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Dissertations / Theses on the topic 'Diagnostic agent'

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1

Rokka, Johan. "Agent-Based Argumentative Diagnostic Reasoning in Dementia." Thesis, Umeå universitet, Institutionen för datavetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-52092.

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This thesis describes the development of a source-based argumentation dialogue system in the medical domain of dementia. Its aim is to enable a physician and a computer agent to establish the presence or absence of a dementia condition or diagnoses for a specific patient. The participants take turn in making the moves in a dialogue, every move consists of an argument or a critical question (a challenge) and during the process of arguments and counterarguments an argumentation-tree, in which a winner may be declared, is constructed.The following four particular problems are formulated and solve
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Haigh, Julian Saunders. "Investigation in to the Effect of Spin Locking on Contrast Agent Relaxivity." PDXScholar, 2015. http://pdxscholar.library.pdx.edu/open_access_etds/2496.

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The current trend in magnetic resonance imaging (MRI) is towards higher external magnetic field strengths (B0) to take advantage of increased sensitivity and signal to noise ratio (SNR). Unfortunately, as (B0) increases the effectiveness (relaxivity) of clinical gadolinium (Gd3+)-based contrast agents (CAs) administered to enhance image contrast is significantly reduced. Excellent soft tissue contrast can be generated with current agents despite their non-optimum relaxivities but necessitates large doses. The limits of detection of a CA at high B0 fields can be lowered by recovering the lost r
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3

Kandanapitiye, Murthi S. "Synthesis of Biocompatible Nanoparticulate Coordination Polymers for Diagnostic and Therapeutic Applications." Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1429019837.

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4

Dumont, Julien. "Systèmes multi-agent pour le diagnostic pluri-disciplinaire." Phd thesis, Ecole Nationale Supérieure des Mines de Saint-Etienne, 2011. http://tel.archives-ouvertes.fr/tel-00844133.

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Ce travail de recherche est consacré à la formalisation et à la réalisation d'un processus de diagnostic pluridisplinaire. La particularité d'un tel diagnostic résulte du fait qu'il nécessite de nombreux spécialistes, chacun ayant des connaissances sur leur domaine. Le problème principal réside dans les interconnexions entre les domaines. Ces interconnexions peuvent ou non être connues et influer sur le diagnostic. Dans ce manuscrit, nous proposons de réaliser un diagnostic pluridisciplinaire l'aide d'un système multi-agents. Les agents élaborent un diagnostic local à un domaine puis, fusionne
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5

COSTA, ANDREW DINIZ DA. "A HYBRID DIAGNOSTIC-RECOMMENDATION APPROACH FOR MULTI-AGENT SYSTEMS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2008. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=13383@1.

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CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>Sistemas multi-agentes são sociedades com agentes autônomos e heterogêneos que podem trabalhar em conjunto para alcançar objetivos similares ou totalmente diferentes. Quando falhas acontecem enquanto algum agente de software tenta alcançar seus objetivos, torna-se importante entender porque tais falhas acontecem e o que pode ser feito para remediar tais problemas. Considerando o ambiente distribuído, dinâmico e a natureza dos sistemas multi-agentes, é importante definir os requisitos necessários para realizar diagnósticos
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6

Touaf, Samir. "Diagnostic logique des systèmes complexes dynamiques dans un contexte multi-agent." Université Joseph Fourier (Grenoble), 2005. http://www.theses.fr/2005GRE10038.

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Cette thèse propose une méthodologie pour la conception de systèmes de diagnostic fiables permettant d'appréhender les systèmes dynamiques complexes et spatialement distribués. Les résultats proposés s'appuient d'une part sur des techniques d'analyse diagnostic formelle ou à base de consistance, qui permettent de garantir la justesse de l'analyse diagnostic, et d'autre part, sur le paradigme multiagents. Les algorithmes proposés permettent de déduire tous les défauts possibles pour un comportement observé en les classant suivant différents critères de vraisemblance. Notre contribution a consis
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7

Hughes-Riley, Theodore. "Development and application of hyperpolarized krypton-83 as a new MRI contrast agent." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/14460/.

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Hyperpolarized (hp) gases such 129Xe and 83Kr (spin I = 1/2 and I = 9/2 respectively) can allow for significantly enhanced signal in a number of magnetic resonance applications. As a result there has been a growing interest in recent years to advance hp noble gas technology to non-invasively image the airspace of lungs, with the goal of developing a helpful probe for lung pathologies. 83Kr longitudinal relaxation (T1) has been shown to be sensitive to various surface properties, and may prove to be an interesting for identifying certain diseases including those that change surface chemistry (s
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8

Kumar, Akhauri Prakash. "Agent based diagnostic system for the defect analysis during chemical mechanical polishing (CMP)." Heimsheim Jost-Jetter, 2005. http://deposit.d-nb.de/cgi-bin/dokserv?idn=976561247.

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9

Bryson, Joshua Matthew. "The Design and Study of Lanthanide-Chelating Macromolecular Diagnostic and Delivery Agents." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/28726.

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Macromolecular magnetic resonance imaging (MRI) contrast agents have unique localization and contrast enhancement properties. We have designed and studied a monodisperse paramagnetic β-cyclodextrin click cluster (Gd10) decorated with Gd-containing arms and unique contrast enhancing polymers. To synthesize Gd10, a novel alkyne-functionalized diethylenetriaminetetraacetic acid chelate was created and coupled to a per-azido-β-cyclodextrin core and chelated with Gd(III) to yield the precursor macromolecule. Luminescence measurements were carried out using an analogous structure Eu(III)-containing
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10

Travagin, Fabio. "Synthesis of new contrast agents for biomedical applications." Doctoral thesis, Università del Piemonte Orientale, 2021. http://hdl.handle.net/11579/127849.

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Several different metal complexes are currently used in diagnostics and therapy (MRI, PET, SPECT, OI, TAT etc.). For their preparation a chelating agent (CA) is mandatory to hold the metal ion, to reduce its toxicity and to target its activity. Polyaminocarboxylates and polyaminophosphonates represent the best choice of CAs for the preparation of metal complexes exploited as imaging probes. These scaffolds ensure high thermodynamic and kinetic stability of the corresponding metal complex. However, their preparation is not always straightforward. During this PhD the research work was focused o
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Papachristou, Maria, George Kastis, Petros Stavrou, et al. "Radiolabeled methotrexate as a diagnostic agent of inflammatory target sites: A proof-of-concept study." SPANDIDOS PUBL LTD, 2017. http://hdl.handle.net/10150/626570.

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Methotrexate (MTX), as a pharmaceutical, is frequently used in tumor chemotherapy and is also a part of the established treatment of a number of autoimmune inflammatory disorders. Radiolabeled MTX has been studied as a tumor-diagnostic agent in a number of published studies. In the present study, the potential use of technetium-99m-labelled MTX (Tc-99m-MTX) as a radiotracer was investigated for the identification of inflammatory target sites. The labelling of MTX was carried out via a Tc-99m-gluconate precursor. Evaluation studies included in vitro stability, plasma protein binding assessment,
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12

Haverick, Mark Anthony. "Self-Assembling Peptide Amphiphile Contrast Agents as a Tumor Diagnostic Tool." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1316184031.

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13

Martina, Marie Sophie. "Conception de magnétoliposomes furtifs pour le diagnostic et la thérapie anti-cancéreuse." Paris 11, 2006. http://www.theses.fr/2006PA114831.

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Un nouveau système hybride résultant de l'encapsulation de nanoparticules d'oxyde de fer superparamagnétiques dans des vésicules phospholipidiques stabilisées stériquement par des chaînes de poly(éthylène glycol) (PEG) a été mis au point et caractérisé. Ces magnétoliposomes, stables et biocompatibles sont d'excellents agents de contraste pour l'imagerie par résonance magnétique (IRM) qui, par application d'un gradient de champ magnétique externe, peuvent être guidés in vivo dans le tissu tumoral ou un hémisphère cérébral. In vitro, la présence de chaînes de PEG réduit fortement l'association m
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YARABARLA, SRIRAMAKRISHNA. "Synthesis and Application of Polymer Stabilized, Water Dispersible Copper Based Nanoparticles as Anti-cancer and Diagnostic Agents." Kent State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=kent1492608832326.

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15

Nguyen, Thi Thanh Quynh. "Diagnostic distribué et commande tolérante aux défauts pour les systèmes multi-agents." Thesis, Reims, 2020. http://www.theses.fr/2020REIMS006.

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Un système multi-agents (MAS) peut-être défini par un groupe d'agents qui communiquent entre eux. Au cours de la dernière décennie, les MAS se sont révélés être une solution efficace et économique à de nombreux problèmes d'ingénierie complexes, difficiles voire impossibles à résoudre par un seul agent.Malgré l’abondance de résultats dans la littérature concernant sur le contrôle coopératif des MAS, il y a encore des points d’amélioration, en particulier en termes de fiabilité et de performance de fonctionnement du contrôle coopératif en cas de panne. Cette thèse vise une contribuer à la résolu
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16

Radkowitsch, Anika [Verfasser], and Frank [Akademischer Betreuer] Fischer. "Facilitating collaborative diagnostic reasoning : effects of collaboration scripts in agent-based medical simulations / Anika Radkowitsch ; Betreuer: Frank Fischer." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/1234912015/34.

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17

Webber, Benjamin Charles. "Investigation of the Structure and Dynamics of Regioisomeric Eu³⁺ and Gd³⁺ Chelates of NB-DOTMA: Implications for MRI Contrast Agent Design." PDXScholar, 2013. https://pdxscholar.library.pdx.edu/open_access_etds/1498.

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The detection of disease and abnormal pathology by magnetic resonance imaging (MRI) has been aided significantly by the use of gadolinium (Gd3+)-based contrast agents (CAs) over the past three decades. MRI and MRI CAs play a critical role in diagnosing tumors and diseases of the central nervous system. The agents used clinically have been shown to safely increase MRI contrast despite the toxicity of Gd3+, owing to the high kinetic and thermodynamic stability of these chelates. However, current CAs enhance contrast at a small fraction of what is theoretically possible. This leads to the necessi
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18

Bosco, Lionel. "Développement de sondes radicalaires intelligentes pour le diagnostic par IRM réhaussée par l'effet Overhauser." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4756/document.

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Ce travail expose deux stratégies pour le développement de nouveaux agents de contraste pour le diagnostic par IRM rehaussée par l’effet Overhauser.Le premier thème de ce travail est consacré au développement d’une sonde radicalaire, de type nitroxyde, capable de modifier sa signature RPE (Résonance Paramagnétique Electronique) en fonction d’une activité enzymatique. Cette modification, due à un changement conformationnel, a permis une irradiation microonde sélective de la sonde libérée par protéolyse. Cette particularité a pu être appliquée à l’IRM rehaussée par l’effet Overhauser et une amél
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19

SANCHEZ, VERONIQUE. "Synthese, emulsification et evaluation in vivo de composes fluores radioopaques pour leur emploi comme agent de contraste en diagnostic medical." Nice, 1993. http://www.theses.fr/1993NICE4670.

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Les developpements des fluorocarbures en diagnostic ont etabli leur interet comme agent de contraste lorsqu'ils sont rendus radioopaques par la presence d'atome lourd, tel le brome dans le bromure de perfluorooctyle (pfob). Cependant, l'effet de contraste du a ce seul atome de brome est modere, compare a celui de l'iode des opacifiants radiologiques actuels. Une etude realisee sur divers fluorocarbures ethyleniques iodes, dibromes et tribromes a permis de selectionner les 1,2-bis(f-alkyl)iodoethenes, r#f#ci=chr#f(fnnie), et les 1-alkyl-2-(f-alkyl)iodoethenes, r#fch=cir#h(fnhmie), comme agents
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20

Perng, John Kangchun. "Ultrasound imaging of oxidative stress in vivo with chemically generated gas microbubbles." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/43608.

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Ultrasound contrast agents (UCA) have tremendous potential for in vivo molecular imaging because of their high sensitivity and great spatial resolution of ultrasound imaging. However, the diagnostic potential of UCAs has been difficult to exploit because current contrast agents are based on pre-formed microbubbles, which can only detect cell surface receptors. In this work, we demonstrated that chemical reactions that generate gas forming molecules can be used to perform molecular imaging by ultrasound in vivo. This new approach for generating ultrasound contrast agents was demonstrated by
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21

Kumar, Akhauri Prakash [Verfasser]. "Agent based diagnostic system for the defect analysis during chemical mechanical polishing (CMP) / Universität Stuttgart, IFF, Institut für Industrielle Fertigung und Fabrikbetrieb ... Akhauri Prakash Kumar." Heimsheim : Jost-Jetter, 2005. http://d-nb.info/976561247/34.

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22

Hingot, Vincent. "Development of ultrasound localization microscopy to measure cerebral perfusion during stroke : a study in mouse models prior to its translation in humans." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS562.

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L’échographie est une technique d’imagerie médicale employant des ultrasons. Un examen classique se base sur deux modes principaux, le mode B pour l’imagerie anatomique et le mode Doppler pour l’imagerie des flux sanguins.Dans le contexte des maladies cérébro-vasculaires, l’échographie sert principalement à estimer les altérations du flux sanguin dans les artères cérébrales majeures au travers du Doppler transcranien. Cependant, la faible qualité des images à travers le crâne ne permet pas à l’échographie d’être aussi performante que l’imagerie par résonance magnétique.Les récents progrès en é
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23

Douaiher, Marie-Noëlle. "Pathogénicité de Mycosphaerella graminicola, agent de la septoriose du blé : rôle des enzymes de dégradation des parois cellulaires." Littoral, 2006. http://www.theses.fr/2006DUNK0136.

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Afin d'étudier la production des activités enzymatiques de dégradation des parois cellulaires de blé in vitro par Mycosphaerella graminicola, deux souches de référence (323 et 94269) ont été cultivées sur le milieu synthétique S dans lequel le galactose et/ou les parois cellulaires constituent les sources de carbone. Les cinétiques de production ont montré des niveaux d'activités différents entre les deux souches et selon les sources de carbone utilisées. Cinq des sept activités recherchées ont été produites en quantités significatives : xylanase, β-xylosidase, polygalacturonase, cellulase et
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Tarrieu, Frédérique. "Analyse de la diversité phylogénétique de "Trypanosoma cruzi cruzi", agent de la maladie de Chagas, par séquençage des gènes 18S et Tc52. Applications au diagnostic moléculaire." Montpellier 2, 2000. http://www.theses.fr/2000MON20220.

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La diversite genetique de trypanosoma cruzi cruzi, un protozoaire parasite responsable de la maladie de chagas en amerique latine, est considerable. Les populations naturelles de ce parasite presentent une structure clonale caracterisee par la propagation de lignees uniparentales stables sur de grandes aires geographiques et dans le temps. Les analyses menees sur la bases de marqueurs multilocus (isoenzymes et rapd) ont mis en evidence l'existence de deux lignees majeures, les dtus (discrete typing units) 1 et 2. La dtu 2 est subdivisee en cinq dtus 2a a 2e. Dans notre etude, nous avons analys
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Benchetrit, Michael. "Identification de levures en milieu hospitalier : comparaison de 4 galeries à lecture colorimétrique." Paris 5, 1997. http://www.theses.fr/1997PA05P041.

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Lucain, Pierrre-Eric. "IRM-ferumoxides versus portoscanner dans la détection des métastases hépatiques." Montpellier 1, 1996. http://www.theses.fr/1996MON11016.

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27

Dupas, Benoît. "Detection des metastases hepatiques et caracterisation de la necrose cellulaire aigue en irm : action des agents de contraste ; nanoparticules d'oxyde de fer, dysprosium et gadolinium." Angers, 1996. http://www.theses.fr/1996ANGE0505.

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28

Platteau, Jean-Marc. "L'agent de maitrise face à l'informatique. Enquête-diagnostic a Renault-Flins. : L'évaluation sociologique : une exigence majeure pour l'entreprise en quête de competitivite." Lille 1, 1988. http://www.theses.fr/1988LIL12011.

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L'informatique, un facteur d'efficacité pour les organisations? Assurément. . . . Mais encore faut-il qu'elle ne subisse pas de la part des utilisateurs les affres de "l'effet placard", car tel est bien le risque majeur qui guette ses promoteurs lorsqu'ils ne s'interrogent pas suffisamment sur les conditions propres à favoriser une insertion sociale réussie. La démarche choisie valorise-t-elle une dynamique de l'autonomie et de l'apprentissage? Alors, il devient possible de donner au projet initial les dimensions d'un véritable projet sociotechnique. S'appuie-t-elle sur une exploration approfo
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29

Zurkiya, Omar. "Magnetic Resonance Molecular Imaging Using Iron Oxide Nanoparticles." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/19848.

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Magnetic resonance imaging (MRI) is regularly used to obtain anatomical images, greatly advancing biomedical research and clinical health care today, but its full potential in providing functional, physiological, and molecular information is only beginning to emerge. The goal of magnetic resonance molecular imaging is to utilize MRI to acquire information on the molecular level. This dissertation is focused on ways to increase the use of MRI for molecular imaging using superparamagnetic iron oxide (SPIO) nanoparticle induced MRI contrast. This work is divided into three main sections: <B>1)<I>
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30

Dey, Priyanka. "Hybrid polymer/metal nanoparticles with surface enhanced raman tracking for potential use in nanomedicine." Thesis, Queensland University of Technology, 2014. https://eprints.qut.edu.au/74991/1/Priyanka_Dey_Thesis.pdf.

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This project was a preliminary step towards the development of novel methods for early stage cancer diagnosis and treatment. Diagnostic imaging agents with high Raman signal enhancement were developed based on tailored assemblies of gold nanoparticles, which demonstrated potential for non-invasive detection from deep under the skin surface. Specifically designed polymers were employed to assemble gold nanoparticles into controlled morphologies including dimers, nanochains, nanoplates, globular and core-satellite nanostructures. Our findings suggest that the Raman enhancement is strongly depend
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31

Bernhard, Claire. "Synthèse d'agents chélatants bifonctionnels macrocycliques pour le marquage de molécules biologiques par des métaux : application en imagerie médicale." Thesis, Dijon, 2011. http://www.theses.fr/2011DIJOS024/document.

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L’imagerie moléculaire est devenue incontournable pour le diagnostic et le traitement de cancers. Cette discipline regroupe un ensemble de techniques telles que la tomodensitométrie (CT), l’Imagerie par Résonance Magnétique (IRM), l’imagerie optique ou encore l’imagerie nucléaire (tomographie par émission de positons TEP, tomographie d’émission monophotonique TEMP). Chacune de ces techniques possède ses propres avantages et inconvénients et ne peut apporter à elle seule des informations anatomiques et fonctionnelles suffisantes. Les travaux actuels sont portés sur la conception de systèmes dit
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32

Shah, N. H. "Exception diagnosis in open multi-agent systems." Thesis, Coventry University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425240.

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Md, Tohid Siti Farah. "Synthesis of potential cancer therapeutic and diagnostic agents." Thesis, Cardiff University, 2011. http://orca.cf.ac.uk/54438/.

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The need to find novel anticancer agents with better potency, efficacy and safety are highly demanded. Therefore, the first part of the study was aimed to synthesise new compounds based on stilbenes, indole-based isoxazoles and tricyclic anilides as potential antitumour agents, which later will be evaluated for their anticancer properties. The syntheses of substituted stilbenes were achieved via catalyzed or uncatalyzed methods, yielding stilbene analogues in moderate to good yields. Preliminary antiproliferative studies on four cancer cell lines (prostate, non-small lung, colon and breast) de
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Simmons, Suzanne Clare. "Development of Aptamers as Diagnostic and Therapeutic Agents." Thesis, Open University, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.524784.

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Ren, Xiaoxu. "An agent-based system for distributed fault diagnosis." Thesis, University of Sheffield, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401197.

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Grimaldo, Morón José Teófilo. "Contribution à la synthèse de macrocycles tétraphosphorés : ligands polydentates présentant un intérêt biomédical." Grenoble 1, 1987. http://www.theses.fr/1987GRE10161.

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Synthese de ligands macrocycles tetraphores, complexants potentiels de cations paramagnetiques (gd**(3+), fe**(3+)) et de nucleide radioactifs. Etude de la reactivite de ces ligands et des essais de complexation
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Nguyen, Vo Thu An. "Magnetic polyion complex micelles as therapy and diagnostic agents." Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0138/document.

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Ce manuscrit de thèse présente la synthèse de nanoparticules d’oxyde de fer superparamagnétiques couramment appelées SPIONs servant d’agents de contraste pour l’imagerie par résonance magnétique (IRM) et la génération de chaleur pour la thérapie cellulaire par hyperthermie induite par champ magnétique radiofréquence (HMRF). Le contrôle des tailles et de la distribution en tailles des SPIONs et donc de leurs propriétés magnétiques a été obtenu en utilisant un copolymère arborescent G1 (substrat de polystyrène branché en peigne noté G0, greffé avec des groupements pendants poly(2-vinyle pyridine
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Matthews, Susan Elizabeth. "Synthesis of biodegradable polymers for delivery of diagnostic agents." Thesis, University of Bath, 1995. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296299.

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Kairdolf, Brad A. "Development of polymer-coated nanoparticle imaging agents for diagnostic applications." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/31845.

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Thesis (Ph.D)--Biomedical Engineering, Georgia Institute of Technology, 2010.<br>Committee Chair: Nie, Shuming; Committee Member: Bao, Gang; Committee Member: Murthy, Niren; Committee Member: Varma, Vijay; Committee Member: Wang, Zhong Lin. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Serafini, Stefano. "Quality control agent: self-adaptive laser vibrometry for on line diagnostics." Doctoral thesis, Università Politecnica delle Marche, 2013. http://hdl.handle.net/11566/242695.

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In questa tesi verrà descritto come sia possibile aumentare la performance di sistemi di misura basati sulla vibrometria laser, realizzando dei comportamenti auto-adattativi con lo scopo di ridurre l’incertezza di misura. I test sulle vibrazioni sono delle procedure ben note e largamente utilizzate per verificare la conformità a specifiche di qualità dei prodotti che contengono parti in movimento. Questi test posti alla fine di una linea di produzione forniscono delle informazioni utili per descrivere la qualità di un prodotto prima del suo stoccaggio e vendita. Nell’industria moderna l
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Chin, Chien Ting. "Modelling the behaviour of microbubble contrast agents for diagnostic ultrasound." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ59006.pdf.

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42

Cheung, Shing-chung, and 張成忠. "Novel contrast agents for magnetic resonance imaging." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42841550.

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43

Cheung, Shing-chung. "Novel contrast agents for magnetic resonance imaging." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42841550.

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44

Goumas, Dimitrios. "Possibilites de detection d'erwinia chrysanthemi pv. Dianthicola (hellmers) dickey 1979-agent de la bacteriose du dahlia sp. Evaluation des methodes immunoenzymatiques pour le controle sanitaire du materiel de propagation." Paris 6, 1987. http://www.theses.fr/1987PA066405.

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La bacteriose a e. Chrysanthemi pv. Dianthicola (echr) facteur limitant de la production du dahlia est transmise par la multiplication vegetative. Afin de proposer une methode de diagnostic plus precise que la detection visuelle, les methodes immunoenzymatiques ont ete etudiees et adaptees pour la detection d'echr dans les tissus du dahlia. La methode das-elisa (double antibody sandwich) est evaluee par rapport aux methodes de diagnostic de reference (isolement et immunofluorescence). Son utilisation, pour l'analyse sanitaire du materiel de propagation vis-a-vis d'echr seul et associe eventuel
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Marques, Gonçalo Nogueira. "Clinical approach to respiratory mucormycosis in a bottlenose dolphin (Tursiops truncatus) calf under human care." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2019. http://hdl.handle.net/10400.5/19336.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Several fungi are described to cause invasive infections in dolphins, the respiratory system being a common site of involvement. Mucormycosis is considered one of the most devastating fungal infections in dolphins, associated with an elevated mortality rate, where hyphae are capable of invading blood vessels, producing tissue infarction and necrosis. A one-year-old male bottlenose dolphin (Tursiops truncatus) calf presented with a history of recurrent episodes of leukocytosis and occasional respiratory signs. During a routine faecal
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Stöckmann, Henning. "The development of new agents for molecular imaging in cancer." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610030.

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Barlas, Irtaza. "A Multiagent Framework for a Diagnostic and Prognostic System." Diss., Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/5290.

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A Multiagent Framework for a Diagnostic and Prognostic System Irtaza Barlas 124 Pages Directed By: Dr. George Vactsevanos The shortcomings of the current diagnostic and prognostic systems stem from the limitations of their frameworks. The framework is typically designed on the passive, open loop, static, and isolated notions of diagnostics, in that the framework does not observe its diagnostic results (open-looped), hence can not improve its performance (static). Its passivity is attributed to the fact that an external event triggers the diagnostic or prognostic action. There is also no e
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Moreau, Mathieu. "Marquage de molécules biologiques par des complexes de radiométaux à base de polyamines macrocycliques." Phd thesis, Université de Bourgogne, 2012. http://tel.archives-ouvertes.fr/tel-00796881.

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Ce travail de thèse réalisé à l'Institut de Chimie Moléculaire de l'Université de Bourgogne porte dans un premier temps sur la synthèse d'agents chélatants bifonctionnels adaptés à la chélation de radiométaux trivalents, notamment l'indium-111. La plus grande partie de ce travail a ensuite consisté à réaliser le greffage d'un agent chélatant bifonctionnel dérivé du DOTA sur différents anticorps ou fragments d'anticorps monoclonaux : le trastuzumab (anti HER2, traitement de cancers du sein), le cétuximab (anti EGFR, traitement de nombreux cancers, dont le cancer colorectal) et l'abciximab (anti
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Pires, Layla. "Optical strategies for diagnosis and treatment of melanoma." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-01122017-154608/.

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Melanoma is a pigmented tumor that originates from the melanocytes; pigmented cells present throughout the body, including skin and iris. The cutaneous form is the most common type, and it represents about 5% of the skin tumors diagnosed in Brazil. Although it does not have a high incidence, it represents about 80% to 85% of all skin tumor deaths. The second most frequent type of melanoma is ocular. It represents 5% of all melanoma cases and is a potentially lethal disease, especially when it causes metastasis. The main therapeutic approach for melanomas, in general, is surgery, with resection
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Davoodi, Samirmi Farhad. "Multi-agent and knowledge-based system for power transformer fault diagnosis." Thesis, University of Liverpool, 2013. http://livrepository.liverpool.ac.uk/14455/.

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Transformer reliability and stability are the key concerns. In order to increase their efficiency, an automatic monitoring and fault diagnosing of the power transformers are required. Dissolved Gas Analysis (DGA) is one of the most important tools to diagnose the condition of oil-immersed transformer. Agents technology as a new, robust and helpful technique, successfully applied for various applications. Integration of the Multi-Agent System (MAS) with knowledge base provides a robust system for various applications, such as fault diagnosis and automated actions performing, etc. For this purpo
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