Academic literature on the topic 'Diabetes – Risk factors'

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Journal articles on the topic "Diabetes – Risk factors"

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Almotairi, Faheed Mothib. "Management of Diabetes Mellitus, Risk Factors and Complications." International Journal Of Pharmaceutical And Bio-Medical Science 02, no. 10 (November 7, 2022): 462–65. http://dx.doi.org/10.47191/ijpbms/v2-i10-15.

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Chronic progressive metabolic problem and chronic hyperglycemia caused by a dysregulation of protein, lipid, and carbohydrate metabolism are two symptoms of diabetes mellitus, a complicated condition. Verapamil belongs to a group of calcium channel blockers that are not dihydropyridines. It works by preventing calcium from entering beta cells' cytoplasm, preventing the second phase of insulin release driven by glucose, as well as sulfonylurea and glucagon. Nephropathy, neuropathy, and retinopathy are examples of microvascular consequences of diabetes mellitus (cardiovascular and cerebrovascular disease). In both kinds of diabetes mellitus, higher urine albumin excretion (proteinuria) or decreased kidney glomerular filtration rate are symptoms of diabetic nephropathy, a microvascular consequence. By lowering patients' blood sugar levels and reducing their risk of cardiovascular disease, diabetes mellitus therapy aims to reduce mortality, delay the onset of disease complications, and slow the disease's progression. Metformin increases peripheral glucose utilization, liver, muscle, and adipose tissue sensitivity to insulin, inhibits gluconeogenesis, and reduces glucose absorption from the gastrointestinal system.
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Bhuyan, K. C. "Identification of Risk Factors for Diabetes Disability among Bangladeshi Adults." Diabetes and Islet Biology 5, no. 1 (January 11, 2022): 01–07. http://dx.doi.org/10.31579/2641-8975/027.

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The paper was to throw some light on the risk factors for diabetes disability among Bangladeshi adults of 18 years and above residing in both urban and rural areas. In investigating the adults, it was decided to cover 50.1% males and 49.9% females to maintain the national level of sex ratio in the sample. The respondents were interviewed when they were visiting some diagnostic centres in urban and semi-urban areas. The percentage of diabetic respondents included in the sample was 67% and 25.5% of them were suffering for 10 years and above, 6.4% were disable against 4.8% total disable respondents in the sample, and obese adults were 30.2%. Diabetic disable adults in the sample were 4.3%. The most responsible variable for diabetes disability was obesity followed by longer duration of diabetes, sedentary activity, smoking habit, being housewife, being married, etc. These variables were identified on the basis of risk ratio and correlation coefficients of variables and discriminant function scores. Beside these variables, rural people, Muslims, adults of ages 40 – 50 years, illiterate people had more risk of facing the problem of diabetes disability.
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AL-Banna, Haitham Issa, Zhian Salah Ramzi, and Rawa Jamil Mohammed. "RISK FACTORS OF TYPE 2 DIABETES MELLITUS IN SULAIMANI CITY." Journal of Sulaimani Medical College 7, no. 3 (November 1, 2017): 313–21. http://dx.doi.org/10.17656/jsmc.10134.

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Burden, Mary. "Diabetes-associated cardiovascular risk factors." Nursing Standard 15, no. 42 (July 4, 2001): 45–52. http://dx.doi.org/10.7748/ns2001.07.15.42.45.c3051.

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Lipman, Terri H., Mary McGrath Schucker, Sarah J. Ratcliffe, Tyler Holmberg, Scott Baier, and Janet A. Deatrick. "Diabetes Risk Factors in Children." MCN, The American Journal of Maternal/Child Nursing 36, no. 1 (January 2011): 56–62. http://dx.doi.org/10.1097/nmc.0b013e3181fc0d06.

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Escobar, Carlos, and Vivencio Barrios. "Risk Factors Control in Diabetes." Diabetes Educator 34, no. 5 (September 2008): 763–64. http://dx.doi.org/10.1177/0145721708325532.

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H. K Abdulwahab, Omed, and Rasul A. Rasul. "PREVALENCE AND RISK FACTORS OF MICROALBUMINURIA IN TYPE 2 DIABETES MELLITUS." Journal of Sulaimani Medical College 11, no. 3 (September 21, 2021): 343–50. http://dx.doi.org/10.17656/jsmc.10319.

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Maury-Mena, Sara Concepcion. "Psychosocial Risk Factors Associated with Gestational Diabetes Mellitus a Scoping Review." Journal of Quality in Health Care & Economics 5, no. 5 (2022): 1–24. http://dx.doi.org/10.23880/jqhe-16000299.

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Introduction: The prevalence of gestational diabetes mellitus (GDM) has increased worldwide and, of course, adverse outcomes for the health of the mother, fetus and neonate, and the resulting healthcare costs have increased. The World Health Organization affirms that healthy lifestyle habits that go with physical, mental, and psychosocial health and range from preconception to postpartum are essential to achieve successful pregnancies. Objective: Conducting a scoping review of the psychosocial risk factors associated with GDM. Materials and Methods: The databases consulted were PubMed / Medline and Cochrane. Studies on psychosocial risk factors in pregnant women older than 18 years, with a diagnosis of GDM, from 2010 to 2020, in English and Spanish, published in peer-reviewed journals, were selected. A standardized data extraction form was developed. Results: 1188 articles on this topic were found, 93 of which were selected according to the inclusion criteria. The findings yielded several main issues such as conflicts with cultural practices, social stigma, influence of ethnicity / race, low educational level, sleep quality, physical limitations, problems with breastfeeding, concern for the health of the mother and baby, low perception of risk of GDM and DM2 in the future, stress, anxiety and depression, limited knowledge about GDM, lack of partner / family / social support, low levels of self-care and self-efficacy in glycemic control, lack of support from health professionals and difficulties with changes in lifestyle. Discussion and Conclusion: All the identified psychosocial risk factors must be taken into account either by adapting existing prevention and promotion programs or by developing new programs. Interventions should not end with pregnancy and the psychological impact and risk of developing T2D after delivery should be considered, as well as multiethnic populations and the most demographically and socioeconomically vulnerable groups. In addition, they should be included in the Clinical Practice Guidelines and in prevention, promotion and intervention programs for the health and quality of life of women with GDM.
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Perišić, Marija Majda, Klemo Vladimir, Sarah Karpov, Mario Štorga, Ali Mostashari, and Raya Khanin. "Polygenic Risk Score and Risk Factors for Gestational Diabetes." Journal of Personalized Medicine 12, no. 9 (August 26, 2022): 1381. http://dx.doi.org/10.3390/jpm12091381.

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Gestational diabetes mellitus (GDM) is a common complication of pregnancy that adversely affects maternal and offspring health. A variety of risk factors, such as BMI and age, have been associated with increased risks of gestational diabetes. However, in many cases, gestational diabetes occurs in healthy nulliparous women with no obvious risk factors. Emerging data suggest that the tendency to develop gestational diabetes has genetic and environmental components. Here we develop a polygenic risk score for GDM and investigate relationships between its genetic architecture and genetically constructed risk factors and biomarkers. Our results demonstrate that the polygenic risk score can be used as an early screening tool that identifies women at higher risk of GDM before its onset allowing comprehensive monitoring and preventative programs to mitigate the risks.
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GEOGHEGAN, J. M., J. FORBES, D. I. CLARK, C. SMITH, and R. HUBBARD. "Dupuytren’s Disease Risk Factors." Journal of Hand Surgery 29, no. 5 (October 2004): 423–26. http://dx.doi.org/10.1016/j.jhsb.2004.06.006.

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Dupuytren’s is a common problem, but little is known about its a etiology. We have undertaken a large case-control study to assess and quantify the relative contributions of diabetes and epilepsy as risk factors for Dupuytren’s in the community. Cases were patients with a diagnosis of Dupuytren’s disease and, for each, two controls were individually matched by age, sex, and general practice. Our dataset included 821 cases and 1,642 controls. Five hundred and eighty-eight (72%) of the cases were men. The mean age at diagnosis was 62 (range 24–97) years. Diabetes was a significant risk factor for Dupuytren’s disease (OR = 1.75) and there was an increased risk for medicinally treated diabetes (metformin – R = 3.56; sulphonylureas – OR = 1.75) and particularly insulin controlled (OR = 4.39) rather than diet-controlled diabetes. Epilepsy (OR = 1.12) and antiepileptic medications were not associated with Dupuytren’s disease. Ascertainment bias in previous studies may explain the reported association with epilepsy.
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Dissertations / Theses on the topic "Diabetes – Risk factors"

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Orr, Neil John. "Patterns of care for diabetes: risk factors for vision-threatening retinopathy." Thesis, The University of Sydney, 2005. http://hdl.handle.net/2123/1421.

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OBJECTIVES: In Australia, diabetes causes significant morbidity and mortality. Whilst the need to prevent diabetes and its complications has been widely recognised, the capacity of health care systems - which organise diabetes care - to facilitate prevention has not been fully established. METHODS: A series of seven population-based case-control studies were used to examine the effectiveness of the Australian health care system and its capacity to manage diabetes. Six of the studies compared the patterns of care of patients who had developed advanced diabetes complications in 2000 (cases), to similar patients who remained free of the condition (controls) across Australia and for various risk groups. A secondary study investigated the role of treating GPs in the development of the outcome. RESULTS: A strong relationship between the patterns of care and the development of advanced diabetes complications was found and is described in Chapter 4. In Chapter 5, this same relationship was investigated for each Australian state and territory, and similar findings were made. The study in Chapter 6 investigated whether late diagnosis or the patterns of care was the stronger risk factor for advanced diabetes complications, finding that the greatest risk was associated with the latter. In Chapter 7 the influence of medical care during the pre-diagnosis period was explored, and a strong relationship between care obtained in this period and the development of advanced complications was found. In Chapter 8, which investigated the role of socio-economic status in the development of advanced complications, found that the risk of advanced diabetes complications was higher in low socio-economic groups. Chapter 9 investigated geographic isolation and the development of advanced diabetes complications and found that the risk of advanced complications was higher in geographically isolated populations. Finally, Chapter 10, which utilised a provider database, found that some GP characteristics were associated with the development of advanced diabetes complications in patients. CONCLUSION: A number of major risk factors for the development of advanced complications in Australia was found. These related to poorer diabetes management, later diagnosis, low socioeconomic status and geographic isolation. Strategies must be devised to promote effective diabetes management and the early diagnosis of diabetes across the Australian population.
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Orr, Neil John. "Patterns of care for diabetes: risk factors for vision-threatening retinopathy." University of Sydney, 2005. http://hdl.handle.net/2123/1421.

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Master of Public Health
OBJECTIVES: In Australia, diabetes causes significant morbidity and mortality. Whilst the need to prevent diabetes and its complications has been widely recognised, the capacity of health care systems - which organise diabetes care - to facilitate prevention has not been fully established. METHODS: A series of seven population-based case-control studies were used to examine the effectiveness of the Australian health care system and its capacity to manage diabetes. Six of the studies compared the patterns of care of patients who had developed advanced diabetes complications in 2000 (cases), to similar patients who remained free of the condition (controls) across Australia and for various risk groups. A secondary study investigated the role of treating GPs in the development of the outcome. RESULTS: A strong relationship between the patterns of care and the development of advanced diabetes complications was found and is described in Chapter 4. In Chapter 5, this same relationship was investigated for each Australian state and territory, and similar findings were made. The study in Chapter 6 investigated whether late diagnosis or the patterns of care was the stronger risk factor for advanced diabetes complications, finding that the greatest risk was associated with the latter. In Chapter 7 the influence of medical care during the pre-diagnosis period was explored, and a strong relationship between care obtained in this period and the development of advanced complications was found. In Chapter 8, which investigated the role of socio-economic status in the development of advanced complications, found that the risk of advanced diabetes complications was higher in low socio-economic groups. Chapter 9 investigated geographic isolation and the development of advanced diabetes complications and found that the risk of advanced complications was higher in geographically isolated populations. Finally, Chapter 10, which utilised a provider database, found that some GP characteristics were associated with the development of advanced diabetes complications in patients. CONCLUSION: A number of major risk factors for the development of advanced complications in Australia was found. These related to poorer diabetes management, later diagnosis, low socioeconomic status and geographic isolation. Strategies must be devised to promote effective diabetes management and the early diagnosis of diabetes across the Australian population.
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Chit, Moy Ley. "Bromelain and cardiovascular risk factors in diabetes." Thesis, London South Bank University, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631731.

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The rising prevalence of diabetes worldwide now ranks alongside smoking, high blood pressure and cholesterol disorder as an independent major risk factor for Cardiovascular Disease (CVD). Conventional therapy and dietary management using dietary supplements have been under consideration as measures to prevent or ameliorate the risk of developing complications of CVD in diabetes. A systematic review of the literature on bromelain (a pineapple enzyme) and CVD identified 7 animal studies and 3 human studies. Animal studies were conducted more recently and showed more promising results on bromelain and CVD than human studies. Existing evidence derived from 3 human studies in the systematic review, carried out in the 1970’s despite poor study design and lacking appropriate information on trial outcomes suggested that bromelain may have an effect on CVD risk factors. This research was inconclusive. Potential mechanisms for bromelain suggested that it may be useful for reducing plasma fibrinogen, preventing aggregation of blood platelets, increasing fibrinolytic activity and acting as an anti-inflammatory agent which is closely related to the pathogenesis of CVD complications in diabetes. This indicated that research into bromelain may provide new insights to help reduce the risk factors associated with CVD complications for people with diabetes. A Randomized Controlled Trial (RCT) was initiated with the aim of assessing whether the dietary supplement (bromelain) had the potential to reduce plasma fibrinogen and other associated risk factors for CVD in diabetic patients. The RCT on 68 Chinese diabetic patients (32 males and 36 females; Han origin, mean age of 61.26 years (Standard Deviation, SD 12.62 years)) with at least one risk factor of CVD demonstrated that 12-week intervention of 1.05g/day bromelain failed to show a beneficial effect in reducing fibrinogen and other CVD risk factors such as blood lipids, blood glucose, C-Reactive Protein (CRP), anthropometric indicators and blood pressure. A placebo-controlled trial with a larger sample size with higher fibrinogen levels and/or individuals at greater risk of developing CVD would be needed in a future study. Exploring bromelain’s effect on inflammatory markers which could be a possible underlying mechanism in the pathogenesis of CVD in diabetes, may be a more fruitful focus for future research.
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Morgan, Eileen. "Type 1 diabetes - epidemiology, risk factors and complications." Thesis, Queen's University Belfast, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678213.

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This thesis examined the incidence and temporal trends of Type 1 diabetes diagnosed in Northern Ireland children using data from the Northern Ireland Childhood Diabetes Register (NICDR). Overall, there was evidence of a departure from linearity in incidence with indications that rates are levelling off in recent years. Further analyses also indicated that birth cohort effects were evident in the incidence rates suggesting that exposures in early life may play an aetiological role in this condition. A systematic review and meta-analyses was performed in this thesis to investigate the association of childhood vaccinations and subsequent risk of Type 1 diabetes. Twelve studies investigating a range of vaccinations were included. Results provided no evidence to suggest an association between childhood vaccinations and risk of Type 1 diabetes. A study using data from the Clinical Practice Research Datalink (CPRD) was included in this thesis to report findings on depression and other complications in young people diagnosed with Type 1 diabetes. This study found that rates of depression were significantly higher in cases with diabetes compared to controls without diabetes. Results also showed elevated rates of microvascular complications and significantly higher rates of cardiovascular disease compared to matched controls. Another focus of this thesis was on mortality in individuals with Type 1 diabetes. Population-based studies reporting relative mortality in Type 1 diabetes diagnosed in young people were systematically reviewed. In total, 23 independent studies were included. Associations between relative mortality and study/ country characteristics were explored. In addition to this review, a further two UK-based studies were performed to investigate mortality, one using data from the NICDR and the other using the CPRD. Both studies found excess mortality rates in individuals with Type 1 diabetes when compared, respectively, to the general population and to a group of controls without diabetes.
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Becerra, Tomás Nerea. "Dietary factors associated with metabolic syndrome and type 2 diabetes risk." Doctoral thesis, Universitat Rovira i Virgili, 2017. http://hdl.handle.net/10803/460757.

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S’ha observat que els patrons dietètics s’associen de forma diferent al risc de desenvolupar la síndrome metabòlica (SM) i la diabetis tipus 2 (DT2). Amb l’objectiu d’entendre millor els diferents efectes dels patrons dietètics sobre el risc de desenvolupar aquestes malalties, és important analitzar el paper que juguen determinats grups d’aliments sobre el risc de desenvolupar el SM i la DT2. L’objectiu de la present tesis ha estat avaluar l’associació entre el consum de carn, productes làctics i el risc d’incidència de SM o alguns dels seus components, així com avaluar l’associació entre el consum de llegums i el risc de desenvolupar DT2. Els resultats van mostrar una associació inversa no significativa entre el consum total de productes làctics i el risc d’incidència de SM. El consum de productes làctics baixos en greix, llet descremada i iogurt (total, baix en greix i sencer) es va associar a un menor risc de SM i algun dels seus components. Contràriament, el consum de formatge es va associar a un major risc. De la mateixa manera, el consum de carn total també es va associar amb el risc de patir SM i algun dels seus components. Mentre que la carn vermella i la carn vermella processada es van associar a un menor risc de SM, el consum de carn blanca es va associar a un menor risc. Finalment, el consum de llegums totals, i en particular de llenties, es va associar a un menor risc d’incidència de DT2. En conclusió, un consum elevat de productes làctics baixos en greix i iogurt (independentment el seu contingut en greix), conjuntament amb el consum preferent de carn blanques en lloc de carns vermelles o carns vermelles processades, i una alta freqüència de llegums podria ser beneficiós per a la prevenció del SM i la DT2 en individus Mediterranis amb alt risc cardiovascular.
Se ha observado que los patrones dietéticos se asocian de manera distinta al riesgo de desarrollar síndrome metabólico (SM) y la diabetes tipo 2 (DT2). Con el objetivo de entender mejor los distintos efectos de los patrones dietéticos sobre el riesgo de desarrollar estas enfermedades, es importante analizar el papel que juegan determinados grupos de alimentos sobre el riesgo de desarrollar el SM y la DT2. El principal objetivo de la presente tesis ha sido evaluar la asociación entre el consumo de carne, productos lácteos y el riesgo de incidencia SM o alguno de sus componentes, así como evaluar la asociación entre el consumo de legumbres y el riesgo de desarrollar DT2. Los resultados mostraron una asociación inversa no significativa entre el consumo total de productos lácteos y el riesgo de incidencia de SM. El consumo de productos lácteos bajos en grasa, leche desnatada y yogur (total, bajo en grasa y entero) se asoció a un menor riesgo de SM y algunos de sus componentes. Contrariamente, el consumo de queso se asoció a un mayor riesgo. Del mismo modo, el consumo de carne total también se asoció con el riesgo de padecer SM y alguno de sus componentes. Mientras que la carne roja y la carne roja procesada se asociaron a un mayor riesgo de SM, el consumo de carne blanca se asoció a un menor riesgo. Finalmente, el consumo de legumbres totales, y en particular las lentejas, se asoció a un mejor riesgo de incidencia de DT2. En conclusión, un consumo elevado de productos lácteos bajos en grasa y yogur (independientemente del contenido en grasa), conjuntamente con consumo preferente de carnes blancas en lugar de carnes rojas o carnes rojas procesadas, y una alta frecuencia de legumbres, podría ser beneficioso para la prevención del SM y la DT2 en individuos Mediterráneos con alto riesgo cardiovascular.
It has been shown that dietary patterns are differently associated with the risk of metabolic syndrome (MetS) and type 2 diabetes (T2D). Whereas the Western diet seems to increase the risk of these chronic diseases, plant-based diets, such as the Mediterranean Diet (MedDiet), seem to decrease the risk. In order to better understand the different effects on disease risk among dietary patterns, it is important to analyze the role that specific food groups play on the risk of developing MetS and T2D. The main aim of the present dissertation was to evaluate the association between the consumption of meat and dairy products with the risk of MetS or the incidence of some of its individual components, as well as to assess the association between legumes consumption and T2D development risk. The results showed a non-significant inverse association between total dairy consumption and the risk of MetS incidence. The consumption of low-fat dairy products, low-fat milk and yogurt (total, low-fat and whole-fat yogurt) was associated with a lower risk of MetS and some of its individual components. Contrary, the consumption of cheese was positively associated with the MetS risk. Likewise, total meat intake was also associated with the risk of MetS and the development of some of its components. Whereas red meat and processed red meat were associated with a higher risk of MetS, poultry was associated with a lower risk. Finally, total legume consumption, particularly lentils, was associated with a lower risk of T2D incidence. In conclusion, high consumption of low-fat dairy products and yogurt (regardless the fat content), together with the preference for poultry rather than red meat or processed red meat, and high frequency consumption of legumes, would be beneficial for the prevention of MetS and T2D among Mediterranean individuals at high CVD risk.
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Hou, Wei Wei, and 侯薇薇. "Pubertal muscle mass and diabetes risks." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2015. http://hdl.handle.net/10722/208569.

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Type-2 diabetes is one of the most prevalent non-communicable diseases globally. The prevalence has increased rapidly in both developed and developing countries. Type-2 diabetes has become epidemic in China in the past three decades. With a relatively low obesity prevalence compared to western countries, such as the United States, the question has arisen as to why people in China are so susceptible to diabetes, but few studies have answered this question definitively. Asians have lower muscle mass than Caucasians which could be one possible explanation. This study aims to test the hypothesis that pubertal muscle mass acquisition, under the influence of testosterone, may be a risk factor for diabetes. This study recruited from the population-representative Chinese “Children of 1997” birth cohort with 8327 participants (88% of all infants born in April and May 1997) in Hong Kong. Participants were aged 15 years at the time of this study. The main objective was to examine the association of pubertal muscle mass with diabetes risk factors, and to examine determinants of pubertal muscle mass in this non-western setting. In June to August 2012, 502 participants from “Children of 1997” were recruited to complete a health assessment follow up at the Active Health Clinic in University of Hong Kong, including a questionnaire, blood tests and a physical examination. Multivariable linear regression was used to assess the associations of: (1) testosterone and pubertal muscle mass with diabetes risk factors, including fasting glucose, fasting insulin and homeostasis model assessment -insulin resistance (HOMA-IR), and any mediation of the association of testosterone with diabetes risk factors by pubertal muscle mass, and (2) environmental influences, including intergenerational influences, proxied by mother’s place of birth, and current life style influences (meat consumption and physical activity), with pubertal muscle mass. Higher pubertal testosterone was associated with lower fasting glucose (-0.008, 95% confidence interval (CI) -0.015 to -0.002), fasting insulin (-0.44, 95% CI -0.57 to -0.31) and HOMA-IR (-0.090, 95% CI -0.12 to -0.063) after adjusting for potential confounders, i.e, sex, birth weight, highest parental education, mother’s place of birth and physical activity. The association was partially mediated by skeletal muscle mass and body fat percentage. Skeletal muscle mass was negatively associated with fasting glucose (-0.017, 95% CI -0.025 to -0.009), insulin (-0.876, 95% CI -1.033 to -0.719), and HOMA-IR (-0.180, 95% CI -0.214 to -0.147) after adjusted for potential confounders. High meat consumption (0.176, 95% CI 0.000 to 0.351) and physical activity (0.157, 95% CI 0.059 to 0.254) were both associated with higher skeletal muscle mass in adolescents; however birth weight and mother’s place of birth had no influence on pubertal skeletal muscle composition. Higher pubertal muscle mass and testosterone are association with better glucose metabolism in adolescence. Food intake and physical activity may also influence the development of skeletal muscle, thus adolescence may be a sensitive period for the development of diabetes where interventions to increase muscle mass could have long-term protective effects.
published_or_final_version
Public Health
Master
Master of Philosophy
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Walldén, (Fredriksson) Jenny. "Studies of immunological risk factors in type 1 diabetes." Doctoral thesis, Linköpings universitet, Pediatrik, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-12441.

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Background: Type 1 diabetes (T1D) is a chronic, autoimmune disease caused by a T cell mediated destruction of ß-cells in pancreas. The development of T1D is determined by a combination of genetic susceptibility genes and environmental factors involved in the pathogenesis of T1D. This thesis aimed to investigate diverse environmental and immunological risk factors associated with the development of T1D. This was accomplished by comparing autoantibody development, T cell responses and the function of CD4+CD25+ regulatory T cells between healthy children, children at risk of T1D and T1D patients. Results: Induction of autoantibodies in as young children as one year old, was associated with previously identified environmental risk factors of T1D, such as maternal gastroenteritis during pregnancy and early introduction of cow’s milk. We did not see any general increase in the activity of peripheral blood TH subtypes in children with HLA class II risk haplotypes associated with T1D, nor were HLA class II risk haplotypes associated with any aberrant cytokine production in response to antigenic stimulation of peripheral blood mononuclear cells. However children with a HLA class II protective haplotype showed an increased production of IFN-γ in response to enteroviral stimulation. CTLA-4 polymorphisms connected with a risk of autoimmune disease were associated with enhanced production of IFN-γ. Healthy children with ß-cell autoantibodies had a lower expression level of GATA-3 compared to health children with HLA risk genotype or children without risk. Instead, children with manifest T1D showed lower expression levels of T-bet, IL-12Rß1 and IL-4Rα. Both T1D and healthy children showed the same expression of the regulatory markers Foxp3, CTLA-4 and ICOS in peripheral blood mononuclear cells, and the amount of CD4+CD25+ T cells did neither reveal any differences. The regulatory T cells seemed also to be functional in children with T1D, since increased proliferation after depletion of CD4+CD25high cells from PBMC was demonstrated in T1D as well as in healthy children.However, T1D children did have more intracellular CTLA-4 per CD4+CD25high T cell, increased levels of serum C-reactive protein and higher spontaneous expression of IFN-α in CD25depleted PBMC, all which are signs of activation of the immune system. This suggests a normal or enhanced functional activity of regulatory T cells in T1D at diagnosis. Conclusions: Our findings emphasize that environmental risk factors do have a role in the development of ß-cell autoimmunity. Our results do not support a systemic activation of the immune system in pre-diabetes or T1D, but instead a possible up-regulation of regulatory mechanisms seems to occur after diagnosis of T1D, which probably tries to dampen the autoimmune reaction taking place.
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Walldén, Jenny. "Studies of immunological risk factors in type 1 diabetes /." Linköping : Department of Clinical and Experimental Medicine, Linköping University, 2008. http://www.bibl.liu.se/liupubl/disp/disp2008/med1075s.pdf.

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Pettigrew, Kerry A. "Association studies to identify genetic risk factors for diabetic nephropathy in type 1 diabetes." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.479350.

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Penishkevych, Ya I., O. P. Kuchuk, O. O. Kuzio, and S. V. Tymofiychuk. "Risk factors for progression of diabetic retinopathy in patients with type 2 diabetes mellitus." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/16914.

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Books on the topic "Diabetes – Risk factors"

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Louisiana. Office of Public Health. Diabetes Prevention and Control Program. Louisiana diabetes report. 2nd ed. Baton Rouge, La: Louisiana Dept. of Health and Hospitals, 2010.

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Massachusetts. Bureau of Health Statistics, Research and Evaluation. Diabetes in Massachusetts: Results from the behavioral risk factor surveillance system 1994-1996. [Boston, Mass.]: The Bureaus, 1998.

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Roth, Rivkah. At risk?: Avoid diabetes by recognizing early risk : a natural medicine view. Toronto: NMC Pub., 2008.

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Roth, Rivkah. At risk?: Avoid diabetes by recognizing early risk : a natural medicine view. [Bloomington, Ind.?]: Xlibris, 2008.

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At risk?: Avoid diabetes by recognizing early risk : a natural medicine view. Toronto: NMC Pub., 2008.

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Reducing cardiovascular risk in people with diabetes mellitus. Dartford: Magister Consulting, 2006.

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Project, Montana Diabetes. Diabetes: The burden in Montana. Helena, Mont: Montana Dept. of Public Health & Human Services, 2009.

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Templeton, Mardi. Gestational diabetes mellitus in Australia, 2005-06. Canberra: Australian Institute of Health and Welfare, 2008.

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Rayfield, Elliot J. Diabetes, beating the odds: The doctor's guide to reducing your risk. Reading, Mass: Addison-Wesley, 1992.

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Thow, Anne Marie. Diabetes in culturally and linguistically diverse Australians: Identification of communities at high risk. Canberra: Australian Institute of Health and Welfare, 2005.

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Book chapters on the topic "Diabetes – Risk factors"

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Nilsson, Peter M., Adie Viljoen, and Anthony S. Wierzbicki. "Cardiovascular Risk Factors." In Textbook of Diabetes, 657–83. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444324808.ch40.

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Nilsson, Peter M. "Cardiovascular Risk Factors: Hypertension." In Textbook of Diabetes, 629–42. Chichester, UK: John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118924853.ch42.

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Moini, Jahangir, Matthew Adams, and Anthony LoGalbo. "Prevalence, Mortality, and Risk Factors." In Complications of Diabetes Mellitus, 24–30. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003226727-3.

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Stout, Robert W. "Risk Factors for Atherosclerosis in Diabetes Mellitus." In Diabetes and Atherosclerosis, 89–109. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2734-9_5.

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Böger, Carsten A., and Peter R. Mertens. "Genetic Risk Factors for Diabetic Nephropathy." In Diabetes and Kidney Disease, 29–44. Oxford, UK: Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781118494073.ch3.

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Kim, Hae Kyung, and Byung-Wan Lee. "Pathophysiology and Risk Factors of Diabetes." In Stroke Revisited, 15–24. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-5123-6_2.

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Oates, Thomas W., Alyssa Dierkes, Katherine Ni, and Hanae Saito. "Diabetes as a Systemic Factor for Peri-implantitis." In Risk Factors for Peri-implant Diseases, 59–67. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39185-0_6.

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Neal, William A., Collin John, and Alia Rai. "Cardiovascular Risk Factors: Obesity, Diabetes, and Lipids." In Pediatric Cardiovascular Medicine, 954–62. Oxford, UK: Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781444398786.ch65.

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Tentolouris, Anastasios, and Nikolaos Tentolouris. "Risk Factors for Developing Gestational Diabetes Mellitus." In Comprehensive Clinical Approach to Diabetes During Pregnancy, 53–71. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-89243-2_4.

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Chandalia, Manisha, and Prakash C. Deedwania. "Coronary Heart Disease and Risk Factors in Asian Indians." In Diabetes and Cardiovascular Disease, 27–34. Boston, MA: Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1321-6_5.

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Conference papers on the topic "Diabetes – Risk factors"

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Nugroho, Trilaksana, Hari Peni Julianti, Arief Wildan, rnila Novitasari Saubig, Andhika Guna Darma, and Desti Putri Seyorini. "Risk Factor of Dry Eyes Syndrome Toward Elderly with Diabetes Mellitus." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.05.26.

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ABSTRACT Background: Chronic metabolic disorder diabetes is a rapidly developing global problem with huge social, health and economic consequences. Indonesia is expected to reach 21.3 million people by 2030, and the incidence of diabetes is still increasing. Type 2 diabetes (T2DM) is an expanding global health problem closely related to the obesity epidemic. Type 2 diabetes (T2DM) is an expanding global health problem closely related to the obesity epidemic. Prolonged diabetes mellitus (DM) causes autonomic neuropathy in the lacrimal glands, which leads to reduced tear production, leading to dry eye syndrome (DES). This study aimed to analyze risk factor of dry eyes syndrome toward elderly with diabetes mellitus. Subjects and Method: A cross sectional study was conducted at community health center Gunungpati and Graha Syifa clinic, Semarang. A sample of 28 elderlies was selected by consecutive sampling. The dependent variable was incidence of DES. The independent variables were gender, duration of DM, DM control, incidence of diabetic retinopathy, type of work, exposure to cigarette smoke, exposure to gadgets, incidence of hypertension, incidence of dyslipidemia, incidence of cataracts. The data were collected by examination, questionnaire and in-depth interview. The data were analyzed by logistic regression and Chi square. Results: The logistic regression test results showed that gender, (p = 0.393), duration of diabetes (p = 0.208), and the incidence of diabetic retinopathy (p = 0.264) were not risk factors for DES. The results of the logistic regression test showed that controlling diabetes (p = 0.002), gadget exposure (p = 0.023) were risk factors for DES incidence. DM control and gadget exposure contributed 75% as risk factors for DES events. Conclusion: Uncontrolled DM and exposure to gadgets> 2 hours continuously a day are risk factors for DES. Keywords: Dry eyes, Diabetes Mellitus, Elderly Correspondence: Trilaksana Nugroho. Faculty of Medicine, Universitas Diponegoro. Jl. Prof. Sudarto No.13, Tembalang, Kec. Tembalang, Kota Semarang, Jawa Tengah 50275. DOI: https://doi.org/10.26911/the7thicph.05.26
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Yenti, Sesrima, Nur Alvira Pasca Wati, and Ayu Fitriani. "RISK FACTORS OF TYPE 2 DIABETES MELLITUS IN YOGYAKARTA." In International Conference on Public Health. Masters Program in Public Health, Sebelas Maret University, 2017. http://dx.doi.org/10.26911/theicph.2017.042.

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Musleh, Saleh, Tanvir Alam, Abdesselam Bouzerdoum, Samir B. Belhaouari, and Hamza Baali. "Identification of Potential Risk Factors of Diabetes for the Qatari Population." In 2020 IEEE International Conference on Informatics, IoT, and Enabling Technologies (ICIoT). IEEE, 2020. http://dx.doi.org/10.1109/iciot48696.2020.9089545.

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Boyle, P., M. Boniol, A. Koechlin, M. Bota, C. Robertson, D. Leroith, J. Rosenstock, GB Bolli, and P. Autier. "Abstract P4-13-08: Diabetes, Related Factors and Breast Cancer Risk." In Abstracts: Thirty-Fifth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 4‐8, 2012; San Antonio, TX. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/0008-5472.sabcs12-p4-13-08.

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TAVARES, Lívia Hygino, and Bruno MOURA. "DIABETES IN PREGNANCY AND FETAL CARDIAC RISK: LITERATURE REVIEW." In SOUTHERN BRAZILIAN JOURNAL OF CHEMISTRY 2021 INTERNATIONAL VIRTUAL CONFERENCE. DR. D. SCIENTIFIC CONSULTING, 2022. http://dx.doi.org/10.48141/sbjchem.21scon.45_abstract_tavares.pdf.

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Gestational diabetes mellitus (MGD) is associated with poor cardiac malformation in the fetus. It is related to changes in the clinical course of the disease and pre-gestational periods. The prevalence and incidence of MGD have been increasing worldwide. Early screening, diagnosis, and lifestyle change, such as physical exercise and healthy eating, provide better outcomes for children's health. This study aims to analyze the data concerning gestational diabetes and fetal malformations and to group the various protocols for diagnosis, highlighting the risk factors associated with MGD and their prevention. A systematic review of the literature was conducted with the PubMed, Scielo, Medline databases with English, Portuguese, and Spanish articles. The studies gathered clinical trials, randomized clinical trials, and original articles. In 12 articles analyzed maternal alterations, while 11 articles analyzed fetal alterations, and 9 articles analyzed how to diagnose cardiac changes in the fetus. The patient with MGD should be inserted in multidisciplinary activities seeking the change of lifestyle, physical exercises, and food reeducation, intending to give the fetus the appropriate nutrients and optimize the drug treatment; cardiac malformations are among the most severe and recurrent complications. However, they can be avoided with the control of pre-gestational diabetes (stricter follow-up from the moment the patient feels the desire to become pregnant) and the diagnosis and treatment of early gestational diabetes, as strict control of maternal blood glucose during pregnancy reduces morbidities and mortality. The study showed that hyperglycemic status during pregnancy is related to increased mortality and morbidity, even if it is asymptomatic. Therefore, it is necessary to guide the diabetic woman to plan her pregnancy in a euglycemic period because only this control can guarantee health to the fetus. The diagnosis of pregnant women with gestational diabetes needs to be early to optimize treatment.
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Zhu, Liang, and Robert Flower. "Role of Vasomotion in Control of Retina Edema in Diabetic Retinopathy: Quantification of Fluid Transport Through Retinal Capillaries." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-189507.

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Diabetic retinopathy refers to diabetes-related complications in the retina, It is a progressive disease and its symptoms in the eyes can vary from non-vision threatening to vision loss, and it can lead to permanent damage to the neuronal retinal tissue. The irreversible nature of the damage suggests that prevention of diabetes by eliminating risk factors and early screening are the cornerstone of relevant treatment to stop or limit visual damage in those patients.
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K, Dr Annapoorna, and Dr Latha K.S. "Effect of Yoga Therapy on Risk factors of Diabetes Mellitus - A Preventive Perspective." In Annual Global Healthcare Conference. Global Science & Technology Forum (GSTF), 2014. http://dx.doi.org/10.5176/2251-3833_ghc14.36.

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Chen, Hui, Yi Xin, Yuting Yang, Fei Li, Guoliang Cheng, and Xinxin Zhang. "Related Factors and Risk Prediction of Type 2 Diabetes Complicated with Liver Cancer." In 2019 IEEE International Conference on Mechatronics and Automation (ICMA). IEEE, 2019. http://dx.doi.org/10.1109/icma.2019.8816301.

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Abdulaimma, Basma, Abir Hussin, Paul Fergus, Dhiva Al-Jumeily, Paulo Lisboa, De-Shuang Huang, and Naeem Radi. "Improving Type 2 Diabetes Phenotypic Classification by Combining Genetics and Conventional Risk Factors." In 2018 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2018. http://dx.doi.org/10.1109/cec.2018.8477647.

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Rykov, S., S. Mohilevskyi, and S. Lytvynenko. "NEW RISK FACTORS FOR HEMOPHTHALMOS AFTER VITREORETINAL SURGERY IN CASES OF DIABETIC RETINOPATHY AND TYPE 2 DIABETES MELLITUS." In RICERCHE SCIENTIFICHE E METODI DELLA LORO REALIZZAZIONE: ESPERIENZA MONDIALE E REALTÀ DOMESTICHE. European Scientific Platform, 2021. http://dx.doi.org/10.36074/logos-26.11.2021.v3.27.

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Reports on the topic "Diabetes – Risk factors"

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Mellenthin, Claudia, Vasile Balaban, Ana Dugic, Stephane Cullati, and Bernhard Egger. Risk factors for pancreatic cancer in patients with new onset diabetes - Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2022. http://dx.doi.org/10.37766/inplasy2022.2.0065.

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Review question / Objective: Which additional risk factors raise the incidence of pancreatic cancer in the population of new onset diabetics? Condition being studied: Pancreatic cancer, new onset diabetes. Eligibility criteria: Inclusion criteria are:• English abstract available• The population of newly onset diabetics is examined, at least as a subgroup. Newly diagnosed is defined as onset of maximal 3 years ago.• Information on other risk factors of patients is available in the study.
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Wang, Kai, Peng Xu, Zhiguo Lv, Yabin Cui, Dongmei Zhang, Yibin Zhang, Xiaoxu San, and Jian Wang. Factors related to the risk of stroke in the population with type 2 diabetes: A meta-analysis and systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2021. http://dx.doi.org/10.37766/inplasy2021.6.0003.

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Wang, Kai, Zhiguo Lv, Peng Xu, Yabin Cui, Xiaoyu Zang, Dongmei Zhang, and Jian Wang. Factors related to the risk of stroke in the population with type 2 diabetes: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2021. http://dx.doi.org/10.37766/inplasy2021.10.0046.

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Li, Bin, Fei Wen, Hongru Chen, and Ri-Li Ge. A meta analysis of the prevalence rate of diabetic retinopathy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0112.

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Review question / Objective: P: diabetic retinopathy; I:—; C:—; O: prevalecne rate; S:cross-sectional study. Objective:To analyze the epidemiological characteristics of diabetic retinopathy and to provide scientific basis for its prevention and control. Condition being studied: Diabetic retinopathy is one of the common microvascular complications in patients with diabetes mellitus, which ultimately seriously affects the vision of patients. It is the leading cause of blindness among young and middle-aged workers worldwide. It is one of the main causes of binocular blindness in elderly patients in western countries.Because of the high incidence, wide range, complex pathogenesis, serious consequences and poor treatment effect of DM and its DR,many countries have actively carried out epidemiological research on the population of DM patients in order to understand the incidence, distribution and related risk factors of DR, and to provide scientific basis for the formulation of targeted public prevention and control measures.
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Zheng, Xing, Yingjun Cao, Fuzhong Xue, Aijun Wang, and Shucheng Si. The effects of Mediterranean-style diet on glycemic control, cardiovascular risk factors and weight loss in patients with type 2 diabetes: a meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2021. http://dx.doi.org/10.37766/inplasy2021.6.0096.

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Pu, Fenglan, Tianli Li, Yingqiao Wang, Chunmei Tang, Chen Shen, and Jianping Liu. Cordyceps preparations for preventing contrast-induced nephropathy: A protocol of systematic review of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0098.

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Review question / Objective: To systematically evaluate the efficacy and safety of cordyceps preparations as a complementary preventive therapy for Contrast-induced nephropathy (CIN). Condition being studied: At present, contrast agents are widely used in diagnostic and interventional radiology examinations worldwide. However, they can affect kidney function and cause a risk of renal impairment. Contrast-induced nephropathy (CIN) is defined as a rise in serum creatinine (SCr) levels by ≥ 25% of baseline or 44 µmol/l from the pre-contrast value within 72 h of intravascular administration of a contrast agent in the absence of an alternative etiology. The incidence of CIN varies widely among studies depending on study population and baseline risk factors, as for high-risk groups such as pre-existing renal insufficiency, diabetes, advanced age, or receiving nephrotoxic agents, the incidence is up to 30–50%. To date, CIN has been the third most common cause of hospital-acquired renal failure, after impaired renal perfusion and nephrotoxic medications, which can lead to longer hospital stay, increased costs and higher mortality.
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Zhou, Yujun, Qing Wang, Lin Lv, Hongyan Zhang, Dongli She, Long Ge, and Lin Han. Predictors of pressure injury in patients with hip fracture: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0028.

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Review question / Objective: The purpose of this study was to investigate the predictors of pressure injury in patients with hip fracture in order to provide a reference for clinical practice. Condition being studied: Hip fracture has become a major public health issue of common concern in both developed and developing countries. and its incidence is estimated to rise to 6.26 million by 2050. Hip fracture patients are prone to various complications during treatment and rehabilitation, and pressure injury (PI) is one of the common complications of hip fracture. Studies have reported that the incidence of pressure injury in patients with hip fracture is 3.4%-59.8%. In addition, pressure injury may occur at any time when patients with hip fracture are hospitalized, which not only greatly aggregates the pain of patients, but also increases the difficulty of treatment and nursing, and seriously threatens the safety of patients. Clarifying the influencing factors of pressure injury after hip fracture will help medical staff quickly identify high-risk patients and strengthen preventive measures. However, previous studies have only discussed the influence of individual factors on the occurrence of pressure injury in patients with hip fracture from the perspectives of diabetes and early surgery, and there is still a lack of systematic analysis on the influencing factors of pressure injury in patients with hip fracture.
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Rhim, Hye Chang, Jason Schon, Sean Scholwalter, Connie Hsu, Michael Andrew, Sarah Oh, and Daniel Daneshvar. Anterior versus posterior steroid injection approach for adhesive capsulitis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2023. http://dx.doi.org/10.37766/inplasy2023.1.0080.

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Review question / Objective: Which steroid injection approach is more effective, anterior or posterior, for adhesive capsulitis? The purpose of this review will be to compare the efficacy of anterior versus posterior steroid injection approach in adhesive capsulitis. Condition being studied: Adhesive capsulitis, or frozen shoulder, is a painful restriction of the glenohumeral joint, thought to be caused by inflammation of the synovial lining capsule and contracture of the glenohumeral joint. It is characterized by progressive shoulder pain with gradual loss of both passive and active range of motion. It is one of the most common musculoskeletal disorders treated by orthopedic surgeons with a prevalence of 25% in the general population, and risk factors include trauma, diabetes, stroke, and prolonged immobilization.
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Hou, Yuying, Yitong Cai, Zhumin Jia, and Suling Shi. Risk factors and Prevalence of Diabetic Retinopathy:A Protocol for Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2020. http://dx.doi.org/10.37766/inplasy2020.7.0107.

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Luan, Sisi, Wenke Cheng, Chenglong Wang, Hongjian Gong, and Jianbo Zhou. Impact of glucagon-like peptide 1 analogs on cognitive function among patients with type 2 diabetes mellitus. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0015.

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Review question / Objective: Diabetes is an independent risk factor for cognitive impairment. Little is known regarding the neuroprotective effects of glucagon-like peptide 1 (GLP-1) analogs on type 2 diabetes mellitus (T2DM).Here, the study aim to assess the impact of GLP-1 on general cognition function among patients with T2DM. Eligibility criteria: Inclusion criteria were as follows: (1) an original article was recently published in English, (2) the population included subjects diagnosed with diabetes at baseline, (3) GLP-1 analogs is a single formulation rather than a fixed dose combination, (4) GLP-1 analogs were compared with no GLP-1 use or placebo or self-control before treatment, (5) the duration of antidiabetic agent use was 12 weeks or more, and (6) it provided quantitative measures of general cognitive function assessed by MMSE or MoCA. Exclusion criteria were as follows: (1) the publication was a review, case report, animal study, or letter to the editor, (2) the study did not clearly define clinical outcomes, (3) the authors could not provide valid data after being contacted, (4) duplicated data.
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