Dissertations / Theses on the topic 'Design principles'
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Johansson, Jan. "Cavern wall design principles." Licentiate thesis, KTH, Civil and Architectural Engineering, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-1631.
Full textThis licentiate thesis deals with the design of lined rockcaverns used for the storage of gas under high pressures (20-25MPa). This storage technique has been developed in Swedenduring the last 20 years. The concept has been named LRC (LinedRock Cavern).
The goal of the research has been to develop a methodologyfor the design of the cavern wall so that it can fulfil thesafety demands put placed upon it by the society. To achievethis, an extensive knowledge about the properties of the wallmaterials, and how they interact, is required.
The proposed design methodology is based on the cavern wallbuild-up principles that have emerged during the many years ofdevelopment of the LRC concept. The cavern wall consists, inshort, of (from inside outwards): a gastight steel lining, asliding layer of bitumen, a reinforced concrete lining, ashotcrete layer and finally the rock mass.
In the thesis, a step-by-step approach is proposed toanalyse the deformations and strains that the cavern wall issubjected to as the rock caverns expands as a result of thepressurisation. The analysis begins with an assessment of thedeformation properties of the rock mass and proceeds with anestimation of the deformation in the most strained part of therock cavern. The analysis continues with an examination of howthe rock deformation is transmitted through the wall structure,ending in an assessment of the strain in the most strained partof the steel lining. The final step in the methodology is tocompare the calculated steel strain with the acceptable strain,derived from acceptable risk criteria or extracted fromrelevant codes. As an LRC storage is subjected to hundreds ofload cycles (with potentially high strain levels in the steellining) during its lifetime, the dimensioning load case is lowcycle fatigue.
The methodology is based on several assumptions regardingthe properties of the structural parts included in the cavernwall and how they react to the pressure load, both as singleparts and in interaction with adjacent structural parts. Theassumptions regard e.g. the deformation properties of the rockmass, the behaviour of the rock mass during repeatedhigh-pressure loading, the crack distributing effect of thereinforcement and the properties of the sliding layer.
Support for these assumptions has been gathered fromtheories, previous experiences and performed practical tests.The long concept development work has included numeroustechnical studies and tests, which have been used in thecreation of the design methodology. The experiences gained fromthe Pilot tests in Grängesberg have been especiallyvaluable to this end. A series of laboratory tests on themechanical properties of the sliding layer, for the load casein question, have been performed as part of this licentiatework.
The proposed design methodology for the cavern wall is basedon a probabilistic approach. This approach has been chosen forseveral reasons, among others because LRC is a new technologywithout established design practice and because a probabilisticview is a good way to manage the uncertainties, which in thepresent case originates from the stochastic nature of the rockmass. The properties of the rock mass vary within the volumeand are better described by an interval or a distributioninstead of a deterministic value.
The calculation tools used are in themselves rather simple.The basis is an elastoplastic analytical solution for thedeformation of the rock cavern during pressurisation. Thecalculations are performed as Monte Carlo simulations in aspreadsheet model. The choice of calculation tool was done fortwo main reasons, partly to get a lucid method where each stepin the process can be followed, partly because of limitationsin time and budget. However, a large number of FEM calculationshave been used, in addition to the observed behaviour of thePilot Plant, to verify and calibrate the model.
The proposed methodology shows one practicable way ofdesigning an LRC storage. The methodology has already beenapplied in the design of the worlds first large scale LRCstorage (the LRC Demo Plant at Skallen, near Halmstad insouth-western Sweden).
Areas where it is judged possible to improve or supplementthe proposed design methodology are:A thorough evaluation of the deformationbehaviour of the Demo Plant can be used to check the validityof the assumptions made. Depending on the outcome of such acheck, this might lead to a modification of the designmethodology.The sliding layer is of great importance for thestress and strain in the steel lining. It is urgent to continuethe development and testing of the sliding layer material andits properties.It should be examined if, and in which case how,the use of stochastic FEM analysis, asa calculation tool,could improve the handling of uncertainties in the designmethodology.
Bullock, James N. "Design Principles for Emotional Durability." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1342103850.
Full textVeiga, Maria Inês Costa da. "Indiscipline social design principles and practices." Doctoral thesis, Universidade de Lisboa, Faculdade de Arquitetura, 2020. http://hdl.handle.net/10400.5/20260.
Full textABSTRACT: This thesis is an exploratory study of moves and movements of the design discipline towards social and activist critical practices. It departs from a growing concern for design as a socially committed activity that has been around since the 1960s. The social turn, as we describe it, was a historical plea for designers to expand the nature and complexity of the problems addressed by design, moreover, to involve the users and stakeholders in designing processes. Turning to work with different sectors and diverse publics, the ‘social design’ movement emerged in opposition to the industrial and the commercial paradigms. As participatory and co-design approaches spread to general practice and for all kinds of purposes, social design became increasingly seen as a culture to represent a wider historical actualisation of the discipline. Still, in recent years, authors point to the difficulties of becoming socially engaged. Although literature on the ‘how of’ collaboration abounds i.e. the motivations, structure and techniques to involve others in design processes; it appears co-design entails ambiguous practices where designers often find themselves without a discipline. Struggles to craft a role for design in initiatives coordinated by networks of communities and institutions too often has led to actions imported from other fields hence the end of design. Coming from a background in graphic design, taking steps to become a social designer, we experienced how difficult it is to do away with the discipline. Specific gestures, actions and products in our social engagements that destabilized the visual communication design process also revealed visual communication design practiced in unknown or unexpected ways. Shifting the perspective to consider, beyond destabilization, it is indiscipline that happens to design in the encounter with others we articulated the question: what if choosing to become social is not to lose the discipline? This matter is worth to research because while social design became known for its risky participatory moves, some authors point to shifts in the politics of designing that have not yet been clarified. Through a mixed methodology based on action research and grounded theory we devised case studies to better describe, explain and explore, from a performative perspective and deeper anthropological stance, all that happens in co-design beyond exclusive attention to the design expert. While disclosing different social form-acts of social interaction within design, four images of indiscipline emerged. 1) IT’S ABOUT THE HOW, 2) DESIGN IS THE SITUATION, 3) BEGININGS NOT ENDS, and 4) DESIGN IS A LIVING THING, all point to different sides of the performative and politics turn that happens to design when it becomes social. Addressing the lack of discourse that does not treat the social as a irreducible complexity, this thesis develops a theory of design that reclaims the encounter with others as the space and possibility to grow the discipline in ways that even unexpected may also be radically social. The main conclusion is that indiscipline is not anti-design but an expansion of design possibilities in the encounter with others, which not yet seen or made visible can potentially represent moves from conventional practices towards critical socially engaged designing. Recommendations for future research are to expand the inventive and pedagogic potentials of indiscipline as a concept to understand the social turn and to practice becoming socially engaged in ways that are deemed better for others and ourselves. Another opening is to understand how indiscipline may be articulated in design education how and when students may be ready for design practice to become a more living thing.
This thesis is an exploratory study of moves and movements of the design discipline towards social and activist critical practices. It departs from a growing concern for design as a socially committed activity that has been around since the 1960s. The social turn, as we describe it, was a historical plea for designers to expand the nature and complexity of the problems addressed by design, moreover, to involve the users and stakeholders in designing processes. Turning to work with different sectors and diverse publics, the ‘social design’ movement emerged in opposition to the industrial and the commercial paradigms. As participatory and co-design approaches spread to general practice and for all kinds of purposes, social design became increasingly seen as a culture to represent a wider historical actualisation of the discipline. Still, in recent years, authors point to the difficulties of becoming socially engaged. Although literature on the ‘how of’ collaboration abounds i.e. the motivations, structure and techniques to involve others in design processes; it appears co-design entails ambiguous practices where designers often find themselves without a discipline. Struggles to craft a role for design in initiatives coordinated by networks of communities and institutions too often has led to actions imported from other fields hence the end of design. Coming from a background in graphic design, taking steps to become a social designer, we experienced how difficult it is to do away with the discipline. Specific gestures, actions and products in our social engagements that destabilized the visual communication design process also revealed visual communication design practiced in unknown or unexpected ways. Shifting the perspective to consider, beyond destabilization, it is indiscipline that happens to design in the encounter with others we articulated the question: what if choosing to become social is not to lose the discipline? This matter is worth to research because while social design became known for its risky participatory moves, some authors point to shifts in the politics of designing that have not yet been clarified. Through a mixed methodology based on action research and grounded theory we devised case studies to better describe, explain and explore, from a performative perspective and deeper anthropological stance, all that happens in co-design beyond exclusive attention to the design expert. While disclosing different social form-acts of social interaction within design, four images of indiscipline emerged. 1) IT’S ABOUT THE HOW, 2) DESIGN IS THE SITUATION, 3) BEGININGS NOT ENDS, and 4) DESIGN IS A LIVING THING, all point to different sides of the performative and politics turn that happens to design when it becomes social. Addressing the lack of discourse that does not treat the social as a irreducible complexity, this thesis develops a theory of design that reclaims the encounter with others as the space and possibility to grow the discipline in ways that even unexpected may also be radically social. The main conclusion is that indiscipline is not anti-design but an expansion of design possibilities in the encounter with others, which not yet seen or made visible can potentially represent moves from conventional practices towards critical socially engaged designing. Recommendations for future research are to expand the inventive and pedagogic potentials of indiscipline as a concept to understand the social turn and to practice becoming socially engaged in ways that are deemed better for others and ourselves. Another opening is to understand how indiscipline may be articulated in design education how and when students may be ready for design practice to become a more living thing.
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Jürjens, Jan. "Principles for secure system design." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400047.
Full textHashemi, Nezhad Ashrafi S. "Ethical principles for hospital design." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3022732/.
Full textBamberg, Eberhard 1966. "Principles of rapid machine design." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/88839.
Full textBraman, Suzanne M. "Design principles for transitional housing." College Park, Md.: University of Maryland, 2007. http://hdl.handle.net/1903/7836.
Full textThesis research directed by: School of Architecture, Planning and Preservation Architecture. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
Lu, Karyn Y. "Interaction Design Principles for Interactive Television." Thesis, Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/6962.
Full textBetschon, Felix. "Design principles of integrated magnetic bearings /." Zürich, 2000. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13643.
Full textPettersson, Elena, and Tiffany Thai. "Design Principles in Mobile Web Usability." Thesis, Högskolan i Borås, Akademin för bibliotek, information, pedagogik och IT, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-13387.
Full textAnvändningen av mobila enheter har på senare tid ökat och användningen av bärbara datorer och stationära datorer har minskat. Det blir därför allt viktigare att designa mer användarvänliga hemsidor på olika plattformar. Etablerade design principer för webbdesign anger riktlinjer för design och test av webbanvändbarhet. Design principer används inte i en större utsträckning för att utvärdera användbarheten på mobila hemsidor, därför syftar denna studie till att undersöka hur användbarheten för mobilhemsidor påverkas utifrån att tillämpningen av design principer för webbdesign. Studien bygger på ett analytiskt ramverk där nyckelord har valts ut från ett antal etablerade webbdesign principer. Studien har ett kvalitativt tillvägagångssätt, med experimentella inslag. Studien har genomförts genom heuristik utvärdering, användbarhets studier och eye-tracking experiment. Studien indikerar att det finns en koppling mellan lägre nivåer av tillämpning av webbdesign principer och användbarheten på mobil- och datorsanpassade hemsidor. Denna studie bidrar till en djupare förståelse om hur anpassningen av design principer och dess påverkan av användbarheten på hemsidor över olika plattformar.
Neishabouri, Mohammad Ali. "Engineering design principles of neural fibres." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/41037.
Full textCockburn, Andrew Jeremy Gavin. "Groupware design : principles, prototypes, and systems." Thesis, University of Stirling, 1993. http://hdl.handle.net/1893/21581.
Full textKorniienko, A. O. "The Main Principles of Interior Design." Thesis, Київський національний університет технологій та дизайну, 2017. https://er.knutd.edu.ua/handle/123456789/8391.
Full textKoh, YunJu Lee. "Healing Interior: Using Eastern Design Principles in Hotel Design." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd/1198.
Full textChai, Wanqi M. D. "Porcelain Color Guide and Application Principles." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1337289222.
Full textTyler, Kenneth Ronald Jr. "Impressionism as architecture : an investigation of design principles." Thesis, Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/24132.
Full textLim, Brian Yoo-Jin. "Principles for architecting complex systems." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/9902.
Full textInal, Yavuz. "Physically Interactive Educational Game Design For Children: Defining Design Principles." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613972/index.pdf.
Full textDevelopment Research Model was administered under the Design-Based Research. Both Mathematics and Physical Education subjects were integrated within the game environments. Totally four physically interactive games were designed and developed. During the design and development phases, field experts, subject-matter experts and children&rsquo
s expectations, needs and recommendations were taken into account. During the development phase, 5 teachers with 3 Mathematics and 2 Physical Education teachers as subject matter experts participated to the study. Also, 10 v children with 5 boys and 5 girls participated to the design phase. In the implementation phase, 30 children with 17 boys and 13 girls participated in Pilot Implementation and 50 children with 27 boys and 23 girls participated to the Final Implementation phase. The study revealed that camera screen was the main deterministic factor in order to play physically interactive educational games properly. Girls and boys had different considerations about the developed games. The bigger camera screen physically interactive games had, the higher motivation children had during gameplay. At the end of the study, design principles of physically interactive educational games were defined.
Pesavento, Luca. "Evaluating Situation Awareness Oriented Design Principles as a Design Tool." Thesis, KTH, Skolan för datavetenskap och kommunikation (CSC), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-169634.
Full textI kritiska situationer, såsom kraftverkshantering eller flyplansledning, kan mänskliga fel ha allvarliga konsekvenser. Det är därför viktigt att tekniska operatörer har en god uppfattning av den aktuella situationen. En nyckelfråga då interaktiva system för dessa användare designas är därför att tillhandahålla en hög situationsmedvetenhet, där många faktorer beaktas för att undvika farliga situationer. Situation Awareness Oriented Design (SAOD) är en metodik som använder designprinciper som vägledning då system anpassas för att tillhandahålla god situationsmedvetenhet. I denna studie undersöks vilka problem som uppstår när man använder ett urval av SAOD-principer som det främsta verktyget i designprocessen. Forskningen genomfördes med hjälp av en designmetodik där SAOD-principer användes för att utforma D4SH, ett interaktivt översiktsystem för servicecenter inom den marina sektorn. Studiens resultat indikerar fyra problem som kan uppstå genom att använda dessa principer i en designprocess. Först och främst upplevdes principerna inte underlätta designbeslut. För det andra var principerna indirekt motsägelsefulla då ett beslut skulle fattas. För det tredje behövdes en grundläggande användaranalys för att använda principerna korrekt. För det fjärde belyste principerna i vissa lägen problem utan att erbjuda en önskvärd lösning. Baserat på detta ifrågasätts principernas giltighet och konsekvenser av att använda principerna som ett kompletterande designverktyg föreslås. Slutsatsen av studien hävdar att problemen som identifieras är en nödvändig kompromiss för att kunna erbjuda en kraftfull ram, som framgångsrikt kan användas i många sammanhang för att tillhandahålla situationsmedvetenhet.
Harrison, Anna. "Principles of experience design for airport terminals." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/83947/1/Anna_Harrison_Thesis.pdf.
Full textMawle, Richard G. "Integration of EcoDesign principles within small product design consultancies." Thesis, Loughborough University, 2018. https://dspace.lboro.ac.uk/2134/33186.
Full textVELLORE-KANDABABU, MANOJ BABU, and GANAPATHY VARMA INDUKURI SANTOSH. "ANALYSIS ON WEBSITE DESIGN USING USABILITY PRINCIPLES." Thesis, Högskolan i Borås, Institutionen Handels- och IT-högskolan, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-20448.
Full textCarvajal, Angel J. "First principles design of coreless power transformers." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/120875.
Full textThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 117-118).
This thesis presents a theoretical foundation and methodology for designing novel 4-coil high frequency coreless power transformers from first principles via lumped equivalent circuit models. The procedure is applied to construct a design for 100W transformer with an S21 parameter value of .96. Using MATLAB and LTspice, simulation tools have been developed to produce accurate predictions of inductance, resistance, coupling coefficients, and S21 parameter values for an ensemble of coil models. These theoretical calculations have been employed for spiral and cylindrical coils and have been validated with numerous constructed experimental designs. The utility uses a first principles approach and derives these calculations directly from the physical parameters and relative positions of the coils. Simulation outputs greatly aid the engineering task of designing an efficient coreless power transformer.
by Angel J. Carvajal.
M. Eng.
Montgomery, Sean J. (Sean Joseph) 1979. "Competitive physics : teaching fundamental principles through design." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/89928.
Full textPlostinar, Ciprian. "Design principles for high power linear accelerators." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:c425c3c8-772c-49a0-8764-257ae6af5bd6.
Full textДядечко, Алла Миколаївна, Алла Николаевна Дядечко, Alla Mykolaivna Diadechko, and E. I. Nagornyy. "The key principles of effective questionnaire design." Thesis, Видавництво СумДУ, 2008. http://essuir.sumdu.edu.ua/handle/123456789/16075.
Full textLindqvist, Zebh. "Design Principles for Visual Object Recognition Systems." Thesis, Luleå tekniska universitet, Institutionen för system- och rymdteknik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-80769.
Full textMoore, Freeman Leroy. "Quantifying Design Principles in Reusable Software Components." Thesis, University of North Texas, 1995. https://digital.library.unt.edu/ark:/67531/metadc278795/.
Full textFeng, Song. "Exploring design principles of cellular information processing." Thesis, University of Warwick, 2015. http://wrap.warwick.ac.uk/79687/.
Full textParrish, Bradley D. "Sustainability entrepreneurship : design principles, processes, and paradigms." Thesis, University of Leeds, 2007. http://etheses.whiterose.ac.uk/347/.
Full textMustafa, Mudassir Imran. "Design Principles for Data Export : Action Design Research in U-CARE." Thesis, Uppsala universitet, Institutionen för informatik och media, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-180061.
Full textSohaib, Amir Khan Muhammad, and Tariq Ashraf. "Tentative Interaction Design Principles for the Design of Online Booking Systems." Thesis, Högskolan i Borås, Institutionen Handels- och IT-högskolan, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-20382.
Full textProgram: Magisterutbildning i informatik
Fox, Stephen John. "Application of design for manufacture principles to building design and construction." Thesis, Sheffield Hallam University, 2001. http://shura.shu.ac.uk/19207/.
Full textGonzalez, Palmén Lorena. "Homotrimeric dUTPases : Principles of Catalysis and Inhibitor Design." Doctoral thesis, Högskolan i Kalmar, Naturvetenskapliga institutionen, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-6119.
Full textGurp, Jilles van. "Design Principles for Reusable, Composable and extensible Frameworks." Thesis, Blekinge Tekniska Högskola, Institutionen för programvaruteknik och datavetenskap, 1999. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-5380.
Full textAusman, Eman. "The digital design document strategies, principles and processes /." Menomonie, WI : University of Wisconsin--Stout, 2006. http://www.uwstout.edu/lib/thesis/2006/2006ausmane.pdf.
Full textXu, Dongjie. "Harmonious screen interface design principles from Chinese calligraphy." Thesis, University of Central Lancashire, 2010. http://clok.uclan.ac.uk/1521/.
Full textLee, Chao-Chin. "An investigation of the principles of design leadership." Thesis, University of Leeds, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422627.
Full textSou, Antony. "Principles of organic field effect transistor circuit design." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708548.
Full textHoward, Jeffrey (Jeffrey Rush) 1977. "Principles for design of software engineering visualization tools." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/86663.
Full textIncludes bibliographical references (leaves 60-71).
by Jeffrey Howard.
M.Eng.
Göransson, Andreas, and Fernando Barrajon. "Sketching a set of multi-touch design principles." Thesis, Malmö högskola, Fakulteten för kultur och samhälle (KS), 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-22583.
Full textChase, Davis William. "Architectural design principles as evidenced in Gothic architecture." Thesis, Virginia Polytechnic Institute and State University, 1985. http://hdl.handle.net/10919/53714.
Full textMaster of Science
Venngren, Evelina. "Applying Principles of Game Design to User Interface." Thesis, Uppsala universitet, Institutionen för speldesign, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-449220.
Full textHulshof, Ana Vitoria Joly. "Interactive television for young children : developing design principles." Thesis, University of Brighton, 2010. https://research.brighton.ac.uk/en/studentTheses/c20c561b-b374-460d-b48b-66ec3cc58729.
Full textLammert, L. (Laura). "Circular economy in architecture:sustainable principles for future design." Master's thesis, University of Oulu, 2018. http://urn.fi/URN:NBN:fi:oulu-201811233096.
Full textYhteiskunnassamme rakennusalla kulutetaan nykyään eniten energiaa ja haaskataan materiaaleja. Lineaarinen talous ei kestä nykyistä toimintatapaamme ja muutoksia saamme aikaan vain muuttamalla järjestelmää ja ajattelutapojamme. Diplomityössäni käsittelen kiertotalouden teoriaa ja sen hyödyntämistä rakentamisessa, sekä pohdin jäteongelmia sekä materiaalilähteitä. Myös purkutyö on rakentamisessa suuri saastuttaja ja siihen esitän ratkaisuksi rakennusten suunnittelemista purettaviksi. Diplomityöni tavoitteena on lisästä tietoisuutta kestävän suunnittelun aiheesta (nykyhetken viitekehyksessä) ja koota nämä tiedot yhteen. Monissa esittämistäni konsepteissa hyödynnetään olemassa olevia ideoita, kuten materiaalien saatavuutta ja uudelleenkäyttöä sekä jätteenhallintaa, mutta oleellista on kuinka kokonaisvaltaisesti niitä käytämme. Esimerkkiprojektien avulla havainnollistan konseptien sovellutuksia käytännössä. Lopuksi ehdotan käytännön esimerkein miten kestäviä suunnitteluideoita voi käyttää rakennetussa ympäristössä. Rakentamisessa hyvänä lähtökohtana voi pitää, että rakennusten tulisi olla purettavia, kierrätettäviä ja että uusissa rakennuksissa käytettäisiin uusiutuvia raaka-aineita
Ratanalert, Sakul. "Sequence design principles for 3D wireframe DNA origami." Thesis, Massachusetts Institute of Technology, 2018. https://hdl.handle.net/1721.1/121818.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (pages 143-151).
DNA is a highly programmable molecule that can be designed to self-assemble into nearly arbitrary 2D and 3D nanoscale structures. DNA origami is a particularly versatile method to achieve complex molecular architectures. However, the rules for designing scaffolded DNA origami have not been well-formalized, which hinders both the investigation of characteristics of well- and poorly-folded structures as well as the participation of a larger scientific audience in DNA nanotechnology. In my thesis work, a fully automatic inverse design procedure DAEDALUS (DNA Origami Sequence Design Algorithm for User-defined Structures) has been developed that programs arbitrary wireframe DNA assemblies based on an input wireframe mesh without reliance on user feedback. This general, top-down strategy is able to design nearly arbitrary DNA architectures, routing the scaffold strand using a spanning tree algorithm and adding staple strands in a prescribed manner. The wireframe nanoparticles produced can use antiparallel crossover (DX) motifs, for robust selfassembly, parallel paranemic crossover (PX) motifs, for staple-free self-assembly, or a hybrid of the two, to minimize the number of staples required for folding to the ones necessary for functionalization. The thermodynamics of the self-assembly of these wireframe structures, and the effects of scaffold and staple routing, are investigated using quantitative PCR and FRET measurements, tracking fluorescence to elucidate global and local folding events. The framework developed should enable the broad participation of nonexperts in this powerful molecular design paradigm and set the foundation for further predictive models of DNA self-assembly.
by Sakul Ratanalert.
Ph. D.
Ph.D. Massachusetts Institute of Technology, Department of Chemical Engineering
Tort, Ayala Laura Susana. "Principles and recommendations to design aging-friendly homes." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122341.
Full textCataloged from PDF version of thesis. "Some pages in the original document contain text that runs off the edge of the page. (See Appendix C)"--Disclaimer Notice page.
Includes bibliographical references (pages 82-84).
The aging population is increasing at an unprecedented rate, and with it, the number of older adults that decide to age in place. Some public and private efforts have been made in order to better understand the mobility and physical needs of older adults in home environments. However, most of these efforts have missed a holistic definition of home and how the human dwelling is influenced by aging. This thesis is composed of three studies: a national survey, a series of in-home interviews, and an intergenerational workshop. The overall objective of these studies was to understand how older adults live and move within their homes, as well as what their emotional and functional expectations of their homes are. The outcome of this work is a set of principles and recommendations that design professionals can use when designing home environments or home-related products. These principles and recommendations are meant to serve as a guide to approach a project with the right mindset-a mindset that augments empathy and understanding for older adults, and that challenges the preconceptions of what a home is and what it should do for us as we age.
by Laura Susana Tort Ayala.
S.M. in Engineering and Management
S.M.inEngineeringandManagement Massachusetts Institute of Technology, System Design and Management Program
SCHNEIDER, KARIN. "Fraction-an investigation on principles of functional design and its expressive potential." Thesis, Högskolan i Borås, Institutionen Textilhögskolan, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-17399.
Full textProgram: Konstnärligt masterprogram i mode- och textildesign med inriktning mot modedesign eller textildesign
Dong, Ren Wen. "The application of traditional Chinese aesthetic principles to contemporary international design." Thesis, University of Bedfordshire, 2006. http://hdl.handle.net/10547/344358.
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