Academic literature on the topic 'Dementia – Diagnosis'

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Journal articles on the topic "Dementia – Diagnosis"

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Salardini, Arash. "Interpretation of Biomarker Data in Diagnosis of Primary Dementias." Seminars in Neurology 39, no. 02 (March 29, 2019): 200–212. http://dx.doi.org/10.1055/s-0039-1683380.

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AbstractIn the last few years, an improved understanding of dementia biomarkers has significantly increased the diagnostic accuracy for dementias. The National Institutes of Health Biomarkers Definitions Working Group defines a biomarker as “a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention.” In the field of dementia, a biomarker is a biological measure pointing to a specific dementing pathology. Dementia biomarkers may also serve as surrogates for disease progression and as endpoints in clinical trials. Dementia biomarkers are best characterized for Alzheimer's disease, which is the most common form of primary dementia. The current “biological” conception of Alzheimer's disease is based on consideration of three biomarkers: amyloid, tau, and “neurodegeneration.” The status of these biomarkers may be determined by cerebrospinal fluid clinical chemistry or imaging. Biomarkers for other primary dementias are less reliable and rely chiefly on structural and functional imaging. When appropriate, genetic testing may help with diagnostic certainty in hereditary forms of dementia.
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Chahyani, Wiwit Ida, and Murni Sri Hastuti. "Mixed Dementia: Tinjauan Diagnosis dan Tatalaksana." Muhammadiyah Journal of Geriatric 1, no. 2 (January 5, 2021): 46. http://dx.doi.org/10.24853/mujg.1.2.46-51.

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Latar Belakang: Prevalensi demensia saat ini semakin meningkat, mengenai usia diatas 65 tahun dan risikonya meningkat 2 kali setiap penambahan usia 5 tahun. Salah satu bentuk demensia adalah mixed dementia. Diagnosis mixed dementia sangat sulit dan memberikan tantangan tersendiri bagi para klinisi. Pada artikel ini, penulis ingin membahas mengenai tinjauan diagnosis dan tatalaksana mixed dementia. Hasil: Diagnosis mixed dementia dapat menggunakan beberapa kriteria yaitu International Classification of Diseases and Health Related Problems 10th Revision (ICD-10), the Alzheimer’s Disease Diagnostic and Treatment Centers (ADDTC), dan the National Institute of Neurological Disorders and Stroke and Association Internationale pour la Recherche et l’Enseignement en Neurosciences (NINDS-AIREN). Tatalaksana mixed dementia berupa terapi farmakologi untuk gejala gangguan kognitif dengan pemberian golongan inhibitor kolinesterase dan antagonis NMDA. Terapi farmakologi untuk gangguan psikis dan perilaku dengan antipsikotik atau antidepresan. Managemen faktor risiko hipertensi, konsumsi nutrisi yang sehat, dan olah raga teratur sebagai upaya preventif dan mencegah progresivitas mixed dementia. Kesimpulan: Diagnosis mixed dementia meliputi gejala demensia Alzheimer dan demensia pada penyakit serebrovaskuler. Tatalaksana mixed dementia meliputi terapi gangguan kognitif, psikis, dan perilaku, serta tatalaksana faktor risiko penyakit serebrovaskuler. Dibutuhkan penelitian lebih lanjut serta adanya konsensus diagnosis dan tatalaksana mixed dementia baik nasional maupun internasional agar tercapai tatalaksana secara komprehensif.
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Snowden, JS. "Neuropsychological evaluation and the diagnosis and differential diagnosis of dementia." Reviews in Clinical Gerontology 9, no. 1 (February 1999): 65–72. http://dx.doi.org/10.1017/s0959259899009168.

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Dementia has traditionally been viewed as a global, undifferentiated impairment of intellect and memory. The implication is that patients with dementia share a common clinical syndrome. It is, however, now recognized that different dementing diseases give rise to distinct patterns of mental change, reflecting differences in the topographical distribution of pathological change within the brain. Contrary to the traditional view, analysis of the characteristics of dementia can contribute substantially to differential diagnosis. Indeed, since many patients with a dementing illness exhibit few physical signs, evaluation of the mental changes may be critical to diagnostic accuracy. With the advent of new therapies for dementia, precise diagnosis has become increasingly important. Moreover, understanding of patients’ symptom pattern provides a rational basis for patient management and for advice to carers.
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de Mendonça Lima, C. A. "Diagnosis and differential diagnosis of dementia." European Psychiatry 26, S2 (March 2011): 2108. http://dx.doi.org/10.1016/s0924-9338(11)73811-1.

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The European prevalence of dementias will increase of 40% during the next 40 years, with serious effects on families, communities and healthcare systems (1).A correct diagnosis of dementia is the first step to plan treatment, care and support. There is no single test to identify the cause of dementia. The diagnostic process involves, medical history, mental status exam, physical exam, laboratory tests, psychiatric and (neuro)psychological tests and assessment of individual's functioning. An image of brain is suitable.There is an idea that this diagnostic process can only be realized by highly specialized staff. WHO has recently published the mhGAP Intervention Guide for use in non-specialized health-care settings by health-care providers working at first- and second-level facilities. It includes guidance on evidence-based interventions to make the diagnosis and manage a number of priority conditions, including dementia (2).The recent progress in pathological process understanding of Alzheimer's disease (AD), may help to the proposal of new research criteria that reconceptualise the diagnosis around both a specific pattern of cognitive changes and structural/biological evidence of Alzheimer's pathology (3).These two recent developments are significant contributions to increase the accessibility to a proper diagnosis and care of dementia around the world.
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Mahalingam, Sowmya, and Ming-Kai Chen. "Neuroimaging in Dementias." Seminars in Neurology 39, no. 02 (March 29, 2019): 188–99. http://dx.doi.org/10.1055/s-0039-1678580.

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AbstractDementia is a global health issue, the burden of which will worsen with an increasingly aging population. Alzheimer's disease (AD) is the most common dementia, with 50 to 60% of all dementias attributable to AD alone, while the rest are mostly due to frontotemporal lobar dementia, dementia with Lewy bodies, Parkinson's disease dementia, and vascular dementia. Diagnosis of dementias is made clinically with the aid of other testing modalities including neuroimaging. While the role of imaging has traditionally been to exclude reversible causes of dementia, positron emission tomography (PET) with 18-fluorine fluorodeoxyglucose and magnetic resonance imaging now are increasingly used more for definitive diagnosis of dementia in the prodromal stages and to aid with formulating the differential diagnoses. Introduction of molecular imaging modalities such as amyloid PET and tau PET have improved diagnostic certainty in the clinical trial setting and promise to find their way into the clinic in the near future. In this review, we will focus on the multimodality imaging of dementias especially AD and its differential diagnoses.
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Maxfield, Molly, Allie Peckham, Dara James, Laura Lathrop, and Amy Fiske. "ANTICIPATED SUICIDAL AND DEATH IDEATION IN RESPONSE TO AN IMAGINED DEMENTIA DIAGNOSIS." Innovation in Aging 6, Supplement_1 (November 1, 2022): 781. http://dx.doi.org/10.1093/geroni/igac059.2824.

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Abstract Alzheimer’s disease and related dementias are prevalent, incurable, and highly impactful diagnoses. Dementias are therefore feared diagnoses. Dementia-related anxiety (DRA) is anxiety about a current or future diagnosis of dementia and the associated complex symptoms. In a mixed methods study, semi-structured interviews were conducted to identify causes of DRA and revealed that numerous adults anticipated suicidal or death ideation if diagnosed with dementia. Fifty cognitively healthy, community-dwelling adults aged 58 to 89 (M = 70.92, SD = 6.08; 64% female) were recruited from a university participant registry and Memory Clinic. Among participants endorsing anticipated suicidal or death ideation, responses ranged from active plans, including interest in physician-assisted suicide, to more passive wishes to hasten death rather than continue to live with dementia. Within reports of both anticipated suicidal and death ideation, subthemes emerged, including the concern about becoming a burden to others in more advanced stages of dementia, the devaluation of life or the self with dementia, and the desire for (and anticipated thwarting of) control and independence. Statements of anticipated suicidal and death ideation were contingent on a future dementia diagnosis and may reflect errors in affective forecasting. Nevertheless, given the prevalence of dementias and older adults’ elevated rates of suicide, the intersection of these two public health issues warrants greater attention and further investigation.
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Tierney, M. C., W. G. Snow, and R. H. Fisher. "Dementia diagnosis." Neurology 39, no. 11 (November 1, 1989): 1560. http://dx.doi.org/10.1212/wnl.39.11.1560.

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Rai, G. S., and I. Blackman. "Dementia Diagnosis." Clinical Gerontologist 19, no. 4 (December 9, 1998): 68–70. http://dx.doi.org/10.1300/j018v19n04_07.

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Testa, H. J., J. S. Snowden, D. Neary, R. A. Shields, A. W. I. Burjan, M. C. Prescott, B. Northen, and P. Goulding. "The Use of [99mTc]-HM-PAO in the Diagnosis of Primary Degenerative Dementia." Journal of Cerebral Blood Flow & Metabolism 8, no. 1_suppl (December 1988): S123—S126. http://dx.doi.org/10.1038/jcbfm.1988.42.

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The clinical value of single photon emission computed tomography (SPECT) in the differential diagnosis of dementia due to cerebral atrophy was evaluated by comparing the pattern of distribution [99mTc]–HM-PAO in three dementing conditions. Imaging was carried out in 26 patients with suspected Alzheimer's disease, 14 with dementia of the frontal-lobe type, and 13 with progressive supranuclear palsy. Images were evaluated and reported without knowledge of clinical diagnosis with respect to regions of reduced uptake of tracer. Reduced uptake in the posterior cerebral hemispheres was characteristic of Alzheimer's disease, while selective anterior hemisphere abnormalities characterized both dementia of the frontal-lobe type and progressive supranuclear palsy. The latter conditions could be distinguished on the basis of the appearance of integrity of the rim of the frontal cortex. The technique has an important role in the differentiation of degenerative dementias.
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Chertkow, H., H. Bergman, H. M. Schipper, A. M. Clarfield, S. Gauthier, S. Fontaine, and R. Bouchard. "Assessment of Suspected Dementia." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 28, S1 (May 2001): S28—S41. http://dx.doi.org/10.1017/s0317167100001189.

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At the Second Canadian Consensus Conference on Dementia (CCCD) (February, 1998), a group of neurologists, geriatricians, and psychiatrists met to consider guidelines for evaluation of dementia in Canada. This review paper formed a background paper for their discussion of dementia diagnosis. These experts from across the country concluded that diagnosis of suspected dementia cases continued to rest on skilled clinical assessment. Mental status exam, preferably in some quantifiable form, has become an essential part of the assessment. Selected laboratory tests are advisable in all cases (CBC, TSH, electrolytes, calcium, and glucose), but the CCCD continued to advise that CT scanning was mandatory only in selected cases where clinical findings pointed to another possibility besides Alzheimer’s disease. The growing list of other diagnostic measures with potential usefulness in diagnosis of Alzheimer’s disease or dementia in general was reviewed, but the evidence was judged as insufficient to support routine use of these tests by physicians. As new treatments for Alzheimer’s disease become available, neurologists face new diagnostic challenges - differentiating Mild Cognitive Impairment, Frontotemporal dementias and Mixed dementias, and Lewy Body Dementia. Guidelines to aid in differential diagnosis are presented.
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Dissertations / Theses on the topic "Dementia – Diagnosis"

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Dooley, Jemima Mary Beatrice. "Communicating a diagnosis of dementia." Thesis, University of Exeter, 2016. http://hdl.handle.net/10871/27939.

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Background: There has been a rise in dementia awareness, with policy changes leading to increased diagnosis rates. However, the stigma of dementia is likely to cause challenges in diagnostic communication. This is complicated by the effect of dementia on cognitive functioning. The aims of this study were to (1) identify how diagnoses of dementia are communicated, (2) identify how people with dementia respond to the diagnosis, and (3) explore doctors’ perspectives on dementia diagnosis delivery. Methodology: A systematic literature review was conducted. Twenty doctors from 9 memory clinics across 4 NHS trusts participated. Eighty-one dementia diagnosis feedback meetings were video-recorded. Conversation analysis was used to identify patterns in diagnosis delivery. Four focus groups with the participating doctors were analysed using thematic analysis (inter-rater reliability 0.89). Findings: The literature review highlighted the dilemma of communicating both sensitively and honestly with people with dementia, as well as challenges stemming from cognitive impairment. This was also evident in diagnostic communication. Prior to diagnosis doctors elicited patient orientation to the meeting purpose (“do you know why you’re here?) and perspective into symptoms (“how is your memory?”). The majority of patients displayed some confusion as to the meeting purpose and offered non-medicalised explanations for their symptoms. Doctors attempted to address this through repeated explication of test results and statements of the clinic purpose. Dementia was always explicitly named. Diagnoses were often delivered indirectly (“that is dementia”), a practice to manage patient resistance and negative responses. However, over 40% were delivered directly (“you have dementia”), especially when patients were more cognitively impaired. Doctors pursued non-minimal responses to diagnosis, apparently to obtain perspective before progressing to treatment. However, resistance was not always addressed and prognosis was often avoided. Doctors highlighted pressure to make diagnoses and an aim to emphasise “living well” rather than discussing prognosis. Conclusion: The findings of this study highlighted the delicate balance between minimising likely resistance and distress and maximising understanding in the context of cognitive impairment. Instilling hope is evidently a priority for doctors. The diagnosis meeting is just one part of the journey of the person with dementia, and sufficient pre- and post-diagnosis support is integral.
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Verhey, Franciscus Rochus Jozef. "Dementia, depression and forgetfulness clinical studies of the early diagnosis and the differential diagnosis of dementia /." Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Maastricht University [Host], 1993. http://arno.unimaas.nl/show.cgi?fid=5854.

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Everitt, Alaina. "Differential Scoring Patterns on the Clock Drawing Test: a Comparison of Vascular Dementia and Alzheimer's Dementia." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5283/.

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This study examined differences in scoring patterns among those diagnosed with Alzheimer's dementia and vascular dementia on the clock-drawing test. Archival clock drawing data was retrieved on 279 patients presenting at a county hospital-based memory clinic. Analysis of drawings was based on frequency of qualitative errors, as well as an overall quantitative score. Mean comparisons found those patients with Alzheimer's dementia to perform worse on both quantitative and qualitative scoring measures. However, Pearson's chi-squared test revealed a significantly higher rate of spacing errors among subjects with vascular dementia. Such lends support to my hypothesis that impaired executive functioning in vascular dementia patients would lead to poor qualitative performance. Logistic regression found significant predictive ability for the qualitative criteria in diagnosis (χ2 = 25.49, p < .001), particularly the rate of omission (z = 8.96, p = .003) and addition errors (z = 7.58, p = .006). Such findings hold important implications for the use of qualitative criteria in cognitive screening assessments.
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Aslaksen, Jonasson Alexander, and Alfred Wahlforss. "Diagnosis of Dementia using Transformer Models." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-279226.

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Dementia is a syndrome of illnesses resulting in cognitive decline, severely impacting the lives of those afflicted as well as their loved ones. The most common form of dementia is Alzheimer's disease, with roughly 10 million new cases each year. In this study we examine different machine learning models and approaches aimed to aid healthcare professionals in early diagnosis of Alzheimer's disease, potentially automating parts of the diagnostic process. We evaluate our models on the Pitt corpus of the Dementia Bank dataset, using 10-fold cross validation. We compare the BERT and RoBERTa transformer models, and find that both models achieve high accuracy, precision, and specificity. The highest accuracy is achieved by RoBERTa, reaching an accuracy of 86.72%, a precision of 90.69% and a specificity of 90.53%. Furthermore, we explore the viability of using automated speech recognition for automatic transcription of audio samples from patient meetings. RoBERTa achieves an accuracy of 83.59% using transcripts generated by Google's automatic speech recognition, suggesting such methods may be viable for automating certain parts of the diagnostic process. In addition to the exploration of transformer models and their viability for dementia diagnostics, this paper provides a market analysis of a potential automated diagnostics tool utilizing transformer models. The analysis is based on a literature study and on two interviews; one with the CEO of a start-up providing automated dementia tests for healthcare professionals, and one with a psychologist researching dementia as well as potential methods of early diagnosis of dementia. With the interviews and literature study as a basis, we use the SWOT framework, and PEST analysis along with Porter's five forces framework to analyse the current market potential for such an automated tool. Despite detecting several obstacles and difficulties prior to market entry, we find significant potential for such a product given the current state of the market.
Demens är ett syndrom av sjukdomar som orsakar kognitiv nedsättning och påverkar både de drabbade och deras familjer. Den vanligaste typen av demens ar Alzheimers sjukdom, med cirka 10 miljoner nya fall per ar. I denna studie undersöker vi olika maskininlärningsmodeller och tillvägagångssätt i syfte att underlätta får sjukvårdspersonal att ställa en tidig diag­nos, och möjligtvis att även kunna automatisera vissa delar av diagnosprocessen. Vi utvärderar vara modeller på Pitt­corpuset i DementiaBank-datasetet och använder 10-delad ko­rsvalidering. Vi jämför två transformer-modeller: BERT och RoBERTa, och finner att bada modeller åstadkommer goda resultat avseende noggrannhet, precision, specificitet och sen­sitivitet. Den högsta noggrannheten uppnås av RoBERTa, på 86.72%, en precision på 90.69%, och en specificitet på 90.53%. Vidare undersöker vi gångbarheten i att använda automatisk taligenkänning for automatiserad transkribering av ljudinspel­ningar från patientmoten. RoBERTa uppnår da en noggrannhet på 83.59% när den använder transkriberad text från Googles automatiska taligenkänningstjänst, vilket tyder på att sådana metoder kan vara gångbara for att automatisera vissa delar av den diagnostiska processen. Förutom undersökning av transformermodeller bidrar detta verk även med en marknadsanalys av marknadspotentialen får ett verktyg får automatiserad demensdiagnostik. Analysen baseras på en litteraturstudie och två intervjuer; en med en VD får en start-upp som erbjuder liknande tjänster, och en intervju med en forskare inom demens. Med litteraturstudien och de två intervjuerna som grund analyserar vi marknadspotentialen med tre ramverk: Porters fem krafter, PEST-analys och SWOT­analys. Vi fastslår att det trots flertal hinder och svårigheter får marknadsinträde finns det stor potential och en stor efterfrågan på en sådan produkt.
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McKeith, Ian G. "The clinical diagnosis of Lewy body dementia." Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333615.

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Smith, Fiona. "The experience of receiving a diagnosis of dementia." Thesis, University of Sheffield, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412460.

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Green, Alison Jane Ellen. "Brain-specific proteins in the diagnosis of dementia." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313354.

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Taylor, Rachel Jane. "Being given a diagnosis of dementia : the experiences of people with dementia and people who care for someone with dementia." Thesis, Open University, 1996. http://oro.open.ac.uk/57649/.

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This study explores the issues raised for people with dementia and their carers when they receive a diagnosis of dementia. Previous research suggests that more people with dementia than other serious illnesses such as cancer will not be told their diagnosis. The implications of this for the way that people with dementia adjust psychologically to their situation are reviewed. It is suggested that the complex illness concept and the particular nature of dementia as an illness influence communication about it The research had three groups of participants. Twenty-six people caring for a relative with dementia completed a short survey. Two people with dementia and seven people caring for someone with dementia were interviewed face-to-face to gather in-depth information about their experiences of receiving and coping with a diagnosis. Grounded theory was used to analyse the interviews and a descriptive summary of the survey was produced. The survey confirmed that many people with dementia do not get told their diagnosis. The interviews described the issues raised for people with dementia, such as the feelings raised for them by having dementia and highlighted their ways of coping with dementia. The interviews with carers suggested that if sharing was an issue, the carers tried to strike a balance between remaining honest and protecting the person from the implications of the knowledge. Maintaining a sense of hope for the person seemed to be very important. A critical discussion of the methodology is presented. The implications for future research and the clinical relevance of the research are also discussed.
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Mychalkiw, Wasyl. "Short-term visual retention as an index of dementia." Thesis, Keele University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279822.

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Douglas, Jane E. "Living with and beyond dementia : a phenomenological investigation of young people's lived experience with dementia and the transition from pre-diagnosis through diagnosis and beyond to living well with dementia." Thesis, Edinburgh Napier University, 2017. http://researchrepository.napier.ac.uk/Output/1032617.

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Younger People with Dementia (YPwD) are those who receive a diagnosis of dementia under the age of 65. In Scotland the number of people with dementia who meet this definition is approximately 3200 (Alzheimer Scotland, 2017). The purpose of this study was to explore the human experience of living with dementia at a younger age and to consider interpretations of well-being as defined by the subjective experience of the participants. At the start of this study there was limited quality research available which explored the lives and experiences of YPwD. At that time there was some recognition within professional groups and practitioners that YPwD would benefit from age appropriate services. This study used an Interpretive Phenomenological design to explore the experiences of YPwD and used in-depth qualitative interviews with eight people who were diagnosed with dementia under the age of 65, to capture their journey through pre-diagnosis, diagnosis and beyond. Interpretive Phenomenological Analysis was utilised for the primary analysis. A secondary analysis was then conducted with the initial findings using Self-determination Theory, Basic Psychological Needs Theory, autonomy, competence and relatedness to identify areas of well-being. The study identified four superordinate themes situated within a four phase transition pathway, which identified how a diagnosis of dementia impacted on the person and the process they underwent following diagnosis. These are:pre-diagnosis phase, living in a changing world, awareness of the changing self, discombobulation; diagnostic phase, anger and relief, the fragmented self, consideration; post diagnostic phase, the challenge of learning to livewith dementia as a younger person, the evolving self, assimilation; and the phase living well beyond dementia, consolidated self, consolidation. The study highlighted that while having a diagnosis of dementia at a younger age is a challenging and devastating experience, it is possible to live a good and productive life beyond the diagnosis of dementia. The secondary analysis using Self-determination Theory, Basic Psychological Needs Theory identified that where the basic psychological needs were supported, this enabled participants to embrace their lives living with and beyond dementia with improved wellbeing. The findings suggest that the basic psychological needs were thwarted in the pre-diagnostic phase and during and immediately after diagnosis, creating feelings of ill-being. The study acknowledges the strong sense of identity around the younger person with dementia and suggests that this group perceive their dementia, and the support they need to live with the condition to be a different experience to that of older people. The ability of a number of the participants to live an active life within a supported community cannot be underestimated, and suggests that this area of care and support needs to be evaluated in light of the changing needs of people living with dementia, particularly those who are diagnosed at such an early part of their lifecycle.
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Books on the topic "Dementia – Diagnosis"

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1953-, Maj Mario, and Sartorius N, eds. Dementia. 2nd ed. Chichester: Wiley, 2002.

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1953-, Maj Mario, and Sartorius N, eds. Dementia. Chichester: John Wiley, 2000.

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Grossberg, George T., and Charles Cefalu. Diagnosis and management of dementia. Leawood, KS: American Academy of Family Physicians, 2001.

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Erkinjuntti, Timo. Dementia: Clinical diagnosis and differential diagnosis, with special reference to multi-infarct dementia. Helsinki: Miktor, 1988.

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Dementia. New York: Plenum Press, 1993.

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Dargan, Kyle. Logorrhea dementia: A self-diagnosis : poems. Athens: University of Georgia Press, 2010.

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Logorrhea dementia: A self-diagnosis : poems. Athens: University of Georgia Press, 2010.

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B, Emery V. Olga, and Oxman Thomas E, eds. Dementia: Presentations, differential diagnosis, and nosology. Baltimore: Johns Hopkins University Press, 1994.

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name, No. Dementia: Presentations, differential diagnosis, and nosology. 2nd ed. Baltimore, MD: Johns Hopkins University Press, 2003.

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Bergener, Manfred, and Barry Reisberg, eds. Diagnosis and Treatment of Senile Dementia. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-46658-8.

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Book chapters on the topic "Dementia – Diagnosis"

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Camicioli, Richard. "Diagnosis and Differential Diagnosis of Dementia." In Dementia, 1–13. Oxford: John Wiley & Sons Ltd, 2013. http://dx.doi.org/10.1002/9781118656082.ch1.

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Innes, Anthea, Lesley Calvert, and Gail Bowker. "Pre-Diagnosis." In Dementia, 9–20. Milton Park, Abingdon, Oxon; New York, NY : Routledge, 2020. | Series: The basics series: Routledge, 2020. http://dx.doi.org/10.4324/9781315709000-3.

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Edwards, Allen Jack. "Technology and Diagnosis." In Dementia, 55–76. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4757-9963-7_4.

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Lipton, Anne M. "After the Diagnosis." In Dementia, 97–110. Oxford: John Wiley & Sons Ltd, 2013. http://dx.doi.org/10.1002/9781118656082.ch7.

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Innes, Anthea, Lesley Calvert, and Gail Bowker. "Diagnosis of Dementia." In Dementia, 21–44. Milton Park, Abingdon, Oxon; New York, NY : Routledge, 2020. | Series: The basics series: Routledge, 2020. http://dx.doi.org/10.4324/9781315709000-4.

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McKeith, I. "The Differential Diagnosis of Dementia." In Dementia, 39–57. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-6805-6_3.

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Reisberg, Barry, Emile Franssen, Muhammad A. Shah, Jerzy Weigel, Maciej Bobinski, and Henryk M. Wisniewski. "Clinical Diagnosis of Dementia: A Review." In Dementia, 69–141. Chichester, UK: John Wiley & Sons, Ltd, 2002. http://dx.doi.org/10.1002/0470842350.ch2.

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Reisberg, Barry, Emile Franssen, Muhammad A. Shah, Jerzy Weigel, Maciej Bobinski, and Henryk M. Wisniewski. "Clinical Diagnosis of Dementia: A Review." In Dementia, 69–141. Chichester, UK: John Wiley & Sons, Ltd, 2003. http://dx.doi.org/10.1002/0470861878.ch2.

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Burns, A., and H. Förstl. "The Clinical Diagnosis of Alzheimer’s Disease." In Dementia, 309–26. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-6805-6_18.

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Merino, José G., and Vladimir Hachinski. "Diagnosis of Vascular Dementia." In Vascular Dementia, 57–71. Totowa, NJ: Humana Press, 2005. http://dx.doi.org/10.1385/1-59259-824-2:057.

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Conference papers on the topic "Dementia – Diagnosis"

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Ramos, Júlia Xavier, Bruno Zacarias, Breno Barbosa, and Simone Brandão. "18-FDG PET ANALYSYS FOR DEMENTIA DIAGNOSIS- BASELINE RESULTS FROM A REFERENCE CENTER IN RECIFE, BRAZIL." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda061.

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Background: Positrons emission tomography associated with computed tomography- PET/CT using the 18 F-fluorodeoxyglucose is a well-established exam for the medical evaluation of dementia, mainly helping in differential diagnosis to determine the specific type of dementia. Objectives: To describe the role of the PET/CT in the differential diagnosis of dementia in patients. Methods: a single-center, descriptive and records-based analysis of patients with Dementia evaluated in a clinic of Neurology at Recife and referred to PET/ CT due to diagnosis uncertainty, between 2020-2021. Results: 29 patients were included. The mean age was 65 years-old and 62% were female. Alzheimer’s dementia was the main diagnostic hypothesis (41.3%). PET/CT was suggestive of Alzheimer’s in 24%, Frontotemporal dementia in 21% and Lewy Bodies Dementia in 17% of patients. PET/CT results disagreed from clinical hypothesis in 21% o and in 10% it was inconclusive. In 38% it corroborated the clinical suspicion. Conclusions: in this sample the use of PET/CT FDG contributed to improve diagnostic accuracy in a significant subset of patients, mostly in the scenery of diagnostic uncertainty or atypical syndromes such as earlyonset dementias. A larger sample size and the continuation of this research will give us more information in the near future.
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Paiva, Mateus Coelho, Ana Júlia Santana Dornelas, Anne Caroline Castro Pereira, Bruna Paiva de França, Camila Nakamura Perissê Pereira, Camila Taveira de Castro, Catherine Rezende Vitoi, et al. "Complementary Exams for Dementia Diagnosis." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.269.

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Background: It is estimated that by 2050, over 130 million people will have dementia. These syndromes are neuropathologies that can be diagnosed with higher accuracy with a support of complementary exams. Objectives: Review literature about de importance of complementary exams for a better management of dementia syndromes. Methods: A search was carried out in the databases PubMed/MEDLINE, LILACS and Google Scholar using the DeCS descriptors: “dementia”, “mental status and dementia tests” and “diagnosis”. Nine articles, from 2005 to 2020, in English and Portuguese, were submitted to critical analysis. Results: A clinical evaluation, biomarkers and neuroimage techniques can improve diagnosis management of dementia syndromes. Changes in the early stages include memory loss. Therefore, Mini Mental State Exam can be used. The biomarkers include ß-amiloid and tau protein in the cerebrospinal fluid. Other exams can detect the lack of vitamin B12 and folate, hypothyroidism and infectious diseases. The computed tomography (CT) is fundamental to exclude secondary causes. In magnetic resonance the brain is seen atrophied. Conclusions: This review shows studies that indicate the relevance of complementary exams for the diagnosis of dementia. It could be seen that the association of molecular analysis and neuroimage can be benefic for a better diagnosis.
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Senna, Priscylla de, Wyllians Borelli, Wagner Brum, Eduardo Zimmer, Márcia Chaves, Arthur Schuh, and Raphael Castilhos. "FUNCTIONAL COGNITIVE DISORDER AS THE MOST FREQUENT DIAGNOSIS IN PUBLIC MEMORY CLINIC." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda059.

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Background: Functional cognitive disorder (FCD) has been described as a blind spot of dementia care. Objectives: Identify the frequency of FCD in a tertiary memory clinic (TMC). Methods: A retrospective analysis was conducted to identify new referrals from the primary care setting to a TMC from southern Brazil over 2014 to 2020. Diagnostic protocol included neurologic evaluation, cognitive screening, neuroimaging and laboratory testing. FCD was defined as cognitive complaints without objective cognitive decline, in the absence of evidence of neurodegenerative disease. Data is shown in mean (SD). Results: 516 patients (61% females, mean age 70.76±10.3 years) with a mean of 4.5 (+-3.94) years of education were referred. The diagnoses were: FCD (146, 28.3%); Alzheimer’s dementia (115, 22.3%); Mild Cognitive Impairment (51, 9.9%), vascular dementia (36, 7%); other types, including less common causes of dementia and rare pathologies (168, 7.6%). FCD patients were younger (66.2 (±9.4) vs. 72.6, p <0.001), and showed higher Geriatric Depression Scale than non-FCD patients (7.4 (±4.5) vs. 5.3 (±3.7), p <0.001). Education level did not differ. Conclusions: FCD was the most frequent diagnosis. Primary care strategies may greatly improve early diagnosis and treatment to these patients.
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Innocencio, Giovanna de Camargo, Paulo Roberto Hernandes Júnior, Juliana de Souza Rosa, Patrick de Abreu Cunha Lopes, and Jhoney Francieis Feitosa. "Epidemiological profile of Dementia in the state of São Paulo in the last 5 years." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.175.

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Background: dementia is a syndrome characterized by the presence of a progressive deficit in cognitive function, with interference in social and occupational activities, with risk factors varying with genetic and environmental stressors. The differential diagnosis must identify potentially reversible conditions, of different etiologies, such as metabolic changes, intoxications, and nutritional deficiencies. In primary degenerative dementias and sequelae forms, the etiological diagnosis carries therapeutic and prognostic implications. Objectives: to analyse the current epidemiological profile of dementia in the state of São Paulo in the last 5 years. Methods: a literature review was carried out based on articles available in the Scielo and PubMed database and an observational, descriptive and cross- sectional collection of epidemiological data on dementias available in DATASUS – SUS Hospital Information System (SIH/SUS) – in the last 5 years – January 2016 to December 2020 – assessing the number of hospitalizations, the amount of public spending, mortality rate and permanence. Results: in the analyzed period, 3.105 hospitalizations were observed due to occurrences related to dementia, representing a total expenditure of R$37.847.961,13, with 2017 being the year with the highest number of hospitalizations and responsible for the highest amount spent. The total mortality rate in the 5 years studied was 5,57, corresponding to 173 deaths, with 2020 being the year with the highest rate while 2017 had the lowest rate. The average of the permanence in the hospital was 180 days. Conclusion: patients with dementia need early diagnosis and procedures to reduce the rate of hospitalizations and mortality, as well as public costs. For this, technological innovations, using structural and functional neuroimaging methods, as well as biology and molecular genetics techniques, have presented perspectives for the early diagnosis of dementia.
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Formoso, Carolina Rodrigue, Raphael Machado Castilhos, Wyllians Vendramini Borelli, Matheus Zschornack Strelow, and Marcia Fagundes Chaves. "ANTICHOLINERGIC BURDEN IN DEMENTIA." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda031.

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Background: The anticholinergic burden is associated with a greater risk of functional/ cognitive decline and morbidity/mortality. Objectives: Our aim was to quantify the anticholinergic burden in the first visit in our dementia tertiary outpatient clinic. Methods: We performed a retrospective analysis of all first visit medical records of patients referred from primary health care to the outpatient dementia clinic of a tertiary hospital in Porto Alegre with a final diagnosis of dementia or Mild Cognitive Impairment (MCI) between 2014-2019. We evaluated all medications in use and we calculated a final score using Brazilian Anticholinergic Activity Drug (BAAD) score. This scale classified drugs according to its central anticholinergic activity from 1 to 3, with higher values indicating greater activity. The final score is the sum of the score for each drug. We divided the sample in two groups (score=0 and ⩾ 1) and performed a logist regression using age, sex, dementia diagnosis and MMSE as covariates. Results: We identified 199 final diagnoses of dementia (mostly Alzheimer’s Disease (AD) [45.2%]) and 39 of MCI. Most patients with dementia (76.4%) and MCI (74.3%) had at least a BAAD score = 1. Median (IQI) BAAD score was higher in VD, 4 (1.0-6.5). In the regression analysis, BAAD score was associated with MMSE, controlling for covariates. Conclusions: In our sample, the anticholinergic burden was high and correlated with dementia severity.
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Guo, Wenjun, Seungwook Kim, Sangjun Son, Changhyung Hong, Hyunjung Shin, and Kyungwon Lee. "Data-driven dementia diagnosis record visualization system." In VINCI '17: 10th International Symposium on Visual Information Communication and Interaction. New York, NY, USA: ACM, 2017. http://dx.doi.org/10.1145/3105971.3108445.

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Cejnek, Matous, Ivo Bukovsky, and Oldrich Vysata. "Adaptive classification of EEG for dementia diagnosis." In 2015 International Workshop on Computational Intelligence for Multimedia Understanding (IWCIM). IEEE, 2015. http://dx.doi.org/10.1109/iwcim.2015.7347075.

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Lins, A. J. C. C., M. T. C. Muniz, and C. J. A. Bastos-Filho. "Comparing Machine Learning Techniques for Dementia Diagnosis." In 2018 IEEE Latin American Conference on Computational Intelligence (LA-CCI). IEEE, 2018. http://dx.doi.org/10.1109/la-cci.2018.8625209.

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Karakostas, Tasos, Simon Hsiang, Boyd Davis, Dena Shenk, and Margaret Maclagan. "Development of a Dementia-Specific Gait Profile: A Computational Approach." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-63588.

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The rate at which elderly are being diagnosed with dementia has accelerated over the recent years and it is alarming [1]. They are three times more likely to fall and over three times more likely to have severe injury compared to cognitively unimpaired elderly [2]. Consequently, recently there is an interest in the identification of biomarkers that can contribute towards, or establish, early detection and diagnosis of dementia.
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Almeida, Mariana, Paulo Caramelli, Maira Barbosa, Ana Paula Santos, and Karolina Carmona. "ALCOHOL CONSUMPTION AND COGNITIVE AND FUNCTIONAL PERFORMANCE IN OLDER ADULTS AGED 75+ YEARS: THE PIETÀ STUDY." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda034.

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Introduction: The relationship between alcohol and cognition is complex. Objective: To investigate the association of alcohol consumption with cognitive impairment, functionality, psychiatric and neurological diagnoses. Methods: Cross-sectional population-based study. 602 subjects 75+ years were categorized according to the number of drinks consumed per week: 0 (abstainers); 0.1 to 7 (light); 7.1 to 14 (moderate); > 14 (heavy). Cognitive diagnoses were established: dementia, cognitive impairment no dementia (CIND) and without cognitive impairment. Results: On multivariate analysis there was no association between cognitive profile and current or previous alcohol consumption. When previous alcohol consumption was treated as dichotomous variable, no association emerged with cognitive profile (p=0.109). As for current habit of alcohol intake treated as dichotomous variable, the absence of alcohol consumption was associated with dementia (OR=2.34; 95%CI: 1.39- 3.90), stroke (p=0.014), current major depression (p=0.013), parkinsonism (p=0.041) and worse functionality (p=0.001). Cachaça consumption was associated with dementia (OR=2.52; 95%CI: 1.25-5.04). Conclusion: Absence of current alcohol consumption was associated with diagnosis of dementia, stroke, major depression, parkinsonism and worse functionality. On the other hand, intake of cachaça was associated with dementia.
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Reports on the topic "Dementia – Diagnosis"

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Fink, Howard A., Laura S. Hemmy, Eric J. Linskens, Pombie C. Silverman, Roderick MacDonald, J. Riley McCarten, Kristine M. C. Talley, et al. Diagnosis and Treatment of Clinical Alzheimer's-Type Dementia. Agency for Healthcare Research and Quality (AHRQ), April 2020. http://dx.doi.org/10.23970/ahrqepccer223.

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Mehegan, Laura, and Chuck Rainville. 2021 AARP Survey on the Perceptions Related to a Dementia Diagnosis: Adults Ages 40+. Washington, DC: AARP Research, June 2021. http://dx.doi.org/10.26419/res.00471.001.

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Mehegan, Laura, and Chuck Rainville. 2021 AARP Survey on the Perceptions Related to a Dementia Diagnosis: Attitudes Among Healthcare Providers. Washington, DC: AARP Research, June 2021. http://dx.doi.org/10.26419/res.00471.002.

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Mehegan, Laura, and Chuck Rainville. Attitudes Surrounding a Dementia Diagnosis Among Hispanic/Latino Adults Age 40 and Older — Fact Sheet. Washington, DC: AARP Research, August 2021. http://dx.doi.org/10.26419/res.00471.004.

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Mehegan, Laura, and Chuck Rainville. Attitudes Surrounding a Dementia Diagnosis Among African American/Black Adults Age 40 and Older — Fact Sheet. Washington, DC: AARP Research, August 2021. http://dx.doi.org/10.26419/res.00471.005.

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Mehegan, Laura, and Chuck Rainville. 2021 AARP Survey on the Perceptions Related to a Dementia Diagnosis: Adults Age 40-Plus Annotated Questionnaire. Washington, DC: AARP Research, August 2021. http://dx.doi.org/10.26419/res.00471.006.

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Mehegan, Laura, and Chuck Rainville. 2021 AARP Survey on the Perceptions Related to a Dementia Diagnosis (Attitudes Among Healthcare Providers): Annotated Questionnaire. Washington, DC: AARP Research, August 2021. http://dx.doi.org/10.26419/res.00471.003.

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Ataie, Jutta. "Who Would Have Thought, With a Diagnosis Like This, I Would be Happy?": Portraits of Perceived Strengths and Resources in Early-Stage Dementia. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.1107.

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Cheng, Yu-Chung N. Development and Testing of Iron Based Phantoms as Standards for the Diagnosis of Microbleeds and Oxygen Saturation with Applications in Dementia, Stroke, and Traumatic Brain Injury. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada601806.

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Zhang, Chen qi, kexin Zheng, Lingqi Sun, and Hongbin Sun. Effects of magnesium valproate adjuvant therapy on patients with dementia: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2021. http://dx.doi.org/10.37766/inplasy2021.11.0038.

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Review question / Objective: To evaluate the efficacy of magnesium valproate(VPM) in the adjuvant treatment of patients with dementia(PwD). Participant or population: Adults with dementia (as diagnosed by a clinician, or using any recognized diagnostic criteria) will be included. Information sources: MEDLINE via PubMed, Cochrane Library, EBSCO, Embase, China National Knowledge(CNKI) and Wan fang databases.
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