Journal articles on the topic 'Design guides'
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Ribera-Navarro, Aida, Ravikiran Shenoy, Gregory Cunningham, Vejay Vakharia, Alexander Gibson, Mehran Moazen, and Deepak M. Kalaskar. "Patient-specific 3D-printed surgical guides for pedicle screw insertion: comparison of different guide design approaches." Journal of 3D Printing in Medicine 5, no. 2 (June 2021): 71–82. http://dx.doi.org/10.2217/3dp-2021-0002.
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Aim: Patient-specific 3D-printed guides for pedicle screw insertion in spinal deformity surgery offer an alternative to image-guided, robotic and free-hand methods. Different design features can impact their accuracy and clinical applicability. The aim of this study was to compare the performance of three different guide designs with the nonguided free-hand technique. Materials & methods: 3D-printed guides were design and tested using anatomical models of human spines and porcine cadaveric specimens. Three different guided groups (low, medium and full contact) and one nonguided group was formed. Results & conclusion: The design approach affected level of accuracy of screw placement. A variability in terms of accuracy of screw insertion between surgeon’s experience using nonguided/guided techniques was also observed, suggesting benefit for junior surgeons in improving surgical accuracy.
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Setiadi, Hermayawati. "Designing a Supplementary Reading Using Cultural Language Learning Approach (CLLA)." International Journal for Innovation Education and Research 5, no. 8 (August 31, 2017): 111–28. http://dx.doi.org/10.31686/ijier.vol5.iss8.794.
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This paper reports on a project findings concerning the design of a Supplementary Reading Book using Cultural Language Learning Approach ( CLLA). The project was conducted in Yogyakarta, Indonesia that generally aimed at designing supplementary reading materials using CLLA as a guide book for tourist guides who worked for Sonobudoyo Museum. The book is entitled “The Javanese Cultural Heritages Reserved in Sonobudoyo Museum (JCHRSM)”. This utilized a developmental research design, which consisted of three procedures, namely: (1) exploration, aiming to analyze the needs of the tour guides of Sonobudoyo Museum; (2) development, to design a supplementary reading guide book for the (candidate) tourist guides working for Sonobudoyo Museum; and (3) validation, to find the designed guide book accuracy. This study found: (1) The tour guides’ needs was JCHRSM using CLLA; (2) the designed book was matched with the tour guides’ needs; and (3) the designed guide book was judged accurate and compatible for Sonobudoyo tour guides. This was judged accurate since: (1) it was designed based on the results of the tour guide needs analysis and book’s content analysis as suggested by McDonough and McDonough; (2) the 12 times cyclical treatments resulted continually learning improvement on the trainees’ reading skills; and (3) the guide book validation through statistical analysis using Mean Difference (Md) formula and One-shot study experimental design yielded significant gain score between the average score of pretest and post-test, i.e. 8.2>5.6. Besides, the result of FGD (Focus Group Discussion) also indicated that the supplementary reading guide book was recommended as an alternative reference especially for Sonobudoyo tour guides.
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Popescu, Diana, Dan Laptoiu, Rodica Marinescu, and Iozefina Botezatu. "Design and 3D printing customized guides for orthopaedic surgery – lessons learned." Rapid Prototyping Journal 24, no. 5 (July 9, 2018): 901–13. http://dx.doi.org/10.1108/rpj-05-2017-0099.
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Purpose This paper aims to fill a research gap by presenting design and 3D printing guidelines and considerations which apply to the development process of patient-specific osteotomy guides for orthopaedic surgery. Design/methodology/approach Analysis of specific constraints related to patient-specific surgical guides design and 3D printing, lessons learned during the development process of osteotomy guides for orthopaedic surgery, literature review of recent studies in the field and data gathered from questioning a group of surgeons for capturing their preferences in terms of surgical guides design corresponding to precise functionality (materializing cutting trajectories, ensuring unique positioning and stable fixation during surgery), were all used to extract design recommendations. Findings General design rules for patient-specific osteotomy guides were inferred from examining each step of the design process applied in several case studies in relation to how these guides should be designed to fulfill medical and manufacturing (fused deposition modelling process) constraints. Literature was also investigated for finding other information than the simple reference that the surgical guide is modelled as negative of the bone. It was noticed that literature is focussed more on presenting and discussing medical issues and on assessing surgical outcomes, but hardly at all on guides’ design and design for additive manufacturing aspects. Moreover, surgeons’ opinion was investigated to collect data on different design aspects, as well as interest and willingness to use such 3D-printed surgical guides in training and surgery. Practical implications The study contains useful rules and recommendations for engineers involved in designing and 3D printing patient-specific osteotomy guides. Originality/value A synergetic approach to identify general rules and recommendations for the patient-specific surgical guides design is presented. Specific constraints are identified and analysed using three case studies of wrist, femur and foot osteotomies. Recent literature is reviewed and surgeons’ opinion is investigated.
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Dunst, Carl J. "Parents’ Social Validity Appraisals of Early Childhood Intervention Practice Guides." Journal of Educational and Developmental Psychology 7, no. 2 (July 4, 2017): 51. http://dx.doi.org/10.5539/jedp.v7n2p51.
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Findings from three field-tests of parents’ ratings of early childhood intervention practice guides are reported. Results from the first field-test were used to inform changes to the practice guides in the second field-test, and results from the second field-test were used to inform changes to the practice guides in the third field-test. Parents’ judgments of the practice guide designs and their social validity appraisals of the practice guide intervention activities and child outcomes were correlated with parent-informed improvements in the intervention materials. The results add to the knowledge base in terms of how parent-informed improvements to the practice guides are related to product design judgments and the social validity appraisals of the importance and acceptability of early childhood intervention materials.
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Pijpker, Peter A. J., Joep Kraeima, Max J. H. Witjes, D. L. Marinus Oterdoom, Maarten H. Coppes, Rob J. M. Groen, and Jos M. A. Kuijlen. "Accuracy Assessment of Pedicle and Lateral Mass Screw Insertion Assisted by Customized 3D-Printed Drill Guides: A Human Cadaver Study." Operative Neurosurgery 16, no. 1 (April 5, 2018): 94–102. http://dx.doi.org/10.1093/ons/opy060.
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Abstract BACKGROUND Accurate cervical screw insertion is of paramount importance considering the risk of damage to adjacent vital structures. Recent research in 3-dimensional (3D) technology describes the advantage of patient-specific drill guides for accurate screw positioning, but consensus about the optimal guide design and the accuracy is lacking. OBJECTIVE To find the optimal design and to evaluate the accuracy of individualized 3D-printed drill guides for lateral mass and pedicle screw placement in the cervical and upper thoracic spine. METHODS Five Thiel-embalmed human cadavers were used for individualized drill-guide planning of 86 screw trajectories in the cervical and upper thoracic spine. Using 3D bone models reconstructed from acquired computed tomography scans, the drill guides were produced for both pedicle and lateral mass screw trajectories. During the study, the initial minimalistic design was refined, resulting in the advanced guide design. Screw trajectories were drilled and the realized trajectories were compared to the planned trajectories using 3D deviation analysis. RESULTS The overall entry point and 3D angular accuracy were 0.76 ± 0.52 mm and 3.22 ± 2.34°, respectively. Average measurements for the minimalistic guides were 1.20 mm for entry points, 5.61° for the 3D angulation, 2.38° for the 2D axial angulation, and 4.80° for the 2D sagittal angulation. For the advanced guides, the respective measurements were 0.66 mm, 2.72°, 1.26°, and 2.12°, respectively. CONCLUSION The study ultimately resulted in an advanced guide design including caudally positioned hooks, crosslink support structure, and metal inlays. The novel advanced drill guide design yields excellent drilling accuracy.
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Liu, Weiling. "Knowledge map: a creative visual path to library guides and resources." Electronic Library 38, no. 5/6 (November 26, 2020): 943–62. http://dx.doi.org/10.1108/el-03-2020-0055.
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Purpose This paper aims to indicate that library guides seem to be unfamiliar to most students or not easy to find or use. Some improvements have been made by embedding the guides in the learning management system or promoting the guides in formal library instructional classes. Are there other ways to promote or improve the use of library guides? The author proposes an exploratory visual solution to minimize this gap between library users and library guides. Design/methodology/approach Guided by the cognitive load theory, the proposed solution is a knowledge map created with Freeplane. The proposal is illustrated by comparing a sample knowledge map with its content source, a subject guide in LibGuides, via three browsing paths in locating a recommended database for a particular course on the sample subject guide website. Findings The knowledge map can display contents in different ways and provide a simple and visual layout with direct access to the library resources, which may help lessen users’ intrinsic cognitive load, minimize extraneous load or promote germane load. The map can also be beneficial to librarians for preparing teaching materials or guides management. Practical implications The proposed solution can be implemented with Freeplane based on existing library guides or created from scratch. Originality/value The proposed solution addresses a gap in the library field, where the use of knowledge maps for library services is overlooked.
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Sosnovskiy, A. Yu, B. E. Murmanskiy, and Yu M. Brodov. "Investigation of operational characteristics of axial displacement guides for thermal expansion systems of steam turbines." Power engineering: research, equipment, technology 23, no. 4 (October 13, 2021): 105–19. http://dx.doi.org/10.30724/1998-9903-2021-23-4-105-119.
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ТНЕ PURPOSE. To carry out a comparative analysis of the performance characteristics of the longitudinal movement guides of the external bearing housings of steam turbines, using the principle of rotation to ensure full contact of their lateral surfaces with the lateral surfaces of the guide groove at the base of the external bearing housing of the steam turbine. Compare the manufacturability of elements and their implementation for both existing and newly developed steam turbines .METHODS. The permissible transverse forces are determined from the strength conditions and compared for the traditional design of fixed longitudinal guides and the design of guides, in which the principle of rotation is used to avoid "biting" of the bearing housing on the guides when temperature misalignment appears along the flanges of the turbine cylinder. Also, the allowable forces are determined and compared from the condition of the absence of plastic deformations in any of the elements of the interface of the guides, the base frame and the bearing housing. Based on the results obtained, the value of the permissible temperature misalignment along the flanges of the turbine cylinder is estimated. The analysis was carried out in relation to the operating conditions of the front bearing housing and HPC of turbines of the T 100/120-130 UTZ family.RESULTS. It has been established that all the considered designs of guides with pivoting elements make it possible to exclude the occurrence of plastic deformations in the junction of the base frame and the outboard bearing housing at a temperature misalignment of 20°C regulated in most turbine operating instructions. CONCLUSION. The design of longitudinal keys proposed by UTZ does not require a change in the technology for manufacturing the foundation frames and allows the unit to be modernized during repairs in a CHP. The best performance disc guide design can be used in new turbine designs or factory retrofits.
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Sosnovskiy, A. Yu, B. E. Murmanskiy, and Yu M. Brodov. "Investigation of operational characteristics of axial displacement guides for thermal expansion systems of steam turbines." Power engineering: research, equipment, technology 23, no. 4 (October 13, 2021): 105–19. http://dx.doi.org/10.30724/1998-9903-2021-23-4-105-119.
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ТНЕ PURPOSE. To carry out a comparative analysis of the performance characteristics of the longitudinal movement guides of the external bearing housings of steam turbines, using the principle of rotation to ensure full contact of their lateral surfaces with the lateral surfaces of the guide groove at the base of the external bearing housing of the steam turbine. Compare the manufacturability of elements and their implementation for both existing and newly developed steam turbines .METHODS. The permissible transverse forces are determined from the strength conditions and compared for the traditional design of fixed longitudinal guides and the design of guides, in which the principle of rotation is used to avoid "biting" of the bearing housing on the guides when temperature misalignment appears along the flanges of the turbine cylinder. Also, the allowable forces are determined and compared from the condition of the absence of plastic deformations in any of the elements of the interface of the guides, the base frame and the bearing housing. Based on the results obtained, the value of the permissible temperature misalignment along the flanges of the turbine cylinder is estimated. The analysis was carried out in relation to the operating conditions of the front bearing housing and HPC of turbines of the T 100/120-130 UTZ family.RESULTS. It has been established that all the considered designs of guides with pivoting elements make it possible to exclude the occurrence of plastic deformations in the junction of the base frame and the outboard bearing housing at a temperature misalignment of 20°C regulated in most turbine operating instructions. CONCLUSION. The design of longitudinal keys proposed by UTZ does not require a change in the technology for manufacturing the foundation frames and allows the unit to be modernized during repairs in a CHP. The best performance disc guide design can be used in new turbine designs or factory retrofits.
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Donovan, Jason, Steven Franzel, Marcelo Cunha, Amos Gyau, and Dagmar Mithöfer. "Guides for value chain development: a comparative review." Journal of Agribusiness in Developing and Emerging Economies 5, no. 1 (May 18, 2015): 2–23. http://dx.doi.org/10.1108/jadee-07-2013-0025.
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Purpose – In recent years, governments, donors, and NGOs have increasingly embraced value chain development (VCD) for stimulating economic growth and combating rural poverty. In line with the rise in interest, there has been a proliferation of guides for VCD. The purpose of this paper is to present the results of a review of 11 guides for value chain along six different dimensions, ranging from objectives and value chain definitions to monitoring impact. The paper concludes with suggestions for the use of guides based on local needs and context, and recommendations for future guide development. Design/methodology/approach – The review compares the concepts and methods endorsed and it assesses the strengths and limitations of the guides for steering development practice. Findings – Overall, the guides provide a useful framework for understanding markets and engaging with chain stakeholders, with a strong emphasis on strengthening institutions and achieving sustainability of interventions. However, the guides often lack discussions on the conditions necessary at different levels for VCD to advance development objectives and achieve that sustainability. The guides are designed to be implemented largely independently of the specific context, in which the chain is situated, despite the major implications context has for the design of interventions and overall success of the chain. Attention to mutual learning, whether related to tool design or the outcomes and impacts of VCD interventions, is limited. Research limitations/implications – More critical reflection and debate is needed on the design of guides for VCD. The authors suggest three areas for this reflection and debate: concepts, methods, and tools for addressing the needs of the poor in value chains; tools for addressing variations in the context; and mechanisms for mutual learning on the design and implementation of VCD. Originality/value – The paper concludes with various recommendations for guide authors and donors that support VCD.
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Daniel, Dominique. "Embedded Library Guides in Learning Management Systems Help Students Get Started on Research Assignments." Evidence Based Library and Information Practice 11, no. 1 (March 15, 2016): 76. http://dx.doi.org/10.18438/b8j32h.
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Murphy, S. A. & Black, E. L. (2013). Embedding guides where students learn: Do design choices and librarian behavior make a difference? The Journal of Academic Librarianship, 39(6), 528-534. http://dx.doi.org/10.1016/j.acalib.2013.06.007
Abstract
Objective – To determine whether library guides embedded in learning management systems (LMS) get used by students, and to identify best practices for the creation and promotion of these guides by librarians.
Design – Mixed methods combining quantitative and qualitative data collection and analysis (survey, interviews, and statistical analysis).
Setting – A large public university in the United States of America.
Subjects – 100 undergraduate students and 14 librarians.
Methods – The researchers surveyed undergraduate students who were participating in a Project Information Literacy study about their use of library guides in the learning management system (LMS) for a given quarter. At that university, all course pages in the LMS are automatically assigned a library guide. In addition, web usage data about the course-embedded guides was analyzed and high use guides were identified, namely guides that received an average of at least two visits per student enrolled in a course. The researchers also conducted a qualitative analysis of the layout of the high use guides, including the number of widgets (or boxes) and links. Finally, librarians who created high use library guides were interviewed. These mixed methods were designed to address four research questions: 1) Were students finding the guides in the LMS, and did they find the guides useful? 2) Did high use guides differ in design and composition? 3) Were the guides designed for a specific course, or for an entire department or college? and, 4) How did the librarians promote use?
Main Results – Only 33% of the students said they noticed the library guide in the LMS course page, and 21% reported using the guide. Among those who used the guide, the majority were freshmen (possibly because embedding of library guides in the LMS had just started at the university). Library guides with high use in relation to class enrollment did not significantly differ from low use guides in terms of numbers of widgets and links, although high use guides tended to have slightly fewer widgets. Of those guides, 55% were assigned at the course level, 30% at the department level and 13% at the college level. Over half the librarians with at least one high use guide conducted a library instruction session in which they used or promoted that guide. For 39% of the courses with high-use guides, the librarian was actively engaged with the faculty and students via the LMS, but others reported no specific involvement in courses.
Conclusion – Those students who used library guides reported the guides helped them get started on their research paper or assignment and find research materials, two areas for which previous studies show students have great difficulty. Since the majority of students did not notice the link to the library guide in the LMS, librarians could emphasize it in the news section of the course, which gets much more attention. Within library guides, simpler groupings of links might be easier for students to use, but this conclusion would require further research to confirm. In any case, nearly half of all high use guides were not promoted in any way by librarians, but simply automatically embedded in the LMS, a sign that passive embedding may provide an easy way for the library to reach a large number of students early in their academic career. Since the automatic embedding of guides began, guides have seen a dramatic increase in usage.
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Antoniou, Angeliki, Maria Vayanou, Akrivi Katifori, Angeliki Chrysanthi, Filippia Cheilitsi, and Yannis Ioannidis. "“Real Change Comes from Within!”: Towards a Symbiosis of Human and Digital Guides in the Museum." Journal on Computing and Cultural Heritage 15, no. 1 (February 28, 2022): 1–19. http://dx.doi.org/10.1145/3465557.
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Extensive research on mobile guides for museums has explored the potential of technology to offer some of the services that have been traditionally provided by human guides, including guiding visitors in the museum space, providing information about the exhibits, and using more advanced interpretative approaches such as digital storytelling and gamified techniques. However, the majority of these approaches either ignores or tries to substitute entirely the role of the human guide. In this work, we present a user study with 10 experienced tour guides, currently working in the museum of modern art of the Basil & Elise Goulandris Foundation. Based on a three-phase procedure, the study is designed to empower professionals into envisaging their work in symbiosis with current technological developments. First, we attempt to identify existing challenges guides face and to capture their tacit knowledge in addressing emerging problems in guided tours. In the second and third stage, through a reflective and productive discussion, we employ a set of contemporary innovative digital applications as a starting point to elicit their views on their role in an envisaged symbiotic future of human-led hybrid digital experiences.
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Hinckfuss, Simon, Heather J. Conrad, Lianshan Lin, Scott Lunos, and Wook-Jin Seong. "Effect of Surgical Guide Design and Surgeon's Experience on the Accuracy of Implant Placement." Journal of Oral Implantology 38, no. 4 (August 1, 2012): 311–23. http://dx.doi.org/10.1563/aaid-joi-d-10-00046.
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Implant position is a key determinant of esthetic and functional success. Achieving the goal of ideal implant position may be affected by case selection, prosthodontically driven treatment planning, site preparation, surgeon's experience and use of a surgical guide. The combined effect of surgical guide design, surgeon's experience, and size of the edentulous area on the accuracy of implant placement was evaluated in a simulated clinical setting. Twenty-one volunteers were recruited to participate in the study. They were divided evenly into 3 groups (novice, intermediate, and experienced). Each surgeon placed implants in single and double sites using 4 different surgical guide designs (no guide, tube, channel, and guided) and written instructions describing the ideal implant positions. A definitive typodont was constructed that had 3 implants in prosthetically determined ideal positions of single and double sites. The position and angulation of implants placed by the surgeons in the duplicate typodonts was measured using a computerized coordinate measuring machine and compared to the definitive typodont. The mean absolute positional error for all guides was 0.273, 0.340, 0.197 mm in mesial-distal, buccal-lingual, vertical positions, respectively, with an overall range of 0.00 to 1.81 mm. The mean absolute angle error for all guides was 1.61° and 2.39° in the mesial-distal and buccal-lingual angulations, respectively, with an overall range of 0.01° to 9.7°. Surgical guide design had a statistically significant effect on the accuracy of implant placement regardless of the surgeon's experience level. Experienced surgeons had significantly less error in buccal-lingual angulation. The size of the edentulous sites was found to affect both implant angle and position significantly. The magnitude of error in position and angulation caused by surgical guide design, surgeon's experience, and site size reported in this study are possibly not large enough to be clinically significant; however, it is likely that errors would be magnified in clinical practice. Future research is recommended to evaluate the effect of surgical guide design in vivo on implant angulation and position error.
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Purbono, Heri. "Development of Learning Packages to Strengthening Character Education in Civic Education for Vocational Students." IMTECH: Journal of Instructional, Media Education and Technology 1, no. 1 (June 1, 2020): 24–41. http://dx.doi.org/10.47387/imtech.v1i1.11.
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Research and development is intended to produce products such as reinforcement learning packages in PPKn character education that includes teaching materials, teacher guides, and guides students eligible to use and can improve the quality of learning in an effective, efficient, and attractive. This development model Dick Carey on systemic and procedural. The procedure researched the development of these activities includes nine steps. Product validation test conducted by three experts. The experts of the course content, instructional design experts, and expert instructional media. The field trials in SMK Negeri PP Sembawa with the subjects involved are X class learners majoring second-semester plantation some 33 people and a teacher PPKn subjects. The results showed that the learning package is very feasible to use and very effective. Data were obtained: (1) the results of expert validation of the course content to the percentage of teaching materials (89%), teacher guides (90%), and guide students (90%), (2) the results of expert validation of instructional design for the percentage teaching materials (92%), teacher guides (97%), and guide students (92%), (3) the results of expert validation media the percentage of teaching materials (99%), teacher guides (98%), and guide students (98% ), (4) the results of individual testing for the percentage of teaching materials (89%), guides the students (91%), (5) the small group trial percentage of teaching materials (96%), guides the students (97%), (6 ) the results of field trials the percentage of instructional materials (93%), guide students (95%), and teacher guidance (98%) and from the assessment of 33 students, the results were very effective, namely 100% of students reached the KKM with excellent attitudes and skills.
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Pendell, Kimberly, and Annie Armstrong. "Psychology guides and information literacy." Reference Services Review 42, no. 2 (June 3, 2014): 293–304. http://dx.doi.org/10.1108/rsr-10-2013-0052.
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Purpose – This study aims to provide an understanding of current practice and informs the further development of guides as key instructional tools. To assess the existing landscape of research guides as instructional tools, researchers examined the instructional content and associated media formats of online psychology research guides. Design/methodology/approach – Researchers devised an instrument utilizing Standard Two of the Association of College and Research Libraries’ (ACRL’s) Psychology Information Literacy Standards and inventoried the instructional content and associated media formats of a sample set of 36 psychology research guides. Findings – Although online research guides offer a platform for presenting instructional content in myriad formats, it was found that the sample set of psychology research guides rarely incorporated instructional content. Research limitations/implications – Psychology course guides were not part of the sample set; it is possible that guide authors approach the addition of instructional content in course guides differently than in general psychology subject guides. Practical implications – This paper provides an overview of how libraries are, or are not, using research guides as part of their instruction program. The researchers propose a framework for adding instructional content to psychology guides using Standard Two. Originality/value – Considering the ubiquity of online research guides on academic library Web sites, little research on the existing integration of instructional content into guides has been published. This study offers a snapshot of current guide practice and proposes a practical, systematic and unique model for aligning information literacy standards with guide content areas which has not been proposed elsewhere.
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Anil Kumar CH, Ramana Kumar K.V., Paul T Joyes, and Padmanabhan P. "Open Surgical Guides – A Novel Concept in Computer Guided Implantology." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (December 25, 2020): 817–22. http://dx.doi.org/10.26452/ijrps.v11ispl4.4079.
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Dental implants have become so popular that more than 5 million implants are placed each year by dentists in the United States alone. However, it is generally observed that a majority of implants are placed in a less-than-ideal manner. Computer-guided surgeries are proven to have a positive impact on implant placement as well as implant treatment planning. But, despite the indisputable compensations, only a partial number of clinicians regularly practice directed transplant surgery nowadays. This article aims to examine the challenges in guided implant surgery and how a novel concept of the open guide is trying to solve these issues. The latter was used during a CT scan and was eventually converted into an actual surgical guide. However, using conventional guides is not a guarantee for proper implant placement. The reason for that was inherent in their design. Conventional guides take marvelous leeway in the drilling trajectory and no drilling depth control. Using them relies on several variables that may not be trustworthy, such as hand stability, patient immobility, and another person’s feedback on the drilling angle. Bone quality can also affect the osteotomy in situations of immediate implant placement, as the drills commonly bounce off dense bone affecting the angulation and point of entry. From a safety perspective, conventional guides do not consider the patient’s relevant anatomy.
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Temple, Norman J. "Fruits, Vegetables, and Food Guides: Design Challenges." Community Medicine and Public Health Care 7, no. 1 (August 14, 2020): 1–5. http://dx.doi.org/10.24966/cmph-1978/100064.
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Whitehead, Lorne A., Peter Kan, and Kris Lui. "Improved Extractor Design for Modular Light Guides." Journal of the Illuminating Engineering Society 28, no. 2 (July 1999): 10–15. http://dx.doi.org/10.1080/00994480.1999.10748271.
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van der Meij, Jan, Marije van Amelsvoort, and Anjo Anjewierden. "How design guides learning from matrix diagrams." Instructional Science 45, no. 6 (September 13, 2017): 751–67. http://dx.doi.org/10.1007/s11251-017-9425-1.
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Lehmann, B. F., and S. G. Hutton. "Self-Excitation in Guided Circular Saws." Journal of Vibration and Acoustics 110, no. 3 (July 1, 1988): 338–44. http://dx.doi.org/10.1115/1.3269522.
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The paper presents the results of an experimental and analytical study into the vibrational characteristics of guided rotating saw blades that are not perfectly flat. Experimental results are presented that show the nature of the vibrations induced by the interaction between the guides and the blade. An analytical model is developed that includes the effect of the interaction between the guide and the blade, and this model may be used as a design tool in avoiding the self-excited resonances that exist in the coupled blade/guide system.
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Neuhaus, Michael-Tobias, Alexander-Nicolai Zeller, Alexander K. Bartella, Anna K. Sander, Bernd Lethaus, and Rüdiger M. Zimmerer. "Accuracy of Guided Surgery and Real-Time Navigation in Temporomandibular Joint Replacement Surgery." Dentistry Journal 9, no. 8 (August 2, 2021): 87. http://dx.doi.org/10.3390/dj9080087.
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Background: Sophisticated guided surgery has not been implemented into total joint replacement-surgery (TJR) of the temporomandibular joint (TMJ) so far. Design and in-house manufacturing of a new advanced drilling guide with vector and length control for a typical TJR fossa component are described in this in vitro study, and its accuracy/utilization was evaluated and compared with those of intraoperative real-time navigation and already available standard drilling guides. Methods: Skull base segmentations of five CT-datasets from different patients were used to design drilling guides with vector and length control according to virtual surgical planning (VSP) for the TJR of the TMJ. Stereolithographic models of the skull bases were printed three times for each case. Three groups were formed to compare our newly designed advanced drilling guide with a standard drilling guide and drill-tracking by real-time navigation. The deviation of screw head position, screw length and vector in the lateral skull base have been evaluated (n = 72). Results: There was no difference in the screw head position between all three groups. The deviation of vector and length was significantly lower with the use of the advanced drilling guide compared with standard guide and navigation. However, no benefit in terms of accuracy on the lateral skull base by the use of real-time navigation could be observed. Conclusion: Since guided surgery is standard in implant dentistry and other CMF reconstructions, this new approach can be introduced into clinical practice soon, in order to increase accuracy and patient safety.
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Moreton, Leo. "The communication of architectural design analysis in residential design guidance: legibility, commodity and design." Town Planning Review: Volume 91, Issue 5 91, no. 5 (September 1, 2020): 489–513. http://dx.doi.org/10.3828/tpr.2020.28.
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This article will propose new approaches to the representation of architectural design principles, in residential design guidance. The visual appearance of new development is key in its successful integration of new housing in historic environments, providing an important means of analysis for planning departments and client users and establishing key information for developers regarding local-authority expectations and the contextualisation of proposed schemes. An epistemological analysis of content in 98 currently accessible guides identified a need for a more concise and accessible approach to architectural analysis. This figure is representative of a majority of residential design guides in England. A greater understanding of the visual impact of architectural design decisions is key in ensuring the continuity of the built environment. This research is more widely significant in terms of consolidating architectural design approaches in design guidance, as many authorities and bodies have adopted similar approaches globally.
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Yuan, Fusong, Yao Sun, Lei Zhang, and Yuchun Sun. "Accuracy of chair-side fused-deposition modelling for dental applications." Rapid Prototyping Journal 25, no. 5 (June 10, 2019): 857–63. http://dx.doi.org/10.1108/rpj-04-2018-0082.
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Purpose The purpose of this paper is to establish a chair-side design and production method for a tooth-supported fixed implant guide and to evaluate its accuracy. Design/methodology/approach Three-dimensional (3D) data of the alveolar ridge, adjacent teeth and antagonistic teeth were acquired from models of the edentulous area of 30 patients. The implant guides were then constructed using self-developed computer-aided design software and chair-side fused deposition modelling 3D-printing and positioned on a dental model. A model scanner was used to acquire 3D data of the positioned implant guides, and the overall error was then evaluated. Findings The overall error was 0.599 ± 0.146 mm (n = 30). One-way ANOVA revealed no statistical differences among the 30 implant guides. The gap between the occlusal surface of the teeth covering and the tissue surface of the implant guide was measured. The maximum gap after positioning of the implant guide was 0.341 mm (mean, 0.179 ± 0.019 mm). The implanted axes of the printed implant guide and designed guide were compared in terms of overall, lateral and angular error, which were 0.104 ± 0.004 mm, 0.097 ± 0.003 mm, and 2.053° ± 0.017°, respectively. Originality/value The results of this study demonstrated that the accuracy of a new chair-side tooth-supported fixed implant guide can satisfy clinical requirements.
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Furay, Julia. "Performance review: online research guides for theater students." Reference Services Review 46, no. 1 (February 12, 2018): 91–109. http://dx.doi.org/10.1108/rsr-09-2017-0037.
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Purpose This study aims to assess current academic library services to theater students through an examination of online research guides. Design/methodology/approach This study uses a representative sample of 100 universities that offer theater degrees; the library website at each of these institutions is examined for the existence of a theater research guide. Each research guide was analyzed in depth. Findings The vast majority of the universities in the sample did create research guides for theater students, though the contents of these guides varied greatly. The study highlights findings including popular databases and journals for theater students, as well as media resources and common subjects for subsections or course guides. Research limitations/implications This study only examined a sample of 100 institutions; many theater research guides were not examined for this study. Additionally, analysis of online content is a time-specific endeavor: a guide may look significantly different from one month to the next, though the recommendations in this article might prove useful even if the sites at these institutions have since been updated. Practical implications Through an examination of a great number of guides, a few practical suggestions emerge for librarians looking to create theater research guides, such as highlighting playscripts and other print materials and including hyperlocal information (such as university production history). Originality/value Though several studies have been performed on research guides in various disciplines, this article is the first on those to theater students.
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Flora, Stephen R., and Richard E. Logan. "Using Computerized Study Guides to Increase Performance on General Psychology Examinations: An Experimental Analysis." Psychological Reports 79, no. 1 (August 1996): 235–41. http://dx.doi.org/10.2466/pr0.1996.79.1.235.
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The effectiveness of using a commercially available computerized study guide to improve performance on examinations in two general psychology courses was investigated. The experimental design required 37 students to use a computerized study guide on two examinations and not on two others, counterbalanced across two classes. Analysis suggested that use of the study guides was associated with an increase in examination scores. These commercially available computerized study guides may be effective because they use many empirically established general principles of learning.
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Curtis, John M. "Elements of Behavioral Health Intervention in Geriatric Long-Term Care Settings." Psychological Reports 79, no. 1 (August 1996): 24–26. http://dx.doi.org/10.2466/pr0.1996.79.1.24.
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The effectiveness of using a commercially available computerized study guide to improve performance on examinations in two general psychology courses was investigated. The experimental design required 37 students to use a computerized study guide on two examinations and not on two others, counterbalanced across two classes. Analysis suggested that use of the study guides was associated with an increase in examination scores. These commercially available computerized study guides may be effective because they use many empirically established general principles of learning.
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Kartik, V., and J. A. Wickert. "Surface Friction Guiding for Reduced High-Frequency Lateral Vibration of Moving Media." Journal of Vibration and Acoustics 129, no. 3 (October 25, 2006): 371–79. http://dx.doi.org/10.1115/1.2732354.
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The free and forced vibration of a moving medium is examined in an application where distributed friction guiding is used to control lateral position passively. Subambient pressure features formed in the guides intentionally modify the naturally occurring self-pressurized air bearing and increase the contact force between the medium and the guide’s surface. These features increase friction to a level beyond that achievable based on the nominal wrap pressure. The moving medium is modeled as a beam that is transported over frictional regions and subjected to prescribed boundary disturbances arising from runout of a supply or take-up roll. For axial transport at a speed that is high compared to the velocity of lateral vibration, Coulomb friction between the guides and the moving medium can be well approximated by a derived expression for equivalent viscous damping. The equation of motion is developed for the cases of a single cylindrical guide and of a multiplicity of guides having arbitrary placement. The level of equivalent damping for each mode decreases with transport speed, and critical speeds exist where each vibration mode transitions between the overdamped and underdamped regimes. Parameter studies in the contact pressure, transport speed, and guide geometry identify preferred design configurations for maximizing dissipation in particular modes and for attenuating high-frequency response.
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Barker, Amy, and Ashley Hoffman. "Student-Centered Design: Creating LibGuides Students Can Actually Use." College & Research Libraries 82, no. 1 (2021): 75. http://dx.doi.org/10.5860/crl.82.1.75.
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In this mixed-methods study, librarians at Kennesaw State University Library System conducted a year-long design research project to create a flexible subject guide “blueprint” for undergraduate students using LibGuides. Methods included a card sorting study with 18 undergraduate students and usability testing with 40 undergraduate students. The study’s goals were to identify what content, aesthetic design, organization, and structure students preferred on a subject guide. This paper addresses the current literature on research guides usability, overviews the design and implementation of the study, and highlights practical results that will easily be transferrable to other libraries.
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Luesse, Hiershenee B., Pamela Koch, and Isobel R. Contento. "Applying the nutrition education DESIGN procedure to the development of the In Defence of Food Curriculum." Health Education Journal 78, no. 7 (May 22, 2019): 824–38. http://dx.doi.org/10.1177/0017896919850597.
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Objective: This study describes the use of the Nutrition Education DESIGN Procedure for developing the In Defence of Food Curriculum, a health education curriculum serving as the companion guide to the In Defence of Food documentary film based on the book with the same title. Design: The DESIGN Procedure is a systematic stepwise framework that produces behaviourally focused, theory-driven health education programmes and evaluation plans. Methods: DESIGN begins with an audience assessment and literature review that guides the selection of desired behaviours and psycho-social theory. For the In Defence of Food Curriculum, the desired behaviour changes were increased intake of whole/minimally processed plant-based foods and decreased intake of highly processed foods. A theoretical framework combining social cognitive and social determination theories guided programme development and evaluation plans. Education theory guided translating this framework into a ready-to-deliver curriculum. DESIGN aims to ensure alignment of theory determinants/mediators, behaviour change strategies, objectives, instructional activities and evaluation measures for systematically addressing desired behaviour changes. Over the course of 10 lessons, young people participate in interactive activities that explore the benefits of healthy eating, while appreciating how the ubiquity of heavily marketed and highly processed foods make healthy eating challenging. The evaluation plan guides measurement of target behaviours and the theory-based determinants/mediators. Results: This case study describes the development of the In Defence of Food curriculum using the DESIGN Procedure and demonstrates how a comprehensive and structured method for health education curriculum development and evaluation planning can be applied. Conclusion: The DESIGN Procedure has relevance for researchers, practitioners and programme planners.
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Guan, Xin-Hua, and Tzung-Cheng Huan. "Talent management for the proactive behavior of tour guides." International Journal of Contemporary Hospitality Management 31, no. 10 (October 14, 2019): 4043–61. http://dx.doi.org/10.1108/ijchm-07-2018-0596.
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Purpose In an increasingly competitive market, tourism managers are aware of the importance of talent management. Because tour guide behavior has an important influence on tourists’ experience in the process of group touring, how to motivate a tour guide’s proactive behavior becomes an important issue. Based on social exchange and cognitive theory, the purpose of this paper is to examine the impact of particular human resource management practices on proactive behavior. Design/methodology/approach This research takes the tour guide as the research object. The questionnaire survey method was used to obtain data. At last, 351 valid questionnaires were obtained. Finally, the hypotheses of this research are tested using structural equation modeling and percentile (bias-corrected percentile) bootstrapping method. Findings The results show that human resource management practices positively influenced proactive behavior of tour guides. Moreover, both perceived organizational support and self-efficacy were found to mediate the relationship between human resource management practice and proactive behavior. Originality/value This study contributes to the tourism literature by finding that both perceived organizational support and self-efficacy can foster the effect of human resource management practice, resulting in proactive behavior of tour guides.
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Jariyapongpaiboon, Prajak, Jirawan Chartpitak, and Jaturong Jitsaard. "The accuracy of computer-aided design and manufacturing surgical-guide for infrazygomatic crest miniscrew placement." APOS Trends in Orthodontics 11 (April 10, 2021): 48–55. http://dx.doi.org/10.25259/apos_127_2020.
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Objectives: Infrazygomatic crest (IZC) surgical guides have been employed to prevent any avoidable complications during miniscrew insertion. The purpose of this study was to evaluate the accuracy of IZC miniscrew placement when using a surgical-guide developed by computer-aided design and manufacturing (CAD/CAM) techniques. Materials and Methods: Ten patients were scanned with cone-beam computed tomography for three-dimensional (3D) planning of IZC miniscrew placements. The upper arches were scanned separately, and virtual miniscrews were placed in the position planned by 3D software. The CAD/CAM surgical guides were designed and fabricated individually to enable accurate miniscrew placement. Subsequently, 20 self-drilling miniscrews were inserted at the right and left IZC areas using 5 CAD/CAM surgical guides (CS group, n = 10) and direct insertion (DI group, n = 10), respectively. Pre- and post-operative digital model images were compared, actual and planned miniscrew positions were superimposed and measured for 3D angular and distance deviations in the two groups. Comparisons between groups were made using the Kruskal–Wallis test. Results: In the CS group, the median coronal and sagittal angular deviations were 2.95 degrees (range 0.34–5.26 degrees) and 2.05 degrees (range 0.38–4.08 degrees), respectively, while the median coronal and apical deviations were 0.39 mm (range 0.24–0.51 mm) and 0.50 mm (range 0.16–0.66 mm). These deviations differed significantly from those of the DI group. Conclusion: The IZC CAD/CAM surgical guide has made it possible to control miniscrew placement with high precision.
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Meier, Joshua A., Feng Zhang, and Neville E. Sanjana. "GUIDES: sgRNA design for loss-of-function screens." Nature Methods 14, no. 9 (September 2017): 831–32. http://dx.doi.org/10.1038/nmeth.4423.
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Matwankar, SKP. "Design and Development Guides Hospital and Healthcare Facilities." Medical Journal Armed Forces India 53, no. 2 (April 1997): 153. http://dx.doi.org/10.1016/s0377-1237(17)30700-1.
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Ruiz, Belén, José Luis Pajares, Francisco Utray, and Lourdes Moreno. "Design for All in multimedia guides for museums." Computers in Human Behavior 27, no. 4 (July 2011): 1408–15. http://dx.doi.org/10.1016/j.chb.2010.07.044.
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Güney, Elif, Mürsel Alper, and Mürşide Hacıismailoğlu. "Optical design of light guide prisms with surface roughness for automotive tail lights." Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering 234, no. 9 (April 14, 2020): 2393–401. http://dx.doi.org/10.1177/0954407020907209.
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This study presents the optical design of light guide prisms for automotive tail light applications to obtain the optimum luminous intensity and the illuminance uniformity. The design was achieved using optical design software, SPEOS. By considering the axial luminous intensity and legal requirements, the optimum prism angles of light guides were determined by simulations. After determining the prism angles, the effect of different surface roughness on the luminous intensity and the illuminance uniformity was investigated. The light guides designed by considering data from the simulation were manufactured as prototypes and their photometrical measurements were made. These measurements were compared to the simulation results. It was observed that simulation and prototype results are well in agreement with each other. Furthermore, it was found that as the surface roughness increases both the luminous intensity decreases and the illumination becomes more uniform.
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Lundy, Rochelle, and Reilly Curran. "Desperately seeking funding: library guides to student funding." Reference Services Review 48, no. 3 (July 23, 2020): 415–31. http://dx.doi.org/10.1108/rsr-03-2020-0021.
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Purpose This study aims to examine online research guides as a measure of academic library support for students seeking educational funding opportunities. Design/methodology/approach The library websites of 38 members of a regional academic library consortium were examined for guides that address funding for educational purposes. The guide content was manually reviewed. Information regarding institutional characteristics was gathered from the Carnegie Classification of Institutions of Higher Education. Findings Despite relatively few reports of educational funding support in the library literature, online guides exist at 42% of studied institutions. However, few guides are comprehensive and many lack features that promote discoverability. Instructional content – guidance, advice or information beyond resource descriptions – and in-person funding support rarely appear in the studied guides, presenting opportunities for academic libraries to contribute to student retention and success. Practical implications This paper provides information on and examples of online guides to educational funding useful to academic libraries looking to support students facing affordability concerns. Originality/value This paper contributes to the literature on non-disciplinary uses of online research guides and is the first to survey academic library guides on educational funding opportunities.
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Gugnani, Shashank, Arjun Kashyap, and Xiaoyi Lu. "Understanding the idiosyncrasies of real persistent memory." Proceedings of the VLDB Endowment 14, no. 4 (December 2020): 626–39. http://dx.doi.org/10.14778/3436905.3436921.
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High capacity persistent memory (PMEM) is finally commercially available in the form of Intel's Optane DC Persistent Memory Module (DCPMM). Researchers have raced to evaluate and understand the performance of DCPMM itself as well as systems and applications designed to leverage PMEM resulting from over a decade of research. Early evaluations of DCPMM show that its behavior is more nuanced and idiosyncratic than previously thought. Several assumptions made about its performance that guided the design of PMEM-enabled systems have been shown to be incorrect. Unfortunately, several peculiar performance characteristics of DCPMM are related to the memory technology (3D-XPoint) used and its internal architecture. It is expected that other technologies (such as STT-RAM, memristor, ReRAM, NVDIMM), with highly variable characteristics, will be commercially shipped as PMEM in the near future. Current evaluation studies fail to understand and categorize the idiosyncratic behavior of PMEM; i.e., how do the peculiarities of DCPMM related to other classes of PMEM. Clearly, there is a need for a study which can guide the design of systems and is agnostic to PMEM technology and internal architecture. In this paper, we first list and categorize the idiosyncratic behavior of PMEM by performing targeted experiments with our proposed PMIdioBench benchmark suite on a real DCPMM platform. Next, we conduct detailed studies to guide the design of storage systems, considering generic PMEM characteristics. The first study guides data placement on NUMA systems with PMEM while the second study guides the design of lock-free data structures, for both eADR- and ADR-enabled PMEM systems. Our results are often counter-intuitive and highlight the challenges of system design with PMEM.
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Holm-Dahlin, Sonja, Martin Andreas Olsen, Mads Bertelsen, Jonas Okkels Birk, and Kim Lefmann. "Optimization of Performance, Price, and Background of Long Neutron Guides for European Spallation Source." Quantum Beam Science 3, no. 3 (July 18, 2019): 16. http://dx.doi.org/10.3390/qubs3030016.
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We describe a systematic approach for the design of long, ballistic cold, and thermal neutron guides for the European Spallation Source (ESS). The guides investigated in this work are 170 m long and are required to have a narrowing point with room for a pulse shaping chopper placed 6 m from the moderator. In addition, most guides avoid line-of-sight from the moderator to the sample. The guides are optimized in order to find a reasonable trade-off between neutronics performance and construction price. The geometries simulated are closely related to the thermal-neutron multi-length-scale diffractometer HEIMDAL and the cold-neutron multi-analyser spectrometer BIFROST. For the cold-neutron guide an inexpensive solution was found that maintains good transport properties, while avoiding line-of-sight. However, for the thermal-neutron guide the losses when avoiding line-of-sight are large and it seems a good choice to stay in line-of-sight, even though this will increase both the shielding costs and fast-neutron background. The results are of general relevance for the understanding of the relation between transport, background, and price of long neutron guides.
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Gormley, Michael, David Kelly, David Campbell, Yunpeng Xue, and Colin Stewart. "Building Drainage System Design for Tall Buildings: Current Limitations and Public Health Implications." Buildings 11, no. 2 (February 16, 2021): 70. http://dx.doi.org/10.3390/buildings11020070.
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National design guides provide essential guidance for the design of building drainage systems, which primarily ensure the basic objectives of preventing odor ingress and cross-transmission of disease through water-trap seal retention. Current building drainage system design guides only extend to buildings of 30 floors, while modern tall buildings frequently extend to over 100 floors, exceeding the predictive capability of current design guides in terms of operating system conditions. However, the same design guides are being used for tall buildings as would be used for low-rise buildings. A complicating factor is the historic roots of current design guides and standards (including the interpretation of the governing fluid mechanics principles and margins of safety), causing many design differences to exist for the same conditions internationally, such as minimum trap seal retention requirements, stack-to-vent cross-vent spacing, and even stack diameter. The design guides also differ in the size and scale of the systems they cover, and most make no allowance for the specific building drainage system requirements of tall buildings. This paper assesses the limitations of applying current building drainage system design guides when applied to the case of tall buildings. Primarily, the assessments used in this research are based on codes from Europe, the USA and Australia/New Zealand as representative of the most common approaches and from which many other codes and standards are derived. The numerical simulation model, AIRNET, was used as the analysis tool. Our findings confirm that current design guides, which have been out of date for a number of decades, are now in urgent need of updating as code-compliant systems have been shown to be susceptible to water-trap seal depletion, a risk to cross-transmission of disease, which is a major public health concern, particularly in view of the current COVID-19 pandemic.
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Song, Xianchun, Hongjian Chen, Hongkui Jiang, Xiangrong Xu, Yanfeng Li, and Yingshang Zhang. "Improved design of roller linear guide for heavy load based on finite element method and measurement." Advances in Mechanical Engineering 10, no. 9 (September 2018): 168781401880015. http://dx.doi.org/10.1177/1687814018800158.
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Roller linear guides are key components in machine tool. The accuracy and efficiency of a machine toll are determined by the stiffness and friction torque of roller guide. This study proposes an improved design method for roller guide. The influences of the rollers profile on stiffness, stress distribution of roller linear guide are analyzed using finite element simulation. In this work, the design of the roller, slider, and the overall structure is modified. Moreover, experimental investigations on noise and sliding friction of roller linear guide are compared to validate the proposed design method. It seems that the proposed design can improve the dynamical performance of the roller linear guide.
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Carfagni, Monica, Flavio Facchini, Rocco Furferi, Marco Ghionzoli, Lapo Governi, Antonio Messineo, Francesca Uccheddu, and Yary Volpe. "Towards a CAD-based automatic procedure for patient specific cutting guides to assist sternal osteotomies in pectus arcuatum surgical correction." Journal of Computational Design and Engineering 6, no. 1 (January 3, 2018): 118–27. http://dx.doi.org/10.1016/j.jcde.2018.01.001.
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Abstract Pectus Arcuatum, a rare congenital chest wall deformity, is characterized by the protrusion and early ossification of sternal angle thus configuring as a mixed form of excavatum and carinatum features. Surgical correction of pectus arcuatum always includes one or more horizontal sternal osteotomies, consisting in performing a V-shaped horizontal cutting of the sternum (resection prism) by means of an oscillating power saw. The angle between the saw and the sternal body in the V-shaped cut is determined according to the peculiarity of the specific sternal arch. The choice of the right angle, decided by the surgeon on the basis of her/his experience, is crucial for a successful intervention. The availability of a patient-specific surgical guide conveying the correct cutting angles can considerably improve the chances of success and, at the same time, reduce the intervention time. The present paper aims to propose a new CAD-based approach to design and produce custom-made surgical guides, manufactured by using additive manufacturing techniques, to assist the sternal osteotomy. Starting from CT images, the procedure allows to determine correct resection prism and to shape the surgical guide accordingly taking into account additive manufacturing capabilities. Virtually tested against three case studies the procedure demonstrated its effectiveness. Highlights Patient-specific surgical guide improves the chances of success in sternal osteotomy. A CAD-based approach to design and produce custom-made surgical guides is proposed. The proposed framework entails both a series of automatic and user-guided tasks.
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Lubis, Pierre Yohanes. "Design Language in Motorcycle Design." Artika 4, no. 1 (September 20, 2019): 17–29. http://dx.doi.org/10.34148/artika.v4i1.165.
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Design language as a form of non-verbal communication is comprised of shapes, colour, texture, pattern, etc. These elements of design language are the penultimate way of communication for designers, especially industrial and product designers. It is the cue that guides the consumer on how to navigate and behave with a product. In relation with motorcycle design, the author investigated on the design language of various motorcycle designs, including how different types of motorcycles for different use could significantly alter the whole design language. This research was carried out with the elements of design language in mind in order to understand it a little further and how it can assist the design process.
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Sheldon, Jeffrey P., and Paul J. Lutkevich. "Light Guides for Tunnels." Transportation Research Record: Journal of the Transportation Research Board 1553, no. 1 (January 1996): 81–85. http://dx.doi.org/10.1177/0361198196155300112.
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The use of light guides has been limited to accent or specialty lighting and generally has been considered impractical for large-scale applications. After careful study, 2 mi of light guides were installed in Boston's Callahan Tunnel. The 2-year study and design process is reviewed, and the system's performance after a year of operation is assessed.
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Calvo-Villamañán, Alicia, Jérome Wong Ng, Rémi Planel, Hervé Ménager, Arthur Chen, Lun Cui, and David Bikard. "On-target activity predictions enable improved CRISPR–dCas9 screens in bacteria." Nucleic Acids Research 48, no. 11 (April 30, 2020): e64-e64. http://dx.doi.org/10.1093/nar/gkaa294.
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Abstract The ability to block gene expression in bacteria with the catalytically inactive mutant of Cas9, known as dCas9, is quickly becoming a standard methodology to probe gene function, perform high-throughput screens, and engineer cells for desired purposes. Yet, we still lack a good understanding of the design rules that determine on-target activity for dCas9. Taking advantage of high-throughput screening data, we fit a model to predict the ability of dCas9 to block the RNA polymerase based on the target sequence, and validate its performance on independently generated datasets. We further design a novel genome wide guide RNA library for E. coli MG1655, EcoWG1, using our model to choose guides with high activity while avoiding guides which might be toxic or have off-target effects. A screen performed using the EcoWG1 library during growth in rich medium improved upon previously published screens, demonstrating that very good performances can be attained using only a small number of well designed guides. Being able to design effective, smaller libraries will help make CRISPRi screens even easier to perform and more cost-effective. Our model and materials are available to the community through crispr.pasteur.fr and Addgene.
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Rankin, Iain, Haroon Rehman, and Mark Frame. "3D-Printed Patient-Specific ACL Femoral Tunnel Guide from MRI." Open Orthopaedics Journal 12, no. 1 (February 28, 2018): 59–68. http://dx.doi.org/10.2174/1874325001812010059.
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Background: Traditional ACL reconstruction with non-anatomic techniques can demonstrate unsatisfactory long-term outcomes with regards instability and the degenerative knee changes observed with these results. Anatomic ACL reconstruction attempts to closely reproduce the patient's individual anatomic characteristics with the aim of restoring knee kinematics, in order to improve patient short and long-term outcomes. We designed an arthroscopic, patient-specific, ACL femoral tunnel guide to aid anatomical placement of the ACL graft within the femoral tunnel. Methods: The guide design was based on MRI scan of the subject's uninjured contralateral knee, identifying the femoral footprint and its anatomical position relative to the borders of the femoral articular cartilage. Image processing software was used to create a 3D computer aided design which was subsequently exported to a 3D-printing service. Results: Transparent acrylic based photopolymer, PA220 plastic and 316L stainless steel patient-specific ACL femoral tunnel guides were created; the models produced were accurate with no statistical difference in size and positioning of the center of the ACL femoral footprint guide to MRI (p=0.344, p=0.189, p=0.233 respectively). The guides aim to provide accurate marking of the starting point of the femoral tunnel in arthroscopic ACL reconstruction. Conclusion: This study serves as a proof of concept for the accurate creation of 3D-printed patient-specific guides for the anatomical placement of the femoral tunnel during ACL reconstruction.
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Coachman, Francis, Gustavo Petrili, Guilherme José Pimentel Lopes de Oliveira, Bruna Ghiraldini, and Fábio José Barbosa Bezerra. "The DSD clicGuide system: a new concept for full-arch implant placement and immediate loading rehabilitation using the digital workflow: a clinical report of three cases." Revista Odontológica do Brasil Central 30, no. 89 (February 6, 2021): 20–32. http://dx.doi.org/10.36065/robrac.v30i89.1432.
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One of the limitations of using guided surgery for full arch rehabilitation is related to the cases where it is necessary to perform osteotomy prior to the placement of the implant. The Digital Smile Design ClicGuide (DSD ClicGuide) is a digital rehabilitation planning system recommended in the rehabilitation of fully edentulous jaws, which orients implant placement procedures and immediate provisional loading based on an ideal three-dimensional design. This system consists of a sequence of surgical guides used during the clinical procedures that may include teeth extractions, osteotomies, implant placements, and immediate prothesis installation, increasing the level of predictability of rehabilitation procedures in these complex clinical cases. The aim of this case series report is to describe the oral rehabilitation of three patients treated according to the DSD ClicGuide technique, who received a total of twenty dental implants. All the patients treated required total oral rehabilitation in at least one of the arches and required osteotomies in order to regularize the alveolar ridge before the placement of the implant. Once the rehabilitation parameters were defined and the treatment plan was approved, the following guides were printed and used in sequence: a base guide that was used as a reference for the osteotomy procedure; a guide for installing the implants; and a guide with the printed temporary prosthesis for immediate loading. It can be conclude that the DSD ClicGuide system enabled the osteotomy, implants placement, and installation of an immediate loading prosthesis in totally edentulous patients, with a high level of predictability.
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MBATHA, Fisokuhle, Vyasha HARILAL, and Tembi Maloney TICHAAWA. "TOURIST GUIDES, COVID 19 AND SURVIVAL MECHANISMS IN SOUTH AFRICA." GeoJournal of Tourism and Geosites 39, no. 4 supplement (December 31, 2021): 1461–72. http://dx.doi.org/10.30892/gtg.394spl17-790.
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The main aim of this research was to investigate the survival mechanisms employed by tourist guides in the context of the Covid 19 Pandemic. A mixed method research design was adopted, using in-depth interviews with key tourism informants and surveys administered to tourist guides in Gauteng. A total of five key informant interviews and two hundred surveys were collected at the end of the data collection period. Key findings indicate that many tourist guides were unable to access the aforementioned fund and had to implement their own short and long-term survival mechanisms. In many cases, various cost cutting measures were implemented and the utilization of personal savings and loans. Other guides temporarily engaged in different employment to secure an income. This study presents policy and systemic recommendations, which, if accepted and implemented, could assist the reignition of the tourist guide profession post-pandemic and ensure they form part of the tourism sector recovery trajectory. Additionally, further research on tourist guides in South Africa needs to be conducted, to fully understand the various aspects of this profession in the country.
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Maribbay, Agripina B. "Enhancing the Delivery of the Teacher Education Courses through the Development of OBE-Based Teaching Guides." World Journal of Educational Research 8, no. 1 (December 19, 2020): p36. http://dx.doi.org/10.22158/wjer.v8n1p36.
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This project aimed to develop Outcomes-Based Education (OBE) teaching guides to enhance the delivery of courses in the teacher education programs. This paper specifically provides the result of the participants’ assessment and problems encountered in the implementation of the OBE-based approach in teaching. The 200 study participants covered faculty and administrators of thirty (30) selected Teacher Education Institutions in Region 02. Results reveal that the OBE-based approach was implemented to a great extent along Institutional Mission, moderate extent in terms of outcomes and low extent along areas such as curriculum, instructional delivery, assessment, and reporting. Participants’ inadequacy of knowledge and skills, teaching resources, and time were among the problems encountered by the participants in the implementation of the OBE-approach in the teacher education curriculum. These results serve as a guide for the development of OBE-based teaching guides to enhance the implementation of the curriculum. The development of the teaching guides was based on a set of frameworks. The Project Proposal Framework particularly details the processes undertaken in the development of the teaching guides while the SPUP-OBE Framework provides the teaching guides’ content. Furthermore, it presents the specific methods for the teachers’ training on the principles and standards of OBE, the development of OBE-based teaching guides, the logical framework of the proposed teaching guide, the monitoring and evaluation plan, and the dissemination plan. This method includes the design, scope, tools, and analytical procedures for the specific processes involved.
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Kim, Nam Wook, Eston Schweickart, Zhicheng Liu, Mira Dontcheva, Wilmot Li, Jovan Popovic, and Hanspeter Pfister. "Data-Driven Guides: Supporting Expressive Design for Information Graphics." IEEE Transactions on Visualization and Computer Graphics 23, no. 1 (January 2017): 491–500. http://dx.doi.org/10.1109/tvcg.2016.2598620.
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Watton, J. "Optimum response design guides for electrohydraulic cylinder control systems." Applied Mathematical Modelling 14, no. 11 (November 1990): 598–604. http://dx.doi.org/10.1016/0307-904x(90)90109-i.
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Hussein, Mohamed, Tarek Sayed, Karim Ismail, and Adinda Van Espen. "Calibrating Road Design Guides Using Risk-Based Reliability Analysis." Journal of Transportation Engineering 140, no. 9 (September 2014): 04014041. http://dx.doi.org/10.1061/(asce)te.1943-5436.0000694.
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