Dissertations / Theses on the topic 'D-341'
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Huber, Barbara [Verfasser], and Heinrich [Akademischer Betreuer] Bahlburg. "Provenance analysis of sediments from IODP Expedition 341 sites U1417 and U1418 : implications on climate-tectonic interactions at the southern Alaska continental margin / Barbara Huber ; Betreuer: Heinrich Bahlburg." Münster : Universitäts- und Landesbibliothek Münster, 2019. http://d-nb.info/1188706454/34.
Full textNasr, Al-Ghadban Rihab Raif. "Ciblage thérapeutique de Tax et de la voie NF-kB dans la leucémie T de l' adulte liée au rétrovirus HTLV-I." Paris 7, 2005. http://www.theses.fr/2005PA077074.
Full textOliveira, Tamiris Garbiatti de. "Estudo in vitro da interação entre herbicidas e espermatozoide humano utilizando a Espectroscopia de Espalhamento Raman." Universidade do Oeste Paulista, 2015. http://bdtd.unoeste.br:8080/tede/handle/tede/341.
Full textThe unlimited use of pesticides, besides contribute with to increase environmental pollution, is also influencing negatively the health of the living beings, including the people health. Many studies show the result these chemicals in the reproductive system of animals and even same at man, can cause infertility problem, which can originate, among other factors, the low sperm quality and quantity. This is study aimed at evaluating human sperm quality parameters and the chemical evaluation of the core of the sperm trough Raman Scaterring Spectroscopy, after in vitro exposure to different concentrations of 2,4-dichlorophenoxyacetic acid (2,4-D) and atrazine. The choice of the use of the these herbicides was because they are widely use throughout the world, especially in Brazil, highlighted the west Paulista region, used at cane sugar plantation, significant culture of the region. In this context, sperm samples were selected according to the normal testing parameters that evaluate sperm quality, such as liquefaction, viscosity, appearance, volume, pH, sperm, vitality, morphology and motility. Semen samples of 10 healthy donor were exposed to study herbicides varying the concentration and time. After the different exposures (0.05, 0.5, 1.0, 5.0 and 125 μg/mL, 30 and 60 min), the analysis of motility and vitality were again evaluated. The Raman Scaterring spectra were obtained from samples control sperm and after exposure to the herbicide 2,4-D e atrazine at concentration of 125 μg/mL and 60 min incubation. The progressive motility and total motility decreased from the concentration 0,5 μg/mL at times 30 and 60 minutes while the percentage of sperm properties increased. The progressive motility and total motility decreased from the concentration 0.5 mg / mL at times 30 and 60 minutes while the percentage of sperm immotile increased. The vitality (viable sperm) decreased significantly (p <0.05) from the exposure concentration 0.5 μg/mL to 2,4-D and from 1.0 μg/mL atrazine, at times 30 and 60 minutes, showing that there is a functional change of trend of human sperm after exposure to these herbicides, and this change is intensified with the exposure time factor and concentration of herbicides. Through the Raman Scaterring technique allowed us to characterize normal human sperm and exposed to herbicides and verify the change in the molecular structure in the exposed sperm, evidenced by changes in relative intensities of the bands 785, 1095, 1255, 1336, 1374, 1486 and 1575 cm-1 treated with 2,4-D and a decrease at 1095 after exposure to atrazine. These results indicate the modification of nitrogenous bases and the phosphate group that make up DNA present in the nucleus of the sperm.
A utilização desenfreada de praguicidas, além de contribuir com o agravamento da poluição ambiental, também está influenciando de forma negativa a saúde dos seres vivos, inclusive a saúde das pessoas. Muitos estudos mostram a interferência desses produtos químicos no sistema reprodutor de animais e até mesmo do homem, podendo acarretar problemas de infertilidade, que podem ser originados, dentre vários fatores, pela baixa quantidade e qualidade espermática. Este estudo visa á avaliação de parâmetros de qualidade espermática humana e a avaliação química do núcleo do espermatozoide, por meio de Espectroscopia de Espalhamento Raman, após a exposição in vitro a diferentes concentrações de ácido 2,4-diclorofenoxiacético (2,4-D) e atrazina. Estes herbicidas são amplamente utilizados em todo o mundo, principalmente no Brasil, em destaque a região do Oeste Paulista, por serem empregados na cana-de-açúcar, cultura significativa da região. Neste contexto, foram selecionadas amostras de espermatozoides de acordo com os parâmetros normais de testes que avaliam a qualidade espermática, como: liquefação, viscosidade, aparência, volume, pH, concentração de espermatozoides, vitalidade, morfologia e motilidade. Amostras de sêmen de 10 doadores saudáveis foram expostas aos herbicidas de estudo, variando o tempo e a concentração. Após as diferentes exposições (0,05; 0,5; 1,0; 5,0 e 125 μg/mL, 30 e 60 min), as análises de motilidade e vitalidade foram novamente avaliadas. Os espectros de Espalhamento Raman foram obtidos das amostras de espermatozoide controle e após a exposição aos herbicidas 2,4-D e atrazina na concentração de 125 µg/mL em 60 min de incubação. A motilidade progressiva e motilidade total diminuíram a partir da concentração 0,5 μg/mL nos tempos 30 e 60 min enquanto que a porcentagem de espermatozoides imóveis aumentou. A vitalidade (espermatozoides viáveis) diminuiu significativamente (p<0,05) a partir da exposição da concentração 0,5 μg/mL para o 2,4-D e a partir de 1,0 μg/mL para a atrazina, nos tempos 30 e 60min, mostrando-se que há uma tendência de alteração funcional do espermatozoide humano após a exposição a estes herbicidas, e esta alteração é intensificada com o fator de tempo de exposição e concentração dos herbicidas testados. Por meio da técnica de Espalhamento Raman foi possível caracterizar o espermatozoide humano normal e os expostos aos herbicidas e verificar a alteração na estrutura molecular nos espermatozoides expostos, evidenciadas pelas alterações nas intensidades relativas das bandas 785, 1095, 1255, 1336, 1374, 1486 e 1575 cm-1 do tratado com 2,4-D, e uma diminuição na banda de 1095 após a exposição à atrazina. Estes resultados indicam a alteração das bases nitrogenadas e do grupo fosfato que compõem o DNA presente no núcleo do espermatozoide.
Jaffar, Zainudin. "The concept and application of ḍamān in Islamic commercial law." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/17552.
Full textKang, W. "Functional studies of SP-D in innate immunity, and its binding protein gp-340 in gastric epithelial development." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249276.
Full textFRANCISCO, XAVIER. "Interet du haubanage-plaque dans les fractures malleolaires selon la methode du docteur d. Noyer : a propos de 34 observations." Lyon 1, 1991. http://www.theses.fr/1991LYO1M305.
Full textLeal, José. "Théorie et pratique de la codification dans l'oeuvre de Jean de Dieu d'Olivier (1753-1823)." Thesis, Paris Est, 2010. http://www.theses.fr/2010PEST2011.
Full textThe draft [of the] Civil Code written in 1789 by Jean de Dieu d'Olivier appears very close to the Civil Code of 1804. Also,it is possible to consider Olivier as one of the fathers of the French Civil Code
Hammerschmidt, Anna. "A strategic investment game with endogenous absorptive capacity." Inst. für Volkswirtschaftstheorie und -politik, WU Vienna University of Economics and Business, 2006. http://epub.wu.ac.at/106/1/document.pdf.
Full textSeries: Department of Economics Working Paper Series
Vilhena, Alyne Fonseca de. "Análise da imunoexpressão da podoplanina (D2-40), da proteína nuclear Ki-67 e da catepsina D-34 e suas relações com metástase em pacientes operados por tumor carcinoide típico broncopulmonar." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5156/tde-14082014-113714/.
Full textTypical bronchopulmonary carcinoid tumors are slow-growing tumors considered to be of low malignancy, a fact that often underscores their capacity to generate metastasis that leads to death. The literature does not contain any assessment of the metastatic potential that would allow for individualized and optimized therapy that could have a positive impact upon the survival rate of patients. Genetic and biomolecular studies are the most promising venues for better comprehension of the behavior and natural history of such tumors. The objective of this investigation was to analyze three immunomarkers associated to malignity phenotypes: D2-40, CD-34, and Ki-67, and to verify whether or not they are associated to metastasis. D2-40 is a specific marker of the proliferation of the lymphatic endothelium and allows for the quantification of lymphangiogenesis. CD-34 identifies the endothelial cells of micro vessels and quantifies angiogenesis. Ki-67 in turn is a marker of neoplasia cell proliferation. As additional information several clinical variables were scrutinized for their association to metastasis. Ninety-seven subjects were assessed herein. These had undergone surgery for typical bronchopulmonary carcinoid tumor and all had complied with a full 5-year follow-up period. The paraffin blocks containing the primary and metastatic tumors and the dried lymph nodes were recovered. Once the histologic diagnosis was confirmed immunohistochemical reactions were performed for D2-40, Ki-67, and CD-34. The variables demography, gender, age, tumor site, tumor size, compromised margin, total dissected lymph nodes and quantification of D2-40 (lymphatic area and density), Ki-67 and CD-34 markers were compared to 5 outcomes: lymphatic metastasis, metastasis in hilar, peribronchic and ipsilateral pulmonary lymph nodes (N1), metastasis in ipsilateral mediastinal lymph nodes (N2), haematogenic metastasis, and lymphatic or haematogenic metastasis. It was concluded that there is immunoexpression of D2-40, CD-34 and Ki-67 markers in typical bronchopulmonary carcinoid tumors, and their quantification was possible, but in this casuistic their relation to metastasis was not detected. Among the clinical variables that were investigated the compromised surgical margin presented association with haematogenic metastasis (Mann-Witney, p=0.03), and the male gender was boderline associated to lymphatic metastasis (p=0,051)
Fossat, Sébastien. "Plasties du ligament croisé antérieur (technique de Th. D. Rosenberg modifiée) rapport préliminaire à un an : à propos de 34 patients opérés dans le service de chirurgie orthopédique et traumatologique de l'H.I.A. Robert Picqué." Bordeaux 2, 1992. http://www.theses.fr/1992BOR2M188.
Full textEngin, Erjona. "Dynamic Analysis Of Flow In Two Dimensional Flow." Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/12609374/index.pdf.
Full textve (KL) decomposition is widely used in computational fluid dynamics to achieve reduced storage requirements or construction of relatively low-dimensional models. In this study the KL basis is extracted from the flow field obtained from the direct numerical simulation of the Poiseuille flow.
Yilgor, Pinar. "Sequential Growth Factor Delivery From Polymeric Scaffolds For Bone Tissue Engineering." Phd thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/3/12611188/index.pdf.
Full texthowever, the control of the cell organization and cell behavior to create fully functional 3-D constructs has not yet been achieved. To overcome these, activities have been concentrated on the development of multi-functional tissue engineering scaffolds capable of delivering the required bioactive agents to initiate and control cellular activities. The aim of this study was to prepare tissue engineered constructs composed of polymeric scaffolds seeded with mesenchymal stem cells (MSCs) carrying a nanoparticulate growth factor delivery system that would sequentially deliver the growth factors in order to mimic the natural bone healing process. To achieve this, BMP-2 and BMP-7, the osteogenic growth factors, were encapsulated in different polymeric nanocapsules (poly(lactic acid-co-glycolic acid) (PLGA) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV)) with different properties (degradation rates, crystallinity) and, therefore, different release rates to achieve the early release of BMP-2 followed by the release of BMP-7, as it is in nature. Initially, these nanoparticulate delivery systems were characterized and then the effect of single, simultaneous and sequential delivery of BMP-2 and BMP-7 from these delivery systems was studied in vitro using rat bone marrow MSCs. The effect of using these two growth factors in a sequential manner by mimicking their natural bioavailability timing was shown with maximized osteogenic activity results. BMP-2 loaded PLGA nanocapsules were subcutaneously implanted into Wistar rats and according to initial results, their biocompatibility as well as the positive effect of BMP-2 release on the formation of osteoclast-like cells was shown. To complete the construction of the bioactive scaffold, this nanoparticulate sequential delivery system was incorporated into two different types of polymeric systems
natural (chitosan) and synthetic (poly(&
#949
-caprolactone) (PCL)). 3-D fibrous scaffolds were produced using these materials by wet spinning and 3-D plotting. Incorporation of nanocapsules into 3-D chitosan scaffolds was studied by two different methods: incorporation within and onto chitosan fibers. Incorporation into 3-D PCL scaffolds was achieved by coating the nanocapsules onto the fibers of the scaffolds in an alginate layer. With both scaffold systems, incorporation of nanocapsule populations capable of delivering BMP-2 and BMP-7 in single, simultaneous and sequential fashion was achieved. As with free nanocapsules, the positive effect of sequential delivery on the osteogenic differentiation of MSCs was shown with both scaffold systems, creating multi-functional scaffolds capable of inducing bone healing.
Satan, Ali. "Les dispositifs juridiques de lutte contre le terrorisme et les garanties des droits fondamentaux, le cas de la France et des pays du Golfe." Thesis, Paris 1, 2019. http://www.theses.fr/2019PA01D089.
Full textIn the context of our study, we found that despite a certain degree of conformity of national and regional legislation with the UN strategy and the international conventions on the fight against terrorism, the fact remains that the effectiveness of these texts is relative, despite their number. The proof is the proliferation of terrorist attacks around the world and particularly in France. Indeed, in France, as elsewhere in the world, anti-terrorist measures are taken in the aftermath of the attacks, often under the effect of emotion and with the intention of calming and reassuring the population. However, we do not fight terrorism under the emotion or just to make the buzz and calm the spirits. In reality, only political will, far from economic interests and political calculations, can help deal with the terrorist phenomenon. Moreover, nobody knows, the causes and sources of terrorism are well identified and repressive is surely not the solution. Fighting terrorism means fighting its homes first. Worse still, the repressive and the adoption of measures undermining fundamental rights only feeds terrorism. Indeed, we have noted that in order to confront terrorism, states have put in place policies based on measures that infringe on fundamental rights. They are simply repressive policies where the rights of the accused are simply wiped out. Yet, terrorism is getting tougher and growing. To fight terrorism we must start by defending fundamental rights and freedoms. Indeed, it is injustice and misery that feeds terrorism
Choudhuri, Debjani Pal. "Community planning for intervention for victims of domestic violence adaption of the model from Kassel, Germany, for disadvantaged urban neighbourhoods in Pune City, India /." Kassel : Kassel Univ. Press, 2008. http://d-nb.info/99359347X/34.
Full textSpaiser, Olga. "Externe Demokratieförderung im post-sowjetischen Raum Handlungsmöglichkeiten und -grenzen der Organisation für Sicherheit und Zusammenarbeit in Europa (OSZE) in Kirgisistan /." München : Lehreinheit Prof. Dr. Mir A. Ferdowsi, Geschwister-Scholl-Inst. für Politische Wiss, 2009. http://d-nb.info/994127979/34.
Full textSaleh, Kutaiba. "Erweiterung eines Gefäßmodells zur Validierung von Gefäßmessalgorithmen in der Retina sowie theoretische und experimentelle Untersuchungen zu Messfehlerquellen der Gefäßanalyse." Ilmenau : Univ.-Verl, 2009. http://d-nb.info/994269560/34.
Full textHänlein, Andreas. "Die Heranziehung Unterhaltspflichtiger bei langwährender Pflegebedürftigkeit Volljähriger nach BSHG und BGB." Bielefeld : Gieseking, 1992. http://d-nb.info/988756072/34.
Full textAkmaz, Bülent L. "Medizinisch-technischer Fortschritt in Deutschland Innovationen in der Medizintechnik und ihre Regulierung im Rahmen der Gesetzlichen Krankenversicherung (GVK) /." München : Dr. Hut, 2009. http://d-nb.info/994405561/34.
Full textConstantinescu, Ovidiu Dragoş. "Wave sources and structures in the Earth's magnetosheath and adjacent regions." Katlenburg-Lindau : Copernicus, 2007. http://d-nb.info/994457952/34.
Full textWulfen, Yvonne von. "Wen und was erreicht Prävention in der Praxis? Dissemination und Effektivität des Triple-P-Elterngruppentrainings im Beratungsalltag in Deutschland /." Münster : Verl. für Psychotherapie, 2007. http://d-nb.info/994486979/34.
Full textTesch, Viola. "Gefügeoptimierte Instandsetzungsmörtel auf Calciumsulfat-Basis für die Anwendung im Außenbereich." Kassel : Kassel Univ. Press, 2007. http://d-nb.info/993586902/34.
Full textSteinbrück, Lutz. "Fremde Heimat Vechta in der Lyrik Rolf Dieter Brinkmanns /." Oldenburg : BIS-Verl. der Carl-von-Ossietzky-Univ, 2007. http://d-nb.info/993507662/34.
Full textKrudewig, Christiane. "Einfluss einer Staupevirusinfektion auf die In-vitro-Expression von Matrix-Metalloproteinasen in Gehirnzellpopulationen adulter Hunde." Gießen : DVG-Service, 2006. http://d-nb.info/994572492/34.
Full textZindl, Claudia. "Cryopreservation of Mexican gray wolf (Canis lupus baileyi) semen evaluation of different times and rates of pre-freeze cooling and Equex pasta supplementation ; in comparison with semen of the domestic dog and generic gray wolf (Canis lupus) /." Gießen : DVG-Service, 2006. http://d-nb.info/994572689/34.
Full textAlbrecht, Stefanie. "Prof. Dr. Hans Jöchle (1892-1968) ; ein Leben für den Hufbeschlag ; Quellen und Materialien zur Geschichte der Tierärztlichen Fakultät der Universität München /." Magdeburg : Docupoint-Verl, 2006. http://d-nb.info/994572956/34.
Full textBitter, Juliane. "Untersuchungen zur Eignung der B-Bild- und Farbdopplersonographie für die Diagnose von Puerperalstörungen beim Rind." Gießen : DVG-Service, 2006. http://d-nb.info/994573227/34.
Full textKöchling, Magdala Maria. "In-vitro-Untersuchungen über die Beeinflussung des NFkB-Signaltransduktionsweges nach Infektion von kaninen Keratinozyten und Makrophagen mit Staupe- und Hundeparainfluenzavirus." Gießen : DVG-Service, 2006. http://d-nb.info/994574126/34.
Full textOpora, Jeannette. "Die Wildbahngestüte Westfalens Geschichte, Entwicklung und Zukunft /." Bristol [u.a.] : Tenea, 2006. http://d-nb.info/994574460/34.
Full textGödde, Hildegard. "Die Krustenstrukturen am konvergenten Plattenrand Costa Ricas refraktionsseismische Messungen und ihre geologisch-geodynamische Interpretation /." Potsdam : Geoforschungszentrum, 1999. http://d-nb.info/99328034X/34.
Full textKloock, Joachim P. "Herstellung und Charakterisierung von Sensormembranen aus Chalkogenidglasschichten für den Einsatz als Schwermetallsensoren in Flüssigkeiten." Ilmenau : Univ.-Verl, 2009. http://d-nb.info/994269919/34.
Full textLeppert, Caroline. "Mehrphasenmodell für granulare Medien zur numerischen Untersuchung des Phasenübergangs bei der Entleerung von Silos." Braunschweig : Inst. für Statik, 2007. http://d-nb.info/994485506/34.
Full textPuff, Christina. "Matrix-Metalloproteinasen und ihre Inhibitoren bei der demyelinisierenden Staupeenzephalitis des Hundes eine molekularbiologische In-vivo- und In-vitro-Studie/ vorgelegt von Christina Puff." Gießen : DVG-Service, 2006. http://d-nb.info/994577842/34.
Full textSundermann, Till. "Echokardiografische Beurteilung der Herzkinetik in Ruhe und nach aktiver Belastung bei herzkranken Warmblutpferden." Gießen : DVG-Service, 2006. http://d-nb.info/994577931/34.
Full textVisscher, Christian Frank. "Untersuchungen (Feldstudie) zur Salmonellen-Prävalenz bei Mastschweinen unter dem Einfluss einer gröberen Futtervermahlung sowie von Futteradditiven (organische Säuren bzw. Kaliumdiformiat)." Gießen : DVG-Service, 2006. http://d-nb.info/994578172/34.
Full textVogelsang, Ingmar. "Die Tierzucht in der Zeit der Weimarer Republik und des Nationalsozialismus eine Dokumentation anhand ausgewählter veterinärmedizinischer Fachperiodika /." Berlin : Pro Business, 2007. http://d-nb.info/994578385/34.
Full textWerner-Keišs, Nicole. "Untersuchungen zur Expression von Strukturproteinen des Virus der Bornaschen Krankheit an intrazerebral infizierten Lewis-Ratten." Gießen : DVG-Service, 2006. http://d-nb.info/994578644/34.
Full textKramer, Katharina. "Experimentelle Infektion von TNFa-transgenen Mäusen mit dem Virus der Bornaschen Krankheit Charakterisierung der Entzündungsreaktion und der Virusreplikation /." Gießen : DVG-Service, 2006. http://d-nb.info/994578830/34.
Full textPekcec, Anton. "Untersuchungen zur Bedeutung der Neurogenese für die Entstehung von Epilepsien und Epilepsie-assoziierten Störungen." München : Verl. Dr. Hut, 2006. http://d-nb.info/994579160/34.
Full textNeddermann, Alexandra. "Das Phänomen der Bohrkanalerweiterung nach Ersatz des vorderen Kreuzbandes bei wachsenden Schafen eine interdisziplinäre Studie im Schafmodell /." Gießen : DVG-Service, 2008. http://d-nb.info/994580827/34.
Full textSeehusen, Frauke Antje. "Untersuchungen über Axonopathien und die Rolle des Neurotrophins BDNF bei der kaninen Staupeenzephalitis." Gießen : DVG-Service, 2006. http://d-nb.info/994602146/34.
Full textLohmeyer, Henning. "Optischer Einschluss, Lasing und Purcell-Effekt in Mikrosäulenkavitäten auf Basis breitlückiger Halbleiter." Berlin : Mensch- & -Buch-Verl, 2007. http://d-nb.info/994636245/34.
Full textHupp, Heike. "Qualitäts- und Prozesskontrolle gedruckter Interferenzeffektfarben erster Generation." Göttingen : Sierke, 2008. http://d-nb.info/994645422/34.
Full textBello, González Nazaret. "Spectropolarimetry of sunspot penumbrae." Katlenburg-Lindau : Copernicus, 2007. http://d-nb.info/994663536/34.
Full textKramar, Maxim I. "A feasibility study about the use of vector tomography for the reconstruction of the coronal magnetic field." Katlenburg-Lindau : Copernicus, 2006. http://d-nb.info/994664710/34.
Full textBuß, Astrid Johanne. "Differentielle Analyse des Peptidspektrums von Synovia und Blutplasma bei Gonarthrose." Giessen : VVB Laufersweiler, 2007. http://d-nb.info/994666063/34.
Full textWischhof, Lars. "Self-organizing communication in vehicular ad hoc networks." Aachen : Shaker, 2007. http://d-nb.info/994667388/34.
Full textWeber, Jörn. "Entwurf miniaturistischer Antennengruppen." Ilmenau : Univ.-Verl, 2009. http://d-nb.info/99459741X/34.
Full textAhlfeld, Birte. "Durchflusszytomentrische Bestimmungen von probiotischen Starterkulturen unter besonderer Berücksichtigung von Laktobazillen und Bifidobakterien." Gießen : DVG-Service, 2008. http://d-nb.info/989633136/34.
Full textThormann, Janina. "Diesel-Dampfreformierung in Mikrostrukturreaktoren." Karlsruhe : Forschungszentrum Karlsruhe, 2009. http://d-nb.info/99396785X/34.
Full textWundrak, Linda. "Developmental states als Modell Chancen und Hindernisse der neuen südafrikanischen Entwicklungsstrategie /." München : Lehreinheit Prof. Dr. Mir A. Ferdowsi, Geschwister-Scholl-Inst. für Politische Wiss, 2009. http://d-nb.info/994407785/34.
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