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Journal articles on the topic 'DDAE'

Author: Grafiati

Published: 20 April 2024

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1

Lai, Po-Ting, Wei-Liang Lu, Ting-Rung Kuo, et al. "Using a Large Margin Context-Aware Convolutional Neural Network to Automatically Extract Disease-Disease Association from Literature: Comparative Analytic Study." JMIR Medical Informatics 7, no. 4 (2019): e14502. http://dx.doi.org/10.2196/14502.

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Background Research on disease-disease association (DDA), like comorbidity and complication, provides important insights into disease treatment and drug discovery, and a large body of the literature has been published in the field. However, using current search tools, it is not easy for researchers to retrieve information on the latest DDA findings. First, comorbidity and complication keywords pull up large numbers of PubMed studies. Second, disease is not highlighted in search results. Finally, DDA is not identified, as currently no disease-disease association extraction (DDAE) dataset or too

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Unger, Benjamin. "Discontinuity Propagation in Delay Differential-Algebraic Equations." Electronic Journal of Linear Algebra 34 (February 21, 2018): 582–601. http://dx.doi.org/10.13001/1081-3810.3759.

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The propagation of primary discontinuities in initial value problems for linear delay differential-algebraic equations (DDAEs) is discussed. Based on the (quasi-) Weierstra{\ss} form for regular matrix pencils, a complete characterization of the different propagation types is given and algebraic criteria in terms of the matrices are developed. The analysis, which is based on the method of steps, takes into account all possible inhomogeneities and history functions and thus serves as a worst-case scenario. Moreover, it reveals possible hidden delays in the DDAE and allows to study exponential s

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3

Azmat, A., I. Ali, W. Ariyanti, M. G. L. Putra, and T. Nadeem. "Environmental Noise Reduction based on Deep Denoising Autoencoder." Engineering, Technology & Applied Science Research 12, no. 6 (2022): 9532–35. http://dx.doi.org/10.48084/etasr.5239.

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Speech enhancement plays an important role in Automatic Speech Recognition (ASR) even though this task remains challenging in real-world scenarios of human-level performance. To cope with this challenge, an explicit denoising framework called Deep Denoising Autoencoder (DDAE) is introduced in this paper. The parameters of DDAE encoder and decoder are optimized based on the backpropagation criterion, where all denoising autoencoders are stacked up instead of recurrent connections. For better speech estimation in real and noisy environments, we include matched and mismatched noisy and clean pair

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Saad, Omar M., and Yangkang Chen. "Deep denoising autoencoder for seismic random noise attenuation." GEOPHYSICS 85, no. 4 (2020): V367—V376. http://dx.doi.org/10.1190/geo2019-0468.1.

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Attenuation of seismic random noise is considered an important processing step to enhance the signal-to-noise ratio of seismic data. A new approach is proposed to attenuate random noise based on a deep-denoising autoencoder (DDAE). In this approach, the time-series seismic data are used as an input for the DDAE. The DDAE encodes the input seismic data to multiple levels of abstraction, and then it decodes those levels to reconstruct the seismic signal without noise. The DDAE is pretrained in a supervised way using synthetic data; following this, the pretrained model is used to denoise the fiel

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Lazim, Raghad Yaseen, Zhu Yun, and Xiaojun Wu. "Improving Speech Quality for Hearing Aid Applications Based on Wiener Filter and Composite of Deep Denoising Autoencoders." Signals 1, no. 2 (2020): 138–56. http://dx.doi.org/10.3390/signals1020008.

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In hearing aid devices, speech enhancement techniques are a critical component to enable users with hearing loss to attain improved speech quality under noisy conditions. Recently, the deep denoising autoencoder (DDAE) was adopted successfully for recovering the desired speech from noisy observations. However, a single DDAE cannot extract contextual information sufficiently due to the poor generalization in an unknown signal-to-noise ratio (SNR), the local minima, and the fact that the enhanced output shows some residual noise and some level of discontinuity. In this paper, we propose a hybrid

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Driessen, W. L., R. A. G. de Graaff, F. J. Parlevliet, J. Reedijk, and R. M. de Vos. "Transition metal compounds of the tridentate pyrazole substituted amine ligand bis(2-(3,5-dimethyl-1-pyrazolyl)ethyl)ethylamine (ddae). X-ray structures of [Co(ddae)(NO3)2], [Cu(ddae)(NO3)(H2O)](NO3) and [Cu(ddae)(Cl)2]·C2H5OH." Inorganica Chimica Acta 216, no. 1-2 (1994): 43–49. http://dx.doi.org/10.1016/0020-1693(93)03707-h.

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Chen, Honghao, Xiangwen Kong, Xiangyu Zhang, Xin Zhao, and Kaiqi Huang. "DDAE: Towards Deep Dynamic Vision BERT Pretraining." Proceedings of the AAAI Conference on Artificial Intelligence 38, no. 2 (2024): 1037–45. http://dx.doi.org/10.1609/aaai.v38i2.27864.

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Recently, masked image modeling (MIM) has demonstrated promising prospects in self-supervised representation learning. However, existing MIM frameworks recover all masked patches equivalently, ignoring that the reconstruction difficulty of different patches can vary sharply due to their diverse distance from visible patches. In this paper, we propose a novel deep dynamic supervision to enable MIM methods to dynamically reconstruct patches with different degrees of difficulty at different pretraining phases and depths of the model. Our deep dynamic supervision helps to provide more locality ind

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Sulkhana, Sayyidah Irma, Fathul Niam, and Ahmad Saifudin. "Pengembangan Media DAKOTAR (Dakon Matematika Pintar) Materi Satuan Panjang dan Satuan Berat untuk Meningkatkan Keaktifan dan Kemampuan Berhitung Siswa Kelas IV di SDN Gogodeso 01." Patria Eduacational Journal (PEJ) 2, no. 2 (2022): 7–12. http://dx.doi.org/10.28926/pej.v2i2.376.

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Abstract: Learning media is an intermediary tool to convey messages or learning materials used dby dteachers/educators dto dstudents dso dthat dthey dcan dattract dstudents' dattention, dthoughts dand dinterests dto dparticipate din dthe dlearning dprocess. dBased don dinterviews dthat dresearchers dconducted dwith dfourth dgrade dteachers dat dSDN dGogodeso dd01, ddthey ddfound ddproblems, ddnamely dd(1) ddlack ddof ddvariety ddof ddlearning ddmedia dd(2) ddteachers ddstill dduse ddthe ddlecture ddmethod ddin ddthe ddlearning ddprocess. ddThe ddpurpose ddof ddthis dddevelopment ddresearch ddi

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Deshmukh, Venkatesh. "Approximate Stability Analysis and Computation of Solutions of Nonlinear Delay Differential Algebraic Equations with Time Periodic Coefficients." Journal of Vibration and Control 16, no. 7-8 (2010): 1235–60. http://dx.doi.org/10.1177/1077546309341137.

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Approximate stability analysis of nonlinear delay differential algebraic equations (DDAEs) with periodic coefficients is proposed with a geometric interpretation of evolution of the linearized system. Firstly, a numerical algorithm based on direct integration by expansion in terms of Chebyshev polynomials is derived for linear analysis. The proposed algorithm is shown to have deeper connections with and be computationally less cumbersome than the solution of the underlying semi-explicit system via a similarity transformation. The stability of time periodic DDAE systems is characterized by the

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Wei, Chengyan, and Shenxiang Wang. "Research on Improving the Executive Ability of University Administrators Based on Deep Learning." Computational and Mathematical Methods in Medicine 2022 (June 9, 2022): 1–10. http://dx.doi.org/10.1155/2022/6354801.

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Over the years, experts have focused their research on ways to increase the executive capacity of university administrators. This is because only by improving the quality of execution of college and university administrative personnel can they actively execute various policies and measures, fully exploit their subjective initiative, and ensure the educational reform of colleges and universities. Increasing the executive capacity of administrative staff can help colleges and universities manage more effectively. Therefore, in the development process of higher education institutions, it is neces

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Pañella, Anna, Josefina Pons, Jordi García-Antón, Xavier Solans, Mercè Font-Bardia, and Josep Ros. "Synthesis of New Palladium(II) Complexes Containing HemilabileN-(Alkylamino)pyrazole Ligands: Spectroscopic Analysis and Crystal Structure of [PdCl(ddae)]Cl·H2O {ddae = Bis[2-(3,5-dimethyl-1-pyrazolyl)ethyl]ethylamine}." European Journal of Inorganic Chemistry 2006, no. 8 (2006): 1678–85. http://dx.doi.org/10.1002/ejic.200501056.

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Bao, Fuli, and Chong Wang. "A Method for Evaluating the Quality of Mathematics Education Based on Artificial Neural Network." Computational and Mathematical Methods in Medicine 2022 (August 12, 2022): 1–11. http://dx.doi.org/10.1155/2022/6976654.

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Teaching quality evaluation (TQE) is an important link in the process of school teaching management. Evaluation indicators and teaching quality have a complicated and nonlinear connection that is influenced by several variables. Some of these drawbacks include too much subjectivity and unpredictability, difficulty in defining index weights, sluggish convergence, and weak computer capacity. The current assessment techniques and models have these issues as well. This research uses an ANN model to assess the quality of mathematics instruction at colleges and universities (CAU) in order to address

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Galambos, Jörg, Claudia Meuli-Simmen, Regula Schmid, Lisa S. Steinmann, and Werner Kempf. "Diffuse Dermal Angiomatosis of the Breast: A Distinct Entity in the Spectrum of Cutaneous Reactive Angiomatoses – Clinicopathologic Study of Two Cases and Comprehensive Review of the Literature." Case Reports in Dermatology 9, no. 3 (2017): 194–205. http://dx.doi.org/10.1159/000480721.

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Diffuse dermal angiomatosis (DDA) is a rare reactive angioproliferation in the skin and considered to be a subtype in the group of cutaneous reactive angiomatoses. DDA is clinically characterized by livedoid patches and plaques with tender ulceration. Its histologic features are a reactive diffuse proliferation of bland endothelial cells and pericytes within the dermis, forming small capillary vessels. Previously described cases of DDA most commonly involved the limbs and were associated with a wide spectrum of predisposing comorbidities, especially advanced atherosclerotic vascular disease an

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Al-Qudsy, Zainab N. Al, Zainab Mahmood Fadhil, Refed Adnan Jaleel, and Musaddak Maher Abdul Zahra. "Blockchain and 1D-CNN based IoTs for securing and classifying of PCG sound signal data." Fusion: Practice and Applications 12, no. 2 (2023): 28–41. http://dx.doi.org/10.54216/fpa.120203.

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The Internet of Things (IoTs) has accelerated with the introduction of powerful biomedical sensors, telemedicine services and population ageing are concerns that can be solved by smart healthcare systems. However, the security of medical signal data that collected from sensors of IoTs technology, while it is being transmitted over public channels has grown to be a serious problem that has limited the adoption of intelligent healthcare systems. This suggests using the technology of blockchain to create a safe and reliable heart sound signal (PCG) that can communicate with wireless body area net

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Stukel, M. R., V. J. Coles, M. T. Brooks, and R. R. Hood. "Top-down, bottom-up and physical controls on diatom-diazotroph assemblage growth in the Amazon River plume." Biogeosciences 11, no. 12 (2014): 3259–78. http://dx.doi.org/10.5194/bg-11-3259-2014.

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Abstract. The nutrient-rich waters of the Amazon River plume (ARP) support dense blooms of diatom-diazotroph assemblages (DDAs) that introduce large quantities of new nitrogen to the planktonic ecosystem and, unlike other nitrogen-fixers, are likely to directly fuel vertical carbon flux. To investigate the factors controlling DDA blooms, we develop a five phytoplankton (cyanobacteria, diatoms, unicellular microbial diazotrophs, DDAs, and Trichodesmium), two zooplankton model and embed it within a 1/6° resolution physical model of the tropical and subtropical Atlantic. The model generates reali

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Law, Brian K., Mary E. Law, Elham Yaaghubi, et al. "Abstract 6148: Disulfide isomerases AGR2, ERp44, and PDIA1 maintain death receptor 5 in an auto-inhibited, monomeric form." Cancer Research 83, no. 7_Supplement (2023): 6148. http://dx.doi.org/10.1158/1538-7445.am2023-6148.

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Abstract Previous studies indicated that compounds termed Disulfide bond Disrupting Agents (DDAs) exhibit anti-cancer activity that is associated with downregulation of EGFR/HER1, HER2, and HER3, and activation of Death Receptors 4 and 5 (DR4/5). DDA-induced HER1-3 downregulation is preceded by disulfide-mediated oligomerization. In contrast, DDA-mediated DR4/5 oligomerization results in DR5 upregulation, and activation of DR4/5 pro-apoptotic signaling through Caspases 8 and 3. However, the precise mechanisms by which altered disulfide bonding stabilizes and activates DR5 are unknown. A recent

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Law, Mary E., Zaafir M. Dulloo, Elham Yaaghubi, et al. "Abstract 552: Non-canonical disulfide isomerases are strongly selective, understudied targets for cancer therapy." Cancer Research 84, no. 6_Supplement (2024): 552. http://dx.doi.org/10.1158/1538-7445.am2024-552.

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Abstract A major challenge in cancer therapy is the identification of drug targets that are essential for cancer cells but not non-transformed cells. The Broad Institute’s Dependency Map (DepMap) evaluates whether knocking down or knocking out expression of specific genes is “strongly selective” against subsets of cancer cells, in contrast with genes that are “common essential.” Of the 22 human Protein Disulfide Isomerases (PDIs), only four, ERp44, TMX1, AGR2, and AGR3, were identified as strongly selective in the DepMap. Importantly, our team previously identified ERp44, AGR2, and AGR3 as tar

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Suratanee, Apichat, and Kitiporn Plaimas. "DDA: A Novel Network-Based Scoring Method to Identify Disease-Disease Associations." Bioinformatics and Biology Insights 9 (January 2015): BBI.S35237. http://dx.doi.org/10.4137/bbi.s35237.

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Categorizing human diseases provides higher efficiency and accuracy for disease diagnosis, prognosis, and treatment. Disease-disease association (DDA) is a precious information that indicates the large-scale structure of complex relationships of diseases. However, the number of known and reliable associations is very small. Therefore, identification of DDAs is a challenging task in systems biology and medicine. Here, we developed a novel network-based scoring algorithm called DDA to identify the relationships between diseases in a large-scale study. Our method is developed based on a random wa

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Yang, Jingmin, Shanghui Deng, Li Xu, and Wenjie Zhang. "Calibration-Free 3D Indoor Positioning Algorithms Based on DNN and DIFF." Sensors 22, no. 15 (2022): 5891. http://dx.doi.org/10.3390/s22155891.

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The heterogeneity of wireless receiving devices, co-channel interference, and multi-path effect make the received signal strength indication (RSSI) of Wi-Fi fluctuate greatly, which seriously degrades the RSSI-based positioning accuracy. Signal strength difference (DIFF), a calibration-free solution for handling the received signal strength variance between diverse devices, can effectively reduce the negative impact of signal fluctuation. However, DIFF also leads to the explosion of the RSSI data dimension, expanding the number of dimensions from m to Cm2, which reduces the positioning efficie

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Feng, Wenyan, and Fan Feng. "Research on the Multimodal Digital Teaching Quality Data Evaluation Model Based on Fuzzy BP Neural Network." Computational Intelligence and Neuroscience 2022 (June 11, 2022): 1–12. http://dx.doi.org/10.1155/2022/7893792.

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We propose in this paper a fuzzy BP neural network model and DDAE-SVR deep neural network model to analyze multimodal digital teaching, establish a multimodal digital teaching quality data evaluation model based on a fuzzy BP neural network, and optimize the initial weights and thresholds of BP neural network by using adaptive variation genetic algorithm. Since the BP neural network is highly dependent on the initial weights and points, the improved genetic algorithm is used to optimize the initial weights and thresholds of the BP neural network, reduce the time for the BP neural network to fi

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Mariano Silva, Luis Felipe, Ana Kleiber Pessoa Borges, and Janaina De Sousa Menezes. "ANÁLISE DA OCORRENCIA DE DOENÇAS DIARREICAS NO PERÍODO DE 2015 A 2020 EM PALMAS-TO." Revista de Patologia do Tocantins 8, no. 3 (2021): 120–24. http://dx.doi.org/10.20873/uft.2446-6492.2021v8n3p120.

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Introdução: As doenças diarreicas agudas (DDAs) são caracterizadas pelo aumento da frequência, quantidade de evacuações e pela diminuição da consistência fecal. as DDAs têm expressiva influência nas taxas de morbimortalidade em países subdesenvolvidos e em desenvolvimento, como o Brasil, tornando-se um problema de saúde pública. Esta pesquisa tem como objetivo analisar a ocorrência de doenças diarreicas na população do município de Palmas-TO entre os anos de 2015 a 2020. Método: Foi realizado um estudo descritivo com dados secundários, no município de Palmas-TO. O estudo foi realizado através

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Konopelchenko, B. G. "On the Deformation Theory of Structure Constants for Associative Algebras." Advances in Mathematical Physics 2010 (2010): 1–21. http://dx.doi.org/10.1155/2010/389091.

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An algebraic scheme for constructing deformations of structure constants for associative algebras generated by deformation driving algebras (DDAs) is discussed. An ideal of left divisors of zero plays a central role in this construction. Deformations of associative three-dimensional algebras with the DDA being a three-dimensional Lie algebra and their connection with integrable systems are studied.

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Zhang, Min, Chong-sheng Peng, and Xiao-bo Li. "In VivoandIn VitroMetabolites from the Main Diester and Monoester Diterpenoid Alkaloids in a Traditional Chinese Herb, theAconitumSpecies." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–23. http://dx.doi.org/10.1155/2015/252434.

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Diester diterpenoid alkaloids (DDAs), such as aconitine (AC), mesaconitine (MA), and hypaconitine (HA), are both pharmacologically active compounds and toxic ingredients in a traditional Chinese herb, theAconitumspecies. Many DDA metabolism studies have been performed to explore mechanisms for reducing toxicity in these compounds and inAconitumspecies extracts for safe clinical administration. In this review, we summarize recent progress on the metabolism of toxic AC, MA, and HA and corresponding monoester diterpenoid alkaloids (MDAs) in the gastrointestinal tract and liver in different animal

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Gao, Meng, Gabrielle Armin, and Keisuke Inomura. "Low-Ammonium Environment Increases the Nutrient Exchange between Diatom–Diazotroph Association Cells and Facilitates Photosynthesis and N2 Fixation—a Mechanistic Modeling Analysis." Cells 11, no. 18 (2022): 2911. http://dx.doi.org/10.3390/cells11182911.

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Diatom–diazotroph associations (DDAs) are one of the most important symbiotic dinitrogen (N2) fixing groups in the oligotrophic ocean. Despite their capability to fix N2, ammonium (NH4+) remains a key nitrogen (N) source for DDAs, and the effect of NH4+ on their metabolism remains elusive. Here, we developed a coarse-grained, cellular model of the DDA with NH4+ uptake and quantified how the level of extracellular NH4+ influences metabolism and nutrient exchange within the symbiosis. The model shows that, under a fixed growth rate, an increased NH4+ concentration may lower the required level of

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Psathas, Emmanouil D., Athanasios Katsargyris, Stella Lioudaki, Demetrios N. Moris, Mikes Doulaptsis, and Chris Klonaris. "Treatment paradigms for ductus arteriosus aneurysms in adults." Vascular 22, no. 4 (2013): 297–301. http://dx.doi.org/10.1177/1708538113495680.

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We report two symptomatic cases of ductus arteriosus aneurysm (DDA) in adults treated in our department over a 5-years period. One patient underwent an open off-pump surgical procedure, while the second one was treated with partial aortic arch debranching and endovascular stent-grafting. DDA in adults is an uncommon condition and can present with rupture, hoarseness or symptoms of airway obstruction. Although indications for intervention are not clearly established, most authors advocate that DDAs should be treated regardless of their size, to avoid the risk of rupture, while others reserve in

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Yang, H. H., F. C. Jin, and L. M. Wei. "The hydrogen bonding characteristic of (H2O)n (n=14-17)：quantum theory of atoms in molecules." Digest Journal of Nanomaterials and Biostructures 16, no. 4 (2021): 1401–9. http://dx.doi.org/10.15251/djnb.2021.164.1401.

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The hydrogen bonding characteristics of water clusters (H2O)n (n=14-17) are investigated by using Quantum Theory of Atoms in Molecules (QTAIM). The stabilities of the water clusters are related to the strength and number of hydrogen bonding. The strength of hydrogen bonding is primarily concerned with the characteristic of the donor molecule. The electron densities of bonding critical points of hydrogen bonding formed by DAA, DDAA and DDA molecule as hydrogen-donor (H-donor) are about 0.045 a.u., 0.035 a.u. and 0.025 a.u. respectively. The strength of hydrogen bonding formed by DAA as H-donor

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Kartheeswaran, Karpaga Priyaa, Arockia Xavier Annie Rayan, and Geetha Thekkumpurath Varrieth. "Enhanced disease-disease association with information enriched disease representation." Mathematical Biosciences and Engineering 20, no. 5 (2023): 8892–932. http://dx.doi.org/10.3934/mbe.2023391.

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<abstract> <sec><title>Objective</title><p>Quantification of disease-disease association (DDA) enables the understanding of disease relationships for discovering disease progression and finding comorbidity. For effective DDA strength calculation, there is a need to address the main challenge of integration of various biomedical aspects of DDA is to obtain an information rich disease representation. Materials and</p> </sec> <sec><title>Methods</title><p>An enhanced and integrated DDA framework is developed that integrates enriche

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Poruchynsky, Marianne S., Edina Komlodi-Pasztor, Shana Trostel, et al. "Microtubule-targeting agents augment the toxicity of DNA-damaging agents by disrupting intracellular trafficking of DNA repair proteins." Proceedings of the National Academy of Sciences 112, no. 5 (2015): 1571–76. http://dx.doi.org/10.1073/pnas.1416418112.

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The paradigm that microtubule-targeting agents (MTAs) cause cell death via mitotic arrest applies to rapidly dividing cells but cannot explain MTA activity in slowly growing human cancers. Many preferred cancer regimens combine a MTA with a DNA-damaging agent (DDA). We hypothesized that MTAs synergize with DDAs by interfering with trafficking of DNA repair proteins on interphase microtubules. We investigated nine proteins involved in DNA repair: ATM, ATR, DNA-PK, Rad50, Mre11, p95/NBS1, p53, 53BP1, and p63. The proteins were sequestered in the cytoplasm by vincristine and paclitaxel but not by

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Li, Manqing, Elaine Kao, Dane Malone, Xia Gao, Jean Y. J. Wang, and Michael David. "Human intrinsic immunity factor SLFN11 promotes cell death upon DNA damages through cleavage of distinct type II tRNAs and inhibition of proteins syntheses related to DNA damage responses and repairs." Journal of Immunology 202, no. 1_Supplement (2019): 194.20. http://dx.doi.org/10.4049/jimmunol.202.supp.194.20.

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Abstract Previously we showed that as an intrinsic immunity factor, human SLFN11 inhibits HIV viral proteins syntheses by modulating tRNAs abundances and exploiting the biased codon usage of the virus. Transcriptome analysis in vast collection of cancer cell lines revealed that SLFN11 is the only gene whose expression significantly sensitizes tumor cells to DNA damaging agents (DDAs). We hereby report that SLFN11 preferentially inhibits translation of genes involved in DNA damage response and repair, including ATR and ATM, upon DDAs treatment based on their distinct codon usages without disrup

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Zhang, Saining, Yuhang Zhang, Ye Zhang, Yufei Wang, and Zhigang Song. "A Dual-Direction Attention Mixed Feature Network for Facial Expression Recognition." Electronics 12, no. 17 (2023): 3595. http://dx.doi.org/10.3390/electronics12173595.

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In recent years, facial expression recognition (FER) has garnered significant attention within the realm of computer vision research. This paper presents an innovative network called the Dual-Direction Attention Mixed Feature Network (DDAMFN) specifically designed for FER, boasting both robustness and lightweight characteristics. The network architecture comprises two primary components: the Mixed Feature Network (MFN) serving as the backbone, and the Dual-Direction Attention Network (DDAN) functioning as the head. To enhance the network’s capability in the MFN, resilient features are extracte

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Jabir, T., V. Dhanya, Y. Jesmi, et al. "Occurrence and Distribution of a Diatom-Diazotrophic Cyanobacteria Association during a Trichodesmium Bloom in the Southeastern Arabian Sea." International Journal of Oceanography 2013 (August 6, 2013): 1–6. http://dx.doi.org/10.1155/2013/350594.

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Symbiotic diatom-diazotrophic cyanobacteria association (DDA) of Rhizosolenia hebetata and Rhizosolenia formosa with endosymbiotic cyanobacteria Richelia intracellularis was noticed and documented for the first time during a bloom of the cyanobacterium Trichodesmium erythraeum in the oligotrophic shelf waters along Kochi and Mangalore transects, southeastern Arabian Sea (SEAS), during spring intermonsoon (April 2012). Although the host is frequently seen, the symbiont is rarely reported in the Indian EEZ. The presence of nitrogen-fixing symbiotic association of Rhizosolenia-Richelia along with

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Bale, Nicole J., Tracy A. Villareal, Ellen C. Hopmans, et al. "C<sub>5</sub> glycolipids of heterocystous cyanobacteria track symbiont abundance in the diatom <i>Hemiaulus hauckii</i> across the tropical North Atlantic." Biogeosciences 15, no. 4 (2018): 1229–41. http://dx.doi.org/10.5194/bg-15-1229-2018.

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Abstract. Diatom–diazotroph associations (DDAs) include marine heterocystous cyanobacteria found as exosymbionts and endosymbionts in multiple diatom species. Heterocysts are the site of N2 fixation and have thickened cell walls containing unique heterocyst glycolipids which maintain a low oxygen environment within the heterocyst. The endosymbiotic cyanobacterium Richelia intracellularis found in species of the diatom genus Hemiaulus and Rhizosolenia makes heterocyst glycolipids (HGs) which are composed of C30 and C32 diols and triols with pentose (C5) moieties that are distinct from limnetic

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Potvin, Corey K., and Louis J. Wicker. "Comparison between Dual-Doppler and EnKF Storm-Scale Wind Analyses: Observing System Simulation Experiments with a Supercell Thunderstorm." Monthly Weather Review 140, no. 12 (2012): 3972–91. http://dx.doi.org/10.1175/mwr-d-12-00044.1.

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Abstract Kinematical analyses of mobile radar observations are critical to advancing the understanding of supercell thunderstorms. Maximizing the accuracy of these and subsequent dynamical analyses, and appropriately characterizing the uncertainty in ensuing conclusions about storm structure and processes, requires thorough knowledge of the typical errors obtained using different retrieval techniques. This study adopts an observing system simulation experiment (OSSE) framework to explore the errors obtained from ensemble Kalman filter (EnKF) assimilation versus dual-Doppler analysis (DDA) of s

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Willis, Sophie E., Claudia Winkler, Martine P. Roudier, et al. "Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response." British Journal of Cancer 125, no. 12 (2021): 1666–76. http://dx.doi.org/10.1038/s41416-021-01560-1.

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Abstract Background The absence of the putative DNA/RNA helicase Schlafen11 (SLFN11) is thought to cause resistance to DNA-damaging agents (DDAs) and PARP inhibitors. Methods We developed and validated a clinically applicable SLFN11 immunohistochemistry assay and retrospectively correlated SLFN11 tumour levels to patient outcome to the standard of care therapies and olaparib maintenance. Results High SLFN11 associated with improved prognosis to the first-line treatment with DDAs platinum-plus-etoposide in SCLC patients, but was not strongly linked to paclitaxel–platinum response in ovarian can

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Hollenhorst, Marie A., Jon Clardy, and Christopher T. Walsh. "The ATP-Dependent Amide Ligases DdaG and DdaF Assemble the Fumaramoyl-Dipeptide Scaffold of the Dapdiamide Antibiotics." Biochemistry 49, no. 29 (2010): 6296. http://dx.doi.org/10.1021/bi101016e.

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Hollenhorst, Marie A., Jon Clardy, and Christopher T. Walsh. "The ATP-Dependent Amide Ligases DdaG and DdaF Assemble the Fumaramoyl-Dipeptide Scaffold of the Dapdiamide Antibiotics." Biochemistry 48, no. 43 (2009): 10467–72. http://dx.doi.org/10.1021/bi9013165.

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Dantoni, Patrícia, Ana Clara B. Rodrigues, Margareth Mie N. Matsuda, and Nina Coichev. "Effect of some surfactants on the chemiluminescent reactions of bis(2,4,6-trichlorophenyl)oxalate and bis(2-nitrophenyl)oxalate with hydrogen peroxide." Canadian Journal of Chemistry 90, no. 6 (2012): 534–41. http://dx.doi.org/10.1139/v2012-025.

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The chemiluminescent reactions of bis(2,4,6-trichlorophenyl)oxalate (TCPO) and bis(2-nitrophenyl)oxalate (2-NPO) with hydrogen peroxide in acetonitrile/water micellar systems (anionic, cationic, and non-ionic) and γ-cyclodextrin were studied in the presence of fluoranthene or 9,10-diphenylanthracene, imidazole, and two buffer solutions, HTRIS+/TRIS and H2PO4–/HPO42–. The relative chemiluminenscence (CL) intensity is higher in the presence of the cationic (DDAB, CTAC, DODAC, and OTAC), anionic (SDS), and non-ionic (Tween 80) surfactants. In the presence of some non-ionic surfactants (Brij 35, B

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Hollenhorst, Marie A., Jon Clardy, and Christopher T. Walsh. "Correction to The ATP-Dependent Amide Ligases DdaG and DdaF Assemble the Fumaramoyl-Dipeptide Scaffold of the Dapdiamide Antibiotics." Biochemistry 49, no. 8 (2010): 1808. http://dx.doi.org/10.1021/bi100095k.

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Fu, Xiaodan, Lin Zhu, Li Li, Tan Zhang, Meng Li, and Haijin Mou. "Eco-friendly preparation of chitooligosaccharides with different degrees of deacetylation from shrimp shell waste and their effects on the germination of wheat seeds." Marine Life Science & Technology 1, no. 1 (2019): 95–103. http://dx.doi.org/10.1007/s42995-019-00012-3.

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Abstract Production of chitosan and its derivatives by traditional methods involves the excessive use of a reaction solution comprised of sodium hydroxide and hydrochloric acid. Waste water resulting from this process has limited the application of chitosan as a fertilizer as the process causes serious environmental pollution. Specifically, the resulting waste water contains high levels of dissolved nitrogen and minerals from shrimp shells. In this study, an eco-friendly method was established to produce chitooligosaccharides (COS) with different degrees of deacetylation (DDAs) from shrimp she

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LEIPER, James M., Joanne SANTA MARIA, Ann CHUBB, et al. "Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases." Biochemical Journal 343, no. 1 (1999): 209–14. http://dx.doi.org/10.1042/bj3430209.

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Methylarginines inhibit nitric oxide synthases (NOS). Cellular concentrations of methylarginines are determined in part by the activity of dimethylarginine dimethylaminohydrolase (DDAH; EC 3.5.3.18). We have cloned human DDAH and identified and expressed a second novel DDAH isoform (DDAH I and II respectively). DDAH I predominates in tissues that express neuronal NOS. DDAH II predominates in tissues expressing endothelial NOS. These results strengthen the hypothesis that methylarginine concentration is actively regulated and identify molecular targets for the tissue and cell-specific regulatio

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Duru, Metin. "Demir Dikeni (Tribulus terrestris) Saponin Ekstraktının Yumurtacı Tavuklarda Performans, Yumurta Kalite Kriterleri ve Bazı Kan Parametreleri Üzerine Etkileri." Turkish Journal of Agriculture - Food Science and Technology 12, no. 3 (2024): 423–29. http://dx.doi.org/10.24925/turjaf.v12i3.423-429.6684.

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Bu çalışma, karma yeme demir dikeni bitkisi (Tribulus terrestris) saponin ekstraktı (DDSE) ilavesinin yumurtacı tavuklarda performans, iç-dış yumurta kalite kriterleri, yumurta kolesterol düzeyleri ve bazı kan serum parametreleri üzerine etkisini incelemek amacıyla yürütülmüştür. Araştırma grupları ticari yumurtacı karma yemine 0 (kontrol); 1 g DDSE, 2 g DDSE, 4 g DDSE ve 8 g DDSE eklenerek 5 gruptan oluşturulmuştur. Toplam 80 adet yumurtacı tavuk her bir grupta 16 hayvan olacak şekilde gruplara rastgele dağıtılmıştır. Araştırma sonuçlarına göre; kontrol grubu hariç diğer deneme gruplarına gör

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Drmić, Z., M. Čačija, H. Virić Gašparić, D. Lemić, and R. Bažok. "Phenology of the sugar beet weevil, Bothynoderes punctiventris Germar (Coleoptera: Curculionidae), in Croatia." Bulletin of Entomological Research 109, no. 4 (2018): 518–27. http://dx.doi.org/10.1017/s000748531800086x.

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AbstractThe sugar beet weevil (SBW), Bothynoderes punctiventris Germar, 1824, is a significant pest in most of Eastern Europe. Here, the SBW is described and its seasonal activity characterized, in terms of its different developmental stages in relation to Julian days (JDs), degree-day accumulations (DDAs), and precipitation, as a key to improving monitoring and forecasting of the pest. The phenology and population characteristics of SBW were investigated in sugar beet fields in eastern Croatia over a 4-year period (2012–2015). By using the degree-day model (lower development threshold of 5°C,

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Chen, YingJie, Yunfang Li, Ping Zhang, et al. "Dimethylarginine dimethylaminohydrolase and endothelial dysfunction in failing hearts." American Journal of Physiology-Heart and Circulatory Physiology 289, no. 5 (2005): H2212—H2219. http://dx.doi.org/10.1152/ajpheart.00224.2005.

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Congestive heart failure (CHF) is associated with impaired endothelium-dependent nitric oxide (NO)-mediated vasodilation (endothelial dysfunction). We hypothesized that coronary endothelial dysfunction in CHF may be due in part to decreased dimethylarginine dimethylaminohydrolase (DDAH), the enzyme that degrades endogenous inhibitors of NO synthase (NOS), including asymmetric dimethylarginine. Coronary blood flow and the endothelium-dependent vasodilator response to acetylcholine were studied in dogs in which CHF was produced by rapid ventricular pacing for 4 wk. Coronary flow and myocardial O

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Lin, Heng-Huei, Tzong-Shyuan Lee, Shing-Jong Lin, Yi-Chen Yeh, Tse-Min Lu, and Chiao-Po Hsu. "DDAH-2 alleviates contrast medium iopromide-induced acute kidney injury through nitric oxide synthase." Clinical Science 133, no. 23 (2019): 2361–78. http://dx.doi.org/10.1042/cs20190455.

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Abstract Background: Contrast medium-induced acute kidney injury (CI-AKI) is one of the most common causes of hospital-acquired acute renal failure. However, the pathogenesis of CI-AKI remains unclear. Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase (NOS) inhibitor that is largely metabolised by dimethylarginine dimethylaminohydroxylase (DDAH) in humans. Two isoforms of DDAH exist, namely, DDAH-1 and DDAH-2. In the present study, we examined whether the DDAH-2/ADMA/NOS pathway is involved in the pathogenesis of CI-AKI. Methods and Results: Exposure to the contrast med

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Palm, Fredrik, Maristela L. Onozato, Zaiming Luo, and Christopher S. Wilcox. "Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems." American Journal of Physiology-Heart and Circulatory Physiology 293, no. 6 (2007): H3227—H3245. http://dx.doi.org/10.1152/ajpheart.00998.2007.

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Asymmetric ( NG, NG)-dimethylarginine (ADMA) inhibits nitric oxide (NO) synthases (NOS). ADMA is a risk factor for endothelial dysfunction, cardiovascular mortality, and progression of chronic kidney disease. Two isoforms of dimethylarginine dimethylaminohydrolase (DDAH) metabolize ADMA. DDAH-1 is the predominant isoform in the proximal tubules of the kidney and in the liver. These organs extract ADMA from the circulation. DDAH-2 is the predominant isoform in the vasculature, where it is found in endothelial cells adjacent to the cell membrane and in intracellular vesicles and in vascular smoo

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Wetzel, Michael D., Ting Gao, Kristen Stanley, Timothy K. Cooper, Sidney M. Morris, and Alaa S. Awad. "Enhancing kidney DDAH-1 expression by adenovirus delivery reduces ADMA and ameliorates diabetic nephropathy." American Journal of Physiology-Renal Physiology 318, no. 2 (2020): F509—F517. http://dx.doi.org/10.1152/ajprenal.00518.2019.

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Endothelial dysfunction, characterized by reduced bioavailability of nitric oxide and increased oxidative stress, is a hallmark characteristic in diabetes and diabetic nephropathy (DN). High levels of asymmetric dimethylarginine (ADMA) are observed in several diseases including DN and are a strong prognostic marker for cardiovascular events in patients with diabetes and end-stage renal disease. ADMA, an endogenous endothelial nitric oxide synthase (NOS3) inhibitor, is selectively metabolized by dimethylarginine dimethylaminohydrolase (DDAH). Low DDAH levels have been associated with cardiac an

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Tezel, U., S. G. Pavlostathis, and J. A. Pierson. "Effect of didecyl dimethyl ammonium chloride on nitrate reduction in a mixed methanogenic culture." Water Science and Technology 57, no. 4 (2008): 541–46. http://dx.doi.org/10.2166/wst.2008.068.

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The effect of the quaternary ammonium compound, didecyl dimethyl ammonium chloride (DDAC), on nitrate reduction was investigated at concentrations up to 100 mg/L in a batch assay using a mixed, mesophilic (35°C) methanogenic culture. Glucose was used as the carbon and energy source and the initial nitrate concentration was 70 mg N/L. Dissimilatory nitrate reduction to ammonia (DNRA) and to dinitrogen (denitrification) were observed at DDAC concentrations up to 25 mg/L. At and above 50 mg DDAC/L, DNRA was inhibited and denitrification was incomplete resulting in accumulation of nitrous oxide. A

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Yang, Jeong-Sun, Sung-Bong Choi, Sang-Yong Park, and Sung-Bae Lee. "Analysis of didecydimethylammonium chloride (DDAC) aerosol in inhalation chamber." Analytical Science and Technology 25, no. 5 (2012): 307–12. http://dx.doi.org/10.5806/ast.2012.25.5.307.

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Shane, Hillary L., Ewa Lukomska, and Stacey E. Anderson. "Type 2 innate lymphoid cells contribute to a mixed-type allergic response following topical exposure to the quaternary ammonium compound didecyldimethylammonium chloride." Journal of Immunology 200, no. 1_Supplement (2018): 104.9. http://dx.doi.org/10.4049/jimmunol.200.supp.104.9.

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Abstract Didecyldimethylammonium chloride (DDAC) is an antimicrobial dialkyl-quaternary ammonium compound used in numerous industrial and commercial products. Clinical and animal data suggest that DDAC exposure elicits multiple types of hypersensitivity reactions. To examine the immunological mechanism behind this mixed type response and the potential involvement of ILCs, we assessed early immune responses in the skin following dermal DDAC exposure (0.25% and 0.5%) in a BALB/c murine model. DDAC exposure resulted in a rapid and dramatic increase in the Th2-skewing and ILC2 activating cytokine

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Zhang, Jing, Sa Ma, Wenchang Wang, and Zhidong Chen. "Electrochemical Sensing of Bisphenol A by a Didodecyldimethylammonium Bromide-Modified Expanded Graphite Paste Electrode." Journal of AOAC INTERNATIONAL 99, no. 4 (2016): 1066–72. http://dx.doi.org/10.5740/jaoacint.16-0072.

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Abstract An electrochemical and sensitive sensing of 2,2-bis(4-hydroxyphenyl) propane [bisphenol A (BPA)] was developed based on a didodecyldimethylammonium bromide-modified expanded graphite paste electrode (DDAB-EGPE). The DDAB-EGPE was prepared by suspending an EGPE in a DDAB aqueous solution, and allowing the DDAB to form a hydrophobic film on the expanded graphite surface. Compared with the EGPE, the DDAB-EGPE showed improved electrochemical response of BPA because of the preconcentration of BPA in DDAB via hydrophobic interaction. Due to the electrocatalytic activity of BPA, a sensor for

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