Dissertations / Theses on the topic 'DEM of Difference'
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Ryherd, Julia Kay. "QUANTIFYING THE RATES AND SPATIAL DISTRIBUTION OF RECENT SEDIMENTATION WITHIN THE HYDROLOGICALLY CONNECTED FLOODPLAINS OF THE MIDDLE MISSISSIPPI RIVER, USA, USING DIGITAL ELEVATION MODELS AND DENDROGEOMORPHOLOGY." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/theses/2189.
Full textRosenberger, Elke. "Asymptotic spectral analysis and tunnelling for a class of difference operators." Phd thesis, [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=98050368X.
Full textRekowsky, Isabel Cristiane. "Variações de área das geleiras da Colômbia e da Venezuela entre 1985 e 2015, com dados de sensoriamento remoto." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/149546.
Full textIn this study, glaciers located in Colombia and Venezuela (inner tropics) were mapped between 1985-2015. The area of these glaciers was measured and the variations that occurred in each glacier were compared to identify whether the glacier was growing or shrinking. The minimum elevation of the glaciers fronts and the aspect of the glaciers were analyzed. The glaciers areas ware obtained by the use of Landsat images, TM, ETM+ and OLI sensors. The Normalized Difference Snow Index (NDSI) was applied to the selected images, in which two bands were used, where the ice mass has opposite (or very different) spectral behavior: bands 2 and 5 from sensors TM and ETM+, and bands 3 and 6 from sensors OLI. The elevation and the aspect data of the glaciers were obtained from SRTM (Shuttle Radar Topography Mission – v03) Digital Elevation Model. In 1985/1986, the sum of the areas of the seven studied glaciers corresponded to 92.84 km², while in the last year analyzed (2015/2016), this value shrank to 36.97 km². The area shrinkage occurred in all the glaciers that were mapped, with annual decline rates ranging from 2.49%/year to 8.46%/year. It is also possible to observe a decrease of the ice covered in all aspects considered, as well as an elevation in all glaciers fronts. In addition to the area loss occurred at lower altitudes, where the ablation rate is higher than in higher altitudes, shrinkage in some mountain tops was also present, which is evidenced by the occurrence of lower maximum elevations in the final years of the study, when compared with the initial years. Considering that part of the Colombian’s glaciers are located on active volcanoes, these areas are influenced by external and internal factors, and the occurrence of volcanic eruption and/or earthquake can cause sharp mass losses.
PODESTA', ARIANNA. "L’IMPATTO DEI MEGA-EVENTI SUL WELFARE DI UNA CITTÀ: UN'ANALISI DEL MERCATO IMMOBILIARE APPLICATA AL CASO DELE OLIMPIADI DI TORINO." Doctoral thesis, Università Cattolica del Sacro Cuore, 2014. http://hdl.handle.net/10280/3678.
Full textIn a context of increasing globalisation and competition between cities, hosting mega-events is an opportunity to accelerate economic, infrastructural, social and urban transformation. This dissertation aims at analysing if Turin was able to transform the hosting of the 2006 Winter Olympic Games in a long-lasting legacy for the city, separating the effect of the Olympics per se from the ones of public investments and visibility. In doing so, the first chapter highlights the importance of event hosting for local economies and provides a general framework of analysis, discussing the choice of housing prices dynamics to evaluate the impact of mega events with respect to other methods used in literature, as well as the one of difference-in-differences technique. Finally, the theoretical background of the empirical analysis that follows in the subsequent chapters is presented along with the choice of the case of Turin’s Olympics. The second paper aims at disentangling the differential effect of local public investments (introducing a new direct measure of them) on city appeal, distinguished from that of hosting the Olympics per se. The third paper extends the empirical analysis introducing the role of international visibility in shaping the legacy of Turin Olympics. In doing so, an innovative index of visibility is constructed using data from the Google Trend Tool.
PODESTA', ARIANNA. "L’IMPATTO DEI MEGA-EVENTI SUL WELFARE DI UNA CITTÀ: UN'ANALISI DEL MERCATO IMMOBILIARE APPLICATA AL CASO DELE OLIMPIADI DI TORINO." Doctoral thesis, Università Cattolica del Sacro Cuore, 2014. http://hdl.handle.net/10280/3678.
Full textIn a context of increasing globalisation and competition between cities, hosting mega-events is an opportunity to accelerate economic, infrastructural, social and urban transformation. This dissertation aims at analysing if Turin was able to transform the hosting of the 2006 Winter Olympic Games in a long-lasting legacy for the city, separating the effect of the Olympics per se from the ones of public investments and visibility. In doing so, the first chapter highlights the importance of event hosting for local economies and provides a general framework of analysis, discussing the choice of housing prices dynamics to evaluate the impact of mega events with respect to other methods used in literature, as well as the one of difference-in-differences technique. Finally, the theoretical background of the empirical analysis that follows in the subsequent chapters is presented along with the choice of the case of Turin’s Olympics. The second paper aims at disentangling the differential effect of local public investments (introducing a new direct measure of them) on city appeal, distinguished from that of hosting the Olympics per se. The third paper extends the empirical analysis introducing the role of international visibility in shaping the legacy of Turin Olympics. In doing so, an innovative index of visibility is constructed using data from the Google Trend Tool.
Lundberg, Tilda, and Hanne Enoksson. "Flygskatt - Kjempebra eller kan det va? : En kvantitativ studie om hur individers konsumtion av flygresor påverkas av den norska flygskatten." Thesis, Uppsala universitet, Nationalekonomiska institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-387888.
Full textBalaguer, Puig Matilde. "Análisis empírico de soluciones fotogramétricas en estudios de erosión hídrica en laboratorio." Doctoral thesis, Universitat Politècnica de València, 2015. http://hdl.handle.net/10251/58989.
Full text[ES] La erosión hídrica del suelo es hoy un problema económico y ecológico en todo el mundo. La investigación actual de los procesos que intervienen en la erosión requiere información detallada sobre la topografía de la superficie del suelo con resolución y precisión adecuadas a la escala de trabajo. Una parte de los estudios que se realizan para la modelización y cuantificación de los procesos erosivos se llevan a cabo en laboratorio, a escalas de detalle (milimétricas), y necesitan métodos capaces de proporcionar mediciones precisas de la superficie, de una manera eficiente. Los experimentos realizados en laboratorio para la medición de la erosión hídrica se basan en el uso de simuladores de lluvia sobre parcelas de suelo de reducidas dimensiones. La rugosidad o microrrelieve del suelo influye considerablemente en el reparto de agua de lluvia entre infiltración y escorrentía, y es un parámetro importante para la modelización de procesos erosivos. La medición precisa del relieve de la parcela antes y después de la simulación de la lluvia permite estimar la erosión a partir de las diferencias de volumen. Así, en los últimos años se ha producido una creciente demanda de datos topográficos de precisión en el ámbito de las ciencias geomorfológicas. La representación de la superficie del suelo se realiza a través de Modelos Digitales de Elevaciones (MDE), generados a partir de datos altimétricos masivos, adquiridos mediante escáneres láser o por técnicas fotogramétricas basadas en imágenes. La obtención de estos datos se ha realizado mediante técnicas fotogramétricas clásicas (entre otras) hasta hace poco; sin embargo, no es una tarea trivial, y además para conseguir las precisiones necesarias se ha de trabajar con una metodología rigurosa que tenga en cuenta todas las fuentes de error en el proceso. Los avances experimentados en fotogrametría digital y otros ámbitos relacionados, como el procesamiento de imágenes y la visión por computador, han proporcionado nuevas herramientas software disponibles con gran potencial de aplicación en muchas y variadas disciplinas, entre ellas la geomorfología y el estudio de la erosión. El método Structure from Motion (SfM) obtiene de forma automática un modelo 3D de un objeto a partir de múltiples imágenes convergentes empleando métodos automáticos de registro imagen a imagen y algoritmos de correspondencia de imágenes, lo que permite un alto nivel de automatización y una mayor facilidad de uso, con un coste muy bajo. En esta tesis se pretende establecer una metodología para la obtención de MDE de una zona experimental en laboratorio tras sucesivos episodios de simulación de lluvia mediante técnicas fotogramétricas basadas en SfM. A partir de los MDE obtenidos se realizará una estimación de la erosión aplicando técnicas de diferencias de MDE (DoD), contrastando estas estimaciones con los resultados de los sedimentos arrastrados por la escorrentía y la infiltración para validar el método. Los resultados han demostrado la idoneidad de esta técnica en los estudios de erosión en laboratorio.
[CAT] L'erosió hídrica del sòl és actualment un problema econòmic i ecològic en tot el món. La investigació actual dels processos que intervenen en l'erosió requereix informació detallada sobre la topografia de la superfície del sòl amb resolució i precisió adequades a l'escala de treball. Una part dels estudis que es realitzen per a la modelització i quantificació dels processos erosius es duen a terme en laboratori, a escales de detall (mil·limètriques) , i necessiten mètodes capaços de proporcionar mesuraments precisos de la superfície, d'una manera eficient. Els experiments realitzats en laboratori per al mesurament de l'erosió hídrica es basen en l'ús de simuladors de pluja sobre parcel·les de sòl de reduïdes dimensions. La rugositat o microrrelleu del sòl influeix considerablement en el repartiment d'aigua de pluja entre infiltració i escolament, i és un paràmetre important per a la modelització de processos erosius. La medició precisa del relleu de la parcel·la abans i després de la simulació de la pluja permet estimar l'erosió a partir de les diferències de volum. Així, en els últims anys s'ha produït una creixent demanda de dades topogràfiques de precisió en l'àmbit de les ciències geomorfològiques. La representació de la superfície del sòl es realitza a través de Models Digitals d'Elevacions (MDE) , generats a partir de dades altimètriques massives, adquirides per mitjà d'escàners làser o per tècniques fotogramètriques basades en imatges. La obtenció d'estes dades s'ha realitzat amb tècniques fotogramètriques clàssiques (entre altres) fins fa poc; no obstant això, no és una tasca trivial, i a més per a aconseguir les precisions necessàries s'ha de treballar amb una metodologia rigorosa que tinga en compte totes les fonts d'error en el procés. Els avanços experimentats en fotogrametria digital i altres àmbits relacionats, com el processament d'imatges i la visió per computador, han proporcionat noves ferramentes disponibles amb gran potencial d'aplicació en moltes i variades disciplines, entre elles la geomorfologia i l'estudi de l'erosió. El mètode Structure from Motion (SfM) obté de forma automàtica un model 3D d'un objecte a partir de múltiples imatges convergents emprant mètodes automàtics de registre imatge a imatge i algoritmes de correspondència d'imatges, la qual cosa permet un alt nivell d'automatització i una major facilitat d'ús, amb un cost molt baix. En esta tesi es pretén establir una metodologia per a l'obtenció de MDE d'una zona experimental en laboratori després de successius episodis de simulació de pluja per mitjà de tècniques fotogramètriques basades en SfM. A partir dels MDE obtinguts es realitzarà una estimació de l'erosió aplicant tècniques de diferències de MDE (DoD) , contrastant estes estimacions amb els resultats dels sediments arrossegats per l'escolament i la infiltració per a validar el mètode. Els resultats han demostrat la idoneïtat d'esta tècnica en els estudis d'erosió en laboratori.
Balaguer Puig, M. (2015). Análisis empírico de soluciones fotogramétricas en estudios de erosión hídrica en laboratorio [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/58989
TESIS
Stenbeck, Kelly, and Daniel Törnqvist. "EXPANSION AV KOLLEKTIVTRAFIKEN – ÄR DET VÄRT PENGARNA? : En studie av bostadspriser och den planlagda tunnelbanan i Stockholm." Thesis, Uppsala universitet, Nationalekonomiska institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-387788.
Full textEmery, Russell N. "Refining and Expanding the Feature Stamping Process." Diss., CLICK HERE for online access, 2005. http://contentdm.lib.byu.edu/ETD/image/etd1004.pdf.
Full textGAZZAROLI, DILETTA. "Culture della differenza e diversity management nelle organizzazioni: una sfida già raccolta?" Doctoral thesis, Università Cattolica del Sacro Cuore, 2017. http://hdl.handle.net/10280/32573.
Full textIn the field of organizational psychology, Diversity Management is a topic of growing interest. Studies on Diversity Management have been led by the gradual awareness that for organizations, fostering diversity not only helps to ensure the satisfaction and performance of the individual workers, but also offers benefits in terms of business and recognition from external stakeholders and social context. Podsiadlowski et al. (2012) identified five different ways organizations approach diversity – Reinforcing Homogeneity, Color-Blind, Fairness, Access, Integration – that can be seen on a continuum from defensive, to reactive, to proactive attitude. Aim of this work is taking a picture of the organisational cultures of difference in the Italian context in order to understand "the state of the art". Moreover, this work aims to understand: if and what kind of interactions the organisational cultures of difference can have with other organizational life factors and what kind of impact the organisational cultures of difference can have on organizational creativity and individual well-being. In order to offer a contribution to the validation of two tools not yet particularly widespread in terms of use in the Italian context we also tested the psychometric properties of: the Cultural Intelligence Scale and the Diversity Perspective Questionnaire.
GAZZAROLI, DILETTA. "Culture della differenza e diversity management nelle organizzazioni: una sfida già raccolta?" Doctoral thesis, Università Cattolica del Sacro Cuore, 2017. http://hdl.handle.net/10280/32573.
Full textIn the field of organizational psychology, Diversity Management is a topic of growing interest. Studies on Diversity Management have been led by the gradual awareness that for organizations, fostering diversity not only helps to ensure the satisfaction and performance of the individual workers, but also offers benefits in terms of business and recognition from external stakeholders and social context. Podsiadlowski et al. (2012) identified five different ways organizations approach diversity – Reinforcing Homogeneity, Color-Blind, Fairness, Access, Integration – that can be seen on a continuum from defensive, to reactive, to proactive attitude. Aim of this work is taking a picture of the organisational cultures of difference in the Italian context in order to understand "the state of the art". Moreover, this work aims to understand: if and what kind of interactions the organisational cultures of difference can have with other organizational life factors and what kind of impact the organisational cultures of difference can have on organizational creativity and individual well-being. In order to offer a contribution to the validation of two tools not yet particularly widespread in terms of use in the Italian context we also tested the psychometric properties of: the Cultural Intelligence Scale and the Diversity Perspective Questionnaire.
Fraisse, Geneviève. "La difference des sexes recherches sur une forme de la connaissance." Paris, EHESS, 1997. http://www.theses.fr/1997EHES0110.
Full textThe notion of sexual difference does not belong to an already constituted field of research. In philosophy, it is not recognized as a philosophical object. In the last twenty years, my research's main objective has been the production of the epistemological conditions necessary for the constitution of such a field. Through the history of modern and contemporary feminist thought i have tried to answer questions of definition: the definitions of women's reason, of modern citizenship, of political emancipation. Dealing with the history of thought requires a genealogical reading of modernity: my purpose was to understand how women have been excluded from the res publica in the wake of the french revolution, and then how they have been at the same time included and discriminated against. My reading of modernity clearly shows how difficult it is to give a content to the notion of "equality" of the sexes. My analysis of modernity also allows and calls for an attentive reading of the major philosophers. Such a reading shows how the difference of the sexes intervenes in the very process of philosophical thought: the "women's question" raises interesting stakes for philosophers, while the difference of the sexes appears as an important operator in the dynamic process of the end of metaphysics. Thinking through the difference of the sexes thus becomes a philosophical objective. Western philosophical tradition both shows how eros and love have been used as a way to think about the sexes and, consequently, how philosophy has envisaged the place of sexual difference in its own history. In fact, the difference of the sexes intervenes in two ways in philosophical thought: first as a primal difference through which humanity thinks about itself, and second as a means of exchange within thought itself. For philosophers, sexual difference is thus not an object of thought but rather an origin and a means through which thought is produced
Künnecke, Arndt. "Eine Hürde auf dem Weg zur EU-Mitgliedschaft? der unterschiedliche Minderheitenbegriff der EU und der Türkei." Hamburg Kovač, 2007. http://www.verlagdrkovac.de/978-3-8300-3123-9.htm.
Full textNilsson, Sara. "Leder den ökade alkoholkonsumtionen till fler trafikolyckor?" Thesis, Uppsala University, Department of Economics, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5998.
Full textI denna studie undersöks huruvida den ökade alkoholkonsumtionen utgör ett problem för att
uppnå Nollvisionen. Genom att använda experimentet med lördagsöppna Systembolag
estimeras effekterna av en ökning i alkoholkonsumtion på trafikolyckor. Försöket med de
lördagsöppna Systembolagsbutikerna i sex län ledde till en ökad alkoholkonsumtion med 3,7
procent. En Difference-in-Difference metod används för att jämföra effekterna av denna
ökning på trafikolyckor i de sex försökslän med utvecklingen i en kontrollgrupp. Resultaten
visar att konsumtionsökningen har ökat det totala antalet trafikolyckor i försökslänen med
8,5±2,6 procent i jämförelse med kontrollgruppen. Effekterna visar sig även skilja sig åt
mellan olika olycksutfall; större effekter uppvisades för de svårare olycksutfallskategorierna.
Den starkaste effekten uppvisades för kategorin svårt skadade som ökade med hela 26,4±5,6
procent. Resultaten tyder alltså på att den ökade alkoholkonsumtionen utgör ett problem för
att uppnå Nollvisionen.
Lindgren, Emma, and Olivia Wright. "Sätter flygskatten några spår på vårt resande? : En studie om den svenska flygskattens påverkan på det inhemska flyg- och tågresandet." Thesis, Uppsala universitet, Nationalekonomiska institutionen, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-433809.
Full textOn the 1st of April 2018, the Swedish government introduced a tax on air travel, with the intention that the airlines should bear their own climate costs and to reduce the plane’s environmental impact. The object of this study is to examine how the Swedish aviation tax has affected the amount of total internal flight and train journeys in Sweden. The method used is the quasi-experimental method difference-in-differences, where Sweden is used as the treatment group and Finland as the control group. The period of analysis is from January 2013 to December 2019. The result of this study shows that the increase in the amount of train passengers is considerably larger than the decrease in the amount of flight passengers, which depicts the stronger upgoing trend in train journeys in Sweden. Therefore, it is not possible to see the effect of the aviation tax on the internal train journeys in this study. Yet it is feasible to see a diminishment in the amount of internal flight journeys by 53 000 journeys a month in Sweden. This result is statistically significant on a level of five percent and demonstrates that the aviation tax has had an effect on the amount of internal flight journeys.
CAVIOLA, GIADA. "Impatto dell’ambiente materno precoce e del sesso sul comportamento e metabolismo in due modelli murini KO." Doctoral thesis, Università degli studi di Modena e Reggio Emilia, 2020. http://hdl.handle.net/11380/1200998.
Full textInteractions between genes and environment are recognized to play a critical role in modulating the development of the organism. More in details early maternal environment seems to be a key factor in shaping neuro-behavioral development; the mother-infant bond is the strongest and more common social relationship in mammal species and phylogenetically highly conserved. Experimental evidence demonstrated that maternal behavior may act on the regulation of genetic expression; in adult life, the offspring that had received high levels of maternal cares showed lower anxiety, less ACTH and Corticosterone production, less aging effect on hyppocampus and more immune activity in response to stress. In the present experiments we investigated the interaction between early maternal environment and specific genetic background, in relation to sex on metabolism and behaviour. We examined two different genetically modified mice models; the first one is a mouse model characterized by a conditional knock-out of the Y1 receptor in the excitatory neurons of the forebrain; the second one is a knockin mouse model of selective loss of the VGF peptide TLQP-21. To test the hypothesis that the effects of gene deletion may vary in relation to early maternal environment, in the first experiment male and female, Npy Ko and control mice were fostered at birth to dams that displayed high or low levels of maternal care (CD1 swiss, FVB – C57/Bl6, Balb/c respectively). As adults mice were tested for emotional, aggressive and social behavior and metabolic changes in response to standard or high fat diets. In the second experiment we performed a detailed analysis of the effect of early maternal environment on control animals of the Npy Y1r KO model. In the third experiment we observed maternal behavior and reproductive success in ΔTLQP-21 heterozygotes or homozygotes breeders and characterized their offspring by an analysis of emotional and depression-like behaviors in adult males and females. Overall the results of the first study showed that males, but not females, had an increase in axiety-like behavior and weighted less than their controls, but only when reared by foster mothers displaying high levels of maternal care. In the second experiment, we demonstrated that early maternal environment affected offspring development but its impact can not be ascribed entirely to the variation in maternal cares; in fact also maternal milk quality/quantity and nutritional factors could be important variables influencing behavior and metabolism in adult’s life. Lastly, results in the third study indicated that the mutation in TLQP21 gene influence maternal behavior, with mutant or heterozygotes breeders displaying lower amount of maternal care (defined by the time spent in the arched back position) when compared with wild type mice. Such a difference affected the offspring subsequent behavioral phenotype as adults, particularly emotional behaviour and sex related differences . Further study will be necessary to investigate the role of nutrition and maternal milk in metabolic and behavioural development of offspring in both NPY KO and WT animals, and to better understand the role of early maternal environment in ΔTLQP-21 mouse. The present findings, however, highlight the importance to take into consideration and control for the complex interaction between genes, early maternal environment and sex-related effects when working with GM mouse models to uncover specific gene functions.
Voss, Heinz-Jürgen. "Making Sex Revisited : Dekonstruktion des Geschlechts aus biologisch-medizinischer Perspektive /." Bielefeld : Transcript, 2010. http://deposit.d-nb.de/cgi-bin/dokserv?id=3391266&prov=M&dok_var=1&dok_ext=htm.
Full textDea, John Edwin III. "Differences between doctoral level nurse practitioner programs and master level nurse practitioner programs as reflected in the terminal objectives and curricular patterns." Thesis, Montana State University, 2008. http://etd.lib.montana.edu/etd/2008/dea/DeaJ0508.pdf.
Full textAhrlind, Kevin, and Dennis Olsson. "Sveriges flygskatt : En empirisk studie av den svenska flygskattens effekt påantalet resenärer." Thesis, Stockholms universitet, Nationalekonomiska institutionen, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-190494.
Full textPAGAN, ELEONORA. "Sex-based differences in cancer immunotherapy efficacy." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/306599.
Full textIn the last decade lots of research efforts were put in the field of immunotherapy, a relatively new class of treatments that boost the body’s natural defenses to fight against cancer. In medical research, despite growing evidence that sex (i.e., differences between men and women at biological level) might be a disease treatment modifier, sex-based differences in the presentation, progression, adverse events as well as in the prophylactic or therapeutic treatment of diseases were rarely analyzed and reported. Only in 2018, Conforti and colleagues found, for the first time, that considering patients affected by several types of advanced cancers, and treated with immune checkpoint inhibitors as monotherapy or as a combination therapy, males derive larger effect on OS then females do. The overall aim of this doctoral thesis was to extend previous (limited) knowledge on sex-based differences in cancer immunotherapy efficacy and to further explore mechanisms at molecular level that regulate anticancer immune response in men and women. First, we investigated whether, and confirmed that, women with advanced lung cancer derive larger benefit than men from the combination of chemotherapy to an anti-PD-1/PD-L1. We found also an interaction between patients’ sex and the efficacy in OS of two therapeutic strategies (anti-PD-1/PD-L1 alone or in combination with chemotherapy compared to standard chemotherapy) with opposite direction of the effect in men and women: men derive larger benefit than women with an anti-PD-1 treatment alone, while women have better survival with anti-PD-1/PD-L1 plus chemotherapy. Then we deeply studied the sex-based dimorphism of the response to lung cancer immunotherapy, conjecturing that the heterogeneity of response to different immunotherapeutic strategies might be due to differences in the molecular mechanisms that drive anticancer immune response in men and women. We observed a less efficient tumor recognition and infiltration by immune system in men compared to women. In particular, in men, we found a lower abundance of a number of immune cell types in the tumor microenvironment (TME), a significantly higher T-cell exclusion score, a smaller T-cell receptors repertoire diversity and a lower amount of ubiquitous expanded T-cell receptors. We found that such poorer immune infiltration of tumors in men may depend on a less efficient tumor neoantigens presentation to the immune-system, due to lower expression levels of human leukocyte antigen (HLA) class I and II molecules, higher frequency of HLA type I loss of heterozygosity and/or alterations in other component of the antigen presentation machinery. We also showed that, among the molecular pathways and biological processes most significantly enriched in the TME of women, there were many directly related to the anticancer immune response. Contrary, none of the gene sets found significantly enriched in tumors arising in men were directly related to anticancer immune responses. Moreover, we provided a clear example of the potential clinical implications of our findings, showing significant differences in the association between tumor mutational burden and survival benefit observed in men and women treated with anti-PD-1/PD-L1 antibodies. We implemented several statistical methods to answer the different questions depending on the aim of each study. We used meta-analyses to combine results from several studies and to produce estimates of the overall sex-effect of interest. We used cox proportional hazard regression model to analyze survival data and, as a mean to investigate departures from linearity, restricted cubic splines were applied to model the relationship between continuous covariates and the survival outcome of interest. Several bioinformatic tools were used to process the data. Moreover, we implemented the Gene Set Enrichment Analysis methodology in the statistical software SAS with an extension to meta-analysis.
Doberauer, Johannes. "Regionale Differenzen der Spongiosastruktur in den Brustwirbelkörpern 2 und 8." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-140549.
Full textIannuzzi, Francesco Eugenio. "Assemblare le differenze. Il lavoro tra frammentazioni, migrazioni e resistenze nell'industria alberghiera veneziana." Doctoral thesis, Università degli studi di Padova, 2019. http://hdl.handle.net/11577/3424952.
Full textInspired by the growth of the service sector over the past decades, the issue of the hospitality labour has gradually gained the attention of scholars from different disciplines. Nowadays, the hospitality industry is regarded as the quintessence of labour studies, both by virtue of its ability to assemble some of the main trends of the contemporary labour and because every single hotel is an ideal place to show the production and reproduction of occupational hierarchies and social stratifications. A large part of the literature has hitherto addressed some of the challenges posed by the hotel labour through two macro analytical approaches. The first, which is close to geographers, focuses on the spatiotemporal dynamics of the hospitality and on the relationship between multi-scalar production, the processes of vertical disintegration – included outsourcing – and the contractual fragmentation of the labour force. The second, more interested in grasping labour transformations, deals with the dynamics of interaction, the production of social differences in the workplaces and the labour market segmentation. Based on an empirical research carried out in the Venetian hospitality industry, the purpose of this thesis is to show how the intersection of social identities of workers shapes the organization of productive relationships, thus affecting the division of labour. More to the point, the aim of the research is to answer to the following questions: a) whether and how does the social differentiation of the workforce interact with the segmentation of production and labour market and what are the consequences of this relationship on the labour process organization? What affects the social and technical division of labour of the hospitality industry? What are the effects that the fragmentation generates on everyday social relations among workers? What are the forms of resistance and agency that workers - individually or collectively- put in place as inside as outside the workplace to challenge the experiences of inequality and to reassemble the social fractures? In this work, it is argued that to capture the effects of social and occupational hierarchization marking the everyday experiences of hotel workers, it is necessary to pay attention to the ways in which the technical division of labour overlaps with the social division of workers. The intersection between production and occupational fragmentation, labour market segmentation and social stratification of workers allow us to explore both the forms of multiple fragmentations which characterize the hotel labour and the reproduction of the experiences of inequality among workers. The joint analysis of the fragmentation process which characterizes the hotel labour is based on the empirical and theoretical proposal to consider every single hotel as able to reproduce, on a local scale, the specific functioning and consequences of the global production networks. As a matter of fact, a hotel, while being prevented to delocalize, is able to use locally some of the economic, political and social condition of exploitation (that usually other firms shall ensure with offshoring process), to disarticulate the production process - via outsourcing - and to segment the labour force without spatial dispersion of activities. In doing so, it produces some of the phenomena which are normally traceable across and along the global production networks, including the multiplication and the subsequent connection of forms and regimes of labour and the assemblage of social vicissitudes and heterogeneities. At the same time, social relations of hotel workers are deeply affected by the reproduction of social borders and by occupational, wage and power hierarchies. While working together in a relatively limited space, indeed, those workers recognize themselves in a different social and productive fate. The research has been conducted by using qualitative methods especially in-depth interviews with workers, unionist and managers of the Venetian hospitality industry during the years 2014 -2018
Straub, H. J. Robert. "Überprüfung der Validität eines funktionell kurzen Beines auf der Seite der Ilium-Subluxation." Master's thesis, Dresden International University, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-236518.
Full textDorr, Mareike. "Gemeinsamkeiten und Differenzen in den theoretischen Grundlagen der Neoklassik und der Neuen Institutionenökonomik /." Duisburg : WiKu-Verl, 2008. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016464530&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Full textDorr, Mareike. "Gemeinsamkeiten und Differenzen in den theoretischen Grundlagen der Neoklassik und der Neuen Institutionenökonomik." Duisburg Köln WiKu, 2007. http://d-nb.info/987695851/04.
Full textJaramillo, Gutiérrez Ainhoa. "Gender differences in strategic and risky environments." Doctoral thesis, Universitat Jaume I, 2007. http://hdl.handle.net/10803/10362.
Full textBesides, we study gender differences in individual decision making under uncertainty using the lottery panel test introduced in Sabater-Grande and Georgantzís (2002). Regarding risk aversion, our results confirm that female subjects are more risk averse than males. Regarding sensitivity to risk, female subjects are less attracted than men by the linear risk premia used in the design of the four panels.
Our evidence suggests that gender and risk-related effects in ultimatum bargaining can and should be disentangled as two separate idiosyncratic dimensions. Specifically, although we confirm the broadly accepted result that females are more risk averse than males, we find that offers made by females are lower than those posted by male subjects. In fact, the gender effect becomes stronger once risk attitudes are accounted for. Gender effects are found to depend also on cultural differences. In sessions with Greek and Spanish subjects we obtain gender differences of the same sign and similar sizes, whereas British females' behavior differs from that of males only in the case of employee subjects and in the opposite direction to the gender effect reported on subjects from the two Mediterranean countries.
Spring, Ted. "Uncertainty comparison of Digital Elevation Models derived from different image file formats." Thesis, Högskolan i Gävle, Avdelningen för Industriell utveckling, IT och Samhällsbyggnad, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-17193.
Full textKrautz, Martin. "Bestimmung von relevanten Veränderungen des Mundgesundheitszustandes." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-64218.
Full textEriksson, Joseph. "Finanskrisens effekt på utbildning : En paneldatastudie på kommunnivå över sambandet mellan finanskrisensrealekonomiska konsekvenser på Sveriges ekonomi och den potentiellainverkan på de nationella proven." Thesis, Uppsala universitet, Nationalekonomiska institutionen, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-430498.
Full textBlot, Christian. "Immunotoxicité des molécules médicamenteuses : mécanismes impliqués dans les différences inter-espèces." Paris 11, 1994. http://www.theses.fr/1994PA114844.
Full textOnana, Marie Biloa. "Der Sklavenaufstand von Haiti ethnische Differenz und Humanitätsideale in der Literatur des 19. Jahrhunderts." Köln Weimar Wien Böhlau, 2008. http://d-nb.info/994074506/04.
Full textNESSI, CECILIA. "Existing in/difference. Lesbian perspectives on urban encounters." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2019. http://hdl.handle.net/10281/258898.
Full textThis work aims at expanding the debate about diversity, difference and urban minorities in Western European cities, looking from a queer and intersectional perspective. This interdisciplinary study explores the meaning of encounter and the spatial dimension of lesbian identifications, a subaltern location in terms of gender and sexuality but dominant from a homonationalist frame. My aim was to explore the everyday relationships with the city from the perspective of lesbians, a largely understudied subject within urban literature outside the U.K. or the U.S.A. The research is based on participant observation that I conducted between 2015 and 2018 in Milan and in Brussels, and 45 interviews: 29 with participants and 16 with key informants. I adopted qualitative methodologies and a grounded approach based on abductive reasoning and constant comparison. The participants were selected on the basis of their sexual orientation and their relationship with the city (being a migrant to the city). I retrace the emergence of lesbian subjectivities in Milan and Brussels as a result of a double exclusion (both within gay and feminist movements). Challenging the majoritarian/minoritarian opposition, the research highlights that differences are reproduced within the definition of the lesbian category itself. In particular, I look at how gender, race, and class weave together and impact the negotiations with the urban space, with lesbian spaces and with the category of lesbian itself. The results show that the participants identify, counteridentify, and disidentify with the category of lesbian in many ambiguous ways. Ultimately, the conflicts for accessing certain spaces of comfort (both physical and relational) render intelligible the other lines of privilege: white, gender-conforming, middle-class. These modalities of assimilation, resistance, and disidentification, in fact, are reflected in their spatial experiences of the city through what I call shrinking maps as a result of avoidance and negotiation of both homo- and hetero- normativities between being just a normal client and looking for safe spaces made of people with whom I dont have to explain. By shrinking maps I mean that the possibilities of encounters are reduced by non-encounters. Reconsidering the centrality of visibility, I show how the participants sometimes move through the spaces as what I call present-absences: they are not intelligible through places and relationships scripts when they pass sometimes as man, sometimes as straight. Places, indeed, are not accessible to everybody: the materiality of difference emerges in the embodied possibilities to choose, or not, among different strategies to access spaces and identifications. Exclusionary practices are reproduced along the lines of class, race and notably nonconforming gender expressions, as in the case of butches and femmes that are perceived as excessive. The price is being excluded not only from spaces, but from lesbian existance: you cannot be a real lesbian. To sum up, in this thesis I suggest that there is no safe space: lesbian as a co-formation reproduces other exclusions through homonormative transexclusions in the case of Milan and reproducing white hegemony, particularly contested in the case of Brussels. Reconsidering the literature on encounter, this study shows that where plurality is not recognized through imaginaries, practices and performances the access to identification for certain subjectivities is erased and, along with it, so does the very possibility of encounters. An analysis in terms of co-formations might be helpful in order to recognize power dynamics beyond oppositional discourses, therefore enhancing transidentiarian solidarities and broaden the accessibility to imaginaries, relationships and spaces within the city. Keywords encounters, lesbian subjectivities, visibility, disidentifications, whiteness.
PATAT-OCHATT, ESTELA MARIA. "Regeneration de plantes a partir de protoplastes de pommier (malus xdomestica borkh. ) : etude des exigences de culture pour differents genotypes apparentes de ploidie differente." Rennes 1, 1993. http://www.theses.fr/1993REN10081.
Full textWieck, Cornelia. "Altersunterschiede in der Empathie: Multidirektional und eine Frage des Kontexts?" Doctoral thesis, Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-161298.
Full textToro, García Cristian. "Imágenes recompuestas: un análisis del narrador de The difference engine." Tesis, Universidad de Chile, 2014. http://www.repositorio.uchile.cl/handle/2250/130260.
Full textGAZANO, GERMAINE. "De l'importance des differences interindividuelles en psychophysique descriptive." Paris 7, 1990. http://www.theses.fr/1990PA077139.
Full textLAFORTUNE, STEPHANE. "Symetries et integrabilite des equations aux differences finies." Paris 7, 2000. http://www.theses.fr/2000PA077122.
Full textDabrowska, Izabela. "Polyolefin nanocomposite with different types of nanofillers." Doctoral thesis, Università degli studi di Trento, 2013. https://hdl.handle.net/11572/368488.
Full textSandführ, Thomas. "Só a antropofagia nós une: Assimilation und Differenz in der Figur des Anthropophagen." [S.l. : s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963602896.
Full textLAKKIS, ISMAIL. "Etude des differentes methodes d'imagerie radar." Nantes, 1994. http://www.theses.fr/1995NANT2031.
Full textKrepper, Eckhard, and Alexander Grahn. "Untersuchung des Verhaltens von freigesetztem Isolationsmaterial in einer Kühlmittelströmung (Kühlmittelströmung mit Feststoffpartikeln) - Modellentwicklung." Forschungszentrum Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-28331.
Full textKrepper, Eckhard, and Alexander Grahn. "Untersuchung des Verhaltens von freigesetztem Isolationsmaterial in einer Kühlmittelströmung (Kühlmittelströmung mit Feststoffpartikeln) - Modellentwicklung." Forschungszentrum Rossendorf, 2006. https://hzdr.qucosa.de/id/qucosa%3A21660.
Full textHorlacher, Stefan. "Überkreuzungsphänomene oder die Differenz in der Differenz: Nahrung, Grenzauflösung, Inkorporation und die Macht des Abjekts in The Virgin and the Gipsy." Gunter Narr Verlag, 2003. https://tud.qucosa.de/id/qucosa%3A38725.
Full textLutvica, Nina, and Rebecca Svanedal. "Kvinnor duger men våld "suger" : Ungdomars attityder till den svenska polisen." Thesis, Mälardalens högskola, Akademin för hållbar samhälls- och teknikutveckling, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-15676.
Full textCorrêa, Izabella Marques. "Gênero e currículo: um movimento de (des)construção." Universidade do Estado do Rio de Janeiro, 2013. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=7805.
Full textThe studies for the realization of this dissertation are contextualized in the epistemological field of curriculum and intend to address gender issues in the context of practice. Therefore, it was considered the prospect of Elizabeth Macedo, who understands the curriculum as a space/time border and enunciation of meanings. The research sought to emphasize that meanings of sex, gender and identities are assigned and are shown in curricular practice of professionals working in the final series of the second upper elementary school (8th and 9th ) in a private school located in the municipality of Rio de Janeiro which announces a gender-neutral position in its political - pedagogical project . The analysis aimed to show ways of construction and deconstruction of concepts that attempt to establish gender identities, believing the fragility of these fixations, considering that the identities are in a constant state of fluidity. For further reflection, beyond the dialogue with the theoretical field of curriculum, the work included the theoretical articulation and dialogue with queer studies to address issues of gender and identification processes, especially with Judith Butler and Guacira Lopes Louro. The methodology used for the elaboration of the work relied on semi - structured interviews with school personnel (teachers, director and coordinator). The statements of interviewees pointed to the difficulty of working on gender issues, but at the same time indicated the signaling cues for denaturalization of gender identities, highlighting heteronormativity and considering different ways of living sexualities. The study intended to pave the way for the understanding that gender differences are not limited to binary schemes wishing that operate with fixed dichotomous oppositions, but that they move according to the movements of the numerous contingent of differentiation processes, producing identities.
Kergoat, Marine. "Approche psychosociale et différentielle des évaluations sensorielles : intensité affective et préférences tactiles." Thesis, Paris 10, 2010. http://www.theses.fr/2010PA100200/document.
Full textThe blind sensory evaluation of consumer products often yields to heterogeneous clusters of preference. For instance, some participants have a preference for soft textiles whereas others do not have such a preference. To understand these preferences, 9 studies were conducted (N = 1128) according to a double approach: differential and functional. A differential approach systematically explored the cognitive, affective and social determinants of sensory preferences. The visual-tactile evaluation of fabrics (car seat fabrics and fabrics mainly treated with softener agents) coupled to dispositional measures highlighted the predictive value of the Affect Intensity construct (Larsen, 1984). Within a functional approach (i.e. function of attitudes; Katz, 1960; Smith, Bruner, & White, 1956) we tested the hypothesis that function of arousal regulation (Larsen, 2009) was the motivational mechanism underlying these preferences. Consumers liking soft textiles live more intensely their positive emotions and react more intensely to stimuli inducing negative emotions. On the basis of a multidimensional approach of the Affect Intensity construct (Bryant, Yarnold, & Grimm, 1996), we discussed the motivational determinants likely to be involved in consumer preference for soft textiles
Marceau, Michaël. "Impact de l'implantation du module d'enregistrement des ventes sur le secteur de la restauration au Québec." Mémoire, Université de Sherbrooke, 2015. http://hdl.handle.net/11143/8154.
Full textPAYS, PALETTE CATHERINE. "Le metabolisme de l'antipyrine comme modele d'etude de l'activite des cytochromes p-450 hepatiques : contribution a l'etude analytique des differents metabolites et application a l'exploration du metabolisme dans differentes especes animales." Paris 5, 1994. http://www.theses.fr/1994PA05W083.
Full textMenke, Christoph. "Subjektive Rechte : zur Form der Differenz." Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2009/3606/.
Full textDabrowska, Izabela. "Polyolefin nanocomposite with different types of nanofillers." Doctoral thesis, University of Trento, 2013. http://eprints-phd.biblio.unitn.it/1103/1/Izabela_Dabrowska_PhD_Thesis.pdf.
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