain several readings which represent a first step to a essay of an inclusive reading of the engagement writings (1952-1959) and the desire poetics (1959-1980) of the algerian author. To understand the work, to analyse its constitutives elements, to reveal its laws, it is to appraise finally its rigour and its beauty
Diba, Anastasia Kena [Verfasser]. "Synthese von Chlorotonil A Derivaten und Untersuchungen zur stereoselektiven intramolekularen Protonierung / Anastasie Kena Diba." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover, 2010. http://d-nb.info/1008410349/34.
Full textCopetti, Caroline Eickhoff. "Anticorpos anticardiolipina : preval?ncia em diab?ticos com e sem eventos vasculares pr?vios." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2011. http://tede2.pucrs.br/tede2/handle/tede/1612.
Full textA rela??o entre anticorpos anticardiolipina (aCL), marcadores da s?ndrome antifosfol?pide, e vasculopatia em diab?ticos ? mat?ria de debate. Este estudo, transversal controlado, avaliou a freq??ncia de IgG, IgM e IgA aCL em diab?ticos do tipo 2 com ou sem eventos vasculares nos ?ltimos 5 anos e em controles sadios. Os anticorpos foram detectados por ensaio imunoenzim?tico. Setenta e tr?s diab?ticos (33 com eventos vasculares pr?vios) e 54 controles foram estudados. Diab?ticos foram predominantemente mulheres (p=0,003), e de idade mais avan?ada (p<0,001) em rela??o aos controles. A dura??o m?dia da doen?a foi de 10 anos. A preval?ncia de teste positivo para anticorpos aCL foi de 7,4% em controles e de 9,5% em diab?ticos (p=0,910). Ap?s ajuste para sexo e idade, a freq??ncia de anticorpos aCL n?o diferiu significativamente quando se comparou controles e diab?ticos com ou sem macrovasculopatia (p>0,09). A freq??ncia de anticorpos aCL tamb?m n?o diferiu quando se comparou os dois grupos de diab?ticos entre si (p>0.47). Ap?s ajuste para sexo, idade, hipertens?o e tabagismo, uma associa??o fraca, mas estatisticamente insignificante, foi 28 observada entre IgM aCL e diab?ticos com vasculopatia (OR ajustado 2,7; IC95% 0,2-34,2; p=0,441). Globalmente, n?veis de IgG (r=0,25; p=0,005) e IgM (r=0,23; p=0,010) aCL se correlacionaram com idade progressiva. Em resumo, a freq??ncia de teste positivo para anticorpos aCL em diab?ticos tipo 2 (com ou sem hist?rico vascular) n?o foi significativa em rela??o a controles sadios. N?o houve associa??o entre presen?a de anticorpos aCL e eventos vasculares em diab?ticos tipo 2.
Bento, Rita Costa San Miguel. ""Proposed Management Plan For Rul Dibba - Al Faqeet Marine Protected Area, Fujairah Emirate, UAE"." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2008. http://hdl.handle.net/10216/18652.
Full textBento, Rita Costa San Miguel. ""Proposed Management Plan For Rul Dibba - Al Faqeet Marine Protected Area, Fujairah Emirate, UAE"." Dissertação, Instituto de Ciências Biomédicas Abel Salazar, 2008. http://hdl.handle.net/10216/18652.
Full textMao, Dun. "A quality assessment approach and a hole-filling method for DIBR virtual view images." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3950633.
Full textAdjil, Bachir. "Espace, imaginaire et écriture dans la trilogie nordique de Mohammed Dib." Paris 8, 1992. http://www.theses.fr/1992PA080756.
Full textIs there an esoteric sense in the "Trilogie nordique", of Mohammed Dib? From the hermeneutic analysis of his three novels, it clearly appear that the author uses a Gnostic writing. Langage is questioned through a silent talk ( unareasable mark of his proper lack to the expressivity, a representation directly considered as a negativity etc. . . The unspeakable seems to be embodied himself within the things to replace the names, wich create a referential lack by their absence. Then the imperceptible reign over the text to allow transcendency, the writing turns into a mystical interrogation
Simon, Rachida. "La poétique "du liseron épineux", mystique et écriture chez Mohammed Dib." Paris 3, 2002. http://www.theses.fr/2002PA030095.
Full textThe main objective set to this work in the analysis of Mohammed DIB's last novels in the light of a thought which is used as an ethical and aesthetic foundation to the text: Ibn Arabi's thought, which advocates an Essential Islam, and whose contribution to art and literature in Moslem countries as well as in Western counties has been fundamental. Strongly marked by the emblematic character of Cheikh El Akbar, the "Dibian" writing, when attempting to reconciliate the Orient and the Occident in a generous attitude of opening onto the Other, ends in a real rhapsody and announces the advent of a new humanism. In the present context of internationalisation and communication where everyone is required to discuss and live with the others, this visionary writing wants to be a message of love for a better world: an act of knowledge and an act of love represented by this singular spiralling figure of the trope iltifât. Found in the Arab pre-Islamic poetry as well as in the Coran where it is extensively used, but also used as the emblem and the attribute to Hermes, this figure of the intertwining of the 'Liseron Epineux', present everywhere in the Islamic art, is analysed in this work as the figure and the key to DIB's last novels. This figure of the spiral, the twist, affects all the levels in the text and imposes itself as being the mark of the Maghreban writer in his privileged but uncomfortable insular position. It deeply marks a writing where modernity and tradition are intimately mixed, and where an essential space of conviviality and humanism between the two cultures is opened in a dynamic and generous attempt of moving from the matter to the spirit
Sari-Mostefa, Kara Fewzia. "Pouvoirs de l'écriture et authenticité essai sur l'oeuvre de Mohammed Dib." Lille 3 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb375998818.
Full textRemmal, Taoufik. "Etude métallogènique des indices wolframifères du district de Hassiane Diab, région d'Oujda (Maroc nord oriental)." Phd thesis, Institut National Polytechnique de Lorraine - INPL, 1989. http://tel.archives-ouvertes.fr/tel-00745438.
Full textChung, Hao-Feng [Verfasser], and Michael [Akademischer Betreuer] Pawlik. "„Der bestohlene Dieb“ — Diskussion über die Schutzgüter beim Diebstahl / Hao-Feng Chung ; Betreuer: Michael Pawlik." Regensburg : Universitätsbibliothek Regensburg, 2016. http://d-nb.info/1116080206/34.
Full textLoureiro, Melina Bezerra. "Estudo da associa??o dos genes RANk, RANKL e OPG com a osteopatia diab?tica." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br/handle/123456789/19413.
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Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES
Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico - CNPq
O objetivo do presente trabalho foi avaliar a express?o de RNAm e os polimorfismos dos genes RANK, RANKL e OPG de crian?as, adolescentes e adultos jovens com DM1, bem como estudar a associa??o dos mesmos com o desenvolvimento de altera??es no metabolismo ?sseo.No total, foram inclu?dos no estudo 119 crian?as e adolescentes com DM1 e 161 indiv?duos normoglic?micos (NG) da mesma faixa et?ria. Foram pesquisados os polimorfismos dos genes OPG (1181 G>C e 163 A>G), RANK (575 C>T e 3'UTR C>A) e RANKL (?ntron A>G) e determinadas as express?es g?nicas de OPG, RANK e RANKL. Al?m disso, foram avaliados o controle glic?mico e par?metros laboratoriais de fun??o ?ssea, al?m da densitometria ?ssea. Os indiv?duos com DM1 apresentaram um controle glic?mico insatisfat?rio e valores diminuidos de c?lcio total, propept?deo do col?geno tipo 1 (CTX), como tamb?m baixa densidade mineral ?ssea, quando comparados com os NG (p<0,05). O polimorfismo OPG 1181 G>C pode estar associado com susceptibilidade ao DM1 (p=0,054). Estudando apenas os indiv?duos com DM1, foi observado que os carreadores do gen?tipo OPG 1181 GG apresentaram maiores concentra??es de c?lcio ionizado no modelo recessivo (p<0,05). Esses resultados sugerem que o polimorfismo OPG 1181 G>C pode contribuir para o desenvolvimento do DM1 e da osteopatia diab?tica.
Cam, Kaymeuang. "Étude de l'opéron dicB impliqué dans le contrôle de la division cellulaire chez Escherichia Coli." Paris 11, 1987. http://www.theses.fr/1987PA112016.
Full textCam, Kaymeuang. "Etude de l'operon dicB impliqué dans le contrôle de la division cellulaire chez Escherichia coli." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37603573p.
Full textLičko, Stanislav. "Konferenční a žurnálový redakční systém s modulární architekturou." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2013. http://www.nusl.cz/ntk/nusl-220091.
Full textBoulafrad-Abudura, Fatiha. "Topique colonialiste et contre-topique dans la "trilogie Algérie" de Mohammed Dib." Montpellier 3, 2004. http://www.theses.fr/2004MON30031.
Full textIn this trilogie "ALGERIE", Mohammed DIB, french_speacking_Algerian writer invests the colonialist topics in order to assert a think as negate it. He asserts in order to use it and work it on again in bi-cultural language : Arabic and French. The colonialist topics are thus emptied then reloaded by a transversal rhethorical effect partaking together of a western irony and an Arabic stylistics called el adhad
Chaabene, Rached. "La réverbération de l'Histoire dans des nouvelles de Kessel, Camus et Dib." Thesis, Nice, 2016. http://www.theses.fr/2016NICE2013.
Full textThe historical narratives attached to this period were mainly marked by hybridity. They oscillate between the biographical and autobiographical, fact and fiction, the individual and the collective, and the current and the universal. They immersed into the themes of anguish and death, reverberating the human condition. In this vein, the novella of twentieth century sounds reflecting this new perception of history. It is a protean genre that offers a more flexible narrative framework involving altogether referential, poetic, symbolic and universal scopes of writing.Kessel, Camus and Dib go beyond mere obsession with a specific period to provide a more personal view of history. To this end, they reshape the historical discourse and its ideologies, translating them with, by and in their fictional texts. They disrupt the chronology, linearity and totality
Sousa, Maria Goretti de Menezes. "Estudo cl?nico das manifesta??es orais e fatores relacionados em pacientes diab?ticos tipo 2." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13305.
Full textConselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico
Estudo transversal com o objetivo de identificar a preval?ncia de altera??es dos tecidos moles orais em pacientes portadores de Diabetes Mellitus (DM) tipo 2, utilizou-se a an?lise de vari?veis socioecon?micas, g?nero, hereditariedade, glicose capilar e fatores locais como uso de pr?tese e sensa??o de boca seca. A amostra constou de 196 pacientes diab?ticos e n?o-diab?ticos, arrolados do HIPERDIA em 41 Unidades da Rede B?sica de Sa?de na cidade de Natal-RN-Brasil. Os resultados encontrados para a ?ltima glicemia sangu?nea entre os diab?ticos teve m?dia de 177,0 mg/dl, e entre os n?o diab?ticos foi de 89,46 mg/dl; a glicemia capilar dos diab?ticos estava com m?dia elevada no valor de 215,95 mg/dl; enquanto que entre os n?o-diab?ticos foi de 102,31mg/dl. A presen?a da DM tipo 2 e a an?lise para o hist?rico familiar confirmou a hereditariedade da doen?a com 68,8% pacientes diab?ticos (n=66) (p<0,001), o grau do parentesco pelo pai ou m?e com 59,7% dos pacientes(n=40). A hipertens?o estava presente entre os dois grupos e o uso do tabaco teve resultado favor?vel ao abandono do uso do mesmo entre os grupos; a preval?ncia de fluxo salivar baixo nos diab?ticos foi de 49% (n=47) e nos pacientes n?o diab?ticos de 34% (n=34). A presen?a de candid?ase foi de 30,5% nos pacientes diab?ticos e nos pacientes n?o diab?ticos foi de 36%, sem significado estat?stico (p=0,23). As les?es encontradas situavam-se no palato para os dois grupos em 81,4% dos pacientes diab?ticos (n=35) e 71,1% dos pacientes n?o diab?ticos (n=27) (p=0,68). As altera??es orais encontradas n?o est?o relacionadas com a DM, que se apresentam independentes da presen?a ou n?o da DM tipo 2
Leetmaa, Benjamin. "En integration av betalningssystem på hemsida." Thesis, Högskolan i Gävle, Avdelningen för Industriell utveckling, IT och Samhällsbyggnad, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-11076.
Full textDiab, Hilal [Verfasser], Stefan [Akademischer Betreuer] Kowalewski, and Dirk [Akademischer Betreuer] Abel. "Experimental validation and mathematical analysis of cooperative vehicles in a platoon / Hilal Diab ; Stefan Kowalewski, Dirk Abel." Aachen : Universitätsbibliothek der RWTH Aachen, 2015. http://d-nb.info/113040269X/34.
Full textTAPE, BAROAN TINA GENEVIEVE. "Peinture sociale dans l'oeuvre romanesque de mohammed dib et d'ousmane sembene, ecrivains africains." Grenoble 3, 1998. http://www.theses.fr/1998GRE39005.
Full textMohammed dib and sembene ousmane in depicting their societies, have shown a rural and urban social environment whose organisation in two parts. European and indigenous ; reflects the opulence of the foreigners and the poverty of the indiginou people. Besides, the political and economic relationships observed, the rural exodus experienced, show that the countryside has lost its autonomy and attractive ness for the city. In the same way, the relationships between city-dwellers and rural folk reveal the mutual indifference or hostility which obstructs the struggle for national liberation. The two writers have depicted two communities one indigenous and the other european. Within the indigenous one, there are two antagonistic social classes, one which enjoys many privileges, lives in comfort, while the other leads a miserable and precarious life. These two classes have hostile relationships. Within this community some natives accept foreing domination because they believe in european superiority, others adapt to it and collaborate with the rulers, whilst others oppose the colonial system in various ways. Of all the forms of resistance, the best organised one is the strike of the fellahs in l'incendie or that of the railway workers in les bouts de bois de dieu. The europeans who have a great political and economic power, have conflictual relationships with the natives they exploit. By their personal life their experience of the colonial situation, and their various independence struggles, in the political as well as the literary field, mohammed dib and ousmane sembene were bound to describe their sicieties in order to contribute, like their contemporaries, to the liberation struggle. Furthermore, constantly concerned with informing and convincing the reader, they have shown an african space, drawn inspiration from historical events, described scenes and customs, and created characters conforming to people they know. In sum, we note that both writers have given the same image of the colonial society. This identical approach stems from the fact that their countries were subjected to the same european power. With their realist style, they have succeeded in giving an account of the situation in their countries and contributed to forming opinion which led to the algerian war in north africa in 1954 and to the political demands in west africa
Akaïchi, Mourida. "Quête et théâtralité à travers les romans de Mohammed Dib et Gassan Kanafani." Lyon 2, 2000. http://theses.univ-lyon2.fr/documents/lyon2/2000/akaichi_m_notice.
Full textThe works of Mohammed Dib and Gassan kanafani employ different kinds of artistic search as to objects, space, identity, emancipation. . . To translate the sense. This multiple search goes in line with theatrality which embodies representative and dramaturgical aspects of the novels. This study is an attempt to show how these appear and meet in the two writers' works
Akaïchi, Mourida Bonn Charles. "Quête et théâtralité à travers les romans de Mohammed Dib et Gassan Kanafani." Lyon : Université Lyon 2, 2000. http://demeter.univ-lyon2.fr/sdx/theses/lyon2/2000/akaichi_m_notice.
Full textSantos, Sara Dereste dos. "Influência da tensão mecânica (strain) no abaixamento de barreira induzido pelo dreno (DIBL) em FinFETs de porta tripla." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/3/3140/tde-12082010-124643/.
Full textThis work presents a study about the influence of strain in the drain induced barrier lowering effect (DIBL) in triple gate SOI FinFETs. Also it is analyzed the selective epitaxial growth used in that structures, comparing their behavior in relation to DIBL effect. Using the vertical multi-gate devices become possible the downscale whereas they present higher current level and suppressed short channel effects. However, reducing the channel width, the transistors total resistance increases and consequently its performance decreases. In order to improve this feature, the strained technology and the Source/Drains growth technique has been employed. In the first case, the mechanical deformation causes a change in the electron shell, which improves the carrier mobility. Consequently, the current level and the transconductance also improve. The selective epitaxial growth technique aims to reduce the devices total resistance since these regions areas increase, allowing large contacts which are responsible for the main parcel of the total resistance. This work is based on experimental results and tridimensional simulations that analyze the transistor behavior using the technologies above presented as a function of DIBL effect.
Barreto, Mardem Portela e. Vasconcelos. "Efeito da associa??o de laserterapia e pr?polis na cicatriza??o de feridas em ratos diab?ticos." PROGRAMA DE P?S-GRADUA??O EM BIOLOGIA ESTRUTURAL E FUNCIONAL, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/24334.
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Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES)
O diabetes mellitus causa uma s?rie de complica??es sist?micas, incluindo o retardo no processo de cicatriza??o. Diversas alternativas terap?uticas t?m sido testadas em estudos in vitro e in vivo para promover melhora no processo de reparo de feridas em animais e indiv?duos diab?ticos. O objetivo do presente estudo foi avaliar o efeito da associa??o da laserterapia de baixa intensidade com a administra??o t?pica de pr?polis verde em feridas cut?neas em ratos com diabetes induzida por estreptozotocina. Foram utilizados 90 animais, alocados nos seguintes grupos: (N) normoglic?micos (sem indu??o), sem terapia; (C) controle diab?tico, sem terapia; (L) submetidos ? laserterapia de baixa intensidade (660 nm, 30 mW, 4 J/cm2); (P) submetidos ? administra??o t?pica de pr?polis verde (extrato alco?lico a 30%); e (LP) submetidos ? combina??o de laserterapia com administra??o t?pica de pr?polis verde. Os procedimentos terap?uticos foram realizados a cada 24 horas, por 6 dias. As ?reas cir?rgicas foram fotografadas em dias intercalados, para avalia??o da ?rea de fechamento da ferida. Nos intervalos de 7, 14 e 21 dias parte dos animais foi submetida ? eutan?sia e posterior remo??o da ?rea da ferida. Os esp?cimes foram fixados, processados rotineiramente e inclu?dos em parafina e as l?minas obtidas foram coradas por H/E e Picrosirius red, para avalia??o da reepiteliza??o, intensidade do infiltrado inflamat?rio e forma??o e organiza??o de col?geno, al?m da imunomarca??o para FGF-2 e VEGF. Os dados quantitativos foram submetidos a testes estat?sticos n?o param?tricos, com intervalo de confian?a de 95%. A avalia??o macrosc?pica da ?rea da ferida mostrou que os tr?s grupos tratados (L, P e LP) exibiram uma acelera??o da retra??o da ferida em rela??o ao grupo C (p<0,001) a partir do 3? at? o 14? dia, com resultado semelhante ao grupo N. O grupo LP apresentou um melhor resultado em rela??o aos demais (p<0,05) a partir do 5? dia. A an?lise histol?gica mostrou que os grupos tratados exibiram maiores ?ndices de reepiteliza??o, especialmente nos grupos L e LP, e tamb?m menores ?ndices de inflama??o, com destaque para os grupos LP e P. Com rela??o ? propor??o col?geno I/III observou-se no 7? dia valores maiores no grupo LP em rela??o ao grupo C (p<0.05), assemelhando-se ao grupo N. No 14? dia o grupo L apresentou a maior propor??o dos grupos tratados, aproximando-se dos resultados do grupo N e com diferen?a estat?stica para os demais grupos experimentais (p<0,01). N?o houve diferen?a na propor??o col?geno I/III entre os grupos no intervalo de 21 dias. Os tr?s grupos tratados exibiram menor express?o de FGF-2 e VEGF em compara??o com os grupos N e C, especialmente o grupo LP (p<0,05). Em conjunto, os resultados do presente trabalho permitem concluir que a associa??o da laserterapia com a aplica??o t?pica de pr?polis acelera o processo e a qualidade do reparo no modelo animal de diabetes estudado.
Diabetes mellitus causes a number of systemic complications, including delay in the healing process. Several therapeutic alternatives have been tested in in vitro and in vivo studies in order to promote improvement in the process of wound repair in diabetic animals and individuals. The aim of the present study was to evaluate the effect of the association of low intensity laser therapy and topical administration of green propolis in cutaneous wounds model in rats with streptozotocin-induced diabetes. Ninety animals were allocated in the following groups: (N) normoglycemic (not induced), without therapy; (C) diabetic control, without therapy; (L) undergoing low intensity laser therapy (660 nm, 30 mW, 4 J/cm2); (P) submitted to topical administration of green propolis (30% alcoholic extract); and (LP) submitted to the combination of laser therapy and topical administration of green propolis. Therapeutic procedures were performed every 24 hours for 6 days. The surgical areas were photographed to evaluate the wound closure area. At intervals of 7, 14 and 21 days, the animals were submitted to euthanasia and subsequent removal of the wound area. The specimens were fixed, routinely processed, and embedded in paraffin and the slides obtained were stained by H/E and Picrosirius red for evaluation of re-epithelization, intensity of inflammatory infiltrate, and formation and organization of collagen, and also submitted to immunostaining for FGF-2 and VEGF. The quantitative data were submitted to non-parametric statistical tests, with a 95% confidence interval. The macroscopic evaluation of the wound area showed that the three groups submitted to treatment (L, P, and LP) showed an acceleration of wound retraction in relation to group C (p <0.001) from the 3rd to the 14th day, with results similar to group N. The LP group presented a better result in relation to the others (p <0.05) from the 5th day onwards. Histological analysis showed that the treated groups exhibited higher rates of re-epithelialization, especially in the L and LP groups, as well as lower inflammation rates, especially in the LP and P groups. Regarding the collagen I/III ratio, it was observed on the 7th day higher values in the LP group compared to the C group (p <0.05), similar to the N group. On the 14th day, the L group presented the highest proportion of the treated groups, resembling to the results of group N and with statistical difference for the other experimental groups (p <0.01). There was no difference in the collagen I/III ratio among the groups at the 21-day interval. The three treated groups (L, P, and LP) exhibited lower expression of FGF-2 and VEGF compared to N and C groups, especially the LP group (p <0.05). Taken together, the results of the present study allow us to conclude that the association of laser therapy with the topical application of propolis improves the cutaneous wound repair in the animal model of diabetes studied.
Penha, Raimundo Muniz. "O distrito industrial - DIRB - no contexto socio-ambiental da cidade de Rio Branco e do Estado do Acre." reponame:Repositório Institucional da UFSC, 1996. https://repositorio.ufsc.br/handle/123456789/111970.
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