Dissertations / Theses on the topic 'Dentistery'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Dentistery.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Phaneuf, J. André. "La responsabilité du dentiste en matière de soins non thérapeutiques." Sherbrooke : Université de Sherbrooke, 1998.
Find full textConocimiento, Dirección de Gestión del. "Operative Dentistry." Allen Press, 2004. http://hdl.handle.net/10757/655369.
Full textCoirier, François Amador del Valle Gilles Cadeau Emmanuel. "De l'obligation de moyens à l'obligation de résultat ? réflexion sur l'évolution du rapport de confiance entre le chirurgien-dentiste et son patient /." [S.l.] : [s.n.], 2009. http://castore.univ-nantes.fr/castore/GetOAIRef?idDoc=55236.
Full textMonaco, Carlo <1967>. "Zirconia in dentistry." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/5956/1/TESI_MONACO_COMPLETA.pdf.
Full textMonaco, Carlo <1967>. "Zirconia in dentistry." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/5956/.
Full textBroughton, Alan M. "Treatment failures in dentistry." Title page, contents and introduction only, 1988. http://web4.library.adelaide.edu.au/theses/09DM/09dmb875.pdf.
Full textKhatami, Shiva. "Clinical Reasoning in Dentistry." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/27095.
Full textYan, Zhuoqun. "Smart materials in dentistry." Thesis, University of Newcastle Upon Tyne, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430701.
Full textМоскаленко, І. "Using lasers in dentistry." Thesis, Sumy State University, 2016. http://essuir.sumdu.edu.ua/handle/123456789/48840.
Full textKowalski, Michael. "Radiology in forensic dentistry." Thesis, The University of Sydney, 1988. http://hdl.handle.net/2123/4678.
Full textPrzezdziecka, Krystyna. "Profile of Australian dentistry." Thesis, The University of Sydney, 1995. http://hdl.handle.net/2123/4687.
Full textOTTOBELLI, MARCO. "INNOVATION IN RESTORATIVE DENTISTRY." Doctoral thesis, Università degli Studi di Milano, 2017. http://hdl.handle.net/2434/474658.
Full textBjörkvall, Karin. "Dentistry "in the wild" : A workplace study of dentistry from a Distributed cognition perspective." Thesis, Högskolan i Skövde, Institutionen för kommunikation och information, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-5266.
Full textAbuhammoud, Salahaldeen Mohammad. "Knowledge and practice of implant dentistry among University of Iowa College of Dentistry alumni." Thesis, University of Iowa, 2018. https://ir.uiowa.edu/etd/3235.
Full textGlenny, Anne-Marie. "Evidence-based guidelines in dentistry." Thesis, University of Manchester, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527588.
Full textEpasinghe, Don Jeevanie. "Applications of proanthocyanidin in dentistry." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/197558.
Full textpublished_or_final_version
Dentistry
Doctoral
Doctor of Philosophy
Bousdras, Vasileios. "Mechanical loading in implant dentistry." Thesis, Royal Veterinary College (University of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439452.
Full textConocimiento, Dirección de Gestión del. "Dentistry & Oral Sciences Source." Ebsco, 2004. http://hdl.handle.net/10757/655289.
Full textAbdulla, Kamal Chelvakumaran. "Space maintainers in paediatric dentistry." Thesis, Faculty of Dentistry, 1989. http://hdl.handle.net/2123/4277.
Full textZijlstra-Shaw, Sandra. "Assessment of professionalism in dentistry." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/8449/.
Full textTOSCO, VINCENZO. "Nanotechnological applications in clinical dentistry." Doctoral thesis, Università Politecnica delle Marche, 2021. http://hdl.handle.net/11566/290680.
Full textNowadays, developments in the nanotechnology arena have dramatically revolutionized all fields of dentistry from oral diseases to diagnosis, prevention and treatment. The aim of this PhD thesis was to investigate and evaluate the application of nanotechnologies in clinical practice, with particular attention to Preventive, Aesthetic and Restorative dentistry. Caries prevention and early treatment of lesions are priority challenges for clinicians. Nanomaterial-based design, which includes synthetic hydroxyapatite or its derivatives, is able to mimic some of the mechanical and structural properties of native calcified tissues and can definitely promote the remineralization of the enamel structure and prevent dentin hypersensitivity. Moreover, the employment of nanotechnologies in the enrichment of whitening gels by means of nano-forms of hydroxyapatite are widely used to avoid the discomfort and damages associated with bleaching treatments. One of the principal uses of nanoparticles in restorative dentistry is their application as fillers in nanocomposites, providing high ductility without strength loss, scratch resistance, enhanced optical, mechanical and thermal properties. In addition, dental nanocomposites exhibit increased aesthetic properties, such as high gloss retention and excellent polishability and adaptability. Among these ameliorated characteristics, noteworthy are those showed by the new bulk-fill composites. Indeed, due to their novel monomer content and enhanced curing properties, bulk-fill composites let to rapidly obtain a satisfactory adaptation of the material into the cavity, decreasing the chair-time needed, while also ensuring adequate physical characteristics of the surface. Therefore, the application of nanotechnology supports and facilitates the clinician’s needs, which require rapid, safe and repeatable clinical protocols, to obtain the best result in a single appointment.
Leehacharoenkul, Ron R. Bayne Stephen C. Bader James D. McGraw Kathleen A. "Continental distribution of published dentistry citations." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,309.
Full textTitle from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Master of Arts in the Department of Operative Dentistry." Discipline: Operative Dentistry; Department/School: Dentistry.
Gerasym, L. M. "Using general anesthesia in surgical dentistry." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19119.
Full textConocimiento, Dirección de Gestión del. "Guía de acceso para Operative Dentistry." Allen Press, 2021. http://hdl.handle.net/10757/655369.
Full textRosén, Sara. "Tool unit designed for equine dentistry." Thesis, Tekniska Högskolan, Högskolan i Jönköping, JTH, Industridesign, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-45232.
Full textSanches, Diogo Guilherme Dias. "Estudo das principais doenças dentárias em 30 cavalos geriátricos, na região do Alentejos." Master's thesis, Universidade de Évora, 2018. http://hdl.handle.net/10174/23982.
Full textKent, Danae Leda. "Dentist gender and the practice of dentistry /." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09SDN/09sdnk371.pdf.
Full textFugill, Martin. "Simulation and student transition in restorative dentistry." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5724/.
Full textLea, Simon Christian. "The assessment of ultrasonic instruments in dentistry." Thesis, University of Birmingham, 2004. http://etheses.bham.ac.uk//id/eprint/215/.
Full textAl, Saud Lulwah Bint Mohammed Bin Saad A. "Haptic-enhanced learning in preclinical operative dentistry." Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/17111/.
Full textVincent, Aviva. "Feasibility of Canine Support in Pediatric Dentistry." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1554476390381119.
Full textJohnson, Christian Marie. "Quality and Performance Measures in Pediatric Dentistry." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1371821581.
Full textHjalmarsson, Lars. "On cobalt-chrome frameworks in implant dentistry /." Göteborg : Department of Dentistry/Dental Materials Science, Institute of Odontology, 2009. http://hdl.handle.net/2077/21179.
Full textTeixeira, Hugo C. "Wellbeing and Occupational Stress in Dentistry Academics." Thesis, Griffith University, 2022. http://hdl.handle.net/10072/419085.
Full textThesis (Masters)
Master of Philosophy (MPhil)
School of Applied Psychology
Griffith Health
Full Text
SOLIMEI, LUCA. "ADDITIVE MANUFACTURING AND 3D PRINTING IN DENTISTRY." Doctoral thesis, Università degli studi di Genova, 2022. http://hdl.handle.net/11567/1081142.
Full textCerny, Z. J. Comino. "Margaret Estelle Barnes And Annie Praed-Australia'S First Women Graduates In Dentistry: Twentieth Century Femininity And Professionalism In Dentistry." Thesis, The University of Sydney, 2000. http://hdl.handle.net/2123/5098.
Full textKengne, Talla Pascaline. "Déterminants psychosociaux et environnementaux de l'implantation des meilleures pratiques par les dentistes du Québec : cas du renoncement au tabac auprès des adultes fumeurs." Doctoral thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/33288.
Full textTraditionnaly, the predominant approach to healthcare services for dentists was strongly curative and less focused on preventive and promotion of health. Many conditions and diseases are caused by multiple factors. Thus, patient-centred, systemic, and common risk factor approaches are a promising avenue to address these health conditions and improve the quality of care. Dentists are encouraged to engage in general health promotion practices, including the oral health and in the knowledge translation activities. In this manner, targeted interventions are optimal strategies to overcome real and perceived barriers to change by dentists and to favour evidence-based dental practice. Grounded in these principles, this research is related to the science and practice of knowledge translation. Using an exploratory, sequential, mixed methods approach with theory-based underpinnings, this study aims to explore individual and environmental determinants influencing the implementation of Canadian smoking cessation guidelines (5As: Ask, Advise, Assess, Assist and Arrange) by dentists in private practice in Quebec. The first article used a qualitative design and an integrative conceptual framework composed of three theoretical perspectives, including Mintzberg’s Organizational Configuration Theory, Friedson’s Theory of Professions, and Meyer, Rowan, Dimaggio and Powell’ s Institutional Theory to understand organizational, contextual, economic, educational and political factors influencing the adoption of the 5As in private dental clinics in Quebec. Individual semi-directed interviews of 35 to 45 minutes were conducted with 20 private practice dentists. The audio-recorded data were transcribed verbatim, followed by a directed content analysis. Findings indicated that the patient is at the heart of smoking cessation counselling in dental practice in Quebec. Dentists’ attitude and behaviour are affected by different factors including dentist’s leadership style; and the availability of community, human and material resources. Also, other variables include the culture of dental medicine, the compatibility of Canadian smoking cessation guidelines with the practice of dentistry, time constraints, and the lack of reimbursement of counseling practices. The second article was a study carried out to develop and test the psychometric properties of a questionnaire based on a modified version of Triandis’ theory of Interpersonal Behavior (TIB) for exploring the psychosocial determinants of Quebec dentists’ intention to use the Canadian clinical practice guidelines on smoking cessation. Using a mixed-methods exploratory sequential design, a quantitative questionnaire was developed from the results of a qualitative study. Twenty-seven dentists who had not been involved in other aspects of the research project participated in this test-retest. Confirmatory factor analysis was carried out to assess if items supported the predefined basis of TIB-constructs. The final version of the questionnaire has 40 items measuring psychosocial constructs. Confirmatory factor analysis corroborates the theory. Reliability analyses indicate good results with standardized Cronbach alpha ranging from 0.74 to 0.94 and temporal stability coefficients from 0.69 to 0.94. The final article is a cross-sectional study that was carried out on a sample of 59 dentists who had not been involved in other aspects of the research project who were working in private practice between January and September 2016. The study was conducted using a validated and anonymous questionnaire based on a modified version of the Triandis’ Theory of Interpersonal Behaviour. The purpose of this study was to identify the underlying individual mechanisms supporting dentists’ intention to adopt the Canadian smoking cessation clinical guidelines in Quebec. Dentists had a positive intention to use the Canadian guidelines on smoking cessation. Four statements of smoking cessation guidelines like ask-advice-assist and arrange/referwere current in dental practice at the variables proportions. The main predictors of dentists’ intention were professional norm (β=0.85; p≤ 0.0001) and control beliefs (β=0.30; p=0.01), explaining 63 % of variance in dentists’ intention to adopt these guidelines in their practices. Mixed data analysis has shown the major fundamental factors included in the construction of dentists’ professional identity. The results strongly suggest the role of universities and professional dental associations in order to encourage dentists to take a more active role to counsel adult smokers and to have an evidence-based practice.
Chintapalli, Ravi Kiran. "Influence of sandblasting on zirconia in restorative dentistry." Doctoral thesis, Universitat Politècnica de Catalunya, 2012. http://hdl.handle.net/10803/96981.
Full textThe use of tetragonal zirconia polycrystals (3Y-TZP) in dental restorations such as crowns and implants has recently increased attention due to their very good aesthetic appearance and mechanical properties in addition to biocompatibility. The restorations undergo several surface treatments such as sandblasting for better adhesion to luting cements and veneering porcelain. However, there is some controversy about using sandblasted crowns, as sandblasting introduces surface flaws and defects that can compromise the strength of the crown as well as crystallographic changes at the surface. Though the effect of sandblasting in zirconia has been previously studied to some extent, many issues like severity of the conditions, effect on surface mechanical properties, subsurface damage and phase transformation zone size have not been still fully addressed. Comprehensive understanding of these aspects will help in choosing better sandblasting conditions and also to improve the microstructural design of the materials for long term performance of the restorations so that clinical failures can be avoided or delayed. In this thesis, the effect of sandblasting on 3 mol% yttria stabilized zirconia (3Y-TZP) with different grain sizes has been studied under different sandblasting conditions. Additionally, nanocomposites formed by adding multiwall carbon nanotubes (0.5-2 vol. %) to 3Y-TZP matrix have been also studied. Initially, the study has been focused in the mechanical properties and hydrothermal degradation resistance of nanometric grain size 3Y-TZP and zirconia multiwall carbon nanotubes nanocomposites (3YTZP-MWCNT). Nanometric grain size 3Y-TZP (90-150 nm) produced by spark plasma sintering have slightly lower toughness compared to standard zirconia with grain size 300 nm. Adding multiwall carbon nanotubes improve the indentation fracture toughness nearly 15% compared to monolithic materials. Elastic modulus hardly changes while hardness decreases slightly for 2 vol.% nanotubes. The materials were subjected to sandblasting using two particle sizes, two pressures and two impact angles, After sandblasting the materials were analyzed looking for roughness, phase transformation and damage. In addition the change in mechanical properties and in hydrothermal degradation resistance induced by sandblasting was evaluated. It has been found that increasing particle size and pressure increases surface roughness. The bi-axial strength of zirconia has been studied only in standard 300 nm grain size 3Y-TZP. The main result has been to show that at impact angle of 90º the biaxial strength increases when sandblasted with 110 um particles while it decreases with 250 um particles. On the other hand, the strength slightly increases when sandblasted under an impact angle of 30° irrespective of the particle size. By using nanoindentation it is shown that mild sandblasting conditions (110 um particle size, 2 bars pressure) have no effect on the surface mechanical properties such as, elastic modulus and contact hardness. A model based on the formation of residual compressive stresses is presented in order to explain the indentation the shorter length of the indentation cracks in sandblasted material as well as to rationalize the increase in strength of sandblasted material under mild sandblasted conditions. The microstructural change induced by sandblasting near the surface consists of: i) a thin layer of plastically deformed grains; ii) phase transformation; and iii) occasional microcracking. The fraction of monoclinic volume fraction induced after sandblasting under the studied conditions is of about 10-15%, and with transformation up to a depth of about 10-13 um. Finally it is shown that in sandblasted conventional 3Y-TZP, the kinetics of hydrothermal degradation are slower than in the starting material.
Sjögren, Petteri. "Randomised clinical trials and evidence-based general dentistry /." Linköping : Univ, 2004. http://www.bibl.liu.se/liupubl/disp/disp2004/med865s.pdf.
Full textSoto, Susana. "Information in dentistry : patterns of communication and use." Thesis, University of Sheffield, 1992. http://etheses.whiterose.ac.uk/2955/.
Full textMandy, Philip John. "The nature and status of chiropody and dentistry." Thesis, University of Sussex, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300753.
Full textArheiam, A. "The use of diet diaries in clinical dentistry." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3008005/.
Full textBusto, Robert Alexander. "Reaching Special Populations in Dentistry with General Anesthesia." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu158798466339008.
Full textParanjpe, Avina. "Mechanisms and prevention of material toxicities in dentistry." Diss., Restricted to subscribing institutions, 2007. http://proquest.umi.com/pqdweb?did=1472130861&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Full textOliveira, Deise Cruz. "Minimally invasive dentistry approach in dental public health." Thesis, University of Iowa, 2011. https://ir.uiowa.edu/etd/1047.
Full textUmeri, Andrea. "Study of Zirconia's ageing for applications in dentistry." Doctoral thesis, Università degli studi di Trieste, 2010. http://hdl.handle.net/10077/3446.
Full textZirconia based materials have been widely used in construction of dental prosthesis because of their mechanical and aesthetical properties and a lot of money have been invested in their development, but no one of the producers considered the aging of zirconia. In this job have been demonstrated, with Raman spectroscopy, the low temperature degradation of zirconia and has been investigated the residual stress in zirconia-alumina composites at room temperature and in open-air after 8 years of aging, then have been investigated the phase trasformation of tetragonal zirconia into monocline form of pure zirconia and alumina-zirconia composites tested in water with a thermal fatigue cycle between 5°C and 55°C. A partial solution of the problem is proposed. Atomic Force Microsopy and Near-field Scanning Optical Microscopy techniques have been tested as method of investigation and validation of the results.
I materiali a base di zirconia trovano vasto impiego nella realizzazione di protesi dentali grazie alle loro proprietà meccaniche ed estetiche e molti soldi sono stati investiti nel loro sviluppo, ma nessuno dei produttori ha considerato il fenomeno di invecchiamento della zirconia. In questo lavoro è stato dimostrato, attraverso l‘impiego della spettroscopia Raman, il degrado a bassa temperatura della zirconia ed è stato analizzato lo stato tensionale interno in compositi allumina-zirconia mantenuti a temperatura ambiente in aria per 8 anni; a seguire è stata analizzata la trasformazione di fase da tetragonale a monoclino della zirconia in campioni sia di zirconia pura che in campioni di composito alumina-zirconia, testati in acqua e sottoposti ad un ciclo di fatica termica tra 5°C e 55°C. Viene anche proposto un metodo corretivo del problema. La microscopia a forza atomica e la microscopia ottica in campo prossimo sono state testate come strumento di verifica e validazione dei dati ottenuti.
XXII Ciclo
1980
Frassetto, Andrea. "Nanostructural analysis of the adhesive interface in dentistry." Doctoral thesis, Università degli studi di Trieste, 2014. http://hdl.handle.net/10077/9969.
Full textThe subject of this thesis is the stability of the adhesive interface in dentistry. Success in adhesive dentistry means long lasting restorations. However, there is substantial evidence that this ideal objective is not achieved. Current research in this field aims at increasing the resin-dentin bond durability. This doctoral research examines the fundamental processes responsible for the aging mechanisms involved in the degradation of resin-bonded interfaces, as well as some potential approaches to prevent and counteract this degradation. Resin-dentin bond degradation is a complex process that is not completely understood, involving the hydrolysis of both the resin and the collagen component of the hybrid layer. The hydrophilic and acidic characteristics of current dentin adhesives have made hybrid layers highly prone to water sorption, which causes polymer degradation and results in decreased resin-dentin bond strength over time. These unstable polymers inside the hybrid layer may result in an incomplete encapsulation of collagen fibers, which become vulnerable to mechanical and hydrolytical fatigue, as well as degradation by host-derived proteases with collagenolytic activity. These enzymes, such as matrix metalloproteinases (MMPs) and cysteine cathepsins, have a crucial role in the degradation of type I collagen, the organic component of the hybrid layer. The first part of this thesis aims to review the current knowledge regarding adhesion to the tooth substrate (Chapter 1), focusing on the fundamental processes that are responsible for the degradation of the adhesive interface (Chapter 2). Since the permeability of adhesives to water is particularly evident in simplified adhesive formulations, the research activity was focused on self-etch and universal adhesive systems’ behavior. Thus, the research study reported in Chapter 3 showed that the bond strength and nanoleakage expression of two-step and one-step self-etch tested bonding systems were affected by storage for 6 month and 1 year in artificial saliva. Although it is generally accepted that the permeability of adhesives to water is particularly evident in simplified adhesive formulations, the stability over time was not related to the number of steps of bonding systems, but to their chemical formulations. The performance of a new universal (or multi-mode) adhesive system through storage in artificial saliva was also investigated. The original results presented in Chapter 4 found that improved bonding effectiveness of the tested universal adhesive system on dentin was obtained when the adhesive was applied with the self-etch approach. Indeed, the etch-and-rinse approaches tested (both on wet and dry dentin) resulted in immediate bond strength comparable to the self-etch mode but expedited long-term aging resulted in reduced bond strength and increased nanoleakage expression, irrespective of dentin wetness. Moreover, the results of the zymographic analysis showed evident changes in dentinal MMP-2 and -9 enzyme activities after the application of the tested adhesives, revealing differences in the extent of enzyme activation. These findings exhibit that the activation of endogenous MMPs is not related to the adhesive system or the strategy employed. Thus, regardless of the approach and the material used in bonding procedures, a stable and durable bond is not achieved. Therefore, experimental strategies that aim to enhance the adhesive interface, particularly improving the durability of the resin-dentin bond strength by inhibiting intrinsic collagenolytic activity and increasing the resistance of dentin collagen matrix to enzymatic degradation are needed. The last part of the thesis is focused on both the strategies to inhibit the proteolytic and collagenolytic activity of the endogenous proteases and the methods to increase the mechanical strength of collagen network and its resistance to enzymatic degradation (Chapter 5). Chlorhexidine (CHX) has been used as a non-specific MMP inhibitor to prevent degradation of hybrid layers. However, CHX is water-soluble and may leach out of hybrid layers, compromising its long-term anti-MMP effectiveness. An entirely different approach is to treat the acid-etched dentin containing activated matrix-bound MMPs with cross-linking agents that inactivate the catalytic site of proteases. In particular, the ability of a cross-linker agent, 1-ethyl-3-(3-dimethylamino-propyl) carbodiimide (EDC), to prevent collagen degradation was evaluated under occlusal cycle loading. Previous research successfully utilized EDC to increase the durability of resin-dentin bonds by increasing the mechanical properties of the collagen matrix; however, the 1 to 4 hrs required for that procedure was clinically unacceptable. For this reason, the purpose of the last part of the research, presented in Chapter 6, was to evaluate the ability of 0.5 M EDC short-time (1 min) pre-treatment to improve the stability of demineralized dentin collagen matrices by quantifying the release of telopeptide fragments over time. The results showed that EDC application for 1 min may be a clinically relevant and effective means for stabilizing the collagen network not only by strengthening the fibrils, but also by reducing the enzymatic degradation rate. Thus, dentin collagen reinforcement and strengthening through EDC cross-linking might be of importance to improve the bond strength and structural integrity of the resin-dentin interface over time against the enzymatic and hydrolytic degradation.
La tesi qui presentata riguarda la stabilità dell'interfaccia adesiva in odontoiatria. Il successo delle moderne terapie conservative è rappresentato dalla longevità dei restauri adesivi. Tuttavia, vi è una sostanziale evidenza che questo obiettivo ideale non sia raggiunto. La stabilità dell’interfaccia adesiva dipende dalla formazione di uno strato ibrido, compatto e omogeneo, durante l’impregnazione del substrato dentinale da parte dei monomeri adesivi. Poiché lo strato ibrido rappresenta un’entità complessa, in cui interagiscono componenti biologiche diverse (matrice dentinale collagenica e cristalli d’idrossiapatite residui) e non (monomeri resinosi e solventi), i fenomeni d’invecchiamento interessano in maniera sinergica sia la porzione resinosa che quella dentale. L’articolato processo che porta alla degradazione dell’interfaccia adesiva coinvolge infatti la componente resinosa, attraverso l’idrolisi della resina negli spazi interfibrillari, e quella organica, attraverso la disorganizzazione delle fibre collagene dovuta ad un incompleto incapsulamento delle stesse, nonché alla degradazione da parte di proteasi intrinseche con attività collagenolitica. È stato dimostrato come questi enzimi, le metalloproteinasi della matrice (MMP) e le catepsine, abbiano un ruolo cruciale nella degradazione del collagene di tipo I, la principale componente organica dello strato ibrido. Inoltre le caratteristiche idrofile e acide degli attuali sistemi adesivi dentinali hanno reso lo strato ibrido molto suscettibile all'assorbimento di acqua, comportando, attraverso l’idrolisi, la degradazione dello stesso e andando così a contribuire ad una diminuzione della forza di legame nel tempo. Attualmente l’interesse della comunità scientifica mira ad aumentare la durata del legame adesivo con il substrato dentinale. Dopo un’attenta analisi delle attuali conoscenze riguardanti adesione al substrato dentale (Capitolo 1), la prima parte della tesi si propone di valutare i processi fondamentali che sono responsabili della degradazione dell'interfaccia adesiva (Capitolo 2). Poiché la permeabilità all’acqua degli adesivi è particolarmente evidente nelle formulazioni semplificate, l'attività di ricerca si è concentrata sull’analisi del comportamento dei sistemi adesivi self-etch e dei recenti sistemi adesivi universali. I risultati riportati nel Capitolo 3 ha dimostrato come la forza di legame e l’espressione del nanoleakage dei sistemi adesivi self-etch two-step e one-step testati sia negativamente influenzata dall’invecchiamento in saliva artificiale per 6 mesi e 1 anno. Sebbene sia generalmente accettato che la permeabilità degli adesivi all'acqua è particolarmente evidente in formulazioni di adesivi semplificati, la stabilità nel tempo non è stata correlata al numero di passaggi dei sistemi adesivi, bensì alle loro composizioni chimiche. Sono state in seguito analizzate anche le prestazioni di un nuovo sistema adesivo universale (o multimodale). I risultati presentati nel Capitolo 4 hanno stabilito una migliore efficienza adesiva del sistema universale, testato sul substrato dentinale, quando l'adesivo è stato applicato con l'approccio self-etch. Infatti, la tecnica etch-and-rinse, testata sia su dentina umida che secca, ha comportato una forza di adesione immediata paragonabile alla modalità self-etch, ma a tempi di invecchiamento incrementali si è evidenziata una diminuzione della forza di legame e una maggiore espressione del nanoleakage, a prescindere dalla condizione di umidità dentinale. Inoltre, i risultati dell'analisi zimografica hanno mostrato evidenti variazioni dell’attività enzimatica delle metalloproteinasi MMP-2 e -9 dopo l'applicazione degli adesivi testati. Questi risultati dimostrano come l'attivazione delle MMP endogene non sia correlata al sistema adesivo o alla strategia adottata. Ne evince che, indipendentemente dal metodo e dal materiale utilizzato nelle procedure adesive, non si è in grado di stabilire un legame affidabile e duraturo. Pertanto si avverte l’esigenza di strategie sperimentali che mirino a migliorare la stabilità dell’interfaccia adesiva, in particolare incrementando la durata della forza di legame in dentina inibendo l'attività collagenolitica intrinseca e aumentando la resistenza del collagene alla degradazione enzimatica. L'ultima parte della tesi è focalizzata quindi sulle strategie per inibire l'attività proteolitica e collagenolitica delle proteasi endogene e sui metodi per aumentare la resistenza meccanica del collagene alla degradazione enzimatica (Capitolo 5). Un potente agente antibatterico, la clorexidina (CHX), è stato usato come inibitore non specifico delle MMP al fine di impedire la degradazione dello strato ibrido. Tuttavia la CHX, essendo solubile in acqua, può dissolversi nello strato ibrido, compromettendo la sua efficacia anti-MMP a lungo termine. Un approccio completamente diverso è quello di trattare la dentina mordenzata con agenti cross-linker. In particolare, simulando il carico occlusale, è stata valutata la capacità di un agente cross-linker, l’1-etil-3-(3-dimetilammino-propil) carbodiimmide (EDC), per prevenire la degradazione del collagene. Precedenti ricerche hanno utilizzato con successo l’EDC con lo scopo di aumentare la durata dell’interfaccia adesiva, aumentando le proprietà meccaniche della matrice di collagene; tuttavia, il tempo necessario (da 1 a 4 ore) richiesto per tali procedure è clinicamente inaccettabile. Per questo motivo, lo scopo dell’ultima parte della ricerca, presentata nel Capitolo 6, è stato quello di valutare la capacità di 0,5 M EDC nel breve periodo di pretrattamento (1 min), andando a quantificare il rilascio di frammenti di telopeptidi di collagene nel corso del tempo. I risultati hanno dimostrato che l'applicazione di EDC per 1 min può essere un approccio clinicamente rilevante ed efficace nello stabilizzare il collagene, non solo rafforzando le fibrille, ma anche riducendo la velocità di degradazione enzimatica. Di conseguenza, l’utilizzo di questo cross-linker può garantire una valida strategia per migliorare la forza di legame e l'integrità strutturale dell'interfaccia adesiva nel tempo contro l’attività enzimatica intrinseca del collagene e la degradazione idrolitica.
XXVI Ciclo
1985
Isaksson, Anders, and Michael Graham. "RoDent : Robotic Dentistry : Computer aided dental implant positioning system." Thesis, Halmstad University, School of Information Science, Computer and Electrical Engineering (IDE), 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-1559.
Full textA study was carried in conjunction with the Orthodontic department at Halmstad General Hospital in Sweden to investigate the possibility of reducing cost and manufacture time of dental implant drill guides.
The current system involves sending a digital image in STL format to the Materialise factory in Belgium where information of the position of dental implants is translated onto a moulded mouthpiece. Drill guides are placed in the mouth piece which is then returned to the surgeon. The mouthpiece complete with drill guides is then placed in the patients mouth and used as a guide for the implant drill holes. The cost of 10000 sek and a turnaround time of 2 weeks gave rise to the need for a faster and cheaper solution.
A new mouthpiece was designed comprising of a solid cube which could be clearly seen on the x-ray. Linearisation of the cube faces is used to find a reference point from which to drive a 5 axis drilling platform. The mouthpiece is placed in the drill platform which is driven by stepper motors which in turn are controlled by a microcontroller. Co-ordinates are entered via a PC interface. The PC software then translates these co-ordinates into motor steps which are sent to the microcontroller. The drill platform then positions the mouthpiece in order to drill guide holes for the dental implants.
The study showed that the machine design gave an acceptable degree of accuracy and repeatability. Further enhancements could be made by automating the detection of the cube using image analysis techniques. The study was also limited by the lack of graphical and geometrical data concerning the position of the implant. For the purpose of this study the co-ordinates for the implants guides is entered by hand.
It was concluded that further software and hardware enhancement would be needed before the application could be developed commercially.
Gray, Crawford F. "The development of magnetic resonance imaging for implant dentistry." Thesis, University of Glasgow, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250064.
Full textAlkafaji, Zina. "Review of pediatric dentistry oral sedation outcomes and influences." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/59960.
Full textDentistry, Faculty of
Graduate