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Journal articles on the topic 'D-389'

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Published: 28 July 2024

Last updated: 31 July 2025

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1

Eckardt, J. R., R. Ramlau, R. Gervais, et al. "Compliance with oral topotecan in patients with non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)." Journal of Clinical Oncology 24, no. 18_suppl (2006): 7092. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.7092.

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7092 Background: Compliance with chemotherapy can affect treatment efficacy and patient safety. Selecting an oral chemotherapy regimen with good tolerability in appropriate patients is important. To determine general level of compliance of oral topotecan, a retrospective analysis was conducted on 3 international open-label, multicenter, 2-arm randomized, phase III studies of patients with NSCLC and SCLC. Methods: Patients were randomized to receive oral topotecan d1–5 q21d as follows: Study 387 (Ramlau et al, Proc ASCO, 2005) 2.3 mg/m2/d second-line vs IV docetaxel for NSCLC; Study 389 (Eckard

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Jong, Grant D. De. "Report ofGraphoderus occidentalisHorn (Coleoptera: Dytiscidae) from Mississippi, with Distributional Notes onGraphoderusDejean in the Contiguous United States." Coleopterists Bulletin 64, no. 4 (2010): 388–89. https://doi.org/10.1649/0010-065x-64.4.388.

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Jong, Grant D. De (2010): Report ofGraphoderus occidentalisHorn (Coleoptera: Dytiscidae) from Mississippi, with Distributional Notes onGraphoderusDejean in the Contiguous United States. The Coleopterists Bulletin 64 (4): 388-389, DOI: 10.1649/0010-065x-64.4.388, URL: http://dx.doi.org/10.1649/0010-065x-64.4.388

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Silva, Salvador Ordaz, Macotulio Soto Hernández, Imelda V. López Sánchez, Laura D. Carrazco Peña, Jorge L. Delgadillo Ángeles, and Julio C. Chacón Hernández. "First Record of Coniatus splendidulus (Fabricius) (Coleoptera: Curculionidae) in Baja California, Mexico, Collected from Tamarixhohenackeri Bunge (Tamaricaceae)." Coleopterists Bulletin 72, no. 2 (2018): 388–89. https://doi.org/10.1649/0010-065X-72.2.388.

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Silva, Salvador Ordaz, Hernández, Macotulio Soto, Sánchez, Imelda V. López, Peña, Laura D. Carrazco, Ángeles, Jorge L. Delgadillo, Hernández, Julio C. Chacón (2018): First Record of Coniatus splendidulus (Fabricius) (Coleoptera: Curculionidae) in Baja California, Mexico, Collected from Tamarixhohenackeri Bunge (Tamaricaceae). The Coleopterists Bulletin 72 (2): 388-389, DOI: 10.1649/0010-065X-72.2.388, URL: http://dx.doi.org/10.1649/0010-065x-72.2.388

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De, Brito Chirlei D., and Celso O. Azevedo. "Revision of the punctatus species-group of Dissomphalus Ashmead (Hymenoptera, Bethylidae)." Zootaxa 5536, no. 3 (2024): 389–431. https://doi.org/10.11646/zootaxa.5536.3.2.

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De Brito, Chirlei D., Azevedo, Celso O. (2024): Revision of the punctatus species-group of Dissomphalus Ashmead (Hymenoptera, Bethylidae). Zootaxa 5536 (3): 389-431, DOI: 10.11646/zootaxa.5536.3.2, URL: http://dx.doi.org/10.11646/zootaxa.5536.3.2

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Del-Claro, Kleber, and Helena Maura Torezan-Silingardi. "In search of unusual interactions. A commentary on: ‘Pollen adaptation to ant pollination: a case study from the Proteaceae’." Annals of Botany 126, no. 3 (2020): iv—v. http://dx.doi.org/10.1093/aob/mcaa126.

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This article comments on: Nicola Delnevo, Eddie J van Etten, Nicola Clemente, Luna Fogu, Evelina Pavarani, Margaret Byrne and William D Stock, Pollen adaptation to ant pollination: a case study from the Proteaceae, Annals of Botany, Volume 126, Issue 3, 1 September 2020, Pages 377–389, https://doi.org/10.1093/aob/mcaa058.

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Modarelli, Giuseppe Carlo, Roberta Paradiso, Carmen Arena, Stefania De Pascale, and Marie-Christine Van Labeke. "High Light Intensity from Blue-Red LEDs Enhance Photosynthetic Performance, Plant Growth, and Optical Properties of Red Lettuce in Controlled Environment." Horticulturae 8, no. 2 (2022): 114. http://dx.doi.org/10.3390/horticulturae8020114.

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Plant factories using artificial light to produce vegetables have high energy costs due to the high demand for electricity for lighting. Compared to conventional light sources, light-emitting diodes (LEDs) offer the possibility of tailoring the light spectrum and regulating light intensity and are more energy-efficient in terms of energy conversion regardless of the levels of lighting intensity. Optimal light intensity and daily light integral (DLI) requirements are key factors for plant growth; however, their values vary among species and varieties. Our experiment aimed to identify the best l

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Haavisto, Wonjeong, Julie Blaskewicz Boron, Sherry Willis, and Warner Schaie. "SOMATIC COMPLAINTS, A KEY FACTOR OF DEPRESSIVE SYMPTOMS ASSOCIATED WITH SUBJECTIVE MEMORY." Innovation in Aging 3, Supplement_1 (2019): S648. http://dx.doi.org/10.1093/geroni/igz038.2405.

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Abstract Prior research found depressive symptoms and subjective memory to be associated with objective memory (OM) performance. One key factor of subjective memory, as measured by the Memory Functioning Questionnaire (MFQ), is General Frequency of Forgetting (GFF). However, few studies focused on identifying specific factors of depressive symptoms when examining associations between depressive symptoms, subjective memory and OM. Using structural equation modeling, cross-sectional associations of factors in the CES-D (depressive symptoms) to the MFQ (subjective memory) and OM were investigated

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Baskal, Svetlana, Alexander Bollenbach, Bettina Henzi, Patricia Hafner, Dirk Fischer, and Dimitrios Tsikas. "Stable-Isotope Dilution GC–MS Measurement of Metformin in Human Serum and Urine after Derivatization with Pentafluoropropionic Anhydride and Its Application in Becker Muscular Dystrophy Patients Administered with Metformin, l-Citrulline, or Their Combination." Molecules 27, no. 12 (2022): 3850. http://dx.doi.org/10.3390/molecules27123850.

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Metformin (N,N-dimethylguanylguanidine) is one of the most prescribed drugs with pleiotropic, exerted in part by not fully elucidated mechanisms of action. We developed and validated a gas chromatography–mass spectrometry (GC–MS) method for the quantitative analysis of metformin (metformin-d0) in 10-µL aliquots of human serum and urine using N,N-[dimethylo-2H6]guanylguanidine (metformin-d6) as the internal standard. The method involves evaporation of the samples to dryness, derivatization with pentafluoropropionic (PFP) anhydride in ethyl acetate (30 min, 65 °C), and extraction into toluene. T

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Skouri, W., N. Boussetta, F. Ajili, S. Sayhi, L. Metoui, and B. Louzir. "Déficit en vitamine D dans la population tunisienne : à propos de 389 patients." Annales d'Endocrinologie 79, no. 4 (2018): 315–16. http://dx.doi.org/10.1016/j.ando.2018.06.363.

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10

CHIN, Cherng, Tien-Hsiung WENG, Lih-Hsing HSU, and Shang-Chia CHIOU. "The Spanning Connectivity of the Burnt Pancake Graphs." IEICE Transactions on Information and Systems E92-D, no. 3 (2009): 389–400. http://dx.doi.org/10.1587/transinf.e92.d.389.

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Thomas, Ziegler, N. Ziegler Tim, Peusquens Julia, et al. "Expanded morphological definition and molecular phylogenetic position of the Tam Dao mountain stream keelback Opisthotropis tamdaoensis (Squamata: Natricidae) from Vietnam." Revue suisse de Zoologie 124, no. 2 (2017): 377–89. https://doi.org/10.5281/zenodo.893551.

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Thomas Ziegler, Tim N. Ziegler, Julia Peusquens, Patrick David, Thanh N. Vu, Cuong T. Pham, Truong Q. Nguyen, Minh D. Le (2017): Expanded morphological definition and molecular phylogenetic position of the Tam Dao mountain stream keelback Opisthotropis tamdaoensis (Squamata: Natricidae) from Vietnam. Revue suisse de Zoologie 124 (2): 377-389, DOI: 10.5281/zenodo.893551

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Van Laarhoven, Jan. "Titles and Subtitles of the Policraticus A Proposal." Vivarium 32, no. 2 (1994): 131–60. http://dx.doi.org/10.1163/156853494x00087.

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AbstractIntroduction and Prologue 489 lines Part I. Officials and their ado. total: 6.214 lines Bk. 1. Curial occupations: 1.309 lines a) starting-point 3 ch.: 70 l. b) games 5 ch.: 820 l. c) varieties of magic 5 ch.: 419 l. Bk. 2. The truth of signs: prol.: 14 1. 3.116 lines a) true and false signs 3 ch.: 142 1. b) exc.: Jerusalem A.D. 70 6 ch.: 385 1. c) sequel: signs 5 ch.: 127 l. d) dreams 3 ch.: 386 l. e) a problem 9 ch.: 1.272 l. f) prognostications 3 ch.: 790 l. Bk. 3. The falsehood of flattery: prol.: 26 l. 1.789 lines a) introduction 3 ch.: 194 1. b) flattery 4 ch.: 373 1. c) the thea

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Sangro, Bruno, Peter R. Galle, Robin Kate Kelley, et al. "Patient-reported outcomes from the phase 3 HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): 4074. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.4074.

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4074 Background: In the Phase 3 HIMALAYA study (NCT03298451) of patients (pts) receiving first-line treatment for unresectable hepatocellular carcinoma (uHCC), a single priming dose of tremelimumab (T; anti-CTLA-4) plus durvalumab (D; anti-PD-L1) in the STRIDE regimen significantly improved overall survival (OS) vs sorafenib (S), and D monotherapy was noninferior to S for OS (Abou-Alfa et al. J Clin Oncol 2022;40[suppl 4]. Abs 379). Methods: A pre-planned secondary objective of HIMALAYA was to assess pt-reported outcomes (PROs) in pts receiving STRIDE (T 300 mg plus D 1500 mg [one dose] plus D

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Sangro, Bruno, Peter R. Galle, Robin Kate Kelley, et al. "Patient-reported outcomes from the phase 3 HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): 4074. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.4074.

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4074 Background: In the Phase 3 HIMALAYA study (NCT03298451) of patients (pts) receiving first-line treatment for unresectable hepatocellular carcinoma (uHCC), a single priming dose of tremelimumab (T; anti-CTLA-4) plus durvalumab (D; anti-PD-L1) in the STRIDE regimen significantly improved overall survival (OS) vs sorafenib (S), and D monotherapy was noninferior to S for OS (Abou-Alfa et al. J Clin Oncol 2022;40[suppl 4]. Abs 379). Methods: A pre-planned secondary objective of HIMALAYA was to assess pt-reported outcomes (PROs) in pts receiving STRIDE (T 300 mg plus D 1500 mg [one dose] plus D

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Abou-Alfa, Ghassan K., Stephen Lam Chan, Masatoshi Kudo, et al. "Phase 3 randomized, open-label, multicenter study of tremelimumab (T) and durvalumab (D) as first-line therapy in patients (pts) with unresectable hepatocellular carcinoma (uHCC): HIMALAYA." Journal of Clinical Oncology 40, no. 4_suppl (2022): 379. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.379.

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379 Background: A single priming dose of T (anti-CTLA-4) added to D (anti-PD-L1) in the STRIDE (Single T Regular Interval D) regimen, formerly T300+D, showed encouraging clinical activity and limited toxicity in a phase 2 uHCC study (Study 22, NCT02519348), suggesting single exposure to T is sufficient to improve upon D activity. HIMALAYA (NCT03298451) evaluated the efficacy and safety of STRIDE or D vs sorafenib (S) in uHCC. Methods: HIMALAYA is an open-label, multicenter, phase 3 study, in which pts with uHCC and no prior systemic therapy were initially randomized to STRIDE (T 300 mg plus D

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16

Zhuo, Yafen, Lin Ling, Zhichun Sun, et al. "Vitamin D and iodine status was associated with the risk and complication of type 2 diabetes mellitus in China." Open Life Sciences 16, no. 1 (2021): 150–59. http://dx.doi.org/10.1515/biol-2021-0019.

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Abstract The purpose of this study was to assess the relationship between 25-hydroxyvitamin D (25(OH)D), urinary iodine concentration (UIC), and type 2 diabetes mellitus (T2DM) risk and complications and to establish a model to predict T2DM in the general population. A total of 567 adults (389 T2DM patients and 178 controls) were enrolled, and the levels of 25(OH)D, iodine, and blood biochemical parameters were measured. Pearson’s correlation analysis showed an inverse correlation between 25(OH)D level, UIC, and T2DM risk. Low 25(OH)D level was a risk factor for developing T2DM (OR, 0.81; 95%

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17

Wadzinski, B. E., M. F. Shanahan, K. B. Seamon, and A. E. Ruoho. "Localization of the forskolin photolabelling site within the monosaccharide transporter of human erythrocytes." Biochemical Journal 272, no. 1 (1990): 151–58. http://dx.doi.org/10.1042/bj2720151.

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Chemical and proteolytic digestion of intact erythrocyte glucose transporter as well as purified transporter protein has been used to localize the derivatization site for the photoaffinity agent 3-[125I]iodo-4-azido-phenethylamino-7-O-succinyldeacetylforskol in [(125I]IAPS-forskolin). Comparison of the partial amino acid sequence of the labelled 18 kDa tryptic fragment with the known amino acid sequence for the HepG2 glucose transporter confirmed that the binding site for IAPS-forskolin is between the amino acid residues Glu254 and Tyr456. Digestion of intact glucose transporter with Pronase s

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Costenbader, K. H., D. Feskanich, M. Holmes, E. W. Karlson, and E. Benito-Garcia. "Vitamin D intake and risks of systemic lupus erythematosus and rheumatoid arthritis in women." Annals of the Rheumatic Diseases 67, no. 4 (2007): 530–35. http://dx.doi.org/10.1136/ard.2007.072736.

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Objectives:Vitamin D has immune-modulating effects and may protect against the development of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).Methods:We identified incident cases of SLE and RA among 186 389 women followed from 1980 to 2002 in the Nurses’ Health Study and Nurses’ Health Study II cohorts. We excluded subjects where SLE or RA was not confirmed by medical record review, and those who failed to return questionnaires. Semi-quantitative food frequency questionnaires assessed vitamin D intake from food and supplements. We used cumulative-updated total energy-adjusted

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Hassan, Mohammad Maksudul, Naimul Hasan, Iqbal Shahriar Khan, Md Ekramul Hasan, Mohammad Tohidul Amin, and Toshinobu Tokumoto. "Effects of plant growth regulators on eelgrass (Zostera Marina L.) Germination." Bangladesh Journal of Botany 54, no. 2 (2025): 389–92. https://doi.org/10.3329/bjb.v54i2.82325.

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Eelgrass (Zostera marina L.) plays a vital role in coastal ecosystems, but its restoration is often hindered by low seed germination rates. This study was aimed to evaluate the effects of plant growth regulators (PGRs) on enhancing eelgrass seed germination under controlled conditions. Seeds were treated with different concentrations of GA3, 2,4-D and NAA. Results demonstrated that PGRs application significantly increased germination rates compared to control. These findings indicated that PGRs could be an effective tool for increasing the success of eelgrass restoration initiatives. Banglades

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Polkovnikov, Anatoli, Subir Sachdev, and Matthias Vojta. "Erratum to: “Spin collective mode and quasiparticle contributions to STM spectra of d-wave superconductors with pinning” [Physica C 388–389 (2003) 19–24]." Physica C: Superconductivity 391, no. 4 (2003): 381. http://dx.doi.org/10.1016/s0921-4534(03)01210-3.

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Kalin, R., T. Turan, M. Ozan Atasoy, and H. Isidan. "Characterization of fowl aviadenovirus species in backyard flocks in Turkey." Journal of the Hellenic Veterinary Medical Society 73, no. 3 (2022): 4667–74. http://dx.doi.org/10.12681/jhvms.28046.

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Fowl aviadenovirus infections show a worldwide distribution in poultry at all ages and the incidence of the disease is increasing year after year. Most of the studies have been exhibited the situation of the disease in commercial chickens especially in broilers but there is not sufficient data to estimate in backyards. Totally 389 internal organ samples were collected from 56 flocks from suspicious backyard chickens at ages between 10-35 weeks. Samples were tested by PCR method and nucleotide sequences of hexon genes were used for phylogenetic analyses and comparing with other FAdV sequences s

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Kelley, George A., and Kristi S. Kelley. "Effects of Diet, Aerobic Exercise, or Both on Non-HDL-C in Adults: A Meta-Analysis of Randomized Controlled Trials." Cholesterol 2012 (November 8, 2012): 1–5. http://dx.doi.org/10.1155/2012/840935.

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Purpose. To use the meta-analytic approach to examine the effects of diet (D), aerobic exercise (E), or both (DE) on non-high-density lipoprotein cholesterol (non-HDL-C) in adults. Methods. Randomized controlled trials in adults ≥18 years of age were included. A mixed-effect model was used to combine effect size (ES) results within each subgroup and to compare subgroups (Qb). Heterogeneity was examined using the Q and I2 statistics, and 95% confidence intervals (CI) were also calculated. Statistical significance was set at P≤0.05, while a trend for statistical significance was set between P&gt

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Vanderlinde, Thyago, Eduardo Guimarães Dupim, Nestor O. Nazario-Yepiz, and Antonio Bernardo Carvalho. "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in the mojavensis Cluster." Journal of Heredity 110, no. 1 (2018): 118–23. http://dx.doi.org/10.1093/jhered/esy059.

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Abstract Three North American cactophilic Drosophila species, D. mojavensis, D. arizonae, and D. navojoa, are of considerable evolutionary interest owing to the shift from breeding in Opuntia cacti to columnar species. The 3 species form the “mojavensis cluster” of Drosophila. The genome of D. mojavensis was sequenced in 2007 and the genomes of D. navojoa and D. arizonae were sequenced together in 2016 using the same technology (Illumina) and assembly software (AllPaths-LG). Yet, unfortunately, the D. navojoa genome was considerably more fragmented and incomplete than its sister species, rende

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Ownby, Raymond L. "Rourke, B. P., Bakker, D. J., Fisk, J. L., & Strang, J. D. (1983). Child neuropsychology. New York: Guilford Press, 389 pp., $29.50." Psychology in the Schools 23, no. 2 (1986): 219–22. http://dx.doi.org/10.1002/1520-6807(198604)23:2<219::aid-pits2310230218>3.0.co;2-o.

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Ravishankar, K. "Re: “Daily Migraine With Aura: A New Migraine Variant” (Merims D, Kuritzky A. Headache . 2000;40:389‐392)." Headache: The Journal of Head and Face Pain 41, no. 1 (2001): 102. http://dx.doi.org/10.1046/j.1526-4610.2001.111006102.x.

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Akhavein, F., E. Jean St.-Michel, E. Seifert, and C. V. Rohlicek. "Decreased left ventricular function, myocarditis, and coronary arteriolar medial thickening following monocrotaline administration in adult rats." Journal of Applied Physiology 103, no. 1 (2007): 287–95. http://dx.doi.org/10.1152/japplphysiol.01509.2005.

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Decreased right as well as left ventricular function can be associated with pulmonary hypertension (PH). Numerous investigations have examined cardiac function following induction of pulmonary hypertension with monocrotaline (MCT) assuming that MCT has no direct cardiac effect. We tested this assumption by examining left ventricular function and histology of isolated and perfused hearts from MCT-treated rats. Experiments were performed on 50 male Sprague-Dawley rats [348 ± 6 g (SD)]. Thirty-seven rats received MCT (50 mg/kg sc; MCT group) while the remainder did not (Control group). Three week

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Rousselot, Philippe, Hyacinthe Johnson-Ansah, Françoise Huguet, et al. "Personalized Daily Doses of Imatinib By Therapeutic Drug Monitoring Increase the Rates of Molecular Responses in Patients with Chronic Myeloid Leukemia. Final Results of the Randomized OPTIM Imatinib Study." Blood 126, no. 23 (2015): 133. http://dx.doi.org/10.1182/blood.v126.23.133.133.

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Abstract Background Imatinib mesylate (IM) at 400 mg/d remains a standard for first line therapy in patients (pts) with newly diagnosed chronic phase CML (CP-CML). A sub analysis of the IRIS study (Larson et al. Blood, 2008) demonstrated that pts with high IM trough levels achieved higher rates of major molecular response (MMR). The level of 1000 ng/ml was established as the [C]min value threshold to predict molecular response (Picard et al. Blood, 2007). We conducted a randomized trial to evaluate the value of IM dose optimization based on the monitoring of [C]min levels in newly diagnosed CP

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Wu, Xianfu, Xiaoming Gong, Heather D. Foley, Matthias J. Schnell, and Zhen F. Fu. "Both Viral Transcription and Replication Are Reduced when the Rabies Virus Nucleoprotein Is Not Phosphorylated." Journal of Virology 76, no. 9 (2002): 4153–61. http://dx.doi.org/10.1128/jvi.76.9.4153-4161.2002.

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ABSTRACT Rabies virus nucleoprotein (N) plays vital roles in regulation of viral RNA transcription and replication by encapsidation of the nascent genomic RNA. Rabies virus N is phosphorylated, and previous studies demonstrated that mutation of the phosphorylated serine at position 389 to alanine resulted in reduction of viral transcription and/or replication of a rabies virus minigenome. In the present study, we mutated the serine (S) at position 389 to alanine (A), glycine (G), aspartic acid (D), asparagine (N), glutamic acid (E), and glutamine (Q) and examined the effects of these mutations

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Gilbert, Richard D. "Carbon disulphide in organic chemistry, by A. D. Dunn and W.-D. Rudorf, John Wiley & Sons, New York, 1989, 389 pp. Price: $89.95." Journal of Polymer Science Part C: Polymer Letters 28, no. 13 (1990): 447. http://dx.doi.org/10.1002/pol.1990.140281308.

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van Ballegooijen, Adriana, Joline Beulens, Leon Schurgers, et al. "Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults." Nutrients 11, no. 2 (2019): 231. http://dx.doi.org/10.3390/nu11020231.

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Vitamin D supplementation has been widely promoted to restore 25-hydroxyvitamin D concentrations; however, experimental evidence suggests a nutrient interaction with vitamin K. We assessed the effects of 1200 IU vitamin D3 per day versus placebo for six months on vitamin K status in a randomized, double-blind, placebo-controlled trial with participants aged 60–80 years with depressive symptoms and ≥1 functional limitation for a secondary analysis. Stored baseline and six-month follow-up blood samples were available for 131 participants (n = 65 placebo vs. n = 66 vitamin D supplementation). We

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Kwadha, Charles A., Louis A. Okwaro, Isabella Kleman, et al. "Detection of the spotted wing drosophila, Drosophila suzukii, in continental sub-Saharan Africa." Journal of Pest Science 94, no. 2 (2021): 251–59. http://dx.doi.org/10.1007/s10340-021-01330-1.

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AbstractThe spotted wing drosophila, Drosophila suzukii Matsumura, is an insect pest of soft-skinned fruit, native to Eastern Asia. Since 2008, a world-wide dispersal of D. suzukii is seen, characterized by the establishment of the pest in many Asian, American and European countries. While the potential for invasion of continental Africa by D. suzukii has been predicted, its presence has only been shown for Morocco in Northern Africa. Knowledge about a possible establishment in other parts of the continent is needed as a basis for pest management. In 2019, we carried out a first survey in thre

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Thölking, Gerold, Sophia Hüls, Katharina Schütte-Nütgen, et al. "Optimization of the Tacrolimus Concentration-to-Dose Ratio Cut-Off Value to Define Metabolism Groups." Journal of Clinical Medicine 14, no. 8 (2025): 2542. https://doi.org/10.3390/jcm14082542.

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Background/Objectives: The tacrolimus (Tac) concentration-to-dose ratio (C/D ratio) has been described as a predictive marker for several outcome parameters after renal transplantation (RTx). Different C/D ratio values are used to define fast (low C/D ratio) and slow Tac metabolizers (high C/D ratio). In this study, the R package was used to determine the optimal C/D ratio cut-off value to define the Tac metabolism type with a high predictive value for the development of renal function. Methods: The data of 389 RTx patients who received an initial immunosuppression with immediate-release tacro

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Tao, Y. P., T. P. Misko, A. C. Howlett, and C. Klein. "Nitric oxide, an endogenous regulator of Dictyostelium discoideum differentiation." Development 124, no. 18 (1997): 3587–95. http://dx.doi.org/10.1242/dev.124.18.3587.

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We have previously demonstrated that nitric oxide (NO)-generating compounds inhibit D. discoideum differentiation by preventing the initiation of cAMP pulses (Tao, Y., Howlett, A. and Klein, C. (1996) Cell. Signal. 8, 37–43). In the present study, we demonstrate that cells produce NO at a relatively constant rate during the initial phase of their developmental cycle. The addition of oxyhemoglobin, an NO scavenger, stimulates cell aggregation, suggesting that NO has a negative effect on the development of aggregation competence. Starvation of cells in the presence of glucose, which has been sho

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Venkatachalam, Sampath Kumar, and SARAVANAM KARTHIKEYAN. "Notes on nomenclature and distribution of some taxa of Piper L. (Piperaceae)." Phytotaxa 167, no. 2 (2014): 209. http://dx.doi.org/10.11646/phytotaxa.167.2.9.

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The species Piper petiolatum de Candolle (1866: 161) was first described based on specimens collected by J. D. Hooker and T. Thomson from Khasia hills and by W. Griffith (Kew Distribution numbers 4405 & 4410, these numbers were assigned in 1860’s at Kew before distributing the specimens to different herbaria) from East Bengal (present day Bangladesh – however, the labels on the sheets reveal that the Griffith specimens were actually collected from NE India, which is discussed below). Three years later, in A.P. de Candolle’s Prodromus, A.C.P. de Candolle cited these specimens under Chavica

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Steytler, John, der Ryst Elna van, Charles Craig, et al. "Clinical Presentation, Treatment Response, and Virology Outcomes of Women Who Seroconverted in the Dapivirine Vaginal Ring Trials—The Ring Study and DREAM." Clinical Infectious Diseases 76, no. 3 (2023): 389–97. https://doi.org/10.5281/zenodo.7936873.

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This is the accepted manuscript version of the work published in its final form as Steytler, J., Ryst, E. V. D., Craig, C., Baelen, B. V., Nuttall, J., Niekerk, N. V., Mellors, J., Parikh, U., Wallis, C., & . (2023). Clinical presentation, treatment response, and virology outcomes of women who seroconverted in the dapivirine vaginal ring trialsthe ring study and dream. <em>Clinical Infectious Diseases</em>, <em>76</em>(3), 389-397. https://doi.org/10.1093/cid/ciac804 Deposited by shareyourpaper.org and openaccessbutton.org. We've taken reasonable steps to ensur

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Montani, Eugenia, Candelaria Cordini, Marcelo Romano, Germán Saigo, Marcelo Janik, and Ignacio Barberis. "Nidificación de Callonetta leucophrys y Dendrocygna autumnalis en cajas nido en Corrientes, Argentina." El Hornero 34, no. 1 (2023): 7–16. http://dx.doi.org/10.56178/eh.v34i1.468.

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En Argentina, el Pato de Collar (Callonetta leucophrys) y el Sirirí Vientre Negro (Dendrocygna autumnalis) son especies abundantes, pero poco estudiadas. Para describir la distribución estacional de las nidificaciones, el número de huevos/postura y los huevos de estas especies, se trabajó durante seis temporadas reproductivas con cajas nido dispuestas en numerosos humedales del sudoeste de la provincia de Corrientes. Se registraron 389 nidificaciones de C. leucophrys y 979 nidificaciones de D. autumnalis. El pico de nidificación de C. leucophrys ocurrió en octubre-noviembre y el de D. autumnal

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Boltz, Marie, Jacqueline Mogle, and Ashley Kuzmik. "PATIENT AND FAMILY PARTNER OUTCOMES OF THE FAM-FFC TRIAL." Innovation in Aging 7, Supplement_1 (2023): 93. http://dx.doi.org/10.1093/geroni/igad104.0301.

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Abstract The Fam-FFC trial tested the hypotheses that patients who participated in Fam-FFC would have more return to baseline function, more physical activity, and less delirium, depressive symptoms, and behavioral symptoms of distress, and that care partners would demonstrate increased preparedness for caregiving (primary outcome) and less anxiety, strain, and burden, as compared to participants in the control arm. The likelihood of returning to baseline function across time for Fam-FFC participants was twice that of the control group by the end of 6 months (OR = 2.39, p =.011). Fam-FFC was a

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Neal, G. E. "D. H. Hutson, J. Caldwell and G. D. Paulson (eds) Intermediary Xenobiotic Medicine in Animals. Methodology, Mechanisms and Significance Taylor & Francis, London, 1989; 389 pp." Journal of Applied Toxicology 11, no. 1 (1991): 77. http://dx.doi.org/10.1002/jat.2550110114.

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Caddick, Mark X., and Herbert N. Arst. "Deletion of the 389 N-Terminal Residues of the Transcriptional Activator AREA Does Not Result in Nitrogen Metabolite Derepression in Aspergillus nidulans." Journal of Bacteriology 180, no. 21 (1998): 5762–64. http://dx.doi.org/10.1128/jb.180.21.5762-5764.1998.

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ABSTRACT Utilizing a homologous gene replacement in order to retain the native promoter and 5′ and 3′ untranslated messenger regions (and thereby ensure physiological validity), we have shown that deletion of the N-terminal 389 amino acids of the transcriptional activator AREA does not result in nitrogen metabolite derepression inAspergillus nidulans. Our results provide no evidence for a modulating interaction involving the N terminus of AREA and contrast with those of H. K. Lamb, A. L. Dodds, D. R. Swatman, E. Cairns, and A. R. Hawkins (J. Bacteriol. 179:6649–6656, 1997), who used nontargete

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Mehmet, Yıldırım, Fırat Fatih, and Yıldırım Cüneyt. "Lise Öğrencilerinin Psikolojik İyi Oluş Düzeyleri ve Olumlu Düşünme Becerileri Arasındaki İlişkinin İncelenmesi." International JOURNAL OF SOCIAL, HUMANITIES AND ADMINISTRATIVE SCIENCES 10, no. 2 (2024): 307–17. https://doi.org/10.5281/zenodo.10898005.

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Bu çalışmada, lise öğrencilerinin psikolojik iyi oluş düzeyleri ile olumlu düşünme beceri düzeyleri arasındaki ilişkinin incelenmesini amaçlanmaktadır. Araştırmaya Yozgat merkezde öğrenim gören lise düzeyinde 389 öğrenci gönüllü katılmıştır. Çalışmada iki farklı veri toplama aracı kullanılmıştır. Çalışmaya katılanların psikolojik iyi oluş düzeylerinin tespiti için Psikolojik İyi Oluş Ölçeği (PİOÖ) kullanılırken, olumlu düşünme becerilerinin belirlenmesi amacıyla Olumlu

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Garbacz, Piotr, David Håkansson, and Henrik Rosenkvist. "John D. Sundquist. Morphosyntactic Change in the History of the Mainland Scandinavian Languages. Ann Arbor, MI: ProQuest, 2002, 389 pp." Nordic Journal of Linguistics 30, no. 1 (2007): 137–46. http://dx.doi.org/10.1017/s0332586507001680.

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Sulaiman, Rizgar Rahim, Hardi Fattah Marif, Basim Abdulwahid Ali, Kwestan Najm Ali, and Muhamad Omer Baba Shekh. "Genetic Variability and Antibacterial Sensitivity of Dichelobacter nodosus and Fusobacterium necrophorum Infection in Sheep Sulaimani Province, Kurdistan Region, Iraq." Iraqi Journal of Veterinary Medicine 48, no. 1 (2024): 93–100. http://dx.doi.org/10.30539/xxn4db22.

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Footrot is a significant health problem in ruminants, especially sheep, caused by the bacteria Dichelobacter nodosus and Fusobacterium necrophorum. Infected animals may become lame and lose body condition. The aim of this study was to investigate whether sheep had mixed infections with D. nodosus and F. necrophorum, the global genetic relationships of both target genes (lktA and 16S rRNA genes) with different reference genes, and the degree of genetic heterogeneity between the standard serogroups of D. nodosus were studied. In addition, to detect the antibacterial sensitivity against these two

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Singh, Khushwant, and Jiban Kumar Kundu. "Variations in coat protein sequence of Wheat streak mosaic virus among crop and non-crop hosts." Crop and Pasture Science 68, no. 4 (2017): 328. http://dx.doi.org/10.1071/cp17025.

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Wheat streak mosaic virus (WSMV) has become a re-emerging pathogen in recent years in the Czech Republic. Crop (e.g. wheat, barley, maize) and non-crop grasses from the Poaceae family are the natural hosts of the virus. Here, we report the results from coat protein (CP) gene-sequence analysis of WSMV isolates from wheat crops (four cultivars: Turondot, Bodyček, Avenue, Hymack) and three grass species (Agropyron repens, Phleum pratense, Poa pratensis). Phylogenetic reconstruction of putative CP sequences showed that all tested isolates clustered with existing type B isolates of WSMV (originatin

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Ennabili, Abdeslam, and Mohammed Ater. "Flore (Pteridophyta et Spermatophyta) des zones humides du Maroc Méditérranéen: Inventaire et écologie." Acta Botanica Malacitana 21 (December 1, 1996): 221–39. http://dx.doi.org/10.24310/abm.v21i0.8677.

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Malgré l'intéret qu' on porte de plus en plus aux zones humides á travers le monde, peu d' etudes ont été consacrées á la flore hygrophile marocaine. Aprés avoir prospecté 45 stations, on a évalué la diversité spécifique des hygrophytes du Maroc méditerranéen á partir de 70 relevés floristiques. Sur les 389 espéces reconnues dans cette etude, 175 especes sont caractéristiques des zones humides. Les espéces rares ou nouvellement citées ont été soulignées. D'autre part, les phytocenoses observées ant été classées en fonction de la physionomie et de la composition spécifique. Une attention partic

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Juraschek, Stephen P., Xiaoming Zhang, Vinoth Ranganathan, and Vernon W. Lin. "United States Registered Nurse Workforce Report Card and Shortage Forecast." American Journal of Medical Quality 27, no. 3 (2011): 241–49. http://dx.doi.org/10.1177/1062860611416634.

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Registered nurses (RNs) play a critical role in health care delivery. With an aging US population, health care demand is growing at an unprecedented pace. Using projected changes in population size and age, the authors developed demand and supply models to forecast the RN job shortage in each of the 50 states. Letter grades were assigned based on projected RN job shortage ratios. The number of states receiving a grade of “D” or “F” for their RN shortage ratio will increase from 5 in 2009 to 30 by 2030, for a total national deficit of 918 232 (725 619 - 1 112 112) RN jobs. There will be signifi

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Juraschek, Stephen P., Xiaoming Zhang, Vinoth Ranganathan, and Vernon W. Lin. "Republished: United States Registered Nurse Workforce Report Card and Shortage Forecast." American Journal of Medical Quality 34, no. 5 (2019): 473–81. http://dx.doi.org/10.1177/1062860619873217.

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Registered nurses (RNs) play a critical role in health care delivery. With an aging US population, health care demand is growing at an unprecedented pace. Using projected changes in population size and age, the authors developed demand and supply models to forecast the RN job shortage in each of the 50 states. Letter grades were assigned based on projected RN job shortage ratios. The number of states receiving a grade of “D” or “F” for their RN shortage ratio will increase from 5 in 2009 to 30 by 2030, for a total national deficit of 918 232 (725 619 - 1 112 112) RN jobs. There will be signifi

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Holland, R. F. "Rush Rhees on Religion and Philosophy D. Z. Phillips (ed.) Cambridge University Press, 1997, pp. xii + 389, £50 (US $69.95) Hb." Philosophy 73, no. 3 (1998): 495–523. http://dx.doi.org/10.1017/s0031819198230105.

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Carvalho, Victor V., Alexandre Perdigão, Tiago S. Acedo, Guilherme S. Vasconcellos, and Luis Fernando Tamassia. "391 Effects of increasing carbohydrases levels on productive performance of beef cattle fed feedlot finishing diets." Journal of Animal Science 97, Supplement_3 (2019): 155. http://dx.doi.org/10.1093/jas/skz258.318.

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Abstract Our objective was to evaluate the effects of feeding increasing exogenous carbohydrases levels on cattleˈ performance, when fed a 90-d feedlot finishing diet. A total of 240 Nellore bulls (IBW = 389 ± 27 kg) were distributed in 24 pens (10 animals/pen), in a randomized complete block design (6 pens/treatment). The basal diet was composed by 15% sugarcane bagasse, 72.8% ground corn, 7.6% soybean meal and 4.6 % mineral-vitamin premix (DM basis). The treatments were: 1) control: No addition of carbohydrases blend; 2) Blend1, in g/animal/d: 1 g of Ronozyme® WX (xylanase) + 3.75 g of Ronzy

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Slayton, Mark D., Zackariah A. Farah, Jin Heon Jeon, et al. "Abstract 431: Malic enzyme 2 inhibition reveals metabolic vulnerability in serine-dependent triple-negative breast cancer." Cancer Research 84, no. 6_Supplement (2024): 431. http://dx.doi.org/10.1158/1538-7445.am2024-431.

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Abstract Background & Hypothesis: Treatments for triple-negative breast cancer (TNBC) are limited to chemotherapy, PARP inhibitors and immunotherapies. Tumor metabolism seeks to identify metabolic pathways preferentially utilized by cancer. Malic enzyme 2 (ME2) has a role in the malate-aspartate shuttle and pyruvate and NADPH production, contributing to the redox balance and metabolite synthesis. We demonstrated that ME2 knockdown inhibits growth of TNBC cells with upregulated serine biosynthesis pathway. We hypothesized that ME2 knock-down (kd) would be growth inhibitory in vivo. Methods:

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Yang, Sophie Xin, Siyu Cheng, Yuanfeng Sun, Xiangdong Tang, and Zhijiao Huang. "Circadian Disruption in Civilian Airline Pilots." Aerospace Medicine and Human Performance 95, no. 7 (2024): 381–89. http://dx.doi.org/10.3357/amhp.6316.2024.

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INTRODUCTION: Most airline pilots reported having suffered from sleep disorders and fatigue due to circadian disruption, a potential risk to flight safety. This study attempted to uncover the actual scenario of circadian disruption and working load status among airline pilots.METHODS: In study 1, 21 pilots were invited to participate in a 14-d sleep monitoring and a dual 2-back test to monitor their sleep patterns and cognitive function level. To provide an in-depth view, data from scheduled flights, including 567 airline pilots, was analyzed in Study 2. The present study used cluster analysis

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