Books on the topic 'Degree Discipline: Clinical Research'

In the textbook the basic concepts concerning the organization and technology of information work of the student-historian are considered. It includes four sections: the first determines the place of the course's problems in the process of historical knowledge; the second tracks the principal features of facts, sources and research, which can potentially be the sphere of historical research; the third introduces the reader to the principles, conceptual apparatus, laws, methods and judgments as means of knowledge.; the fourth introduces the experience of constructing the text of the study, which sums up a certain result of the work done and allows you to " translate the process of learning a new state of relative knowledge." Meets the requirements of the Federal state educational standards of higher education of the last generation. It is intended for undergraduate students studying the discipline "Information and analytical work". It can be useful to persons preparing for admission to the master's degree in the areas of training "History" and "International relations", as well as all those interested in working with documents and other media.

The actual problems of municipal law in Russia are considered taking into account the peculiarities of master's degree training at the university, which provides for both the presence of a system of students with certain knowledge in the field of jurisprudence, including the main institutions of municipal law, and their significant focus on research work. Special attention is paid to the consideration of the main amendments and additions to the current legislation on local self-government, discussions that accompany the improvement of legislation and law enforcement practice. The electronic educational and methodological appendix to the textbook includes an approximate work program and educational and methodological materials for independent work on the study of the discipline, as well as lectures and presentations. Meets the requirements of the federal state educational standards of higher education of the latest generation. For students of educational institutions of higher education studying in the field of training 40.04.01 "Jurisprudence", as well as for graduate students, students of the system of additional professional education and teachers, all those who are interested in the problems of the development of municipal law, the theory of local self-government and the practice of state and municipal management.

Speech science has a history of over 120 years. In addition to the self-image of the discipline, this book focuses on everything that makes the subject so attractive: With its vital research and teaching subject, speaking and people talking to each other, it is both application-oriented and up-to-date. This explains the continuing high level of interest among students, research partners, and practical professional fields in education, art, media, counseling, therapy, and prevention. With study locations in Halle, Jena and Marburg, Speech Science is represented throughout Germany. As an interdisciplinary research and working subject with links to linguistics, medicine, pedagogy, psychology, politics and sociology, among others, there are also diverse collaborations in research, teaching and practice. This volume offers surprising insights into the diversity of speech science – from its history to the present to an outlook on what will be possible in the future. Susanne Voigt-Zimmermann holds a degree in speech science. After scientific, speech-educational, and clinical-therapeutic activities at the universities of Jena, Heidelberg, and Magdeburg, she has been a professor of speech science at the Department of Speech Science and Phonetics at Martin Luther University Halle-Wittenberg since 2017.

This practical book is written specifically for junior doctors by a team of highly experienced authors, as an introductory guide to clinical research. It covers all areas that a junior doctor needs to consider, including funding, study design, ethics, data analysis, disseminating findings, and furthering one's research career. It presents a balance view of clinical research and is written by authors actively involved in clinical research both at the 'coal-face' and at a more supervisory level. Research can be a difficult process and it is essential to make sure that the project is set up in the correct way in order to get verifiable results. This easy-to-read guide is available to help junior doctors develop a good study design and present evidence of a sound academic practice, which will make obtaining funding more likely and be time-efficient. Getting started early in research and developing a solid, gradual understanding of clinical research through using this approachable book will be of huge benefit to junior doctors and their discipline.

Clinicians need critical appraisal skills to weigh up the quality of the literature and to decide whether it has implications for their practice. Every belief in medicine is a construct created from the limited information available and carries a degree of uncertainty. A centralized approach to research identifies the highest priority areas of uncertainty so as to bring about the most improvement for the largest number of patients. This patient-centred model classifies studies into basic science, translational, and clinical research. Adequately powered mega-trials are required to bridge the translational gap between efficacy (does a treatment work?) and effectiveness (does a treatment work when applied in ordinary clinical practice?). There is a paucity of these in perioperative medicine.

A clinical trial is a research study that assigns people or groups to different interventions and compares the impact of these on health outcomes. This chapter examines the design and delivery of clinical trials in anaesthesia and perioperative medicine covering the issues outlined below. The features of a high-quality clinical trial include well-defined inclusion and exclusion criteria, a control group, randomization, and blinding. Outcome measures may be broadly divided into counting the number of people who experience an outcome and taking measurements on people. The outcome measures selected for a clinical trial reflect the purpose of the study and may include ‘true’ clinical measures such as major postoperative complications or surrogate measures such as the results of a biochemical test. Outcome measures may be combined in a composite outcome. Assessment of health-related quality of life using a tool such as the SF-36 questionnaire is an important aspect of many clinical trials in its own right and also informs the economic analyses that may be embedded in a trial. Determining the number for recruits needed for a clinical trial requires both clinical and statistical insight and judgement. The analysis of a clinical trial requires a similarly sophisticated approach that takes into account the objectives of the study and balances the need for appropriate subgroup analyses with the risk of false-positive results. The safe and effective management of a clinical trial requires rigorous organizational discipline and an understanding of the ethical and regulatory structures that govern clinical research.

This chapter will summarize what is considered to be the first randomized controlled trial to directly compare psychotherapeutic and psychopharmacological interventions for unipolar nonpsychotic depression. More specifically, the authors were interested in the degree to which cognitive behavioral therapy, interpersonal therapy, imipramine and a placebo condition ameliorated symptoms of depression in patients from outpatient psychiatric clinics at three academic medical centers in the United States. The chapter will discuss the design and implementation of the study before focusing on the results and their implications. The last section of the chapter will list similar studies and present a hypothetical clinical case that requires the reader to apply basic concepts learned from the study.

The Living Machines approach, which can be seen as an exemplar methodology for a wider initiative towards “convergent science,” implies and requires a transdisciplinary understanding that bridges from between science and engineering and to the social sciences, arts, and humanities. In addition, it emphasizes a mix of basic and applied approaches whilst also requiring an awareness of the societal context in which modern research and innovation activities are conducted. This chapter explores the education landscape for postgraduate programs related to the concept of Living Machines, highlighting some challenges that should be addressed and providing suggestions for future course development and policy making. The chapter also reviews some of the within-discipline and across-discipline programs that currently exist, particularly within Europe and the US, and outlines an exemplar degree program that could provide the multi-faceted training needed to pursue research and innovation in Living Machines.

The importance of trust in international relations has recently become the subject of a vibrant new agenda of research. However, as this paper shows, trust has always implicitly been at the center of international relations theory. Realism, rationalism and constructivism conceive of trust differently, with enormous substantive implications. After establishing how different understandings about the type and degree of trust that prevail in international relations help structure core debates in the discipline, this paper then turns to showing the role that trust plays in diplomacy and multilateral cooperation. Trust seems necessary for the creation of large multilateral institutions in international relations as well as value-creating diplomacy that allows for win-win outcomes.

This chapter surveys some of the newer text-analytical tools—claiming them, unabashedly, as potential instruments of algorithmic criticism. It demonstrates that the degree to which the text-analysis systems WordHoard, Text Analysis Portal for Research (TAPoR), HyperPo, and MONK (Metadata Offer New Knowledge) show the way forward, they do so largely by embracing the contingencies that once threatened the discipline of rhetoric, but that, like rhetoric, may come to form the basis for new kinds of critical acts. In an age when the computer itself has gone from being a cold arbiter of numerical facts to being a platform for social networking and self-expression, one may well wonder whether those new kinds of critical acts are in fact already implicit in the many interfaces that seek only to facilitate thought, self-expression, and community.

This book queries from three different angles what it means to speak of Homeric poetry together with the word “text.” Scholarship from outside the discipline of classical studies on the relationship between orality and textuality motivates and undergirds the project. Part I uses work in linguistic anthropology on oral texts and oral intertextuality to illuminate both the verbal and oratorical landscapes our Homeric poets fashion in their epics and what the poets were striving to do when they performed. Looking to folkloristics, Part II examines modern instances of the textualization of an oral traditional work in order to reconstruct the creation of written versions of the Homeric poems through a process that began with a poet dictating to a scribe. Combining research into scribal activity in other cultures, especially in the fields of religious studies and medieval studies, with research into performance in the field of linguistic anthropology, Part III investigates some of the earliest extant texts of the Homeric epics, the so-called wild papyri. Written texts of the Iliad and the Odyssey achieved an unprecedented degree of standardization after 150 BCE. By looking at oral texts, dictated texts, and wild texts, this book traces the intricate history of Homeric texts from the Archaic to the Hellenistic period, long before the emergence of standardized written texts. Researchers in a number of disciplines will benefit from this comparative and interdisciplinary study.

Quality assurance has its roots in industry and therefore is strongly influenced by concepts from business, hence the reference to the definition of the term ‘quality’ according to the International Standard Organization (ISO), for example. In order to better understand the various concepts of quality assurance, this chapter clarifies concepts such as ‘effectiveness’, ‘efficiency’, ‘patient-centredness’, and ‘equity’. Of major importance in clinical medicine are guidelines, standards, recommendations, and their grade of evidence. Guidelines in particular have the advantage of facilitation of the practice of evidence-based medicine in that they can provide a practically orientated summary of the relevant research literature. Other important tools for quality assurance include ‘plan–do–study–act’ (PDSA) cycles, process mapping, monitoring of outcome indicators, auditing, and peer review. Patient safety is another rather young discipline in academic medicine. Triggered by the landmark publication of To Err is Human by the US Institute of Medicine (IOM) in 1999, patient safety gained widespread attention in healthcare. Anaesthesiology as a typical safety discipline was among the first to adopt safety measures such as ‘incident reporting’ or ‘human factors training’ years before the IOM report. Safety is closely related to outcome and therefore mortality, morbidity, as well as adverse events in general have to be considered. In order to improve, safety lessons can be learned from the so-called high-reliability organizations and transferred into clinical practice.

Prekladaný vysokoškolský učebný text „Bioenergetika“ by mal slúžiť ako úvod do problematiky štúdia v oblasti bioenergetiky. Táto vedná oblast je v súčasnosti vysoko aktuálna, pretože výsledky získané bioenergetickým výskumom v uplynulých rokoch zreteľne ukazujú, že bioenergetické procesy prebiehajúce v živých systémoch neslúžia “len” na transformáciu energie, ale ovplyvňujú aj priebeh procesov ako sú apoptóza, starnutie, vznik a rozvoj mnohých ochorení (predovšetkým neurodegeneratívnych). Tieto skutočnosti jednoznačne naznačujú potrebu existencie kvalitných učebných textov, ktoré by prijateľným spôsobom umožnili študentom získať potrebné informácie a vedomosti v tejto vednej discipline. Z vyššie uvedených dôvodov sme sa rozhodli vytvoriť tieto učebné texty, ktoré sú vo forme desiatich samostatných kapitol, ktoré však na seba prirodzene a logicky nadväzujú. Jedna kapitola predstavuje v podstate jednu prednášku v rámci kurzu Bioenergetiky, ktorý je realizovaný na Prírodovedeckej fakulte Univerzity Pavla Jozefa Šafárika v Košiciach na magisterskom a doktorandskom stupni študijného programu „Biofyzika“. Zároveň tieto texty môžu poslúžiť aj pri výučbe v študijnom predmete Biochémia, ktorý je prednášaný v bakalárskych a magisterských stupňoch študijných programov “Biochémia” resp. “Biofyzika”. Dovoľujeme si vyjadriť presvedčenie, že tieto učebné texty by mohli byť istým spôsobom nápomocné aj vedeckým pracovníkom pracujúcim v oblasti výskumu týkajúcho sa problematiky transformáci energie v biologických organizmoch a fenoménoch spojených s touto transformáciou. V týchto učebných textoch sú postupne uvádzané poznatky týkajúce sa základných konceptov bioenergetiky, mechanizmov procesov ako sú glykolýza a Krebsov cyklus (okrem podrobného a uceleného popis týchto procesov je tu uvedený aj všeobecný náhľad o prepojenosti týchto procesov ako aj ich začlenenie do kompaktného pohľadu na celkový proces transformácie energie v biologických organizmoch), zloženia štruktúry a funkčnosti biologických membrán (táto oblast je nevyhnutná pre lepšie pochopenie poznatkov, ktoré sú uvedené v nasledujúcich kapitolách). V nasledujúcich kapitolách sa učebný text zaoberá popisom štruktúry a funkcie mitochondrií, pričom veľký dôraz je dávaný na popis vlastností a mechanizmov fungovania štyroch komplexov dýchacieho reťazca a ATP-syntázy. Tieto komplexy vytvárajú podmienky pre existenciu “najdôležitejšieho” bioenergetického procesu, oxidatívnej fosforylácie. V záverečných dvoch kapitolách sú uvedené mechanizmy procesov vytvárajúcich fotosyntézu, jej svetlej aj tmavej fázy. Sú tu relevantné informácie o tomto “druhom” najdôležitejšom bioenergetickom procese prebiehajúcom v mnohých biologických organizmoch a poskytujúcom možnosť transformácie enrgie elektromagnetického žiarenia na energiu “ukrytú” v chemických väzbách určitých chemických molekúl. Chceme vyjadriť naše presvedčenie, že predložené učebné texty “Bioenergetika” budú dobrým “pomocníkom a inšpirátorom” pre mnohých študentov, ktorí sa budú chcieť dozvedieť čo najviac o fascinujúcich štruktúrach a mechanizmoch umožňujúcich transformáciu energie v živých systémoch, bez ktorej by nebola možná existencia života ako ho poznáme. Želáme príjemné a podnetné čítanie a štúdium. URL: www.unibook.upjs.sk The textbook "Bioenergetics" should serve as an introduction to the study of bioenergetics. This field of science is currently highly actual, as the results of the bioenergetics research in recent years clearly show that bioenergetics processes in living systems can "serve" not only to transformation of energy, but also affect the course of processes such as apoptosis, aging, origin and development of many diseases (especially neurodegenerative). These facts clearly indicate the need for the existence of quality teaching texts that would allow students to acquire the necessary information and knowledge in this scientific discipline in an acceptable way. For the above mentioned reasons, we decided to create these textbooks, which are in the form of ten chapters, which naturally and logically follow each other. One chapter basically presents one lecture within the course of Bioenergetics, which is realized at the Faculty of Science of the Pavel Jozef Šafárik University in Košice at the master's and doctoral degree of the study program "Biophysics". At the same time, these texts can also be used for teaching in the study subject Biochemistry, which is taught in the bachelor's and master's degree programs of the study programs "Biochemistry" resp. “Biophysics”. We would like to express our conviction that these textbooks could in some way also help researchers working in the field of the energy transformation in biological organisms and the phenomena associated with this transformation. These textbooks present knowledge about the basic concepts of bioenergetics, the mechanisms of processes such as glycolysis and the Krebs cycle (in addition to a detailed and comprehensive description of these processes, there is also a general view of the interconnectedness of these processes and their incorporation into a compact view of the overall energy transformation in biological organisms), the structure and functionality of biological membranes (this area is necessary for a better understanding of the knowledge presented in the following chapters). In the following chapters, the textbook deals with the description of the structure and function of mitochondria, with great emphasis on the properties and mechanisms of functioning of the four complexes of the respiratory chain and ATP-synthase. These complexes create the basis for the existence of the "most important" process in bioenergetics, oxidative phosphorylation. In the final two chapters, the mechanisms of the processes that produce photosynthesis, its light and dark phases, are presented. There is relevant information about this "second" most important bioenergetics process taking place in many biological organisms and providing the possibility of transforming the energy of electromagnetic radiation into energy "hidden" in the chemical bonds of certain chemical molecules. We want to express our conviction that the textbooks "Bioenergetics" will be a good "helper and inspirer" for many students who want to learn as much as possible about the fascinating structures and mechanisms for energy transformation in living systems, without which it would not be possible existence of life as we know it.

This chapter presents an overview of the developments of feminist perspectives in music therapy. The authors outline the history of feminist thought in music therapy and how this framework applies to the discipline and profession of music therapy. Basic tenets of feminism are described including the importance placed on valuing women’s perspectives, egalitarianism, examining social constructs, examining discursive practices, and empowerment. Additionally, systems of oppression are considered with reference to inequalities that exist within the field of music therapy. The chapter ends with an examination of ways in which a feminist framework can inform assessment, clinical practice, research, ethics, and pedagogy in music therapy.

The chapter aimed to provide a brief account of the clinical method of Karl Jaspers, along with a thorough presentation of his “hierarchical principle”, of his approach to systematic classification in psychiatry and of the aftermath of hierarchical classification concepts in the clinical psychiatric settings. A detailed historical perspective of how the Jaspers theories have influenced the subsequent classification systems and a comparison with operationalized diagnostic approaches are also presented, unveiling the most common shortcomings of the current diagnostic classifications in psychiatry. Furthermore, the role of the “inner perspective” and of the phenomenological description of subjective experiences in the clinical field is discussed, also in connection with the implications for research in psychiatry and the various intellectual frameworks for this scientific discipline.

Medical law relating to obstetric anaesthesia has unique issues. There are legal implications of caring for two patients simultaneously, mother and fetus, and issues may arise when the welfare of one is in conflict with that of the other. This chapter addresses the extent to which a woman can be forced to consider the needs of her fetus, case law relating to enforced caesarean sections, and the current legal position. Although the majority of expectant mothers have capacity, there are situations where this may not be the case. Law concerning the care of teenage obstetric patients, the difficult areas of capacity and consent in labour, and the role of birth plans are therefore explored. Fundamental topics in medical law such as battery, negligence, manslaughter, and confidentiality are addressed, in addition to law relating to the teaching and supervision of junior medical staff, and clinical research and its publication. The chapter also considers areas of developing importance such as the legal implication of clinical guidelines and the degree to which these may be viewed as a standard of care. Finally, the chapter offers, where possible, the obstetric anaesthetist some practical guidance on incorporating the current legal position in these key areas of medical law into everyday practice.

Neurorehabilitation is an expanding field with an increasing clinical impact because of an ageing population. During the last 20 years it has developed from a discipline with little scientific background, separated from other medical centres, to a medical entity largely based on the principles of evidenced based medicine (EBM), with strong ties to basic research and clinical neurology. Today neurorehabilitation is still an emerging field, and treatment standards are not yet established, and there are very few resources that address contemporary neurorehabilitation from this perspective. This online title moves the reader from theory to practice. It provides the reader with an understanding of the theoretical underpinnings of neurorehabilitation, as well as a clear idea about how (and why) to approach treatment decisions in individual patients. Clinical recommendations are based on a mix of established evidence and clinical experience that the authors bring to bear on their topics.

Mayo Clinic Illustrated Textbook of Neurogastroenterology reflects experience covering the spectrum and maturation of the field of gastrointestinal motility— from studies of exotic patterns of myoelectric recordings in research laboratories to a clinical discipline with major advances in the clinical management of thousands of patients seen by gastroenterologists, primary care physicians, surgeons, or neurologists. Development of the specialty has been characterized by advances in imaging, developments of methods to measure diverse motor and sensory functions from the stomach to the anorectum, introduction of genetic testing, and a plethora of novel pharmacologic and interventional therapies that have revolutionized its practice. The book covers the spectrum of neurogastroenterologic disorders: from those that are associated with genetic and molecular disorders, through disturbances of the extrinsic neural control or the enteric neuromuscular apparatus, to dysfunction associated with disorders of the gut-brain axis; it reflects a desire to pass on clinical and mechanistic insights and advances in therapies that are relevant to a diverse spectrum of clinicians or clinicians in training who care for the estimated 40% of patients presenting to gastroenterologists with symptoms suggestive of disorders of stomach, intestinal, colonic, or anorectal function.

The Acute Care of at-Risk Newborns (ACoRN) program trains health care providers to stabilize that most challenging and enigmatic of medical patients: the unwell newborn. Early assessment, intervention, and management of at-risk or unstable infants can be critical for their survival and long-term health. Clinical care standards and educational programs to address these requirements are needed. The ACoRN program provides a unique, prioritized, and systematic approach to newborn stabilization for health care professionals with any degree of experience. ACoRN-trained providers learn to gather information, prioritize, intervene appropriately, and deliver high quality care to at-risk and unwell newborns in any setting. Because research and practice have advanced dramatically in recent years, the need for a new ACoRN text, the program’s centrepiece, became essential—hence the development of this new edition, which reflects current guidelines and evidence-based best practices. ACoRN teaches the concepts and skills required to stabilize unwell newborns through system-based algorithms (Sequences), each with its own chapter: respiratory, cardiovascular, neurology, surgical conditions, fluid and glucose, jaundice, thermoregulation, and infection. The ACoRN mnemonic defines stabilization steps and chapter structure: alerting signs, core steps, organization of care, response, next steps, and specific diagnosis and management. Each chapter includes educational objectives, key concepts, learning points, and at least one case scenario with questions and answers to reinforce content and learnings. This book is written for any health professional who may be required to participate in the stabilization of sick or preterm babies within their scope of practice.

This book presents investigative advances in psychology related to the lines of research of the Department of Psychology of the Catholic University of Colombia, whose central purpose is the generation of new knowledge with social repercussions. In this sense, the studies presented within the framework of the lines of Educational Psychology, Clinical Psychology, Health and Addictions, Psychobiological and Behavioral Processes, Legal Psychology and Criminology, Social, Political and Community Psychology, and Research Methods applied to the behavioral sciences, although oriented from different perspectives and methodologies, they unite in the same purpose: to strengthen their approach towards problems of social relevance without losing their contribution to psychological discipline. As a consequence, this book presents an enriched thematic variety directly related to the lines of research such as credibility of the testimony, adolescent domestic violence, cognitive training in older adults, family functioning and quality of life, emotional reparation in survivors of sexual violence in the middle of the Colombian armed conflict, dissatisfaction with body image, relational therapy, acceptance and commitment therapy in victims of the Colombian armed conflict, the relationship between physical activity and academic performance, and organizational change. The results of the studies can be problematized and vitalized in different application contexts.

Interdisciplinary Pediatric Palliative Care provides a uniquely integrated, comprehensive resource about palliative care for seriously ill children and their families. The field of palliative care is based on the fundamental principle that an interdisciplinary team is optimal in caring for patients and their families throughout the illness trajectory. The text integrates themes including goals of care, discipline-specific roles, cultural and spiritual considerations, evidence-based outcomes, and far more. It emphasizes the value of words and high-quality communication in palliative care. Importantly, content acknowledges challenging periods between team members and how those can ultimately benefit team, patient, and family care outcomes. Each chapter includes the perspective of the family of a seriously ill child in the form of a vignette to promote care team understanding of this crucial perspective. This second edition is founded on a wealth of evidence that reflects the innovations in pediatric palliative care science over the past 10 years, including initiatives in clinical care, research, and education. Interdisciplinary Pediatric Palliative Care is appropriate for all pediatric palliative clinicians, including physicians, nurses, psychosocial clinicians, chaplains, and many others. All subspecialists who deliver care to seriously ill children will find this book a must-have for their work.

Ketogenic diets have been used to treat epilepsy for nearly a century. Alongside enduring clinical success with a ketogenic diet, metabolism’s critical role in health and in diseases in the central nervous system and throughout the body is increasingly appreciated. Furthermore, metabolism-based strategies have been proven equal or even superior to pharmacological treatments in specific cases and for specific diseases. Rather than causing unwanted off-target pharmacological side effects, addressing metabolic dysfunction can improve overall health simultaneously. Enduring interest in the ketogenic diet’s proven efficacy in stopping seizures and emerging efficacy in other disorders has fueled renewed efforts to determine key mechanisms and diverse applications of metabolic therapies. In parallel, multiple strategies are being developed to mobilize similar metabolic benefits without reliance on such a strict diet. Research interest in metabolic therapies has spread into laboratories and clinics of every discipline, and could yield entirely new classes of drugs and treatment regimens. This work is the first comprehensive scientific resource on the ketogenic diet, covering the latest research into the mechanisms, established and emerging applications, metabolic alternatives, and implications for health and disease. Experts in clinical and basic research share their research into mechanisms spanning from ion channels to epigenetics, their insights based on decades of experience with the ketogenic diet in epilepsy, and their evidence for emerging applications ranging from autism to Alzheimer’s disease to brain cancer.

Although estrogens are best known for their roles in reproduction, they are also key modulators of brain regions that mediate learning and memory formation. This regulation has significant translational implications, as estrogens contribute to age-related memory decline and dementia, emotional disorders, addiction, and recovery from brain injury. Although the importance of estrogens for memory formation has been well accepted within the behavioral neuroendocrinology community, they have yet to be fully appreciated by neuroscientists outside of the discipline. The majority of researchers are not trained endocrinologists, and no previous monograph comprehensively encompasses the breadth of basic and clinical research on this subject. Estrogens and Memory: Basic Research and Clinical Implications provides a compendium of cutting-edge basic and clinical research describing the ways in which estrogens regulate memory in a variety of species. Chapters are written by leading experts whose work is on the forefront of this exciting field. The book is organized into three sections: effects of estrogens on the hippocampus and other brain regions central to memory, effects of estrogens on memory and related cognitive processes throughout the lifespan, and translational implications of estrogenic regulation of memory for aging and disease. This book gives an insider’s perspective on how hormonal regulation of brain function influences cognition and provides a one-stop reference for those interested in learning about the effects of estrogens on memory and the resulting implications for mental health.

This practitioner guide reviews screening, assessment, and treatment of substance use disorders (SUDs). It is designed to accompany Managing Your Substance Use Disorder: Client Workbook and A Family Guide to Coping with Substance Use Disorders. The latter guide was added because each person with a SUD affects the family and concerned significant others. The information and strategies that the authors present can be used with clients who have any type of SUD. The guide focuses on strategies to reduce or stop substance use and change behaviors that challenge recovery. The information presented is derived from research, clinical, and recovery literature and from the authors’ extensive experience developing and managing a large continuum of clinical services, providing direct care, conducting quality improvement initiatives, participating in clinical trials, and teaching all disciplines in a large medical center and the community. This guide discusses professional approaches and attitudes toward individuals with SUDs, assessment, diagnostic formulation, psychosocial and pharmacotherapeutic treatments, and mutual support programs. It provides an overview of the recovery and relapse processes and practical strategies to address issues associated with SUDs. This guide is for practitioners from any discipline who encounter individuals with SUDs in addiction, mental health, psychiatric, private practice, or other settings such as social services and the criminal justice system. Even medical practitioners who do not specialize in addiction treatment can benefit from the information in this guide because individuals with SUDs are found in all types of healthcare settings.

The book Placebo Effects: Understanding the Other Side of Medical Care examines the importance and the role of placebos across all medical conditions. This book offers a comprehensive description of all aspects of placebo research, a discipline that is now becoming a melting pot of concepts and ideas for medicine and neuroscience. A modern approach to the placebo effect and medical care is emphasized and highlighted across a variety of conditions. The first part sets the stage for a better understanding of placebo effects. To do this, it approaches medical care from an evolutionary and neuroscientific perspective, which helps understand the other side of medical care; that is, the psychosocial component. In the second part, old and new concepts and findings are described, so as to improve understanding of the specific conditions treated in the following chapters. The third part is dedicated to the most studied conditions, such as pain, motor disorders, depression, the immune and endocrine systems, and the fourth part describes those conditions that have been investigated much less, such as the cardiovascular, respiratory, gastrointestinal and genitourinary systems. All clinical, ethical, and methodological problems and implications related to the placebo effect are discussed in the fifth part, whereas other conditions outside the healing context, such as sport and social psychology, are briefly described in the sixth part.

Allergies and Asthma: What Every Parent Needs to Know is an invaluable resource for parents and caregivers trying to cope with the challenges of childhood asthma and allergies. First published 10 years ago, this well-organized guide covers such topics as: Identifying allergies and asthma, Preventing attacks, Minimizing triggers and avoiding allergens, Choosing medications wisely, Explaining allergies to young children, Helping children of all ages manage symptoms, What to do if a potentially life-threatening allergic reaction or asthma attack occurs. Allergies and Asthma now provides updated information on allergies--including the latest findings on food allergies and treatments--along with new approaches for monitoring asthma control, with expanded recommendations for children. The second edition provides new guidance on medications, new recommendations on patient education in settings beyond the physician's office, and new advice for controlling environmental factors that can cause asthma symptoms. Table of Contents includes: Allergies and Asthma Explained, Establishing the Diagnosis, Skin Allergies, Hay Fever (Allergic Rhinitis), Food Allergies, Killer Allergies: Anaphalaxis, Approaches to Allergy Treatments, An Overview of Asthma, Common Asthma Triggers and How to Identify Them, Asthma in Infants and Toddlers, Approaches to Asthma Treatments, How Environmental and Lifestyle Factors Affect Asthma Teaching Your Child the Basics of Self Care, Appendices, Hidden Sources of Food Allergens, Sources for Information About Allergies and Asthma, Sources of Allergy and Asthma Products, Practical Publications on Allergies and Asthma, Resources from the American Academy of Pediatrics, Glossary, and Index. About the Editor: Michael J. Welch, MD, FAAAAI, FAAP, CPI, is codirector of the Allergy and Asthma Medical Group and Research Center in San Diego, CA, and clinical professor at the University of California, San Diego School of Medicine. Dr Welch earned his medical degree at the University of California, Los Angeles, where he later completed an internship and residency in pediatrics and a fellowship in allergy/immunology. Dr Welch is a fellow of the American Academy of Pediatrics and the American Academy of Allergy, Asthma & Immunology. He is past president of the San Diego Allergy Society and the California Society of Allergy, Asthma and Immunology. He lives in San Diego.

For about one century the catalogue of books in phenomenological psychopathology has been tremendously rich in essays, but remarkably poor in handbooks. Even the cornerstone of our canon, Jaspers’ General Psychopathology, originally written as a textbook, can hardly be given to a student as a basic reading. This makes extremely difficult teaching the fundamentals of our discipline. Students ask for manualized knowledge expecting teachers to explain them what-exactly-must-be-done-in-a-given-circumstance. This Handbook is meant to fill these gaps. It includes a detailed, thorough and reader-friendly description of philosophical and clinical key-concepts and constructs, and of the contributions of leading figures of phenomenological psychopathology. It establishes clear connections between psychopathological knowledge and clinical practice. It liaise phenomenological psychopathology to contemporary debates in nosography, clinical epistemology, research and the neurosciences. It’s stronger benefit is that it brings together evidence-based with person-based knowledge. All learning is based on process of recognition. ‘Recognition’ means identification of someone or something from previous encounters or knowledge. In standard clinical training this process is called ‘diagnosis’ and evidence-based diagnostic skills are deemed fundamental. Students are spot-on when soliciting this kind of knowledge to be regimented and normalized. Yet ‘recognition’ has a second meaning: acknowledging the absolute singularity of what is out there. To recognize someone or something means to be able to tolerate its otherness. This kind of recognition is a practice in which epistemology is in touch with ethics. Whereas recognition qua identification or diagnosis is an act of recollection based on previously acquired knowledge, recognition qua acknowledgement is an ethical act of acceptance of the unique being-so of the other person or state of affairs. The Handbook of Phenomenological Psychopathology engages in bringing together these two kinds of ‘recognition’ and establish a solid as well as flexible framework for the clinic of mental disorders.