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Gilchrist, Gail, Sandra Davidson, Aves Middleton, Helen Herrman, Kelsey Hegarty, and Jane Gunn. "Factors associated with smoking and smoking cessation among primary care patients with depression: a naturalistic cohort study." Advances in Dual Diagnosis 8, no. 1 (February 16, 2015): 18–28. http://dx.doi.org/10.1108/add-10-2014-0036.
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Purpose – People with a history of depression are more likely to smoke and less likely to achieve abstinence from smoking long term. The purpose of this paper is to understand the factors associated with smoking and smoking cessation among patients with depression. Design/methodology/approach – This paper reports on smoking prevalence and cessation in a cohort of 789 primary care attendees with depressive symptoms (Centre for Epidemiologic Studies Depression Scale score of=16) recruited from 30 randomly selected Primary Care Practices in Victoria, Australia in 2005. Findings – At baseline, 32 per cent of participants smoked. Smokers were more likely to be male, unmarried, receive government benefits, have difficulty managing on available income, have emphysema, a chronic illness, poor self-rated health, to have more severe depressive and anxiety symptoms, to be taking anti-depressants, to be hazardous drinkers, to report suicidal ideation and to have experienced childhood physical or sexual abuse. At 12 months, 20 participants reported quitting. Females and people with good or better self-rated health were significantly more likely to have quit, while people with a chronic illness or suicidal ideation were less likely to quit. Smoking cessation was not associated with increases in depression or anxiety symptoms. Only six participants remained quit over four years. Practical implications – Rates of smoking were high, and long-term cessation was low among primary care patients with depressive symptoms. Primary care physicians should provide additional monitoring and support to assist smokers with depression quit and remain quit. Originality/value – This is the first naturalistic study of smoking patterns among primary care attendees with depressive symptoms.
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Benavent, D., M. Garrido-Cumbrera, C. Plasencia, L. Christen, H. Marzo-Ortega, J. Correa-Fernández, P. Plazuelo-Ramos, D. Webb, and V. Navarro-Compán. "AB0500 IMPACT OF COVID-19 PANDEMIC IN OVERALL HEALTH AND FUNCTIONING IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS: RESULTS FROM THE REUMAVID STUDY (PHASE 1)." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 1277.2–1278. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2153.
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Background:Evidence on the impact of the COVID-19 pandemic on the overall health and functioning in patients with axial spondyloarthritis (axSpA) is scarce.Objectives:To analyse the impact of the COVID-19 pandemic on the overall health and functioning in patients with axSpA.Methods:Data from axSpA patients participating in the first phase of the REUMAVID study were analysed. REUMAVID is a cross-sectional, observational study collecting data through an online questionnaire of unselected patients with rheumatic and musculoskeletal diseases (RMDs), recruited by patient organizations. The survey was disseminated during the beginning of the COVID-19 pandemic (April-July 2020) in seven European countries (Cyprus, France, Greece, Italy, Portugal, Spain, and the United Kingdom). Patients with axSpA who completed the ASAS health index (ASAS-HI) questionnaire were included in this analysis. Descriptive analyses were used to present socio-demographic and clinical characteristics, as well as daily habits. Overall health and functioning were defined according to the ASAS-HI (0-17), as follows: good health (ASAS-HI ≤5), acceptable health (ASAS-HI 6-11), and poor health (ASAS-HI ≥12). As secondary outcomes, well-being (WHO-5), self-perceived health status, and HADS for anxiety and depression were assessed.Results:Out of 670 axSpA patients, 587 (87.6%) completed ASAS-HI. Of these, 70.4% were female, 72.6% were married or in a relationship, 46.7% had university studies and 37.6% were currently employed. Mean age was 49.9±12.8 years and mean BMI was 26.7±5.5. Regarding extraarticular manifestations, 13.6% had psoriasis, 12.1% inflammatory bowel disease and 18.7% uveitis. Before the COVID-19 pandemic, 50.9% were receiving biological drugs, 46.3% NSAIDs, 26.4% painkillers, 24.7% conventional DMARDs, and 11.9% oral corticosteroids. According to the ASAS-HI, 19.6 % of patients were classified as having poor health, with the most affected aspects being pain (92.0%), movement (86.5%), maintenance of body position (80.6%), energy (79.0%) and sleep (75.3%). Regarding self-perceived health status, 14% reported their health status as “bad” or “very bad”, and 46.8% reported worsening health during the pandemic (Table 1). A distribution of the results of the total ASAS-HI scores can be seen in Figure 1.Table 1.Overall health and well-being, disease activity, and mental health.Primary Outcome (ASAS-HI)Mean ± SD orn (%)ASAS-HI (0-17), n=5878.0 (±3.9)ASAS-HI <5 (good health)159 (27.1) 5-12 (acceptable health)313 (53.3) ≥12 (poor health)115 (19.6)Secondary OutcomesWHO-5 WHO-5, (0-100), n=58446.3 (±23.1) WHO- 5 Poor wellbeing WHO- ≤50330 (56.5)Self-perceived health status, n=585 Very good33 (5.6) Good214 (36.6) Fair256 (43.8) Bad69 (11.8) Very bad13 (2.2)Change in health status during lockdown, n=587 Much worse than before54 (9.2) Moderately worse220 (37.6) Same as before270 (46.0) Moderately better35 (6.0) Much better than before6 (1.0)HADSHADS Anxiety (0-21), n=5878.4 (±4.1)HADS Anxiety No case (0-7)248 (42.7) Borderline case (8-10)151 (26.0) Case (11-21)182 (31.3) HADS Depression (0-21), n=5877.0 (±4.3)HADS Depression No case (0-7)329 (56.6) Borderline case (8-10)134 (23.1) Case (11-21)118 (20.3)Figure 1.Distribution of the result of ASAS-HI scores (N= 587)Conclusion:One out of five patients with axSpA reported poor health and functioning according to the ASAS-HI, and almost half of patients reported worsening self-perceived health status during the first wave of the COVID-19 pandemic.Keywords: COVID-19, axial spondyloarthritis, ASAS-HI, healthDisclosure of Interests:Diego Benavent Grant/research support from: Abbvie, Novartis and Roche, Marco Garrido-Cumbrera: None declared., Chamaida Plasencia Grant/research support from: Pfizer, Sanofi, Novartis, Roche and Lilly, Laura Christen Employee of: Novartis Pharma AG, Helena Marzo-Ortega Grant/research support from: Abbvie, Celgene, Janssen, Elli-Lilly, Novartis, Pfizer, UCB and Takeda Pharmaceutical Company, José Correa-Fernández: None declared., Pedro Plazuelo-Ramos: None declared., Dale Webb: None declared., Victoria Navarro-Compán Grant/research support from: Abbvie, BMS, Lilly, MSD, Novartis, Pfizer, Roche, UCB.
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Powles, William E., and Mary G. Alexander. "Was Queen Victoria Depressed? 1. Natural History and Differential Diagnosis of Presenting Problem." Canadian Journal of Psychiatry 32, no. 1 (February 1987): 14–19. http://dx.doi.org/10.1177/070674378703200105.
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For some years we have speculated as to whether Queen Victoria suffered a definable psychiatric illness in her notorious and prolonged seclusion after the Prince Consort's death. We here summarize criteria for grief and depression from three authorities. Against these, we examine the natural history of the Queen's bereavement and restitution. We find that her suffering and her portrayal of the role of widow were related to her personal style and were culturally accepted. Her self-esteem, ego functions, and object relatedness were preserved. While some clinicians might favour a diagnosis of Dysthymic Disorder, we find the evidence strongly in favour of an intense, prolonged, normal human grief (Uncomplicated Bereavement of DSM III) coloured by a romantic and histrionic personal style. Intensity and duration do not, in this case, establish a diagnosis of depression.
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Garrido-Cumbrera, M., H. Marzo-Ortega, J. Correa-Fernández, S. Sanz-Gómez, L. Christen, and V. Navarro-Compán. "POS1175 ASSESSMENT OF THE COVID-19 PANDEMIC FROM THE PERSPECTIVE OF PEOPLE WITH RHEUMATIC MUSCULOSKELETAL DISEASES IN EUROPE. RESULTS FROM THE REUMAVID STUDY (PHASE 1)." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 868–69. http://dx.doi.org/10.1136/annrheumdis-2021-eular.956.
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Background:The COVID-19 pandemic is an unprecedented public health crisis affecting people worldwide, including those with rheumatic and musculoskeletal diseases (RMDs).Objectives:REUMAVID aims to assess the impact of the COVID-19 pandemic and lockdown on the wellbeing, mental health, disease activity and function, access to health care and treatment, support services, and hopes and fears of people RMDs.Methods:REUMAVID is an international collaboration led by the Health & Territory Research group at University of Seville, Spain, together with a multidisciplinary team including patient organization and rheumatologists. This cross-sectional study consisting of an online survey gathering data from patients with a diagnosis of 15 RMDs in Cyprus, France, Greece, Italy, Portugal, Spain and the United Kingdom. Participants are recruited by patient organizations. Data is collected in two phases: 1) during the first peak of the COVID-19 pandemic (Spring 2020), and 2) as a follow-up to the pandemic (Winter 2020). This analysis presents descriptive results of the aggregated data, summarizing continuous and categorical variables.Results:A total of 1,800 RMD patients have participated in the first wave of the COVID-19 pandemic (from early April to mid-June 2020). The most frequent reported diagnosis were axial spondyloarthritis (37.2%), rheumatoid arthritis (29.2%) and osteoarthritis (17.2%). Mean age was 52.6±13.2, 80.1% were female, 69.6% were in a relationship or married and 48.6% had university studies. In total, 1.1% had tested positive for COVID-19, 10.8 % reported symptoms but were not tested, while 88.1% did not experience any symptoms. 46.6% reported worsening health during the pandemic. 63.9% perceived their health status to be “fair to very bad”. Access to care was limited with 58.4% being unable to keep the rheumatologist appointment, of which, 35.2% were cancelled by the provider and 54.4% was attended by phone or online. 15.8% changed their medication, for which 65.5% were changed by the provider and 24.6% by own decision. Reported wellbeing and psychological health during the pandemic was poor, with 49.0% reporting poor wellbeing according to the WHO-5 scale, 57.3% marking as anxiety and 45.8% as depression in the HADS scale. During the pandemic, 24.6% smoked and 18.2% drank more than before and 54.5% were unable to exercise at home.Conclusion:Results from the first phase of REUMAVID show disturbance of the healthcare quality, substantial changes in harmful health behaviors and an unprecedented impairment of mental health in REUMAVID participants. REUMAVID will continue to collect information in order to assess the impact of the COVID-19 pandemic in people affected by RMDs across Europe.Acknowledgements:This study was supported by Novartis Pharma AG. We would like to thank all patients that completed the survey as well as all of the patient organisations that participated in the REUMAVID study including: the Cyprus League Against Rheumatism (CYPLAR) from Cyprus, the Association Française de Lutte Anti-Rhumatismale (AFLAR) from France, the Hellenic League Against Rheumatism (ELEANA) from Greece, the Associazione Nazionale Persone con Malattie Reumatologiche e Rare (APMARR) from Italy, the Portuguese League Against Rheumatic Diseases (LPCDR), from Portugal, the Spanish Federation of Spondyloarthritis Associations, the Spanish Patients’ Forum (FEP), UNiMiD, Spanish Rheumatology League (LIRE), Andalusian Rheumatology League (LIRA), Catalonia Rheumatology League and Galician Rheumatology League from Spain, and the National Axial Spondyloarthritis Society (NASS), National Rheumatoid Arthritis (NRAS) and Arthritis Action from the United Kingdom.Disclosure of Interests:Marco Garrido-Cumbrera: None declared, Helena Marzo-Ortega Speakers bureau: AbbVie, Biogen, Celgene, Janssen, Lilly, Novartis, Pfizer, Takeda and UCB, Consultant of: AbbVie, Celgene, Janssen, Lilly, Novartis, Pfizer and UCB, Grant/research support from: Janssen and Novartis, José Correa-Fernández: None declared, Sergio Sanz-Gómez: None declared, Laura Christen Employee of: Novartis Pharma AG, Victoria Navarro-Compán Grant/research support from: Abbvie, BMS, Janssen, Lilly, MSD, Novartis, Pfizer, Roche, and UCB.
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Fehily, Sasha, Grant Blashki, Fiona Judd, Leon Piterman, and Hui Yang. "Case studies in mental health in general practice: depression and malignancy." Family Medicine and Community Health 1, no. 3 (September 1, 2013): 57–60. http://dx.doi.org/10.15212/fmch.2013.0314.
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Christogiorgos, Stelios, Eleni Stavrou, Marie-Ange Widdershoven-Zervaki, and John Tsiantis. "Brief psychodynamic psychotherapy in adolescent depression: Two case studies." Psychoanalytic Psychotherapy 24, no. 3 (September 2010): 262–78. http://dx.doi.org/10.1080/02668734.2010.491212.
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Elgudin, Larissa, Sunil Kishan, and Don Howe. "Depression in Children and Adolescents with Cystic Fibrosis: Case Studies." International Journal of Psychiatry in Medicine 34, no. 4 (December 2004): 391–97. http://dx.doi.org/10.2190/n7dl-l6pe-mkyh-4910.
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Hale, A. S., A. W. Procter, and P. K. Bridges. "Clomipramine, Tryptophan and Lithium in Combination for Resistant Endogenous Depression: Seven Case Studies." British Journal of Psychiatry 151, no. 2 (August 1987): 213–17. http://dx.doi.org/10.1192/bjp.151.2.213.
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Seven patients suffering from severe endogenous depression who had proven resistant to lengthy trials of treatment with tricyclic and other antidepressants are described. Their successful treatment with a combination of clomipramine, L-tryptophan and lithium is discussed in the context of other strategies for the treatment of resistant depression.
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Copeland, John. "Depression of older age." British Journal of Psychiatry 174, no. 4 (April 1999): 304–6. http://dx.doi.org/10.1192/bjp.174.4.304.
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BackgroundThe EURODEP collaboration was formed to take advantage of existing studies of random community samples of older people in Europe, using GMS–AGECAT for case identification and diagnosis. Later, other centres joined, and the EURO–D scale was developed to harmonise the different methods used with the GMS. Previous studies had revealed different levels of depression in Europe but had been confounded by the use of unreconcilable methods. These studies attempt to overcome this problem.AimsTo introduce the first set of publications from the EURODEP collaboration.Method results and conclusionsPresented in five accompanying papers (pp. 307–345, this issue)
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Mesquita, Maria Eugênia, Maria Eliza Finazzi, Bruno Gonçalves, Lee Fu-I, Leandro L. Duarte, José Ricardo Lopes, José Alberto Del-Porto, and Luiz Menna-Barreto. "Activity/rest rhythm of depressed adolescents undergoing therapy: case studies." Trends in Psychiatry and Psychotherapy 38, no. 4 (December 2016): 216–20. http://dx.doi.org/10.1590/2237-6089-2015-0053.
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Abstract Introduction: Disorders of circadian rhythms have been reported in studies of both depressed children and of depressed adolescents. The aim of this study was to evaluate whether there is a relationship between the 24-hour spectral power (24h SP) of the activity/rest rhythm and the clinical course of depression in adolescents. Methods: Six 14 to 17-year-old adolescents were recruited for the study. They were all suffering from major depressive disorder, according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria, as identified by the Schedule for Affective Disorders and Schizophrenia for School Aged Children: Present and Lifetime Version (K-SADS-PL). Depressive symptoms were assessed using the Children's Depression Rating Scale - Revised (CDRS-R) and clinical evaluations. Locomotor activity was monitored over a period of 13 consecutive weeks. Activity was measured for 10-minute periods using wrist-worn activity monitors. All patients were prescribed sertraline from after the first week up until the end of the study. Results: We found a relationship between high CDRS values and low 24-hour spectral power. Conclusions: The 24h SP of the activity/rest rhythm correlated significantly (negatively) with the clinical ratings of depression.
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Wood, Debra A., Debra A. Wood, and Philip M. Burgess. "Epidemiological Analysis of Electroconvulsive Therapy in Victoria, Australia." Australian & New Zealand Journal of Psychiatry 37, no. 3 (June 2003): 307–11. http://dx.doi.org/10.1046/j.1440-1614.2003.01182.x.
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Objective: To determine the population-based utilization rate of electroconvulsive therapy (ECT) in Victoria between 1998–1999, to examine the characteristics of the ECT treated group, and to identify patient factors independently associated with differential rates of ECT treatment. Method: Electroconvulsive therapy is reported under statute in Victoria, Australia. Crude, age-adjusted and age–sex specific utilization rates were calculated using this statutory data for the 1998–1999 financial year and estimated mid-year populations from the Australian Bureau of Statistics. Descriptive characteristics of those treated with ECT were derived from the statutory data. Patient factors associated with an increased likelihood of ECT in the public sector were explored with logistic regression analysis, using non-ECT treated mental health patients from the Victorian Psychiatric Case Register as the reference population. Results: The crude treated-person and age-adjusted rates for the State (both public and private sectors) were 39.9 and 44.0 persons per 100 000 resident population per annum, respectively. The crude and age-adjusted administration rates were 330.3 and 362.6 ECT administrations per 100 000 resident population per annum, respectively. Age–sex specific rates varied by age and sex, with rates generally increasing with age and female sex. Overall, 62.8% of the treated group were women, 32.9% aged over 64, and 75.2% had depression. Diagnosis, age and sex each independently predicted ECT in the public sector, with diagnosis the most important factor, followed by age then sex. Conclusions: Despite decades of use, the appropriate rate of ECT utilization is still unclear. Further research should be directed at exploring the factors, including provider variables, determining ECT treatment.
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Tye, Christine S., and Paul E. Mullen. "Mental Disorders in Female Prisoners." Australian & New Zealand Journal of Psychiatry 40, no. 3 (March 2006): 266–71. http://dx.doi.org/10.1080/j.1440-1614.2006.01784.x.
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Objective: The objective of the study was to investigate the rates of mental disorder among women in prison in Victoria, and to compare with community rates. Design: A midnight census of all women in prison in Victoria was undertaken. Respondents were interviewed with a version of the Composite International Diagnostic Interview (CIDI), an adapted version of the Personality Diagnostic Questionnaire (PDQ-4+) and a demographics questionnaire. Main Outcome Measures: Twelve-month prevalence rates of ICD-10 mental disorders including depressive disorders, anxiety disorders and drug-related disorders were examined. Prevalence of personality disorders was also investigated. Results: Eighty-four per cent of the female prisoners interviewed met the criteria for a mental disorder (including substance harmful use/dependence) in the year prior to interview. This rate was reduced to 66% when drug-related disorders were excluded. Fortythree per cent of subjects were identified as cases on a personality disorder screener. For all disorders, (except obsessive-compulsive disorder and alcohol harmful use) women in prison had a significantly greater likelihood of having met the 12-month diagnostic criteria when compared to women in the community. The most prevalent disorders among the female prisoners were: drug use disorder (57%), major depression (44%), Posttraumatic stress disorder (36%), and personality disorders. Almost a quarter (24%) of respondents were identified as a ‘case’ on the psychosis screen. Conclusions: In the present study female prisoners had significantly higher rates of the mental disorders investigated (with the exceptions of OCD and alcohol harmful use) when compared with women in the community. The pattern of disorder found among female prisoners is consistent with the abuse literature, suggesting that histories of abuse among the prison population may account for part of the discrepancy. These results highlight the need for improved assessment and treatment resources to meet the demands of this population.
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Shaik, Subahani, and Ravi Philip Rajkumar. "Post-vasectomy depression: a case report and literature review." Mental Illness 6, no. 2 (September 2, 2014): 40–42. http://dx.doi.org/10.1108/mi.2014.5494.
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Vasectomy is a commonly performed and relatively safe procedure, with low reported rates of psychological morbidity, though there is some variability across studies. Depression following a vasectomy is relatively infrequent. A married man aged 30 developed a chronic depressive episode, lasting four years and resistant to an adequate trial of fluoxetine, following a vasectomy. His depression was heralded by a post-operative panic attack, and was accompanied by medically unexplained symptoms and the attribution of all his symptoms to the procedure – a belief that was shared by his family. Psychological complications of vasectomy have generally been studied under four heads: sexual dysfunction, effects on marital relationships, chronic post-operative pain, and other complications including anxiety and depression. These complications have generally been reported at higher rates in developing countries, and are linked to poor knowledge about the procedure and inadequate pre-operative counseling. The implications of the existing literature for the patient's current complaints, and the mechanisms and risk factors involved, are discussed in the light of existing research. Suggestions for the prevention and treatment of post-vasectomy depression are also outlined.
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Smith, Daniel J., and Douglas H. R. Blackwood. "Depression in young adults." Advances in Psychiatric Treatment 10, no. 1 (January 2004): 4–12. http://dx.doi.org/10.1192/apt.10.1.4.
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Depression, as a heterogeneous collection of disorders, is likely to include subgroups that are more genetic in origin. In common with other neuropsychiatric disorders such as schizophrenia, Alzheimer's disease and Huntington's disease, earlier age at onset in depression is associated with higher genetic loading and poorer long-term outcome. Adolescents and young adults with depression are also at high risk of developing a bipolar illness. This article reviews depressive illnesses that occur for the first time in adolescence and young adulthood. Case studies are used to discuss atypical presentations and the evolving concept of bipolar-spectrum disorders.
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Sadaf, Tahira, Muhammad Amjed Iqbal, Fariha Jamil, Muhammad Haseeb Raza, and Adnan Nazir. "Cost of Mental Illness and Depression in Developing Countries: A Case Study of Pakistan." Journal of Education and Social Studies 3, no. 2 (August 30, 2022): 84–94. http://dx.doi.org/10.52223/jess.20223204.
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Depression causes a substantial burden to persons, their beloved ones, and the nations as a whole. Major depression results in disability, high morbidity, high mortality, suicides, physical and mental impairment, and deteriorates the quality of life in a society. Depression is common in developing countries like Pakistan. This study analyzes the economic burden of depression and depressive disorders in Pakistan. The study was conducted in Pakistan’s third largest city, Faisalabad. Respondents were selected using a multistage sampling technique. As a first step, hospitals were selected from both the public and private sectors. In step two, respondents were selected and interviewed using a well-structured and pre-tested questionnaire. Review of literature reveals that the largest share of the burden of depression and depressive disorders is in the form of indirect cost. Direct healthcare cost is mostly in the form of outpatient care, doctor fee, and medicine bills, etc. This study, therefore, estimated both types of costs using cost of illness (COI) analysis. In order to find out the level of depression in patients, the center of epidemiologic studies depression (CES-D) scale was used. Then the direct and indirect cost of depression was estimated. Additionally, multiple regression analysis was used to examine the determinants of health cost, including the level of depression. The direct and indirect costs of depression were 11,108 Pakistani Rupees (PKR) and 4,869 PKR per month, respectively. Results of regression analysis revealed that besides the level of depression, monthly income, age, education, and the number of visits to a doctor’s clinic determine health cost, positively and statistically significant. Additionally, the occurrence of depression and anxiety was evident in adults more than other age groups. Females were suffering from this disorder comparatively more than male respondents. The economic burden related to depression is considerable, especially for those who belong to low-income group. Government should provide facilities for treatment for depression in public hospitals by keeping a special focus on less privileged groups of the population.
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Sergey SAVIN. "State Strategies of Russia and China in Mental Health Protection: Case Studies on Juvenile Depression." Far Eastern Affairs 49, no. 002 (June 30, 2021): 72–84. http://dx.doi.org/10.21557/fea.69047850.
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Gavidia-Payne, Susana, Lyn Littlefield, Mats Hallgren, Peter Jenkins, and Neil Coventry. "Outcome Evaluation of a Statewide Child Inpatient Mental Health Unit." Australian & New Zealand Journal of Psychiatry 37, no. 2 (April 2003): 204–11. http://dx.doi.org/10.1046/j.1440-1614.2003.01124.x.
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Objective: To assess the impact of inpatient intervention, provided by a child mental health unit in Victoria, Australia, on a number of key child and family variables. Method: Pre-post test design with a four-month follow up was applied to assess changes across time. Twenty-nine parents, 42 teachers, and 37 referrers provided reports on a series of child, parent, and family functioning measures. Results: Significant improvements in child behaviour and functioning, parenting competency and efficacy, parenting practices, and reduced parental depression were observed over time. Changes in family functioning scores were not significant; however, univariate analysis indicated improvements in two individual subscales. Conclusions: There is a lack of studies of the outcome of inpatient interventions of children in psychiatric settings. However, as shown in the present study, improvements in functioning can be detected and obtained with short-term interventions that focus on both children and families. Methodological shortcomings (i.e. absence of comparison groups) and lack of specificity in intervention variables, however, are difficulties yet to be overcome in evaluation research of inpatient treatment.
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Savarkar, Tushar, and Shankar Das. "Mental Health Problems among Street Children: The Case of India." Current Research Journal of Social Sciences and Humanities 2, no. 1 (June 25, 2019): 39–46. http://dx.doi.org/10.12944/crjssh.2.1.05.
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A number of studies indicate that street children are vulnerable for exposure to poly-victimization, which includes various types of physical abuse, sexual violence, bullying and exposure to violence, neglect, drug abuse. These children may suffer severe mental health outcomes due to chronic exposure to psychosocial distress, specifically anxiety and depression. An analytical review of the literature was undertaken to examine the research studies on the psychological and social impact of the living condition on the street children from both a national and global lens. Research evidence indicates that there is a strong correlation between mental health and overall holistic development of the individual. The paper finally provides a conceptual framework of vulnerabilities and mental health of street children, implications for future research, interventions and public policy.
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Gelabert, E., S. Subirà, L. Garcia-Esteve, P. Navarro, A. Plaza, E. Cuyàs, and R. Martín-Santos. "Perfectionism and other risk factors in postpartum depression: a case-control study." European Psychiatry 26, S2 (March 2011): 1095. http://dx.doi.org/10.1016/s0924-9338(11)72800-0.
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IntroductionAlthough perfectionism has generally been associated with depressive illness in general, there are no studies on its role in major depression in the postnatal period. The aim of the present study was to explore the relationship between perfectionism and major postpartum depression.MethodsIn this case-control study, we compared the differences in perfectionism dimensions between 122 women with major postpartum depression (SCID-I; DSM-IV) and 115 healthy postpartum women. The Frost Multidimensional Perfectionism Scale (FMPS) was used to assess perfectionism. Other variables were also considered: Socio-demographic and obstetric data, psychiatric history, other personality traits, social support, life events and genotype combinations according to serotonin transporter expression (5-HTTLPR and Stin2 VNTR polymorphisms).ResultsMultivariate models confirmed perfectionism as an independent factor associated with major postpartum depression. The FMPS dimension concern over mistakes was associated with a 4-fold increase in risk for major postpartum depression (OR = 4.14; 95%CI: 1.24–13.81). Neuroticism, personal psychiatric history and 5-HTT low-expressing genotypes at one of the loci were also identified as independent factors.ConclusionsPerfectionism, and particularly the concern over mistakes perfectionism dimension, is associated with major postpartum depression. These results highlight the importance of assessing personality traits together with other risk factors to identify women at risk of depression after childbirth.
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Heerde, Jessica A., Gabriel J. Merrin, Vi T. Le, John W. Toumbourou, and Jennifer A. Bailey. "Health of Young Adults Experiencing Social Marginalization and Vulnerability: A Cross-National Longitudinal Study." International Journal of Environmental Research and Public Health 20, no. 3 (January 17, 2023): 1711. http://dx.doi.org/10.3390/ijerph20031711.
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People who experience social marginalization and vulnerability have uniquely complex health needs and are at risk of poor health outcomes. Regression analyses using longitudinal data from a cross-national, population-based sample of young adults participating in the International Youth Development Study, tested associations between social marginalization and vulnerabilities and physical health, mental health, and substance use outcomes. Participants from Victoria, Australia, and Washington State in the US were surveyed at ages 25 (2014) and 29 years (2018; N = 1944; 46.7% male). A history of adverse childhood experiences (ACEs), LGBT identity, financial insecurity, and justice system involvement at age 25 predicted poor health outcomes at age 28, including lower perceived health status, risk for chronic illness, depression and anxiety symptoms, and diagnosed mental health/substance use disorders. Tests of model equivalence across states showed that a history of ACEs was more strongly related to health status and serious injury at age 28 and justice system involvement at age 25 was more strongly related to age 28 serious injury in Victoria than in Washington State. Findings strengthen the case for future population-based research identifying life-course interventions and state policies for reducing poor health and improving health equity among members of socially marginalized groups.
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Poutanen, Outi, Anna-Maija Koivisto, and Raimo K. R. Salokangas. "The Depression Scale (DEPS) as a case finder for depression in various subgroups of primary care patients." European Psychiatry 23, no. 8 (December 2008): 580–86. http://dx.doi.org/10.1016/j.eurpsy.2008.06.007.
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AbstractPurposeThe quick and simple Depression Scale (DEPS) has been a popular self-rating depression scale in Finland for nearly 15 years. The purpose was to assess the validity of the DEPS in various subgroups of patients.Materials and methodsPrimary care patients, aged 18–64, completed a postal questionnaire including the DEPS. Of the 1643 patients all screen-positive subjects and every 10th screen-negative subject were invited for interview (the Present State Examination, PSE). Complete DEPS scores were available for 410 patients. They were grouped by gender, age, marital status, perceived physical health, basic education and the Michigan Alcoholism Screening Test (MAST) score. Separately for each subgroup, receiver operating characteristic (ROC) curve analyses were done, sensitivity, specificity, area under the curve (AUC), predictive values and likelihood ratios were calculated, and Cronbach's α was estimated.ResultsThe DEPS was valid in general, but best for patients with basic education longer than 9 years.DiscussionThe key statistical figures for the DEPS were comparable to the figures for other short self-rating scales.ConclusionThe DEPS is a valid case finder for primary care patients in the age group 18–64 years, and especially suitable for more highly educated patients. Future studies comparing the DEPS with other simple depression rating scales are needed.
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Javid Ahmad, Dar, and Amber Shagufa. "Effect of Pulmonary Rehabilitation on the Health-Related Quality of Life (Hqol), Activities of Daily Living (ADL) and mental health among COVID-19 patients; A systematic review." Archives of Depression and Anxiety 8, no. 1 (March 17, 2022): 005–12. http://dx.doi.org/10.17352/2455-5460.000068.
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Objective: It is a systematic review on the COVID-19 and its post complication by using pulmonary rehabilitation as an intervention. This review paper aims at collecting, focusing, and presenting the current evidence and information on pulmonary rehabilitation to patients with COVID-19 and also its effect upon the HRQoL, ADL and mental health. Design: It is a systematic review, where 3756 studies were searched on the web of science, Scopus, PubMed, PEDro, and google scholar. published from 18th Jan 2020-19th Sep 2020. We searched the reference lists of selected studies, registries, international clinical trials, and respiratory conference abstracts to look for qualifying studies. Selection criteria; Randomised controlled trial, case reports, cohort and cross-sectional studies in which pulmonary rehabilitation as an intervention in COVID-19 patients and its effect on the HRQoL, ADL and mental anxiety depression health were included. Result: Eleven, out of 3765 studies were included, consisting of 4 RCTs, 4, cross-sectional, 2 case reports, and one cohort the studies evaluated effects of PR on HQoL, ADL, mental health, anxiety, and depression. In COVID-19 patients. The 11 studies included evaluated HQoL, ADL and mental health. among these Four studies reported using SF-36, IE (impact of the event) scale, and VAS. Three studies evaluated ADL through the FIM scale and Barthel index. Five studies evaluated mental health, depression, and anxiety using SDS (Self-Rating Depression Scale), SAS (Self-Rating Anxiety Scale), STAI (State-Trait Anxiety Scale), PHQ-9 (physical health questionnaire), MHLS(Mental Health Lifestyle Scale) and HADS(hospital anxiety and depression scale). Conclusion: The studies included in this systematic review showed that PR is an effective treatment option for patients with COVID-19, its post complications, and the effects upon HQoL, ADL, mental health, depression, and anxiety. There is a future need for more studies of a high methodological quality addressing PR effects on COVID-19 patients. Trial registration number: PROSPERO CRD42020209619.
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Qiu, Xing, Senmao Zhang, Xin Sun, Haiou Li, and Donghua Wang. "Unintended pregnancy and postpartum depression: A meta-analysis of cohort and case-control studies." Journal of Psychosomatic Research 138 (November 2020): 110259. http://dx.doi.org/10.1016/j.jpsychores.2020.110259.
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Castillo, A., M. Lloret, M. Harto, A. Tatay, C. Almonacid, and R. Calabuig. "Electroconvulsive Therapy and Depression with Psychotic Symptoms: a Case Report." European Psychiatry 26, S2 (March 2011): 1136. http://dx.doi.org/10.1016/s0924-9338(11)72841-3.
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IntroductionPsychotic symptoms in depression are indicators of severity and poor prognosis. It usually requires psychopharmacotherapy with antidepressants and antipsychotic agents and it may even require electroconvulsive therapy (ECT).Aims, methodologyTo review the indications of ECT in major depression through the study of a clinical case of a patient admitted in an indoor psychiatric unit.ResultsA 64-year-old woman diagnosed as bipolar affective disorder 20 years ago. Her first manic episode required hospitalization. Afterwards, she remained clinically stable for 18 years with pharmacotherapy with lithium. Lately she was admitted due to a major depressive episode with psychotic features (injury delusions, ruin and catastrophe). Antidepressant and antipsychotic treatment was added, improving her symptoms. However, she had to be readmitted two months later with severe psychotic symptoms that did not improve with pharmacological treatment. ECT was added to her treatment. She improved after a few sessions. During the last years, she has presented depressive episodes with psychotic symptoms at least once a year, and all of them have required ECT.ConclusionsECT is an alternative to pharmacological therapy in depression with psychotic symptoms in patients with no response to drugs. According to studies and clinical practice, ETC has been effective as we see in this case. Therefore, ECT is a technique to consider in major depression, not only in patients who do not respond to drug therapy but also in those who do not tolerate psychopharmacological, who suffer from severe or psychotic symptoms, suicide thoughts or those, psychomotor agitation or stupor.
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Cheifetz, Philip N., George Stavrakakis, and Eva P. Lester. "Studies of the Affective State in Bereaved Children*." Canadian Journal of Psychiatry 34, no. 7 (October 1989): 688–92. http://dx.doi.org/10.1177/070674378903400711.
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The process of bereavement in children ranges from the absence of grief to symptoms of anxiety and conduct disturbances. Some psychoanalytic opinion holds that the absence of grief, associated with lack of cognitive maturity, leads to the development of psychopathology later in life. Other writers describe a mourning response, taking the form of ambivalence, anxiety, and care giving, which may protect against subsequent depression. This paper describes the affective response in 16 children ages four to 17 years, two to three years following the death of a parent, in order to further characterize developmental aspects of the emotional repertoire of bereavement. Only children aged 12 and over were depressed according to the Poznansky Children's Depression Rating Scale and criteria in the DSM-III. Conduct disturbances were observed in the younger children and some of the older children and were correlated with depression in the group as a whole. This suggests that the expression of depressive affect depends on maturation and that the young child may register grief only through anxiety and negativism. Examples of this spectrum of responses are offered in two case vignettes.
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Eales, M. J. "Depression and anxiety in unemployed men." Psychological Medicine 18, no. 4 (November 1988): 935–45. http://dx.doi.org/10.1017/s0033291700009867.
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SynopsisPsychiatric status and psychosocial variables were assessed in a group of 80 unemployed men. Symptoms of depression and anxiety were assessed using the Present State Examination and ‘caseness’ rated according to the Bedford College criteria. Among men who were normal at the time of job loss, 14% developed a ‘case’ disorder and a further 17% a ‘borderline case’ disorder over the first 6 months of unemployment. These rates are similar to those found in studies concerned with a wider range of severe life events. An increased risk of onset was associated with three factors: lack of an intimate relationship with a wife or girlfriend, trait shyness, and preexisting economic difficulties.
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Harvey, Samuel B., Matthew Hotopf, Simon Øverland, and Arnstein Mykletun. "Physical activity and common mental disorders." British Journal of Psychiatry 197, no. 5 (November 2010): 357–64. http://dx.doi.org/10.1192/bjp.bp.109.075176.
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BackgroundPrevious studies have suggested that physical activity may have antidepressant and/or anti-anxiety effects.AimsTo examine the bidirectional relationship between physical activity and common mental disorders and establish the importance of context, type and intensity of activity undertaken.MethodA clinical examination of 40 401 residents of Norway was undertaken. Participants answered questions relating to the frequency and intensity of both leisure-time and workplace activity. Depression and anxiety were measured using the Hospital Anxiety and Depression Scale (HADS). Biological and social data were also collected.ResultsThere was an inverse relationship between the amount of leisure-time physical activity and case-level symptoms of depression. This cross-sectional association was only present with leisure-time (as opposed to workplace) activity and was not dependent on the intensity of activities undertaken. Higher levels of social support and social engagement were important in explaining the relationship between leisure activity and depression. Biological changes such as alterations to parasympathetic vagal tone (resting pulse) and changes to metabolic markers had a less important role.ConclusionsIndividuals who engage in regular leisure-time activity of any intensity are less likely to have symptoms of depression. The context and social benefits of exercise are important in explaining this relationship.
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Anglin, Rebecca E. S., Zainab Samaan, Stephen D. Walter, and Sarah D. McDonald. "Vitamin D deficiency and depression in adults: systematic review and meta-analysis." British Journal of Psychiatry 202, no. 2 (February 2013): 100–107. http://dx.doi.org/10.1192/bjp.bp.111.106666.
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BackgroundThere is conflicting evidence about the relationship between vitamin D deficiency and depression, and a systematic assessment of the literature has not been available.AimsTo determine the relationship, if any, between vitamin D deficiency and depression.MethodA systematic review and meta-analysis of observational studies and randomised controlled trials was conducted.ResultsOne case-control study, ten cross-sectional studies and three cohort studies with a total of 31 424 participants were analysed. Lower vitamin D levels were found in people with depression compared with controls (SMD = 0.60,95% Cl 0.23–0.97) and there was an increased odds ratio of depression for the lowest v. highest vitamin D categories in the cross-sectional studies (OR = 1.31, 95% CI 1.0–1.71). The cohort studies showed a significantly increased hazard ratio of depression for the lowest v. highest vitamin D categories (HR=2.21, 95% CI 1.40–3.49).ConclusionsOur analyses are consistent with the hypothesis that low vitamin D concentration is associated with depression, and highlight the need for randomised controlled trials of vitamin D for the prevention and treatment of depression to determine whether this association is causal.
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Lagha, M., G. Hamdi, N. Dhaouadi, S. Chebli, and R. Ridha. "Depression in women recovered from COVID-19." European Psychiatry 65, S1 (June 2022): S490. http://dx.doi.org/10.1192/j.eurpsy.2022.1245.
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Introduction Studies assessing the psychological impact of COVID-19 have shown that patients with COVID-19 had significantly higher levels of depression, anxiety, and post-traumatic stress symptoms than healthy controls. Objectives The objectives of our study were to assess depression in women recovered from COVID-19 and to compare it to healthy controls. Methods It was a cross-sectional case-control study. We randomly recruited women, from April 1st to 30th, 2021.The women in the case group have been infected with Sars-Cov 2, with a benign or pauci-symptomatic clinical form, and cured for one to two months at the time of the study without any post-COVID complications. Women included in the control group have not been infected with Sars-Cov 2 .Depression was assessed by the Beck Depression Inventory (BDI). Results In total, we recruited 30 women in the case group and 30 women in the control group.The average age of the case group was 35.8 ±6.8 years versus an average age of 35.3 ± 6.33 years in the control group. The majority of coronavirus infections were symptomatic (83.3% (n=25)). The average depression score for the case group was 10.8 ±9.6 corresponding to moderate depression, while the average depression score for the control group was 6.1 ± 6.1 corresponding to mild depression. The presence of depression was more significant in the case group compared to the controls (p=0.003). Conclusions COVID-19 is significantly associated with depression, even in mild or pauci-symptomatic clinical forms. Disclosure No significant relationships.
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Sui, Tiange. "Case Study: Self- Help Manuals Based on Cognitive Therapy for Adult with Depression in China." International Journal of Education and Humanities 6, no. 1 (November 23, 2022): 27–30. http://dx.doi.org/10.54097/ijeh.v6i1.2942.
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The case study follows a 27 years old lady who suffers from depression, which provides an insight into the society and future studies that self-help can also enhance one’s mental health. The patient was in a mild depression and performed violent behaviors and alcohol obsession. Due to the lack of mental health counseling in china’s unique cultural environment, the research provides a self-analysis and self-healing method. Researchers play the role of instructors and observers who would not disturb the participant. The final depression score after six months returns to a normal range. The result also shows in life clues such as less antisocial behaviors and increased self-control. Thus, the case study provides a new idea for mental health education in developing countries or regions. Social workers can provide self-help for people with depression when counseling is not yet widely available in some areas or when people are very resistant to counseling services.
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Dehning, Julia, Heinz Grunze, and Armand Hausmann. "Bupropion Maintenance Treatment in Refractory Bipolar Depression: A Case Report." Clinical Practice & Epidemiology in Mental Health 13, no. 1 (May 31, 2017): 43–48. http://dx.doi.org/10.2174/1745017901713010043.
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Background:The optimal duration of antidepressant treatment in bipolar depression appears to be controversial due to a lack of quality evidence, and guideline recommendations are either vague or contradictive. This is especially true for second line treatments such as bupropion that had not been subject to rigourous long term studies in Bipolar Disorder.Case presentation:We report the case of a 75 year old woman who presented with treatment refractory bipolar depression. Because of insufficient response to previous mood stabilizer treatment and refractory depressive symptoms, bupropion was added to venlafaxine and lamotrigine. From there onwards, the patient improved continuously without experiencing deterioration of depression or a switch into hypomania. Our patient being on antidepressants for allmost four years experienced an obvious benefit from longterm antidepressant administration.Conclusion:Noradrenergic/dopaminergic mechanisms of action may play a more prominent role in bipolar depression, and may still be underused as a therapeutic strategy in the acute phase as well as in long-term maintenance in at least a subgroup of bipolar patients. There is still a lack of evidence from RCTs, but this case report further supports antidepressant long-term continuation and the usefulness of a noradrenergic/dopaminergic antidepressant in the acute and maintenance treatment of bipolar disorder.
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Morrow, Christopher B., and Nithin Krishna. "Depression and suicidality in an Afghan refugee: A case report." Transcultural Psychiatry 56, no. 5 (May 14, 2019): 845–52. http://dx.doi.org/10.1177/1363461519847314.
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We report the case of a young male refugee from Afghanistan who presented after a violent suicide attempt, likely precipitated in part by discrimination and social isolation experienced after immigrating to the United States. Common psychiatric comorbidities associated with immigration from war-torn nations are reviewed with a particular emphasis on how adequate screening and additional resources for vulnerable refugees during and after immigration continues to be an unmet need. Our findings suggest that there is a critical need and additional studies should be conducted, not only to identify at risk refugee populations but also to prevent potentially violent behavior. Our findings also suggest a lack of an optimal screening tool and shed light on the struggles of refugees, particularly those from Afghanistan.
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Randall, Elizabeth J., and Bruce A. Thyer. "Combining Guided Dialog With Cognitive Therapy for Depressed Women: Six Single-Case Studies." Journal of Cognitive Psychotherapy 12, no. 4 (January 1998): 331–42. http://dx.doi.org/10.1891/0889-8391.12.4.331.
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Cognitive therapy (CT) alone was compared to CT, plus a communication skills and relationship repair intervention called Guided Dialog (GD), in the treatment of six depressed women. Outcomes measures were the Beck Depression Inventory and the Miller Social Intimacy Scale, repeatedly administered over time in the context of single-subject research designs. Three women received CT alone, and three received CT followed by CT plus GD. Results indicated that all patients recovered from depression; however, patients who received the combined form of treatment registered greater improvements in intimacy than did clients who received cognitive therapy alone. While tentative, these results suggest that the combination of a relationally based form of treatment such as Guided Dialog, together with cognitive therapy, may warrant a more formal randomized trial.
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Loi, Samantha M., Briony Dow, Kirsten Moore, Keith Hill, Melissa Russell, Elizabeth Cyarto, Sue Malta, David Ames, and Nicola T. Lautenschlager. "Attitudes to aging in older carers – do they have a role in their well-being?" International Psychogeriatrics 27, no. 11 (June 15, 2015): 1893–901. http://dx.doi.org/10.1017/s1041610215000873.
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ABSTRACTBackground:Attitudes to aging have been investigated in non-carer populations and found to have important relationships with physical and mental health. However, these have not been explored in an older carer sample, although it is becoming increasingly important to clarify variables which are linked with positive carer outcomes. This is one of the first studies to report on older carers, their attitudes to aging, and the relationship with carer-related factors.Methods:A cross-sectional study of 202 carers with a mean age of 70.8 years was conducted in Victoria, Australia, using carer demographic data, carer factors such as depression (using the Geriatric Depression Scale), burden (using the Zarit Burden Inventory, ZBI), physical health, personality, and attitudes to aging (using the Attitudes to Aging Questionnaire, AAQ). Spearman rank correlation and hierarchical regression analyses were used.Results:This study showed that carers had overall positive attitudes to aging inspite of their caring role. It also identified that carer factors including depression and burden contributed a significant amount of the variance to attitudes to aging in terms of physical change and psychosocial loss. Personality traits, specifically neuroticism, and extraversion, were also important contributors to attitudes to aging.Conclusions:Results from this study demonstrated that inspite of moderate levels of depression and spending significant time caring, carers reported positive attitudes to aging. Treating depression, decreasing burden, and investigating the benefits of caring may assist older carers maintain their well-being.
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San, Luis, and Belen Arranz. "Mirtazapine: only for depression?" Acta Neuropsychiatrica 18, no. 3-4 (June 2006): 130–43. http://dx.doi.org/10.1111/j.1601-5215.2006.00143.x.
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Background:Mirtazapine is an antidepressant first approved in the Netherlands in 1994 for the treatment of major depressive disorder. However, evidence suggests its effectiveness in a variety of other psychiatric disorders and non-psychiatric medical conditions.Objective:The present paper reviews the published literature on the off-label indications of Mirtazapine.Methods:A search of the relevant literature from MEDLINE, PsycLIT and EMBASE databases, included in the Science Citation Index and available up to March 2006, was conducted using the terms mirtazapine, case-reports, open-label trials and randomized controlled trials. Only articles referring to conditions other than major depression were included in this present review.Results:Off-label use of mirtazapine has been reported in panic disorder, post-traumatic stress disorder, generalized anxiety disorder, social phobia, obsessive-compulsive disorder, dysthymia, menopausal depression, poststroke depression, depression as a result of infection with human immunodeficiency virus, elderly depression, Methylenedioxymethamphetamine (MDMA)-induced depression, hot flashes, alcohol and other substance use disorders, sleep disorders, sexual disorders, tension-type headaches, cancer pain, fibromyalgia, schizophrenia and other less frequent conditions.Conclusions:So far, data on the off-label usefulness of mirtazapine are limited and mainly based on observations from case reports or open-label studies. However, positive cues suggest that confirmation of these preliminary data with randomized controlled trials may give sufficient evidence to warrant the use of mirtazapine in a broad range of disorders.
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Judd, Fiona K., and Anne M. Mijch. "Depression in Patients with HIV and AIDS." Australian & New Zealand Journal of Psychiatry 28, no. 4 (December 1994): 642–50. http://dx.doi.org/10.1080/00048679409080788.
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In this paper we review studies of depression in patients with HIV/AIDS. Methodological issues of importance in understanding and evaluating depression in this patient population are described, and methodological variations between studies, particularly in reference to methods of case detection, diagnostic criteria used and characteristics of the populations studied, are identified. The findings reported in the current literature in general are contrary to what would be expected from an examination of the significant biological and psychosocial stresses of individuals with HIV, and are inconsistent with those of other life-threatening illnesses and CNS diseases. Clear conclusions regarding the prevalence of depression and its effect in patients with HIV/AIDS cannot yet be made.
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Crespo-Delgado, Elena, Verónica Martínez-Borba, and Jorge Osma. "The Unified Protocol for Transdiagnostic Treatment of Perinatal Depression: A Case Study." Clinical Case Studies 19, no. 6 (August 29, 2020): 491–508. http://dx.doi.org/10.1177/1534650120951266.
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This case study aims to present the application of the Unified Protocol (UP) for the Transdiagnostic Treatment of Emotional Disorders in the case of a 38-year-old pregnant woman with a peripartum onset of major depressive disorder and anxiety symptoms. The UP is a cognitive-behavioral intervention based on the shared etiological and maintenance mechanisms of emotional disorders (i.e., mood, anxiety, and related disorders). The UP helps to modify maladaptive emotion-regulation strategies and enhance tolerance of unpleasant and intense emotions (sadness, anxiety, anger, etc.). Whereas previous studies demonstrate the efficacy of the UP in different emotional disorders, to our knowledge, none of them have used the UP to treat perinatal emotional disorders. After the eight UP modules of individual treatment, a significant decrease in anxiety, depression, negative affect, and anxiety sensitivity, and also an increase in positive affect were observed. These results were maintained at the 12-month follow-up. In addition to its clinical utility and acceptance, these results indicate that the UP can be adapted and personalized for the treatment of perinatal emotional disorders. Future studies with larger samples and controlled experimental designs should be developed to demonstrate its efficacy. Furthermore, as the UP seems to be useful in a group format, future efforts should be focused on the UP with perinatal women in a group format.
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Ashton, Melanie M., Olivia M. Dean, Wolfgang Marx, Mohammadreza Mohebbi, Michael Berk, Gin S. Malhi, Chee H. Ng, et al. "Diet quality, dietary inflammatory index and body mass index as predictors of response to adjunctive N-acetylcysteine and mitochondrial agents in adults with bipolar disorder: A sub-study of a randomised placebo-controlled trial." Australian & New Zealand Journal of Psychiatry 54, no. 2 (October 29, 2019): 159–72. http://dx.doi.org/10.1177/0004867419882497.
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Aims: We aimed to explore the relationships between diet quality, dietary inflammatory potential or body mass index and outcomes of a clinical trial of nutraceutical treatment for bipolar depression. Methods: This is a sub-study of a randomised controlled trial of participants with bipolar depression who provided dietary intake data ( n = 133). Participants received 16 weeks adjunctive treatment of either placebo or N-acetylcysteine-alone or a combination of mitochondrial-enhancing nutraceuticals including N-acetylcysteine (combination treatment). Participants were followed up 4 weeks post-treatment discontinuation (Week 20). Diet was assessed by the Cancer Council Victoria Dietary Questionnaire for Epidemiological Studies, Version 2, converted into an Australian Recommended Food Score to measure diet quality, and energy-adjusted dietary inflammatory index score to measure inflammatory potential of diet. Body mass index was also measured. Generalised estimating equation models were used to assess whether diet quality, energy-adjusted dietary inflammatory index score and/or body mass index were predictors of response to significant outcomes of the primary trial: depression symptoms, clinician-rated improvement and functioning measures. Results: In participants taking combination treatment compared to placebo, change in depression scores was not predicted by Australian Recommended Food Score, dietary inflammatory index or body mass index scores. However, participants with better diet quality (Australian Recommended Food Score) reported reduced general depression and bipolar depression symptoms ( p = 0.01 and p = 0.03, respectively) and greater clinician-rated improvement ( p = 0.02) irrespective of treatment and time. Participants who had a more anti-inflammatory dietary inflammatory index had less impairment in functioning ( p = 0.01). Combination treatment may attenuate the adverse effects of pro-inflammatory diet ( p = 0.03) on functioning. Participants with lower body mass index who received combination treatment ( p = 0.02) or N-acetylcysteine ( p = 0.02) showed greater clinician-rated improvement. Conclusion: These data support a possible association between diet (quality and inflammatory potential), body mass index and response to treatment for bipolar depression in the context of a nutraceutical trial. The results should be interpreted cautiously because of limitations, including numerous null findings, modest sample size and being secondary analyses.
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Goutama, Ivany Lestari, Hendsun Hendsun, and Eva Lestari. "A palpable depression." International Journal of Advances in Medicine 9, no. 11 (October 26, 2022): 1120. http://dx.doi.org/10.18203/2349-3933.ijam20222664.
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Several studies have shown that patients with depression, anxiety and stress have a higher ratio in developing atrial fibrillation (AF), with higher proportion occurring in patients with recurrent episodes of AF which are related to severity of disease and increased mortality ratio. We aim to discuss the case of AF caused by mental disorder to examine its relationship and impact in patient’s clinical outcomes. A 70 years-old-man came to clinic with palpitation five days before admission. He often cries and has not been able to sleep since his wife died three months prior. He admits to have neither hope nor desire to do his usual activities or even start new activities. Vital signs show BP 140/90 mmHg, pulse 150x/m, RR 20x/m, SpO2 98%. Cardiopulmonary examination revealed irregular S1-S2. ECG shows premature atrial contraction which evolved to asinus rhythm with HR 150x/minute, AF and incomplete right bundle branch block a months after the first ECG was examined. Depression-Anxiety-stress scoring-42 (DASS-42) was conducted in this patient. Results shows the patient has very severe depression, intermediate anxiety and severe stress. Mental disorders lead to increased etiology of cardiac remodeling factors due to degeneration and sympathetic stimulation, which then induced the AF. Further research is needed to examine whether psychiatric treatment can prevent AF in improving quality of life, healthy behavior and awareness for managing mental health.
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Silva, A., P. Politi, N. Brondino, and M. Olivola. "Efficacy of IV immunoglobulins on depressive symptoms and self-injury: A case report." European Psychiatry 64, S1 (April 2021): S673. http://dx.doi.org/10.1192/j.eurpsy.2021.2021.
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IntroductionSome studies in literature highlight the correlation between immune-mediated inflammatory processes and psychiatric pathologies. However, there are few studies about the efficacy of IV immunoglobulins in psychiatric features (1). (1) ZUNSZAIN, Patricia A.; HEPGUL, Nilay; PARIANTE, Carmine M. Inflammation and depression. In: Behavioral neurobiology of depression and its treatment. Springer, Berlin, Heidelberg, 2012. p. 135-151.ObjectivesCase report: a 39 year patient diagnosed with borderline personality disorder and myasthenia was hospitalized for self-injury ideation, acting out and depressive episode treated with acid valproic, aripiprazole, gabapentin; flare-up of myasthenia that needed treatment.MethodsClinical and test evaluation was performed in three stages: before (t0), immediately after (t1) and 3 weeks after (t2) the administration of the IgEV without other treatment modifications. We have used: - Inventory of Statements About Self-Injury (ISAS) - Barrat Impulsiveness Scale, Version 11 (BIS-11) - Hamilton Anxiety Rating Scale (HAM-A) - Montgomery-Asberg Depression Rating Scale (MADRS) - Alexian Brothers Urge to Selfe-Injure Scale (ABUSI)ResultsThe patient has a score of 79 at BIS-11. She used to have a huge number of acting aout as we see on ISAS (Fig.1).Figure 1Figure 2ConclusionsWe observed a reduction in non-suicidal self-injurious ideation, the suspension of acting-out, a complete remission of depressive symptoms with mild persistence of anxious symptoms immediately after the administration of immunoglobulins, and the remission continue until one month after the administration (Fig.2).DisclosureNo significant relationships.
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Parker, Gordon, Gordon Parker, and Gin Malhi. "Are Atypical Antipsychotic Drugs also Atypical Antidepressants?" Australian & New Zealand Journal of Psychiatry 35, no. 5 (October 2001): 631–38. http://dx.doi.org/10.1080/0004867010060512.
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Objective: To report a case series and review the psychopharmacology of the neuroleptic drugs to suggest that the atypical antipsychotic drugs may have an antidepressant action, at least for those patients with the melancholic subtype. Method: We note the literature suggesting that the older (or typical) antipsychotic drugs were established as having antidepressant activity, describe an open study of some two dozen patients with a treatment-resistant melancholic depression, describe rapid resolution of depression and augmentation benefits associated with commencing an atypical antipsychotic drug in a percentage of subjects, and then review relevant psychopharmacological studies to consider whether there is a rationale for use of antipsychotic drugs to treat depression. Results: Of some two dozen patients treated with an atypical antipsychotic drug, almost immediate improvement was noted in four patients, and evidence of augmentation benefit obtained in another three patients. Conclusions: Impressions from this case series are encouraging. However, as open clinical observational studies are problematic, controlled studies are required to establish whether the atypical antipsychotic drugs have a role in the management of certain expressions of depression, and, in particular, treatment-resistant melancholic depression.
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MOXON, SALLIE, KENNETH LYNE, IAN SINCLAIR, PHILIP YOUNG, and CHRISTINE KIRK. "Mental health in residential homes: a role for care staff." Ageing and Society 21, no. 1 (January 2001): 71–93. http://dx.doi.org/10.1017/s0144686x01008054.
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Two linked studies assess the feasibility of involving care staff in reducing the prevalence of depression in homes for older people. Mental health training was provided for care staff, delivered by members of a Community Mental Health Team for the Elderly. The research programme used quantitative and qualitative methods to evaluate the effects of a theoretical training for care staff, a system of mentoring care staff to reinforce the training; and a care-planning intervention for the management of depression which combined psychosocial and medical approaches. The training programme was positively evaluated by the recipients, the trainers and the researcher who observed it. The ability of care staff to detect depression improved significantly over time, and depression was reduced to below case-level in seven of the eight depressed residents who participated in the care-planning intervention. This research suggests that psychosocial interventions that involve collaboration between carers and residents, supported by a Community Mental Health Team, may have an important part to play in supplementing medical management of depression in residential care homes.
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Ghafoori, Bita. "Prolonged Exposure Therapy for Experiential Avoidance: A Case-Series Study." Clinical Case Studies 17, no. 3 (April 3, 2018): 123–35. http://dx.doi.org/10.1177/1534650118766660.
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Past research has found that experiential avoidance (EA) is a type of avoidance that is common in individuals who report distress associated with traumatic events. No treatment studies to date have evaluated potential changes in EA associated with prolonged exposure therapy (PE), an empirically supported treatment for traumatic distress. This case series presents outcomes associated with treatment by PE for five adults who presented with posttraumatic stress disorder (PTSD), comorbid generalized anxiety disorder (GAD), and problematic EA. PTSD, GAD, depression, and EA symptoms were monitored at baseline, post-treatment, and 1-month follow-up. The five participants reported decreases in PTSD to below clinical cutoff criteria at post-treatment, all five participants reported decreases in depression at post-treatment, and four of the participants showed decreases in GAD and EA at post-treatment. In comparing pre-treatment to 1-month follow-up scores, all the participants reported decreases in PTSD, GAD, depression, and all but one participant reported a decrease in EA. The findings of this study suggest that PE may be a helpful treatment for individuals reporting EA.
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Ihbour, Said, Hammou Anarghou, Abdelmounaim Boulhana, Mohamed Najimi, and Fatiha Chigr. "Mental health among students with neurodevelopment disorders: case of dyslexic children and adolescents." Dementia & Neuropsychologia 15, no. 4 (December 2021): 533–40. http://dx.doi.org/10.1590/1980-57642021dn15-040014.
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ABSTRACT Several research studies have been devoted to study the links between emotional disorders and learning disabilities. However, very minimal of this research has focused on dyslexic students. Objective: The objectives of this study were as follows: (1) to assess self-esteem, anxiety, and depression in dyslexic Arabic-speaking children and adolescents and (2) to describe psychiatric comorbidities in these subjects by comparing them to their non-dyslexic peers. Methods: In total, 205 students (56 dyslexics and 149 good readers), pursuing their education in ordinary schools in the Beni Mellal-Khenifra region of Morocco responded to Taylor’s Self-Assessment Scale of Anxiety, Beck’s Depression Questionnaire, and the Coopersmith Self-Esteem Inventory (SEI). Results: Overall, dyslexics were more anxious, more depressed, and had disturbed self-esteem compared to their non-dyslexic peers. The percentage of psychiatric comorbidity was higher in the dyslexic group. Conclusions: The results of this study highlight the need for a multidisciplinary approach that integrates emotional needs assessment into the rehabilitation care of dyslexic children and adolescents.
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Timulak, Ladislav. "Case studies in emotion-focused treatment of depression: A comparison of good and poor outcome." Counselling and Psychotherapy Research 11, no. 1 (March 2011): 78–80. http://dx.doi.org/10.1080/14733145.2011.548152.
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Huete Naval, M., L. Reyes Molón, C. Regueiro Martín-Albo, R. Galerón, E. Herrero Pellón, and P. Albarracin. "Impulsive traits and dual pathology in patients with depression and alcohol dependence, a case report." European Psychiatry 65, S1 (June 2022): S464. http://dx.doi.org/10.1192/j.eurpsy.2022.1179.
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Introduction Alcohol dependence is one of the most frequent comorbidities in depression. Multiple environmental and neurobiological factors are directly involved in these diseases. In particular, impulsivity is present in many patients with dual pathology and may play a relevant role in its causes, clinical manifestations and prognosis. Objectives To review the relationship between impulsive traits and dual pathology in patients with depression and alcohol dependence. Methods Presentation of a clinical case supported by a non- systematic review of literature containing the key-words “impulsivity”, “depression” and “alcohol dependence”. Results This is a case report of a 43-year-old male with a known history of alcohol dependence and recurrent depression. Interestingly, the patient has a family history of bipolar disorder and alcohol abuse disorder on the paternal side, and frontotemporal dementia on the maternal side. He currently presents a depressive episode associates associated with a significant increase in alcohol consumption. The patient has presented prominent impulsive traits since adolescence that have been aggravated in recent years. This lack of impulse control is described as one of the most relevant factors in relapses in alcohol consumption. Multiple studies correlate the lack of impulse control with a worse prognosis in both alcohol dependence (greater probability of relapses and resistance to treatment) and depression (increased suicide risk). Likewise, an increase in cognitive impulsivity has been observed during depressive episodes, characterized by an inability to inhibit behaviors that have already begun and poor planning capacity, which could lead to a worsening of alcohol abuse. Conclusions Impulsivity traits are related to a worse prognosis in dual pathology due to alcohol and depression, and may present common etiopathogenic mechanisms. Disclosure No significant relationships.
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Löve, Jesper, Monica Bertilsson, Johan Martinsson, Lena Wängnerud, and Gunnel Hensing. "Political Ideology and Stigmatizing Attitudes Toward Depression: The Swedish Case." International Journal of Health Policy and Management 8, no. 6 (March 19, 2018): 365–74. http://dx.doi.org/10.15171/ijhpm.2019.15.
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Background: Stigmatizing attitudes toward persons with mental disorders is a well-established and global phenomenon often leading to discrimination and social exclusion. Although previous research in the United States showed that conservative ideology has been related to stigmatizing attitudes toward mental disorders, there is reason to believe that this mechanism plays a different role in the context of a universal welfare state with a multi-party system such as Sweden. Furthermore, "mental disorders" may signify severe psychotic disorders, which may evoke more negative attitudes. This suggests the importance of specific studies focusing on the more common phenomenon of depression. This paper investigates the relationship between political ideology and stigmatizing attitudes toward depression in Sweden. Methods: This study is part of the New Ways research program. Data were collected by the Laboratory of Opinion Research (LORE) at the University of Gothenburg in 2014 (N = 3246). Independent variables were political ideology and party affiliation. The dependent variable was the Depression Stigma Scale (DSS). Data were analyzed with linear regression analyses and analyses of variance. Results: More conservative ideology (B = 0.68, standard error [SE] = 0.04, P<.001) and more conservative party affiliation (F(8 2920) = 38.45, P<.001) showed more stigmatizing attitudes toward depression. Item-level analyses revealed a difference where the supporters of the conservative party differed (P<.05) from supporters of the liberal party, with a higher proportion agreeing that "people could snap out of " depression if they wanted to; the populist right-wing party differed from the conservative party with a higher proportion agreeing on items displaying people with depression as "dangerous" and "unpredictable." Even self-stigma was highest among the populist right-wing party with 22.3% agreeing that "if I had depression I wouldn’t tell…." Conclusion: Political ideology was associated with stigmatizing attitudes toward depression in Sweden. The results also confirm the need to distinguish between different forms of conservatism by observing social distance as being a more important driver among voters for the populist right-wing party compared with personal agency and responsibility among voters for the more traditional conservative party.
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Guinness, E. A. "I. Relationship Between the Neuroses and Brief Reactive Psychosis: Descriptive Case Studies in Africa." British Journal of Psychiatry 160, S16 (April 1992): 12–23. http://dx.doi.org/10.1192/s0007125000296761.
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Predominant psychopathology in a selected population group - adolescents and young adults at school - in a developing country, is described. The highly selective referral to services was supplemented by active case finding in the community over three years. There were 54 cases of somaticised anxiety (brain fag); 22 cases of depressive neurosis characterised by hypochondriasis, cognitive complaints, and culturally determined paranoid ideation; 23 cases of ‘hysteria’ in the form of dissociative states, pseudoseizures and fugues; and 39 cases of brief reactive psychosis which differed from the dissociative states more in duration and intensity than in form. There was a temporal relationship between transient psychosis and the school calendar. Anxiety or depression often predated the florid psychotic reaction which served as a form of help-seeking behaviour or defence in intolerable stress.
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Baena, R. A., I. Mesián, L. Mendoza, and Y. Lázaro. "Mood disorder in epilepsy: A case report." European Psychiatry 33, S1 (March 2016): S337. http://dx.doi.org/10.1016/j.eurpsy.2016.01.1177.
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IntroductionA lot of studies have described that up to 50% of patients with epilepsy develop psychiatric disorders: depression, anxiety and psychotic symptoms. We can classify these symptoms according to how they relate in time to seizure occurrence, i.e. pre-ictal/prodromal, ictal, post-ictal or inter-ictal. In this case, we have a 76 years old woman that develops a maniac-episode previously that she has an episode.ObjectivesMake a review about the prevalence, risk factors of psychiatric problem in epilepsy (biological, psychosocial and iatrogenic) and report of clinical case.MethodsReview the bi-directional associations between epilepsy and bipolar disorder (epidemiological links, evidence for shared etiology, and the impact of these disorders) with a integrated clinical approach.ResultsTheoretically, epilepsy and bipolar disorder share an important number of clinical and neurobiological features. Classic neuropsychiatric literature focused on major depression with data on bipolar disorder remains limited. However, actually there are many evidences that mood instability, mixed irritability even mania is not uncommon in patients with epilepsy.ConclusionsIt is important develop more sensitive and specific screening instruments to identify mood disorder in epilepsy's patients. Future research becomes decisive for a better understanding of the similarities between epilepsy and BD, and the treatment of both.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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GENSICHEN, J., M. BEYER, C. MUTH, F. M. GERLACH, M. VON KORFF, and J. ORMEL. "Case management to improve major depression in primary health care: a systematic review." Psychological Medicine 36, no. 1 (August 1, 2005): 7–14. http://dx.doi.org/10.1017/s0033291705005568.
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Background. Deficits in the care of depression lead to poor medication adherence, which increases the risk of an unfavourable outcome for this care. This review evaluates effects on symptoms and medication adherence of case management in primary health care.Method. A systematic literature search was performed. The quality of the studies was rated according to the Cochrane Effective Practice and Organization of Care Group (EPOC) criteria. To conduct a subgroup analysis interventions were classified as either ‘standard’ or ‘complex’ case management.Results. Thirteen studies met the inclusion criteria. In a meta-analysis we calculated a standard mean difference/effect size on symptom severity after 6–12 months of −0·40 (95% CI −0·60 to –0·20). Patients in the intervention groups were more likely to achieve remission after 6–12 months [relative risk (RR) 1·39, 95% CI 1·30–1·48]. The relative risk for clinical response was 1·82 (95% CI 1·68–2·05). Patients in intervention groups had better medication adherence than the control group (RR 1·5, 95% CI 1·28–1·86). We found heterogeneous results when assessing effects of different types of intervention.Conclusions. We conclude that case management improves management of major depression in primary health-care settings.