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Dissertations / Theses on the topic 'Detective novels'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

MAGDALENO, RENATA FERNANDES. "CONVICTION ISN T TRUE: DETECTIVE NOVELS AND URBANITY EXPERIENCE." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2007. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=10343@1.

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CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>No fim da década de 90, o mundo assistiu a um boom do romance policial. Na pós-modernidade, com a retomada dos gêneros literários, as narrativas de mistério ganham força e atingem o mercado editorial brasileiro. Mas o policial chega repaginado para o leitor. Não que os elementos da trama dedutiva ou do noir tenham desaparecido nas histórias contemporâneas, mas o formato conhecido e aceito pelo público vem sendo usado para aprofundar questões da sociedade contemporânea. A presente dissertação procura, portanto, mostrar como

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2

Marinkovic, Sladana. "Female detectives in modern detective novels : an analysis of Miss Marple and V. I. Warshawski." Thesis, University West, Department of Social and Behavioural Studies, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-1481.

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3

Routledge, Christopher. "Modernity and identity in the detective novels of Raymond Chandler." Thesis, University of Newcastle Upon Tyne, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388154.

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4

Mullen, Anne W. "Historical and fictional narratives in Sciascia." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297880.

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5

Wood, Meredith Ahner. "Re/sisters in crime : politics and sexuality in lesbian detective novels /." Diss., ON-CAMPUS Access For University of Minnesota, Twin Cities Click on "Connect to Digital Dissertations", 2000. http://www.lib.umn.edu/articles/proquest.phtml.

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6

Reyes, Torres Agustín. "The creation of an Alternative Subjectivity in Walter Mosley's Detective Novels." Doctoral thesis, Universitat de València, 2008. http://hdl.handle.net/10803/9796.

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Walter Mosley reappropriates the detective conventions to represent the American society of the 1950s and 1960s from a marginal perspective. He creates a black private eye, Easy Rawlins, whose profile mirrors that of his white counterparts but also subverts it.This thesis analyzes Raymond Chandler's canonical work "The Simple Art of Murder" and establish those traits that characterize Easy Rawlins. Likewise, it compares Mosley and Chester Himes's black detective heroes and highlight the traits that they have in common. Secondly, focusing on the perspective on identity, consciousness, and subje

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Matthews, Nicole. "The guilty gender : escaping femininity through the detective novels of P.D. James /." Title page, contents and introduction only, 1990. http://web4.library.adelaide.edu.au/theses/09AR/09arm441.pdf.

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8

卓紹雯 and Siu-man Maggie Cheuk. "The construction of gender and morality in crime novels." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31222316.

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Cheuk, Siu-man Maggie. "The construction of gender and morality in crime novels /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22142666.

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10

Sarnelli, Debora Antonietta. "Landscapes of Murder: Exploring Geographies of Crime in the Novels of Agatha Christie." Doctoral thesis, Universita degli studi di Salerno, 2019. http://elea.unisa.it:8080/xmlui/handle/10556/4512.

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2017 - 2018<br>Mystery novels and literary geography have not often intersected. Crime fiction, for instance, has frequently been examined in terms of temporality, rather than in terms of spatiality. Todorov, in this respect, argues that crime narratives, in particular the clue-puzzle forms, are constructed on a temporal duality: the story of the crime – tells what really happened, and the story of the detective’s investigation – the way the detective/narrator presents it to the reader. The two stories eventually converge when the sleuth unmasks the murderer (Todorov 1977). The aim of the res

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11

Lindqvist, Caroline. "Suspect Behaviour : A Gender Perspective on Male and Female Characters in Two Detective Novels by Agatha Christie." Thesis, Linnéuniversitetet, Institutionen för språk (SPR), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-27225.

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This essay is a gender analysis of some of the characters created by Agatha Christie. The aim is to investigate the occurrence of gender stereotypes and if traditional gender norms are challenged by men and/or women characters in Evil Under the Sun and The Body in the Library. Initially, there is an introduction to gender theories which includes the theorists Thomas Laqueur and Simone de Beauvoir among others. Laqueur presents the evolution of gender theories, specifically the two-sex model in which it was believed that sex is pervasive and thus the body rules the mind. Theories presented by h

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12

Martin, Christina R. "A mystery about this : justified sin and very private memoirs in the detective novels of Josephine Tey." Thesis, University of Strathclyde, 2001. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21169.

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This thesis examines the eight detective novels produced between 1929 and 1952 by the Scottish writer best known as Josephine Tey. On this side of the Atlantic they are largely out of print and seem almost forgotten. In America, by contrast, her work has grown in reputation and receives respectful academic attention. Critics there examining the novels point to unusual elements in them which they cannot explain. This thesis considers briefly her work as a playwright, novelist and biographer written in the name of Gordon Daviot. Its central concern however, is to address the problems perceived b

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13

Barfoot, Nicola. "Frauenkrimi : generic expectations and the reception of recent French and German crime novels by women = Polar féminin /." Frankfurt am Main [u.a.] : Lang, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015744779&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA.

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14

Maljukanovic, Bojana. "Dialogues in classical detective novels : an analysis of male and female dialogues in Agatha Christies "Death in the clouds"." Thesis, University West, Department of Social and Behavioural Studies, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-1480.

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15

Malatji, Permission Agosi. "Examining a comparative depiction of crime in Smith and Nesbo's selected novels : an afro-western perspective." Thesis, University of Limpopo, 2019. http://hdl.handle.net/10386/3192.

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Thesis (M. A.(English Studies)) --University of Limpopo, 2019<br>This study explores a literary comparative examination of crime between Africa and Scandinavia, with special attention to Botswana and Norway. Smith’s and Nesbo’s selected novels are used as primary texts for analysis. The novels are, therefore, set in two different areas. These writers depict crime from the African and European perspectives. Chapter One deals with a brief introduction, and the aim and objectives of the study. It also expands on the theoretical background and provides definitions of terms that are used in this

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Monello, Valeria. "A Foreignising or a Domesticating Approach in Translating Dialects? Andrea Camilleri s detective novels in English and The Simpsons in Italian." Doctoral thesis, Università di Catania, 2012. http://hdl.handle.net/10761/1209.

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This doctoral thesis titled A Foreignising or a Domesticating Approach in Translating dialects? Andrea Camilleri s detective novels in English and The Simpsons in Italian is divided into four parts: 1) an introductory chapter dealing with the most noteworthy translation theories developed in the Western World over the centuries, with a special focus on Translation Studies; 2) a second part analysing two detective novels by Andrea Camilleri, in particular those passages that, because of the high concentration of diatopic, diastratic and diaphatic varieties and the combined use of standard and

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Malatjie, Permission Agosi. "Examining a comparative depiction of crime in Smith and Nesbo's selected novels : an afro-western perspective." Thesis, University of Limpopo, 2019. http://hdl.handle.net/10386/3059.

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Thesis (M. A.) --University of Limpopo, 2019.<br>This study explores a literary comparative examination of crime between Africa and Scandinavia, with special attention to Botswana and Norway. Smith’s and Nesbo’s selected novels are used as primary texts for analysis. The novels are, therefore, set in two different areas. These writers depict crime from the African and European perspectives. Chapter One deals with a brief introduction, and the aim and objectives of the study. It also expands on the theoretical background and provides definitions of terms that are used in this paper. Chapter

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18

Leavitt, Joshua. "By the Book: American Novels about the Police, 1880-1905." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1598175125397595.

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19

Cannon, Ammie. "Controversial Politics, Conservative Genre: Rex Stout's Archie-Wolfe Duo and Detective Fiction's Conventional Form." BYU ScholarsArchive, 2006. https://scholarsarchive.byu.edu/etd/469.

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Rex Stout maintained his popular readership despite the often controversial and radical political content expressed in his detective fiction. His political ideals often made him many enemies. Stances such as his ardent opposition to censorship, racism, Nazism, Germany, Fascism, Communism, McCarthyism, and the unfettered FBI were potentially offensive to colleagues and readers from various political backgrounds. Yet Stout attempted to present radical messages via the content of his detective fiction with subtlety. As a literary traditionalist, he resisted using his fiction as a platform for an

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20

Pereira, Edson Salviano Nery. "Fantasmas que investigam: nação, masculinidades, violência em A Varanda do Frangipani e O Filho da Mãe." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/8/8156/tde-06082018-182711/.

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Esta dissertação apresenta um estudo comparativo tendo como objetos de investigação os romances A varanda do frangipani (2007), de Mia Couto, e O filho da mãe (2009), de Bernardo Carvalho. Considerando que os dois romances se apresentam como narrativas ligadas ao gênero literário romance policial, buscou-se analisar de que maneiras tais romances apresentam modalizações e reformulações em relação aos aspectos formais e estruturais deste gênero. A partir destas constatações, a investigação debruça-se sobre os conflitos gerados pelas relações de gênero, enfatizando os encontrados na elaboração da

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21

Engar, Amy Kimball. "Mystery writers in foreign settings : the literary devices and methods used to portray foreign geographies /." Diss., CLICK HERE for online access, 2005. http://contentdm.lib.byu.edu/ETD/image/etd727.pdf.

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22

Löwe, Corina. "Von Jungen Pionieren und Gangstern : Der Kinder- und Jugendkriminalroman in der DDR." Doctoral thesis, Stockholms universitet, Institutionen för baltiska språk, finska och tyska, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-60269.

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This dissertation examines detective novels for children and young adults written and published in the German Democratic Republic (GDR). The aim of the thesis is to study how the genre developed under the conditions of a socialist society. The analysis of the 66 texts included in the corpus is based on a socio-historical approach assuming that dialogical interdependencies between texts and society exist and can be verified. Central to the analytical work with the texts is the thesis that detective novels written for young readers reflect the socio-political development in East-German society.

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23

Aviles, Arenas Leonor. "Des images et des imaginaires de la corruption dans les romans et les films Perder es cuestión de método (1997/2004) de Santiago Gamboa / Sergio Cabrera, Satanás (2002/2007) de Mario Mendoza / Andi Baiz et Paraíso Travel (2001/2008) de Jorge Franco / Simon Brand." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0534.

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La corruption est l’un des problèmes les plus dévastateurs de la Colombie, car elle touche la dimension sociale, politique et éthique. Ce problème est représenté par des pratiques symboliques qui remettent en question la nature de la culture colombienne et son changement. Le roman policier est l’une de ces formes de représentation. Mais l'histoire verbale est recréée, adaptée ou réécrite par des films colombiens qui récupèrent les images et imaginaires déjà présents dans le texte verbal sur le fond de l’univers culturel. Dans cet ordre d’idées, la question qui a guidé la recherche est : quels

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24

Gillis, S. J. "Detecting fictions : resistance and resolution in the golden age detective novel." Thesis, University of Exeter, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341176.

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25

Schultz, Bryan J. "The portrayal of Switzerland and the role of the Swiss detective in the modern Swiss crime novel /." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=79977.

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The primary objective of this M.A. thesis is to examine the portrayal of Switzerland and the role of the Swiss detective in the modern Swiss crime novel, with special focus on the works of three modern Swiss authors of different social status: Friedrich Glauser, Friedrich Durrenmatt and Hansjorg Schneider. While the crime novel is generally considered trivial entertainment for mass audiences within the realm of German literature, the case is somewhat different in Switzerland, a country with a small state mentality. The forthcoming analysis will demonstrate how these authors employ the c

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Vigueras, Fernández Ricardo. "La novela policiaca de temática romana clásica. Rigor e invención." Doctoral thesis, Universidad de Murcia, 2005. http://hdl.handle.net/10803/10804.

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La presente tesis doctoral abarca el estudio de quince obras: siete novelas y un libro de relatos del narrador norteamericano Steven Saylor, cinco novelas del también norteamericano John Maddox Roberts y, finalmente, dos novelas del español Joaquín Borrell. La investigación ha sido llevada a cabo partiendo de las fuentes clásicas para realizar un comentario literario y humanístico de estas obras y ubicarlas dentro del contexto de la moderna novela histórica. Los principales temas de estudio, analizados en capítulos monográficos, han sido: La ciudad de Roma; Policía, guardias y detectives; Mito

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Vargas, Vergara Mabel. "La escritura como táctica abismada de lo policial en Los detectives salvajes de Roberto Bolaño." Tesis, Universidad de Chile, 2004. http://www.repositorio.uchile.cl/handle/2250/110140.

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Informe de Seminario para optar al grado de Licenciado en Lengua y Literatura Hispánica mención Literatura.<br>Informe de Seminario para optar al grado de Licenciado en Lengua y Literatura Hispánica.<br>El objeto de este informe es, en un primer acercamiento, dar cuenta de cómo ciertas prácticas escriturales, generadas en América del norte primero y en América Latina de los años setenta después, contaminan y cuestionan el proyecto moderno sustentado primeramente en la razón y fundamentalmente en la utopía. En el caso de América Latina revisaré, concretamente, la novela Los detectives salvajes

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28

Lake, Darlene Margaret. "The detective as social critic : the Spanish and Mexican detective novel 1970-1995 /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/8312.

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Effron, Malcah. "If only this were a detective novel : self-referentiality as metafictionality in detective fiction." Thesis, University of Newcastle Upon Tyne, 2010. http://hdl.handle.net/10443/838.

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This thesis constitutes the first attempt to examine formally the use of self-referential forms in the detective genre. By focusing detective fiction’s self-referential invocation of the genre within its narratives, it explores the relation between generic boundaries and the boundaries between reality and fictionality. Because the self-referential moments in detective fiction maintain the realistic representation of the narrative frame, they unselfconsciously indicate the textuality of the detective form, so they never wholly expose the disjuncture associated with metafiction. This creates an

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Uribe, Armijo Felipe. "Los detectives salvajes como novela de aventuras." Tesis, Universidad de Chile, 2007. http://repositorio.uchile.cl/handle/2250/110451.

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31

Cecchini, Michael Peter. "Novel detection strategies using SERS." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/11165.

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The use of surface-enhanced Raman spectroscopy (SERS) as an analytical tool has gained increased interest in recent years due to its greater sensitivity and “fingerprinting” ability when compared to other spectroscopic techniques. This thesis discusses approaches used to detect aggregated and single metallic nanoparticles in a high throughput fashion using SERRS. This was accomplished by building a sensitive optical detection platform with high temporal resolution detectors. Initially, nanoparticle aggregates compartmentalized within microdroplets were detected. Each microdroplet can be consid

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Zhao, Weihong. "A Novel Animal Detection Technique for Intelligent Vehicles." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/38045.

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The animal-vehicle collision has been a topic of concern for years, especially in North America. To mitigate the problem, this thesis focuses on animal detection based on the onboard camera for intelligent vehicles. In the domain of image classification and object detection, the methods of shape matching and local feature crafting have reached the technical plateau for decades. The development of Convolutional Neural Network (CNN) brings a new breakthrough. The evolution of CNN architectures has dramatically improved the performance of image classification. Effective frameworks on object dete

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Guardiola, Salmerón Consuelo. "Novel silicon sensors for neutron detection." Doctoral thesis, Universitat Autònoma de Barcelona, 2012. http://hdl.handle.net/10803/117536.

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La detección precisa y la dosimetría de neutrones en campos de radiación mixtos y pulsados es un tema instrumental demandado con gran interés por las comunidades médica e industrial. Estudios recientes de la contaminación de neutrones alrededor de los aceleradores lineales médicos han aumentado la preocupación sobre el riesgo de cáncer secundario en pacientes sometidos a tratamiento de radioterapia en las modalidades de fotones con energías superiores a 8 MeV. En respuesta a esa necesidad, en esta tesis se ha desarrollado una innovadora alternativa a los detectores estándares con un método act

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Fagiolo, Gianlorenzo. "Novel NMR spin selection and detection." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435448.

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35

Bourin, Stephanie. "Novel strategies for DNA detection assay." Thesis, University of London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265939.

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36

Maw, Khin Lay. "Development of a Novel DNA Microchip for Pathogen Detection." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/chemistry_theses/34.

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Although DNA microarray can detect multiple DNA samples simultaneously, current detection techniques involve PCR and other traditional procedures. In this study, a sensitive, specific and rapid detection method, which eliminates PCR and other lengthy processes, for pathogenic DNA is presented. This technology is based on the hybridization of target DNA to the immobilized probe, extension of probe DNAs using the target-DNA as a template and signal generation by streptavidin-horseradish peroxidase and substrate. This method is highly specific and sensitive, allowing single-nucleotide-base mismat

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37

Beasley, Carolyn. "The fingerprint thief a crime novel and exegesis /." Swinburne Research Bank, 2009. http://hdl.handle.net/1959.3/66861.

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Thesis (PhD) - [Higher Education Division - Lilydale], Swinburne Institute of Technology, 2009.<br>Submitted for the degree of Doctor of Philosophy, [Higher Education Division - Lilydale], Swinburne University of Technology, 2009. Includes bibliographical references (p. 351-371)

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38

Huang, Chengqiang. "Featured anomaly detection methods and applications." Thesis, University of Exeter, 2018. http://hdl.handle.net/10871/34351.

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Anomaly detection is a fundamental research topic that has been widely investigated. From critical industrial systems, e.g., network intrusion detection systems, to people’s daily activities, e.g., mobile fraud detection, anomaly detection has become the very first vital resort to protect and secure public and personal properties. Although anomaly detection methods have been under consistent development over the years, the explosive growth of data volume and the continued dramatic variation of data patterns pose great challenges on the anomaly detection systems and are fuelling the great deman

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Mongkolnavin, Rattachat. "CVD polycrystalline diamond a novel neutron detector and applications /." Thesis, Online version, 1998. http://ethos.bl.uk/OrderDetails.do?did=1&uin=uk.bl.ethos.481509.

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40

Richardson, James Alistair. "Novel DNA probes for sensitive DNA detection." Thesis, University of Southampton, 2010. https://eprints.soton.ac.uk/173981/.

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The ability to detect and interrogate DNA sequences allows further understanding and diagnosis of genetic disease. The ability to perform such analysis of genetic material requires highly selective and reliable technologies. Furthermore techniques which can use simple and cheap equipment allow the use of such technologies for point of care analysis. Described in this thesis are two novel DNA probe systems designed for mutation discrimination and sequence recognition of PCR products. A homogenous PCR system using HyBeacons® which utilise FRET to produce a three probe multiplex system and surfac

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Yamazaki, Miki. "Novel technologies for high sensitivity analyte detection." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9999.

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Microfluidic devices are attracting interest for point-of-care diagnostics due to their low unit cost, low reagent and sample usage, fast analysis times and portability. Fluorescence is the most widely used detection method in microfluidics due to its high sensitivity, excellent dynamic range, ease of implementation and non-invasive nature. Fluorescence detection has accordingly been widely used for the interrogation of microfluidic devices, with the majority of reports to date having used non-integrated laser excitation sources coupled with off-chip optics and photodetectors. For point-of-car

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Alakhras, Maram Mustafa. "Breast tomosynthesis: Novel detection of breast cancer." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/14222.

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Purpose: To evaluate the impact of adding digital breast tomosynthesis (DBT) to digital mammography (DM) on radiologists’ performance, confidence and identification of lesions. Also, to evaluate the radiation dose from DBT and DM and to assess image quality at different dose levels. Methods: Twenty six radiologists examined 50 cases in two modes, DM and DM+DBT. The radiologists were classified into three groups as having no DBT experience, workshop DBT and clinical DBT. Radiologists were asked to localize breast lesions, report their type and give a score of 1-5. The first study examined radio

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Nawaz, Muhammad. "Foreground detection of video through the integration of novel multiple detection algorithims." Thesis, Brunel University, 2013. http://bura.brunel.ac.uk/handle/2438/7766.

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The main outcomes of this research are the design of a foreground detection algorithm, which is more accurate and less time consuming than existing algorithms. By the term accuracy we mean an exact mask (which satisfies the respective ground truth value) of the foreground object(s). Motion detection being the prior component of foreground detection process can be achieved via pixel based and block based methods, both of which have their own merits and disadvantages. Pixel based methods are efficient in terms of accuracy but a time consuming process, so cannot be recommended for real time appli

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Rojas, González María Margarita. "El sujeto y el poder en Los detectives salvajes." Tesis, Universidad de Chile, 2007. http://www.repositorio.uchile.cl/handle/2250/110495.

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La novela Los detectives salvajes, publicada en noviembre del año 1998 es la obra de Roberto Bolaño sobre la que centraremos la investigación del presente informe. En este estudio se pretende leer esta novela desde los conceptos de “sujeto” y de “mediatización” a partir del análisis del tipo de sujeto que se configura en la obra de Bolaño y las relaciones de éste con el “poder” en la sociedad posmoderna. Nos situamos ante la obra de Bolaño como si ésta fuera un espejo contradictorio en el que nos vemos reflejados por personajes tan fascinantes en su caracterización que sólo reconoceríamos c

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Page, Leanne Nicole. "Masochistic pleasures of detection in the sensation novels of Wilkie Collins." Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/7233.

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This study analyzes and accounts for the mixed emotional responses to three Wilkie Collins novels: The Dead Secret (1857), The Woman in White (1860), and The Law and the Lady (1875). Contemporary reviews of these novels, in addition to Collins’s comments on the reception of his works, suggest that these novels elicited both positive and negative emotions in readers who took a “masochistic” pleasure in reading frustrating and often terrifying texts. In the role of detective, Collins’s reader is placed in the uncomfortable and untenable position of disciplinarian (ferreting out secrets and res

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Tang, Zongzhi. "A Novel Road Marking Detection and Recognition Technique Using a Camera-based Advanced Driver Assistance System." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/35729.

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Advanced Driver Assistance System (ADAS) was widely learned nowadays. As crucial parts of ADAS, lane markings detection, as well as other objects detection, have become more popular than before. However, most methods implemented in such areas cannot perfectly balance the performance of accuracy versus efficiency, and the mainstream methods (e.g. Machine Learning) suffer from several limitations which can hardly break the wall between partial autonomous and fully autonomous driving.

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Bornefalk, Hans. "Computer-aided detection and novel mammography imaging techniques." Doctoral thesis, Stockholm, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3861.

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48

Karlsson, Filip. "Unfolding probes : A novel method for biomolecular detection." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-198831.

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Unfolding probes is a novel detection method for biomolecules, involving an oligonucleotide probe that can be amplified and which thereby gives rise to a strong signal for individual probe - target interactions. The present project focuses on a variant of unfolding probes called 2-fold probes and on optimizing the detection efficiency of synthetic targets. Furthermore, proof of concept experiments were performed for the detection of Her2 mRNA in cells.

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Li, Gerald. "Novel biomarkers for early cancer detection and screening." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43732.

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Early detection and screening have reduced mortality from many cancers, but there remains a need for improved biomarkers of risk. Cytometric DNA ploidy analysis has been used for the detection, treatment, and management of many cancers, but greater clinical utility would come with increased accuracy. Improvements to ploidy-based screening might come from adding complementary biological information. The first aim combined ploidy with the additional biological information provided by malignancy associated changes as detected by automated nuclear morphometry. In 2249 sputum samples, the resultant

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Prasertsilpa, Varipin. "Studies into novel methods for detection of aflatoxins." Thesis, University of Strathclyde, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249908.

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