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1

Nainar, S. M. Hashim, and Deborah A. Redford-Badwal. "Survey of Dental Prophylaxes Rendered by Pediatric Dentists in New England." Journal of Contemporary Dental Practice 5, no. 4 (2004): 14–22. http://dx.doi.org/10.5005/jcdp-5-4-14.

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Abstract Background The objective of this anonymous postal survey was to assess the provision of dental prophylaxis by pediatric dentists in New England. Methods The questionnaire survey was sent by first class mail in September, 2001 to all 217 American Academy of Pediatric Dentistry (AAPD) members in active private practice in the six New England States of Connecticut, Massachusetts, Maine, New Hampshire, Rhode Island, and Vermont. A self-addressed, stamped envelope was provided to facilitate the returned response. Results The survey had a response rate of 70%. Most practitioners (93%) routinely recommended dental prophylaxis for their recall patients. The proportion of practitioners who considered the following indications for recommending dental prophylaxis was: plaque, stain, and/or calculus removal – 99%; caries prevention – 75%; prior to topical fluoride application - 82%; prior to sealant application - 58%; and for behavioral modification - 68%. Almost two thirds of the practitioners (62%) defined dental prophylaxis as referring to both rubber cup pumice prophylaxis as well as to toothbrush prophylaxis. However, only one in four practitioners (26%) had modified her/his clinical practice to substitute toothbrush prophylaxis in lieu of rubber cup pumice prophylaxis. Conclusion Pediatric dentists in New England routinely provide dental prophylaxis to their recall patients. Citation Nainar SMH, Redford-Badwal DA. Survey of Dental Prophylaxes Rendered by Pediatric Dentists in New England . J Contemp Dent Pract 2004 November;(5)4:014-022.
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Auvil, James D. "News about Dental Prophylaxis." Journal of Veterinary Dentistry 7, no. 3 (September 1990): 14–15. http://dx.doi.org/10.1177/089875649000700301.

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The most important measure in the treatment of inflammation of the gums is the removal of the concretions from the teeth, and next the arousing in the mind of the patient an active determination to keep them clean in the future. These two measures are absolutely necessary for success; nothing can be accomplished unless they are scrupulously carried out. The removal of these concretions in such a manner as to assure success is, however, one of the most difficult operations in dental surgery. Another very serious difficulty standing in the way of success is the very slack and inefficient notions that have been held in regard to it by the profession at large. When dentists learn to regard this operation as equal in importance to, and requiring as much thoroughness as, the filling of teeth, and when they apply themselves with the same diligence to acquiring the necessary dexterity in its performance, they will be rewarded with success; without this, success in the treatment of this disease cannot be attained.
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Simmons, N. A., A. P. Ball, R. A. Cawson, S. J. Eykyn, R. Feldman, W. A. Littler, D. A. Mcgowan, C. M. Oakley, and D. C. Shanson. "Dental prophylaxis for endocarditis." Lancet 340, no. 8831 (November 1992): 1353. http://dx.doi.org/10.1016/0140-6736(92)92537-p.

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Sambrook, Paul. "Dental note: Antimicrobial prophylaxis for dental surgery." Australian Prescriber 40, no. 6 (December 4, 2017): 230. http://dx.doi.org/10.18773/austprescr.2017.074.

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DeRosa, Alicia, Bethany A. Wattengel, Michael T. Carter, John A. Sellick, and Kari A. Mergenhagen. "An Evaluation of Antimicrobial Prophylaxis for Dental Procedures at a Veterans Healthcare System; A Role for Senior Care Pharmacists?" Senior Care Pharmacist 35, no. 12 (December 1, 2020): 567–72. http://dx.doi.org/10.4140/tcp.n.2020.567.

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OBJECTIVE: The primary objective of this study was to determine the prevalence of appropriate use of antibiotics before a dental procedure.<br/> DESIGN: Retrospective cohort study.<br/> SETTING: Veterans Healthcare Systems.<br/> PARTICIPANTS: Veterans who filled outpatient prescriptions for antimicrobial dental prophylaxis at the Veterans Administration Western New York Healthcare System from December 1, 2017, through October 1, 2019.<br/> INTERVENTIONS: None.<br/> MAIN OUTCOME MEASURES: Use of antibiotic dental prophylaxis was deemed appropriate if in accordance with guideline recommendations. Descriptive statistics were used to summarize data.<br/> RESULTS: A total of 130 veterans receiving antibiotics for dental prophylaxis were included in this evaluation. Of those who were included, only 16.9% received appropriate antibiotic dental prophylaxis. Patients with a prosthetic joint were significantly more likely to be inappropriately prescribed antibiotics for dental prophylaxis. Approximately 87% of patients who were inappropriately prescribed antibiotic prophylaxis had prosthetic joints (P < .0001).<br/> CONCLUSION: Most antibiotics for dental prophylaxis are prescribed inappropriately. The large amount of inappropriately used antibiotics in this study highlights the need for dental stewardship in our veteran population. Antibiotics for dental prophylaxis therefore represent an important stewardship target in the outpatient setting. This may be an ideal opportunity for senior care pharmacists to intervene upon.
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DeRosa, Alicia, Bethany A. Wattengel, Michael T. Carter, John A. Sellick, and Kari A. Mergenhagen. "An Evaluation of Antimicrobial Prophylaxis for Dental Procedures at a Veterans Healthcare System; A Role for Senior Care Pharmacists?" Senior Care Pharmacist 35, no. 12 (December 1, 2020): 567–72. http://dx.doi.org/10.4140/tcp.n.2020.567.

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OBJECTIVE: The primary objective of this study was to determine the prevalence of appropriate use of antibiotics before a dental procedure.<br/> DESIGN: Retrospective cohort study.<br/> SETTING: Veterans Healthcare Systems.<br/> PARTICIPANTS: Veterans who filled outpatient prescriptions for antimicrobial dental prophylaxis at the Veterans Administration Western New York Healthcare System from December 1, 2017, through October 1, 2019.<br/> INTERVENTIONS: None.<br/> MAIN OUTCOME MEASURES: Use of antibiotic dental prophylaxis was deemed appropriate if in accordance with guideline recommendations. Descriptive statistics were used to summarize data.<br/> RESULTS: A total of 130 veterans receiving antibiotics for dental prophylaxis were included in this evaluation. Of those who were included, only 16.9% received appropriate antibiotic dental prophylaxis. Patients with a prosthetic joint were significantly more likely to be inappropriately prescribed antibiotics for dental prophylaxis. Approximately 87% of patients who were inappropriately prescribed antibiotic prophylaxis had prosthetic joints (P < .0001).<br/> CONCLUSION: Most antibiotics for dental prophylaxis are prescribed inappropriately. The large amount of inappropriately used antibiotics in this study highlights the need for dental stewardship in our veteran population. Antibiotics for dental prophylaxis therefore represent an important stewardship target in the outpatient setting. This may be an ideal opportunity for senior care pharmacists to intervene upon.
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Bakhsh, Abdulaziz A., Husain Shabeeh, Francesco Mannocci, and Sadia Ambreen Niazi. "A Review of Guidelines for Antibiotic Prophylaxis before Invasive Dental Treatments." Applied Sciences 11, no. 1 (December 30, 2020): 311. http://dx.doi.org/10.3390/app11010311.

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Bacteraemia associated with invasive dental treatments can propagate infective endocarditis in high-risk cardiac patients. Over the past decade, antibiotic prophylaxis before dental treatment has been questioned. This review aims to compare the variations between the UK, European and American antibiotic prophylaxis guidelines before dental treatments. Antibiotic prophylaxis guidelines by the National Institute for Health and Care Excellence (NICE)—Clinical Guideline 64, Scottish Dental Clinical Effectiveness Programme (SDCEP), American Heart Association (AHA), European Society of Cardiology (ESC), European Society of Endodontology (ESE) and Belgian Health Care Knowledge Centre (KCE) position statements were compared regarding the indications, high-risk patients and prophylaxis regimens before dental treatments. In the United Kingdom, the NICE—Clinical Guideline 64 and SDCEP—Implementation Advice do not advise the prescription of prophylactic antibiotics for the majority of high-risk cardiac patients undergoing routine dental treatments. On the contrary, the AHA, ESC and KEC recommend the prescription of antibiotics prior to invasive dental procedures in high-risk cardiac individuals. The ESE also indicates prophylaxis before endodontic procedures for patients with other conditions, including impaired immunologic function, prosthetic joint replacement, high-dose jaw irradiation and intravenous bisphosphonates. Among these guidelines, there are variations in antibiotic prophylaxis regimens. There are variations regarding the indications and antibiotic prophylaxis regimens before invasive dental treatments among these available guidelines.
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Suda, Kj, Sruthi Adimadhyam, Greg Calip, Susan Rowan, Alan E. Gross, Rose Perez, Ronald Hershow, Jessina C. McGregor, and Charlesnika Evans. "1630. Antibiotics Prescribed for Infection Prophylaxis Prior to Dental Procedures Are Frequently Unnecessary in the United States." Open Forum Infectious Diseases 5, suppl_1 (November 2018): S42. http://dx.doi.org/10.1093/ofid/ofy209.100.

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Abstract Background Antibiotics are recommended prior to certain dental procedures (“antibiotic prophylaxis”) in patients with select comorbidities to prevent serious distant site infections. Our objective was to assess the appropriateness of antibiotic prophylaxis by dentists using Truven, a national integrated medical, dental, and prescription (Rx) claims database of 350 commercial plans. Methods Cross-sectional study of 8.7 million adult dental visits in 2015. Antibiotic prophylaxis was defined as Rx with &lt;3 days supply dispensed within 7 days before a dental visit. Medical diagnoses were evaluated in medical/hospital claims from 2009 to 2015. Patients with hospitalizations and infection diagnoses 14 days prior to the Rx date were excluded. Appropriate antibiotic prophylaxis was defined as a dental visit with a procedure that manipulated the gingiva/tooth periapex in patients with an appropriate cardiac diagnosis. Chi Square and logistic regression were applied. Results In 2015, 30,726 antibiotics were prescribed for dental infection prophylaxis for 21,986 patients (mean age=58.6 + 15.0 years; 55.9% female). Amoxicillin (68.5%) and clindamycin (14.7%) were most common. 29,879 dental visits were associated with 69,639 dental codes ([CDTs]; range 1–14 CDTs/visit). Most dental visits were diagnostic (65.9% of visits with &gt;1 diagnostic CDT), preventative (53.0%), and restorative (11.2%). 98.4% of dental visits had an appropriate CDT for antibiotic prophylaxis. Comorbidities include orthopedic implants (45.4%) and cardiac diagnoses at the highest risk of infective endocarditis (22.2%). Per guidelines, 78.0% of dental visits with antibiotic prophylaxis were inappropriate. Amoxicillin was more likely to be inappropriate than other agents (OR=1.65; 95% CI: 1.55–1.76). Orthopedic implants (OR=3.35; 95% CI: 3.14–3.56), tooth implant procedures (OR=3.30; 95% CI: 2.48–4.39), females (OR=1.35; 95% CI: 1.27–1.43) and the western US (OR=1.22; 95% CI: 1.09–1.36) were associated with inappropriate prescribing. Conclusion Antibiotic prophylaxis is prescribed for indicated dental procedures, but is not appropriately limited to patients with cardiac diagnoses per guidelines. Implementing antimicrobial stewardship efforts in dental practices may be an opportunity to improve antibiotic prescribing for infection prophylaxis. Disclosures J. C. McGregor, Merck: Grant Investigator, Research grant.
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Pokharel, Prenit Kumar, and Shrijana Chapagain. "Awareness among the Dental students and Dental Interns of Kantipur Dental College and Hospital regarding Antibiotics Prophylaxis for Infective Endocarditis." Journal of College of Medical Sciences-Nepal 15, no. 2 (June 30, 2019): 112–18. http://dx.doi.org/10.3126/jcmsn.v15i2.22162.

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Background: Infective Endocarditis is relatively a rare disease and is believed to be caused by the vegetative growth on the previously damaged or congenitally malformed cardiac valves or endocardium. Several factors determines that the dentist practicing prophylaxis measures, the foremost important one is the knowledge which is taught to them during dental school, which is the main reason to conduct this study to test the awareness among the dental students of Kantipur Dental College and Hospital, Kathmandu regarding the prophylaxis guideline awareness. Methods: BDS Third, Fourth, Fifth year students and Dental Interns of Kantipur Dental College and Hospital were asked to fill the self-answered questionnaires. The questions were divided into two parts each part containing ten questions each. The first part was to access the knowledge of participants regarding the cardiac conditions that require antibiotics prophylaxis, the second part was to access the knowledge of participants regarding the dental procedures that requires antibiotics prophylaxis. Results: Thirty two percentage of our participants responded that forceps extraction does not require antibiotics prophylaxis which is not true as per AHA guideline, so the participants should be taught regarding the risk of forceps extraction leading to infective endocarditis if the prophylaxis is not administered. We postulated that majority of the Dental Students and Interns have heard about AHA 2007 guideline and will follow it when necessary. Conclusions: The participants who are the Dental Students and Dental Interns in a Dental School at Kathmandu, Nepal will be practicing Dentistry in near future, the knowledge they acquire during their learning period will help them to prevent the Infective endocarditis among the risk population whom they will be treating in near future. Measures should be taken to prevent the incidence of Infective Endocarditis with dental origin.
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Daly, Christopher G. "Antibiotic prophylaxis for dental procedures." Australian Prescriber 40, no. 5 (October 3, 2017): 184–88. http://dx.doi.org/10.18773/austprescr.2017.054.

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Kuprina, I. V., E. A. Kiseleva, T. M. Grishkyan, A. M. Grishkyan, K. S. Kyseleva, and D. S. Kiselev. "Region prophylaxis of dental fluorosis." Clinical Dentistry, no. 2 (2020): 130–35. http://dx.doi.org/10.37988/1811-153x_2020_2_130.

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12

Ballard, Craig, Robert M. Mowers, and Mirta Millares. "Antibiotic Prophylaxis in Dental Procedures." DICP 24, no. 1 (January 1990): 41–43. http://dx.doi.org/10.1177/106002809002400109.

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13

Lockhart, Peter B. "Antibiotic Prophylaxis for Dental Procedures." Circulation 126, no. 1 (July 3, 2012): 11–12. http://dx.doi.org/10.1161/circulationaha.112.115204.

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14

Davies, R. "Antibiotic prophylaxis in dental practice." BMJ 307, no. 6913 (November 6, 1993): 1210–11. http://dx.doi.org/10.1136/bmj.307.6913.1210-d.

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15

Sampson, Chris. "Is routine dental prophylaxis effective?" Evidence-Based Dentistry 11, no. 1 (March 2010): 16–17. http://dx.doi.org/10.1038/sj.ebd.6400704.

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Cawson, R. A. "Antibiotic prophylaxis for dental treatment." BMJ 304, no. 6832 (April 11, 1992): 933–34. http://dx.doi.org/10.1136/bmj.304.6832.933.

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17

Altun Demircan, Şerife. "Infective endocarditis prophylaxis." Journal of Cardiology & Cardiovascular Surgery 1, no. 2 (June 28, 2023): 25–27. http://dx.doi.org/10.51271/jccvs-0007.

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Infective endocarditis is a serious infection disease which has a mortality rate of 30% in the first year in our country. Today in the majority of the cases, infective endocarditis is thought to develop after transient bacteremia of bacteria in the oral microbiota during daily procedures such as toothbrushing. Good oral hygiene and dental care are more effective than antibiotic prophylaxis. In recent guidelines, antibiotic prophylaxis is recommended for the high-risk group for the development of infective endocarditis and for dental procedures with bleeding.
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Singanal, Sharanabasappa, Anand R. Kanaki, and Bindushree A. R. "Knowledge and practice of antibiotic prophylaxis for infective endocarditis among dental students." International Journal of Basic & Clinical Pharmacology 6, no. 9 (August 22, 2017): 2167. http://dx.doi.org/10.18203/2319-2003.ijbcp20173738.

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Background: Infective endocarditis (IE) is a microbial infection of the valves and endocardium of the heart. IE is difficult to treat and has a poor prognosis. Dentists play a major role in preventing IE in susceptible patients. In this study, we evaluate knowledge and practice of antibiotic prophylaxis for IE among dental students, interns and PGs at S. N. Dental College, Kalaburagi.Methods: A cross-sectional study was done by survey using questionnaire. Questionnaire was distributed to 159 dental students, interns and PGs at S. N. Dental College, Kalaburagi. Questionnaire included questions regarding to demographic information and knowledge and practice of the participants about antibiotic prophylaxis for IE.Results: Out of 159 participants 135 provided the response, giving a response rate of 85%. Overall, average of 52.7% of the participants had a good level of knowledge regarding the cardiac conditions that require antibiotic prophylaxis. Participants also had better knowledge regarding dental procedures that require prophylaxis with an average of 75.7%. But only 37.2% prescribed correct drug, dosage and regime of antibiotic prophylaxis.Conclusions: The level of knowledge and practice about antibiotics prophylaxis of IE amongst dental students, interns and PGs at the study site was not at an acceptable level. Awareness is essential because of the cardiac risks associated with the lack of appropriate prophylaxis. Up-to-date and accurate knowledge is mandatory for all dental students, interns and PGs who see and treat patients on a daily basis. This study emphasized the need for continuous education and for formal inclusion of the guidelines in the student’s curriculum.
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Goff, Debra A., Julie E. Mangino, Andrew H. Glassman, Douglas Goff, Peter Larsen, and Richard Scheetz. "Review of Guidelines for Dental Antibiotic Prophylaxis for Prevention of Endocarditis and Prosthetic Joint Infections and Need for Dental Stewardship." Clinical Infectious Diseases 71, no. 2 (November 15, 2019): 455–62. http://dx.doi.org/10.1093/cid/ciz1118.

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Abstract Dentists prescribe 10% of all outpatient antibiotic prescriptions, writing more than 25.7 million prescriptions per year. Many are for prophylaxis in patients with prosthetic joint replacements; the American Dental Society states that “in general,” prophylactic antibiotics are not recommended to prevent prosthetic joint infections. Orthopedic surgeons are concerned with the risk of implant infections following a dental procedure and, therefore, see high value and low risk in recommending prophylaxis. Patients are “stuck in the middle,” with conflicting recommendations from orthopedic surgeons (OS) and dentists. Unnecessary prophylaxis and fear of lawsuits amongst private practice dentists and OS has not been addressed. We review The American Heart Association/American College of Cardiology, American Dental Association, and American Association of Orthopedic Surgeons’ guidelines on dental antibiotic prophylaxis for the prevention of endocarditis and prosthetic joint infections. We provide experience on how to engage private-practice dentists and OS in dental stewardship using a community-based program.
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Chirouze, C., B. Hoen, and X. Duval. "Infective endocarditis prophylaxis: moving from dental prophylaxis to global prevention?" European Journal of Clinical Microbiology & Infectious Diseases 31, no. 9 (February 23, 2012): 2089–95. http://dx.doi.org/10.1007/s10096-012-1564-3.

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Duarte, Ana Vitória Machado, Beatriz Soares Leitão Barbosa, Giovana Gisele Costa Oliveira, Júlia Maria de Sá Borges, Kamila Gregório da Costa Sousa, Milleny Ribeiro da Silva Cavalcante, Pedro Lucas Rocha dos Santos Araújo, Thales Amon Pereira Duarte Rocha, Felipe Cardoso Rodrigues Vieira, and Stanley Keynes Duarte dos Santos. "Clinical Relevance of Antibiotic Prophylaxis in Dental Surgical Procedures: A Systematic Review." Journal of Advances in Medicine and Medical Research 35, no. 21 (September 11, 2023): 57–65. http://dx.doi.org/10.9734/jammr/2023/v35i215212.

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Background: Antibiotic prophylaxis is a procedure performed with the use of antibiotics to prevent the patient from contracting some type of infection during surgical procedures. Aim: To analyze the clinical relevance of using antibiotic prophylaxis before dental surgical procedures. Methods: This is a systematic review of the qualitative literature in the PubMed, LILACS and Medline databases, using the health descriptors "Antibiotic Prophylaxis", "Dentistry" and "Oral Surgical Procedures" and selected articles in English and Portuguese published between 2018 and 2022. Articles that did not follow the eligibility criteria and that did not address relevant data for the present study were excluded. Abstracts were also excluded; duplicate articles; review articles; meta-analysis and studies not related to dentistry. Results: After the research, considering the inclusion and exclusion criteria and thematic relevance, 15 articles were selected. Upon analysis, it was found that the effect of antibiotic prophylaxis in case of dental surgeries is small and may not be clinically relevant. Some improvement in postoperative symptoms in dental surgeries can be explained by the decrease in bacterial contamination of the surgical wound, and antibiotic prophylaxis is associated with a lower need for analgesic administration. Amoxicillin is considered the antibiotic of choice for antibiotic prophylaxis in clinical dental practice. In cases of penicillin allergy, clindamycin is often prescribed as a substitute of choice, with lower doses of clindamycin when given over shorter periods of time beneficial in relieving pain and reducing postoperative complications. Conclusion: Regarding the analyzed studies, it appears that the effect of antibiotic prophylaxis in cases of dental surgery may be small and not clinically relevant. In view of this, more studies on the clinical relevance of antibiotic prophylaxis in dental procedures should be carried out and more factors should be addressed in research to increase the scope of analysis.
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Gross, Alan E., Katie J. Suda, Jifang Zhou, Gregory Calip, Susan A. Rowan, Ronald Hershow, Rose Perez, Charlesnika T. Evans, and Jessina C. McGregor. "1895. Serious Antibiotic-Related Adverse Effects Following Unnecessary Dental Prophylaxis in the United States." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S56. http://dx.doi.org/10.1093/ofid/ofz359.122.

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Abstract Background Dentists prescribe 10% of outpatient antibiotics in the United States, with a significant portion of these being for prophylaxis. We previously found that 80% of prescriptions for prophylaxis prescribed prior to dental visits are unnecessary; however, the sequelae of these unnecessary antibiotics have not been characterized. Our objective was to assess the harms of unnecessary antibiotic prophylaxis using Truven, a national health claims database. Methods This was a retrospective cohort study of patients with dental visits from 2011 to 2015 linked to medical and prescription claims. Patients with commercial dental insurance without a hospitalization or extra-oral infection 14 days prior to antibiotic prophylaxis (≤2 days supply dispensed within 7 days before a dental visit) were assessed for inclusion. Patients with unnecessary antibiotic prophylaxis (defined as antibiotic prophylaxis in patients who both did not undergo a procedure that manipulated the gingiva/tooth periapex and did not have an appropriate cardiac diagnosis) were included and assessed for serious antibiotic-related adverse effects (AAE). The primary endpoint was the cumulative incidence of any AAE within 14 days post-prescription (composite of allergy, anaphylaxis, C. difficile infection, or ED visit). The secondary analyses were the cumulative incidence of each individual AAE and the risk difference of the primary endpoint between amoxicillin and clindamycin. Results Of the 168,420 dental visits with antibiotic prophylaxis, 136,177 (80%) were unnecessary and included for analysis. 3.8% of unnecessary prescriptions were associated with an AAE; primary and secondary endpoints are listed in the Table. ED visits (1.2%) and new allergies (2.9%) were most frequent. Clindamycin was associated with more AAE than amoxicillin (risk difference 322.1 per 1000 person-years, 95% CI: 238.5 - 405.8). Conclusion Even though antibiotic prophylaxis is prescribed for a short duration (≤2 days), it is not without risk. Since most AAE are diagnosed in medical settings, dentists may not be aware of these adverse effects. These data provide further impetus to decrease unnecessary prescribing of antibiotic prophylaxis prior to dental procedures. Disclosures All Authors: No reported Disclosures.
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Woods, RG. "Dental note: Antibiotics for surgical prophylaxis." Australian Prescriber 28, no. 2 (April 1, 2005): 41. http://dx.doi.org/10.18773/austprescr.2005.031.

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Lanza, Giovanna Lopes, Ana Luiza Rodrigues Gomes, Luiza Carvalho Lamounier Cardoso, Marcelo Ferreira Pinto Cardoso, and Giovanna Ribeiro Souto. "SUBCUTANEOUS EMPHYSEMA DUE TO DENTAL PROPHYLAXIS." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 134, no. 3 (September 2022): e91. http://dx.doi.org/10.1016/j.oooo.2022.01.064.

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Barton, L. L., and M. H. Rathore. "Dental Procedure Bacteremia and Antibiotic Prophylaxis." AAP Grand Rounds 12, no. 4 (October 1, 2004): 42–43. http://dx.doi.org/10.1542/gr.12-4-42.

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Kyle, Mark A., and B. Jean Hawkins. "The procedure for complete dental prophylaxis." Journal of Veterinary Dentistry 5, no. 3 (September 1988): 17–18. http://dx.doi.org/10.1177/089875648800500305.

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Gynther, Göran W., Per Åke Köndell, Lars-Erik Moberg, and Anders Heimdahl. "Dental implant installation without antibiotic prophylaxis." Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 85, no. 5 (May 1998): 509–11. http://dx.doi.org/10.1016/s1079-2104(98)90281-5.

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Dewire, Peter, Brian E. McGrath, and Corstiaan Brass. "Haemophilus Aphrophilus Osteomyelitis After Dental Prophylaxis." Clinical Orthopaedics and Related Research 363 (June 1999): 196???202. http://dx.doi.org/10.1097/00003086-199906000-00026.

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GOODSON, J. MAX, MICHAEL D. PALYS, ELIZABETH CARPINO, ELIZABETH O. REGAN, MICHAEL SWEENEY, and SIGMUND S. SOCRANSKY. "Microbiological changes associated with dental prophylaxis." Journal of the American Dental Association 135, no. 11 (November 2004): 1559–64. http://dx.doi.org/10.14219/jada.archive.2004.0082.

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Keenan, James R., and Analia Veitz-Keenan. "Antibiotic prophylaxis for dental implant placement?" Evidence-Based Dentistry 16, no. 2 (June 2015): 52–53. http://dx.doi.org/10.1038/sj.ebd.6401097.

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Oyer, C. E. "Hepatitis B prophylaxis in dental professionals." JAMA: The Journal of the American Medical Association 256, no. 23 (December 19, 1986): 3217b—3217. http://dx.doi.org/10.1001/jama.256.23.3217b.

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Oyer, Calvin E. "Hepatitis B Prophylaxis in Dental Professionals." JAMA: The Journal of the American Medical Association 256, no. 23 (December 19, 1986): 3217. http://dx.doi.org/10.1001/jama.1986.03380230041017.

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Brondani, Mario A. "Health Technology Assessment Fireside: Antibiotic Prophylaxis and Dental Treatment in Canada." Journal of Pharmaceutics 2013 (September 2, 2013): 1–9. http://dx.doi.org/10.1155/2013/365635.

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Objectives. This paper discusses the controversies surrounding the antibiotic prophylaxis preceding dental interventions within the following research question: how effective is dental antibiotic prophylaxis in preventing comorbidity and complications in those at risk? Methods. A synthesis of the available literature regarding antibiotic prophylaxis in dentistry was conducted under the lenses of Kazanjian’s framework for health technology assessment with a focus on economic concerns, population impact, social context, population at risk, and the effectiveness of the evidence to support its use. Results. The papers reviewed show that we have been using antibiotic prophylaxis without a clear and full understanding of its benefits. Although the first guideline for antibiotic prophylaxis was introduced in 1990, it has been revised on several occasions, from 1991 to 2011. Evidence-based clinical guidelines are yet to be seen. Conclusions. Any perceived potential benefit from administering antibiotic prophylaxis before dental procedures must be weighed against the known risks of lethal toxicity, allergy, and development, selection, and transmission of microbial resistance. The implications of guideline changes and lack of evidence for the full use of antibiotic prophylaxis for the teaching of dentistry have to be further discussed.
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Manso, Sara, José João Mendes, and P. Patrícia Cavaco Silva. "Antibiotic prophylaxis for dental procedures: do dental students know enough?" Annals of Medicine 53, sup1 (April 1, 2021): S33. http://dx.doi.org/10.1080/07853890.2021.1897460.

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GUTSGHIK, ERNÖ, and SÖREN LIPPERT. "Dental procedures and endocarditis prophylaxis: experiences from 108 dental practices." European Journal of Oral Sciences 98, no. 2 (April 1990): 144–48. http://dx.doi.org/10.1111/j.1600-0722.1990.tb00953.x.

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Bahammam, Maha A., and Noha M. Abdelaziz. "Awareness of Antimicrobial Prophylaxis for Infective Endocarditis Among Dental Students and Interns at a Teaching Hospital in Jeddah, Saudi Arabia." Open Dentistry Journal 9, no. 1 (June 22, 2015): 176–80. http://dx.doi.org/10.2174/1874210601509010176.

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Introduction : Infective endocarditis is a serious infection of the heart endothelium and valves. It carries long-term health risks and compromises the heart condition. However, this condition has been rarely observed since the introduction of appropriate antibiotic prophylaxis. Dentists play a major role in preventing infective endocarditis in susceptible patients. In this study, we assessed the levels of awareness about antibiotic prophylaxis for infective endocarditis among students and young dentists at King Abdulaziz University, Jeddah, Saudi Arabia. Methods : This cross-sectional study included 367 dental students and dental interns who answered a questionnaire designed to assess their awareness levels; it included questions pertaining to demographic information and questions examining the general knowledge of the participants with regard to antibiotic prophylaxis for infective endocarditis. Results : An average of 50% of the participants clearly lacked knowledge regarding the conditions that require antibiotic prophylaxis, while an average of 65% provided correct answers pertaining to the conditions that do not require prophylaxis. Regarding dental procedures that require prophylaxis, the majority of responses were correct with an average of 71.2%. With regard to the type of antibiotic to be prescribed, 63.5% of the participants chose to prescribe 2 g of amoxicillin as a first-line antibiotic. Conclusion : The results of this study showed that the levels of awareness about antibiotic prophylaxis for infective endocarditis are below 100%. Awareness is essential because of the cardiac risks associated with the lack of appropriate treatment. Up-to-date and accurate knowledge is mandatory for all dental students and interns who see and treat patients on a daily basis.
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37

LNU, Alexander, and Simy Mathew. "Post-Exposure Prophylaxis: What Every Dental Personnel Should Know." World Journal of Dentistry 2, no. 2 (2011): 169–74. http://dx.doi.org/10.5005/wjoud-2-2-169.

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ABSTRACT Percutaneous injuries in the dental office are one of the main risk factors for the transmission of diseases like hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV). HBV is an important infectious disease that is to be focused on in a dental setting. According to Centers for Disease Control and Prevention (CDC), dental work ranks first in the frequency of potential sources for acquiring viral hepatitis, while dental employment ranks eleventh. It is necessary that all dental practitioners are aware of the post-exposure prophylaxis (PEP) to be followed in case of exposure to HBV, HCV or HIV and the protocol followed in situations of exposure and that adequate reporting of the situation is performed. The protocol discussed is to be displayed in all dental settings so that every dental personnel will be aware of the necessary prophylaxis to be followed in any case of accidental exposure to infected source.
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Miyashita-Kobayashi, Aya, Akiko Haruyama, Keigo Nakamura, Chia-Ying Wu, Akihiro Kuroiwa, Nobuo Yoshinari, and Atsushi Kameyama. "Changes in Gloss Alteration, Surface Roughness, and Color of Direct Dental Restorative Materials after Professional Dental Prophylaxis." Journal of Functional Biomaterials 15, no. 1 (December 23, 2023): 8. http://dx.doi.org/10.3390/jfb15010008.

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In the context of optimizing dental care for patients who are elderly, the purpose of this in vitro study was to evaluate the surface gloss (with a micro-area gloss meter) of, surface roughness (with a compact surface roughness measuring instrument) of, and color change (with a dental colorimeter) in two commercially available injectable resin-based composites (Estelite Universal Flow (EUF) and Beautifil Flow Plus F00 (BFP)) as well as two glass–ionomer cements (GC Fuji II LC CAPSULE (FLC) and GC Fuji IX GP EXTRA CAPSULE (FGP)), before and after dental prophylaxis. After 24 h, the surfaces of each specimen were polished at 2500 rpm with a prophy brush (Mersage Brush, Shofu) and one-step prophylaxis paste (Prophy Paste Pro, Directa): under 100 or 300 gf load, and for 10 or 30 s, 4× cycles of cleaning. After mechanical cleaning, conditions were found for a significant reduction in the gloss level (EUF, BFP, or FLC; p < 0.05) and a significant increase in surface roughness (BFP; 300 gf load, 10 s × four cycles of cleaning). Overall, the longer time or higher prophylaxis load tended to decrease the surface gloss. However, the observed change in surface roughness varied between the restorative materials. There was no color change post-prophylaxis.
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39

Furlan, NF, MBD Gaviäo, TS Barbosa, J. Nicolau, and PM Castelo. "Salivary Cortisol, Alpha-Amylase and Heart Rate Variation in Response to Dental Treatment in Children." Journal of Clinical Pediatric Dentistry 37, no. 1 (September 1, 2012): 83–87. http://dx.doi.org/10.17796/jcpd.37.1.n32m21n08417v363.

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Anxiety and stress are usually related to the dental treatment situation. The objective was to investigate salivary cortisol and alpha-amylase levels (salivary biomarkers) and heart rate in children undergoing a minor dental procedure (dental prophylaxis). Study design. In total, 31 children (range 84-95 months) of both genders without caries or history of dental treatment/pain/trauma were selected. Three saliva samples were gathered: one prior to dental prophylaxis, one immediately after, and one ten minutes later. Weight and height were assessed, and heart rate was evaluated prior to and during the procedure. Data were analyzed by correlation tests and t-test/Wilcoxon (α = 0.05). Results. Higher cortisol and amylase levels were observed before prophylaxis compared to afterward. Cortisol and amylase levels did not show a significant correlation, nor did salivary biomarkers and body mass index. However, heart rate and amylase levels showed a significant positive correlation. Conclusions. In the studied sample, certain anticipation of the dental treatment was observed because higher cortisol and amylase levels were observed before, rather than after, the event; moreover, a significant correlation between amylase levels and heart rate was observed. Thus, salivary biomarkers may be a valuable tool for evaluating anxiety-producing events, such as dental treatment, in children.
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40

Carmona, I. Tomás, P. Diz Dios, and C. Scully. "Efficacy of Antibiotic Prophylactic Regimens for the Prevention of Bacterial Endocarditis of Oral Origin." Journal of Dental Research 86, no. 12 (December 2007): 1142–59. http://dx.doi.org/10.1177/154405910708601203.

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Despite the controversy about the risk of individuals developing bacterial endocarditis of oral origin, numerous Expert Committees in different countries continue to publish prophylactic regimens for the prevention of bacterial endocarditis secondary to dental procedures. In this paper, we analyze the efficacy of antibiotic prophylaxis in the prevention of bacteremia following dental manipulations and in the prevention of bacterial endocarditis (in both animal models and human studies). Antibiotic prophylaxis guidelines remain consensus-based, and there is scientific evidence of the efficacy of amoxicillin in the prevention of bacteremia following dental procedures, although the results reported do not confirm the efficacy of other recommended antibiotics. The majority of studies on experimental models of bacterial endocarditis have verified the efficacy of antibiotics administered after the induction of bacteremia, confirming the efficacy of antibiotic prophylaxis in later stages in the development of bacterial endocarditis. There is no scientific evidence that prophylaxis with penicillin is effective in reducing bacterial endocarditis secondary to dental procedures in patients considered to be "at risk". It has been suggested that there is a high risk of severe allergic reactions secondary to prophylactically administered penicillins, but, in reality, very few cases have been reported in the literature. It has been demonstrated that antibiotic prophylaxis could contribute to the development of bacterial resistance, but only after the administration of several consecutive doses. Future research on bacterial endocarditis prophylactic protocols should involve the re-evaluation of the time and route of administration of antibiotic prophylaxis, and a search for alternative antimicrobials.
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41

Kamps, T. "Antibiotic prophylaxis and (pre-)dental implant surgery." Nederlands Tijdschrift voor Tandheelkunde 126, no. 10 (October 4, 2019): 527–32. http://dx.doi.org/10.5177/ntvt.2019.10.19067.

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42

Taubert, Kathryn A., and Walter Wilson. "Is endocarditis prophylaxis for dental procedures necessary?" Heart Asia 9, no. 1 (February 2017): 63–67. http://dx.doi.org/10.1136/heartasia-2016-010810.

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43

&NA;. "Antibacterial prophylaxis for dental treatment - controversy continues." Inpharma Weekly &NA;, no. 834 (April 1992): 16. http://dx.doi.org/10.2165/00128413-199208340-00033.

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44

Uyemura, Monte Colin. "Antibiotic prophylaxis for medical and dental procedures." Postgraduate Medicine 98, no. 2 (August 1995): 137–54. http://dx.doi.org/10.1080/00325481.1995.11946033.

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45

Llibre, J. M., J. Cucurull, A. Aloy, and J. A. Hernandez. "Antimicrobial prophylaxis for dental extractions after splenectomy." Lancet 337, no. 8755 (June 1991): 1485–86. http://dx.doi.org/10.1016/0140-6736(91)93180-h.

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46

FRERE, CATHRYN L., RICHARD CROUT, JACK YORTY, and DANIEL W. McNEIL. "Effects of Audiovisual Distraction During Dental Prophylaxis." Journal of the American Dental Association 132, no. 7 (July 2001): 1031–38. http://dx.doi.org/10.14219/jada.archive.2001.0309.

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47

Heidmann, J., and H. Birn. "The Self-Fulfilling Prophecy in Dental Prophylaxis." Scandinavian Journal of Social Medicine 15, no. 1 (March 1987): 49–53. http://dx.doi.org/10.1177/140349488701500108.

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This report deals with the influence of the self-fulfilling prophecy on dental prophylaxis. The aim was to test if this phenomenon had any influence on the treatment of patients, they and their therapeutist's perception of each other and the result of the prophylactic work. Sixty patients and 34 students were involved. The patients were randomly classified as “good” or “bad”. Twenty-seven students had a patient from each group. Dental plaque and gingival inflammation were recorded before and after the treatment. No difference in improvement between the two groups could be shown. Both patients and students were interviewed about their experiences and feelings during the treatment. All patients were satisfied with their therapeutist. The students generally accepted the classification although they were made aware of the self-fulfilling prophecy. This was confirmed by a significantly higher frequency of patient drop-outs, broken appointments and critical notes about the patients in the “bad” group compared to the “good”. The conclusions are that the self-fulfilling prophecy can be initiated by even minor notes in patient files, and that this affects the treatment of patients.
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48

Grant, A., and C. Hoddinott. "Joint replacement, dental surgery, and antibiotic prophylaxis." BMJ 304, no. 6832 (April 11, 1992): 959. http://dx.doi.org/10.1136/bmj.304.6832.959.

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49

Shaw, Frederic E. "Hepatitis B Prophylaxis in Dental Professionals-Reply." JAMA: The Journal of the American Medical Association 256, no. 23 (December 19, 1986): 3217. http://dx.doi.org/10.1001/jama.1986.03380230041018.

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50

Chang, C. T., S. P. Liu, C. H. Muo, C. H. Tsai, and Y. F. Huang. "Dental Prophylaxis and Osteoradionecrosis: A Population-Based Study." Journal of Dental Research 96, no. 5 (January 17, 2017): 531–38. http://dx.doi.org/10.1177/0022034516687282.

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The aim of this study was to investigate the association of different dental prophylactic modalities and osteoradionecrosis (ORN) and determine the risk of ORN under different timing periods of scaling, with the use chlorhexidine mouth rinse after surgery and with different strategies of fluoride gel application in head and neck cancer (HNC) participants. A cohort of 18,231 HNC participants, including 941 ORN patients and 17,290 matched control cases, were enrolled from a Longitudinal Health Insurance Database for Catastrophic Illness Patients (LHID-CIP) in Taiwan. Based on different dental prophylactic modalities before radiotherapy, including chlorhexidine mouth rinse, scaling, and fluoride gel, all HNC subjects were stratified into different groups. The Cox proportional hazard regression was used to compare ORN incidences under different dental prophylactic modalities. The results revealed that scaling and chlorhexidine mouth rinse were significantly related to ORN risk ( P = 0.004 and P < 0.0001). Chlorhexidine mouth rinse was highly correlated to ORN occurrence (hazard ratio [HR], 1.83–2.66), as exposure increased the risk by 2.43-fold among oral cancer patients, regardless of whether they had received major oral surgery or not. Oral cancer patients receiving scaling within 2 wk before radiotherapy increased their incidence of ORN by 1.28-fold compared with patients who had not undergone scaling within 6 mo. There is no significance of fluoride application for dental prophylaxis in increasing ORN occurrence. In conclusion, dental prophylaxis before radiotherapy is strongly correlated to ORN in HNC patients. Chlorhexidine exposure and dental scaling within 2 wk before radiotherapy is significantly related to ORN risk, especially in oral cancer patients. The use of 1.1% NaF topical application did not significantly increase the risk of ORN in HNC patients. An optimal dental prophylaxis protocol to reduce ORN should concern cancer location, cautious prescription of chlorhexidine mouth rinse, and proper timing of scaling.
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