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1

Rodrigues, Celso A., Maria C. R. Luvizotto, Ana Liz G. Alves, Piero H. M. Teodoro, and Elisa A. Gregório. "Digital dermatitis of the accessory digits of dairy cows." Pesquisa Veterinária Brasileira 30, no. 3 (March 2010): 246–48. http://dx.doi.org/10.1590/s0100-736x2010000300010.

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This report characterizes the digital dermatitis (DD) lesions in the accessory digits of dairy cows and presents data on the applied therapy. Fifteen Holstein cattle with DD affecting the accessory digits of the hindlimbs from four dairy farms with previous history of DD were evaluated. Lesions were excised, the wounds were sutured, and a topical application of oxytetracycline powder covered by bandaging was associated with a single parenteral administration of long acting oxytetracycline IM (20mg/kg). Tissue samples were obtained for histopathology and transmission electronic microscopy (TEM). Lesions from all the animals were recuperated 15 days after surgical procedure. Overal, most DD lesions were papillomatous epidermal projections or wartlike verrucous lesions. Histopathologically, samples revealed hyperplasia of epidermis with hyperkeratosis, several mitoses in the stratum basale and elongated rete ridges in the superficial and middle dermis. TEM revealed long, thin spirochete-like bacteria. Morphologic features of lesions and its response to therapy were comparable to those described for DD.
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2

Blowey, R., M. Sharp, and S. Done. "Digital dermatitis." Veterinary Record 131, no. 2 (July 11, 1992): 39. http://dx.doi.org/10.1136/vr.131.2.39-a.

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3

Vermeersch, A., and G. Opsomer. "Digital dermatitis in cattle." Vlaams Diergeneeskundig Tijdschrift 88, no. 5 (October 31, 2019): 259–68. http://dx.doi.org/10.21825/vdt.v88i5.15997.

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Digital dermatitis is the most common cause of lameness worldwide in dairy cattle. In this final part of a twin paper, treatment options and strategies to prevent digital dermatitis are reviewed. There is a wide range of different treatments available but none of them can completely cure the animal. Footbaths and applying high standards for hygiene are ways to keep this disease under control. Moreover, the link to other (human and non-human) treponemal diseases will be discussed. In humans, treponemes are involved in periodontal disease, syphilis and many other illnesses. The dermatological manifestation of some of these human diseases such as yaws have a similar appearance like acute digital dermatitis. Digital dermatitis-like lesions have been described in goats, sheep and elks. The typically isolated Treponema spp. can also be found in equine proliferative pododermatitis affected feet. Besides in digital dermatitis, these bacteria can be found in bovine ulcerative mammary dermatitis and badly healing lesions in cattle.
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4

Rashmir-Raven, Ann M., Sharon S. Black, Lora G. Rickard, and Mark Akin. "Papillomatous Pastern Dermatitis with Spirochetes and Pelodera Strongyloides in a Tennessee Walking Horse." Journal of Veterinary Diagnostic Investigation 12, no. 3 (May 2000): 287–91. http://dx.doi.org/10.1177/104063870001200320.

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Papillomatous digital dermatitis is a common disease in cattle. The pastern dermatitis observed in a horse shared many of the gross characteristics of papillomatous digital dermatitis in cattle. Lesions included a mixture of proliferative and erosive changes, with a verrucose appearance in some areas. Microscopic similarities included pseudoepitheliomatous and papillomatous epidermal hyperplasia with hyperkeratosis, spongiosis of the epidermis, and intraepidermal spirochetes. The horse was also concurrently infected with Pelodera strongyloides. Papillomatous digital dermatitis in cattle is associated with poor husbandry practices. The environment of the affected horse was heavily contaminated with urine, manure, and other organic debris. Verrucous pododermatitis of horses may be the same as or similar to bovine papillomatous digital dermatitis, and these conditions have similar etiologies.
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5

Vermeersch, A., and G. Opsomer. "Digital dermatitis in cattle." Vlaams Diergeneeskundig Tijdschrift 88, no. 5 (October 31, 2019): 247–58. http://dx.doi.org/10.21825/vdt.v88i5.15996.

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Digital dermatitis or Mortellaro’s disease is a highly prevalent bovine dermatological disorder situated in the foot region that causes lameness and impairs animal welfare. In this first part of a twin paper, the role of genetics, immunity, bacteria and hygiene in the development of this complex disease are described. There is still no consensus regarding the role of the immune system and the typically isolated Treponema spp. in the pathogenesis of digital dermatitis. Moisture and dirt are undoubtedly important for disease transmission in and between dairy farms; furthermore, the genetic component of the disease will be more deeply discussed.
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6

Logue, D. "Understanding bovine digital dermatitis." Veterinary Record 168, no. 8 (February 25, 2011): 212–13. http://dx.doi.org/10.1136/vr.d1284.

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7

Lewis, C. "Contagious ovine digital dermatitis." Veterinary Record 169, no. 24 (December 9, 2011): 642. http://dx.doi.org/10.1136/vr.d7967.

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8

Blowey, Roger. "Clinical Forum: Digital dermatitis." Livestock 11, no. 4 (July 2006): 20–27. http://dx.doi.org/10.1111/j.2044-3870.2006.tb00033.x.

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9

Wilson-Welder, Jennifer H., Jarlath E. Nally, David P. Alt, Mitchell V. Palmer, John Coatney, and Paul Plummer. "Experimental Transmission of Bovine Digital Dermatitis to Sheep: Development of an Infection Model." Veterinary Pathology 55, no. 2 (November 16, 2017): 245–57. http://dx.doi.org/10.1177/0300985817736572.

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Digital dermatitis is an infectious cause of lameness primarily affecting cattle but also described in sheep, goats, and wild elk. Digital dermatitis is a polymicrobial infection, involving several Treponema species and other anaerobic bacteria. Although the exact etiology has not been demonstrated, a number of bacterial, host, and environmental factors are thought to contribute to disease development. To study host–bacterial interactions, a reproducible laboratory model of infection is required. The objective of this study was to demonstrate key aspects of bovine digital dermatitis lesions in an easy-to-handle sheep model. Crossbred sheep were obtained from a flock free of hoof disease. Skin between the heel bulb and dewclaw was abraded before wrapping to emulate a moist, anaerobic environment. After 3 days, abraded areas were inoculated with macerated lesion material from active bovine digital dermatitis and remained wrapped. By 2 weeks postinoculation, experimentally inoculated feet developed erosive, erythematous lesions. At 4 weeks postinoculation, microscopic changes in the dermis and epidermis were consistent with those described for bovine digital dermatitis, including erosion, ulceration, hyperkeratosis, ballooning degeneration of keratinocytes, and the presence of neutrophilic infiltrates. Silver staining of lesion biopsy sections confirmed that spirochetes had penetrated the host epidermis. The model was then perpetuated by passaging lesion material from experimentally infected sheep into naïve sheep. This model of bovine digital dermatitis will allow for future novel insights into pathogenic mechanisms of infection, as well as the development of improved diagnostic methods and therapeutics for all affected ruminants.
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10

Moreira, Tiago Facury, Elias Jorge Facury Filho, Leandro Silva Andrade, Luiz Fernando Cardoso Labre, Karolliny Merlo Goehringer, Otavio Luiz Fidelis Junior, Letícia Marques Rodrigues, Odael Spadeto Jùnior, Guilherme Vieira Fonseca, and Antônio Ultimo Carvalho. "Dermatite digital bovina: etiologia e rotas de transmissão." Revista Acadêmica Ciência Animal 16 (December 14, 2018): 1. http://dx.doi.org/10.7213/1981-4178.2018.163101.

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A dermatite digital (DD) é uma das principais doenças do sistema locomotor de bovinos que levam os animais à claudicação e causam graves prejuízos econômicos. Desde o seu primeiro relato na Itália, em 1974, a DD atingiu uma situação endêmica em diversos países, incluindo o Brasil. Bactérias do gênero Treponema são os principais agentes envolvidos, pois se apresentam como as bactérias mais abundantes e também estão presentes nas partes mais profundas das lesões. Mais de 20 espécies diferentes de Treponema foram identificados em amostras de DD, sendo as espécies T. pedis, T. medium, T. phagedenis, T. refringens e T. denticula as mais relatadas. Uma diversidade de outras bactérias como Mycoplasma, Fusobacterium, Porphyromonas, Bacteroides spp., Campylobacter spp., Guggenheimella spp. e D. nodosus também foram descritas. Tentativas de induzir a doença artificialmente só foram bem sucedidas com o uso de macerado de lesões ativas, demonstrando a importância do sinergismo bacteriano. Apesar da quantidade de estudos sobre o tema, a determinação da etiologia definitiva da DD permanece sendo um desafio, principalmente em relação ao papel que as diferentes bactérias encontradas desempenham no desenvolvimento da lesão. A epidemiologia desta doença também apresenta aspectos pouco esclarecidos, como os possíveis reservatórios e como ocorre a sua transmissão. Os filotipos de Treponema envolvidos na DD foram detectados na cavidade oral, rúmen, fezes e no ambiente de fazendas que possuíam a doença, porém sempre em pequenas quantidades, o que mantém em questão a importância destes locais como reservatórios.
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11

Nagamine, Claude M., Fernando Castro, Ben Buchanan, James Schumacher, and Linden E. Craig. "Proliferative Pododermatitis (Canker) with Intralesional Spirochetes in Three Horses." Journal of Veterinary Diagnostic Investigation 17, no. 3 (May 2005): 269–71. http://dx.doi.org/10.1177/104063870501700311.

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Spirochetes were identified histologically in canker (proliferative pododermatitis) in 3 horses. The data suggest that spirochetes may contribute to the pathology of equine chronic foot diseases similar to the manner in which they contribute to the pathology of bovine papillomatous digital dermatitis and contagious ovine digital dermatitis.
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12

Ishmael, R., T. Goodman, J. Martin, and C. Stockwell. "A comparison of the effectiveness of oxytetracycline or salt water in the management of digital dermatitis in dairy cattle." Proceedings of the British Society of Animal Science 2005 (2005): 207. http://dx.doi.org/10.1017/s1752756200011182.

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Digital dermatitis is one of the main causes of lameness in dairy cattle, possibly accounting for 25% of the reported cases of lameness (Watson, 1999). With lameness being attributed to reduced milk yields and increased calving intervals there are considerable economic implications and effective treatment and prevention regimes are essential. Topical antibiotic treatment is the most common method of treating digital dermatitis in the UK although there is currently only one product licensed for use (Terramycin spray, Pfizer Animal Health) which contains oxytetracycline. Although effective, there can be various problems (e.g. antibiotic resistance) associated with using antibiotics for the management of digital dermatitis meaning that a suitable prevention regime that uses a non-antibiotic solution instead would be desirable. One possible alternative is sodium chloride solution (salt water) which is hypertonic and would therefore cause the bacterial cells to dehydrate, inhibiting cell growth and multiplication. This trial aimed to investigate the effect of topical application of either oxytetracycline or sodium chloride solution on the pre-washed rear feet of cows for the prevention/treatment of digital dermatitis in dairy cattle.
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13

Nicoletti, José Luiz de Mello, Francisco Armando de Azevedo Souza, Armen Thomassian, Carlos Alberto Hussni, and Ana Liz Garcia Alves. "Prevalência de lesões podais e graus de claudicação em vacas leiteiras mantidas em confinamento permanente ("free-stall" e "tie-stall")." Revista de Educação Continuada em Medicina Veterinária e Zootecnia do CRMV-SP 4, no. 2 (July 1, 2001): 24–32. http://dx.doi.org/10.36440/recmvz.v4i2.3315.

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São apresentadas as prevalências de lesões podais e claudicação em vacas da raça Holandesa Preta e Branca, em confinamento permanente tipo "free-stall" e "tie-stall", em fazendas do Estado de São Paulo. Prevaleceram no sistema "free-stall": dermatite digital, sola plana e erosão axial e no sistema "tie-stall": hemorragia da sola, doença da linha branca, erosão dos talões, sola dupla, dermatite interdigital, fissuras no casco e pinça longa/talão baixo. Não houve correlação entre as lesões encontradas em cada animal com a presença de claudicação. O sistema de manejo exerceu influência sobre a taxa de prevalência das lesões podais que, entretanto, pode ser diferente entre fazendas que adotam sistemas semelhantes.
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14

Logue, D. N., J. E. Offer, R. A. Laven, and W. A. Ellis. "Digital dermatitis – The aetiological soup." Veterinary Journal 170, no. 1 (July 2005): 12–13. http://dx.doi.org/10.1016/j.tvjl.2005.04.030.

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15

Sullivan, L. E., S. D. Carter, R. Blowey, J. S. Duncan, D. Grove-White, and N. J. Evans. "Digital dermatitis in beef cattle." Veterinary Record 173, no. 23 (October 7, 2013): 582.1–582. http://dx.doi.org/10.1136/vr.101802.

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16

Blowey, R. "Digital dermatitis in dairy cattle." Veterinary Record 121, no. 13 (September 26, 1987): 311. http://dx.doi.org/10.1136/vr.121.13.311-c.

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17

Blowey, R., and M. Sharp. "Digital dermatitis in dairy cattle." Veterinary Record 122, no. 21 (May 21, 1988): 505–8. http://dx.doi.org/10.1136/vr.122.21.505.

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18

Bell, Nick J. "Digital dermatitis: treatment and control." Livestock 18, no. 2 (March 2013): 6–12. http://dx.doi.org/10.12968/live.2013.18.2.6.

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19

Duncan, Jennifer, Dai Grove‐White, and Joe Angell. "Understanding contagious ovine digital dermatitis." In Practice 40, no. 2 (December 22, 2017): 60–65. http://dx.doi.org/10.1136/inp.j4812.

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20

Marčeková, Paulína, Marián Mad’ar, Eva Styková, Jana Kačírová, Miriam Sondorová, Pavol Mudroň, and Zdeněk Žert. "The Presence of Treponema spp. in Equine Hoof Canker Biopsies and Skin Samples from Bovine Digital Dermatitis Lesions." Microorganisms 9, no. 11 (October 20, 2021): 2190. http://dx.doi.org/10.3390/microorganisms9112190.

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Equine hoof canker and bovine digital dermatitis are infectious inflammatory diseases of the hooves with an unknown etiology. However, anaerobic spirochetes of the genus Treponema are considered to be potential etiological agents. The aim of this study was to find a suitable way to isolate DNA and to detect the presence of treponemal DNA in samples of equine hoof canker and bovine digital dermatitis. DNAzol®® Direct and column kits were used to isolate DNA from samples of equine hoof canker and bovine digital dermatitis. The presence of Treponema spp. was detected using PCR and Sanger sequencing. DNAzol®® Direct is suitable for isolating DNA from these types of samples. Treponemal DNA was detected in equine hoof samples as well as in bovine digital dermatitis skin samples. In equine hoof biopsies, the most frequently detected was Treponema pedis (8/13). Treponema brennaborense (2/13) and Treponema denticola (2/13) were also found. In the case of bovine digital dermatitis, Treponema medium ssp. bovis was confirmed in 14 of 36 skin samples. Treponema pedis (9/36), Treponema vincentii (1/36), Treponema phagedenis (1/36), and Treponema brennaborense (1/36) were detected as well. DNAzol®® Direct was more appropriate for isolation of treponemal DNA because the columns isolation method was more equipment and time-consuming. The presence of several Treponema spp. was determined in the samples. In horses, the most commonly detected species was a T. pedis, while in cattle it was T. medium ssp. bovis.
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21

Alsaaod, M., J. Plüss, E. Studer, and A. Steiner. "Non-antibiotic treatment of interdigital hyperplasia secondary infected with digital dermatitis treponemes in dairy cows." Schweiz Arch Tierheilkd 163, no. 12 (December 5, 2021): 871–75. http://dx.doi.org/10.17236/sat00333.

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22

Nuss, Karl. "Footbaths: The solution to digital dermatitis?" Veterinary Journal 171, no. 1 (January 2006): 11–13. http://dx.doi.org/10.1016/j.tvjl.2005.02.010.

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23

Hesseling, J., A. R. Legione, M. A. Stevenson, C. I. McCowan, M. F. Pyman, C. Finochio, D. Nguyen, et al. "Bovine digital dermatitis in Victoria, Australia." Australian Veterinary Journal 97, no. 10 (July 8, 2019): 404–13. http://dx.doi.org/10.1111/avj.12859.

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24

Hemming, T. "Research on contagious ovine digital dermatitis." Veterinary Record 169, no. 26 (December 22, 2011): 690. http://dx.doi.org/10.1136/vr.d8250.

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25

Laven, Richard. "Control of digital dermatitis in cattle." In Practice 23, no. 6 (June 2001): 336–41. http://dx.doi.org/10.1136/inpract.23.6.336.

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26

McLENNAN, MW, and RA McKENZIE. "Digital dermatitis in a Friesian cow." Australian Veterinary Journal 74, no. 4 (October 1996): 314–15. http://dx.doi.org/10.1111/j.1751-0813.1996.tb13788.x.

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27

O'Connell, Niamh. "Digital dermatitis: tackling an emerging problem." Veterinary Record 173, no. 23 (December 13, 2013): 577–78. http://dx.doi.org/10.1136/vr.f7223.

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28

Cruz, C., D. Driemeier, C. Cerva, and L. G. Corbellini. "Bovine digital dermatitis in southern Brazil." Veterinary Record 148, no. 18 (May 5, 2001): 576–77. http://dx.doi.org/10.1136/vr.148.18.576.

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29

Laven, Richard. "Treatment of contagious ovine digital dermatitis." Veterinary Record 179, no. 16 (October 21, 2016): 416.1–416. http://dx.doi.org/10.1136/vr.i5646.

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30

Angell, Joseph, Dai Grove-White, Helen Williams, and Jennifer Duncan. "Treatment of contagious ovine digital dermatitis." Veterinary Record 179, no. 16 (October 21, 2016): 416.2–416. http://dx.doi.org/10.1136/vr.i5647.

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31

Heinlin, Julia, Birgit Knoppke, Elisabeth Kohl, Michael Landthaler, and Sigrid Karrer. "Dermatitis Herpetiformis Presenting as Digital Petechiae." Pediatric Dermatology 29, no. 2 (August 16, 2011): 209–12. http://dx.doi.org/10.1111/j.1525-1470.2011.01401.x.

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32

Sullivan, L. E., N. J. Evans, R. W. Blowey, D. H. Grove-White, S. R. Clegg, J. S. Duncan, and S. D. Carter. "A molecular epidemiology of treponemes in beef cattle digital dermatitis lesions and comparative analyses with sheep contagious ovine digital dermatitis and dairy cattle digital dermatitis lesions." Veterinary Microbiology 178, no. 1-2 (July 2015): 77–87. http://dx.doi.org/10.1016/j.vetmic.2015.04.011.

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33

Cherkasov, V. G., О. Ye Маievskyi, I. V. Serheta, I. M. Makarchuk, and N. M. Smolko. "Qualitative signs of digital dermatoglyphics as markers of diseases of atopic nature." Biomedical and Biosocial Anthropology, no. 34 (February 28, 2019): 5–12. http://dx.doi.org/10.31393/bba34-2019-01.

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The lawfulness of the application of the method of dermatoglyphics in the study of atopic diseases is ensured by the polygenic inheritance of signs of dermatoglyphics, on the one hand, and the pathogenetic heterogeneity of these diseases, on the other hand, as well as high informative ability of signs of dermatoglyphics as markers of diseases of hereditary and multifactorial nature. The purpose of the study is to detect differences in qualitative signs of digital dermatoglyphics between patients with atopic dermatitis, allergic rhinitis and bronchial asthma. Primary indicators of digital dermatoglyphics of sick young men and young women of the Podillia region are taken from the data bank of the research center of the National Pirogov Memorial Medical University, Vinnytsya and were used in previous studies when compared with the practically healthy population of this region. Imprints were obtained by the method of “printing ink” by Gladkova T. D. By the method of Cummins H. and Midlo Ch. a dermatological study was performed for 320 young men and young women with allergic rhinitis (n=69), bronchial asthma (n=108) and atopic dermatitis (n=143). The frequency and location of 8 types of finger patterns were subject to analysis. Statistical processing of the obtained results was carried out in the package “Statistica 6.1” using nonparametric methods. The reliability of the difference in values between independent qualitative values was determined by the formula of Weber E. (1961). The specificity of the digital typology of atopic diseases is established, which is based on the differences in the frequency and location of the whorl, central pocket and arches between the young men, except those indicated - a random pattern between young women, patients with atopic dermatitis, bronchial asthma, allergic rhinitis. Additionally, when comparing young men, patients with allergic rhinitis with patients with bronchial asthma and atopic dermatitis - ulnar loop; for bronchial asthma with patients with allergic rhinitis and atopic dermatitis - lateral pocket loop (in young men) and ulnar, lateral pocket and double loops (in young women); when comparing young men, patients with atopic dermatitis with patients with bronchial asthma, and allergic rhinitis - a random pattern.
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34

Pozzatti, Pricilla Nascimento, Fernando Passon Casagrande, Marcus Dantas Dórea, Luiz Felipe Nunes Menezes Borges, Lenir Cardoso Porfírio, Hyran Bernardes Pinheiro, and Paulo Cesar Amaral Ribeiro da Silva. "Prevalência das afecções podais em vacas leiteiras da região sul do estado do Espírito Santo, Brasil." Revista Acadêmica Ciência Animal 16 (December 14, 2018): 1. http://dx.doi.org/10.7213/981-4178.2018.163003.

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O presente estudo teve como objetivo principal realizar o levantamento das principais afecções podais que acometem os bovinos na região do sul capixaba do estado do Espírito Santo. Foram avaliadas propriedades leiteiras contemplando diferentes sistemas de produção, classificados nas categorias extensivo, semiconfinamento e confinamento. De 1225 vacas leiteiras examinadas, 25 apresentaram pelo menos um tipo de lesão podal, identificando-se um total de 64 lesões. A prevalência das afecções podais foi de 2,04%. Das afecções de casco, 82,10% ocorreram nos membros posteriores e 17,90% nos membros anteriores. As afecções de maior frequência encontradas no presente estudo foram erosão de talão (18,75%), dermatite interdigital (14,07%), pododermatite séptica e dermatite digital (10,94% cada), e úlcera de sola (9,37%). O conhecimento da prevalência das afecções podais na região sul do Espírito Santo nos permite identificar possíveis falhas de manejo existentes e estabelecer medidas profiláticas de maneira mais eficiente.
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35

Walker, R. L., D. H. Read, K. J. Loretz, and R. W. Nordhausen. "Spirochetes isolated from dairy cattle with papillomatous digital dermatitis and interdigital dermatitis." Veterinary Microbiology 47, no. 3-4 (December 1995): 343–55. http://dx.doi.org/10.1016/0378-1135(95)00114-x.

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36

Corlevic, Alicia T., and David S. Beggs. "Host Factors Impacting the Development and Transmission of Bovine Digital Dermatitis." Ruminants 2, no. 1 (January 14, 2022): 90–100. http://dx.doi.org/10.3390/ruminants2010005.

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This review provides insight on potential host-specific factors that increase individual susceptibility to infection and transmission of bovine digital dermatitis. Digital dermatitis is increasing in prevalence within herds worldwide and yields economic losses for producers and welfare issues for animals. A total of 34 relevant studies were reviewed based on the inclusion criteria. A decrease in susceptibility to disease was found in animals with specific genomic and hoof characteristics, thus citing the importance of sire selection when designing a breeding program. Animals with superior health status that lacked co-morbidities and mounted immune responses to infection were less likely to develop disease. Primiparous cattle and those in peak production were more likely to develop lesions, as were over-or-under-conditioned Holstein–Friesian breeds. Cattle with superior hoof conformation and gait were poor hosts for bacteria and therefore less likely to develop and spread infection. The lowest risk of transmission of digital dermatitis occurred during the dry period and post peak lactation and cattle with advanced lesions contributed to the persistence of the disease within a herd. It is hoped that this review will help producers design breeding and management programs for their herds, and help veterinarians advise clients on the subject.
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37

Staton, Gareth J., Amy Gillespie, Nicholas J. Evans, Roger Blowey, and Stuart D. Carter. "Controlling the spread of bovine digital dermatitis." Journal of Dairy Research 87, no. 1 (February 2020): 140. http://dx.doi.org/10.1017/s0022029920000072.

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38

Davies, I. "Treatment options for contagious ovine digital dermatitis." Veterinary Record 169, no. 23 (December 2, 2011): 604–5. http://dx.doi.org/10.1136/vr.d7759.

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39

Sheldon, I. "Digital and interdigital dermatitis in dairy cattle." Veterinary Record 134, no. 21 (May 21, 1994): 559–60. http://dx.doi.org/10.1136/vr.134.21.559.

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40

Duncan, J. S., J. W. Angell, S. D. Carter, N. J. Evans, L. E. Sullivan, and D. H. Grove-White. "Contagious ovine digital dermatitis: An emerging disease." Veterinary Journal 201, no. 3 (September 2014): 265–68. http://dx.doi.org/10.1016/j.tvjl.2014.06.007.

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41

Knappe-Poindecker, M., M. Gilhuus, T. K. Jensen, K. Klitgaard, R. B. Larssen, and T. Fjeldaas. "Interdigital dermatitis, heel horn erosion, and digital dermatitis in 14 Norwegian dairy herds." Journal of Dairy Science 96, no. 12 (December 2013): 7617–29. http://dx.doi.org/10.3168/jds.2013-6717.

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42

Bell, Nick J. "Latest concepts relevant to treatment of digital dermatitis in dairy cattle." Livestock 27, no. 2 (March 2, 2022): 54–62. http://dx.doi.org/10.12968/live.2022.27.2.54.

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Digital dermatitis is one of the most common lesions causing lameness in dairy cattle, also affecting beef cattle and sheep. It is a highly infectious polymicrobial infection, with several species of treponeme implicated. Many treatments appear efficacious and given the animal appears the main reservoir of infection, there are strong arguments for proactive targeted treatment of cows with lesions leading to improved welfare, production and disease control. This article explores the antibacterial treatment options for digital dermatitis and some adjunctive therapies that can improve cure rates. Licensed topical antibiotics generally achieve a good outcome, but non-antibiotic alternatives may be preferable for ethical reasons and for chronic or mild lesions. There is a strong rationale for providing non-steroidal anti-inflammatory drugs to reduce pain and inflammation associated with infections. Optimal bandaging technique is still poorly understood and despite the evidence, opinion remains deeply divided on their use.
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43

Mudroň, P. "Effects of Manure Bedding on the Rate of Claw Diseases in Dairy Cows." Folia Veterinaria 60, no. 4 (December 1, 2016): 14–19. http://dx.doi.org/10.1515/fv-2016-0032.

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Abstract This study was conducted to determine the prevalence of claw diseases in dairy cows housed on two different bedding systems: deep straw bedding and unsterilized recycled manure solids. On the farm (farm A) with the straw bedding, 403 and on the farm (farm B) with manure solid bedding, 226 dairy cows were examined. The prevalence of cows with one or more claw lesions on the farm with straw bedding and with manure solids were 37 % and 69 %, respectively (P < 0.001). In both bedding systems, two claw lesions dominated: digital dermatitis and inflammatory disorders of corium (white line diseases, toe ulcer, and sole ulcer). The prevalence of the digital dermatitis housed in deep-bedded freestalls and in freestalls with manure solids were 17.8 % and 53.1 % (P < 0.001), respectively. The prevalence of the white line diseases and toe ulcer were 12.1 % and 15.7 % on farm A and 3.88 % and 2.59 % on farm B, respectively (P < 0.001). There was no significant difference in the prevalence of the sole ulcer between farms. These data indicate a relatively high prevalence of claw lesions on the studied dairy farms. Moreover, a long-term contact of claws with manure (boxes and corridors) on the farm with unsterilized recycled manure solids seems to be associated with a higher prevalence of digital dermatitis.
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Gillespie, Amy, and Nicholas Evans. "Infection reservoirs and transmission of digital dermatitis in the dairy herd." Livestock 25, no. 3 (May 2, 2020): 118–24. http://dx.doi.org/10.12968/live.2020.25.3.118.

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This article discusses the aetiology of digital dermatitis (DD), summarises key research in the field, and emphasises more recent advances in terms of our understanding of infection reservoirs and transmission of disease. It also identifies areas for future development enabled by technological advances.
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45

Sauter-Louis, C., J. Maierl, and A. Fiedler. "Polyurethane dressing, tetracycline and salicylic acid use for treatment of digital dermatitis in cattle." Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere 43, no. 06 (2015): 350–58. http://dx.doi.org/10.15653/tpg-140751.

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SummaryObjective: The use of antibiotics is a proven approach for local and systemic treatment of digital dermatitis (DD). Even if they are administered only locally and at low dosage, their use should be restricted to an absolute minimum. The efficacy of a commercial polyurethane wound dressing in treating acute digital dermatitis was compared with topical treatment using a commercially available tetracycline spray and a salicylic acid paste. Materials and methods: A total of 105 cows in a dairy farm (with about 160 dairy cows) were included in the study, with 101 cows needing topical treatment for digital dermatitis on one or both hind feet. All animals underwent hoof trimming prior to the treatment. Affected feet (n = 152) were randomly assigned to one of three comparable treatment groups. Topical treatment was administered to all visible digital dermatitis lesions. Animals in the positive control groups were given a topical treatment of tetracycline (53 DD lesions in 49 cows) or salicylic acid (53 DD lesions in 50 cows) formulations, whose therapeutic effects were scientifically verified. Spray was applied once, at a usual dosage and without any bandage. Salicylic acid paste was fixed in place with a bandage for 5 days. In the test group (46 DD lesions in 45 cows), a polyurethane bandage was left in place for 10 days. Whereas, 47 feet (from 38 cows) without lesions or with lesions showing no pain were designated as group 0. Each lesion was evaluated at day 0 during trimming, and on day 10 and 36. The lesions were scored based on severity and size. Results: All groups showed a statistically significant improvement in the clinical appearance of the lesions at day 10. There were no significant differences in the findings between the second and the third evaluation (day 10 and day 36) either within a group or between the groups. Conclusion: The use of an alternative treatment regimen like a polyurethane wound dressing shows good clinical healing, it is as effective as the conventional methods, and unlike the conventional methods, does not require a latency period.
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Mudroň, P., T. Höskuldsson, and X. Mihajlovičová. "Prevalence of Claw Diseases in Dairy Cows with Different Body Condition." Folia Veterinaria 61, no. 3 (September 1, 2017): 19–22. http://dx.doi.org/10.1515/fv-2017-0023.

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AbstractThe aim of this study was to examine the relationship between body condition and claw diseases in dairy cows. The data used in this study were obtained during two sessions of routine orthopaedic treatment and hoof trimming on a dairy farm in Eastern Slovakia. In the spring and autumn terms, 482 dairy cows were examined for claw diseases and their body conditions were recorded. Out of the 482 dairy cows, 56 % were affected by one or more claw diseases in one or more legs. Digital dermatitis and sole ulcers were the most often detected claw diseases found in this study. The dairy cows with a low body condition score (BCS < 3) showed a higher prevalence of claw diseases (P < 0.05) than the cows with a body condition score greater than 3. However, this difference could not be found when infectious diseases of the claws (digital dermatitis, foot rot, and interdigital dermatitis) were analysed. The results of this study allowed us to conclude that the dairy cows with a lower grade of body condition suffered more from non-infectious claw diseases (sole ulcer, white line diseases).
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MICHELOUD, Juan Francisco, Luis Adrián COLQUE CARO, Gabriel ARGUELLO, Juan ROQUES, and Fernando Martín DELGADO. "Dermatitis digital en novillos de feedlot: Descripción de 2 brotes en el Noroeste Argentino." FAVE Sección Ciencias Veterinarias 17, no. 2 (November 27, 2018): 50–54. http://dx.doi.org/10.14409/favecv.v17i2.7813.

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La Dermatitis Digital (DD) es una afección podal de distribución mundial. Al igual que otras enfermedades que afectan al pie bovino induce a evidentes cojeras, con las consecuentes pérdidas productivas y económicas. Comúnmente se la describe en el ganado lechero y raramente en ganado de carne. En este trabajo se presentan dos brotes de DD en novillos de feed-lot del Noroeste Argentino. Se destacan aspectos clínicos, epidemiológicos, patológicos y de diagnóstico. La incidencia fue de 5 y 35 %. Las lesiones se identificaron típicamente en el área palmar de los miembros posteriores e histopatológicamente se observó una dermatitis necrotizante con infiltrado neutrofílico. Mediante la tinción Warthin-Starry se identificaron espiroquetas intralesionales en el 50% (4/8) de las muestras colectadas.
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Cernek, Preston, Nathan Bollig, Kelly Anklam, and Dörte Döpfer. "Hot topic: Detecting digital dermatitis with computer vision." Journal of Dairy Science 103, no. 10 (October 2020): 9110–15. http://dx.doi.org/10.3168/jds.2019-17478.

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49

Katsoulos, P. D., A. Minas, and G. Christodou. "First Confirmed Case of Digital Dermatitis in Greece." American Journal of Animal and Veterinary Sciences 3, no. 2 (February 1, 2008): 57–61. http://dx.doi.org/10.3844/ajavsp.2008.57.61.

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50

Laven, R. A., and D. N. Logue. "Treatment strategies for digital dermatitis for the UK." Veterinary Journal 171, no. 1 (January 2006): 79–88. http://dx.doi.org/10.1016/j.tvjl.2004.08.009.

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