Relevant bibliographies by topics / Design agents

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Design agents'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

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Journal articles on the topic "Design agents"

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Grecu, Dan L., and David C. Brown. "Design agents that learn." Artificial Intelligence for Engineering Design, Analysis and Manufacturing 10, no. 2 (April 1996): 149–50. http://dx.doi.org/10.1017/s0890060400001426.

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This research originates in the work started several years ago at Worcester Polytechnic Institute dedicated to the investigation, modelling and evaluation of multiagent based design. The main thrust behind our approach is the idea of finding elementary patterns of agent problem-solving and interaction in design tasks. To achieve this goal we introduced and defined the concept of Single Function Agents, (SiFAs) (Dunskus, 1995; SiFA, 1995). SiFAs are agents specialized to perform one single generic function during the design process. Some typical functions would be selection, evaluation, and critique. These types of agents can be instantiated for different, particular design domains.
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Gorbunov, Roman, Emilia Barakova, and Matthias Rauterberg. "Design of social agents." Neurocomputing 114 (August 2013): 92–97. http://dx.doi.org/10.1016/j.neucom.2012.06.046.

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McKinlay, M. A., and M. G. Rossmann. "Rational Design of Antiviral Agents." Annual Review of Pharmacology and Toxicology 29, no. 1 (April 1989): 111–22. http://dx.doi.org/10.1146/annurev.pa.29.040189.000551.

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Kubo, Isao, Ping Xiao, Ken-ichi Nihei, Ken-ichi Fujita, Yoshiro Yamagiwa, and Tadao Kamikawa. "Molecular Design of Antifungal Agents." Journal of Agricultural and Food Chemistry 50, no. 14 (July 2002): 3992–98. http://dx.doi.org/10.1021/jf020088v.

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Hider, R. C. "Design of therapeutic chelating agents." Biochemical Society Transactions 30, no. 4 (August 1, 2002): 751–55. http://dx.doi.org/10.1042/bst0300751.

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The successful design of orally active non-toxic selective metal chelators is a much sought-after goal. In order to identify an ideal chelator for clinical use, a range of specifications must be considered, such as metal selectivity and affinity, kinetic stability of the complex, bioavailability and toxicity. In this overview the comparative properties of ligands capable of endowing complexes with such properties will be discussed.
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Kubo, Isao, Ikuyo Kinst-Hori, Yumi Kubo, Yoshiro Yamagiwa, Tadao Kamikawa, and Hiroyuki Haraguchi. "Molecular Design of Antibrowning Agents†." Journal of Agricultural and Food Chemistry 48, no. 4 (April 2000): 1393–99. http://dx.doi.org/10.1021/jf990926u.

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Tan, Antoinette R., and Sandra M. Swain. "Novel agents: Clinical trial design." Seminars in Oncology 28, no. 5N (October 2001): 148–53. http://dx.doi.org/10.1053/sonc.2001.28556.

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Montgomery, John A. "The design of chemotherapeutic agents." Accounts of Chemical Research 19, no. 10 (October 1986): 293–300. http://dx.doi.org/10.1021/ar00130a001.

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Gero, John S., and Gregory J. Smith. "Context, situations, and design agents." Knowledge-Based Systems 22, no. 8 (December 2009): 600–609. http://dx.doi.org/10.1016/j.knosys.2009.05.005.

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TAN, A. "Novel agents: Clinical trial design." Seminars in Oncology 28 (October 2001): 148–53. http://dx.doi.org/10.1016/s0093-7754(01)90292-1.

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Dissertations / Theses on the topic "Design agents"

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Gu, Ning. "Dynamic Designs of Virtual Worlds Using Generative Design Agents." Thesis, The University of Sydney, 2006. http://hdl.handle.net/2123/984.

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This research aims at developing a different kind of virtual world that is dynamically designed and implemented as needed. Currently, most virtual world designs are considered static. Similar to the physical world, these worlds are pre-defined prior to their use. The resultant environments serve certain purposes but do not take into consideration possible changes to the purposes during their use, changes which often occur when the occupants interact with the environments and with each other. Virtual worlds as networked environments can be flexibly configured and programmed. This flexibility makes it possible to consider virtual world designs in terms of dynamics and autonomy, reflecting the changing needs of different moments. To achieve dynamic designs of virtual worlds, this study applies a computational approach using rational design agents. A Generative Design Agent (GDA) model is developed that specifies computational processes for reasoning and designing in virtual worlds. The GDAs serve as personal design agents to the virtual world occupants. Design formalisms for virtual worlds are also addressed. The design component of a GDA is supported by the application of a generative design grammar. On one hand, generative design grammars serve as the generative force to be applied by the GDAs for virtual world design automation. On the other hand, each grammar defines coherent stylistic characterisations shared by the virtual world designs it generates. The technical outcomes of the research consist of the GDA model and a generative design grammar framework. The framework provides guidelines and strategies to designers for developing generative design grammars that produce different design languages for virtual worlds, rather than predefine every detail of all possible virtual world designs. GDAs monitor the virtual worlds and the various activities that occur in the worlds, interpret the occupants’ needs in the virtual worlds and the state of the worlds based on these observations, hypothesise design goals in order to satisfy these needs, and finally apply generative design grammars to provide virtual world designs for the moment, or initiate other actions in the worlds, according to the current design goals, on behalf of the occupants. The development of the GDA model and the generative design grammar framework provides new perspectives for understanding and developing virtual worlds. The GDA model challenges the conventional way that virtual worlds are designed and implemented, and this leads to dynamic designs of virtual worlds. The generative design grammar framework provides a computational approach to formally defining design languages for virtual worlds.
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Gu, Ning. "Dynamic Designs of Virtual Worlds Using Generative Design Agents." Architecture, 2006. http://hdl.handle.net/2123/984.

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Doctor of Philosophy (PhD)
This research aims at developing a different kind of virtual world that is dynamically designed and implemented as needed. Currently, most virtual world designs are considered static. Similar to the physical world, these worlds are pre-defined prior to their use. The resultant environments serve certain purposes but do not take into consideration possible changes to the purposes during their use, changes which often occur when the occupants interact with the environments and with each other. Virtual worlds as networked environments can be flexibly configured and programmed. This flexibility makes it possible to consider virtual world designs in terms of dynamics and autonomy, reflecting the changing needs of different moments. To achieve dynamic designs of virtual worlds, this study applies a computational approach using rational design agents. A Generative Design Agent (GDA) model is developed that specifies computational processes for reasoning and designing in virtual worlds. The GDAs serve as personal design agents to the virtual world occupants. Design formalisms for virtual worlds are also addressed. The design component of a GDA is supported by the application of a generative design grammar. On one hand, generative design grammars serve as the generative force to be applied by the GDAs for virtual world design automation. On the other hand, each grammar defines coherent stylistic characterisations shared by the virtual world designs it generates. The technical outcomes of the research consist of the GDA model and a generative design grammar framework. The framework provides guidelines and strategies to designers for developing generative design grammars that produce different design languages for virtual worlds, rather than predefine every detail of all possible virtual world designs. GDAs monitor the virtual worlds and the various activities that occur in the worlds, interpret the occupants’ needs in the virtual worlds and the state of the worlds based on these observations, hypothesise design goals in order to satisfy these needs, and finally apply generative design grammars to provide virtual world designs for the moment, or initiate other actions in the worlds, according to the current design goals, on behalf of the occupants. The development of the GDA model and the generative design grammar framework provides new perspectives for understanding and developing virtual worlds. The GDA model challenges the conventional way that virtual worlds are designed and implemented, and this leads to dynamic designs of virtual worlds. The generative design grammar framework provides a computational approach to formally defining design languages for virtual worlds.
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Redij, Tejashree. "Rational Design of Anti-diabetic Agents." Thesis, University of the Sciences in Philadelphia, 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=13861629.

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The Glucagon-like peptide 1 receptor (GLP-1R) belongs to the pharmaceutically important Class B family of G-protein coupled receptors (GPCRs) and its incretin peptide ligand GLP-1 analogs are adopted drugs for the treatment of type 2 diabetes (T2D). Despite remarkable anti-diabetic effects, Glucagon Like Peptide-1 (GLP-1) peptide-based drugs are limited by the need of injection or high cost oral formulation. On the other hand, developing non-peptide small molecule drugs targeting GLP-1R remains elusive likely due to the large nature of the orthosteric binding site on GLP-1R. A promising approach is to develop small molecule agonistic positive allosteric modulators (ago-PAMs) or positive allosteric modulators (PAMs) of GLP-1R by targeting the potential allosteric sites in the transmembrane (TM) domain of human GLP-1R.

As the first step of taking this approach, we constructed a three-dimensional structure model of the TM domain of human GLP-1R using homology modeling and conformational sampling techniques. Next, a potential allosteric binding site on the TM domain was predicted computationally. In silico screening of drug-like compounds against this predicted allosteric site has identified nine compounds as potential GLP-1R agonists. The independent agonistic activity of two compounds was subsequently confirmed using cyclic adenosine monophosphate (cAMP) response element (CRE)-based luciferase reporting system. One compound was also shown to stimulate insulin secretion through in vitro assay. In addition, this compound synergized with GLP-1 to activate human GLP-1R.

In 2017, the crystal structures of GLP-1R in its active state (PDB ID: 5VAI) became available. Hence, we have performed another round of in silico screening employing this structure. First, the potential ligand binding sites in 5VAI were identified using computational tools and in silico screening procedure as described above was carried out again. A new small 8 molecule with low molecular weight and logP was identified. In vitro studies of this compound confirmed that it acts as the ago-Positive Allosteric Modulator (PAM) of GLP-1R that improves GLP-1's affinity and efficacy towards GLP-1R. When used in combination with GLP-1, this compound improves insulin secretion than using GLP-1 alone. Site specific mutagenesis studies confirmed its binding site as predicted in the TM domain of GLP-1R.

Finally, this ago-PAM molecule was further optimized to improve its potency and specificity towards GLP-1R using structure-based optimization strategy and medicinal synthesis. The newly designed compound, whose molecular weight was less than the parental compound, was found to act as the PAM of GLP-1R and showed improvement in the specificity than the parental compound. Thus, this new compound could be further exploited in the drug development for T2D treatment.

These results demonstrated that allosteric regulation exists in GLP-1R and can be exploited for developing small molecule agonists. The success of this work will help pave the way for small molecule drug discovery targeting other Class B GPCRs through allosteric regulations.

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Zrehen, Stéphane. "Elements of brain design for autonomous agents /." [S.l.] : [s.n.], 1995. http://library.epfl.ch/theses/?nr=1373.

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Okamoto, Masayuki. "Design and applications of learning conversational agents." 京都大学 (Kyoto University), 2003. http://hdl.handle.net/2433/148780.

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Arnold, Stephen John. "The design of agents against alzheimer's disease." Thesis, Open University, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536076.

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Khristova, Tetiana. "Computer-aided design of novel antithrombotic agents." Phd thesis, Université de Strasbourg, 2013. http://tel.archives-ouvertes.fr/tel-01018545.

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Thrombosis is the most important pathological process underlying many cardiovascular diseases, which are responsible for high mortality worldwide. In this theses the computer-aided design of new anti-thrombotic agents able to inhibit two types of receptors located on the surface of the platelets has been applied. The first one - αIIbβ3 - is responsible for the interaction of activated platelets with fibrinogen to form clots, whereas the second one - thromboxane A2 - is responsible for platelet activation by one of agonists excreted by activated platelets. To achieve this, different types of models have been developed using experimentally available information and structure of protein-ligand complexes. This concerns: QSAR models, structure-based and ligand-based 3D pharmacophore models, 2D pharmacophore models, shape-based and molecular field-based models. The ensemble of the developed models were used in virtual screening. This study resulted in suggestion of new potential antagonists of αIIbβ3 and thromboxane A2 receptors. Suggested antagonists of αIIbβ3 able to bind either open or closed form of the receptor have been synthesized and tested experimentally. Experiments show that they display high activity; moreover some of theoretically designed compounds are more efficient than Tirofiban - the commercialized drug molecule. The recommended antagonists of thromboxane A2 receptor have been already synthesized but biological tests have not been completed yet.
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De, Jager Josephus Jacobus. "Design and synthesis of novel antimalarial agents." Thesis, Stellenbosh : Stellenbosh University, 2014. http://hdl.handle.net/10019.1/96071.

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Thesis (MSc)--Stellenbosch University, 2014.
ENGLISH ABSTRACT: Malaria is a pestilent disease associated with massive socioeconomic burden of sub-Saharan Africa. This disease is caused by a blood infection of the single cellular parasite of the Plasmodium genus. Two enzymes of this parasite have been identified to be essential to the survival of this parasite, notably Spermidine Synthase and Protein Farnesyltransferase. The goal of this dissertation was to search for and synthesise novel inhibitors of these two enzymes with a strong focus towards understanding their structure/activity relationships. To achieve the first goal, molecular modelling was employed. An in-depth discussion is presented to describe the underlying principles relevant to this branch of computational chemistry. This ensures that the experiments using these methods are set-up correctly and results are interpreted within context. Two virtual high-throughput screens were then performed using prepared crystallographic structures of Spermidine Synthase. The first was pharmacophore based method and the second based on LibDock. The database used, containing 7.1 million compounds, was filtered using a custom developed tool prior to screening. Finally, CDOCKER was then used to investigate the activity of potential hit compounds. Spermidine Synthase has a natural affinity for adenosine and this trait was exploited by derivatising analogues to synthesise potential inhibitors of the enzyme. This was to be achieved by the incorporation of both electrophilic and nucleophilic moieties at selected positions, including the use of a high yielding Mitsunobu reaction. A number of additional residues were then synthesised and joined to the adenosine which were proposed to increase the active site occupancy and increase affinity to the enzyme. For the second enzyme targeted for inhibition, Protein Farnesyltransferase, indole was used as a starting scaffold to synthesise potential hits de novo. It was aimed to derivatise the indole at the Nʹ and 3ʹ positions. The crystal structure of one of the intermediates was published. Furthermore, a synthetic sequence which culminated in a palladium catalysed Suzuki coupling was performed.
AFRIKAANSE OPSOMMING: Malaria is ‘n peslike siekte wat geassosieer word met beduinde sosio-ekonomiese implikasies vir sub-Sahara Afrika. Die siekte word veroorsaak deur ‘n bloed infeksie van die enkel sellulêre parasiet van die Plasmodium genus. Twee ensieme, naamlik Spermidien Sintetase en Protein Farnesieltransferase, is geïdentifiseer om noodsaaklik te wees vir die oorlewing van die parasiet. Die doelwit van hierdie verhandeling is die soektog en sintese van oorspronklike inhibeerders van hierdie twee ensieme met ‘n sterk fokus daarop om struktuur/aktiwiteit interaksies te verstaan. Om die eerste doelwit te bereik is molekulêre modellering toegepas. ‘n Indiepte ondersoek word voorgestel om die onderliggende beginsels relevant tot hierdie tak van berekenkundige chemie te beskryf. Dit verseker dat eksperimente wat op hierdie tegnieke berus korrek opgestel word en dat die resultate binne konteks geïnterpreteer word. Twee virtuele hoë-deurset skerms was deurgevoer op voorbereide kristallografiese strukture van Spermidien Sintetase. Die eerste het berus op ‘n pharmakoforiese metode en die tweede op LibDock. ‘n Self-ontwikkelde sagteware gereedskap stuk is gebruik om a databasis van 7.1 miljoen verbindings te filtreer voor dit gebruik is in hoë-deurset skerms. Uiteindelik is CDOCKER gebruik om die potensiele aktiwiteit van “treffer” verbindings te beraam. Spermidien syntetase het ‘n natuurlike affiniteit vir adenosien en hierdie eienskap is benut deur analoeë af te lei na potensiële inhibeerders teen die ensiem. Dit is bewerkstellig deur die insluiting van beide elektrofiliese asook nukleifielese funksionele groepe op gekose posisies. Dit het die gebruik van ‘n hoë opbrengs Mitsunobu reaksie ingesluit. ‘n Aantal ander addisionele residueë is toe gesintetiseer en geheg aan die afgeleide adenosien om die ensiem setel te vul en sodoende die affinitieit te verhoog. Vir die tweede ensiem wat geteiken is vir inhibisie, Protein Farnesieltransferase, is indool benuttig as ‘n begin steier te dien om potensiële treffers de novo te sintetiseer. Dit is geteiken om die indool af te lei op die Nʹ en 3ʹ posisies en die kristal struktuur van een van hierdie tussengangers is gepubliseer. Verder is ‘n sintetiese weg, wat uitgeloop het op ‘n palladium gekataliseerde Suzuki koppeling, uitgevoer.
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Williams, Jarrod C. "Design and Synthesis of Superresolution Imaging Agents." Kent State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=kent1342887517.

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Zhang, Weihe. "Design and Synthesis of Potential Anticancer Agents." Ohio University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1288896777.

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Books on the topic "Design agents"

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Müller, Jörg P. The Design of Intelligent Agents. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/bfb0017806.

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Zhang, Chengqi, and Von-Wun Soo, eds. Design and Applications of Intelligent Agents. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/3-540-44594-3.

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1945-, Pettit Philip, ed. Group agency: The possibility, design, and status of corporate agents. Oxford: Oxford University Press, 2011.

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Karsa, D. R. Design and selection of performance surfactants. Sheffield, England: Sheffield Academic Press, 1999.

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P, Müller J. The design of intelligent agents: A layered approach. Berlin: Springer, 1996.

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S, Borer J., and Somberg John C, eds. Cardiovascular drug development: Protocol design and methodology. New York: M. Dekker, 1999.

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Gad, Shayne C. Development of therapeutic agents handbook. Hoboken, NJ: John Wiley & Sons, 2011.

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Sharma, Satyavan. Approaches to design and synthesis of antiparasitic drugs. Amsterdam: Elsevier, 1997.

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1977-, Ichalkaranje Nikhil, and Jain L. C, eds. Design of intelligent multi-agent systems: Human-centredness, architectures, learning, and adaptation. Berlin: Springer, 2004.

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Dabberdt, Walter F. Conceptual design for a Gulf Coast oxidant transport and transformation experiment: Workshop proceedings and recommendations. Research Triangle Park, NC: U.S. Environmental Protection Agency, Atmospheric Sciences Research Laboratory, 1985.

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Book chapters on the topic "Design agents"

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Aridor, Yariv, and Mitsuru Oshima. "Infrastructure for mobile agents: Requirements and design." In Mobile Agents, 38–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/bfb0057647.

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Gorbunov, Roman, Emilia Barakova, and Matthias Rauterberg. "Design of Social Agents." In Lecture Notes in Computer Science, 192–201. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-21344-1_21.

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Smith, Gregory J., and John S. Gero. "Describing Situated Design Agents." In Design Computing and Cognition ’04, 439–57. Dordrecht: Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2393-4_23.

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Park, Gi-Duck, Robert McCartney, and Jung-Jin Yang. "The Design of a Self-locating Automatic-Driving Robot." In Intelligent Agents and Multi-Agent Systems, 323–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-89674-6_36.

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Lee, Jimmy H. M., and Lei Zhao. "A Real-Time Agent Architecture: Design, Implementation and Evaluation." In Intelligent Agents and Multi-Agent Systems, 18–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/3-540-45680-5_2.

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Bonnet, Célia S., and Éva Tóth. "MRI Contrast Agents." In Ligand Design in Medicinal Inorganic Chemistry, 321–54. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118697191.ch12.

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Regayeg, Amira, Ahmed Hadj Kacem, and Mohamed Jmaiel. "Specification and Design of Multi-agent Applications Using Temporal Z." In Intelligent Agents and Multi-Agent Systems, 228–42. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/978-3-540-32128-6_18.

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Jonell, Patrik, Catharine Oertel, Dimosthenis Kontogiorgos, Jonas Beskow, and Joakim Gustafson. "Crowd-Powered Design of Virtual Attentive Listeners." In Intelligent Virtual Agents, 188–91. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-67401-8_21.

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Mumme, Christopher, Niels Pinkwart, and Frank Loll. "Design and Implementation of a Virtual Salesclerk." In Intelligent Virtual Agents, 379–85. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-04380-2_41.

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Bryson, Joanna, and Brendan McGonigle. "Agent architecture as object oriented design." In Intelligent Agents IV Agent Theories, Architectures, and Languages, 15–29. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/bfb0026747.

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Conference papers on the topic "Design agents"

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Barber, K. S., R. M. McKay, C. E. Martin, T. H. Liu, J. Kim, D. Han, and A. Goel. "Sensible Agents in Supply Chain Management: An Example Highlighting Procurement and Production Decisions." In ASME 1999 Design Engineering Technical Conferences. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/detc99/cie-9078.

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Abstract Agent-based technologies can be applied to many aspects of supply chain management. The need for responsive, flexible agents is pervasive in this environment due to its complex, dynamic nature. Two critical aspects of agent capabilities are the ability to (1) classify agent behaviors according to autonomy level and (2) adapt problem-solving roles to various problem-solving situations during system operation. Sensible Agents, capable of Dynamic Adaptive Autonomy, have been developed to address these issues. A Sensible Agent’s “autonomy level” constitutes a description of the agent’s problem-solving role with respect to a particular goal. Problem-solving roles are defined along a spectrum of autonomy ranging from command-driven, to consensus, to locally autonomous/master. Dynamic Adaptive Autonomy is a capability that allows Sensible Agents to change autonomy levels during system operation to meet the needs of a particular problem-solving situation. This paper provides an overview of the Sensible Agent Testbed and introduces an example supply chain management domain with a scenario showing how this testbed could be used to simulate agent-based problem solving.
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Skolicki, Zbigniew, and Tomasz Arciszewski. "Intelligent Agents in Design." In ASME 2003 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/detc2003/dtm-48671.

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In this paper we argue that learning or adaptation ability should be included in the basic set of features characterizing an intelligent agent in design. We propose a collection of attributes describing agents, which are grouped into several categories. Next, we present the results of a detailed study of all agents for design, which were discussed during the First International Workshop on Agents in Design at MIT in August of 2002. A statistical analysis of their attributes has been conducted and its results are reported to suggest future evolution of agents in design. Finally, we briefly overview the topic of Directed Evolution and use its paradigms to predict further development of agents in design. The paper also provides our initial conclusions and suggests further research.
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Miyashita, Tomoyuki, and Hiroshi Yamakawa. "Optimum Design Using Search Agents." In ASME 2001 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/detc2001/dac-21011.

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Abstract Many optimization methods and practical softwares have been developing for many years and most of them are very effective, especially to solve practical problems. But, non-linearity of objective functions and constraint functions, which have frequently seen in practical problems, has caused a difficulty in optimization. This difficulty mainly lies in the existence of several local optimum solutions. In this study, we have proposed a new global optimization methodology that provides an information exchange mechanism in the nearest neighbor method. We have developed a simple software system, which treated each design point in optimization as an agent. Many agents can search the optima simultaneously exchanging the their information. We have defined two roles of the agents. Local search agents have roles on searching local optima by such an existing method as the steepest decent method and so on. Stochastic search agents investigate the design space by making use of the information from other agents. Through simple and several structural optimization problems, we have confirmed the advantages of the method.
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"Agents and multi-agent systems." In 8th International Conference on Computer Supported Cooperative Work in Design. IEEE, 2004. http://dx.doi.org/10.1109/cacwd.2004.1349032.

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Jha, Krishna N., Andrea Morris, Ed Mytych, and Judith Spering. "Agent Support for Collaborative Design." In ASME 1998 Design Engineering Technical Conferences. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/detc98/cie-5551.

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Abstract Extensive collaboration among multiple distributed design groups is required to design aircraft parts. Achieving such a collaboration manually is time-consuming, expensive, and inefficient; but the cost of ignoring or minimizing it is much higher in terms of delayed and/or inferior quality products. We describe a multi-agent-based approach to support the desired collaboration among the design groups during the preliminary design (PD) process. A variety of agents including interface agents and control agents are used to model the various collaboration functionalities. The agent-representation includes a formal representation of the task-structures. A web-based user-interface provides high-level interface to the users. The agents collaborate to produce optimized and feasible designs.
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Wang, Shilong, Jian Yi, Xia Hong, and Z. Zhang. "Heterogeneous Autonomous Agent Architecture for Agile Manufacturing." In ASME 2002 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2002. http://dx.doi.org/10.1115/detc2002/cie-34397.

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Considering the agent-based modeling and mapping in manufacturing system, some system models are described in this paper, which are included: Domain Based Hierarchical Structure (DBHS), Cascading Agent Structure (CAS), Proximity Relation structure (PRS), and Bus-based network structure (BNS). In DBHS, one sort of agents, called static agents, individually acts as Domain Agents, Resources Agents, UserInterface Agents and Gateway Agents. And the others, named mobile agents, are the brokers of task and process flow. Static agents representing a subsystem may itself be an agent-based network and should learn as the mobile agents to deal with new situation. Mobile agents move around the network domains taking advantage of the resources to fulfill their goals. In CAS, We use Unified Modeling Language (UML) to build up the agent-based manufacturing system It is said Enterprise agent (main agent) has factory agents together with some directly jurisdictional workshop agents, cell agents, and individual resource agents. Likewise, factory agent has workshop agents together with some directly jurisdictional cell agents and individual resource agents, and so on. In PRS, the resources agents are located together by its function and abilities. There is only one agent behaves as the task-announcer. The communication just occurs among the Proximity Relational agents. In BNS, It is very similar with the society of human being connected with a network, some agents, such as ‘cost calculating’, are just cope with the matter-of-fact job. And some agents run as the individual resources that can negotiate with each other and advertise a necessary message within the whole domain or a given group of agents. The administration just relies on the individual address of agents and the group ID code of agents.
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Wu, Yuechen, Wei Zhang, and Ke Song. "Master-Slave Curriculum Design for Reinforcement Learning." In Twenty-Seventh International Joint Conference on Artificial Intelligence {IJCAI-18}. California: International Joint Conferences on Artificial Intelligence Organization, 2018. http://dx.doi.org/10.24963/ijcai.2018/211.

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Curriculum learning is often introduced as a leverage to improve the agent training for complex tasks, where the goal is to generate a sequence of easier subasks for an agent to train on, such that final performance or learning speed is improved. However, conventional curriculum is mainly designed for one agent with fixed action space and sequential simple-to-hard training manner. Instead, we present a novel curriculum learning strategy by introducing the concept of master-slave agents and enabling flexible action setting for agent training. Multiple agents, referred as master agent for the target task and slave agents for the subtasks, are trained concurrently within different action spaces by sharing a perception network with an asynchronous strategy. Extensive evaluation on the VizDoom platform demonstrates the joint learning of master agent and slave agents mutually benefit each other. Significant improvement is obtained over A3C in terms of learning speed and performance.
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Raina, Ayush, Christopher McComb, and Jonathan Cagan. "Design Strategy Transfer in Cognitively-Inspired Agents." In ASME 2018 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/detc2018-85599.

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Planning and strategizing are essential parts of the design process and are based on the designer’s skill. Further, planning is an abstract skill that can be transferred between similar problems. However, planning and strategy transfer within design have not been effectively modeled within computational agents. This paper presents an approach to represent this strategizing behavior using a probabilistic model. This model is employed to select the operations that computational agents should perform while solving configuration design tasks. This work also demonstrates that this probabilistic model can be used to transfer strategies from human data to computational agents in a way that is general and useful. This study shows a successful transfer of design strategy from human-to-computer agents, opening up the possibility of deriving high-performing behavior from designers and using it to guide computational design agents. Finally, a quintessential behavior of transfer learning is illustrated by agents while transferring design strategies across different problems, improving agent performance significantly. The work presented in this study leverages a computational framework built by embedding cognitive characteristics into agents, which has shown to mimic human problem-solving in configuration design problems.
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Sagar, Keerthi, Dimiter Zlatanov, Matteo Zoppi, Cristiano Nattero, and Sreekumar Muthuswamy. "Orientation Planning for Multi-Agents With Discrete-Step Locomotion and Multiple Goals." In ASME 2018 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/detc2018-86147.

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The paper addresses the coordinated path planning of mobile agents with multiple goal positions and orientations in a plane. The targeted multi-robot system uses discrete locomotion ensuring uncertainty-free localization and mapping as well as simple and robust control. It is suitable for material-handling, reconfigurable-fixturing, and mobile-manipulation tasks in a flexible-manufacturing environment. Using its three leg, and matching pin-socket couplings with the base surface, each agent either stands fixed or strides along via “Swing and Dock” (SaD) locomotion. Each mounting pin can serve both as a connecting-locking device and as a pivot of a planar rotation. Previous work offered planning solutions only for the agents’ positions. In reality, the orientation in which the agent arrives at the goal is very important because neither robot workspaces nor workcell geometries have axial symmetry. Herein, we provide for the required orientational planning by labelling the agent’s legs to keep track of its rotation. Integer Linear Programming (ILP) is used to model the path planning problem in the so augmented configuration space. The mathematical formulations are implemented and tested using a GUROBI solver. Computational results display the effectiveness of the approach.
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Sreeram, R. T., and P. K. Chawdhry. "A Single Function Agent Framework for Task Decomposition and Conflict Negotiation." In ASME 1998 Design Engineering Technical Conferences. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/detc98/dfm-5748.

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Abstract Researchers in agent-based concurrent engineering have identified a variety of techniques for product development with the use of multi-agents. Significant but less common are the techniques based on more task-specific single function agents. This paper proposes a single function agent framework for task-solving in a product development environment. This framework is based on Habermas’s theory of communicative action which is particularly suited for collaborative work. The inter-agent communication is based on Knowledge Query Manipulation Language (KQML). The task decomposition of the design process is based on the cluster identification algorithm. The conflicts which arise during the design process are resolved by using very specialized single function agents that detect conflicts based on violation of the design constraints. The case study on the design of a mechanical shaft demonstrates the appropriateness of the proposed framework.
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Reports on the topic "Design agents"

1

Hay, Benjamin P., and Brian M. Rapko. Computational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), June 2005. http://dx.doi.org/10.2172/893278.

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Hay, Benjamin P., and Brian M. Rapko. Computational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), June 2006. http://dx.doi.org/10.2172/895761.

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Hay, Benjamin P., and Brian M. Rapko. Computational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), June 2005. http://dx.doi.org/10.2172/885060.

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Hay, Benjamin P., David A. Dixon, and Brian M. Rapko. Computational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), June 2002. http://dx.doi.org/10.2172/833770.

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Hay, Benjamin P., David A. Dixon, and Brian M. Rapko. Computational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), June 2003. http://dx.doi.org/10.2172/833780.

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Hay, Benjamin P., and Brian M. Rapko. Computational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), June 2004. http://dx.doi.org/10.2172/838770.

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Hay, Benjamin P., David A. Dixon, and Brian M. Rapko. Computational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), June 2000. http://dx.doi.org/10.2172/827037.

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Raymond, Kenneth N., Jide Xu, and Christine Gramer. Rational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), June 1999. http://dx.doi.org/10.2172/830032.

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Raymond, Kenneth N. Rational Design of Metal Ion Sequestering Agents. Office of Scientific and Technical Information (OSTI), September 2000. http://dx.doi.org/10.2172/831152.

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Pertzborn, Amanda J. Intelligent Building Agents Laboratory: Hydronic System Design. National Institute of Standards and Technology, September 2016. http://dx.doi.org/10.6028/nist.tn.1933.

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