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1

Yang, Hai, Rui Chen, Dongdong Li, and Zhe Wang. "Subtype-GAN: a deep learning approach for integrative cancer subtyping of multi-omics data." Bioinformatics 37, no. 16 (2021): 2231–37. http://dx.doi.org/10.1093/bioinformatics/btab109.

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Abstract Motivation The discovery of cancer subtyping can help explore cancer pathogenesis, determine clinical actionability in treatment, and improve patients' survival rates. However, due to the diversity and complexity of multi-omics data, it is still challenging to develop integrated clustering algorithms for tumor molecular subtyping. Results We propose Subtype-GAN, a deep adversarial learning approach based on the multiple-input multiple-output neural network to model the complex omics data accurately. With the latent variables extracted from the neural network, Subtype-GAN uses consensu
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Huang, Dian, Chen Yu, Zongze Shao, et al. "Identification and Characterization of Nnematicidal Volatile Organic Compounds from Deep-Sea Virgibacillus dokdonensis MCCC 1A00493." Molecules 25, no. 3 (2020): 744. http://dx.doi.org/10.3390/molecules25030744.

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Root-knot nematode diseases cause severe yield and economic losses each year in global agricultural production. Virgibacillus dokdonensis MCCC 1A00493, a deep-sea bacterium, shows a significant nematicidal activity against Meloidogyne incognita in vitro. However, information about the active substances of V. dokdonensis MCCC 1A00493 is limited. In this study, volatile organic compounds (VOCs) from V. dokdonensis MCCC 1A00493 were isolated and analyzed through solid-phase microextraction and gas chromatography–mass spectrometry. Four VOCs, namely, acetaldehyde, dimethyl disulfide, ethylbenzene,
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Niu, Siwen, Dong Liu, Zongze Shao, Jiang Huang, Aili Fan, and Wenhan Lin. "Chlorinated metabolites with antibacterial activities from a deep-sea-derived Spiromastix fungus." RSC Advances 11, no. 47 (2021): 29661–67. http://dx.doi.org/10.1039/d1ra05736g.

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4

Morshed, Ahsan, Prem Prakash Jayaraman, Timos Sellis, Dimitrios Georgakopoulos, Massimo Villari, and Rajiv Ranjan. "Deep Osmosis: Holistic Distributed Deep Learning in Osmotic Computing." IEEE Cloud Computing 4, no. 6 (2017): 22–32. http://dx.doi.org/10.1109/mcc.2018.1081070.

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Geng, Huantong, and Liangchao Geng. "MCCS-LSTM: Extracting Full-Image Contextual Information and Multi-Scale Spatiotemporal Feature for Radar Echo Extrapolation." Atmosphere 13, no. 2 (2022): 192. http://dx.doi.org/10.3390/atmos13020192.

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Precipitation nowcasting has been gaining importance in the operational weather forecast, being essential for economic and social development. Conventional methods of precipitation nowcasting are mainly focused on the task of radar echo extrapolation. In recent years, deep learning methods have been used in this task. Nevertheless, raising the accuracy and extending the lead time of prediction remains as a challenging problem. To address the problem, we proposed a Multi-Scale Criss-Cross Attention Context Sensing Long Short-Term Memory (MCCS-LSTM). In this model, Context Sensing framework (CS
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Xiao, Jing, Yingxue Luo, Shujie Xie, and Jun Xu. "Serinicoccus profundi sp. nov., an actinomycete isolated from deep-sea sediment, and emended description of the genus Serinicoccus." International Journal of Systematic and Evolutionary Microbiology 61, no. 1 (2011): 16–19. http://dx.doi.org/10.1099/ijs.0.019976-0.

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A Gram-reaction-positive bacterial strain of the genus Serinicoccus, designated MCCC 1A05965T, was isolated from a deep-sea (5368 m) sediment of the Indian Ocean. Comparison of 16S rRNA gene sequences revealed that the isolate shared 97.6 % sequence similarity with Serinicoccus marinus JC1078T, the type strain of the only described species of the genus Serinicoccus. The DNA–DNA relatedness between these two strains was 46.2 % (standard deviation 1.86 %). The cell wall contained alanine, glycine, serine, l-ornithine and glutamic acid, which corresponds to the description of the genus Serinicocc
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7

Niu, Siwen, Chun-Lan Xie, Tianhua Zhong, et al. "Sesquiterpenes from a deep-sea-derived fungus Graphostroma sp. MCCC 3A00421." Tetrahedron 73, no. 52 (2017): 7267–73. http://dx.doi.org/10.1016/j.tet.2017.11.013.

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8

Mehta, Sanket, Nicholas C. Danford, Venkat Boddapati, Bonnie Y. Chien, and Justin K. Greisberg. "Discriminative Ability for Adverse Outcomes in Traumatic Ankle Fracture: A Comparison of the Modified Charlson Comorbidity Index, Elixhauser Comorbidity Measure, and Modified Frailty Index." Foot & Ankle Orthopaedics 7, no. 4 (2022): 2473011421S0080. http://dx.doi.org/10.1177/2473011421s00803.

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Category: Trauma; Ankle Introduction/Purpose: The modified Charlson Comorbidity Index (mCCI), Elixhauser comorbidity measure (ECM), and 5- factor modified Frailty Index (mFI-5) have been validated for the purpose of outcome prediction in foot and ankle orthopedic care. However, from the perspective of clinical utility, no study has sought to compare the predictive performance of these measures specifically following traumatic ankle fracture. The present study compares the discriminative ability of the mCCI, ECM, and mFI-5, as well as various demographic characteristics, such as age, gender, an
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9

Chen, Wen, Jinping Wang, Dian Huang, et al. "Volatile Organic Compounds from Bacillus aryabhattai MCCC 1K02966 with Multiple Modes against Meloidogyne incognita." Molecules 27, no. 1 (2021): 103. http://dx.doi.org/10.3390/molecules27010103.

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Plant-parasitic nematodes cause severe losses to crop production and economies all over the world. Bacillus aryabhattai MCCC 1K02966, a deep-sea bacterium, was obtained from the Southwest Indian Ocean and showed nematicidal and fumigant activities against Meloidogyne incognita in vitro. The nematicidal volatile organic compounds (VOCs) from the fermentation broth of B. aryabhattai MCCC 1K02966 were investigated further using solid-phase microextraction gas chromatography-mass spectrometry. Four VOCs, namely, pentane, 1-butanol, methyl thioacetate, and dimethyl disulfide, were identified in the
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10

He, Zhi-Hui, Jia Wu, Lin Xu, et al. "Chemical Constituents of the Deep-Sea-Derived Penicillium solitum." Marine Drugs 19, no. 10 (2021): 580. http://dx.doi.org/10.3390/md19100580.

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A systematic chemical investigation of the deep-sea-derived fungus Penicillium solitum MCCC 3A00215 resulted in the isolation of one novel polyketide (1), two new alkaloids (2 and 3), and 22 known (4–25) compounds. The structures of the new compounds were established mainly on the basis of exhaustive analysis of 1D and 2D NMR data. Viridicatol (13) displayed moderate anti-tumor activities against PANC-1, Hela, and A549 cells with IC50 values of around 20 μM. Moreover, 13 displayed potent in vitro anti-food allergic activity with an IC50 value of 13 μM, compared to that of 92 μM for the positiv
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Niu, Siwen, Jin-Mei Xia, Zengpeng Li, et al. "Aphidicolin Chemistry of the Deep-Sea-Derived Fungus Botryotinia fuckeliana MCCC 3A00494." Journal of Natural Products 82, no. 8 (2019): 2307–31. http://dx.doi.org/10.1021/acs.jnatprod.9b00705.

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12

Liu, Chih-Yi, Nai-Wen Kang, Kengo Takeuchi, and Shih-Sung Chuang. "Combined Merkel Cell Carcinoma with Nodal Presentation: Report of a Case Diagnosed with Excisional but Not Incisional Biopsy and Literature Review." Diagnostics 13, no. 3 (2023): 449. http://dx.doi.org/10.3390/diagnostics13030449.

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Merkel cell carcinoma (MCC) is a rare primary neuroendocrine carcinoma (NEC) of the skin. As compared to pure MCCs, combined MCCs are aggressive and exhibit a higher probability of metastasis. A correct diagnosis might be missed, especially when the biopsy sample is too small or too superficial. We report a 79-year-old Taiwanese male who presented with lymphadenopathy suspicious for lymphoma. A nodal biopsy showed metastatic NEC. A skin tumor in the lower back was identified, and an incisional biopsy showed only squamous cell carcinoma (SCC). A subsequent excisional biopsy was performed based
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13

Niu, Siwen, Shuhuan Huang, Bihong Hong, et al. "Antiviral Cyclopropane Acids from Deep-Sea-Derived Fungus Aspergillus sydowii." Marine Drugs 20, no. 7 (2022): 410. http://dx.doi.org/10.3390/md20070410.

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Four novel monocyclic cyclopropane acids, namely, sydocyclopropanes A–D (1–4), along with one known congener hamavellone B (5), were isolated from the Aspergillus sydowii MCCC 3A00324 fungus, which was isolated from the deep-sea sediment. The gross structures of novel compounds were established by detailed analyses of the spectroscopic data (HRESIMS and NMR spectra), and their absolute configurations were resolved on the basis of the quantum chemical calculations of ECD and NMR data, in association with DP4+ probability analyses. Sydocyclopropanes A–D, featuring the 1,1,2,3-tetrasubstituted cy
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Donizy, Piotr, Joanna P. Wróblewska, Dora Dias-Santagata, et al. "Merkel Cell Carcinoma of Unknown Primary: Immunohistochemical and Molecular Analyses Reveal Distinct UV-Signature/MCPyV-Negative and High Immunogenicity/MCPyV-Positive Profiles." Cancers 13, no. 7 (2021): 1621. http://dx.doi.org/10.3390/cancers13071621.

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Background: Merkel cell carcinomas of unknown primary (MCC-UPs) are defined as deep-seated tumors without an associated cutaneous tumor. Although the distinction has important clinical implications, it remains unclear whether these tumors represent primary tumors of lymph nodes or metastatic cutaneous primaries. Methods: We compared the immunohistochemical profiles of four groups of MCCs (Merkel cell polyomavirus (MCPyV)-positive UP, MCPyV-negative UP, MCPyV-positive known primary (KP), and MCPyV-negative KP) using B-cell and pre-B-cell markers, cell cycle regulating proteins, follicular stem
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Xing, Cui-Ping, Dan Chen, Chun-Lan Xie, et al. "Anti-Food Allergic Compounds from Penicillium griseofulvum MCCC 3A00225, a Deep-Sea-Derived Fungus." Marine Drugs 19, no. 4 (2021): 224. http://dx.doi.org/10.3390/md19040224.

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Ten new (1–10) and 26 known (11–36) compounds were isolated from Penicillium griseofulvum MCCC 3A00225, a deep sea-derived fungus. The structures of the new compounds were determined by detailed analysis of the NMR and HRESIMS spectroscopic data. The absolute configurations were established by X-ray crystallography, Marfey’s method, and the ICD method. All isolates were tested for in vitro anti-food allergic bioactivities in immunoglobulin (Ig) E-mediated rat basophilic leukemia (RBL)-2H3 cells. Compound 13 significantly decreased the degranulation release with an IC50 value of 60.3 μM, compar
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Hao, You-Jia, Zheng-Biao Zou, Ming-Min Xie, et al. "Ferroptosis Inhibitory Compounds from the Deep-Sea-Derived Fungus Penicillium sp. MCCC 3A00126." Marine Drugs 21, no. 4 (2023): 234. http://dx.doi.org/10.3390/md21040234.

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Two new xanthones (1 and 2) were isolated from the deep-sea-derived fungus Penicillium sp. MCCC 3A00126 along with 34 known compounds (3–36). The structures of the new compounds were established by spectroscopic data. The absolute configuration of 1 was validated by comparison of experimental and calculated ECD spectra. All isolated compounds were evaluated for cytotoxicity and ferroptosis inhibitory activities. Compounds 14 and 15 exerted potent cytotoxicity against CCRF-CEM cells, with IC50 values of 5.5 and 3.5 μM, respectively, whereas 26, 28, 33, and 34 significantly inhibited RSL3-induce
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17

Zhang, Yu, Jianguo Yao, and Haibing Guan. "Intelligent Cloud Resource Management with Deep Reinforcement Learning." IEEE Cloud Computing 4, no. 6 (2017): 60–69. http://dx.doi.org/10.1109/mcc.2018.1081063.

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18

Xie, Chun-Lan, Qingmei Liu, Jin-Mei Xia, et al. "Anti-Allergic Compounds from the Deep-Sea-Derived Actinomycete Nesterenkonia flava MCCC 1K00610." Marine Drugs 15, no. 3 (2017): 71. http://dx.doi.org/10.3390/md15030071.

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19

Niu, Siwen, Manli Xia, Mingliang Chen, et al. "Cytotoxic Polyketides Isolated from the Deep-Sea-Derived Fungus Penicillium chrysogenum MCCC 3A00292." Marine Drugs 17, no. 12 (2019): 686. http://dx.doi.org/10.3390/md17120686.

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The chemical examination of the solid cultures of the deep-sea-derived fungus Penicillium chrysogenum MCCC 3A00292 resulted in the isolation of three new versiol-type analogues, namely peniciversiols A–C (1–3), and two novel lactone derivatives, namely penicilactones A and B (6 and 7), along with 11 known polyketides. The planar structures of the new compounds were determined by the comprehensive analyses of the high-resolution electrospray ionization mass spectroscopy (HRESIMS) and nuclear magnetic resonance (NMR) data, while their absolute configurations were resolved on the basis of compari
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20

Ma, Xin-hua, Wei-min Zheng, Kai-hui Sun, et al. "Two new phenylspirodrimanes from the deep-sea derived fungus Stachybotrys sp. MCCC 3A00409." Natural Product Research 33, no. 3 (2018): 386–92. http://dx.doi.org/10.1080/14786419.2018.1455041.

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21

Xing, Cui-Ping, Jia Wu, Jin-Mei Xia, Shao-Qiang Fan, and Xian-Wen Yang. "Steroids and anthraquinones from the deep-sea-derived fungus Aspergillus nidulans MCCC 3A00050." Biochemical Systematics and Ecology 83 (April 2019): 103–5. http://dx.doi.org/10.1016/j.bse.2018.12.012.

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22

Niu, Siwen, Zuowang Fan, Xixiang Tang, et al. "Cyclopiane-type diterpenes from the deep-sea-derived fungus Penicillium commune MCCC 3A00940." Tetrahedron Letters 59, no. 4 (2018): 375–78. http://dx.doi.org/10.1016/j.tetlet.2017.12.045.

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23

van der Pas, J. W. G. M., W. E. Walker, V. A. W. J. Marchau, G. P. Van Wee, and D. B. Agusdinata. "Exploratory MCDA for handling deep uncertainties: the case of intelligent speed adaptation implementation." Journal of Multi-Criteria Decision Analysis 17, no. 1-2 (2010): 1–23. http://dx.doi.org/10.1002/mcda.450.

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24

Marco Ivaldi, Andrea Ciavattini, and Cugliari Giovanni. "Heart rate analysis during very deep dives in flooded caves: single case study." International Journal of Physical Education, Fitness and Sports 9, no. 3 (2020): 9–17. http://dx.doi.org/10.34256/ijpefs2032.

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The purpose of this study is to investigate the heart rate adaptations during deep dave diving with MCCR (mechanical closed circuit rebreather). Previous studies on this matter have not been conducted to the depths reached in this study and most of them have been conducted inside hyperbaric chambers trying to recreate the immersion conditions. The data collection took place during the exploration of two hydrogeological sites by a professional cave diver. The recordings were made using a SCUBAPRO GALILEO SOL® dive computer capable of monitoring the heart rate, with a sampling interval of 0,25 H
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Antonsdottir, Inga, Quincy Samus, Melissa Reuland, Deirdre Johnston, Morgan Spliedt, and Danetta Sloan. "Staff Perspectives on Lessons Learned From an Interdisciplinary Memory Care Coordination Program." Innovation in Aging 5, Supplement_1 (2021): 325. http://dx.doi.org/10.1093/geroni/igab046.1263.

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Abstract MIND at Home is a home-based care coordination program for persons living with dementia (PLWD) and their informal care partners (CP). Assessments, care planning and coordination is delivered by trained non-clinical Memory Care Coordinators (MCCs), working together on an interdisciplinary team with nurses and geriatric psychiatrists. We report qualitative results from program staff (two nurses and eight MCCs) who implemented the program in the context of two clinical trials. Care team respondents answered open-ended questions covering 5 domains pertaining to: helpful skillsets; positiv
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Taylor, H., J. McDonald, J. I. Serrano Contreras, J. Li, J. Marchesi, and A. Hart. "DOP08 Deep remission in paediatric Crohn’s disease is associated with increased abundance of dialister species and increased valerate." Journal of Crohn's and Colitis 14, Supplement_1 (2020): S045—S046. http://dx.doi.org/10.1093/ecco-jcc/jjz203.047.

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Abstract Background Deep remission, or the absence of mucosal inflammation on endoscopy, is associated with improved long-term outcomes in paediatric Crohn’s disease (pCD). In pCD faecal calprotectin level <100 mg/l is a validated non-invasive marker of deep remission and is a therapeutic target used in clinical practice. The microbiome in pCD has been extensively compared with controls and is known to have reduced diversity, high instability, and depleted short-chain fatty acid (SCFA) producers. This study investigates variation in microbiome, metabolome and protease activity associate
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Tang, Xi-Xiang, Shun-Zhi Liu, Xia Yan, et al. "Two New Cytotoxic Compounds from a Deep-Sea Penicillum citreonigrum XT20-134." Marine Drugs 17, no. 9 (2019): 509. http://dx.doi.org/10.3390/md17090509.

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Penicillum citreonigrum XT20-134 (MCCC 3A00956) is a fungus with cytotoxic activity, derived from deep-sea sediment. Five new compounds, adeninylpyrenocine (1), 2-hydroxyl-3-pyrenocine-thio propanoic acid (2), ozazino-cyclo-(2,3-dihydroxyl-trp-tyr) (3), 5,5-dichloro-1-(3,5-dimethoxyphenyl)-1,4-dihydroxypentan-2-one (4), and 2,3,4-trihydroxybutyl cinnamate (5), together with 19 known compounds (6–24), were isolated from an ethyl acetate (EtOAc) extract of its fermentation. The structures of the new compounds were comprehensively characterized by high-resolution electrospray ionization-mass spec
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Zou, Zheng-Biao, Gang Zhang, Yu-Qi Zhou, et al. "Chemical Constituents of the Deep-Sea-Derived Penicillium citreonigrum MCCC 3A00169 and Their Antiproliferative Effects." Marine Drugs 20, no. 12 (2022): 736. http://dx.doi.org/10.3390/md20120736.

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Six new citreoviridins (citreoviridins J–O, 1–6) and twenty-two known compounds (7–28) were isolated from the deep-sea-derived Penicillium citreonigrum MCCC 3A00169. The structures of the new compounds were determined by spectroscopic methods, including the HRESIMS, NMR, ECD calculations, and dimolybdenum tetraacetate-induced CD (ICD) experiments. Citreoviridins J−O (1–6) are diastereomers of 6,7-epoxycitreoviridin with different chiral centers at C-2–C-7. Pyrenocine A (7), terrein (14), and citreoviridin (20) significantly induced apoptosis for HeLa cells with IC50 values of 5.4 μM, 11.3 μM,
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Lai, Qiliang, Liping Wang, Yuhui Liu, Jun Yuan, Fengqin Sun, and Zongze Shao. "Parvibaculum indicum sp. nov., isolated from deep-sea water." International Journal of Systematic and Evolutionary Microbiology 61, no. 2 (2011): 271–74. http://dx.doi.org/10.1099/ijs.0.021899-0.

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A taxonomic study was carried out on strain P31T, which was isolated from a polycyclic aromatic hydrocarbon (PAH)-degrading consortium enriched with deep-sea water of the Indian Ocean. The isolate was Gram-reaction-negative, rod-shaped, motile by means of a polar flagellum and incapable of reducing nitrate to nitrite. Growth was observed at 0.5–8 % NaCl and at 10–41 °C. Strain P31T was unable to degrade Tween 80 or gelatin. The major respiratory quinone was ubiquinone 11 (Q-11). The dominant fatty acids were C18 : 1 ω7c (39.79 %), 11-methyl C18 : 1 ω7c (17.84 %), C19 : 0 cyclo ω8c (12.05 %) an
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Lai, Qiliang, Yuanyuan Fu, Jianning Wang, et al. "Citreicella marina sp. nov., isolated from deep-sea sediment." International Journal of Systematic and Evolutionary Microbiology 61, no. 4 (2011): 728–31. http://dx.doi.org/10.1099/ijs.0.022376-0.

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A taxonomic study was carried out on a novel strain, designated CK-I3-6T, which was isolated from deep-sea sediment of the south-west Indian Ocean Ridge. Cells were Gram-reaction-negative, oxidase- and catalase-positive, rod-shaped and non-motile. Growth was observed at 4–38 °C and in 1–12 % (w/v) NaCl. Cells were able to degrade gelatin and oxidize thiosulfate but did not reduce nitrate. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain CK-I3-6T belonged to the genus Citreicella with a sequence similarity of 97.3 % to Citreicella thiooxidans CHLG 1T, while similarit
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Lai, Qiliang, Zhiwei Yu, Jun Yuan, Fengqin Sun, and Zongze Shao. "Nitratireductor indicus sp. nov., isolated from deep-sea water." International Journal of Systematic and Evolutionary Microbiology 61, no. 2 (2011): 295–98. http://dx.doi.org/10.1099/ijs.0.022962-0.

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A taxonomic study was carried out on a novel bacterial strain, designated C115T, isolated from a crude-oil-degrading consortium, enriched from deep-sea water of the Indian Ocean. Cells were Gram-negative short rods, mobile by means of a monopolar flagellum. Growth was observed at salinities of 0–7 % and at 10–43 °C. It was unable to degrade Tween 80 or gelatin. 16S rRNA gene sequence analysis showed that strain C115T was related most closely to Nitratireductor aquibiodomus NL21T (96.5 % similarity), Nitratireductor kimnyeongensis KY 101T (96.4 %) and Nitratireductor basaltis J3T (96.2 %). The
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Xu, Hui, Yuanyuan Fu, Ning Yang, Zhixin Ding, Qiliang Lai, and Runying Zeng. "Flammeovirga pacifica sp. nov., isolated from deep-sea sediment." International Journal of Systematic and Evolutionary Microbiology 62, Pt_4 (2012): 937–41. http://dx.doi.org/10.1099/ijs.0.030676-0.

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Strain WPAGA1T was isolated from marine sediment of the west Pacific Ocean. Phylogenetic analysis based on 16S rRNA gene sequences indicated that the isolate belonged to the genus Flammeovirga . Strain WPAGA1T exhibited highest 16S rRNA gene sequence similarity with Flammeovirga yaeyamensis NBRC 100898T (98.1 %) and lower sequence similarity with Flammeovirga arenaria IFO 15982T (94.6 %) and other members of the genus Flammeovirga (<94.2 %). DNA–DNA relatedness studies showed that strain WPAGA1T was distinct from F. yaeyamensis NBRC 100898T and F. arenaria NBRC 15982T (43±4 % and 32±2 % rel
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Li, Guizhen, Qiliang Lai, Yaping Du, Xiupian Liu, Fengqin Sun, and Zongze Shao. "Marinibacterium profundimaris gen. nov., sp. nov., isolated from deep seawater." International Journal of Systematic and Evolutionary Microbiology 65, Pt_11 (2015): 4175–79. http://dx.doi.org/10.1099/ijsem.0.000557.

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A taxonomic study was carried out on strain 22II1-22F33T, which was isolated from deep seawater of the Atlantic Ocean. The bacterium was Gram-stain-negative, oxidase-positive and weakly catalase-positive, oval in shape without flagellum. Growth was observed at salinities of 0–12 % and at temperatures of 4–41 °C. The isolate was capable of hydrolysing aesculin and Tween 80 and reduction of nitrate to nitrite, but unable to hydrolyse gelatin. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain 22II1-22F33T belongs to the family Rhodobacteraceae, with highest sequence sim
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Niu, Siwen, Longhe Yang, Tingting Chen, et al. "New Monoterpenoids and Polyketides from the Deep-Sea Sediment-Derived Fungus Aspergillus sydowii MCCC 3A00324." Marine Drugs 18, no. 11 (2020): 561. http://dx.doi.org/10.3390/md18110561.

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Chemical study of the secondary metabolites of a deep-sea-derived fungus Aspergillus sydowii MCCC 3A00324 led to the isolation of eleven compounds (1–11), including one novel (1) and one new (2) osmane-related monoterpenoids and two undescribed polyketides (3 and 4). The structures of the metabolites were determined by comprehensive analyses of the NMR and HRESIMS spectra, in association with quantum chemical calculations of the 13C NMR, ECD, and specific rotation data for the configurational assignment. Compound 1 possessed a novel monoterpenoid skeleton, biogenetically probably derived from
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Niu, Siwen, Dong Liu, Zongze Shao, Peter Proksch, and Wenhan Lin. "Eutypellazines A–M, thiodiketopiperazine-type alkaloids from deep sea derived fungus Eutypella sp. MCCC 3A00281." RSC Advances 7, no. 53 (2017): 33580–90. http://dx.doi.org/10.1039/c7ra05774a.

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36

Li, Guizhen, Qiliang Lai, Yaping Du, Xiupian Liu, Fengqin Sun, and Zongze Shao. "Aestuariivita atlantica sp. nov., isolated from deep-sea sediment." International Journal of Systematic and Evolutionary Microbiology 65, Pt_10 (2015): 3281–85. http://dx.doi.org/10.1099/ijsem.0.000406.

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A novel strain, 22II-S11-z3T, was isolated from the deep-sea sediment of the Atlantic Ocean. The bacterium was aerobic, Gram-staining-negative, oxidase-positive and catalase-negative, oval- to rod-shaped, and non-motile. Growth was observed at salinities of 1–9 % NaCl and temperatures of 10–45 °C. The isolate could hydrolyse aesculin and Tweens 20, 40 and 80, but not gelatin. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain 22II-S11-z3T belonged to the genus Aestuariivita, with highest sequence similarity to Aestuariivita boseongensis KCTC 42052T (97.5 %). The avera
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Li, Jianyang, Mingming Qi, Qiliang Lai, Guangyi Wang, and Zongze Shao. "Sunxiuqinia indica sp. nov., isolated from deep sea." International Journal of Systematic and Evolutionary Microbiology 70, no. 7 (2020): 4186–92. http://dx.doi.org/10.1099/ijsem.0.004273.

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A Gram-stain-negative, facultative anaerobic, red-pigmented, rod-shaped and non-motile strain (RC1_OXG_1FT) was isolated from deep sea water of the Indian Ocean. It was able to grow at pH 5–8 (optimum, pH 7), at 5–37 °C (optimum, 30 °C), and at salinity (% NaCl, w/v) of 0.5–5 % (optimum, 1–2 %). Catalase- and oxidase-positive. It had highest 16S rRNA gene similarity (96.7 %) to ‘ Sunxiuqinia dokdonensis ’ DH1T, followed by Sunxiuqinia faeciviva JAM-BA0302T (96.6 %), Sunxiuqinia elliptica CGMCC 1.9156T (96.2 %), Sunxiuqinia rutila HG677T (96.0 %) and species (less than 92.3 %) of other genera.
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38

de Groot, Jos, and Steven Hijink. "Verslaggeving over ‘in-control’ door Nederlandse beursvennootschappen." Maandblad Voor Accountancy en Bedrijfseconomie 94, no. 11/12 (2020): 477–93. http://dx.doi.org/10.5117/mab.94.59763.

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De onderwerpen ‘in control’ en de ‘in-control statement’ worden in de praktijk op verschillende manieren geïnterpreteerd en uitgelegd. Tegelijkertijd is in het afgelopen jaar vanuit verschillende invalshoeken (hernieuwde) belangstelling getoond voor nieuwe regelgeving voor verslaggeving over ‘in-control’ zijn. Dit praktijkonderzoek van 91 jaarverslagen over 2019 van Nederlandse beursvennootschappen toont aan dat de bestuursverklaring uit de Code 2016 op alle vier de sub-elementen voor het overgrote deel wordt gevolgd door de AEX-, AMX- en AScX-fondsen. Bij de lokale beursvennootschappen behore
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Shao, Rui, Qiliang Lai, Xiupian Liu, et al. "Zunongwangia atlantica sp. nov., isolated from deep-sea water." International Journal of Systematic and Evolutionary Microbiology 64, Pt_1 (2014): 16–20. http://dx.doi.org/10.1099/ijs.0.054007-0.

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A taxonomic study was carried out on strain 22II14-10F7T, which was isolated from the deep-sea water of the Atlantic Ocean with oil-degrading enrichment. The bacterium was Gram-stain-negative, oxidase- and catalase-positive and rod-shaped. Growth was observed at salinities from 0.5 to 15 % and at temperatures from 4 to 37 °C; it was unable to hydrolyse Tween 40, 80 or gelatin. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain 22II14-10F7T represented a member of the genus Zunongwangia , with highest sequence similarity of 97.3 % to Zunongwangia profunda SM-A87T, whil
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Ozrazgat-Baslanti, Tezcan, Tyler J. Loftus, Yuanfang Ren, Matthew M. Ruppert, and Azra Bihorac. "Advances in artificial intelligence and deep learning systems in ICU-related acute kidney injury." Current Opinion in Critical Care 27, no. 6 (2021): 560–72. http://dx.doi.org/10.1097/mcc.0000000000000887.

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Xie, Chun-Lan, Qingmei Liu, Zhi-Hui He, et al. "Discovery of andrastones from the deep-sea-derived Penicillium allii-sativi MCCC 3A00580 by OSMAC strategy." Bioorganic Chemistry 108 (March 2021): 104671. http://dx.doi.org/10.1016/j.bioorg.2021.104671.

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42

Niu, Siwen, Ting-Ting Zhou, Chun-Lan Xie, Gai-Yun Zhang, and Xian-Wen Yang. "Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207." Marine Drugs 15, no. 7 (2017): 230. http://dx.doi.org/10.3390/md15070230.

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Huang, Dian, Zong-Ze Shao, Yi Yu, et al. "Identification, Characteristics and Mechanism of 1-Deoxy-N-acetylglucosamine from Deep-Sea Virgibacillus dokdonensis MCCC 1A00493." Marine Drugs 16, no. 2 (2018): 52. http://dx.doi.org/10.3390/md16020052.

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Niu, Siwen, Ning Wang, Chun-Lan Xie, et al. "Roquefortine J, a novel roquefortine alkaloid, from the deep-sea-derived fungus Penicillium granulatum MCCC 3A00475." Journal of Antibiotics 71, no. 7 (2018): 658–61. http://dx.doi.org/10.1038/s41429-018-0046-y.

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Niu, Siwen, Qingmei Liu, Jin-Mei Xia, et al. "Polyketides from the Deep-Sea-Derived Fungus Graphostroma sp. MCCC 3A00421 Showed Potent Antifood Allergic Activities." Journal of Agricultural and Food Chemistry 66, no. 6 (2018): 1369–76. http://dx.doi.org/10.1021/acs.jafc.7b04383.

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46

Lai, Qiliang, Junwei Cao, Jun Yuan, Fuying Li, and Zongze Shao. "Celeribacter indicus sp. nov., a polycyclic aromatic hydrocarbon-degrading bacterium from deep-sea sediment and reclassification of Huaishuia halophila as Celeribacter halophilus comb. nov." International Journal of Systematic and Evolutionary Microbiology 64, Pt_12 (2014): 4160–67. http://dx.doi.org/10.1099/ijs.0.069039-0.

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A taxonomic study was carried out on strain P73T, which was isolated from deep-sea sediment of the Indian Ocean by enrichment of polycyclic aromatic hydrocarbons. The strain was able to degrade biphenyl, naphthalene, 2-methylnaphthalene, 2,6-dimethylnaphthalene, acenaphthene, anthracene, phenanthrene, dibenzothiophene, dibenzofuran, fluorene, 4-methyldibenzothiophene and fluoranthene, but not pyrene or chrysene. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain P73T formed a clade with the genera Celeribacter and Huaishuia within the family Rhodobacteraceae , with highe
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Yang, Shanshan, Xuegong Li, Xiang Xiao, Guangjiao Zhuang, and Yu Zhang. "Sphingomonas profundi sp. nov., isolated from deep-sea sediment of the Mariana Trench." International Journal of Systematic and Evolutionary Microbiology 70, no. 6 (2020): 3809–15. http://dx.doi.org/10.1099/ijsem.0.004235.

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A Gram-stain-negative, short rod-shaped, yellow bacterium (strain LMO-1T) was isolated from deep-sea sediment of the Mariana Trench, Challenger Deep. Phylogenetic analysis based on the 16S rRNA gene sequence showed that strain LMO-1T belonged to genus Sphingomonas , with the highest sequence similarity to Sphingomonas formosensis CC-Nfb-2T (96.3 %), followed by Sphingomonas prati W18RDT (96.1 %), Sphingomonas arantia 6PT (96.0 %) and Sphingomonas montana W16RDT (95.9 %). The predominant polar lipids were phosphatidylethanolamine, sphingoglycolipid, phosphatidylglycerol and phosphatidylcholine.
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Li, Chongping, Qiliang Lai, Yuanyuan Fu, Shuangxi Chen, and Zongze Shao. "Galbibacter marinus sp. nov., isolated from deep-sea sediment." International Journal of Systematic and Evolutionary Microbiology 63, Pt_4 (2013): 1427–30. http://dx.doi.org/10.1099/ijs.0.044305-0.

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A taxonomic study was carried out on a novel bacterium, designated strain ck-I2-15T, which was isolated from deep-sea sediment collected from the South-west Indian Ocean Ridge. Cells of strain ck-I2-15T were Gram-reaction-negative, rod-shaped, non-motile, moderately halophilic and capable of denitrification. Growth was observed with 0–9 % (w/v) NaCl and at temperatures of 10–37 °C. The novel strain was unable to degrade gelatin. The dominant cellular fatty acids were iso-C15 : 0, iso-C17 : 0 3-OH and summed feature 9 (iso-C17 : 1ω9c and/or 10-methyl C16 : 0). The major respiratory quinone was
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Li, Yi, Xiao-Meng Sun, Jian Li, et al. "Marinomonas profundi sp. nov., isolated from deep seawater of the Mariana Trench." International Journal of Systematic and Evolutionary Microbiology 70, no. 11 (2020): 5747–52. http://dx.doi.org/10.1099/ijsem.0.004472.

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A Gram-stain-negative, aerobic, polarly flagellated, straight or curved rod-shaped bacterium, designated strain M1K-6T, was isolated from deep seawater samples collected from the Mariana Trench. The strain grew at −4 to 37 °C (optimum, 25–30 °C), at pH 5.5–10.0 (optimum, pH 7.0) and with 0.5–14.0 % (w/v) NaCl (optimum, 2.0 %). It did not reduce nitrate to nitrite nor hydrolyse gelatin or starch. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain M1K-6T was affiliated with the genus Marinomonas , sharing 93.1–97.0 % sequence similarity with the type strains of recogniz
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Lai, Qiliang, Nan Qiao, Changliang Wu, Fengqin Sun, Jun Yuan, and Zongze Shao. "Stappia indica sp. nov., isolated from deep seawater of the Indian Ocean." International Journal of Systematic and Evolutionary Microbiology 60, no. 4 (2010): 733–36. http://dx.doi.org/10.1099/ijs.0.013417-0.

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A taxonomic study was carried out on strain B106T, which was isolated from a polycyclic aromatic hydrocarbon-degrading consortium, enriched with deep seawater from the Indian Ocean. The isolate was Gram-negative, oxidase- and catalase-positive, rod-shaped and motile by means of one polar flagellum. Growth was observed at salinities of 0.5–11 % and at temperatures of 4–42 °C, and the strain was capable of nitrate reduction, but was unable to degrade Tween 80 or gelatin. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain B106T belonged to the genus Stappia, with a highe
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