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Dissertations / Theses on the topic 'D. Landreth and Co'

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Published: 12 December 2022
Last updated: 26 January 2023

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1

Ulbrich, Till. "Co, Pd- und Co, Pt-Schichtsysteme auf Partikelmonolagen." Berlin dissertation.de, 2008. http://d-nb.info/989281876/04.

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2

Köpke, Daniel [Verfasser]. "Verfahrenstechnik der CO₂-Abscheidung aus CO₂-reichen Oxyfuel-Rauchgasen / Daniel Köpke." München : Verlag Dr. Hut, 2011. http://d-nb.info/1013526465/34.

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3

Thönnißen, Carsten [Verfasser], and Hans Peter [Akademischer Betreuer] Oepen. "Magnetische Eigenschaften von einzelnen Co/Pt- und Co-Nanostrukturen / Carsten Thönnißen ; Betreuer: Hans Peter Oepen." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2019. http://d-nb.info/1188818643/34.

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4

Schröder, Henning [Verfasser], and Alexander [Akademischer Betreuer] Föhlisch. "Ultrafast electron dynamics in Fe(CO)5 and Cr(CO)6 / Henning Schröder ; Betreuer: Alexander Föhlisch." Potsdam : Universität Potsdam, 2016. http://d-nb.info/1218400765/34.

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5

Detert, Thorben. "Low complexity co-channel interference cancellation." Göttingen Sierke, 2008. http://d-nb.info/991223314/04.

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6

Rothhardt, Philip [Verfasser], and Eicke [Akademischer Betreuer] Weber. "Co-diffusion for bifacial n-type solar cells = Co-Diffusion für bifaziale Solarzellen aus n-dotiertem Silizium." Freiburg : Universität, 2014. http://d-nb.info/1123481741/34.

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7

Heße, Simon [Verfasser], and Hans Peter [Akademischer Betreuer] Oepen. "Magnetotransport in Co/Pt-Schichtsystemen und Charakterisierung einzelner Co/Pt-Nanoteilchen / Simon Heße. Betreuer: Hans Peter Oepen." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2014. http://d-nb.info/1054421684/34.

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8

Whitecross, Angela Frances. "Co-operative Commonwealth or New Jerusalem? : the Co-operative Party and the Labour Party, 1931-1951." Thesis, University of Central Lancashire, 2015. http://clok.uclan.ac.uk/11485/.

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The Co-operative Party, despite representing the largest consumer and social movement in Britain, is systematically overlooked or misunderstood in twentieth century British political historiography. What makes this neglect more surprising is that from 1927 the Co-operative Party had a formal electoral agreement with the Labour Party, the basis of which remains in place today. Through this agreement the two parties agreed to work together to return joint Co-operative-Labour candidates in certain constituencies. This unique political alliance reflected a shared ideological ground between the two parties, united in their aim to displace capitalism with common ownership. However, despite this common aim, the methods through which this would be achieved varied and whilst the Labour Party focused on state ownership as key to the ‘socialist commonwealth’, the Co-operative Party, as the political arm of theco-operative movement embodied the ideal of a‘co-operative commonwealth’ built on the principles of democratic voluntary association. Historians who have addressed the relationship between the Labour Party and the co-operative movement have argued that co-operative methods of ownership were systematically marginalised, overlooked and ignored by the Labour Party, particularly during the 1945 to 1951 period of Labour Government. In this context, this thesis will examine the political relationship between the Co-operative Party and the Labour Party in the broader period from 1931 to 1951. It will argue that both organisational and ideological factors contributed to the invisibility of co-operative methods of ownership in the policies of the Labour Party. Moreover, this will provide an additional perspective to debates regarding the development of the Labour Party during the 1930s and over the future direction of nationalisation post 1945. Despite its marginality the Co-operative Party represented a large body of working class consumers and a significant business organisation, which straddled both the labour movement and co-operative movement. Whilst this thesis agrees that co-operative ideas of ownership remained a minor influence on the Labour Party throughout this period, it will nevertheless argue that Co-operative Party contributions to policy discussions provide an alternative perspective from which a growing recognition of the diversity of influences on the Labour Party can be explored. In doing so this thesis will also provide an original interpretation of the organisational and policy history of the Co-operative Party. This will highlight tensions not only with the Labour Party, but also within the co-operative movement with regards to the function and purpose of the Co-operative Party - and more significantly the role of the co-operative movement in a socialist society.
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9

Kloodt-Twesten, Fabian [Verfasser], and Hans Peter [Akademischer Betreuer] Oepen. "Dzyaloshinskii-Moriya-Wechselwirkung epitaktisch gewachsener Co/Ir- und Co/Pt-Grenzflächen / Fabian Kloodt-Twesten ; Betreuer: Hans Peter Oepen." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2020. http://d-nb.info/1218688483/34.

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10

Westmeier, Regina [Verfasser]. "Inhalative Kombinationspräparate durch Co-Präzipitation / Regina Westmeier." Kiel : Universitätsbibliothek Kiel, 2008. http://d-nb.info/101966214X/34.

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11

Salisch, Nadine Christina. "Roles of co-stimulatory and co-inhibitory receptor expression in T cell dysfunction in HIV-1 and SIV infection." kostenfrei, 2010. http://d-nb.info/1002589851/34.

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12

Böhnert, Tim [Verfasser], and Kornelius [Akademischer Betreuer] Nielsch. "Magneto-thermopower and Magnetoresistance of Co-Ni Alloy and Co-Ni/Cu Multilayered Nanowires. / Tim Böhnert. Betreuer: Kornelius Nielsch." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2014. http://d-nb.info/1052996698/34.

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13

Pöttinger, Leo [Verfasser], and Thomas [Akademischer Betreuer] Bürgi. "Spectroscopic characterization of dye sensitized TiO₂ with CO₂ co-adsorption and visible light excitation / Leo Pöttinger ; Betreuer: Thomas Bürgi." Heidelberg : Universitätsbibliothek Heidelberg, 2014. http://d-nb.info/1177810808/34.

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14

Edzang, Edzang Regis Donatien [Verfasser], and G. [Akademischer Betreuer] Schaub. "Kobalt-basierte Fischer-Tropsch Synthese und CO-Konvertierung für CO-reiche Synthesegase / Regis Donatien Edzang Edzang. Betreuer: G. Schaub." Karlsruhe : KIT-Bibliothek, 2015. http://d-nb.info/1074463803/34.

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15

Romanski, Steffen [Verfasser]. "Synthese und Evaluation geschützter oxysubstituierter Dien-Fe(CO)3-Komplexe als enzymatisch aktivierbare CO-freisetzende Moleküle (ET-CORMs) / Steffen Romanski." München : Verlag Dr. Hut, 2013. http://d-nb.info/1033041610/34.

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16

Sazonov, Andrew P. [Verfasser], and Gernot [Akademischer Betreuer] Heger. "Peculiarities of crystal and magnetic structures of synthetic Co-olivine, Co 2 SiO 4 / Andrew P. Sazonov ; Betreuer: Gernot Heger." Aachen : Universitätsbibliothek der RWTH Aachen, 2009. http://d-nb.info/1129691535/34.

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17

Friedrich, Markus [Verfasser]. "Parallel Co-Simulation for Mechatronic Systems / Markus Friedrich." München : Verlag Dr. Hut, 2012. http://d-nb.info/1021072753/34.

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18

Sieber, Christina [Verfasser]. "Characterization of a BMP co-receptor / Christina Sieber." Berlin : Freie Universität Berlin, 2010. http://d-nb.info/1024334643/34.

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19

Wurzinger, Olaf [Verfasser]. "CO-Sensorik in H2-reichen Gasen / Olaf Wurzinger." Aachen : Shaker, 2004. http://d-nb.info/1172615217/34.

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20

Mostertz, Philip [Verfasser]. "Die UG (haftungsbeschränkt) & Co. KG / Philip Mostertz." Baden-Baden : Nomos Verlagsgesellschaft mbH & Co. KG, 2014. http://d-nb.info/1107609267/34.

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21

Winkler, Gerrit [Verfasser], and Hans Peter [Akademischer Betreuer] Oepen. "Korrelation zwischen strukturellen und magnetogalvanischen Eigenschaften von Pt/Co/Pt- und Pd/Co/Pd-Schichtsystemen / Gerrit Winkler. Betreuer: Hans Peter Oepen." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://d-nb.info/1081768096/34.

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22

Austgen, Michael [Verfasser]. "Serielles Co-Sputtern : Entwicklung einer flexiblen Beschichtungstechnologie und deren Charakterisierung am Beispiel der Ratenerhöhung von Metalloxiden durch Co-Dotierung / Michael Austgen." Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2011. http://d-nb.info/101818323X/34.

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23

Petry, Ina [Verfasser], and Claudia S. [Akademischer Betreuer] Leopold. "Novel formulation techniques for co-amorphous systems with special focus on in situ co-amorphisation / Ina Petry ; Betreuer: Claudia S. Leopold." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2019. http://d-nb.info/1200102010/34.

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24

Winkler, Gerrit Verfasser], and Hans Peter [Akademischer Betreuer] [Oepen. "Korrelation zwischen strukturellen und magnetogalvanischen Eigenschaften von Pt/Co/Pt- und Pd/Co/Pd-Schichtsystemen / Gerrit Winkler. Betreuer: Hans Peter Oepen." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://d-nb.info/1081768096/34.

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25

Bailey, Daniel. "High pressure studies of d-block thioether co-ordination complexes." Thesis, University of Nottingham, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594819.

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26

Huang, Zhida [Verfasser]. "Characterization and catalytic activity study of SBA-15-supported MoO3, MoS2, Ni or Co promoted MoS2 and Co promoted WS2 / Zhida Huang." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/1019951621/34.

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27

Schuster, Cornelia [Verfasser]. "Regulation of CD8 T cell-mediated diabetes induction by co-inhibitory and co-stimulatory signals delivered by pancreatic beta cells / Cornelia Schuster." Ulm : Universität Ulm. Medizinische Fakultät, 2012. http://d-nb.info/1022896083/34.

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28

Klein, Holger [Verfasser]. "Co-occurrence of transcription factor binding sites / Holger Klein." Berlin : Freie Universität Berlin, 2010. http://d-nb.info/1024541517/34.

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29

Schubert, Andreas [Verfasser]. "Unternehmensmitbestimmung in der SE & Co. KGaA / Andreas Schubert." Baden-Baden : Nomos Verlagsgesellschaft mbH & Co. KG, 2018. http://d-nb.info/1160307652/34.

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30

Hürtgen, Stefanie. "Transnationales Co-Management : betriebliche Politik in der globalen Konkurrenz /." Münster : Westfälisches Dampfboot, 2008. http://d-nb.info/989325717/04.

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31

Kleining, Jochen. "M. Kempinski & Co. Die "Arisierung" eines Berliner Traditionsunternehmens." Hamburg Diplomica-Verl, 2007. http://d-nb.info/989621170/04.

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32

Vollan, Björn. "Co-operation for common pool resources an experimental perspective." München Verl. Dr. Hut, 2009. http://d-nb.info/992892228/04.

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33

Ferrari, Arianna. "Genmaus & Co gentechnisch veränderte Tiere in der Biomedizin." Erlangen Fischer, 2006. http://d-nb.info/987294555/04.

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34

Pongsakornrungsilp, Siwarit. "Value co-creation process : reconciling S-D logic of marketing and consumer culture theory within the co-consuming group." Thesis, University of Exeter, 2010. http://hdl.handle.net/10036/113457.

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The purpose of this dissertation is to demonstrate how individual consumers negotiate in the collective community in order to co-create value. By making use of the concepts of ‘resources’ from the Service Dominant Logic of Marketing and ‘cultural lens’ from Consumer Culture Theory, this dissertation considers both individual and collective interaction in order to demonstrate the roles of individual consumers in the value creation process and how the value creation process works. A comprehensive and up to date review of literature provides a guide to the theory and a path for research. This dissertation employed netnography to understand social and cultural aspects of consumption from an online football fan community. The data collection also included participant and non-participant observations, and local fans interviewings. Hermeneutical framework of interpretation was used to analyse data. The findings show that consumers can co-create value among themselves through the roles of ‘provider’ and ‘beneficiary’. It shows the dynamic movement of individual consumers within the continuous learning process of value creation. This dissertation demonstrates that brand community plays a role as a platform of value creation. Consumers can co-create value among themselves through the process of engaging, educating and enriching. The finding demonstrates active roles of consumers in value creation process. This dissertation also discusses how inequalities between resources of consumers in brand community can cause conflicts among them and how these conflicts stimulate consumers to co-create the collective resources. Within this process, consumers have collectively balanced the power through the social interaction in order to eliminate the domination and conflicts. This dissertation extends the previous researches in value creation within brand community by demonstrating how individual consumers engage and negotiated in value creation process. It contributes to respond working consumers and double exploitation through ‘sacrifice’.
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35

Bekker, Viacheslav [Verfasser]. "Entwicklung neuartiger thermisch stabiler weichmagnetischer Fe-Co-Al-N- und Fe-Co-Ta-N-Dünnschichtmaterialien für Hochfrequenzanwendungen / Forschungszentrum Karlsruhe GmbH, Karlsruhe. Viacheslav Bekker." Karlsruhe : FZKA, 2005. http://d-nb.info/977281507/34.

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36

Baga, Lukman Mohammad [Verfasser], and Michael [Akademischer Betreuer] Kirk. "Co-operative Entrepreneurs and Agribusiness Development : A Study Towards the Development of Agribusiness Co-operatives in Indonesia / Lukman Mohammad Baga. Betreuer: Michael Kirk." Marburg : Philipps-Universität Marburg, 2013. http://d-nb.info/1044395621/34.

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37

Scheiblich, Hannah Christina [Verfasser]. "Nitric oxide (NO)- and carbon monoxide (CO)-mediated signal transduction in a co-culture system of microglia and human model neurons / Hannah Christina Scheiblich." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2015. http://d-nb.info/108086783X/34.

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38

Oliveira, Marcos César de. "Exploring the use of co-change clusters in software comprehension tasks." reponame:Repositório Institucional da UnB, 2015. http://dx.doi.org/10.26512/2015.09.D.22533.

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Dissertação (mestrado)—Universidade de Brasília, Instituto de Ciências Exatas, Departamento de Ciência da Computação, 2015.
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O desenvolvimento de software orientado a características (FOSD) é um paradigma que pode ser usado, entre outros, para estruturar um sistema de software em torno de características que podem representar pequenas funcionalidades do software bem como requisitos não funcionais. Além do seu papel na estruturação do software, o uso de FOSD habilita a ativação e desativação de features individuais em uma dada configuração de software. Essa vantagem pode ser útil em cenários onde a variabilidade do software é necessária. Por outro lado, a adoção da abordagem FOSD pode ser feita em um sistema de software existente, torna-se necessária a aplicação de alguma técnica de engenharia reversa para extração de features de uma base de código legada, bem como o mapeamento dessas features para suas implementações. Essa dissertação apresenta uma nova abordagem para auxiliar nessa atividade de engenharia reversa, a qual relaciona dados históricos extraídos de sistemas de controle de tarefas de desenvolvimento e de mudanças em código-fonte. A abordagem se baseia em técnicas de Mineração de Repositórios de Software (MSR), especificamente o agrupamento baseado em dependências evolucionárias entre elementos do código-fonte, que leva ao descobrimento de grupos de co-mudança. Assim, o objetivo deste trabalho é descobrir as propriedades dos grupos de co-mudança que podem ser úteis no processo de extração de features. Especificamente, um conjunto de termos, associados com os grupos, que revelam conceitos que podem ajudar a identificar features. De acordo com os resultados obtidos, os grupos de co-mudança não possuem vantagem quando usa- dos como unidades de modularização, mas podem revelar novas dependências que são ocultas ao desenvolvedor. Também mostram que os grupos de co-mudança possuem coesão conceitual, e que podem ser usados para extrair conceitos e termos associados com eles. Por fim, os conceitos extraídos dos grupos de co-mudança podem ser usados para construir um mapeamento entre eles e o código-fonte, e que podem ser usados como uma lista de sementes de entrada para métodos de expansão de features.
Feature-oriented software development (FOSD) is a paradigm that can be used, among others, to structure a software system around the feature concept that can represents small functionalities and non-functional requirements. Besides their role in software structure, FOSD enables the activation and deactivation of individual features in a given configuration of the software. This advantage can be useful in scenarios where the variability of the software is required. On the other hand, the adoption of FOSD can be done for an existing software system, thus, becomes necessary to apply some reverse engineering technique to extract features from a legacy code base, and also the mapping between these features and their implementations. This dissertation presents a new approach to aid in the reverse engineering activity, that relates historical data from issue tracking systems and source-code changes. The approach relies upon Mining Software Repositories (MSR) techniques, specifically the clustering based on co-evolutionary dependencies between source-code elements, which leads to the discover of co-change clusters. Thus, the goal of this work is to discover the properties of the co-change clusters that can be useful in a feature extraction process. Specifically, a set of terms, associated with the clusters, which reveal concepts that can help to identify features. According to the study results, co-change clusters have no advantage when used as a modular unit, but can reveal new dependencies that is hidden to the developer. They also show that the co-change clusters have conceptual cohesion, and can be used to extract concepts and the terms associated with them. In the end, the concepts extracted from co-change clusters can be used to build a mapping from them and the source-code, and that can be used as a input seed list to feature expansion methods.
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39

Koch, Miriam [Verfasser]. "Insights into co-translational protein quality control mechanisms / Miriam Koch." Konstanz : Bibliothek der Universität Konstanz, 2012. http://d-nb.info/1054602514/34.

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40

Sauther, Jens [Verfasser]. "Photoelektronenspektroskopische Untersuchungen an Metallphthalocyaninen auf Co/Cu(100) / Jens Sauther." Aachen : Shaker, 2010. http://d-nb.info/1080767215/34.

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41

Eckert, René [Verfasser], Ferdi [Gutachter] Schüth, and Martin [Gutachter] Muhler. "Mechanokatalytische CO-PROX / Rene Eckert ; Gutachter: Ferdi Schüth, Martin Muhler." Bochum : Ruhr-Universität Bochum, 2017. http://d-nb.info/1131354877/34.

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42

Salmen, David [Verfasser]. "Anwachsungsmodelle zur Umstrukturierung einer GmbH & Co. KG / David Salmen." Aachen : Shaker, 2013. http://d-nb.info/1050344898/34.

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43

Koch, Matthias. "Ökologische und ökonomische Bewertung von Co-Vergärungsanlagen und deren Standortwahl." Karlsruhe Univ.-Verl. Karlsruhe, 2009. http://d-nb.info/994167075/04.

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44

Haseborg, Wiebke ter. "Das Wettbewerbsverbot der Vorstandsmitglieder in der AG & Co. KG." Frankfurt, M. Berlin Bern Bruxelles New York, NY Oxford Wien Lang, 2009. http://d-nb.info/997724285/04.

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45

Messias, André Dutra. "Arcabouços de poli(L-co-D,L ácido láctico-co-trimetileno carbonato) para o crescimento de células osteoblásticas (SaOS-2)." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/263848.

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Orientador: Eliana Aparecida de Rezende Duek
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecânica
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Resumo: Polímeros a base de ácido láctico são largamente investigados como materiais para a engenharia tecidual. A capacidade de sofrer degradação hidrolítica, de ser reabsorvido pelo organismo e sua biocompatibilidade inerente, tornam-nos uma excelente escolha para tal aplicação. Entretanto, características como baixa flexibilidade e pequena capacidade de alongamento antes da fratura, tendem a limitar esses dispositivos em determinadas aplicações, o que pode ser melhorado com a adição de compostos que agem como plastificantes, como é o caso do trimetileno carbonato (TMC), quando presente na cadeia polimérica do copolímero de ácido láctico (PLDLA). O objetivo deste trabalho foi sintetizar e caracterizar o terpolímero de L-ácido láctico, D,L-ácido láctico e TMC, e obtenção de arcabouços para avaliação da viabilidade celular e atividade de células osteoblásticas (SaOS-2), em 1, 3, 7, 14 e 21 dias de cultivo, visando aplicação na engenharia tecidual óssea. Dessa forma, sintetizou-se o terpolímero a partir de 20 e 30% de TMC, através da polimerização em massa dos monômeros, como confirmado por RMN de 1H e 13C, utilizando como catalisador o Sn(Oct)2. A análise de GPC mostrou que os terpolímeros sintetizados apresentaram massa molar média (Mw) na ordem de 105 g/mol, característica importante que permite a obtenção de propriedades mecânicas mínimas para uma aplicação estrutural. A investigação térmica do PLDLA-TMC demonstrou uma discreta diminuição da Tg em relação ao PLDLA. Além disso, a degradação do terpolímero em etapa única iniciou-se em torno dos 290 ºC, como visto pelo TGA. O ensaio de MTT mostrou que o arcabouço de PLDLA-TMC permitiu um aumento na viabilidade celular, atingindo valores máximos em 7 dias, e mantendo-se estável até 14 dias de cultivo. Similarmente, a atividade de fosfatase alcalina foi crescente até 7 dias de cultivo, importante indicador da atividade osteoblástica. Esses resultados mostram que é possível produzir com sucesso o terpolímero PLDLA-TMC. Além disso, os arcabouços produzidos apresentaram características importantes considerando a aplicação para engenharia tecidual óssea
Abstract: Lactic acid based polymers are widely investigated as materials for tissue engineering. The ability to allow hydrolytic degradation, to be reabsorbed by the body and its inherent biocompatibility, make them an excellent choice for this application. However, characteristics such as low flexibility and low elongation ability before the fracture tend to limit these devices in particular applications, which can be enhanced with the addition of compounds that act as plasticizers, as the trimethylene carbonate (TMC) when present in the polymer chain of the copolymer of lactic acid (PLDLA). The objective of this work was to synthesize and characterize the terpolymer of L-lactic acid, D,L-lactic acid and TMC, obtain evaluation of scaffolds for cell viability and alkaline phosphatase activity of osteoblastic cells (SaOS-2) in 1, 3, 7, 14 and 21 days of culture, aiming its application in bone tissue engineering. Thus, the terpolymer is synthesized from 20 and 30% of TMC, by bulk polymerization of monomers, confirmed by 1H and 13C RMN. The GPC analysis showed that the copolymers synthesized showed average molar mass (Mw) in the order of 105 g/mol, an important feature that allows the attainment of minimum mechanical properties necessary for structural applications. The thermal investigation of thermal PLDLA-TMC showed a slight decrease of Tg comparing to PLDLA. Furthermore, the one step terpolymer degradation was initiated around 290 ºC, as shown by TGA. The MTT assay showed that the PLDLA-TMC scaffolds enabled an increase in cell viability, reaching a peak in 7 days, and remained stable until 14 days of cultivation. Similarly, the alkaline phosphatase activity was increased up to 7 days of culture, an important indicator of osteoblastic activity. These results show that it was possible to successfully produce a terpolymer from L-lactic acid, D,L-lactic acid and trimethylene carbonate. In addition, the scaffolds exhibited important characteristics considering the application for bone tissue engineering
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Materiais e Processos de Fabricação
Mestre em Engenharia Mecânica
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46

Fedrizzi, Vitor de Miranda. "Obtenção de dispositivos à base de poli(L-co-D,L ácido lático-co-trimetileno carbonato) para reparação de fraturas ósseas." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/263884.

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Orientador: Eliana Aparecida de Rezende Duek
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecânica
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Resumo: Polímero sintético biodegradável tem encontrado aplicações em diferentes áreas da medicina, especialmente em dispositivos ortopédicos. A principal vantagem desses materiais comparado com os materiais metálicos é pelo fato dos implantes biodegradáveis não necessitarem de uma segunda cirurgia para remover o dispositivo, resultando em baixo custo e menor risco para o paciente. Pinos de poli(L-co-D,L ácido lático-co-trimetileno carbonato), PLDLA-TMC, contendo 30% de TMC foram obtidos e caracterizados através do estudo in vitro e in vivo visando aplicação como dispositivos para fratura. Pinos de 2,5 mm de diâmetro foram obtidos por fusão do polímero e imersos em solução tampão fosfato, pH 7,4 para se estudar o processo de degradação in vitro e implantados na tíbia de ratos Wistars para avaliar a formação óssea após 15, 60, 90, 120 e 150 dias. Os resultados obtidos a partir do estudo da degradação in vitro de pinos PLDLA-co-TMC mostraram que as propriedades térmicas, mecânicas e morfológicas se mantêm praticamente inalteradas até 90 dias em solução tampão fosfato, especialmente temperatura de transição vítrea, módulo de Young, tensão máxima no alongamento e perda de massa, apesar da nítida variação da massa molar já no início do processo de degradação. Esses resultados corroboram com os do estudo in vivo, cujos resultados mostraram a ocorrência de neoformação óssea nos tempos iniciais, principalmente 60 e 90 dias, sendo que o grupo implante, no geral, apresentou uma formação óssea mais madura e organizada, com menor presença de fibrose do que o grupo controle. Esse conjunto de resultados indica que o material apresenta potencial para aplicado como dispositivo para recuperação de lesões ósseas, em situações onde seja adequada a permanência do implante durante longo período de tempo e ainda com a vantagem da degradação do mesmo, evitando sua posterior retirada
Abstract: Biodegradable synthetic polymers have found application in different areas of medicine, especially in orthopedics devices. The main advantage of these biomaterials compared to the metals materials is the fact of the use of biodegradable implants avoid the/necessity of a second surgery to removal the device, resulting in a lower costs and minor risks for the patient. Poly(L-co-D,L lactic acid-co-trimethylene carbonate), PLDLA-TMC, pins, content 30% of TMC were obtained and characterized by in vitro and in vivo study aiming application as fracture devices. Pins with 2,5mm of diameter were obtained by melting of polymer and immersed into the buffer phosphate solution, pH 7,4 to study in vitro degradation process and implanted in Wistars rats tibia to evaluate the bone formation after 15, 60, 90, 120 e 150 days. Results obtained from the in vitro degradation of the PLDLA-co-TMC pins showed that thermal, mechanical and morphological properties remained without alterations until 90 days, considering the glass transition temperature, Young modulus, maximum tension at the elongation and loss of mass. In spite of this, variation of molar mass was nitid since the initial of the degradation process. These results are in accordance with in vivo study, which showed the occurrence of bone neoformation in the initial times of implant, mainly after 60 and 90 days and presence of bone formation more organized and mature with minor presence of fibrosis than control group. These results are indicative that this material presents a potential to be applied as a device for recuperation of bone lesion in a situation where it is necessary the permanence of the implant for a long period of time and so with the advantage of the degradation, avoiding it to be removed
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Materiais e Processos de Fabricação
Mestre em Engenharia Mecânica
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47

Diefenbacher, Markus Elmar. "The transcriptional co-activator function of the LIM-domain protein nTrip6." Eggenstein-Leopoldshafen Forschungszentrum Karlsruhe GmbH, 2010. http://d-nb.info/1002907535/34.

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48

Srubar, Helena. "Ambivalenzen des Populären Pan Tau und Co. zwischen Ost und West." Konstanz UVK-Verl.-Ges, 2006. http://d-nb.info/986882399/04.

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49

Salzmann, Holger [Verfasser], and Bernd [Akademischer Betreuer] Fröhlich. "Collaboration in Co-located Automotive Applications / Holger Salzmann ; Betreuer: Bernd Fröhlich." Weimar : Professur Systeme der Virtuellen Realität, 2010. http://d-nb.info/1115342274/34.

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50

Wille, Ansgar [Verfasser]. "Untersuchungen zu laserinduzierten Adsorptionsplatzänderungen im Modellkatalysatorsystem CO/Pd/Al2O3 / Ansgar Wille." Aachen : Shaker, 2004. http://d-nb.info/1172611998/34.

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