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1

Can, Elif [Verfasser]. "Supervisors’ perspective on medical thesis projects and dropout rates : survey among thesis supervisors at a large German university hospital / Elif Can." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2017. http://d-nb.info/1133493017/34.

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Merriman, Colin Clarke. "Orientation dependence of dislocation structure evolution of aluminum alloys in 2-D and 3-D." Online access for everyone, 2007. http://www.dissertations.wsu.edu/Thesis/Summer2007/C_Merriman_072507.pdf.

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Ansari, Akbar. "Evaluatin Strategy for Candidates drug and implementation to product D : MBA-thesis in marketing." Thesis, University of Gävle, Department of Business Administration and Economics, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-694.

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Biovitrumis is one of the larger biopharma companies in Euprope and conducts research in different niche areas. One of the interested areas for Biovitrum is Exocrine Pancreatic insufficiency. Biovitrum has a candidate drug (product D) in early development process for treatment of. Exocrine Pancreatic Insufficiency.

The Drug development is a long, complicated and costly process. Therefore, it is very important for managers to know the commercial value of a future drug. The purpose of this report is to develop a model for evaluation of candidate drug in early development phase and analysis of market potential for product D for treatment of Chronic pancreatitis. Chronic pancreatitis is disease within sub group of Exocrine Pancreatic Insufficiency.

The deductive reasoning approach and quantitative data is used in this report. Only secondary data is collected for this study. The sources of secondary data are research papers, Google Pub-Med database and consultant companies.

A new model is developed for evaluation of candidate drug .This model can analyse the market potential, unmet medical need, and calculate net present values. This study shows that there is unmet medical need in chronic pancreatitis. The result also shows that product D has comparative advantages over present products in the market and future competitors. The product D can full fill the unmet medical need for treatment of Chronic pancreatitis

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Sengupta, Shantashree [Verfasser]. "E-thesis repositories in the world : A critical analysis / Shantashree Sengupta." München : GRIN Verlag, 2019. http://d-nb.info/1180261550/34.

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5

Rehan, Naveed. "Rationalism and D. H. Lawrence : a 21st century perspective." Thesis, Montana State University, 2004. http://etd.lib.montana.edu/etd/2004/rehan/RehanN04.pdf.

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Since the time of the Greek philosopher Plato, Western intellectuals have relied on logos or \"the word\" to make philosophical propositions about the world humans find themselves in. Logos or \"the word\" has generally been privileged over mythos or pathos, denoting emotion and feeling. This privileging has sometimes been challenged by intellectuals within the Western tradition. D. H. Lawrence was the most vocal and passionate writer to do so in modern times. This text traces the development of rationalism in the Western tradition and Lawrence\'s resistance to it. It also examines modern theoretical developments and notes their convergence with Lawrence\'s ideas. It concludes by claiming that the postmodern intellectual climate in the West tends towards a critique of rationalism, much like Lawrence.
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Wisner, Alexander S. "A Thesis Entitled The Evaluation of Neurotrophic Factor’s Ability to Prevent Induced Cell Death in a PC12 Cell Based Huntington’s Disease Model." University of Toledo Health Science Campus / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=mco1438346174.

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Motlhamme, Moitheki Zephorah. "Tlhotlhomisi ya dintshontsho tsa lorato : L. D. Raditladi." Pretoria : [s. n.], 2005. http://upetd.up.ac.za/thesis/available/etd-11062007-115555.

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8

Bocek, Thomas. "PeerCollaboration a peer-to-peer collaboration application for large-scale systems ; [doctoral thesis]." Aachen Shaker, 2010. http://d-nb.info/1002791103/04.

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9

Peinl, Hannes [Verfasser]. "Essays on mitigation options: Forestry, CCS and Renewable Energy : PhD Thesis / Hannes Peinl." Berlin : epubli GmbH, 2015. http://d-nb.info/1072596180/34.

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Heywood, Peta, and P. Heywood@latrobe edu au. "BREAKING THE MIND-FORG�D MANACLES : a study of adolescent transformation." La Trobe University, 2003. http://www.lib.latrobe.edu.au./thesis/public/adt-LTU20081210.150230.

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This study has adopted the metaphor of �mind-forged manacles� to explore adolescent transformation within an educational context. It does this by examining the experiences of two groups of people who participated in an intensive, one-off personal development program for adolescents, known as Discovery. The first study involves secondary school students for whom the program was part of the school curriculum. The second study consists of an older group of people who did the program during their adolescence and outside the formal education system. The third study is a contemplation of transformation derived from my experience as researcher during the course of completing this thesis. In an attempt to reflect the perspectival worldview from within which the study is created I have drawn on a range of theorists. To integrate their ideas I created three different �lenses� or ways of viewing the data. The first lens is developed from consciousness theory, the second from process philosophy and complex self-organising systems theory, and the third from individual humanistic psychology. The educational pedagogy is holistic and embraces developmental models of thinking and learning. The study uses participant reflection to argue that a program of intentionally focussed challenges, combined with the support that enables these challenges to be successfully met, can be transformational for many young people. It suggests that the complex postmodern world requires teachers to be aware of their own and their students� consciousness, and demands learning experiences that are deliberately focussed on helping the process of consciousness transformation rather than only on achieving predetermined outcomes. Transformation is understood as a shift to a different order of consciousness in which it is how one sees rather than what one sees that changes. With each shift towards a new order of consciousness the mind-forged manacles are loosed and individuals accept increasing responsibility for their lives and how they live them. Educational programs can be developed to assist this process.
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11

Molema, Matlho Segopotso. "Improving meat tenderness with vitamin D₃ and electrical stimulation." Pretoria : [s.n.], 2008. http://upetd.up.ac.za/thesis/available/etd-09222008-124203.

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12

Bakalis, Nikolaos [Verfasser]. "Philosophical and Historical Dimensions of Charles S. Peirce’s Self-Corrective Thesis (SCT) / Nikolaos Bakalis." Wuppertal : Universitätsbibliothek Wuppertal, 2011. http://d-nb.info/1009494783/34.

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13

Packer, Robert R. "The effect of d-amphetamine on habituation of schedule controlled operant behavior." Online access for everyone, 2008. http://www.dissertations.wsu.edu/Thesis/Summer2008/r_packer_070808.pdf.

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Kusnaman, Djeimy. "Development planning and project cycle analysis for sericulture in Central Java : case study: Banyumas Sutera Alam (BSA), Kaliori-Banyumas, Central Java /." Saarbrücken : VDM, 2008. http://d-nb.info/988874725/04.

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Grobbelaar, Sara Susanna. "R&D in the national system of innovation a system dynamics model /." Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-07212007-130132.

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Brinkjost, Tobias [Verfasser], Petra [Akademischer Betreuer] Mutzel, and Daniel [Gutachter] Rauh. "Seconds first! : A thesis dedicated to secondary structure elements / Tobias Brinkjost ; Gutachter: Daniel Rauh ; Betreuer: Petra Mutzel." Dortmund : Universitätsbibliothek Dortmund, 2019. http://d-nb.info/1205156798/34.

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17

Maša, Vojtěch. "Vysokoškolská kvalifikační práce:ATELIÉROVÁ ČÁST (D)." Master's thesis, Vysoké učení technické v Brně. Fakulta výtvarných umění, 2016. http://www.nusl.cz/ntk/nusl-240602.

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In my diploma thesis, which is called "University Qualification Thesis: MASTER'S DEGREE DIPLOMA THESIS - STUDIO PART (D), I try to fulfill the protocol, which is specified in the following points: - Get grade "D" from my diploma thesis - studio part, - If I don't get grade "D" from my diploma thesis - studio part, I did not fulfill the assignment and the goal. Therefore, the project should not be considered as successful and should be graded "F". The thesis doesn't have a visual form. The project itself is just the "concept" described in the two points mentioned above in the text including all the consequences and its progression. My creative contribution is only to induce the situation. This text is just a text part of the documentation used for easier understanding and for contextualizing. Thus, this text is a lexical (and graphical in case of the diagram shown in the full text) comment on the project and it should not be subject to evaluation. Additional form of documentation of the project will be an audio recording of defense of this project taken by a record company. My speech during the defense is also not meant to be a performace as an art discipline and therefore should not be assessed.
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18

Dancer, Michael William. "Analysis of the theta-D filter as applied to hit-to-kill interceptors and satellite orbit determination." Diss., Rolla, Mo. : Missouri University of Science and Technology, 2010. http://scholarsmine.mst.edu/thesis/pdf/Dancer_09007dcc807855a7.pdf.

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Thesis (M.S.)--Missouri University of Science and Technology, 2010.
Vita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed April 7, 2010) Includes bibliographical references (p. 70-77).
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19

Schmidt, Michaela. "How to manage your PhD thesis : development of a process model of self-regulation to foster postgraduate students /." Hamburg : Kovač, 2009. http://d-nb.info/996716505/04.

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Van, Zyl Anthea. "Drivers of knowledge transfer between universities and industry R & D partners in South Africa." Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-04102008-131307.

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Germer, Thomas. "Beschaffungsauktionen : theoretische Grundlagen und empirische Befunde aus Europa und den USA /." Frankfurt am Main : Europ. Management Publications, 2008. http://d-nb.info/987199250/04.

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Kotula, Martin [Verfasser]. "Development of a Risk-Oriented Strategic Sourcing (ROSS) Framework for the Construction and Electronics Manufacturing Industries : Doctorate Thesis / Martin Kotula." Berlin : epubli GmbH, 2016. http://d-nb.info/1081863811/34.

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23

Pastor, Patrick A. "A theoretical study of anomeric methyl glycosides separated by ion mobility spectrometry : the sodium adducts of alpha- and beta-methyl-D-mannopyranoside." Online access for everyone, 2007. http://www.dissertations.wsu.edu/Thesis/Summer2007/p_pastor_051807.pdf.

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Louw, Reinier Willem. "Die bydrae van Dr J.D. [Koot] Vorster tot die kerkregtelike ontwikkeling van die Ned Geref Kerk met besondere verwysing na die kerkverband en sy aandeel in die totstandkoming van die Algemene Sinode in 1962 /." Pretoria : [s.n.], 2009. http://upetd.up.ac.za/thesis/available/etd-09252009-015827/.

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Harnasch, Rüdiger. "Kooperatives Informations- und Knowledge-Management in wissensintensiven Anwendungsfeldern am Beispiel des technischen Service /." Hamburg : Kovač, 2008. http://d-nb.info/987714791/04.

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Mach, Holger. "Steuerliche Risiken bei der Übertragung von Anteilen an Kapitalgesellschaften /." Norderstedt : Books on Demand, 2008. http://d-nb.info/988204940/34.

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Pyhel, Jörn. "Gewerkschaftliche Mitgliedschaftsloyalität : eine empirische Analyse der IG-Metall-Mitgliederbindung in der Fahrzeugindustrie und im Maschinenbau /." Kassel : Kassel Univ. Press, 2008. http://d-nb.info/988737167/04.

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Sperlich, Andrea. "Theorie und Praxis erfolgreichen Managements privater Hochschulen in Deutschland /." Berlin : BWV, 2008. http://d-nb.info/989302423/04.

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Kraft, Mirko. "Kostentransparenz in Versicherungsunternehmen durch Deckungsbeitragsrechnungen : Controlling als informatorische Basis der Steuerung von Komposit-Versicherungsunternehmen /." Karlsruhe : Verl. Versicherungswirtschaft, 2008. http://d-nb.info/988074826/04.

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Cartwright, Justin Adam. "A novel technique for harmonic cancellation in class D amplifiers a thesis presented to the faculty of the Graduate School, Tennessee Technological University /." Click to access online, 2009. http://proquest.umi.com/pqdweb?index=2&did=1759989201&SrchMode=1&sid=1&Fmt=6&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1250263495&clientId=28564.

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Böhm, Thomas [Verfasser]. "Reassessing the convergence thesis. An analysis of the 2018/2019 Corporate Governance Codes of the United Kingdom and Germany / Thomas Böhm." München : GRIN Verlag, 2019. http://d-nb.info/1199192457/34.

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Hasan, Mohammed. "The filtration and oxidation characteristics of a diesel oxidation catalyst and a catalyzed particulate filter : development of a 1-D 2-layer model /." Available online. Click here, 2005. http://sunshine.lib.mtu.edu/ETD/THESIS/hasanm/Thesis.pdf.

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Karhan, Kristof [Verfasser]. "Energetics and chemistry of hydrogen bonds in water and at the surface : thesis to aquire the title Doktor der Naturwissenschaften / Kristof Karhan." Paderborn : Universitätsbibliothek, 2018. http://d-nb.info/1156920434/34.

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Zitzmann, Thomas. "Kollektive Leistungen von Wirtschaftsverbänden : Planung und Lenkung anhand eines phasenorientierten Qualitätsmodells /." Wiesbaden : Gabler, 2008. http://d-nb.info/987655760/04.

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Dannhauser, Estelle Henrietta. "Jesus the prophet maps and memories /." Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-09292006-135199/.

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Rager, Markus. "Energieorientierte Produktionsplanung : Analyse, Konzeption und Umsetzung /." Wiesbaden : Betriebswirtschaftlicher Verl. Gabler, 2008. http://d-nb.info/986403091/04.

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Gossy, Gregor. "A stakeholder rationale for risk management : implications for corporate finance decisions /." Wiesbaden : Gabler, 2008. http://d-nb.info/987653415/04.

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Niebergall, Jörg. "Wertgenerierung durch Corporate Hedging : eine empirische Untersuchung der internationalen Automobilindustrie /." Lohmar [u.a.] : Eul, 2008. http://d-nb.info/987951793/04.

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Stingel, Susanne. "Tarifwahlverhalten im Business-to-Business-Bereich : eine empirisch gestützte Analyse am Beispiel Mobilfunktarife /." Wiesbaden : Gabler, 2008. http://d-nb.info/987831844/04.

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Besse, Daniel. "Die Bewertung von IT-Projekten : eine empirische Analyse anhand der Finanzdienstleistungsbranche /." Norderstedt : Books on Demand, 2008. http://d-nb.info/988347024/04.

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Schuhen, Michael. "Führungsnachwuchs mit System : Planung und Gestaltung einer Lernumgebung für Trainee-Programme /." Marburg : Tectum Verl, 2008. http://d-nb.info/987198998/04.

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Hinne, Carsten. "Mergers & Acquisitions Management : Bedeutung und Erfolgsbeitrag unternehmensinterner M & A-Dienstleister /." Wiesbaden : Betriebswirtschaftlicher Verl. Gabler, 2008. http://d-nb.info/987455699/04.

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Wu, Jianqing. "Structural Study of eIF Complexes by H/D Exchange FT-ICR Mass Spectrometry." Palaiseau, Ecole polytechnique, 2013. https://pastel.hal.science/docs/00/91/40/13/PDF/thesis-print-WU.pdf.

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Le complexe d'initiation de la traduction 3 des eucaryotes (eIF3) joue un role central dans le réseau d'interaction des divers facteurs d'initiation de la traduction qui s'assemblent sur les ribosomes 40S, et participent aux différentes réactions au cours de la voie d'initiation de la traduction. Chez Saccharomyces cerevisiaea, ce complexe est composé de cinq sous-unités, qui sont toutes homologues avec les sous-unités de cœur du complexe eIF3 des mammifères, composé de 13 sous-unités. Un objectif majeur actuellement est d'obtenir une structure tridimensionnelle de ce complexe. Dans une première étape vers la résolution de cette structure, les efforts portent sur la détermination des régions de liaisons entre sous-unités, dont assez peu sont actuellement connues. La région d'interaction entre la sous-unité 3i et le domaine C-terminal extrémal de 3b a récemment été résolu par RMN et structure cristallographique. D'un autre côté, la région d'interaction entre 3i et 3g, bien que localisée à l'extrémité N-terminale de 3g, doit encore être précisée. Les échanges hydrogène/deutérium (HDX) se sont développés depuis les années 1990 comme outil d'analyse structurale de protéines et de complexes multiprotéiques. La spectrométrie de masse est couramment utilisée pour réaliser la mesure de l'échange. L'approche HDX la plus usuelle repose sur une mesure de masse de peptide marqués issus d'une digestion enzymatique des protéines d'intérêt afin de déterminer le contenu en deutérium ainsi que leur vitesse d'incorporation. Pour ce travail, un spectromètre de masse à ultra-haute résolution, de type FT-ICR 7T, a été utilisé conjointement avec une séparation nano-LC pour générer des données HDX-MS de haute qualité. La précision de mesure de masse d'un spectromètre de masse FT-ICR n'est pas suffisante en elle-même pour identifier de façon certaine les peptides issus d'une digestion à la pepsine, du fait de l'absence de spécificité de la pepsine. Nous avons en conséquence développé une approche statistique pour l'identification des peptides, en se basant sur la définition d'une valeur de probabilité d'occurrence pour un peptide donné dans une digestion à la pepsine. En combinaison avec la précision élevée sur la mesure de masse, ce seul critère permet une identification efficace des peptides, sans devoir recourir à une validation par MS/MS systématique. Cette méthode a été mise en application pour l'étude des régions de liaison dans les complexes eIF3i :b et eIF3i :g. Dans les deux cas, 3i a été surexprimée sous sa forme complète. Au contraire, pour 3b et 3g, seul un segment partiel de la protéine native, contenant le domaine présumé d'interaction a été surexprimé. La liste de référence des peptides présents permet une excellente couverture de séquence et une forte superposition entre séquences adjacentes, ce qui assure une élucidation de la structure avec une bonne résolution spatiale. Pour la liaison entre 3i et 3b, les régions d'interactions qui sont apparues dans des conditions en solution proches des conditions physiologiques sont cohérentes avec la structure proposée par une autre équipe au cours de la thèse, apportant des informations complémentaires à celles issues de la structure cristallographique dérivée de la phase solide. Pour la liaison entre 3i et 3g, la région d'interaction a été étudiée en l'absence de toute donnée structurale à l'échelle atomique pour 3g. Les résultats apportent une vision nouvelle sur la formation du complexe entre 3g et 3i, et pour la première fois les régions de liaisons exacts ont été mis en évidence
The eukaryotic initiation factor 3 (eIF3) complex plays a core role in the interaction network among several eIFs that assemble on the 40S ribosomes and participate in the different reactions throughout the translation initiation pathway. The Saccharomyces cerevisiaea eIF3 complex comprises five subunits, all of which are the core subunits of the mammalian eIF3 complex consisting of 13 subunits. Attempts to decipher its tridimensionnal structure are under way. A first path to study the structure of this complex is to complete the identification of binding regions, few of which are currently known. Recently, the interaction region between eIF3i and extreme C-terminal domain of eIF3b has been obtained through NMR and crystal structure. On the other hand, the interaction region between 3i and 3g, although located to the N-terminal domain of 3g still remains to be defined. Hydrogen/deuterium exchanges (HDX) have been developed for a long time and are widely used for structural studies of proteins and multiprotein complexes. It is commonly analyzed using mass spectrometry. The most classic standard HDX-MS approach consists in making a mass measurement of deuterium-labelled peptides from an enzymatic digestion of the protein of interest to determine the level and rate of deuterium incorporation. In this study, a high performance 7 T FT-ICR mass spectrometer was used in combination with nanoLC separation to acquire highly accurate HDX-MS data. The precision on the mass measurement of FT-ICR MS is by itself not sufficient to unambiguously identify peptides from a pepsin digest due to the lack of pepsin specificity. We therefore developed a statistical approach for peptide identification, based on a probability of occurrence value of a given peptide within a pepsin digest. In combination with high mass accuracy, this method allows efficient identification of the peptides, without additional need of MS/MS verification. This method has been applied on the study of the binding regions in the complexes of eIF3i:bC3 and eIF3i:gC1ΔC. Peptide reference lists with high sequence coverage and rich sequence superposition ensured structure elucidation with high spatial resolution. For the binding of 3i and 3b, the detailed interaction regions were unveiled for proteins in the solution phase which resembled the physiological condition and were coherent with the reported protein structure, thus provided complimentary information to the crystallographic structure in solid phase. For the binding of 3i and 3g, the interaction regions were studied with the absence of any atomic structural information of 3g. This provides significant insights of the complex formation of 3i and 3g, and for the first time the precise binding regions were successfully revealed
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Wittkowski, Ansas. "Grenzüberschreitende Verlustverrechnung in Deutschland und Europa : eine ökonomische, europa- und verfassungsrechtliche Analyse /." Wiesbaden : Gabler, 2008. http://d-nb.info/987989618/04.

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Pelz, Richard. "Anzeigenmarketing im Verlag : eine empirische Analyse der Marketingressourcen und Marketingkompetenzen im Anzeigenmarketing von Zeitschriftenverlagen /." Wiesbaden : Gabler, 2008. http://d-nb.info/986294357/04.

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Tillenburg, Stefan. "Das Konzept der ausbalancierten Produktion in Supply Chains /." Wiesbaden : Betriebswirtschaftlicher Verlag Gabler, 2008. http://d-nb.info/986749842/04.

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Hungeling, Stephan. "Ressourcenbasierter Vertrieb in jungen Technologieunternehmen /." Wiesbaden : Gabler, 2008. http://d-nb.info/985030216/04.

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Dittmer, Keren Elizabeth. "Inherited rickets in Corriedale sheep : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University, Palmerston North, New Zealand." Massey University, 2008. http://hdl.handle.net/10179/882.

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Inherited rickets of Corriedale sheep is a newly discovered skeletal disease of sheep with simple autosomal recessive inheritance. The clinical signs resemble rickets in other species and include decreased growth rate, thoracic lordosis and angular limb deformities. Radiographic features include physeal thickening, blurred metaphyseal trabeculae and thickened porous cortices. Computed tomography scanning of long bones reveals increased bone mineral content and cortical area, but decreased bone mineral density. Gross lesions include segmental thickening of physes, growth arrest lines, collapse of subchondral bone of the humeral head, thickened cortices and enthesophytes around distal limb joints. Microscopically there is persistence of hypertrophic chondrocytes at sites of endochondral ossification, inappropriate and excessive osteoclastic resorption, microfractures and wide, unmineralised osteoid seams lining trabeculae and filling secondary osteons. Affected sheep are persistently hypophosphataemic and hypocalcaemic. Normal serum 25-hydroxyvitamin D3 concentration accompanied by a two-fold elevation in 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) suggested a defect in endorgan responsiveness to vitamin D as a likely mechanism, but this was not supported by in vitro studies using cultured skin fibroblasts. These studies revealed normal vitamin D receptor function and the presence of 24- hydroxylase mRNA in cells from affected sheep, even without induction by 1,25(OH)2D3. Inappropriate overexpression of 25-hydroxyvitamin D3-24- hydroxylase, the enzyme that breaks down active vitamin D, is therefore considered the probable cause of inherited rickets in Corriedale sheep. Such a mechanism has not previously been described as a cause of inherited rickets in humans or other animal species. Treatment of affected sheep with high oral doses of vitamin D3 weekly for 3 months showed a trend towards increased bone mineral density, thus supporting an intact vitamin D receptor. Preliminary studies on immune function revealed reduced numbers of CD4+ and CD8+ lymphocytes and reduced interferon-? production by lymphocytes stimulated with parasite antigen. This new form of inherited rickets may be widespread in
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49

Augeraud, Michel. "Systel-D : un modèle et une méthode d'analyse et de conception des systèmes de communication prenant en compte leurs aspects dynamiques." Poitiers, 1989. http://www.theses.fr/1989POIT2263.

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L'objectif est la definition d'un modele et d'une methode d'etude au niveau logique d'un systeme de communication prenant en compte l'ensemble des aspects qui caracterisent les liaisons de communication et plus particulierement leur aspect dynamique. Le modele repose, pour traduire l'aspect dynamique, sur une representation discrete du fonctionnement observe a un niveau macroscopique
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Honold, Frank. "Auswirkungen demotivierter Mitarbeiter auf den finanziellen Unternehmenserfolg /." Hamburg : Kovač, 2008. http://d-nb.info/988363151/04.

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