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Journal articles on the topic 'DHSH'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

GRÜNWELLER, Arnold, Werner G. PURSCHKE, Sebastian KÜGLER, Charli KRUSE, and Peter K. MÜLLER. "Chicken vigilin gene: a distinctive pattern of hypersensitive sites is characteristic for its transcriptional activity." Biochemical Journal 326, no. 2 (September 1, 1997): 601–7. http://dx.doi.org/10.1042/bj3260601.

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Vigilin, a multidomain hn-ribonucleo-K-homologous protein, is part of a ribonucleoprotein complex with cognate tRNA and is found in both the nucleus and the cytoplasm. In an approach to identify genomic regions involved in regulation of the chicken vigilin gene, we carried out transfection studies with a reporter gene in suitable chicken cells. After including a distantly positioned 5′-sequence in the construct, we observed a 10.5-fold increase in luciferase (EC 1.13.12.7) expression compared with basal promoter activity. Accordingly, chromatin analysis of freshly isolated embryonic tendon fibroblasts with high levels of vigilin mRNA expression shows a DNase-I-hypersensitive site (DHS1) localized 2.2 kb upstream of the transcriptional start site. Similarly, phytohaemagglutinin-stimulated lymphocytes with a 4-fold elevated expression of vigilin mRNA compared with resting lymphocytes also exhibited this unique DHS, having switched from that found at 3.3 kb (DHS2) in resting lymphocytes. Furthermore, using gel-retardation experiments with DNA representing either DHS1 or DHS2, a specific interaction with chicken nuclear extracts was seen.

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2

Lomozová, Zuzana, Václav Tvrdý, Marcel Hrubša, Maria Carmen Catapano, Kateřina Macáková, David Biedermann, Radim Kučera, Vladimír Křen, Přemysl Mladěnka, and Kateřina Valentová. "Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo." Antioxidants 10, no. 5 (April 27, 2021): 679. http://dx.doi.org/10.3390/antiox10050679.

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2,3-Dehydrosilybin (DHS) was previously shown to chelate and reduce both copper and iron ions. In this study, similar experiments with 2,3-dehydrosilychristin (DHSCH) showed that this congener of DHS also chelates and reduces both metals. Statistical analysis pointed to some differences between both compounds: in general, DHS appeared to be a more potent iron and copper chelator, and a copper reducing agent under acidic conditions, while DHSCH was a more potent copper reducing agent under neutral conditions. In the next step, both DHS and DHSCH were tested for metal-based Fenton chemistry in vitro using HPLC with coulometric detection. Neither of these compounds were able to block the iron-based Fenton reaction and, in addition, they mostly intensified hydroxyl radical production. In the copper-based Fenton reaction, the effect of DHSCH was again prooxidant or neutral, while the effect of DHS was profoundly condition-dependent. DHS was even able to attenuate the reaction under some conditions. Interestingly, both compounds were strongly protective against the copper-triggered lysis of red blood cells, with DHSCH being more potent. The results from this study indicated that, notwithstanding the prooxidative effects of both dehydroflavonolignans, their in vivo effect could be protective.

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3

Poredoš, Kitanovski, and Poredoš. "Exergy Analyses of Low-Temperature District Heating Systems With Different Sanitary Hot-Water Boosters." Entropy 21, no. 4 (April 10, 2019): 388. http://dx.doi.org/10.3390/e21040388.

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This paper presents an exergy-efficiency analysis of low-temperature district heating systems (DHSs) with different sanitary hot-water (SHW) boosters. The required temperature of the sanitary hot water (SHW) was set to 50 °C. The main objective of this study was to compare the exergy efficiencies of a DHS without a booster to DHSs with three different types of boosters, i.e., electric-, gas-boiler- and heat-pump-based, during the winter and summer seasons. To achieve this, we developed a generalized model for the calculation of the exergy efficiency of a DHS with or without the booster. The results show that during the winter season, for a very low relative share of SHW production, the DHS without the booster exhibits favorable exergy efficiencies compared to the DHSs with boosters. By increasing this share, an intersection point above 45 °C for the supply temperatures, at which the higher exergy efficiency of a DHS with a booster prevails, can be identified. In the summer season the results show that a DHS without a booster at a supply temperature above 70 °C achieves lower exergy efficiencies compared to DHSs with boosters at supply temperatures above 40 °C. The results also show that ultra-low supply and return temperatures should be avoided for the DHSs with boosters, due to higher rates of entropy generation.

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4

Fujii, Shin, Takaaki Furubayashi, and Toshihiko Nakata. "Design and Analysis of District Heating Systems Utilizing Excess Heat in Japan." Energies 12, no. 7 (March 28, 2019): 1202. http://dx.doi.org/10.3390/en12071202.

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District heating systems (DHSs) which utilize excess heat play an important role in energy infrastructure in many European countries. In contrast to Europe, the DHS is not common and excess heat is not reused effectively in Japan. Almost all the DHSs in Japan were designed as first-generation district heating (1GDH) systems or 2GDH systems. No 4GDH systems have been introduced in Japan. The present study designs a 4GDH system utilizing excess heat from a wide area of Northern Japan and evaluates its feasibility. First, available heat amounts from two excess heat resources were calculated: waste incineration plants and thermal power plants. Second, heat demand from both residential and commercial sectors was estimated using a 1 km mesh, and a heat load curve was created for each mesh based on load curve data. Third, the DHS was designed with excess heat plants as a supply-side heat resource, and spatial information of the demand side made use of the geographical information system (GIS). Further analysis was conducted on selected DHSs in three cities in order to evaluate those systems’ feasibility based on energy efficiency, CO2 emissions, and economic aspects. The result shows that 70.5 PJ of heat can be supplied by DHS in Northern Japan, replacing imported fossil fuels such as petroleum and LPG with regional excess heat. The designed DHS could supply heat with equivalent costs compared to European countries.

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5

Sommer, Marc-Nicola, Dorian Bevec, Bert Klebl, Birgit Flicke, Kerstin Hölscher, Tatjana Freudenreich, Ilona Hauber, Joachim Hauber, and Helmut Mett. "Screening Assay for the Identification of Deoxyhypusine Synthase Inhibitors." Journal of Biomolecular Screening 9, no. 5 (August 2004): 434–38. http://dx.doi.org/10.1177/1087057104264031.

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The 1st step in the posttranslational hypusine [Nε-(4-amino-2-hydroxybutyl)lysine] modification of eukaryotic translation initiation factor 5A (eIF5A) is catalyzed by deoxyhypusine synthase (DHS). The eIF5A intermediate is subsequently hydroxylated by deoxyhypusine hydroxylase (DHH), thereby converting the eIF5A precursor into a biologically active protein. Depletion of eIF5A causes inhibition of cell growth, and the identification of eIF5A as a cofactor of the HIV Rev protein turns this host protein and therefore DHS into an interesting target for drugs against abnormal cell growth and/or HIV replication. The authors developed a 96-well format DHS assay applicable for the screening of DHS inhibitors. Using this assay, they demonstrate DHS inhibition by AXD455 (Semapimod, CNI-1493). This assay represents a powerful tool for the identification of new DHS inhibitors with potency against cancer and HIV.

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6

Fang, Xiangdong, Kai-Hsin Chang, Daniel Bates, Morgan Diegel, Richard Sandstrom, Molly Weaver, Michael O. Dorschner, et al. "Chromatin Profiling of the Globin Loci of Human ES Cells and ES-Derived Erythroid Cells." Blood 114, no. 22 (November 20, 2009): 2535. http://dx.doi.org/10.1182/blood.v114.22.2535.2535.

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Abstract Abstract 2535 Poster Board II-512 We used a high throughput approach to determine the chromatin profiles of the human β and α globin loci and their upstream and downstream regions in human undifferentiated ES cells, ES cell-derived erythroid cells, human fetal and adult origin erythroid cells and in primary cells and cell lines of endo-meso and ectodermal origins. All DNase I hypersensitive sites of the b-locus were absent in undifferentiated human ES cells except for HS2 of the b-globin locus control region. The chromatin profiles of the β and α globin loci of ES cell-derived erythroid cells were identical to those of fetal liver erythroid cells except that the hypersensitive site of the embryonic globin gene was more prominent. DNase I hypersensitive site 2 of the b-globin LCR, a potent enhancer, was present in all the cell lines and primary lineages we studied, providing direct evidence that it is ubiquitous. Several new erythroid specific DHSs were detected upstream of 5′HS7 of the β-LCR, raising the possibility that they play a role in the regulation of the β globin locus. The region downstream to 3′HS1 was depleted of DHSs except for the previously identified DHS mapping near the breakpoint of HPFH 1. Since DHSs are absent near the breakpoints of deletional HPFHs and db thalassemias and since enhancers are typically DHS positive, our results argue against the hypothesis of imported enhancers in the pathogenesis of deletional HPFH and db thalassemia mutants. All the previously identified erythroid specific DHSs of the α globin locus were absent in human ES cells. The α globin locus of ES cells, however, displayed three very prominent DHSs, which were located almost symmetrically about 40 Kb apart from each other and they were constitutively formed in all the lineages and cell lines we have studied; the 3′ and 5′ DHSs carried CTCF sites by ChIP-Seq assay raising the possibility that they mark the sites of chromatin insulators. Overall these results demonstrate the power of the new high throughput chromatin profiling approaches and their ability to uncover features of chromatin that may be of regulatory relevance. Disclosures: No relevant conflicts of interest to declare.

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7

NUTHALL, Hugh N., Danielle S. MOULIN, Clare HUXLEY, and Ann HARRIS. "Analysis of DNase-I-hypersensitive sites at the 3′ end of the cystic fibrosis transmembrane conductance regulator gene (CFTR)." Biochemical Journal 341, no. 3 (July 26, 1999): 601–11. http://dx.doi.org/10.1042/bj3410601.

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The cystic fibrosis transmembrane conductance regulator gene (CFTR) exhibits a complex pattern of expression that shows temporal and spatial regulation, although the control mechanisms are not fully known. We have mapped DNase-I-hypersensitive sites (DHSs) flanking the CFTR gene with the aim of identifying potential regulatory elements. We previously characterized DHSs at -79.5 and -20.9 kb with respect to the CFTR translational start site and a regulatory element in the first intron of the gene at 185+10 kb. We have now mapped five DHSs lying 3′ to the CFTR gene at 4574+5.4, +6.8, +7.0, +7.4 and +15.6 kb that show some degree of tissue specificity. The DHSs are seen in chromatin extracted from human primary epithelial cells and cell lines; the presence of the +15.6 kb site is tissue-specific in transgenic mice carrying a human CFTR yeast artificial chromosome. Further analysis of the 4574+15.6 kb DHS implicates the involvement of CCAAT-enhancer-binding protein (C/EBP), cAMP-response-element-binding protein (CREB)/activating transcription factor (ATF) and activator protein 1 (AP-1) family transcription factors at this regulatory element.

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8

Silva, Joel Cordeiro da, Arno Bernando Heldwein, Gustavo Trentin, Nereu Augusto Streck, and Fabrina Bolzan Martins. "Funções de distribuição de probabilidade decendial e mensal para a deficiência hídrica no solo." Ciência Rural 38, no. 7 (October 2008): 1893–99. http://dx.doi.org/10.1590/s0103-84782008000700014.

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A determinação das probabilidades de ocorrência de certos níveis de deficiência hídrica do solo (DHS) é fundamental para o planejamento agropecuário e a gestão ambiental. O objetivo deste trabalho foi determinar as funções de distribuição de probabilidades (fdp) que melhor caracterizam a distribuição dos valores de deficiência hídrica no solo. As DHSs decendiais e mensais foram determinadas por meio de balanço hídrico diário do solo para as diferentes capacidades de armazenamento de água disponível dos solos da região de abrangência da estação meteorológica de Santa Maria. Verificou-se que os valores mensais e decendiais de DHS se ajustam às funções de distribuição de probabilidades lognormal, gama, exponencial e Weibull. Utilizando-se as fdp selecionadas para cada período do ano, é possível determinar a probabilidade de ocorrência de qualquer valor de DHS para os solos da região de abrangência da estação meteorológica de Santa Maria.

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9

Chelmenciuc, Corina, and Constantin Borosan. "REGRESSION ANALYSIS OF THE ENERGY PRODUCED IN COGENERATION AND SUPPLIED TO DISTRICT HEATING SYSTEMS." Journal of Engineering Science 28, no. 3 (September 2021): 101–10. http://dx.doi.org/10.52326/jes.utm.2021.28(3).09.

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Currently, the district heating systems (DHSs) are intensively promoted both nationally and globally. The advantages of using these systems in urban areas compared to individual heating systems are practically indisputable. Still, it is essential that the calculation underlying the assessment of the economic profitability of the projects to connect the new heat consumers to DHS be made correctly by taking into account all the necessary investments and the benefits obtained from the additional amount of energy sale. The article presents the methodology for the optimal regression model selection that can be applied to predict the additional electricity produced in cogeneration mode in case of the new heat consumer connection to the DHS, based on the actual data of the thermal and electrical energy supplied to network from a CHP in the Republic of Moldova. At the same time, it is demonstrated that between the thermal energy supplied to a new consumer connected to DHS and the additional electricity produced in the cogeneration mode, there is a direct and linear correlation.

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10

Al Koussa, Jad, Rutger Baeten, Nico Robeyn, and Robbe Salenbien. "A multipurpose test rig for district heating substations: domestic hot water preparation and keep-warm function comparison." E3S Web of Conferences 111 (2019): 06012. http://dx.doi.org/10.1051/e3sconf/201911106012.

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A well performing District Heating Substation (DHS) is crucial for the efficiency of the District Heating (DH), especially with the shift towards low temperature 4th generation DH systems. For this reason, testing and characterization of commercially available DHSs becomes important to estimate their effect on the DH network. Within the thermo-technical laboratory of EnergyVille, a multipurpose test rig has been built for testing DHSs. In this setup, different DH conditions and heat demand profiles for space heating and for Domestic Hot Water (DHW) can be emulated. Independent tests have been performed on 4 DHSs from three different manufacturers, focused on the DHW preparation for low DH supply temperature and on the stand-by/keep-warm operation of the substations. The latter maintains a certain temperature within the heat exchanger to avoid delays in the delivery of DHW. The results showed that improvements are needed on DHW production for lower DH supply temperatures. Also, enhancements are needed to reduce losses from the keep-warm function. Given that DH systems can have thousands of substations, this will reduce the overall losses and improve the performance of the DH network.

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11

Stennikov, V., E. Mednikova, and I. Postnikov. "Determination of an Effective Heating Radius in District Heating Systems in terms of Reliability." Energy Systems Research, no. 1(13) (May 28, 2021): 54–62. http://dx.doi.org/10.38028/esr.2021.01.0007.

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The paper presents a method developed to determine an effective heating radius (EHR) in district heating systems (DHSs) in terms of reliable heat supply to consumers. The search for EHR for various heating mains from the considered district heating source in DHS involves identifying heat source operation zones in various city areas. At the same time, apart from the search for EHR, the nodal reliability indices are estimated for each consumer and then used (if necessary) to adjust the obtained EHR. The paper briefly discusses some of the practical research results.

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12

Corkett, Michael. "The Quality of Canadian and U.S. Government Health Documents Remains Unchallenged Until Better Research Can Be Undertaken." Evidence Based Library and Information Practice 1, no. 4 (December 11, 2006): 74. http://dx.doi.org/10.18438/b8rc71.

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A review of: Lambert, Frank. “Assessing the Authoritativeness of Canadian and American Health Documents: A Comparative Analysis Using Informetric Methodologies.” Government Information Quarterly 22.2 (2005): 277-96. Objective - To assess by means of citation analysis whether the public trust afforded health documents published by the Canadian and U.S. governments is appropriate, and to ascertain whether differences in the respective health care systems influence how publications are produced. Design – Comparative study. Setting – The Canadian Depository Service Program (DSP) and the U.S. Department of Health and Human Services (DHHS) web sites. Subjects – One hundred sixty-six electronic documents sourced from the DSP website, and 284 electronic documents sourced from the DHHS website. Methods – Subjects were randomly selected from repositories offering the most comprehensive collections. Documents with evidence of references to other works used in preparation were separated from those without such characteristics. Data variables were collected from documents with evidence of references. Statistical analysis of the data was undertaken. Main results – Of the respective samples, 89 (53%) from the DSP and 109 (38.4%) from the DHHS contained references. Personal authors were identified in 46 (51.7%) and 63 (58%) of the respective subsets. Handbooks and guidebooks accounted for the largest portion of the DSP subset (29; 32.6%) and government periodicals were the largest constituent of the DHHS subset (41; 37.6%). Scholarly journals were the most common reference type for both the DSP (44%) and the DHHS (58.5%) subsets. The number of references per document was widely dispersed for both subsets; the DSP mean was approximately 64 (SD=114.68) and the DHHS was 73.71 (SD=168.85). Kruskal-Wallis subset analysis of median number of references by document type found differences generalizable to the entire DSP and DHHS populations. Health Canada Reports, handbooks, and guidebooks contained significantly more references than periodical articles or fact sheets. Certain DHSS documents, classified as “other,” contained more references than periodical articles. Canadian documents were more likely to contain references than U.S. documents. Comparison of documents to determine whether one country employs more rigorous citation practices did not produce statistically significant results. U.S. Federal Government documents are more likely to be referenced in other U.S. government health documents, compared to Canadian publications. The presence of references in documents from either country significantly affected likelihood of being cited by web authors. Conclusion – Significant differences in reference use frequencies between DSP and DHHS documents challenges Foskett’s stance that documents of value contain references (Foskett). Use of peer-reviewed scholarly journals for both DSP and DHHS publications was reassuring, suggesting a fairly rigorous publication standard. Reliance of DHHS publications upon federal government documents remains unclear. Referencing of DSP documents, irrespective of reference usage suggests a level of trust towards Canadian government health publications. Web authors appear more comfortable citing referenced DHHS documents. Further study could involve the examination of reference frequency by journal compared against journal impact factors.

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13

Leung, Yue Hei, Sonja Christiane Bäßler, Christian Koch, Theresa Scheu, Ulrich Meyer, Sven Dänicke, Korinna Huber, and Ákos Kenéz. "Sphingolipid Profiling Reveals Different Extent of Ceramide Accumulation in Bovine Retroperitoneal and Subcutaneous Adipose Tissues." Metabolites 10, no. 11 (November 19, 2020): 473. http://dx.doi.org/10.3390/metabo10110473.

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Sphingolipids are bioactive lipids that can modulate insulin sensitivity, cellular differentiation, and apoptosis in a tissue-specific manner. However, their comparative profiles in bovine retroperitoneal (RPAT) and subcutaneous adipose tissue (SCAT) are currently unknown. We aimed to characterize the sphingolipid profiles using a targeted lipidomics approach and to assess whether potentially related sphingolipid pathways are different between SCAT and RPAT. Holstein bulls (n = 6) were slaughtered, and SCAT and RPAT samples were collected for sphingolipid profiling. A total of 70 sphingolipid species were detected and quantified by UPLC-MS/MS in multiple reaction monitoring (MRM) mode, including ceramide (Cer), dihydroceramide (DHCer), sphingomyelin (SM), dihydrosphingomyelin (DHSM), ceramide-1-phosphate (C1P), sphingosine-1-phosphate (S1P), galactosylceramide (GalCer), glucosylceramide (GluCer), lactosylceramide (LacCer), sphinganine (DHSph), and sphingosine (Sph). Our results showed that sphingolipids of the de novo synthesis pathway, such as DHSph, DHCer, and Cer, were more concentrated in RPAT than in SCAT. Sphingolipids of the salvage pathway and the sphingomyelinase pathway, such as Sph, S1P, C1P, glycosphingolipid, and SM, were more concentrated in SCAT. Our results indicate that RPAT had a greater extent of ceramide accumulation, thereby increasing the concentration of further sphingolipid intermediates in the de novo synthesis pathway. This distinctive sphingolipid distribution pattern in RPAT and SCAT can potentially explain the tissue-specific activity in insulin sensitivity, proinflammation, and oxidative stress in RPAT and SCAT.

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14

Kuehn, Bridget M. "DHHS Overhaul." JAMA 301, no. 4 (January 28, 2009): 370. http://dx.doi.org/10.1001/jama.2008.986.

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15

Kulau, Ulf, Juergen Herpel, Ran Qedar, Patrick Rosenthal, Joachim Krieger, Friedrich Schoen, and Ivan Masar. "Towards modular and scalable on-board computer architecture." it - Information Technology 63, no. 4 (July 2, 2021): 185–97. http://dx.doi.org/10.1515/itit-2020-0037.

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Abstract The demand for satellites and space systems with ever-increasing avionics requirements is constantly growing, whether in the field of satellite communications or earth observation. Traditional architectures for Data Handling Systems (DHS) on satellites are reaching their limits in terms of flexibility, interoperability and reusability, while slowing down the innovation cycle due to costly qualification. With regard to commercial and industrial solutions, it is evident that ‘plug and play’-like systems based on open standards can overcome the above-mentioned disadvantages. For this reason, this paper describes how open standards could affect the architecture of future satellite DHSs. In particular it shows an transition path from the traditional federated architecture to a centralized but modular architecture based on adapted industrial standards.

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16

BARRY, CAMILLE T., and LILLIAN K. GIBBONS. "DHHS Nursing Roundtable." Nursing Management (Springhouse) 21, no. 9 (September 1990): 64???70. http://dx.doi.org/10.1097/00006247-199009000-00025.

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17

Tejativaddhana, Phudit, David Briggs, Orapin Singhadej, and Reggie Hinoguin. "Developing primary health care in Thailand." Public Administration and Policy 21, no. 1 (July 2, 2018): 36–49. http://dx.doi.org/10.1108/pap-06-2018-005.

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Purpose The purpose of this paper is to describe progress in an across sectorial approach to primary health care at the district health service (DHS) level in Thailand in response to recent innovative national public policy directions which have been enshrined in constitutional doctrine and publicly endorsed by the Prime Minister. This paper describes one response to the Prime Minister’s challenge for Thailand to become the centre of learning in the sub-region in health management. Design/methodology/approach The authors utilised a descriptive case study approach utilising an analysis of the Naresuan University initiative of establishing the College of Health Systems Management (NUCHSM). Within that case study, there is a focus on challenges relevant to the socio-economic determinants of health (SOED) and an emphasis on utilising Sustainable Development Goals (SDGs) within the DHS structure. Findings The findings describe the establishment of the NUCHSM. A Master of Science (Health Systems Management) by research and a PhD degree have been created and supported by an international faculty. The Thailand International Cooperation Agency recognised NUCHSM by providing scholarships. International students are from Bangladesh, Bhutan, Kenya, Malawi and Timor Leste. Research consultancy projects include two in Lao People’s Democratic Republic; plus, a prototype DHS management system responsive to SDG attainment; and a project to establish a sustainable Ageing Society philosophy for a Thai municipality. Originality/value The case study on NUCHSM and its antecedents in its development have demonstrated originality in a long-standing international collaboration, and it has been recognised by the national government to provide scholarships to citizens of the countries in the sub-region to undertake postgraduate studies in health management. The concept of learning from each other and together, simultaneously as a group, through action research projects funded to enhance the evolution of DHSs is innovative.

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18

Bonnaire, Felix, Ralf Hellmund, and Thomas Lein. "DHS." Trauma und Berufskrankheit 5 (March 1, 2003): s162—s170. http://dx.doi.org/10.1007/s10039-001-0500-z.

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19

HUANG, Weei-Yuarn, and Choong-Chin LIEW. "A conserved GATA motif in a tissue-specific DNase I hypersensitive site of the cardiac α-myosin heavy chain gene." Biochemical Journal 325, no. 1 (July 1, 1997): 47–51. http://dx.doi.org/10.1042/bj3250047.

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Transgenic analysis has indicated that far upstream regulatory elements of the cardiac α-myosin heavy chain (MyHC) gene are required for appropriate transgene expression [Subramaniam, Gulick, Neumann, Knotts and Robbins (1993) J. Biol. Chem. 268, 4331–4336]. In an attempt to identify these as-yet-undefined regulatory elements, we mapped the DNase I hypersensitive sites (DHSs) in the 4 kb upstream region of the hamster cardiac α-MyHC gene. When using nuclei isolated from late-gestational and adult heart ventricles, a strong DHS was identified in the -1.9 kb region (α-1.9 kb site). It cannot be detected in kidney, liver or cardiofibroblast nuclei. Within this site, we found a conserved GATA-motif that interacts specifically with GATA-binding factors in nuclear extracts of cardiomyocytes at various developmental stages. These data provide further evidence to support the role of GATA factors in the regulation of cardiac α-MyHC gene expression.

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20

Warden, J. "Demise of the DHSS." BMJ 296, no. 6632 (May 7, 1988): 1341. http://dx.doi.org/10.1136/bmj.296.6632.1341.

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21

Lewis, John. "Break-up of DHSS." Lancet 332, no. 8605 (July 1988): 290. http://dx.doi.org/10.1016/s0140-6736(88)92593-7.

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22

Foreman, Julie. "DHHS Cataract Guidelines Released." Archives of Ophthalmology 111, no. 5 (May 1, 1993): 591. http://dx.doi.org/10.1001/archopht.1993.01090050025018.

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23

Vastag, B. "Top Advisors Leave DHHS." JAMA: The Journal of the American Medical Association 289, no. 11 (March 19, 2003): 1368—b—1368. http://dx.doi.org/10.1001/jama.289.11.1368-c.

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24

Grant, R. "DHSC is not listening." British Dental Journal 230, no. 2 (January 2021): 60–61. http://dx.doi.org/10.1038/s41415-021-2619-6.

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25

Kim, Hongbi, Hyunseok Shin, Junho Hwang, and Taejin Lee. "Malware Variants Detection based on Dhash." Journal of KIISE 46, no. 11 (November 30, 2019): 1207–14. http://dx.doi.org/10.5626/jok.2019.46.11.1207.

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26

Devi, Swagatika, Sambit Bakshi, and Manmath Narayan Sahoo. "NITR-DHH." ACM SIGBioinformatics Record 9, no. 1 (January 22, 2020): 1. http://dx.doi.org/10.1145/3380874.3380875.

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27

Maisaroh, Maisaroh, Indra Budi Susetyo, and Bayu Rusmandana. "SINTESIS ASAM 9,10-DIHIDROKSI STEARAT (DHSA) MELALUI HIDROLISA EPOKSIDA DARI OKSIDASI ASAM OLEAT DENGAN ASAM PERFORMAT." REAKTOR 16, no. 2 (August 11, 2016): 57. http://dx.doi.org/10.14710/reaktor.16.2.57-64.

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SYNTHESIS OF 9,10-DIHYDROXYSTEARIC ACID (DHSA) THROUGH HYDROLYSIS EPOXIDE FROM OXIDATION OLEIC ACID AND PERFORMIC ACID. 9,10-dihydroxy stearic acid (DHSA); C18H36O4 is one of hydroxyl fatty acids with hydroxyl groups (OH) and carboxyl groups (-COOH) cause DHSA have unique properties for many applications including as an emulsifier in the oil phase/gel candles and water in cosmetic formulations. This study investigated the formation of DHSA of from oleic acid and performic acid through epoxidation and hydrolysis reactions. Epoxidation was carried out by reacting the oleic acid with formic acid to form performic acid in situ reaction at a temperature of 60-70oC with stirring in order to minimize byproduct, followed hydrolysis obtained DHSA as powder with melting point 86.5oC, iodine value 0.125 g I2/100 g, acid value 171.53 mg KOH/g, the hydroxyl group observed at the absorption band region of 3345.34 cm-1, LCMS analysis results show peak spetrograms-mass at m/z 317,269, with a value m/z is equivalent to molecular weight DHSA. Keywords: DHSA; epoxidation; hydrolysis; hydroxyl fatty acids; oleic acid Abstrak Asam 9,10-dihidroksi stearat (DHSA) dengan rumus molekul C18H36O4 merupakan senyawa hidroksil asam lemak dengan gugus hidroksil (-OH) dan karboksil (-COOH) menyebabkan DHSA memiliki sifat unik untuk berbagai aplikasi antara lain sebagai emulsifier antara fasa minyak/lilin gel dan air dalam formulasi kosmetik. Penelitian ini bertujuan untuk menghasilkan DHSA dari asam oleat dan asam performat, melalui tahapan reaksi epoksidasi dan hidrolisa. Epoksidasi asam oleat dengan asam performat yang dibentuk secara in situ dilakukan pada suhu reaksi 60-70oC dengan pengadukan untuk meminimalkan reaksi samping, dilanjutkan dengan hidrolisa epoksida diperoleh DHSA berupa serbuk berwarna putih gading dengan titik leleh 86,5oC, bilangan iod ± 0,125 g I2/100 g, bilangan asam 171,53 mg KOH/g, gugus hidroksil teramati menggunakan FTIR pada bilangan gelombang 3345,34 cm-1, yang diperkuat dengan data kromatogram LC-MS yang memberikan puncak spektrogram-massa pada m/z 317.269, dengan harga m/z yang setara dengan Berat Molekul DHSA. Kata kunci: DHSA; epoksidasi; hidrolisa; hidroksil asam lemak; asam oleat

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McNally, Maura. "Opinion split on DHSS reshuffle." Nursing Standard 2, no. 44 (August 6, 1988): 8. http://dx.doi.org/10.7748/ns.2.44.8.s14.

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Stewart, Gill. "DHSS Policy and Probation Practice." Probation Journal 35, no. 1 (March 1988): 3–5. http://dx.doi.org/10.1177/026455058803500102.

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Bartlett, John G. "DHHS Issues Adult Guideline Revisions." HIV Clinical Trials 5, no. 3 (June 2004): 168–69. http://dx.doi.org/10.1310/dy1h-v073-jqea-uuny.

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COTTON, JOANNA. "The DHSS integrated library system." Health Libraries Review 2, no. 4 (December 1985): 170–76. http://dx.doi.org/10.1046/j.1365-2532.1985.240170.x.

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Shrigley, Sheila M. "Extending access to DHSS publications." Health Libraries Review 6, no. 2 (June 1989): 124–27. http://dx.doi.org/10.1046/j.1365-2532.1989.62010727.x.

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Kuehn, Bridget M. "DHHS Halts Quality Improvement Study." JAMA 299, no. 9 (March 5, 2008): 1005. http://dx.doi.org/10.1001/jama.299.9.1005.

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Hall, M. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 70. http://dx.doi.org/10.1136/bmj.290.6461.70-a.

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Clarke, A. K. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 70. http://dx.doi.org/10.1136/bmj.290.6461.70-b.

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Simmons, R. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 70. http://dx.doi.org/10.1136/bmj.290.6461.70-c.

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Hopkins, R. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 71. http://dx.doi.org/10.1136/bmj.290.6461.71.

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Gosden, C. W. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 71. http://dx.doi.org/10.1136/bmj.290.6461.71-a.

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Ancill, R. J. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 71. http://dx.doi.org/10.1136/bmj.290.6461.71-b.

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Morgan, K. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 71. http://dx.doi.org/10.1136/bmj.290.6461.71-c.

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Grimes, D. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 71. http://dx.doi.org/10.1136/bmj.290.6461.71-d.

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Evans, R. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 71–72. http://dx.doi.org/10.1136/bmj.290.6461.71-e.

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Williams, J. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 72. http://dx.doi.org/10.1136/bmj.290.6461.72.

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Wilson, H. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 72. http://dx.doi.org/10.1136/bmj.290.6461.72-a.

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Horton, G. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 72. http://dx.doi.org/10.1136/bmj.290.6461.72-b.

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McInnes, A. A. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 72. http://dx.doi.org/10.1136/bmj.290.6461.72-c.

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Griffin, J. P. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 72. http://dx.doi.org/10.1136/bmj.290.6461.72-d.

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Wilkinson, S. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 72. http://dx.doi.org/10.1136/bmj.290.6461.72-e.

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Williams, D. L. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 72. http://dx.doi.org/10.1136/bmj.290.6461.72-f.

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Jago, J. P. H. "Doctors, drugs, and the DHSS." BMJ 290, no. 6461 (January 5, 1985): 72–73. http://dx.doi.org/10.1136/bmj.290.6461.72-g.

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