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Journal articles on the topic "Diagnosis related groups Victoria"

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Dowling, Pat. "The Discharge Brokerage Program." Australian Journal of Primary Health 2, no. 1 (1996): 134. http://dx.doi.org/10.1071/py96019.

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In response to government policies on case mix funding and Diagnosis Related Groups (DRGs), Caulfield Community Care Centre, in consultation with the Inner South Community Health Service in Victoria, made a submission for government funding to run an early discharge program. It was called a Discharge Brokerage Program rather than an early discharge program, because of not wanting patients to be anxious about leaving hospital early.
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Peck, Blake, Daniel Terry, and Kate Kloot. "The Socioeconomic Characteristics of Childhood Injuries in Regional Victoria, Australia: What the Missing Data Tells Us." International Journal of Environmental Research and Public Health 18, no. 13 (June 30, 2021): 7005. http://dx.doi.org/10.3390/ijerph18137005.

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Background: Injury is the leading cause of death among those between 1–16 years of age in Australia. Studies have found that injury rates increase with socioeconomic disadvantage. Rural Urgent Care Centres (UCC) represent a key point of entry into the Victorian healthcare system for people living in smaller rural communities, often categorised as lower socio-economic groups. Emergency presentation data from UCCs is not routinely collated in government datasets. This study seeks to compare socioeconomic characteristics of children aged 0–14 attending a UCC to those who attend a 24-h Emergency Departments with an injury-related emergency presentation. This will inform gaps in our current understanding of the links between socioeconomic status and childhood injury in regional Victoria. Methods: A network of rural hospitals in South West Victoria, Australia provide ongoing detailed de-identified emergency presentation data as part of the Rural Acute Hospital Data Register (RAHDaR). Data from nine of these facilities was extracted and analysed for children (aged 0–14 years) with any principal injury-related diagnosis presenting between 1 February 2017 and 31 January 2020. Results: There were 10,137 injury-related emergency presentations of children aged between 0–14 years to a participating hospital. The relationship between socioeconomic status and injury was confirmed, with overall higher rates of child injury presentations from those residing in areas of Disadvantage. A large proportion (74.3%) of the children attending rural UCCs were also Disadvantaged. Contrary to previous research, the rate of injury amongst children from urban areas was significantly higher than their more rural counterparts. Conclusions: Findings support the notion that injury in Victoria differs according to socioeconomic status and suggest that targeted interventions for the reduction of injury should consider socioeconomic as well as geographical differences in the design of their programs.
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Fehlberg, Trafford, John Rose, Glenn Douglas Guest, and David Watters. "The surgical burden of disease and perioperative mortality in patients admitted to hospitals in Victoria, Australia: a population-level observational study." BMJ Open 9, no. 5 (May 17, 2019): e028671. http://dx.doi.org/10.1136/bmjopen-2018-028671.

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ObjectivesComprehensive reporting of surgical disease burden and outcomes are vital components of resilient health systems but remain under-reported. The primary objective was to identify the Victorian surgical burden of disease necessitating treatment in a hospital or day centre, including a thorough epidemiology of surgical procedures and their respective perioperative mortality rates (POMR).DesignRetrospective population-level observational study.SettingThe study was conducted in Victoria, Australia. Access to data from the Victorian Admitted Episodes Dataset was obtained using the Dr Foster Quality Investigator tool. The study included public and private facilities, including day-case facilities.ParticipantsFrom January 2014 to December 2016, all admissions with an International Statistical Classification of Diseases-10 code matched to the Global Health Estimates (GHE) disease categories were included.Primary and secondary outcome measuresAdmissions were assigned a primary disease category according to the 23 GHE disease categories. Surgical procedures during hospitalisations were identified using the Australian Refined Diagnosis Related Groups (AR-DRG). POMR were calculated for GHE disease categories and AR-DRG procedures.ResultsA total of 4 865 226 admitted episodes were identified over the 3-year period. 1 715 862 (35.3%) of these required a surgical procedure. The mortality rate for those undergoing a procedure was 0.42%, and 1.47% for those without. The top five procedures performed per GHE category were lens procedures (162 835 cases, POMR 0.001%), caesarean delivery (76 032 cases, POMR 0.01%), abortion with operating room procedure (65 451 cases, POMR 0%), hernia procedures (52 499 cases, POMR 0.05%) and other knee procedures (47 181 cases, POMR 0.004%).ConclusionsConditions requiring surgery were responsible for 35.3% of the hospital admitted disease burden in Victoria, a rate higher than previously published from Sweden, New Zealand and the USA. POMR is comparable to other studies reporting individual procedures and conditions, but has been reported comprehensively across all GHE disease categories for the first time.
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Iansek, Robert, and Mary Danoudis. "Patients’ Perspective of Comprehensive Parkinson Care in Rural Victoria." Parkinson's Disease 2020 (March 31, 2020): 1–7. http://dx.doi.org/10.1155/2020/2679501.

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Introduction. There is a higher prevalence of Parkinson’s disease (PD) in rural Australia and a poorer perceived quality of life of rural Australians with PD. Coordinated multidisciplinary teams specialised and experienced in the treatment of PD are recommended as the preferred model of care best able to manage the complexities of this disorder. There remains a lack of team-based specialised PD services in rural Australia available to people living with PD. This study aims to explore how the lack of specialised PD services impacts on the person’s experiences of the health care they receive in rural Victoria. This study compared the health-care experiences of two different cohorts of people with PD living in rural Victoria; one cohort living in East Gippsland have had an established comprehensive care model implemented with local trained teams and supported by a metropolitan PD centre, and the other cohort was recruited from the remainder of Victoria who had received standard rural care. Methods. This descriptive study used a survey to explore health-care experiences. Questionnaires were mailed to participants living in rural Victoria. Eligibility criteria included having a diagnosis of PD or Parkinsonism and sufficient English to respond to the survey. The validated Patient-Centred Questionnaire for PD was used to measure health-care experiences. The questions are grouped accordingly under one of the 6 subscales or domains. Outcomes from the questionnaire included summary experience scores (SES) for 6 subscales; overall patient-centeredness score (OPS); and quality improvement scores (QIS). Secondary outcomes included health-related quality of life using the disease-specific questionnaire PDQ39; disease severity using the Hoehn and Yahr staging tool; and disability using the Movement Disorders Society-Unified Parkinson’s Disease Rating Scale, part II. Results. Thirty-nine surveys were returned from the East Gippsland group and 68 from the rural group. The East Gippsland group rated significantly more positive the subscales “empathy and PD expertise,” P=0.02, and “continuity and collaboration of professionals,” P=0.01. The groups did not differ significantly for the remaining 4 subscales (P>0.05) nor for the OPS (P=0.17). The QIS showed both groups prioritised the health-care aspect “provision of tailored information” for improvement. Quality of life was greater (P<0.05) and impairment (P=0.012) and disability were less (P=0.002) in the East Gippsland group. Conclusion. Participants who received health care from the East Gippsland program had better key health-care experiences along with better QOL and less impairment and disability. Participants prioritised provision of information as needing further improvement.
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Cossette, Adam P., Amanda J. Adams, Stephanie K. Drumheller, Jennifer H. Nestler, Brenda R. Benefit, Monte L. McCrossin, Frederick K. Manthi, Rose Nyaboke Juma, and Christopher A. Brochu. "A new crocodylid from the middle Miocene of Kenya and the timing of crocodylian faunal change in the late Cenozoic of Africa." Journal of Paleontology 94, no. 6 (September 8, 2020): 1165–79. http://dx.doi.org/10.1017/jpa.2020.60.

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AbstractBrochuchus is a small crocodylid originally based on specimens from the early Miocene of Rusinga Island, Lake Victoria, Kenya. Here, we report occurrences of Brochuchus from several early and middle Miocene sites. Some are from the Lake Victoria region, and others are in the Lake Turkana Basin. Specimens from the middle Miocene Maboko locality form the basis of a new species, Brochuchus parvidens, which has comparatively smaller maxillary alveoli. Because of the smaller alveoli, the teeth appear to be more widely spaced in the new species. We also provide a revised diagnosis for Brochuchus and its type species, B. pigotti. A phylogenetic analysis supports a close relationship between Brochuchus and tube-snouted Euthecodon, but although relationships among crocodylids appear poorly resolved in the set of optimal trees, this is because Brochuchus and Euthecodon, along with early Miocene “Crocodylus” gariepensis from the early Miocene of Namibia, jointly adopt two distinct positions—either closely related to the living sharp-nosed crocodile (Mecistops) or to a group including the living dwarf crocodiles (Osteolaemus). Character support for a close relationship with Mecistops is problematic, and we suspect a closer relationship to Osteolaemus will be recovered with improved sampling, but the results here are ambiguous. In either case, Brochuchus is more closely related to living groups not currently found in East Africa. This material helps constrain the timing of crocodylian faunal turnover in the East African Rift Valley System, with endemic lineages largely being replaced by Crocodylus in the middle or late Miocene possibly in response to regional xerification and the replacement of continuous rainforest cover with open grasslands and savannas.UUID: http://zoobank.org/e6f0b219-5f3e-44e5-bdb9-60a4fae8d126
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Clapperton, Angela, Stuart Newstead, Lyndal Bugeja, and Jane Pirkis. "Differences in Characteristics and Exposure to Stressors Between Persons With and Without Diagnosed Mental Illness Who Died by Suicide in Victoria, Australia." Crisis 40, no. 4 (July 2019): 231–39. http://dx.doi.org/10.1027/0227-5910/a000553.

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Abstract. Background: Mental illness is an established risk factor for suicide. To develop effective prevention interventions and strategies, the demographic characteristics and stressors (other than, or in addition to, mental illness) that can influence a person's decision to die by suicide need to be identified. Aim: To examine cases of suicide by the presence or absence of a diagnosed mental illness (mental illness status) to identify differences in factors associated with suicide in the groups. Method: Logistic regression analyses were used to investigate mental illness status and exposure to stressors among 2,839 persons who died by suicide in Victoria, Australia (2009–2013), using the Victorian Suicide Register. Results: Females, metropolitan residents, persons treated for physical illness/injury, those exposed to stressors related to isolation, family, work, education, and substance use and those who had made a previous suicide attempt had increased odds of having a diagnosed mental illness. Employed persons had decreased odds of having a diagnosed mental illness. Limitations: The retrospectivity of data collection as well as the validity and reliability of some of the data may be questionable owing to the potential for recall bias. Conclusion: The point of intervention for suicide prevention cannot always be a mental health professional; some people who die by suicide either do not have a mental illness or have not sought help.
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SHARIF, NAVEED, NAZIR AHMED, FAWAD HAMEED, Nosheen Rehan, and Jawad Khan. "PULMONARY TUBERCULOSIS." Professional Medical Journal 18, no. 01 (March 10, 2011): 89–92. http://dx.doi.org/10.29309/tpmj/2011.18.01.1865.

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Objective: To study the age related radiological finding in pulmonary tuberculosis. Study design: A cross sectional study. Place and duration of study: From January 2009 to December 2009 pulmonary department of Bahawal Victoria Hospital Bahawal Pur. Patients and method: The cases diagnosed as pulmonary tuberculosis of either gender above age of 12 years were included in the study. Patients suffering from extra pulmonary tuberculosis, treatment failure, relapse, drug resistant tuberculosis and HIV sero-positive patients were excluded from the study. Patients were divided into groups according to the age. Group 1 consist of patients having age ≥ 50years while group 2 consist of patients having <50 years. Data was recorded on the Proforma and was analyzed statistically on SPSS 11. Results: this study consists of 106 patients and divided into two groups. It has been found that apical zone of lung involvement was more common in patients younger than 50 years while involvement of lower zone was more common in patients with age ≥50years. No significant difference was found regarding the involvement of middle zone, multiple zones and the type of lesions as the p-value was >0.05. Conclusions: the elderly patients with pulmonary tuberculosis have predominant involvement of lower zones. So, lower zone involvement of radiological lesions should be evaluated for pulmonary tuberculosis to start the treatment earlier and to minimize the risk of missing the diagnosis.
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Otome, Ohide, Alexander Wright, Vanika Gunjaca, Steve Bowe, and Eugene Athan. "The Economic Burden of Infective Endocarditis due to Injection Drug Use in Australia: A Single Centre Study—University Hospital Geelong, Barwon Health, Victoria." Interdisciplinary Perspectives on Infectious Diseases 2022 (December 16, 2022): 1–5. http://dx.doi.org/10.1155/2022/6484960.

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Background. Injection drug use (IDU) is a well-recognized risk factor for infective endocarditis (IE). Associated complications from IDU result in significant morbidity and mortality with substantial cost implications. The aim of this study was to determine the cost burden associated with the management of IE due to IDU (IE-IDU). Methods. We used data collected prospectively on patients with a diagnosis of IE-IDU as part of the international collaboration on endocarditis (ICE). The cost of medical treatment was estimated based on diagnosis-related groups (DRG) and weighted inlier equivalent separation (WIES). Results. There were 23 episodes from 21 patients in 12 years (2002 to 2014). The costing was done for 22 episodes due to data missing on 1 patient. The median age was 39 years. The gender distribution was equal. Heroin (71%) and methamphetamine (33%) were the most frequently used. 74% (17/23) required intensive care unit (ICU) admission. The median ICU length of stay (LOS) was 4 days (IQR (Interquartile range); 2 to 40 days) whilst median total hospital LOS was 40 days (IQR; 1 to 119 days). Twelve patients (52%) underwent valve replacement surgery. Mortality was 13% (3/23). The total medical cost for the 22 episodes is estimated at $1,628,359 Australian dollars (AUD). The median cost per episode was a median cost of $ 61363 AUD (IQR: $2806 to $266,357 AUD). We did not account for lost productivity and collateral costs attributed to concurrent morbidity. Conclusion. Within the limitations of this small retrospective study, we report that the management of infective endocarditis caused by injection drug use can be associated with significant financial cost.
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Gibbs, Cedric C. J. "Diagnosis related groups." Medical Journal of Australia 143, no. 6 (September 1985): 227. http://dx.doi.org/10.5694/j.1326-5377.1985.tb122949.x.

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Tonkin, David. "Diagnosis related groups." Medical Journal of Australia 143, no. 6 (September 1985): 261. http://dx.doi.org/10.5694/j.1326-5377.1985.tb122972.x.

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Dissertations / Theses on the topic "Diagnosis related groups Victoria"

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Piterman, Hannah, and Hannah Piterman@med monash edu au. "Tensions around introducing co-ordinated care a case study of co-ordinated care trial." Swinburne University of Technology, 2000. http://adt.lib.swin.edu.au./public/adt-VSWT20050418.092951.

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The aim of the research was to analyse the organisational dynamics surrounding a health care reform implementation process associated with the introduction of coordinated care, which is an Australian Government initiative to introduce structural changes to the funding and delivery of health-care in response to rising health care costs. A longitudinal case study of an implementation team was studied. This included the perceptions and experiences of individuals and institutions within hospitals, the general practice community and Divisions of General Practice. Furthermore, the case study explored organisational structures, decision-making processes and management systems of the Project and included an examination of the difficulties and conflicts that ensued. The broader context of health care reform was also considered. The study found that an effective change management strategy requires clarity around the definition of primary task in health care delivery, particularly when the task is complex and the environment uncertain. This requires a management and support structure able to accommodate the tensions that exists between providing care and managing cost, in a changing and complex system. The case study indicated that where tensions were not managed the functions of providing care and managing costs became disconnected, undermining the integrity of the task and impacting on the effective facilitation of the change process and hence, the capacity of stakeholders to embrace the model of co-ordinated care. Moreover, the micro dynamics of the project team seemed to parallel the macro dynamics of the broader system where economic and health care provision imperatives clash. Through its close analysis of change dynamics, the study provides suggestions for the improved engagement of stakeholders in health care change.
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Ullmann, Sven-Roland. "Auswirkungen differierender Fallgewichtungen innerhalb von Diagnosis Related Groups." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969843658.

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Kortevoß, Axel. "Krankenhausplanung unter Bedingungen der German-Diagnosis Related Groups." Diss., lmu, 2005. http://nbn-resolving.de/urn:nbn:de:bvb:19-48261.

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Schum, Alexandra. "Erlösvergleich für Schockraumpatienten nach Bundespflegeverordnung, Australian Refined- Diagnosis Related Groups (AR-DRG) und German Diagnosis-Related Groups (G-DRG) einer Klinik der Maximalversorgung." Diss., lmu, 2006. http://nbn-resolving.de/urn:nbn:de:bvb:19-63169.

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Noronha, Marina Ferreira de. "Classificacao de hospitalizacoes em Ribeirao Preto: os diagnosis related groups." Sao Paulo : [s.n.], 2001. http://www.saudepublica.bvs.br/P/teses/MHdout3.pdf.

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Nickel, Marc. "Kalkulation von Fallkosten für Diagnosis Related Groups (DRGs) in der Kardiologie." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=970094248.

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Rutz, Stefan. "Die Einführung von Diagnosis Related Groups in Deutschland : Interessen - Anreize - erste Ergebnisse /." Lohmar : Eul, 2006. http://deposit.d-nb.de/cgi-bin/dokserv?id=2887385&prov=M&dok_var=1&dok_ext=htm.

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Gao, Fei, and 高菲. "Systematic review of the impacts of diagnosis related groups and the challenges of the implementation in Mainland China." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/206937.

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1.1 Background: Since Diagnosis Related Groups (DRGs) systems were firstly introduced in USA in 1983, they have begun to be implemented in more developed countries and some developing countries among the world during two decades. As one of the prospective payment systems, it focuses on enhancing the efficiency through reduction in the length of stays in hospitals, and improves the health care services by decreasing and controlling the unnecessary treatments. This paper reviewed the impacts of DRGs both in the countries with long period’s implementation and in China, including the above beneficial outcomes and negative influences in health care delivery. Furthermore, considering the current concerns of health care delivery in Mainland China, this paper discussed the difficulties and challenges in widely implementation over the whole country. 1.2 Methods: This study focused on the published papers in English through Pubmed, Google scholar, Google and in Chinese through CNKI. The articles in Chinese were searched from 1994. A literature search of all articles was conducted using keywords such as DRGs, impacts, efficiency, and quality both in English and in Chinese, so that relevant studies had been chosen according to the aims of the review. 1.3 Result: This review revealed the beneficial outcomes within health care delivery after the implementation of DRGs, which focused on the decrease in average length of hospital stay and the medical expenses per case. In addition, the relevant adverse outcomes had been reflected simultaneously through the studies, which were mainly indicated through the increase in emergency visits and mortality rates. The findings included both the benefits DRGs brings and negative outcomes, and the current effects of DRGs in Mainland China. 1.4 Conclusion: Diagnosis Related Groups (DRGs) system plays the different roles in different kinds of health care systems. It controls the medical expenses through less hospital activities, which can be indicated by the decreases in both the lengths of hospital stay and medical expenditures per case through the literatures. However, this system may produce the adverse outcomes within health care delivery due to insufficient, intentional, and cost-saving services. Furthermore, China has introduced this payment system since 1994, and needs to overcome the challenges through the gradual implementation process.
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Doege, Vanessa Martini Susanne. "Krankenhäuser auf dem Weg in den Wettbewerb : Der Implementierungsprozess der Diagnosis Related Groups /." Wiesbaden : Gabler Verlag / GWV Fachverlage GmbH, Wiesbaden, 2009. http://dx.doi.org/10.1007/978-3-8349-9979-5.

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Doege, Vanessa Martini Susanne. "Krankenhäuser auf dem Weg in den Wettbewerb : der Implementierungsprozess der Diagnosis Related Groups /." Wiesbaden : Gabler, 2008. http://d-nb.info/990564479/04.

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Books on the topic "Diagnosis related groups Victoria"

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Hirsh, Harold L. Diagnosis related groups: Course manual. [Washington, D.C.] (1120 20th St., NW, Washington 20036): Federal Publications, 1985.

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Casas, Mercè, and Miriam M. Wiley, eds. Diagnosis Related Groups in Europe. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9.

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Neal, Margo Creighton. Nursing diagnosis care plans for diagnosis-related groups. Boston: Jones & Bartlett, 1990.

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Mary, Paquette, and Mirch Mary, eds. Nursing diagnosis care plans for diagnosis-related groups. Venice, Calif: General Medical Publishers, 1990.

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Worthman, Linda G. Review of the literature on diagnosis related groups. Santa Monica, CA (P.O. Box 2138, Santa Monica 90406-2138): Rand, 1986.

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Hellinger, Fred J. Reimbursement under diagnosis-related groups: The Medicaid experience. [Washington, D.C.]: U.S. Dept. of Health and Human Services, Public Health Service, National Center for Health Services Research and Health Care Technology Assessment, 1986.

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1954-, Casas Mercè, and Wiley Miriam M, eds. Diagnosis related groups in Europe: Uses and perspectives. Berlin: Springer-Verlag, 1993.

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DRG Expert: A comprehensive guidebook to the MS-DRG classification system. 2nd ed. United States]: Ingenix, 2008.

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Reid, Beth A. The effect of coding on the allocation of diagnosis related groups. [Kensington, N.S.W. Australia: School of Health Services Management, University of New South Wales, 1991.

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Cotterill, Philip. Comparison of alternative relative weights for diagnosis-related groups. [Washington, D.C.?: Health Care Financing Administration, 1986.

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Book chapters on the topic "Diagnosis related groups Victoria"

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Iswanto, A. Heri. "Diagnosis-Related Groups." In Hospital Economics, 131–40. Boca Raton : Taylor & Francis, 2018. | “A CRC title, part of the Taylor & Francis imprint, a member of the Taylor & Francis Group, the academic division of T&F Informa plc.”: Productivity Press, 2018. http://dx.doi.org/10.4324/9781351172523-15.

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Wiedemann, Manfred. "DRG: Diagnosis Related Groups – Fallpauschalen." In Die Medizin verkauft ihre Seele, 49–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2020. http://dx.doi.org/10.1007/978-3-662-60956-9_6.

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France, Francis H. Roger. "Hospital Information Systems in Europe: Trends Towards Uniformity in Patient Record Summaries." In Diagnosis Related Groups in Europe, 3–16. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9_1.

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Vertrees, James C., and Kenneth G. Manton. "Using Case Mix for Resource Allocation." In Diagnosis Related Groups in Europe, 155–72. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9_10.

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Bentes, Margarida E., Joao A. Urbano, Maria Do Carmo Carvalho, and Maria S. Tranquada. "Using DRGs to Fund Hospitals in Portugal: An Evaluation of the Experience." In Diagnosis Related Groups in Europe, 173–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9_11.

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Ibern, Pere, James C. Vertrees, Kenneth G. Manton, and Max A. Woodbury. "Hospital Groups and Case-Mix Measurement for Resource Allocation and Payment." In Diagnosis Related Groups in Europe, 193–207. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9_12.

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Rodrigues, Jean-Marie. "DRGs: Origin and Dissemination Throughout Europe." In Diagnosis Related Groups in Europe, 17–29. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9_2.

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McGuire, Thomas E. "DRG Evolution." In Diagnosis Related Groups in Europe, 30–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9_3.

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Sanderson, Hugh F. "DRGs: How Well Do They Define Hospital Products in Europe?" In Diagnosis Related Groups in Europe, 46–60. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9_4.

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Casas, Mercè, and Rosa Tomàs. "Producing DRG Statistics at the European Level: Lessons from the EURODRG Project." In Diagnosis Related Groups in Europe, 63–80. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78472-9_5.

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Conference papers on the topic "Diagnosis related groups Victoria"

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Santana-Velasquez, Angelower, M. John Freddy Duitama, and Julian D. Arias-Londono. "Classification of Diagnosis-Related Groups using Computational Intelligence Techniques." In 2020 IEEE Colombian Conference on Applications of Computational Intelligence (ColCACI). IEEE, 2020. http://dx.doi.org/10.1109/colcaci50549.2020.9247889.

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Delhumeau, Cecile, Jacques Demongeot, Carole Langlois, and Carla Taramasco. "Modelling Medical Time and Expertise. Example of the Hospital Stay Duration in  Diagnosis Related Groups Data Bases." In 2009 International Conference on Complex, Intelligent and Software Intensive Systems (CISIS). IEEE, 2009. http://dx.doi.org/10.1109/cisis.2009.84.

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Socher, Karen, Douglas Nunes, Deborah Lopes, Artur Coutinho, Daniele Faria, Paula Squarzoni, Geraldo Busatto Filho, Carlos Buchpighel, Ricardo Nitrini,, and Sonia Brucki. "VISUAL MEDIAL TEMPORAL ATROPHY SCALES IN CLINICIAN PRACTICE." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda102.

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Background: Visual atrophy scales from the medial temporal region are auxiliary biomarker methods in Alzheimer’s Disease(AD).They may correlated with progression from preclinical to clinical AD. Objective: We aimed to compare medial temporal lobe atrophy (MTA) and entorhinal cortex atrophy (ERICA) scales for magnetic resonance image as a useful tool for probable AD diagnosis and evaluate their accuracy, sensitivity and specificity, regarding clinical diagnosis and 11C-PIB-PET. Methods: 2 neurologists blinded to diagnosis classified 113 adults (over 65y) through MTA and ERICA scales and correlated with sociodemographic data, amyloid brain cortical burden through the 11C-PIB-PET and clinical cognitive status, divided into 30 cognitive unimpaired (CU) individuals, 52 MCI and 31 dementia compatible with AD (DCAD). Results: Inter-rater reliability of these atrophy scales was excellent (0.8- 1) by Cohen analysis. CU group had significantly lower MTA scores (median value 0) than ERICA (median value 1)for both hemispheres. 11C-PIB-PET was positive in 45% of the whole sample. In MCI and DCAD groups, ERICA depicted greater sensitivity and MTA greater specificity. Accuracy was under 70% for both scores in all clinical groups. Conclusion: Our study achieved a moderate sensitivity for ERICA score and could be a better screening tool for DCAD or MCI than MTA score. But, none of them could be considered a useful biomarker in preclinical AD.
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Maffioletti, Virgínia Lúcia, Maria Alice Baptista, Felipe Silva, Valeska Marinho, Maria Cavalcanti, and Marcia Cristina Dourado. "DAY CENTER FOR PEOPLE WITH DEMENTIA: A RETROSPECTIVE STUDY ON ADHERENCE." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda032.

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Background: Evidence shows that day centers (DC) are an effective technology to support people with dementia (PwD) and their family caregivers (FC). Objective: To assess the mediators of adherence to treatment for PwD attended in DC. Methods: Retrospective study with a sample of 143 PwD who attended a DC between May 1998 and March 2020. The sample was divided into 4 groups by period of attendance. A descriptive and comparative analysis of sociodemographic factors and disease severity (CDR) at admission was performed. Results: The mean usage rate was 43.36 months. Most PwD started treatment at CDR2, had more than 8 years of schooling and were cared for by their spouses or children. Most FC had more than 8 years of schooling. The main reasons for discharge were worsening and death, and only 2% were institutionalized. There was no difference between groups in diagnosis, gender and PwD and FC schooling. From group that attended the DC for more than 36 months, 60% were married, 60% were cared for by their spouses, 41% were cared for by their children, and most had more than 8 years of schooling. Conclusion: The early start of treatment, being cared for by the spouse or children were mediators of treatment adherence. Education appears as a mediator in the search for treatment. The longevity of treatment and the low institutionalization rate suggest that the DC is a support device for PwD and their FC.
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Formoso, Carolina Rodrigue, Raphael Machado Castilhos, Wyllians Vendramini Borelli, Matheus Zschornack Strelow, and Marcia Fagundes Chaves. "ANTICHOLINERGIC BURDEN IN DEMENTIA." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda031.

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Background: The anticholinergic burden is associated with a greater risk of functional/ cognitive decline and morbidity/mortality. Objectives: Our aim was to quantify the anticholinergic burden in the first visit in our dementia tertiary outpatient clinic. Methods: We performed a retrospective analysis of all first visit medical records of patients referred from primary health care to the outpatient dementia clinic of a tertiary hospital in Porto Alegre with a final diagnosis of dementia or Mild Cognitive Impairment (MCI) between 2014-2019. We evaluated all medications in use and we calculated a final score using Brazilian Anticholinergic Activity Drug (BAAD) score. This scale classified drugs according to its central anticholinergic activity from 1 to 3, with higher values indicating greater activity. The final score is the sum of the score for each drug. We divided the sample in two groups (score=0 and ⩾ 1) and performed a logist regression using age, sex, dementia diagnosis and MMSE as covariates. Results: We identified 199 final diagnoses of dementia (mostly Alzheimer’s Disease (AD) [45.2%]) and 39 of MCI. Most patients with dementia (76.4%) and MCI (74.3%) had at least a BAAD score = 1. Median (IQI) BAAD score was higher in VD, 4 (1.0-6.5). In the regression analysis, BAAD score was associated with MMSE, controlling for covariates. Conclusions: In our sample, the anticholinergic burden was high and correlated with dementia severity.
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Almeida, Eliane Borca, Geise Silva, Isabella Avolio, Camila Dias, Maíra Oliveira, Ricardo Nitrini, Sonia Brucki, and Eliane Miotto. "INVESTIGATION OF EPISODIC MEMORY DEFCITS IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT (MCI)." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda043.

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Background: MCI can be classified as amnestic (aMCI) or non-amnestic (naMCI). Patients with aMCI are at increased risk of developing Alzheimer’s disease (AD). The clinical diagnosis encompasses episodic memory decline with preservation of activities of daily living, in addition to possible changes in other cognitive domains. Nevertheless, there is a lack of studies in the Brazilian population comparing the performance of aMCI on different episodic memory tests. Objectives: This study investigated episodic memory alterations in patients with aMCI and healthy controls (HC) through population-validated tests. Methods: We included 54 individuals, 36 aMCI and 18 HC. The neuropsychological protocol included estimated total IQ [vocabulary and matrix reasoning], Logical Memory (LM), Visual Reproduction (VR) and Rey Auditory Verbal Learning Test (RAVLT). Results: Significant differences were found between the groups in LM delayed recall (p=0.048); Visual Memory immediate recall (p=0.002); Visual Memory delayed recall (p=0.006); RAVLT immediate recall (p=0.19); RAVLT delayed recall (p=0.006) and RAVLT recognition (p=0.001). Conclusions: aMCI patients showed significant cognitive deficits in all episodic memory tests, except for the LM immediate recall. These findings corroborate the international literature and indicate the possibility of identifying differential cognitive alterations in the MCI.
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Baptista, Maria Alice, Nathália Kimura, Isabel Lacerda, Felipe Silva, and Marcia Cristina Dourado. "YOUNG AND LATE ONSET DEMENTIA: HOW DO THEY DIFFER IN TERMS OF DOMAINS OF AWARENESS?" In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda042.

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Background: Young onset dementia (YOD) is a diagnosis given when the neurocognitive process sets in before 65 years age. The YOD dementia process poses specific challenges related to financial issues, work and social demands, marriage, and parenthood, including losses and shifting roles, care responsibilities, as well as prospects for the future. Those challenges might account for the difference in awareness between YOD and late onset dementia (LOD). Awareness can be defined as the recognition of changes caused by deficits related to the disease process, which may include the ability to recognize a specific deficit, the emotional response to the difficulties presented and the ability to understand the impact of the disease in activities of daily living Objectives: This study is designed to investigate differences in awareness of cognitive functioning and health condition, functional activity impairments, emotional state, and social functioning and relationships among people with young onset (YOD) and late onset dementia (LOD); and examine associations between awareness and its domains with cognition, functionality, neuropsychiatric symptoms, social and emotional functioning and quality of life (QoL) in both groups. Methods: This is a cross-sectional design study. A group of 136 people with dementia and their respective caregivers (YOD = 50 and LOD = 86) were consecutively selected from an Alzheimer’s disease outpatient unit in Rio de Janeiro, Brazil. We assessed awareness of disease, dementia severity, cognition, functionality, neuropsychiatric symptoms, social and emotional functioning, and quality of life. Results: People with YOD were more aware of disease (total score), more aware of their cognitive functioning and health condition and of their functional activity impairments than people with LOD, even if this group was more severely cognitive impaired and had a worse level of functionality than LOD group. Besides, people with YOD had more neuropsychiatric symptoms than people with LOD. Multivariate linear regressions showed that functionality has a wide relationship to awareness for people with YOD. While neuropsychiatric symptoms and quality of life has a greater relation to awareness for people with LOD. Conclusions Different clinical variables are associated to different domains in YOD and LOD groups, reinforcing the heterogeneity of awareness in dementia.
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Cecato, Juliana, and Livia Galeote. "SENILITY AND COGNITIVE PERFORMANCE: ANALYSIS OF WECHSLER SCALE IN ELDERLY WITH MAJOR NEUROCOGNITIVE DISORDER." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda074.

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Background: CHC theory is a hierarchical model of intelligence, organized through cognitive skills and dividing the construct into crystallized and fluid. Objective: To describe the correlation among crystallized and fluid abilities in healthy people diagnosed with dementia. Methods: 45 subjects with 50 to 89 years old and at least 1 year of schooling. They were submitted to a detailed clinical interview and, later, to a neuropsychological evaluation. RAVLT, Wechsler Intelligence Scale (WAIS-III or WASI) and FDT were applied. Sample was divided into 2 groups: healthy elderly (without cognitive and functional decline) and those diagnosed with dementia (GE). The diagnosis of dementia was based on the DSM-5. Results: RAVLT and the Wechsler Scale differentiated HE from DG (p <0.0001). FDT did not show a statistically significant difference in the Counting, Reading and Inhibition items, showing that tasks involve time were not able to differentiate healthy individuals from DG. To compare the performance IQ it is evident that the performance in fluid skills is less effective, when compared to the crystallized items (IQ verbal), in differentiating healthy subjects from dementia. Conclusion: Tasks involving learning, delayed recall memory and recognition, that is, crystallized tasks, are more effective in differentiating dementia when compared to fluid tasks (processing speed).
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Brum, Wagner, Andrei Bieger, Joao Pedro Ferrari Souza, Marco de Bastiani, Andrea Benedet, Nicholas Ashton, Tharick Pascoal, et al. "A THREE-RANGE APPROACH ENHANCES PROGNOSTIC UTILITY OF CSF BIOMARKERS IN ALZHEIMER’S DISEASE." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda022.

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Background: Alzheimer’s disease (AD) was biologically defined by the 2018 NIA-AA Research Framework (RF), which recommends dichotomously defining biomarker status as normal or abnormal with single cutpoints. However, a three-range approach remains unexplored in AD fluid biomarkers. Objective: To assess the prognostic utility of a three-range approach for CSF biomarkers in AD. Methods: We included 1278 non-demented individuals (CU: n=575; MCI: n=703) from the ADNI with baseline CSF Elecsys® biomarkers. Within it, we defined three-range cutpoints with two-graph receiver operating characteristics (TGROC) for each CSF biomarker (Aβ1-42, p-tau, p-tau/Aβ1-42), based on amyloid PET positivity. Then, linear mixed-effects and Cox proportional hazards models were used to estimate longitudinal cognitive trajectories and risk of clinical progression based on CSF biomarker status. Hereby derived three-range cutpoints were compared to previously described binary thresholds for the same biomarkers. Power analyses for simulated trials were also carried. Results: We observed dynamic amyloid-PET changes for participants in the intermediate range, while a static profile for clearly normal and abnormal groups. Longitudinally, our approach revealed a divergent intermediate cognitive trajectory undetected by dichotomization, with power analyses demonstrating potential applications for trial enrichment. Conclusion: The proposed approach can improve CSF-based diagnosis, refine prognostic assessment and enhance clinical trial recruitment.
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Ciarlini, Bruna, Flávia E. Silva, Álissa Moura, Emmanuelle Sobreira, Roberto Paiva, Norberto Frota, and Fernanda Carvalho. "ACCUMBENS AREA MAY PLAY A ROLE IN FACIAL RECOGNITION OF EMOTIONS IN A LOW-EDUCATED POPULATION WITH MILD ALZHEIMER’S DISEASE." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda064.

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Background: There is no consensus on how recognition of universal facial emotions can be affected in low-educated individuals with Alzheimer’s Disease (AD). Objective: To assess the performance of Facial Recognition of Emotions Test (FERT) and to correlate with patterns of cortical atrophy measured through Voxel-Based Morphometry (VBM) in low-educated individuals with mild AD dementia compared to cognitively healthy people. Methods: Retrospective cohort of 24 adult volunteers with 4 years of schooling or less were included. Among them, 13 participants had a diagnosis of mild AD. Data obtained by VBM and FERT result were correlated. Results: AD group had a worse performance in the total FERT score (p <0.001). There was a statistically significant difference in the recognition of surprise, disgust and neutrality (p <0.001). A more intense and consistent correlation was observed between the volume of the Accumbens Area (AA) and FERT performance in the total group (r=0.817 and p <0.05). This correlation remained significant for emotion “disgust” only in the AD group (r=0.769 and p <0.05). Conclusion: We found a significant difference in the recognition of surprise, disgust and neutral emotions between groups. The brain region that was most associated with these emotions was the AA, with greater consistency in the difficulty in recognizing the emotion of disgust, in the AD.
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