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Published: 26 July 2024

Last updated: 27 July 2024

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1

CHMIELEWSKI, REVIS A., JOAN R. BECK, and DAVID E. SWAYNE. "Thermal Inactivation of Avian Influenza Virus and Newcastle Disease Virus in a Fat-Free Egg Product." Journal of Food Protection 74, no. 7 (July 1, 2011): 1161–68. http://dx.doi.org/10.4315/0362-028x.jfp-10-415.

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High-pathogenicity avian influenza (HPAI) virus, low-pathogenicity avian influenza (LPAI) virus, virulent Newcastle disease virus (vNDV) and low-virulent Newcastle disease virus (lNDV) can be present on the eggshell surface, and HPAI viruses and vNDV can be present in the internal contents of chicken eggs laid by infected hens. With the increase in global trade, egg products could present potential biosecurity problems and affect international trade in liquid and dried egg products. Therefore, the generation of survival curves to determine decimal reduction times (DT -values) and change in heat resistance of the viruses (zD-value) within fat-free egg product could provide valuable information for development of risk reduction strategies. Thermal inactivation studies using A/chicken/Pennsylvania/1370/83 (H5N2) HPAI virus resulted in D55-, D56-, D56.7-, D57-, D58-, and D59-values of 18.6, 8.5, 3.6, 2.5, 0.4, and 0.4 min, respectively. The zD-value was 4.4°C. LPAI virus A/chicken/New York/13142/94 (H7N2) had D55-, D56.7-, D57-, D58-, D59-, and D60-values of 2.9, 1.4, 0.8, 0.7, 0.7, and 0.5 min, respectively, and a z-value of 0.4°C. vNDV avian paramyxoviruses of serotype 1 (AMPV-1)/chicken/California/212676/2002 had D55-, D56-, D56.7-, D57-, D58-, and D59-values of 12.4, 9.3, 6.2, 5, 3.7, and 1.7 min, respectively. The zD-value was 4.7°C. lNDV AMPV-1/chicken/United States/B1/1948 had D55-, D57-, D58-, D59-, D61-, and D63-values of 5.3, 2.2, 1.1, 0.55, 0.19, and 0.17 min, respectively, and a zD-value of 1.0°C. Use of these data in developing egg pasteurization standards for AI and NDV-infected countries should allow safer trade in liquid egg products.

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2

Cho, Hwa Jin, Young Earl Choi, Eun Song Song, Young Kuk Cho, and Jae Sook Ma. "Procalcitonin Levels in Patients with Complete and Incomplete Kawasaki Disease." Disease Markers 35 (2013): 505–11. http://dx.doi.org/10.1155/2013/265051.

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Incomplete Kawasaki disease (iKD) is considered to be a less complete form of Kawasaki disease (cKD), and several differences in the laboratory presentations of iKD and cKD have been noted. We investigated serum procalcitonin levels in patients with iKD, cKD, and other febrile diseases (a control group). Seventy-seven patients with cKD, 24 with iKD, and 41 controls admitted to our hospital from November 2009 to November 2011 were enrolled in the present study. We obtained four measurements of serum procalcitonin levels and those of other inflammatory markers from each patient. Samples were taken for analysis on the day of diagnosis (thus before treatment commenced; D0) and 2 (D2), 14 (D14), and 56 days (D56) after intravenous immunoglobulin infusion. We obtained control group data at D0. The mean D0 serum procalcitonin levels of cKD patients (0.71±1.36 ng/mL) and controls (0.67±1.06 ng/mL) were significantly higher than those of iKD patients (0.26±0.26 ng/mL) (P=0.014andP=0.041, resp.). No significant difference in mean procalcitonin level was evident among groups at any subsequent time. In conclusion, the serum procalcitonin level of patients with acute-stage cKD was significantly higher than that of iKD patients.

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3

Braun, Thorsten, Emmanuel Raffoux, Thomas Prebet, Sabine Brechignac, Aspasia Stamatoullas, Francois Dreyfus, Zehaira Hebibi, et al. "Low-Dose Clofarabine Has Significant Activity in High-Risk Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia Post-MDS (sAML) After Azacitidine (AZA) Failure: Interim Results of the GFM Clo08 Dose Escalating Phase I/II Study (NCT0106325)." Blood 118, no. 21 (November 18, 2011): 609. http://dx.doi.org/10.1182/blood.v118.21.609.609.

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Abstract Abstract 609 Background: Clofarabine (CLO) alone has shown antileukemic activity in MDS and AML, including sAML, at doses ranging from 15 to 40 mg/m2, although with significant myelosuppression and toxicity. Patients with high-risk MDS or sAML who failed AZA have a median OS of only 5 months (Prébet, JCO, online), and no established drug therapy is available for such patients. In this Phase I/II dose escalating study (NCT0106325), we explored safety and activity of CLO at lower dosing levels (DLs), in such patients. Methods: A standard IV, D1-5 and an extended D1, 3, 5, 8 and 10, administration schedules were studied in parallel, using a standard 3+3 design. Three DLs (CLO 5, 7.5 and 10 mg/m2, daily) were planned. Dose limiting toxicities (DLTs) were defined as any grade >3 non-hematological toxicity, excluding bleeding, infections or febrile neutropenia, or as any delayed cytopenias past D56, defined here as blood counts less than 50% of baseline counts. Responses were evaluated according to IWG 2006 MDS criteria or AML IWG criteria after courses 1 and 2, administered within 56 days. Patients in CR/PR after course 1 could receive up to 7 maintenance courses with only 3 daily infusions at same dosing. Patients in CR/PR or with stable disease after course 2 could receive up to 6 maintenance courses. If DLTs after course 1 were observed in less than 1 of 3 or 2 of 6 patients, dose escalation was permitted. If 2 or more DLTs were observed after course 1, exploration of lower intermediate DLs was planned. Patients with de novo MDS or sAML who failed at least 6 courses of AZA were eligible, if not candidates to intensive chemotherapy. Exclusion criteria included renal dysfunction (MDRD<50 ml/mn), bilirubin>1.5 ULN, liver function tests >2.5 ULN, ECOG score >2, and uncontrolled infection. Patients: Between November 2009 and July 2011, 19 Patients (10F, 9M) were enrolled, at DL1 (5 mg/m2, N=9) and DL2 (7.5 mg/m2, N=10), Median age was 72 years (62-90), WHO diagnosis were: RAEB 1 (N=1), RAEB 2 (N=8), sAML (N=10), including 7 patients with <30% marrow blasts). Cytogenetics was normal in 4 (3 RAEB, 1 AML), complex or with abn chr. 7 in 11 (8 sAML, 3 RAEB), and inv3, +8, 5q and 11q, del9q in 4 patients. Median duration of MDS phase, before entry, was 20 months (9-161). Responses to prior treatment with AZA included 6 CR, 2 marrow CR (mCR) and 4 stable with HI-E, 6 failures and 1 stable w/o HI, after a median number of AZA cycles of 10 (6-34), 11 (6-26) and 6 (6-8) respectively. Eleven patients had only received AZA and eight AZA and 1 to 3 other treatment lines, excluding growth factors. Results: (Table 1) All patients were evaluable for DLTs and response after one cycle. In the D1-5 cohort: one DL1 patient was classified as failure and non-hematological DLT (due to likely unrelated sudden death on D55, before evaluation), and one DL2 patient with mCR as DLT, due to prolonged thrombocytopenia beyond D56. One sAML patient was classified as failure due to early death linked to sepsis, but not as DLT per protocol. In the D1-10 cohort, no DLT was observed after cycle 1. Fifteen patients were eligible for an identical second course, as 2 patients had early death and 2 CR/PR. Twelve patients received a second course, with only 1/8 evaluable for response after course 2, improving response. This patient with mCR obtained durable HI-E and P after course 2. No significant liver or renal toxicity was observed in both cohorts. Seven patients were hospitalized after first course for fever or bleeding (3/9 in DL1/5mg/m2 and 4/10 in DL2/7.5mg/m2 cohorts). Overall, 6 of the 19 patients (32%) had a response after a single course including 2CR/PR and 4 of the 6 responses were seen at the 7.5 mg/m2 dose level. Conclusion: In this dose escalating study in MDS or sAML patients who had failed azacitidine, low-dose clofarabine had significant activity and was administered as an outpatient therapy in most, although hospitalization due to myelosuppression was frequent, even at this low dosing. The extended alternate day (D1-10) schedule may be better tolerated and at least as efficient as the standard D1-5 schedule, although a larger number of patients is required to conclude. Dose escalation in the trial is continuing. Disclosures: Off Label Use: low dose Clofarabine in MDS after AZA failure. Vey:GENZYME: Honoraria. Dombret:GENZYME: Honoraria. Fenaux:GENZYME: Honoraria. Gardin:GENZYME: Honoraria, Research Funding.

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4

Silva, Italo Rômulo Costa da, and Antonia Dalva França Carvalho. "As gerações da Educação a Distância: olhares sobre a avaliação." Conjecturas 22, no. 3 (March 25, 2022): 507–27. http://dx.doi.org/10.53660/conj-796-d16.

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A Educação a Distância (EaD) dos tempos hodiernos é fruto de mudanças ocorridas ao longo dos anos. Não obstante do cenário convencional de ensino presencial, a modalidade à distância sempre lidou com todos os elementos do processo educativo como a didática, currículo, e avaliação. Neste contexto, a discussão aqui empreendida incide o binômio avaliação-EaD sob duas perspectivas. A primeira consiste na retomada da história da Educação a Distância. E a segunda em evidenciar as diferentes práticas avaliativas decorrentes de cada formato que a educação a distância assumiu desde sua primeira manifestação até os dias atuais. A reflexão se ancora em uma pesquisa qualitativa de cunho bibliográfico, sendo as análises teóricas apoiada nas ideias Barros (2003), Gomes (2003), Moore e Kearsley (2007), Garcia (2013), Silva (2013) para historicizarmos a percurso da EaD, e na interseção com a avaliação nos apoiamos sobretudo nos escritos de Vasconsellos (2005) e Luckesi (2013). Desse diálogo depreendemos que assim como ocorreram mudanças estruturais e pedagógicas nas gerações da EaD, tais modificações também fomentaram possibilidades distintas de avaliar o processo de ensino e aprendizagem.

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5

Otto, William R., Daryl M. Lamson, Gabriel Gonzalez, Geoffrey A. Weinberg, Nicole D. Pecora, Brian T. Fisher, Kirsten St. George, and Adriana E. Kajon. "Fatal Neonatal Sepsis Associated with Human Adenovirus Type 56 Infection: Genomic Analysis of Three Recent Cases Detected in the United States." Viruses 13, no. 6 (June 9, 2021): 1105. http://dx.doi.org/10.3390/v13061105.

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Background: Human adenovirus (HAdV)-D56 was first described in 2011 by genomics analysis of a strain isolated in France in 2008 from a fatal case of neonatal infection. Since then, it has been reported in cases of keratoconjunctivitis and male urethritis. Three epidemiologically unrelated fatal cases of neonatal sepsis associated with infection by HAdV-D strains with a similar genetic makeup were documented in the United States between 2014 and 2020. Methods: Whole genome sequences were obtained for the isolated strains, and genomics analyses were conducted to compare them to phylogenetically related HAdV-D genomic sequences available in GenBank. Results: The three new US strains were indistinguishable by in silico restriction enzyme analysis. Their genome sequences were 99.9% identical to one another and to the prototype strain isolated in 2008 from a similar context of disease. The phylogenetic reconstruction revealed a highly supported clustering of all HAdV-D56 strains isolated in various countries since 1982. Our comparison to serologically intermediate strains 15/H9 described in the literature indicated that HAdV-D56-like viruses have circulated worldwide since the late 1950s. Conclusion: As with other HAdV-D genotypes with the ability to infect ocular and genital mucosae, the risk of severe prenatal or perinatal HAdV-D56 infection must be considered.

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6

Sadok, Hicham. "The Effect of Exchange Rates on Trade Balance: An Empirical Study of Morocco." Journal of Business and Economics Review (JBER) Vol.3(1) Jan-Mar 2018 3, no. 1 (February 13, 2018): 01–10. http://dx.doi.org/10.35609/jber.2018.3.1(1).

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Objective - This paper aims to examine the relationship between exchange rates and trade balance in Morocco, to investigate whether the Marshall-Lerner condition and J-curve exist. Methodology/Technique - This paper attempts to identify the relationship between the real exchange rate and trade balance in Morocco between 2000 an 2015. Findings - Historically, exchange rates have had a strong impact on foreign trade in Morocco. Novelty - This study concludes that the fluctuation of exchange rates has no notable impact on the rate of foreign trade. Type of Paper: Empirical. Keywords: Exchange Rates; Trade Balance; Exports; Imports; Morocco. JEL Classification: D51, D59.

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7

Fielding, Adele K., Georgina Buck, Hillard M. Lazarus, Mark R. Litzow, Selina Luger, David I. Marks, Andrew McMillan, et al. "Imatinib Significantly Enhances Long-Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia; Final Results of the UKALLXII/ECOG2993 Trial." Blood 116, no. 21 (November 19, 2010): 169. http://dx.doi.org/10.1182/blood.v116.21.169.169.

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Abstract Abstract 169 The Philadelphia positive (Ph+) arm of the international adult acute lymphoblastic leukaemia (ALL) trial UKALL12/ECOG2993 opened in 1993 and is the largest single study of patients with Ph+ ALL, with a total of 441 participants. The first cohort of study patients was treated prior to Imatinib (N=266 “Pre Imatinib“) with 2 phases of induction therapy given over 2 months followed by matched sibling or unrelated donor myeloablative allogeneic haematopoietic stem cell transplant (alloHSCT) whenever possible. The treatment protocol and outcome for these patients has been published (Fielding et al, Blood 2009). Beginning March 2003, a second cohort of study patients had Imatinib 600mg daily added, as a consolidation block after the second induction chemotherapy, (N=86, “Late Imatinib”). From late 2005, a final cohort within the trial were given Imatinib earlier, in conjunction with the second phase of induction (N=89, “Early Imatinib”). Patients in both Imatinib cohorts resumed the drug for a further 2 years following alloHSCT, if tolerated. If alloHSCT was not possible, Imatinib was permitted for 2 years, with maintenance. The trial closed to recruitment in December 2006 (USA) and October 2008 (UK). All except 8 patients have now completed therapy. An earlier analysis of these data did not indicate a clear long-term advantage to receiving Imatinib. We now report 3-year follow-up, which shows large outcome differences between the 3 groups. There were no pre-existing differences between the 3 cohorts in terms of gender, presenting white blood cell counts and presence of central nervous system disease at diagnosis. However, the Pre-Imatinib cohort was younger than the two Imatinib cohorts, due to an increase in the upper age limit for study entry. Percentage complete remission (CR) rates and survival of induction therapy are shown in table 1. The total CR rate for the imatinib cohorts was significantly higher than for the pre-imatinib cohort (p=0.004). Table 1 Pre-Imatinib With Imatinib N=266 Total With Imatinib N=175 Part 1 Late Imatinib N=86 Part 2 Early Imatinib N=89 Died in induction<d56 5 5 3 7 Survived induction but never achieved remission 13 3 5 1 Total not achieving CR 18 8 8 8 CR on protocol induction 67 77 73 80 Total CR rate (includes those achieving remission later than post induction) 82 92 92 92 Pre- Imatinib, only 28% of patients went on to receive alloHSCT as per protocol. With any Imatinib, 44% of patients received alloHSCT as per protocol. Survival outcomes of patients in the 3 cohorts are shown in the table 2. Overall survival (OS), event free survival (EFS) and relapse free survival (RFS) are all at 3 years with 95% confidence intervals (CI) shown in brackets. The P values are for two comparisons - ** denotes the comparison between patients receiving any Imatinib and patients receiving none and ^ denotes the comparison between the Early and Late Imatinib cohorts. Table 2 Pre-Imatinib With Imatinib Total With Imatinib Part 1 Late Imatinib Part 2 Early Imatinib % OS (95% CI) (see also Figure 1) 25 (20–30) 42 (34–49) 34 (24–44) 48 (36–60) p=0.0001** p=0.05^ % EFS (95% CI) 19 (14–24) 36 (29–44) 29 (19–38) 45 (34–56) p=0.0001** p=0.04^ % RFS (95% CI) 36 (28–43) 54 (45–63) 45 (33–57) 62 (50–75) p=0.0001** p=0.02^ Figure 1 Three-year OS for patients who received per protocol alloHSCT was 59% vs. 28% (with no plateau on the curve) for those who did not receive alloHSCT as per protocol. By comparison, pre-imatinib, 5 year OS was 40% for transplanted- and 19% for non-transplanted patients. Hence, the extent to which Imatinib without subsequent alloHSCT can improve the outcome for adult Ph+ ALL is not yet clear. Figure 1. Three-year OS for patients who received per protocol alloHSCT was 59% vs. 28% (with no plateau on the curve) for those who did not receive alloHSCT as per protocol. By comparison, pre-imatinib, 5 year OS was 40% for transplanted- and 19% for non-transplanted patients. Hence, the extent to which Imatinib without subsequent alloHSCT can improve the outcome for adult Ph+ ALL is not yet clear. In conclusion, receiving any Imatinib during induction for Ph+ ALL significantly enhances CR rate and increase alloHSCT rate. This translates into a highly significant EFS, OS and RFS advantage to receiving Imatinib during therapy. An earlier start to Imatinib is significantly better than a later start. Though comparisons between study cohorts are not randomised, the large differences seen are unlikely to be explained by factors other than treatment. There can be no basis for omitting Imatinib from the initial therapy of adult patients with Ph+ ALL. However, our data show that the best outcome is seen when patients receive Imatinib followed by myeloablative alloHSCT, where nearly 60% of such patients survive 3 years from diagnosis. Disclosures: Goldstone: Roche: Honoraria, Speakers Bureau.

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Jennane, S., K. Doghmi, E. M. Mahtat, N. Messaoudi, B. Varet, and M. Mikdame. "Bing and Neel Syndrome." Case Reports in Hematology 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/845091.

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Introduction. We report the case of a Bing and Neel syndrome revealed by an isolated left ptosis.Case Report. a 57-year-old man was followed up since October 2003 for a typical Waldenström’s macroglobulinemia. A first complete remission was obtained with chlorambucil. In August 2004, he relapsed. A second complete remission was obtained with RFC chemotherapy regimen (rituximab, fludarabine, and cyclophosphamide). In October 2009, the patient presented with an isolated left ptosis revealing a Bing and Neel syndrome. The diagnosis was suspected on MRI and confirmed by the detection in the CSF of a monoclonal IgM similar to the one found in the plasma. A quite good partial remission has been obtained after one course of RDHAP (rituximab, dexamethasone, cytarabine, and cisplatin) and 3 courses of RDHOx (rituximab, dexamethasone, cytarabine, and oxaliplatin), in addition to ten intrahectal chemotherapy injections. The treatment was followed by intensification and autologous stem cell transplantation. At D58, the patient died due to a septic shock.Conclusion. BNS is a rare and potentially treatable complication of WM. It should be considered in patients with neurologic symptoms and a history of WM.

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Moraes, Claudia Letícia. "Mundo em desencanto em tempos de guerra civil." Revista de Ciências Sociais 52, no. 1 (January 31, 2021): 139–62. http://dx.doi.org/10.36517/10.36517/rcs.52.1.d06.

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A presente investigação visa empreender uma leitura do romance Antes de Nascer o Mundo (2009), do moçambicano Mia Couto, considerando alguns eixos norteadores das representações feitas pelo autor. Assim, por se tratar de uma narrativa que está centrada na vida de personagens que estão escondidos no interior da savana africana a fim de fugir das agruras da guerra, a análise que ora propomos pretende considerar de que maneira a narrativa intenta elaborar e superar determinados traumas causados pela guerra civil moçambicana do pós-independência. Para tanto, serão utilizados como escopo teórico autores como Nazir Can (2020), Elena Brugioni (2019, 2012) e Jane Tutikian (2006) para compreender os mecanismos utilizados pelo autor na intenção de retratar traumas de guerra, esfacelamentos familiares e a própria linguagem elaborada por Couto na representação de uma Moçambique tomada de assalto por conflitos internos.

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Caliendo, Lorenzo, Fernando Parro, and Aleh Tsyvinski. "Distortions and the Structure of the World Economy." American Economic Journal: Macroeconomics 14, no. 4 (October 1, 2022): 274–308. http://dx.doi.org/10.1257/mac.20190410.

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We model the world economy as one system of endogenous input-output relationships subject to frictions and study how the world’s input-output structure and world’s GDP change due to changes in frictions. We derive a sufficient statistic to identify frictions from the observed world input-output matrix, which we fully match for the year 2011. We show how changes in internal frictions impact the whole structure of the world’s economy and that they have a much larger effect on world’s GDP than external frictions. We also use our approach to study the role of internal frictions during the Great Recession of 2007–2009. (JEL D57, E16, E23, E32, F41, G01)

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Kuwata, M., Y. Kondo, Y. Miyazaki, Y. Komazaki, J. H. Kim, S. S. Yum, H. Tanimoto, and H. Matsueda. "Cloud condensation nuclei activity at Jeju Island, Korea in spring 2005." Atmospheric Chemistry and Physics Discussions 7, no. 6 (November 13, 2007): 15805–51. http://dx.doi.org/10.5194/acpd-7-15805-2007.

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Abstract. We measured the number concentrations of cloud condensation nuclei (CCN) and the size distributions of CCN/CN (CN: condensation nuclei) ratios at supersaturations (SSs) of 0.097, 0.27, 0.58, and 0.97% at Jeju-Island, Korea during March-April 2005. Measurements of aerosol inorganic ions, water-soluble organic carbon (WSOC), organic carbon (OC), and elemental carbon (EC) in PM2.5 were simultaneously made. The CCN/CN ratios increased with increasing particle diameter, and the diameter at CCN/CN=0.5 was defined as D50. D50 represents the activation dry diameter of atmospheric particles. The average D50 at SS=0.097% and 0.97% was 136 nm and 31 nm, respectively. The temporal variation of D50 at SS=0.097% was correlated with the mass fraction of water-soluble components (inorganic ions + WSOC), indicating that the temporal variation of CCN activity was mainly controlled by changes in the water-soluble components fraction. The critical dry diameter (Dcrit), which is the threshold dry diameter for CCN activation, was calculated from the observed aerosol chemical compositions by Köhler theory for comparison with D50. The D50 at SS=0.097% was correlated (r2=0.48) with calculated Dcrit, although Dcrit were larger than D50 by 20–29% on average. The systematic difference between D50 and Dcrit could be caused by the size dependence of the aerosol chemical compositions or surface tension lowering caused by the mixing of water-soluble organic compounds. This difference corresponds to a 27±14% uncertainty in the CCN number concentration estimated from the observed particle number size distribution.

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Kuwata, M., Y. Kondo, Y. Miyazaki, Y. Komazaki, J. H. Kim, S. S. Yum, H. Tanimoto, and H. Matsueda. "Cloud condensation nuclei activity at Jeju Island, Korea in spring 2005." Atmospheric Chemistry and Physics 8, no. 11 (June 11, 2008): 2933–48. http://dx.doi.org/10.5194/acp-8-2933-2008.

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Abstract. We measured the number concentrations of cloud condensation nuclei (CCN) and the size distributions of CCN/CN (CN: condensation nuclei) ratios at supersaturations (SSs) of 0.097, 0.27, 0.58, and 0.97% at Jeju Island, Korea during March-April 2005. We made simultaneous measurements of aerosol inorganic ions, water-soluble organic carbon (WSOC), organic carbon (OC), and elemental carbon (EC) in PM2.5. The CCN/CN ratios increased with increasing particle diameter, and the diameter at CCN/CN=0.5 was defined as D50. D50 represents the activation dry diameter of atmospheric particles. The average D50 at SS=0.097% and 0.97% was 136±17 nm and 31±3 nm, respectively. The temporal variation of D50 at SS=0.097% was correlated with the mass fraction of water-soluble components (inorganic ions + WSOC), indicating that the temporal variation of CCN activity was mainly controlled by changes in the water-soluble components fraction. The critical dry diameter (Dcrit), which is the threshold dry diameter for CCN activation, was calculated from the observed aerosol chemical compositions by Köhler theory for comparison with D50. The D50 at SS=0.097% was correlated (r2=0.48) with calculated Dcrit, although Dcrit was larger than D50 by 20–29% on average. The systematic difference between D50 and Dcrit could be caused by the size dependence of the aerosol chemical compositions or surface tension lowering caused by the mixing of water-soluble organic compounds. This difference corresponds to a 27±14% uncertainty in the CCN number concentration estimated from the observed particle number size distribution.

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Ozovehe, Abdulhamid A., Tasiu A. Sulaiman, Amana Ocholi, Jibrin M. Kaura, and Ashiru Mohammed. "Effects of Load Ratio Variation on the Safety of Timber Concrete Composite Floor." FUOYE Journal of Engineering and Technology 7, no. 2 (June 8, 2022): 269–74. http://dx.doi.org/10.46792/fuoyejet.v7i2.779.

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This paper presents the structural reliability appraisal of timber concrete composite floor designed in line with Eurocode 5 (2004) and Eurocode 2, (2004). Limit state expressions for timber concrete composite floor subdued to tension, bending, tension and bending, shear and compression were generated and their entailed reliability degrees were assessed. The basic variables associated with the design are considered to be random variables with their properties espoused from the previous studies. Reliability analysis was performed using reliability mothed i.e. first order reliability method (FORM) owing to assess the safety levels of the composite floor structural elements by considering six different modes of failure. The analysis comprised of different selected species of softwood, hard wood and glue laminated timber whose strength class were obtained from BS EN 338, 2008 and concrete of strength class C30 from Eurocode 2. The results obtained disclosed that safety indices decrease as the load ratio steps up that led to cut down of the strength. It was detected that timber with strength classes D70, D50 and C50 are safe against all different failure modes looked at except C50 and D50 against shear failure at load ratio of 1, 1.5 and 2. It was conclude timber of strength classes D70, D50 and C50 would reliable for the construction of composite floor i.e. timber-concrete floor.

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Alamsyah, Alamsyah. "PERANCANGAN STRUKTUR ATAS JEMBATAN SEI. LUKUT DENGAN STRUKTUR KOMPOSIT (PEMBEBANAN BERDASARKAN SNI 1725:2016)." Jurnal TeKLA 4, no. 1 (August 23, 2022): 26. http://dx.doi.org/10.35314/tekla.v4i1.2638.

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Jembatan lukut terletak di Jalan Simpang Pramuka di Kecamatan Rumbai, Kota Pekanbaru. Jembatan ini penghubung jalan Simpang Pramuka Menuju ke Kota Perawang, Kecamatan Tualang, Kabupaten Siak. Jembatan Sungai Lukut ini memiliki bentang panjang 20 m dengan lebar 11 m dan terbuat dari beton bertulang, kondisi jembatan ini masih baik dengan kokoh dikarenakan masih baru dibangun. Perubahan standar pembebanan dan belum ada data atau informasi yang jelas tentang desain jembatan tersebut, maka dilakukan rencana ulang yang menggunakan beban SNI 1725:2016 dan diterapkan pada jembatan komposit. Pada perencanaan ini dilakukan pembebanan analisa terbaru yakni menggunakan pembebanan jembatan SNI 1725:2016, slab beton mengacu SNI T-12-2004 dan girder baja mengacu pada RSNI T-03-2005. Hasil yang diperoleh adalah berupa tulangan utama negatif dan positif slab D16-250 mm dan tulangan bagi D13-300 mm. Trotoar diperoleh tulangan utama D16-200 mm dan tulangan bagi Ø10-250 mm. Untuk tiang Railing mendapatkan tulangan lentur 4Ø10 dan tulangan geser Ø6-150 mm. Plat injak diperoleh tulangan arah memanjang dan melintang D16-250 mm. Ukuran girder yang digunakan ukuran profil WF 800x 300x14x26 mm dan dimensi diafragma yang digunakan ukuran profil WF 450x200x9x14 mm dengan sambungan type Extended End-Plate.

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Cozzi, F., W. H. Powell, and C. Thilgen. "Numbering of Fullerenes (IUPAC Recommendations 2004)." Pure and Applied Chemistry 77, no. 5 (January 1, 2005): 843–923. http://dx.doi.org/10.1351/pac200577050843.

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Rules for numbering (C60-Ih)[5,6]fullerene and (C70-D5h(6))[5,6]fullerene were codified in a publication “Nomenclature for the (C60-Ih)[5,6] and (C70-D5h(6))[5,6]fullerenes” published in Pure Appl. Chem.74 (4), 629–695 (2002). The current publication contains recommendations for numbering a wide variety of fullerenes of different sizes, with rings of different sizes, from C20 to C120, and of various point group symmetries, including low symmetries such as Cs, Ci, and C1, as well as many fullerenes that have been isolated and well characterized as pristine carbon allotropes or as derivatives. These recommendations are based on the principles established in the earlier publication and aim at the identification of a well-defined and preferably contiguous helical pathway for numbering. Rules for systematically completing the numbering of fullerene structures for which a contiguous numbering pathway becomes discontiguous are presented.

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NAKANISHI, Tatsuya, Kenji TERABAYASHI, Yuki HASHIMOTO, Yuma HOSHIKAWA, and Kazunori UMEDA. "1A1-D16 Measurement of Multiple Persons Using a Subtraction Stereo." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _1A1—D16_1—_1A1—D16_4. http://dx.doi.org/10.1299/jsmermd.2009._1a1-d16_1.

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ISHIKAWA, Tatsuya, and Shoichi HASEGAWA. "2A1-D16 Proposal of Motion Design Tool for Real Robots." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _2A1—D16_1—_2A1—D16_2. http://dx.doi.org/10.1299/jsmermd.2009._2a1-d16_1.

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Kjellander, Christian, Emma Hernlund, Moa Ivergård, Axel Svedbom, Therese Dibbern, Anna Stenling, Fredrik Sjöö, Simona Vertuani, Andreas Glenthøj, and Honar Cherif. "Sickle Cell Disease in Sweden - Prevalence and Resource Use Estimated through Population-Based National Registers." Blood 138, Supplement 1 (November 5, 2021): 2040. http://dx.doi.org/10.1182/blood-2021-147336.

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Abstract BACKGROUND Sickle cell disease (SCD) is an autosomal recessive disorder characterized by abnormal hemoglobin. SCD causes hemolytic anemia, vaso-occlusion leading to vaso-occlusive crises (VOC) and contributing to organ damage and early death. SCD is most prevalent in sub-Saharan Africa and the Middle East, but also countries such as Brazil, India and US, have comparatively high frequencies of SCD. Global migration has contributed to a greater geographical spread. The prevalence of SCD in Sweden is unknown. OBJECTIVE The primary objectives of this study were to estimate the 1-year prevalence of SCD and SCD-associated resource use in Sweden. Secondary objectives were to estimate birth incidence, treatment patterns and survival. PATIENTS Patients with an ICD-10 diagnosis code for SCD (any D57 [excluding D57.3, sickle cell trait]) were identified from the Swedish Patient Registry (between January 1 st 2001 and June 30 th 2018). Patients were assessed for 1-year prevalence and resource use per calendar year for a follow-up period of 13 years (2006-2018). METHODS Patients were considered prevalent from birth or immigration to death or emigration. Resource use from specialized care, including all events recorded in the registry with any D57 as the main diagnosis was assessed in the follow up period 2006-2018 as number of outpatient visits and inpatient stays. Costs for this hospital resource use were estimated through remuneration amounts based on diagnosis related groups. Data on sick leave days and days with disability pension due to SCD in patients in working age (18-65 years) were retrieved from the Swedish Social Security Agency and costed with the mean salary in Sweden, plus social security contributions. Costs are reported in 2019 Swedish Krona (SEK, ≈$ 0.1). RESULTS One-year prevalence of all SCD diagnosis increased from 504 patients (5.53 per 100,000 population) in 2006 to 670 patients (6.55 per 100,000 population) in 2018. The 1-year prevalence of SCD patients ever recorded with an ICD-10 code for SCD with VOC (D57.0) increased from 139 patients (1.53 per 100,000 population) in 2006 to 260 patients (2.54 per 100,000 population) in 2018. The proportion of prevalent patients that were born in Sweden decreased over the years, from approximately 55% in the beginning of the study period to 45% in the end of the study period. The mean and median age of the SCD population decreased over the study period. Individuals with SCD and VOC were, on average younger than the other SCD (D57) subgroups. Birth incidence was captured by calendar year 2006-2018 and was highest in 2007 with 15 children born with SCD. For Swedish-born children with SCD during the patient identification time (n=123), the mean time to identification in the registers was 2.6 years (SD 2.7, range 0-16 years). Hospital outpatient visits and inpatient stays with SCD (all events with D57 recorded) as main diagnosis increased from 57 to 189, and 250 to 1,003, respectively, over the years 2006-2018. This corresponded to costs of inpatient care increasing from 1.4 million (M) SEK in 2006 to 7.3 M SEK in 2018 and costs of outpatient visits increasing from 0.9 M SEK in 2006 to 4.6 M SEK in 2018. The vast majority of costs were incurred in individuals ever recorded with a SCD with VOC diagnosis (D57.0). The most frequent hospital treatment was blood transfusion, with 8-11% of patients receiving transfusion in each year studied, especially common in SCD and VOC diagnosis. The prescribed treatment with the highest increase of uptake over the study period were hydroxyurea, vitamins and paracetamol in all SCD. Individuals in working age had on average 2.3 days of sick leave per patient-year due to SCD (D57), and approximately 4% of these patients received disability benefits because of their SCD. During the follow-up period, the median age at death was 74 years for all SCD and 69 years for SCD with crisis, this is 7-10 years and 12-15 years less compared to the Swedish general population respectively. CONCLUSION This study demonstrates that the prevalence, hospital resource use and associated costs have increased substantially in Sweden. In an era of emerging treatments for SCD we have for the first time comprehensively described epidemiological-, disease-related and economical aspects of SCD in Sweden. Disclosures Hernlund: ICON: Current Employment. Ivergård: ICON: Current Employment. Svedbom: ICON: Current Employment. Dibbern: Novartis: Current Employment. Stenling: Novartis: Current Employment. Sjöö: Novartis: Ended employment in the past 24 months. Vertuani: Novartis: Current Employment. Glenthøj: Saniona: Research Funding; Bristol Myers Squibb: Consultancy; Agios: Consultancy; Novo Nordisk: Honoraria; Novartis: Consultancy; Alexion: Research Funding; Sanofi: Research Funding; Bluebird Bio: Consultancy.

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KUMAGAI, Hikaru, Soichiro MORISHITA, Kuniaki KAWABATA, Hajime ASAMA, and Taketoshi MISHIMA. "1A1-D06 Asbestos Detection Method with Frequency Analysis for Microscope Images." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _1A1—D06_1—_1A1—D06_4. http://dx.doi.org/10.1299/jsmermd.2009._1a1-d06_1.

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Togasaki, Mitsutoshi, and Hiroshi IGARASHI. "1A2-D06 Manipulator Control with Flexible Objects Model by Neural Network." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _1A2—D06_1—_1A2—D06_2. http://dx.doi.org/10.1299/jsmermd.2009._1a2-d06_1.

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MATSUDA, Takuya, Masahito IKEDA, Takahiro ASO, Yusuke OKUDAIRA, and Yoshihiro KAI. "1P1-D16 Development of a Robot Manipulator Equipped with Mechanical Safety Devices." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _1P1—D16_1—_1P1—D16_3. http://dx.doi.org/10.1299/jsmermd.2009._1p1-d16_1.

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Pattloch, Dagmar. "Sichelzellkrankheit unter Neugeborenen in Deutschland: Eine Studie an Routinedaten der AOK." Das Gesundheitswesen 81, no. 12 (October 17, 2018): 986–92. http://dx.doi.org/10.1055/a-0719-5165.

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Zusammenfassung Hintergrund Die Sichelzellkrankheit (SCD, ICD-10:D57) ist eine autosomal rezessiv vererbte Hämoglobinkrankheit mit globaler Public-Health-Relevanz. In Deutschland kommen pro Jahr 70–150 Kinder mit SCD zur Welt (1–2 je 10 000 Neugeborene). Die Früherkennung im asymptomatischen ersten Vierteljahr wäre leitliniengerecht und sekundärpräventiv bedeutsam. Ziel der Studie Das Ziel dieser Arbeit ist 1) die Ermittlung der Prävalenz von SCD in Routinedaten von AOK-versicherten Neugeborenen, 2) die Messung des Alters bei der Erstdiagnose D57, 3) die Zählung charakteristischer Krankenhausdiagnosen. Methode Analysiert wurden ambulante und stationäre Routinedaten von 204 AOK-versicherten Kindern. Dies sind alle, die 2009–2010 geboren sind, mindestens einen Tag im Geburtsjahr AOK-versichert waren und innerhalb von 6 Kalenderjahren jemals einen Code D57 erhielten. Die Anzahl Neugeborener in der AOK 2009–2010 (Nennerpopulation) ist bekannt. SCD-Fälle (Zähler) gelten als validiert, wenn D57 (außer D57.3) in mindestens 2 Quartalen (Q) codiert wurde. Es wird die Prävalenzproportion mit Bootstrap-Konfidenzintervall (CI) berechnet. Pro Fall wird quartalsgenau ausgelesen, wann D57 erstmals auftaucht. Der Standardized Incidence Ratio (SIR) wird berechnet für Krankenhausfälle vom Monat 13 bis Monat 61 im Vergleich zur Bevölkerung gleichen Geschlechts und Alters (1 bis unter 5 Jahre). Die Auswertung erfolgt mit SPSS 22 und Excel. Ergebnis Nach interner Validierung resultierten 78 Fälle von SCD. Die Prävalenz beträgt 1,96 (95% CI 1,53–2,41) pro 10 000 Neugeborene. Regionale Schwerpunkte zeigten sich in Berlin, Bremen, Hamburg (zusammengefasst) sowie in Nordrhein-Westfalen. Die Erstnennung von D57 erfolgte nur bei 15,4% der Fälle früh, d. h. in Q1–2. Der Median liegt in Q7. In 78 Fällen ereigneten sich 266 Krankenhausfälle mit einem SIR=6,8, d. h. die Hospitalisierungsrate ist 6,8fach höher als die der Bevölkerung. Unter den Entlassungsdiagnosen fanden sich gefürchtete Outcomes wie Pneumonie, Sepsis und Milzerkrankungen. Schlussfolgerung SCD in Deutschland lässt sich mit Routinedaten der größten gesetzlichen Krankenkasse plausibel darstellen. Derzeit wird die Krankheit zu selten frühzeitig erkannt. Die Zeit bis zur Erkennung ließe sich entscheidend verkürzen durch Aufnahme von SCD in das Neugeborenenscreening. Bis eine solche Lösung erreicht ist, sollten Eltern mit Migrationshintergrund und Fachleute ihre Aufmerksamkeit für SCD erhöhen.

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XU, CHUN-JIE, YI-MIN LIU, XIAO-FENG YIN, and ZHAN-JUN ZHANG. "A NOTE ON "CHAIN TELEPORTATION WITH PARTIALLY ENTANGLED STATES"." International Journal of Quantum Information 08, no. 08 (December 2010): 1421–26. http://dx.doi.org/10.1142/s0219749910006393.

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The global chain teleportation protocol (GCTP) [Eur. Phys. J. D54 (2009) 111] is revisited via a three-node instantiation. The required operation ability and manipulation orderings of the three participants are sightly changed so that in the improved version, three additional important merits are resultant with consuming only an additional one-classical-bit message.

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Yoshida, Tatsuro, Jaesung Imu, Yasushi Nakada, Hiroshi Okajima, Nobutomo Matsunaga, and Shigeyasu Kawaji. "1P1-D06 Evolution of Steer-by-Wire control system with nonlinear scaling gain." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _1P1—D06_1—_1P1—D06_2. http://dx.doi.org/10.1299/jsmermd.2009._1p1-d06_1.

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Suga, Yuki, Wei Wang, and Shigeki Sugano. "2A1-D06 Development of Wheel Chair Mounted Robot Arm System using RT-Middleware." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _2A1—D06_1—_2A1—D06_4. http://dx.doi.org/10.1299/jsmermd.2009._2a1-d06_1.

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HOSHI, Katsuyuki, and Yasuhiro FUKUOKA. "2P1-D16 Remote Control of a Crawling Robot Running Swiftly on Irregular Terrains." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _2P1—D16_1—_2P1—D16_4. http://dx.doi.org/10.1299/jsmermd.2009._2p1-d16_1.

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Giynasiar Fatah, Akbar, Ahmad Ridwan, and Sigit Winarto. "Studi Perencanaan Bangunan Atas Gedung Permata Indah di Desa Kedung Dowo Kabupaten Nganjuk." Jurnal Manajemen Teknologi & Teknik Sipil 3, no. 2 (October 30, 2020): 289. http://dx.doi.org/10.30737/jurmateks.v3i2.1139.

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Building construction is an object of a certain part of a building. Planning an earthquake-resistant building structure, one of the methods used is the Intermediate Moment Bearer Frame System (SRPMM). Based on SNI 03-1726-2012, SNI 03- 2847-2013, and SNI 1727-2013. In modeling made using SAP 2000 V20. The planning of the Permata Indah building, which is in Nganjuk Regency, is reviewed using static equivalent and response spectrum. The moment-bearing frame system is when the components and joints resist bending, shear, and axial forces. In this case, the moment-bearing frame system has a concept on the ductile portal structure system for joints or joints between columns and plastic beams. The calculated structural part is a floor plate that uses evenly distributed loads in trapezoidal loads and triangular loads; beam and column systems use concrete with analysis and calculation using the SAP 2000 V20 program. 9-D16 stirrup reinforcement Ø10-80, beam size 20cm x 25cm with main reinforcement 6-D16 stirrup Ø10-90, column size 30 cmx55 cm with main reinforcement 10- D16 stirrup 3 Ø10-110, practical column 15cm x 15cm 10 -D19 stirrup 3 Ø10-110, x and y-direction plate size Ø10-150 and Ø10-150. Konstruksi bangunan merupakan suatu obyek dari bagian tertentu dari suatu bangunan. Perencanaan struktur bangunan tahan gempa, salah satu metode yang digunakan adalah Sistem Rangka Pemikul Momen Menengah (SRPMM). Berdasarkan SNI 03-1726-2012, SNI 03-2847-2013, dan SNI 1727-2013. Dalam pemodelan dibuat dengan menggunakan SAP 2000 V20. Perencanaan gedung Permata Indah yang berada di Kabupaten Nganjuk ditinjau dengan menggunakan statik ekuivalen dan spektrum respon. Sistem rangka bantalan momen adalah ketika komponen dan sambungan menahan gaya lentur, geser, dan aksial. Dalam hal ini sistem rangka bantalan momen mempunyai konsep pada sistem struktur portal daktail untuk sambungan atau sambungan antar kolom dan balok plastik. Bagian struktural yang dihitung adalah pelat lantai yang menggunakan beban merata pada beban trapesium dan beban segitiga; Sistem balok dan kolom menggunakan beton dengan analisa dan perhitungan menggunakan program SAP 2000 V20. Tulangan sanggurdi 9-D16 Ø10-80, ukuran balok 20cm x 25cm dengan tulangan utama sanggurdi 6-D16 Ø10-90, ukuran kolom 30 cmx55 cm dengan tulangan utama sanggurdi 10-D16 3 Ø10- 110, kolom praktis 15cm x 15cm 10 -D19 sanggurdi 3 Ø10-110, pelat searah x dan y ukuran Ø10-150 dan Ø10-150.

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Silva, Maurício. "O Nascimento da Gramática. Uso & Norma." Domínios de Lingu@gem 3, no. 2 (February 2, 2011): 243–45. http://dx.doi.org/10.14393/dl6-v3n2a2009-15.

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YAMAKOSHI, Masashi, Takefumi IIZAKA, Yoshitaka YOKOO, Ichiro KAWABUCHI, and Kiyoshi HOSHINO. "1A1-D06 Compact humanoid robot hand generating dexterous motions." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2006 (2006): _1A1—D06_1—_1A1—D06_2. http://dx.doi.org/10.1299/jsmermd.2006._1a1-d06_1.

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ITO, Tomotaka, Hiroyuki UESAKA, Yoshiharu SUZUKI, and Daiki KABURAGI. "1P1-D16 Realistic Information Monitoring Using 3D-stereo Display." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2006 (2006): _1P1—D16_1—_1P1—D16_3. http://dx.doi.org/10.1299/jsmermd.2006._1p1-d16_1.

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IGARASHI, Hiroshi, Akira TAKEYA, and Masayoshi KAKIKURA. "2P1-D06 Human Adaptive Assist Planning for Teleoperation System." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2006 (2006): _2P1—D06_1—_2P1—D06_4. http://dx.doi.org/10.1299/jsmermd.2006._2p1-d06_1.

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TAMURA, Yusuke, and Hajime ASAMA. "1A2-D16 Estimation of Pedestrian Intention by a Robot in Human-Robot Coexisting Environment." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _1A2—D16_1—_1A2—D16_2. http://dx.doi.org/10.1299/jsmermd.2009._1a2-d16_1.

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MARUYAMA, Hisataka, Fumihitro ARAI, Masaki ITO, Masahiro NAKAJIMA, and Toshio FUKUDA. "2P1-D16 On-Chip Cell Measurement System Using Functional Microtool." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2008 (2008): _2P1—D16_1—_2P1—D16_4. http://dx.doi.org/10.1299/jsmermd.2008._2p1-d16_1.

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KUSUMOTO, Takuya, Tatsuya SHIRAI, and Takumi TOMIOKA. "1A1-D26 Development of Hemisphere-shaped Mobile Robot Giga-Bowl." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2006 (2006): _1A1—D26_1—_1A1—D26_2. http://dx.doi.org/10.1299/jsmermd.2006._1a1-d26_1.

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TSUJIUCHI, Nobutaka, Takayuki KOIZUMI, Masashi HASHIMOTO, and Yuka ISOME. "2P1-D06 Angle Detection of Inclined Plane using Visual Information." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2007 (2007): _2P1—D06_1—_2P1—D06_4. http://dx.doi.org/10.1299/jsmermd.2007._2p1-d06_1.

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Powell, W. H., F. Cozzi, G. P. Moss, C. Thilgen, R. J. R. Hwu, and A. Yerin. "Nomenclature for the C60-Ih and C70-D5h(6) fullerenes (IUPAC Recommendations 2002)." Pure and Applied Chemistry 74, no. 4 (January 1, 2002): 629–95. http://dx.doi.org/10.1351/pac200274040629.

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Fullerenes are a new allotrope of carbon characterized by a closed-cage structure consisting of an even number of three-coordinate carbon atoms devoid of hydrogen atoms. This class was originally limited to closed-cage structures with 12 isolated five-membered rings, the rest being six-membered rings. Although it was recognized that existing organic ring nomenclature could be used for these structures, the resulting names would be extremely unwieldy and inconvenient for use. At the same time it was also recognized that established organic nomenclature principles could be used, or adapted, to provide a consistent nomenclature for this unique class of compounds based on the class name fullerene. However, it was necessary to develop an entirely new method for uniquely numbering closed-cage systems. This paper describes IUPAC recommendations for naming and uniquely numbering the two most common fullerenes with isolated pentagons, the icosahedral C60 fullerene and a D5h-C70 fullerene. It also describes recommendations for adapting organic nomenclature principles for naming fullerenes with nonclosed-cage structures, heterofullerenes, derivatives formed by substitution of hydrofullerenes, and the fusion of organic rings or ring systems to the fullerene cage. Finally, this paper suggests methods for describing structures consisting of two or more fullerene units and for denoting configurations of chiral fullerenes and their derivatives.

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Zábori, J., N. Rastak, Y. J. Yoon, I. Riipinen, and J. Ström. "Size-resolved cloud condensation nuclei concentration measurements in the Arctic: two case studies from the summer of 2008." Atmospheric Chemistry and Physics Discussions 15, no. 4 (February 23, 2015): 5079–128. http://dx.doi.org/10.5194/acpd-15-5079-2015.

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Abstract. The Arctic is one of the most vulnerable regions affected by climate change. Extensive measurement data are needed to understand the atmospheric processes governing this vulnerability. Among these, data describing cloud formation potential are of particular interest, since the indirect effect of aerosols on the climate system is still poorly understood. In this paper we present, for the first time, size-resolved cloud condensation nuclei (CCN) data obtained in the Arctic. The measurements were conducted during two periods in the summer of 2008: one in June, and one in August, at the Zeppelin research station (78°54' N, 11°53' E) in Svalbard. Trajectory analysis indicates that during the measurement period in June 2008, air masses predominantly originated from the Arctic, whereas the measurements from August 2008 were characteristic of mid-latitude air masses. CCN supersaturation (SS) spectra obtained on the 27 June, before size-resolved measurements were begun, and spectra from the 21 and 24 August, conducted before and after the measurement period, revealed similarities between the two months. From the ratio between CCN concentration and the total particle number concentration (CN) as a function of dry particle diameter (Dp) at a SS of 0.4%, the activation diameter (D50), corresponding to CCN / CN = 0.50, was estimated. D50 was found to be 60 and 67 nm for the examined periods in June and August 2008, respectively. Corresponding D50 hygroscopicity parameter (κ) values were estimated to be 0.4 and 0.3 for June and August 2008, respectively. These values can be compared to hygroscopicity values estimated from bulk chemical composition, where κ was calculated to be 0.5 for both June and August 2008. While the agreement between the two months is reasonable, the difference in κ between the different methods indicates a size-dependence in the particle composition, which is likely explained by a higher fraction of sea salt in the bulk aerosol samples.

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Zábori, J., N. Rastak, Y. J. Yoon, I. Riipinen, and J. Ström. "Size-resolved cloud condensation nuclei concentration measurements in the Arctic: two case studies from the summer of 2008." Atmospheric Chemistry and Physics 15, no. 23 (December 15, 2015): 13803–17. http://dx.doi.org/10.5194/acp-15-13803-2015.

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Abstract. The Arctic is one of the most vulnerable regions affected by climate change. Extensive measurement data are needed to understand the atmospheric processes governing this vulnerability. Among these, data describing cloud formation potential are of particular interest, since the indirect effect of aerosols on the climate system is still poorly understood. In this paper we present, for the first time, size-resolved cloud condensation nuclei (CCN) data obtained in the Arctic. The measurements were conducted during two periods in the summer of 2008: one in June and one in August, at the Zeppelin research station (78°54´ N, 11°53´ E) in Svalbard. Trajectory analysis indicates that during the measurement period in June 2008, air masses predominantly originated from the Arctic, whereas the measurements from August 2008 were influenced by mid-latitude air masses. CCN supersaturation (SS) spectra obtained on the 27 June, before size-resolved measurements were begun, and spectra from the 21 and 24 August, conducted before and after the measurement period, revealed similarities between the 2 months. From the ratio between CCN concentration and the total particle number concentration (CN) as a function of dry particle diameter (Dp) at a SS of 0.4 %, the activation diameter (D50), corresponding to CCN / CN = 0.50, was estimated. D50 was found to be 60 and 67 nm for the examined periods in June and August 2008, respectively. Corresponding D50 hygroscopicity parameter (κ) values were estimated to be 0.4 and 0.3 for June and August 2008, respectively. These values can be compared to hygroscopicity values estimated from bulk chemical composition, where κ was calculated to be 0.5 for both June and August 2008. While the agreement between the 2 months is reasonable, the difference in κ between the different methods indicates a size dependence in the particle composition, which is likely explained by a higher fraction of inorganics in the bulk aerosol samples.

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ENDO, Yasuhiro, Kazumi OIKAWA, and Shigenori OHKUBO. "2P2-D06 Navigation for Autonomous Mobile Robot Using Potential Function Method." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2008 (2008): _2P2—D06_1—_2P2—D06_4. http://dx.doi.org/10.1299/jsmermd.2008._2p2-d06_1.

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Byrne, Jennifer A., Sarah Frost, Yuyan Chen, and Robert K. Bright. "Tumor protein D52 (TPD52) and cancer—oncogene understudy or understudied oncogene?" Tumor Biology 35, no. 8 (May 6, 2014): 7369–82. http://dx.doi.org/10.1007/s13277-014-2006-x.

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41

NISHINO, Tamaki, Yoshinao SODEYAMA, Tomoaki YOSHIKAI, Ikuo MIZUUCHI, Tetsunari INAMURA, and Masayuki INABA. "2A1-D36 A Visually Guided Reaching Behavior by a Musculoskeletal Humanoid." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2006 (2006): _2A1—D36_1—_2A1—D36_2. http://dx.doi.org/10.1299/jsmermd.2006._2a1-d36_1.

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42

TSUTSUMI, Kazuyoshi. "1A1-D16 A Consideration on Mechanical Communication between Humans by Machines." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2008 (2008): _1A1—D16_1—_1A1—D16_2. http://dx.doi.org/10.1299/jsmermd.2008._1a1-d16_1.

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43

YANO, Sho, and Kenji SUZUKI. "1P1-D06 Design of Robotic Skin to Assist Cognitive-Motor Function." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2008 (2008): _1P1—D06_1—_1P1—D06_2. http://dx.doi.org/10.1299/jsmermd.2008._1p1-d06_1.

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44

Nascimento, Maria Isabel do, Felipe Correa Massahud, Cassio Destefani Lopes, Nathalia Giacomo Barbosa, Vanessa da Costa Rodrigues, and Alfredo de Almeida Cunha. "Mortalidade prematura por câncer do colo do útero em Niterói e São Gonçalo, de 2000 a 2015." Jornal Brasileiro de Ginecologia 129, no. 2 (2019): 28. http://dx.doi.org/10.5327/jbg-0368-1416-2019129224.

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Introdução: Mortalidade prematura corresponde a óbitos de pessoas na faixa de 30 a 69 anos. Embora o rastreamento do câncer do colo do útero (CCU) seja dirigido prioritariamente a mulheres de 25 a 64 anos, os óbitos acontecem mais frequentemente nessa mesma faixa etária. Objetivo: Estimar as taxas de mortalidade por CCU em Niterói e São Gonçalo, de 2000 a 2015, entre mulheres residentes na faixa de idade de 30 a 69 anos e analisar o efeito da adesão ao Pacto Pela Saúde na mortalidade por esse tipo de câncer. Métodos: Estudo descritivo de séries temporais conduzido com dados de óbitos obtidos no Departamento de Informática do Sistema Único de Saúde DATASUS, consultando o Sistema de Informações sobre Mortalidade. Calcularam-se taxas específicas de mortalidade por CCU, por faixa etária (3039; 40‒49, 50‒59, 60‒69), dos municípios de São Gonçalo e Niterói, de 2000 a 2015. Para o cálculo das taxas específicas, consideraram-se no numerador os óbitos corrigidos (etapas de correção de óbitos: (i) redistribuição dos óbitos por câncer do útero, porção não especificada (C55); (ii) inclusão dos casos de óbito por CID D06 (carcinoma in situ do colo do útero) e N87 (displasia acentuada do colo do útero); (iii) redistribuição dos óbitos com causa básica mal definida (CID R00-R99)) e, no denominador, considerou-se a população residente na mesma faixa etária e localidade. Fez-se a padronização das taxas segundo a população mundial de 1960, e apresentaram-se os coeficientes por 100 mil mulheres. Realizaram-se as análises de tendência pela inspeção visual de gráficos e pela regressão de Prais-Winsten, para o período todo (2000‒2015), para o período antes do Pacto pela Saúde (2000‒2006) e para o período depois da sua implantação (2009‒2015). Resultados: As taxas de São Gonçalo foram sistematicamente mais elevadas que as de Niterói. As faixas de idade mais altas tiveram também as maiores taxas em ambos os municípios. No início do período de análise (ano 2000), as taxas foram de 12,48 por 100 mil mulheres e de 20,64 por 100 mil mulheres para Niterói e São Gonçalo, respectivamente. No encerramento do período (2015), São Gonçalo apresentou taxas mais elevadas (28,53 por 100 mil mulheres) que no início do período, enquanto Niterói apresentou importante redução (3,86 por 100 mil). A regressão de Prais-Winsten mostrou tendência estacionária em ambos os municípios e não evidenciou efeito da adesão ao Pacto pela Saúde nesse indicador de mortalidade. Conclusão: A análise de situação de saúde ao longo dos anos de 2000 a 2015 indica que a mortalidade prematura por CCU é alta em Niterói e em São Gonçalo, mas é mais grave neste último município. A implantação do Pacto pela Saúde e as políticas dele derivadas não impactaram esse importante indicador de saúde, embora os dois municípios tenham aderido precocemente às determinações de gestão e político-administrativas nele contidas.

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SUZUMORI, Koichi, and Fumitaka SAITO. "2P1-D06 Micro Rubber Structures for Passive Walking : 2nd report; Integration and Miniaturization by Stereo Lithography Mold." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2009 (2009): _2P1—D06_1—_2P1—D06_4. http://dx.doi.org/10.1299/jsmermd.2009._2p1-d06_1.

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46

Sousaraei, Naeimeh, Benjamin Torabi, Elias Soltani, Kambiz Mashayekhi, and Joaquín Medina. "Differential Seed Germination Responses of Tomato Landraces to Temperature under Climate Change Scenarios." Seeds 1, no. 1 (March 7, 2022): 36–48. http://dx.doi.org/10.3390/seeds1010005.

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This study aims to quantify the seed germination response of six tomato landraces to temperature; predict future climate changes relative to the baseline period (1980–2009) for studied locations in the courses of near-term (2010–2039) and mid-term (2040–2069) under two representative concentration pathways (RCP 4.5 and 8.5); assess the impact of future climate change on the final germination percentage (FGP) and time to reach 50% germination (D50) in the studied landraces. The results show that FGP is zero at 10 °C, reaches the highest value at 15–35 °C, and ceases at 36–40 °C for all landraces. The results also demonstrate that the temperature increment is 0.8–1.3 °C and 1.5–2.7 °C in the near- and mid-term, respectively, under RCP 4.5; further, this increment is 0.9–1.9 °C for the near-term and 2.3–3.4 °C for the mid-term under RCP 8.5. It estimates that the D50 takes 2.5 to 3.8 days among the locations in the baseline course. In the near term, the D50 would be 2.2 to 3.4 days under RCP 4.5 and 2.1 to 3.3 days under RCP 8.5. For the mid-term, the D50 would be projected between 1.9 and 2.9 days under RCP 4.5 and 1.8 to 2.7 days under RCP 8.5. The FGP increases up to 19.5% for Gorgan and 21.3% for Varamin under climatic scenarios relative to baseline, and it will not change in the future climate for other landraces. In conclusion, global warming can result in rapid, uniform, and complete germination in different tomato landraces.

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Lucardie, A. P. M. "M.S. van der Land, Tussen ideaal en illusie. De geschiedenis van D66, 1966-2003." BMGN - Low Countries Historical Review 119, no. 2 (January 1, 2004): 299. http://dx.doi.org/10.18352/bmgn-lchr.6080.

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SAITO, Jun, Masayoshi KAMIJO, Tsugutake SADOYAMA, and Yoshio SHIMIZU. "1P1-D26 Fundamental study on touch measurement system to evaluate fabric hand." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2006 (2006): _1P1—D26_1—_1P1—D26_2. http://dx.doi.org/10.1299/jsmermd.2006._1p1-d26_1.

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KOBAYASHI, Seiya, and Keiji SUZUKI. "2A1-D16 The mounting of humanoid robot for an action in underwater." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2006 (2006): _2A1—D16_1—_2A1—D16_2. http://dx.doi.org/10.1299/jsmermd.2006._2a1-d16_1.

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NISHIMURA, Soh, Hiroshi TAKEMURA, and Hiroshi MIZOGUCHI. "2P1-D16 A Study on Robotizing Daily Items : Robotizing the Shopping Cart." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2006 (2006): _2P1—D16_1—_2P1—D16_2. http://dx.doi.org/10.1299/jsmermd.2006._2p1-d16_1.

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