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Al-Omishi, Makarim. "Rampant dental caries." Thesis, Faculty of Dentistry, 1990. http://hdl.handle.net/2123/4260.
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Vitorino, Rui Miguel Pinheiro. "Dental caries: a proteomic approach." Doctoral thesis, Universidade de Aveiro, 2004. http://hdl.handle.net/10773/17671.
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Doutoramento em BioQuímicaA cárie dentária é uma doença complexa que afecta uma grande parte da população mundial independentemente do sexo, idade ou etnia. Este processo é dependente de factores biológicos que se encontram presentes na saliva e placa dentária. Em seguimento do referido, amostras de saliva foram colectadas de indivíduos caracterizados em função dos índices DMFT e DMFS. A avaliação dos convencionais parâmetros clínicos como por exemplo fluxo salivar, capacidade tampão, pH usados na avaliação do risco para a cárie dentária em combinação com dieta, hábitos de higiene e tabagismo foram realizados para todos os indivíduos participantes do qual se observou a ausência de uma positiva correlação com o índice DMFT. Uma vez que os factores biológicos presentes na saliva influenciam o processo da cárie dentária, o objectivo deste trabalho consistiu na investigação de uma possível correlação entre as proteínas e peptídeos da saliva e o processo da cárie dentária. A caracterização das proteínas e peptídeos da saliva foi alcançada utilizando electroforese bidimensional (2-DE), cromatografia líquida de alta resolução (HPLC) combinada com a espectrometria de massa (MS), do qual resultou a identificação de 38 proteínas das quais 12 foram identificadas pela primeira vez por 2-DE e 22 peptídeos por HPLC-MS também identificados pela primeira vez. Ensaios realizados para o estudo da composição da película dentária seguiram a mesma metodologia descrita para a caracterização das proteínas e peptídeos da saliva sendo realizados inicialmente in vitro e confi rmados posteriormente por ensaios in vivo. A adsorção dos componentes salivares à hidroxiapatite é um processo selectivo com predominância de componentes salivares de baixo peso molecular. Contudo, amilase, lactoferrina, IgA salivar e anidrase carbónica VI foram também identificadas. A extracção sequencial usando guanidina e ácido trifluoroacético das proteínas/peptídeos adsorvidas à hidroxiapatite permitiu uma avaliação da força das ligações estabelecidas. Destes ensaios verificou-se que proteínas ricas em prolina (PRP-1/3), cistatina S, statherina e histatina 1 estabeleciam interacções fortes com a hidroxiapatite permanecendo adsorvidas após extracção com guanidina. As proteínas caracterizadas da saliva e da película dentária foram correlacionadas com o índice DMFT apresentando uma predominância de elevadas quantidades de cistatinas, PRP -1/3, statherina e histatina 1 no grupo de indivíduos sem cárie. O reduzido número de fragmentos em associação com as elevadas quantidades de cistatinas podem sugerir um controle mais eficiente da actividade proteólitica evitando desta maneira a degradação de importantes proteínas salivares no grupo de indivíduos sem cárie. A composição da película dentária é afectada pela composição proteica da saliva encontrando-se as referidas proteínas em maior quantidade. Os dados obtidos sugerem uma eficiente protecção por parte das proteínas da saliva contra a cárie dentária em particular a PRP-1/3, statherina e histatina 1, provavelmente devido à sua participação nos processos de remineralização na superfície do dente, e das cistatinas na diminuição da actividade proteólitica.
Dental caries is a complex disease process that affects a large proportion of the world population, regardless of gender, age and ethnicity. This process is dependent upon biological factors that are present within saliva and dental plaque. Following this, whole saliva was collected from selected individuals characterised according its DMFT and DMFS scores. Evaluation of the conventional clinical parameters such as flow rate, buffering capacity, pH used for caries risk assessment in combination with diet, hygiene and smoke habits was performed for all participating subjects showing absence of a statistic positive correlation with DMFT index. Since biological factors present on saliva influence dental caries process, the aim of this study was to investigate how salivary proteins and peptides are correlated with this pathology. Characterisation of salivary proteins and peptides was achieved using twodimensional gel electrophoresis (2-DE) and high performance liquid chromatography (HPLC) in combination with mass spectrometry (MS) resulting in the identification of 38 proteins, being 12 proteins identified by 2-DE and 22 peptides by HPLC-MS were identified for the first time. Experiments to study enamel pellicle composition were performed following the same methodology described for salivary proteins and peptides, initially in vitro being supported with in vivo assays. Adsorption of salivary components to hydroxyapatite showed to be a selective process with a predominance of low molecular weight salivary components. However, amylase, lactoferrin, S-IgA, carbonic anhydrase VI were also identified. A sequential extraction, using of guanidine and trifluoroacetic acid, of the adsorbed proteins/peptides to hydroxyapatite allowed to evaluate the strength of the establish interactions. From this experiments, proline-rich proteins (PRP -1/3), cystatin S, statherin, histatin 1 exhibited a strong interaction with hydroxyapatite remaining adsorbed after guanidine extraction. Characterised salivary proteins from whole saliva and enamel pellicle were correlated with DMFT index showing a predominance of higher amounts of cystatins, PRP-1/3, statherin and histatin 1 in caries free group. Decreased number of fragments in association with higher amounts of cystatins may suggest a more effective control in proteolytic activity which avoid the degradation of important salivary proteins from caries free group. Acquired pellicle composition is affected by whole saliva protein composition being the above referred proteins present in higher amounts. Obtained data suggest an effective protective role of several salivary proteins to dental caries in particular of PRP-1/3, statherin and histatin 1, possibly due to their participation on remineralization processes at the tooth surface, and of cystatins probably by decreasing proteolytic activity.
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Subrahmanyan, Usha. "Fluorides And Root Surface Dental Caries." Thesis, Faculty of Dentistry, 1988. http://hdl.handle.net/2123/5028.
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Hamama, Hamdi Hosni Hamdan Eldesouki. "Influence of chemomechanical caries removal methods on dentine." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/202369.
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Chemomechanical caries excavation is an excellent example of conservative caries removal methods due to its ability to reliably preserve a greater thickness of caries-affected dentine (CAD). Chemomechanical caries removal (CMCR) agents dissolve the denatured collagen fibrils leaving the sound and partially degraded fibrils intact. Also, one of the main advantages of the CMCR method is its characteristic visual excavation end point sign, after this point, the solution fails to become turbid. Chemomechanical caries removal agents are classified based on their chemistry into sodium hypochlorite (NaOCl)- or enzyme-based CMCR agents.
The aim of this project was to evaluate the efficacy of currently available chemomechanical caries removal methods and their effects on tooth substrate, residual bacteria, and bonding to dentine with either resin- or resin-modified glass ionomer (RM-GIC)-based adhesives. The current project was designed to answer five research questions. The first research question aimed to compare the caries excavation time between CMCR and rotary caries removal methods. According to the outcome of this study, the NaOCl-based CMCR method is more time consuming compared with the enzyme-based CMCR method. Furthermore, no significant difference in caries excavation time was found between the enzymebased CMCR and the caries-detector guided rotary caries excavation method.
The second research question investigated the effects of CMCR methods on surface topography, hardness and chemical structure of dentine. The morphological analysis showed that there was no smear layer formed following enzyme-based CMCR; while it was partially absent after the NaOCl-based CMCR method. Also, the Vickers hardness of residual dentine following both CMCR methods was lower than the hardness of dentine following the rotary caries removal method. Moreover, the outcome of this study also revealed that the CMCR methods investigated had no adverse effect on the chemical structure of dentine.
The third research question was regarding the evaluation of the antibacterial effects of CMCR agents. Accordingly, a study was conducted on coronal cariesfree dentine discs using a modified non-invasive protocol. This confocal laser scanning microscopy study reported that the enzyme-based CMCR agent (Papacarie) showed an antimicrobial effect similar to 2% chlorhexidine gluconate solution (gold standard antibacterial solution). The NaOCl-based CMCR agent (Carisolv) showed a weak antibacterial activity, which could be improved by subsequent application of a silver diamine fluoride and potassium iodide agent.
The ‘adhesion studies section’ of this project consists of three studies and was conducted to answer the fourth and fifth research questions of this project. The outcomes of the first and second studies showed that surface treatment of dentine with 37% phosphoric acid for 5 seconds had no adverse effect on bonding of RMGIC adhesives to both sound and caries-affected dentine, which addressed the fourth research question.
The purpose of the last research question was to evaluate the effect of CMCR method on bonding of MDP-containing self-etch and RM-GIC adhesives to residual caries-affected dentine. It was concluded that CMCR methods had no adverse effects on bonding to dentine and both adhesive systems showed good bond strengths to caries-affected dentine.published_or_final_version
Dentistry
Doctoral
Doctor of Philosophy
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Alm, Anita. "On dental caries and caries-related factors in children and teenagers /." Göteborg : Dept. of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, 2008. http://hdl.handle.net/2077/10146.
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Falcón, G., I. Ferreyra, S. Gómez, A. Munive, D. Porras, and E. Terán. "Caries y gingivitis." Universidad Peruana de Ciencias Aplicadas - UPC, 2009. http://hdl.handle.net/10757/272490.
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Pakdaman, Afsaneh. "Dental Student Management Of Non-Invasive Intervention For Dental Caries." Thesis, The University of Sydney, 2006. http://hdl.handle.net/2123/4961.
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Gale, Martin Stuart. "Dental filled resin restorations seal integrity of the dentine bond /." Thesis, Click to view the E-thesis via HKUTO, 1996. http://sunzi.lib.hku.hk/hkuto/record/B36544358.
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Macklam, Iain Douglas. "Microelectrochemical investigations of early stage dental caries." Thesis, University of Warwick, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412887.
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Chankanka, Oitip. "Dietary intake and dental caries in children." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/653.
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Dental caries is a common childhood disease and important health problem in the United States and throughout the world. Most studies that have assessed risk factors for dental caries focused on non-modifiable risk factors such as previous caries experience and socioeconomic status. It is also important to investigate modifiable risk factors that can be used in developing guidelines for risk assessment and prevention. The present dissertation assessed mainly the associations between dental caries and modifiable factors, including dietary factors, water fluoride levels and toothbrushing frequency in children, while adjusting for non-modifiable factors. Data were obtained from subjects who were participants in the Iowa Fluoride Study. Dietary data were collected using 3-day dietary diaries from 1.5 months to 8.5 years and detailed questionnaires from 9 years to 13 years. Dental caries examinations were conducted at about 5, 9 and 13 years of age. There are three main analyses.
The first analysis assessed risk factors for a 4 group primary dentition caries experience variable: the caries-free (reference group), the d1, the d2+f, and the d1d2+f groups. The dietary consumption frequencies (from ages 3 to 5 years) for the children in the 4 caries groups were compared using multivariable multinomial regression analyses. Lower consumption frequency of milk at meals and greater consumption frequency of pre-sweetened cereal at meals significantly increased the likelihood of being in the d1 group. Greater consumption frequency of regular soda pop at snacks significantly increased the likelihood of being in the d1d2+f group. Greater consumption frequency of added sugars at snacks significantly increased chance to be in the d2+f group and the d1d2+f group.
The second manuscript assessed risk factors for new mixed dentition cavitated caries determined based on surface-specific transitions from the primary to mixed dentition exams on 16 teeth using logistic regression analysis. Greater consumption frequency of processed starch at snacks significantly increased the likelihood of having new cavitated caries (p = 0.04 for the model excluding previous caries experience).
The third manuscript used negative binomial regression with the Generalized Linear Mixed Models procedure to assess separately the longitudinal associations of 1) new non-cavitated caries and 2) new cavitated caries with modifiable risk factors. Surface-specific counts of new non-cavitated caries and cavitated caries at each of the primary, mixed and permanent dentition examinations were used as outcome variables. Greater consumption frequency of 100% juice was significantly associated with fewer non-cavitated and fewer cavitated caries surfaces.
In this study, some factors were associated with caries at one age only, while others were associated with caries across childhood. Consumption of foods or beverages at meals generally decreased their cariogenicity. Previous caries experience is strongly associated with other independent variables in the regression models that examined risk factors for new cavitated caries. Thus modifiable factors that usually have weaker associations with caries might not be retained in the models due to collinearity issues. Future researchers are encouraged to present results both ways so that scientific communities can best interpret the complex results. Also, repeated measures analysis might be more appropriate for variables that are common in all age groups, such as toothbrushing frequency and fluoride exposures. More studies of the complex relationships between diet and caries are needed, including additional studies that place more emphasis on investigation of modifiable risk factors for both non-cavitated and cavitated caries.
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Haj-Ali, Reem Spencer Paulette. "Adhesive diffusion into caries-affected dentin under simulated oral conditions." Diss., UMK access, 2004.
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Thesis (M.S.)--School of Dentistry. University of Missouri--Kansas City, 2004."A thesis in oral biology." Advisor: Paulette Spencer. Typescript. Vita. Title from "catalog record" of the print edition Description based on contents viewed Feb. 24, 2006. Includes bibliographical references (leaves 58-65). Online version of the print edition.
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Keltjens, Herman Michiel Antonius Marie. "Microbiology and preventive treatment of root surface caries Microbiologie en preventieve behandeling van tandwortelcariës /." Helden-Panningen : De Gouden Leeuv Drukkerij B.V, 1988. http://catalog.hathitrust.org/api/volumes/oclc/19650028.html.
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Thesis (doctoral)--Katholieke Universiteit te Nijmegen, 1988.Text in English with a summary in Dutch. "Een wetenschappelijke proeve op het gebied van geneeskunde en tandheelkunde." Includes bibliographical references.
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Salerno, Antonella. "Manejo de caries profunda." Trabajo final de especialización, Universidad Nacional de Cuyo. Facultad de Odontología, 2020. http://bdigital.uncu.edu.ar/15365.
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Si no se trata, la caries avanzará a través de la dentina y, finalmente, la infección llegará a la pulpa y como consecuencia, la pieza dentaria sufrirá pulpitis y hasta, una posible necrosis; sin embargo, si la lesión se gestiona de manera conservadora, la recuperación pulpar se produce incluso en lesiones cariosas profundas. Una parte importante, y esencial, del proceso de diagnóstico de la enfermedad de pulpa es el uso de pruebas de sensibilidad pulpar. Sin embargo, una deficiencia importante con estas pruebas es que sólo indirectamente proporcionan una indicación del estado de la pulpa midiendo una respuesta neuronal en lugar del suministro vascular, por lo que pueden ocurrir resultados falsos positivos y falsos negativos.
El desarrollo de nuevos materiales de protección pulpar como el agregado de trióxido mineral (MTA) o Biodentine™, ha dado lugar a tratamientos más predecibles tanto desde una perspectiva histológica como clínica.
El objetivo de este trabajo es realizar una revisión bibliográfica de las herramientas de diagnóstico, estrategias de tratamiento de caries profundas, y tratamiento de protección pulpar directa con biocerámicos.
En el presente trabajo se describe un caso clínico en el cual se realizó un tratamiento de pulpa vital en elemento 47, utilizando como material de obturación MTA REPAIR HP Angelus® (Brasil), obteniendo como resultado pulpa vital según signos y síntomas tanto clínicos como radiográficos, a los 6 meses de haber realizado dicho tratamiento.
El mantenimiento de la vitalidad pulpar y la promoción de estrategias con base biológica son el núcleo en el manejo de la caries profunda, desde una perspectiva científica, por una mayor comprensión de los procesos inflamatorios, de reparación e interacción de la pulpa dental con el material.Fil: Salerno, Antonella. Universidad Nacional de Cuyo. Facultad de Odontología.
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Aaltonen, Antti S. "Natural immunity in dental caries longitudinal studies of serum and salivary antibodies reactive with Streptococcus mutans in young children in relation to dental caries and some maternal factors /." Turku, Finland : University of Turku, Institute of Dentistry, 1989. http://catalog.hathitrust.org/api/volumes/oclc/20115011.html.
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Pienihäkkinen, Kaisu. "Screening for high caries increment in children." Turku : Kirjapaino Grafia Oy, 1987. http://books.google.com/books?id=8hxqAAAAMAAJ.
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Thesis--University of Turku, 1987."Also published in: Proceedings of the Finnish Dental Society, 1988, Vol. 84, Suppl. II"--T.p. verso. At head of title: From the Department of Cariology, Institute of Dentistry, University of Turku, Turku, Finland, and the Department of Conservative Dentistry, Semmelweis Medical University, Budapest, Hungary. Includes bibliographical references (p. 62-72).
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Peck, S. "Acoustic microscopy of caries in human dental enamel." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375312.
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Klinke, Thomas, Bernhard Guggenheim, Wolfgang Klimm, and Thomas Thurnheer. "Dental Caries in Rats Associated with Candida albicans." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-133205.
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In addition to occasional opportunistic colonization of the oral mucosa, Candida albicans is frequently found in carious dentin. The yeast’s potential to induce dental caries as a consequence of its pronounced ability to produce and tolerate acids was investigated. Eighty caries-active Osborne-Mendel rats were raised on an ampicillin-supplemented diet and exposed to C. albicans and/or Streptococcus mutans, except for controls. Throughout the 28-day test period, the animals were offered the modified cariogenic diet 2000a, containing 40% various sugars. Subsequently, maxillary molars were scored for plaque extent. After dissection, the mandibular molars were evaluated for smooth surface and fissure caries. Test animals exposed to C. albicans displayed considerably more advanced fissure lesions (p < 0.001) than non-exposed controls. While S. mutans yielded similar results, a combined association of C. albicans and S. mutans had no effect on occlusal caries incidence. Substituting dietary sucrose by glucose did not modify caries induction by C. albicans. However, animals fed a diet containing 20% of both sugars showed no differences to non-infected controls. Smooth surface caries was not generated by the yeast. This study provides experimental evidence that C. albicans is capable of causing occlusal caries in rats at a high rateDieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich
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Klinke, Thomas, Bernhard Guggenheim, Wolfgang Klimm, and Thomas Thurnheer. "Dental Caries in Rats Associated with Candida albicans." Karger, 2011. https://tud.qucosa.de/id/qucosa%3A27495.
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In addition to occasional opportunistic colonization of the oral mucosa, Candida albicans is frequently found in carious dentin. The yeast’s potential to induce dental caries as a consequence of its pronounced ability to produce and tolerate acids was investigated. Eighty caries-active Osborne-Mendel rats were raised on an ampicillin-supplemented diet and exposed to C. albicans and/or Streptococcus mutans, except for controls. Throughout the 28-day test period, the animals were offered the modified cariogenic diet 2000a, containing 40% various sugars. Subsequently, maxillary molars were scored for plaque extent. After dissection, the mandibular molars were evaluated for smooth surface and fissure caries. Test animals exposed to C. albicans displayed considerably more advanced fissure lesions (p < 0.001) than non-exposed controls. While S. mutans yielded similar results, a combined association of C. albicans and S. mutans had no effect on occlusal caries incidence. Substituting dietary sucrose by glucose did not modify caries induction by C. albicans. However, animals fed a diet containing 20% of both sugars showed no differences to non-infected controls. Smooth surface caries was not generated by the yeast. This study provides experimental evidence that C. albicans is capable of causing occlusal caries in rats at a high rate.Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
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Owens, Gareth. "In vitro caries : dental plaque formation and acidogenicity." Thesis, University of Liverpool, 2013. http://livrepository.liverpool.ac.uk/15495/.
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Dental caries is a significant disease world-wide and although a massive reduction in prevalence has occurred over the past 50 years, incidents of this disease persist (particularly on the occlusal or aproximal surfaces and concerning younger demographics). The main reason for the observed reduction is exposure to fluoride either though water fluoridation and delivery by dentifrice. Environmental exposure reduces incidence by incorporation into the mineral phase of the hard tissue and, as a result, increases the resistance of the enamel mineral to acid-induced demineralisation. Several mechanisms have been proposed in an attempt to explain the caries-inhibiting effects of fluoride however its influence on the balance between de- and re-mineralisation episodes appears to be the principal route by which fluorides exert their effects. Efforts geared towards the continual improvement of fluoride delivery systems have also been successful to some extent and thus further exploration shows promise of improving the anticaries efficacy further. However, a complication is met in that, in vivo, multiple factors interrelated and consequently, differences in the consortia within natural oral biofilms combined with unavoidable inter-individual variations confound clinical investigations and make the distinction between relevant aspects of the process difficult. One possible alternative strategy is the development of in vitro biological models to simulate this process to a point of reflecting the in vivo situation whilst retaining control over the parameters which are known to be crucial to the progression of the disease. To this end, the Constant-Depth Film Fermenter (CDFF) has emerged as powerful tool to potentially meet the needs of current in vitro research. However, due to the lack of an inter-disciplinary approach to multi-faceted disease process, the full potential of the CDFF has not yet been reached. Therefore, the CDFF model was applied to study of anti-caries strategies which aimed to increase the persistence of the fluorides within natural microcosm biofilms. Enamel lesions were successfully produced within this system and, using a combination of both biological and non-biological demineralisations systems, the effects of anticaries agents (calcium and fluoride) were also investigated for their effects on lesion progression or reversal. Sodium fluoride (NaF; 300 ppm F-) exposures exhibited an ambiguous response on the microbial community although definite anticaries activity. Conversely, calcium lactate pre-rinses (Ca-lactate; 100 mM) appears to possess some inhibitory activity on the biofilms produced within the model whereas a less effective anticaries activity was observed in comparison to NaF exposures alone. Thus, further investigation of the effects of Ca-lactate should be pursued. Operation of the CDFF was also further developed to meet the needs of this study and analyses were performed on an integrative basis in order to capture the physiochemical events which take place during caries lesion formation. Microcosm plaques were shown to be highly diverse with respect to their community although homology was found on the bias of their ultimate definition, cariogenicity. The synthesis of inorganic mineral reservoirs within microcosm biofilms holds great potential for augmenting the physiology of the plaque and for increasing the efficacy of fluorides for prevention of enamel demineralisation. Microcosm biofilms may also have an adaptive capacity which could result in predicable response patterns. Ultimately, a holistic approach to the study of caries within a biological context provides greater insight into the caries process than approaches which lack specific interactions for the purposes of assigning direct relationships. With the successful development of a fully functional enamel caries model, the possibilities are endless.
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Burnside, Girvan. "Multilevel modelling of dental caries clinical trail data." Thesis, University of Liverpool, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526853.
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Wang, Raymond Ruey-Rong. "Diet To Increase Tooth Resistance To Dental Caries." Thesis, Faculty of Dentistry, 1989. http://hdl.handle.net/2123/4600.
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Paisi, Martha. "Obesity and dental caries in children in Plymouth." Thesis, University of Plymouth, 2017. http://hdl.handle.net/10026.1/9582.
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Background: Obesity and dental caries are two of the most common conditions affecting children and both have significant implications on children’s wellbeing and future health. Even though research into the relationship between the two conditions has been conducted for many years, results to date remain equivocal. Furthermore, the majority of the studies only examined individual-level determinants of the two conditions. Aim: The current work aimed to examine the nature, direction and effect size of the relationship between obesity and caries in children in Plymouth, United Kingdom. It also aimed to better understand the individual and the broader environmental determinants of the two conditions. Methods: The study was divided into three parts: a systematic review examining the relationship between the two conditions in children and adolescents using a validated and study design specific tool; an analysis of extant data concerning Plymouth children’s weight status and dental caries using a spatial approach; and lastly a school survey of local children aged four to six years, where different types of obesity were examined in relation to dental caries. In the latter survey, several neighbourhood-level and individual characteristics were also examined in relation to the two conditions. Results: The systematic review indicated that there was no consistent association between high Body Mass Index and caries in individuals less than 18 years old. The ecological study identified spatial clusters of obesity and caries in Plymouth children and the results supported the importance of developing geographically focused prevention and intervention strategies which take into account the presence of spatial heterogeneity. The school survey did not find evidence of a relationship between any type of obesity and caries in Plymouth children but identified several indicators that affect the distribution of the two conditions. Conclusions: This work has given insight into the nature, direction and size of the relationship between obesity and caries in Plymouth children and has highlighted several indicators which need to be considered when developing local public health interventions.
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Thearmontree, Angkana. "Twenty year trends of dental caries in US children ages 2-15 years comparing the traditional DMF and adjusted DF indices." Ann Arbor, Mich. : University of Michigan, 1999. http://books.google.com/books?id=IxMvAAAAMAAJ.
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Attathom, Tipapat Armstrong Steven R. "Effect of ethanol-wet bonding to caries affected dentin." Iowa City : University of Iowa, 2009. http://ir.uiowa.edu/etd/278.
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Borkent, Dewi. "Epidemiological, pathological and microbiological study of equine dental caries." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33087.
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Dental caries is caused by acidogenic oral micro-organisms which convert fermentable carbohydrates to acids that damage the tooth by causing a demineralisation and disintegration of the inorganic and organic substances of the tooth, respectively (Soames and Southam, 2005). In horses, two variants of dental caries occur: equine dental peripheral caries (PC) involving the periphery of teeth; and infundibular caries (IC) of the maxillary cheek teeth. Twenty-five veterinarians and equine dental technicians experienced in equine dentistry were recruited to perform a UK-wide survey and examined 706 horses for the presence PC and IC, as well as for concurrent dental disorders. The recorded survey results for individual horses included data on potential risk factors including breed, sex, age, diet and the postcode of stables. The prevalence of PC and IC in this population, was 51.7% and 45.5%, respectively. The most commonly and severely PC affected teeth were the three caudal cheek teeth (Triadan 09-11) and for IC were the Triadan 09s. In a multivariable model without observer as a random effect, potential risk factors for the development of PC were: the presence of IC, the presence of diastema/periodontal disease (PD), the presence of multiple concurrent dental disorders other than IC, being fed 2.1-3.0 kg concentrates per day, and living in South East England and South West England. The risk factors which remained significantly associated with the presence of PC in a multivariable model with observer as a random effect, were: feeding 2.1-3 kg concentrates per day, multiple concurrent dental disorders other than IC, the presence of diastema/periodontal disease; additionally, dental fractures now became significantly associated with the presence of PC. In a multivariable model without observer as a random effect, potential risk factors for the development of IC were: the presence of PC, the presence of multiple dental disorders other than IC, and increasing age. Horses in North England and South West England were significantly less likely to have IC than horses in other regions of England and Scotland. In a multivariable model with observer as random effect, the only remaining risk factors were increasing age and geographical region, with a significantly lower likelihood for horses to have IC in South West England than in the other regions. A molecular microbiological study on equine dental caries using a linear discriminant analysis effect size (LEfSe) at genus or higher level, showed Gemella and Actinobacillus to be the genera most associated with the PC study control group (no PC), and Streptococcus, Olsenella and Scardovia to be the genera most associated with PC. Additionally if LEfSe was performed at genus level only, then an additional genus shown to be associated with PC was Mitsuokella. The genus most associated with IC using LEfSe at genus or higher level was Acidaminococcus, while Bacillus was the genus most associated with the IC study control group (no IC). A pathological study examined PC-affected cheek teeth grossly, histologically and, by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Dental plaque, containing bacteria was found to cover the PC lesions. In peripheral cementum, PC lesions were categorised by their shape on histological cross sections of affected teeth into: flake-type, flask-like, or ellipsoid-shaped lesions or combinations of these patterns. Bacteria from surface lesions penetrated between Sharpey's fibers of cementum in a direction perpendicular to the peripheral aspect of the tooth, destroying the intrinsic fibres and Sharpey's fibers. Bacteria also penetrated in a direction parallel to the peripheral aspect of the tooth, undermining the intrinsic fibres, including at the level of incremental growth lines. Bacteria were also found in ellipsoid-shaped lesions and in cemental lacunae of affected cementum. In dentine affected by PC, bacteria were found within and between damaged dentinal tubules, sometimes causing flake-type lesions similar to those seen in cementum. Bacteria penetrated primary dentine and/or (regular/irregular) secondary dentine from the occlusal surface, or entered primary dentine through cementum and enamel from the peripheral aspect. Dental plaque containing bacteria were sometimes observed in dentinal fissure fractures. PC of enamel was only visible using SEM, because this was the only method which did not require prior decalcification, that almost completely removed enamel. In conclusion, PC and IC are prevalent dental disorders in the examined British equine population. The association between PC and concurrent dental disorders (multiple concurrent dental disorders, diastemata/periodontal disease and dental fractures), indicates that these should be addressed in affected horses. In horses affected by IC, the focus should be on treatment of IC itself (like infundibular fillings), because associations of IC were found with risk factors which cannot (or not easily) be controlled such as age and region. Several bacteria could be identified which were associated with PC and other bacteria were more associated with IC or control groups. It was confirmed in the pathological study that bacteria penetrate the cheek teeth affected by PC and IC. So the focus of treatment of PC and IC can also be on reducing the bacteria associated with PC and IC respectively, or the focus could be on prevention by making the teeth more resistant against caries by fluoride treatment. A critical assessment of the use of chlorhexidine mouthwashes and supplementation of fluoride are needed to evaluate its potential effects on PC and IC.
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Chan, Chi-lap Samuel. "Caries prevalence and feeding habits of toddlers in Hong Kong." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/HKUTO/record/B38628375.
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Gale, Martin Stuart Gale Martin Stuart. "Dental filled resin restorations : seal integrity of the dentine bond /." [Hong Kong] : Faculty of Dentistry, The University of Hong Kong, 1996. http://sunzi.lib.hku.hk/HKUTO/record/B38627942.
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Thesis (Ph.D)--University of Hong Kong, 1997.A journal entitled Three-dimensional reconstruction of microleakage pattern using a sequential grinding technique by M.S. Gale, B.W. Darvell and G.S.P. Cheung bound at back of the thesis. Includes bibliographical references (leaves 495-520) Also available in print.
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Tranæus, Sofia. "Clinical application of QLF and DIAGNOdent : two new methods for quantification of dental caries /." Stockholm : Karolinska Univ. Press, 2002. http://diss.kib.ki.se/2002/91-7349-149-7.
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Hitimana, Hilina. "The association between functional foods and dental caries experience /." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116100.
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Objective: To investigate the association between functional foods and dental caries experience in Quebec children. Methodology: A cross-sectional analysis of the baseline wave of the QUALITY cohort was conducted and included a total of 195 children aged 8-10 years. Dietary information was collected by the use of 24--hour recalls. The adequate and inadequate intakes of specific nutrients were assessed in order to create a functional foods index. Dental caries experience was measured by DMF-S index and further categorized into presence and absence of caries. Data were collected on socio-demographic, oral health behaviour and anthropometric measures (height and weight). Data analysis involved logistic regression. Results: Girls eating functional foods were 89% less likely to have 1 decayed or filled tooth. [OR= 0.11 95% CI= (0.01-0.92)]. Conclusion: Functional foods had a protective effect against dental caries, specifically among girls in this sample of children.
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Lecomber, Andrew Roddie. "Optimisation of dental intraoral radiography for early caries detection." Thesis, University of Newcastle Upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247963.
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López, Mendienta Jesús Ricardo. "Terapia de reemplazo para la Prevención de Caries Dental." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2017. http://hdl.handle.net/20.500.11799/67681.
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La presente tesis tiene como objetivo documentar el uso de la terapia de reemplazo en la prevención de caries dental.En general, la terapia de reemplazo emplea una cepa efectora cuidadosamente construida que proporciona una serie de ventajas sobre las estrategias convencionales de prevención y las vacunas orales. Para la prevención de la caries dental, un único régimen de colonización que conduzca a la colonización persistente de una cepa efectora debe proporcionar protección a lo largo de toda la vida. En el caso de que la cepa efectora no persista indefinidamente en algunos sujetos, la reaplicación puede hacerse cuando surge la necesidad sin ninguna preocupación adicional significativa. Una de las mayores ventajas de la terapia de reemplazo es que no hay cuidados adicionales en prevención de caries dental y enfermedad periodontal por parte del paciente, aunque las medidas de higiene bucal para prevenir las enfermedades periodontales seguirán siendo necesarias. Si finalmente es exitoso, el uso de la ingeniería genética para adaptar una cepa efectora para la terapia de reemplazo para la caries dental, se estimularán los esfuerzos para prevenir otras enfermedades infecciosas también.
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Van, Wyk Candice. "Trends in dental caries prevalence and severity in South Africa." Pretoria : [s.n.], 2007. http://upetd.up.ac.za/thesis/available/etd-08222008-172346/.
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Evens, Carina Capps. "Snacking patterns as a risk factor for early childhood caries /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/10902.
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Macek, Mark D. "The relationship of socioeconomic status to the prevalence of dental caries and fluorosis in the elementary schoolchildren of Genesee County, Michigan." Ann Arbor, Mich. : University of Michigan, 1998. http://books.google.com/books?id=lBQvAAAAMAAJ.
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Schulz-Katterbach, Michèle Sabrina. "Cannabis and caries - does regular cannabis use increase the risk of caries in cigarette smokers? /." [S.l.] : [s.n.], 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000297946.
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Ellicker, Mosic Tamara. "Prevalencia de caries en niños de 8 años que residen desde su nacimiento en zonas no fluoradas y asisten a escuelas con y sin programa de alimentación escolar fluorado (PAE-F) /." Tesis, Universidad de Chile, 2010. http://repositorio.uchile.cl/handle/2250/133793.
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Trabajo de Investigación Requisito para optar al Título de Cirujano DentistaExisten estudios que han demostrado la efectividad de la leche como vehículo alternativo de F - para la prevención de caries en lugares donde no es posible la fluoruración del agua potable. En Chile, la distribución de leche con F se realiza a través del Programa de Alimentación Escolar fluorurado (PAE-F). El objetivo del presente estudio ha sido comparar la prevalencia y severidad de caries dental en niños y niñas de 8 años de edad, que residen desde su nacimiento en zonas no fluoruradas y que asisten a escuelas municipales de las comunas Pirque y Maipú, con y sin PAE-F, respectivamente. Se seleccionó una muestra por conveniencia constituida por 90 niños y niñas de 8 años de edad, 40 pertenecientes a Pirque y 50 a Maipú. Para establecer el porcentaje de niños libres de caries se utilizó la metodología descrita por la OMS y para determinar la severidad se utilizaron los índices ceo-d y COP-D. En el análisis estadístico se emplearon los test Chi-cuadrado y MannWhitney, considerándose un nivel de significancia del 0,05. El estudio reveló que el porcentaje de niños libres de caries fue 0% en la comuna de Pirque y un 10% en Maipú, siendo esta diferencia significativa. No se encontró una diferencia estadísticamente significativa entre los índices ceo-d de las comunas Pirque (4,55) y Maipú (3,82). No obstante, el promedio de piezas obturadas fue mayor en Pirque, alcanzando significancia estadística. En el índice COP-D, se obtuvo una diferencia significativamente mayor en Pirque (2,65) respecto a Maipú (1,48). El desglose del índice muestra que los promedios de piezas dentarias cariadas y perdidas por caries fueron menores en Pirque, pero las diferencias no tuvieron significancia estadística. En cambio el promedio de piezas obturadas, fue significativamente mayor para la comuna de Pirque. Estos resultados indican que, el aporte de F - , entregado desde 1º Básico a través del PAE-F a los niños examinados de 8 años de Pirque, no generó una menor prevalencia y severidad de caries dental en estos niños, en relación a los de Maipú, de la misma edad y no cubiertos por el PAE-F.
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Carlsson, Peter. "On the epidemiology of mutans streptococci." Malmö : Dept. of Cariology, Faculty of Odontology, University of Lund, 1988. http://catalog.hathitrust.org/api/volumes/oclc/17942744.html.
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Bule, George Fairley. "Survey of dental caries experience of 6, 9 and 11 year old ni-vanuatu school children in vila." Thesis, Faculty of Dentistry, 1986. http://hdl.handle.net/2123/4279.
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Wu, Isabel. "Early childhood caries and its possible related factors in Macau." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B26196219.
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Sundin, Birgitta. "Dental caries and sugar-containing products analytical studies in teenagers /." Malmö [Sweden] : Dept. of Pedodontics, Faculty of Odontology, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/32290695.html.
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Medina, Castro José Francisco. "Prevalencia de caries dental y necesidad de tratamiento en pacientes adultos con demanda de atención diagnóstica." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2009. https://hdl.handle.net/20.500.12672/2194.
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Objetivo. El propósito del presente estudio de determinar la prevalencia de caries dental y necesidad de tratamiento.
Método. Se examinaron 200 individuos de edades comprendidas entre los 20 y 64 años, dividiéndolos por género y grupos etáreo valorando su estado con el índice CPOD y de necesidad de tratamiento.
Resultados. Se obtuvo que el 95,5%, de los individuos fueron afectados por caries. Los resultados obtenidos fueron de un índice CPOD poblacional de 14,05. El promedio de piezas dentales por cada tratamiento requerido para Sellante 14,66% de las piezas; Obturación con una superficie 13,94%; obturación con más de dos superficies 3,47%; coronas 9,02; tratamiento pulpar 0,23%; extracción 1,47%, prótesis parciales removibles con un 3% y prótesis completa 1%.
Conclusión. El índice CPOD general fue 14,05, siendo considerado como grave según los parámetros de la OMS. La mayor necesidad de tratamiento fue para la necesidad de sellador en el grupo de 20 a 24 y la menor (cero) para el tratamiento pulpar en los grupos de 45 a 54 y 55 a 64. La mayor necesidad de tratamiento de prótesis removible fue para las prótesis parciales removibles con un 3%.Objective: To determine the prevalence of dental caries, likewise to establish the treatment needs. Method: A cross sectional study in 200 subjects aged 20 to 64 years, all subjects were divided in groups, by age and gender, to evaluate their states according to DMFT index and treatment needs. Results: The 95.5% of subjects were affected by dental caries. Results were gotten from a DMFT population index of 14,05. An average of 14,66% of teeth required Sealant treatments, An average of 13,94% required Filling one surface, the 3,47% required Filling more than two surfaces, the 9,02% required Crowns, the 0,23% required Pulp treatments, the 1,47% required Extractions, the 3% required Removable partial dental prosthesis and the 1% required Removable total dental prosthesis Conclusion: The overall DMFT was 14.05, which is considered as a serious problem according to World Health Organization (WHO) guidelines. The most needed treatment was for Sealant treatments, in the group aged 20 to 24 years, and the less needed treatment (Zero) was for Pulp treatments in the group aged 45 to 54 years and 55 to 64 years. Finally, the most needed treatment in Removable prosthesis was for Removable partial dental prosthesis with 3%.
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Lo, Chin-man Edward, and 盧展民. "Dental caries among Hong Kong children: a socio-epidemiological study." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1987. http://hub.hku.hk/bib/B31953876.
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Bascuñán, Droppelmann Marlys Verena. "Comparación de algunas características salivales en niños con caries temprana de la infancia y niños sin caries temprana de la infancia." Tesis, Universidad de Chile, 2013. http://www.repositorio.uchile.cl/handle/2250/117401.
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Trabajo de Investigación Requisito para optar al Título de Cirujano DentistaIntroducción: La Caries Temprana de la Infancia (CTI) es una forma única de caries que se desarrolla en la dentición temporal. Tiene una etiología multifactorial, y aunque es clasificada como una enfermedad crónica e infecciosa, la influencia de otros factores puede modificar cómo los tejidos dentarios reaccionan a los desechos ácidos producidos por las bacterias. Uno de estos factores, es la saliva, que tiene un importante efecto protector contra la caries dental cuando sus múltiples características y funciones están normales. Objetivo: Comparar algunas características salivales en niños con Caries Temprana de la Infancia y niños sin CTI. Materiales y Métodos: Estudio de tipo observacional transversal de caso – control. Se examinaron 77 preescolares de 37 a 72 meses de edad (12 con CTI, 26 con CTI-S y 39 sin CTI) a los cuales se les recolectó saliva estimulada. El pH y capacidad buffer fue determinado mediante uso de un microelectródo de pH, la velocidad de flujo salival fue evaluada con una fórmula que involucra volumen, el tiempo de recolección y el peso específico de la saliva. Fluoruro fue determinado mediante métodos de potenciometría, y fosfato a través de técnicas de absorción espectrofotométricas colorimétricas. Para la determinación de normalidad de la distribución de datos se utilizó el test Shapiro Wilk. Todas las variables salivales medidas no presentaron distribución normal. Para las comparaciones de ellas entre los grupos de niños con CTI y sin CTI se utilizó test de Mann-Whitney. Para las comparaciones de ellas entre los grupos de niños con CTI, CTI-S y sin CTI se utilizó test de Kruskal-Wallis. Para la determinación de significancia estadística entre CTI y los factores de riesgo se implementó Chi². La asociación entre los factores de riesgo y prevalencia de CTI se determinó través de análisis de regresión logística. Resultados: No hubo diferencia significativa en ninguna variable salival medida en niños con CTI, CTI-S y sin CTI (p>0.05). Una menor educación de la I madre es el factor de riesgo más importante de CTI, seguido por el uso de biberón y una menor frecuencia de cepillado dental. Conclusiones: Los resultados obtenidos indican que no hay diferencias estadísticamente significativas de pH, capacidad buffer, velocidad de flujo salival, y niveles de fluoruro y fosfato, en niños con CTI, CTI-S y sin CTI. Los factores de riesgo asociados a CTI, como la educación de la madre, el uso de biberón, la frecuencia de cepillado y la atención dental previa del niño son más importantes al momento de desarrollar CTI que algunas variables salivales.
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Hoppenbrouwers, Petrus Michiel Maria. "Root caries and the inhibiting effect of fluoride." [S.l. : s.n.], 1990. http://catalog.hathitrust.org/api/volumes/oclc/22995610.html.
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Lo, Chin-man Edward. "Dental caries among Hong Kong children a socio-epidemiological study /." Click to view the E-thesis via HKUTO, 1987. http://sunzi.lib.hku.hk/hkuto/record/B31953876.
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Auad, Sheyla MaÌrcia. "Dental erosion in Brazilian schoolchildren and its association with dental caries and potential risk factors." Thesis, University of Newcastle Upon Tyne, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430636.
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Pramono, Dibyo. "Trends of dental caries prevalence in Australian and Indonesian schoolchildren." Thesis, The University of Sydney, 1989. http://hdl.handle.net/2123/4901.
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Rosén, Linda. "Dental caries and background factors in children with heart disease." Doctoral thesis, Umeå universitet, Pedodonti, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-39655.
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Congenital heart disease (CHD) is one of the most common congenital anomalies with an incidence of approximately 8–10 cases per 1000 live births. Technical development and continuing improvement in surgical methods have led to early interventions and an increased survival and consequently also a new group of patients in dentistry. The general aim of this thesis was to study the caries prevalence and some possible background factors in children with complex CHD.Paper I examined the caries prevalence in 41 children with complex CHD and 41 healthy age- and gender-matched controls. CHD children had higher dmfs-values 5.2 ± 7.0 vs. 2.2 ± 3.5 in the controls (p < 0.05). CHD children on digoxin medication had higher dmfs values 10.1 ± 8.5 vs. 3.7 ± 5.3 in the other CHD children (p < 0.05). CHD children had received more fluoride varnish treatments and fluoride tablets (p < 0.01).Paper II investigated attitudes and experiences of dental health information and advice, dental care, and service in 33 parents of children with complex CHD and 33 parents of age- and gender-matched controls. Differences were displayed in the professional group that provided the parents with dental health information and advice, attitudes to reception at the dental clinic, and experience of sedation before operative dental treatment (p < 0.05).Paper III examined 183 Swedish general dentists’ experiences of and attitudes to dental care for children with CHD. Eighteen % of the dentists had received special education or information to treat children with CHD, while almost half of the dentists had one or more patients with CHD and a majority of them stated that their CHD patients had a caries problem. The dentists had a different opinion regarding the provision of dental treatment for children with CHD compared to the current situation (p < 0.001).Paper IV studied salivary secretion, salivary buffering capacity, viable count of bacteria (TVC), mutans streptococci (MS) and lactobacilli (LBC), calcium, chloride, magnesium, potassium, sodium, and IgA in 24 children on heart failure medication and 24 healthy controls. Seven children (29 %) had stimulated secretions below 0.5 ml/min compared to no child among the controls (p < 0.01). TVC were 1.4 × 106 ± 1.2 × 107 in the cardiac group vs. 2.7 × 106 ± 2.9 × 107 in the control group (p < 0.05). MS ratio of TVC constituted 0.11 ± 0.35 % vs. 0.01 ± 0.02 % for the controls (p > 0.05).Paper V studied the endogenous pH and titratable acidity and dissolution of calcium and phosphate from dental hard tissues by 13 pharmaceutical preparations used in paediatric cardiology. Six of the preparations had an endogenous pH below the critical value for enamel dissolution.It is concluded that (i) children with complex CHD had a higher caries experience in the primary dentition than healthy matched controls, (ii) children on digoxin medication had a higher caries experience than other children with complex CHD, (iii) children with complex CHD had received more caries prevention than healthy controls, (iv) parents of children with complex CHD were less satisfied with the reception and care they received than parents of healthy children, (v) general dentists had a different opinion regarding the provision of dental treatment to children with CHD compared to the current situation (vi) children on heart failure medication can have a low saliva secretion, (vii) pharmaceutical preparations used on long-term basis in paediatric cardiology may pose a hazardous threat to dental hard tissues due to their acidity.
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Johansson, Elisabeth. "Effect of ozone on dental caries and on cariogenic microorganisms." Doctoral thesis, Umeå universitet, Institutionen för odontologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-59066.
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There are a number of unanswered questions regarding new caries preventive methods such as ozone treatment as well as novel caries detection methods that monitor and evaluate these preventive methods. This thesis seeks answers to some of these questions. Aims: Paper I investigates the in vitro sealing capacity of a novel ozone delivery system and its re-suction capacity. Paper II studies the in vitro antibacterial effect of ozone on cariogenic bacterial species with and without the presence of saliva and its possible effect on the saliva proteins. Paper III assesses the in vitro validity of laser-induced fluorescence (LF) measurements, visual inspection (colour), and tactile examination (surface texture) on root caries lesions and correlates these with histopathological measurements of lesion depths. In addition, Paper III investigates how inter-device, inter-examiner, and intra-examiner levels influence LF reading agreements and whether lesion colour and surface texture influences LF readings. Paper IV evaluates the in vivo effect of ozone and fluoride varnish treatments on occlusal caries in primary molars. Material and methods: Paper I: Full ozone application cycles, including the re-suction period, and interrupted cycles with displacement of the cup during the delivery cycle were studied using an ozone air analyser. Paper II: Ozone gas was exposed to the bacteria in the solution’s buffer and saliva via a tube connected to the ozone generator for 10, 30, and 60 seconds. Paper III: Calibrated examiners assessed lesion colour and surface texture and performed measurements with two LF devices for three separate one-week intervals. Sections (300µm thick) of 64 out of 93 teeth were obtained and examined under a microscope. Lesion depth was assessed with two references: from the delineated borderline of the original exposed root surface (ref I) or, if loss of surface continuity, the absolute lesion depth (ref II). Paper IV: The split mouth study was conducted in two parts. The participants in part A were children (mean age 4.8 years) with medium-high caries risk. Inclusion criteria were bilateral matched pairs of cavitated or non-cavitated occlusal lesions in primary molars (Ekstrand index score ≤ 3). Children in part B (mean age 4.5 years) with low-medium caries risk had pairs of non-cavitated lesions only (Ekstrand index score ≤ 2a). The assessments and treatments with ozone and fluoride varnish were performed at baseline and at three, six, and nine months. At the 12-month follow-up, only assessments were performed. Results: Paper I: Ozone leakage levels varied between 5.2 and 9.8 µg/m3. Paper II: In the salt buffer, 92%, 73%, and 64% of the initial numbers of A. naeslundii, S. mutans, and L. casei, respectively, were killed after 10 s ozone exposure and approximately 99.9% of the bacteria were dead after a 60 s exposure. After 10 and 30 s but not after 60 s exposure to ozone, S. mutans and L. casei were less efficiently killed in saliva compared to in the salt buffer. Various saliva proteins were degraded by ozone after the 60 s exposure. Paper III: The correlation between LF readings and histological depth was low with values ranging from 0.22 (p ˃ 0.05) to 0.31 (p < 0.05). The LF devices were significantly correlated with discolouration and with a surface texture denoted as hard. A significant correlation was found between colour and histological depth. No significant correlation was found between surface texture and histological depth. The reliability, evaluated as intra-class correlation coefficient, was 0.99 for intra-examiner, 0.97 for inter-examiner, and 0.98 inter-device level. Large differences were found between two consecutive measurements and high measurement errors indicated considerable deviation of individual measurements.Paper IV: In the first 15 pairs of part A, eight lesions treated with ozone and nine treated with fluoride, including all cavitated lesions, progressed to failure, i.e., required operative treatment during the study time. Due to non-acceptable results, the sample collection was discontinued because of ethical reasons. In part B, of 35 pairs, one of the ozone treated lesions failed at 12 months. A small shift towards increased VI scores was recorded for both ozone and fluoride lesions in this second part. Conclusions: - The ozone delivery system can be considered a safe system with low leakage levels in air, also with accidental displacements. - The cariogenic species S. mutans, L. casei, and A. naeslundii were sensitive to ozone gas treatment. The presence of saliva hampered the antibacterial effect of ozone. A low correlation between the LF readings and the histopathological depth of root caries lesions was shown. The LF device was found not to be appropriate for application to root caries diagnosis. - Neither ozone nor fluoride varnish treatments arrested the progression of cavitated occlusal caries lesions. In low and medium caries risk children non-cavitated occlusal lesions remained mainly unchanged during the study period. No difference in the effect of ozone and fluoride varnish treatments on occlusal caries in primary molars was seen.
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Alammari, Manal Rahma. "Investigation of dental caries using quantitative light-induced fluorescence (QLF)." Thesis, University of Liverpool, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539738.
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