Relevant bibliographies by topics / ° CzT SPECT camera

Academic literature on the topic '° CzT SPECT camera'

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Published: 7 July 2024

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Journal articles on the topic "° CzT SPECT camera":

1

Bouchareb, Yassine, Afrah AlSaadi, Jawa Zabah, Anjali Jain, Aziza Al-Jabri, Peter Phiri, Jian Qing Shi, Gayathri Delanerolle, and Srinivasa Rao Sirasanagandla. "Technological Advances in SPECT and SPECT/CT Imaging." Diagnostics 14, no. 13 (July 4, 2024): 1431. http://dx.doi.org/10.3390/diagnostics14131431.

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Single photon emission tomography/computed tomography (SPECT/CT) is a mature imaging technology with a dynamic role in the diagnosis and monitoring of a wide array of diseases. This paper reviews the technological advances, clinical impact, and future directions of SPECT and SPECT/CT imaging. The focus of this review is on signal amplifier devices, detector materials, camera head and collimator designs, image reconstruction techniques, and quantitative methods. Bulky photomultiplier tubes (PMTs) are being replaced by position-sensitive PMTs (PSPMTs), avalanche photodiodes (APDs), and silicon PMs to achieve higher detection efficiency and improved energy resolution and spatial resolution. Most recently, new SPECT cameras have been designed for cardiac imaging. The new design involves using specialised collimators in conjunction with conventional sodium iodide detectors (NaI(Tl)) or an L-shaped camera head, which utilises semiconductor detector materials such as CdZnTe (CZT: cadmium–zinc–telluride). The clinical benefits of the new design include shorter scanning times, improved image quality, enhanced patient comfort, reduced claustrophobic effects, and decreased overall size, particularly in specialised clinical centres. These noticeable improvements are also attributed to the implementation of resolution-recovery iterative reconstructions. Immense efforts have been made to establish SPECT and SPECT/CT imaging as quantitative tools by incorporating camera-specific modelling. Moreover, this review includes clinical examples in oncology, neurology, cardiology, musculoskeletal, and infection, demonstrating the impact of these advancements on clinical practice in radiology and molecular imaging departments.
2

Cantoni, Valeria, Roberta Green, Carlo Ricciardi, Roberta Assante, Leandro Donisi, Emilia Zampella, Giuseppe Cesarelli, et al. "Comparing the Prognostic Value of Stress Myocardial Perfusion Imaging by Conventional and Cadmium-Zinc Telluride Single-Photon Emission Computed Tomography through a Machine Learning Approach." Computational and Mathematical Methods in Medicine 2021 (October 16, 2021): 1–8. http://dx.doi.org/10.1155/2021/5288844.

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We compared the prognostic value of myocardial perfusion imaging (MPI) by conventional- (C-) single-photon emission computed tomography (SPECT) and cadmium-zinc-telluride- (CZT-) SPECT in a cohort of patients with suspected or known coronary artery disease (CAD) using machine learning (ML) algorithms. A total of 453 consecutive patients underwent stress MPI by both C-SPECT and CZT-SPECT. The outcome was a composite end point of all-cause death, cardiac death, nonfatal myocardial infarction, or coronary revascularization procedures whichever occurred first. ML analysis performed through the implementation of random forest (RF) and k -nearest neighbors (KNN) algorithms proved that CZT-SPECT has greater accuracy than C-SPECT in detecting CAD. For both algorithms, the sensitivity of CZT-SPECT (96% for RF and 60% for KNN) was greater than that of C-SPECT (88% for RF and 53% for KNN). A preliminary univariate analysis was performed through Mann-Whitney tests separately on the features of each camera in order to understand which ones could distinguish patients who will experience an adverse event from those who will not. Then, a machine learning analysis was performed by using Matlab (v. 2019b). Tree, KNN, support vector machine (SVM), Naïve Bayes, and RF were implemented twice: first, the analysis was performed on the as-is dataset; then, since the dataset was imbalanced (patients experiencing an adverse event were lower than the others), the analysis was performed again after balancing the classes through the Synthetic Minority Oversampling Technique. According to KNN and SVM with and without balancing the classes, the accuracy ( p value = 0.02 and p value = 0.01) and recall ( p value = 0.001 and p value = 0.03) of the CZT-SPECT were greater than those obtained by C-SPECT in a statistically significant way. ML approach showed that although the prognostic value of stress MPI by C-SPECT and CZT-SPECT is comparable, CZT-SPECT seems to have higher accuracy and recall.
3

Weng, Fenghua, Srijeeta Bagchi, Yunlong Zan, Qiu Huang, and Youngho Seo. "An energy-optimized collimator design for a CZT-based SPECT camera." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 806 (January 2016): 330–39. http://dx.doi.org/10.1016/j.nima.2015.09.115.

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Duvall, W. Lane, Lori B. Croft, Tapan Godiwala, Eric Ginsberg, Titus George, and Milena J. Henzlova. "Reduced isotope dose with rapid SPECT MPI imaging: Initial experience with a CZT SPECT camera." Journal of Nuclear Cardiology 17, no. 6 (November 12, 2010): 1009–14. http://dx.doi.org/10.1007/s12350-010-9215-5.

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Duvall, W. Lane, Lori B. Croft, Eric S. Ginsberg, Andrew J. Einstein, Krista A. Guma, Titus George, and Milena J. Henzlova. "Reduced isotope dose and imaging time with a high-efficiency CZT SPECT camera." Journal of Nuclear Cardiology 18, no. 5 (April 29, 2011): 847–57. http://dx.doi.org/10.1007/s12350-011-9379-7.

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Hansen, Maria Normand, Christian Haarmark, Bent Kristensen, and Bo Zerahn. "An Algorithm for Individual Dosage in Cadmium–Zinc–Telluride SPECT-Gated Radionuclide Angiography." Diagnostics 11, no. 12 (December 4, 2021): 2268. http://dx.doi.org/10.3390/diagnostics11122268.

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The aim of the present study was to test an individualised dose without compromising the ease of analysing data when performing equilibrium radionuclide angiography (ERNA) using cadmium–zinc–telluride (CZT) SPECT. From March 2018 to January 2019, 1650 patients referred for ERNA received either an individualised dose of 99mTc-labeled human serum albumin (HSA) according to their age, sex, height, and weight (n = 1567), or a standard dose of 550 MBq (n = 83). The target count rate (CRT) was reduced every two months from 2.7 to 1.0 kcps. A final test with a CRT of 1.7 kcps was run for three months to test whether an agreement within 2% points for the determination of LVEF, on the basis of only two analyses, was obtainable in at least 95% of acquisitions. All the included ERNAs were performed on a dedicated cardiac CZT SPECT camera. When using the algorithm for an individualised dose, we found that agreement between the measured and predicted count rate was 80%. With a CRT of 1.7 kcps, the need for more than two analyses to obtain sufficient agreement for LVEF was 4.9%. Furthermore, this resulted in a mean dose reduction from 550 to 258 MBq. Patients’ weight, height, sex, and age can, therefore, be used for individualising a tracer dose while reducing the mean dose.
7

Yoo, Ik Dong, In Young Jo, Geum Cheol Jeong, Yong Kyun Won, Du Shin Jeong, and Sang Mi Lee. "Quantitative Scintigraphy Imaging of Lingual Raynaud’s Phenomenon Using 3-Dimensional-Ring Cadmium-Zinc-Telluride Single-Photon Emission Computed Tomography/Computed Tomography." Tomography 8, no. 4 (August 17, 2022): 2042–48. http://dx.doi.org/10.3390/tomography8040171.

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Perfusion scintigraphy with the acquisition of planar blood flow and pool images of bilateral hands has been used to aid diagnosis and to evaluate treatment response to Raynaud’s phenomenon (decreased blood flow to hand or foot). However, because of the difficulty in imaging the tongue area with a conventional gamma camera, perfusion scintigraphy imaging of patients with lingual Raynaud’s phenomenon has yet to be reported. Here, we report the case of a 59-year-old man with lingual Raynaud’s phenomenon in which blood pool imaging of the tongue was performed using three-dimensional (3D)-ring cadmium-zinc-telluride (CZT) single-photon emission computed tomography/computed tomography (SPECT/CT). During follow-up, the patient’s lingual symptoms had worsened, and follow-up blood pool SPECT/CT images also revealed decreased blood pool uptake of the tongue, showing a decreased blood pool of more than 25% on quantitative analysis. This case suggests that blood pool imaging of the tongue using 3D-ring CZT SPECT/CT has clinical significance in evaluating patients with lingual Raynaud’s phenomenon.
8

Hindorf, Cecilia, Jenny Oddstig, Fredrik Hedeer, Magnus J. Hansson, Jonas Jögi, and Henrik Engblom. "Importance of correct patient positioning in myocardial perfusion SPECT when using a CZT camera." Journal of Nuclear Cardiology 21, no. 4 (May 8, 2014): 695–702. http://dx.doi.org/10.1007/s12350-014-9897-1.

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Lima, Ronaldo, Thais Peclat, Thalita Soares, Caio Ferreira, Ana Carolina Souza, and Gabriel Camargo. "Comparison of the prognostic value of myocardial perfusion imaging using a CZT-SPECT camera with a conventional anger camera." Journal of Nuclear Cardiology 24, no. 1 (August 10, 2016): 245–51. http://dx.doi.org/10.1007/s12350-016-0618-9.

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Piatkova, Yuliya, Pierre Payoux, Caroline Boursier, Manon Bordonne, Veronique Roch, Pierre-Yves Marie, Gabriela Hossu, Laëtitia Imbert, and Antoine Verger. "Prospective Paired Comparison of 123I-FP-CIT SPECT Images Obtained With a 360°-CZT and a Conventional Camera." Clinical Nuclear Medicine 47, no. 1 (January 2022): 14–20. http://dx.doi.org/10.1097/rlu.0000000000003969.

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Journal articles

Dissertations / Theses on the topic "° CzT SPECT camera":

1

Desmonts, Cedric. "Apport des technologies TEMP et TEP numériques en médecine nucléaire dans le domaine de l’oncologie clinique et préclinique." Electronic Thesis or Diss., Normandie, 2023. http://www.theses.fr/2023NORMC429.

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La médecine nucléaire a connu ces dernières années d’importantes évolutions technologiques grâce à l’arrivée de caméras dites numériques, qui reposent sur l’utilisation de détecteurs semi-conducteurs. En tomographie d’émission monophotonique (TEMP), cette technologie a d’abord été introduite sur des caméras CzT dédiées à l’exploration cardiaque. Plus récemment, des caméras CzT 360° à champ de vue étendu ont été développées pour permettre des explorations tomographiques corps entier. De même, les caméras utilisées en tomographie par émission de positon (TEP) ont connu une transition vers des technologies numériques grâce à l’utilisation de nouveaux détecteurs SiPM. Ce travail a permis d’évaluer les performances de ces caméras TEMP et TEP numériques en médecine nucléaire dans le domaine de l’oncologie clinique et préclinique. Nous avons ainsi démontré les gains en sensibilité, en résolution en énergie et en contraste image obtenus à l’aide des caméras CzT 360° par rapport aux caméras de Anger conventionnelles. Il a également été démontré la faisabilité d’utiliser ce type de caméra, initialement développée pour l’homme, pour réaliser de l’imagerie chez le petit animal. Dans un second temps, nous avons évalué sur fantôme les caméras TEP SiPM pour une utilisation en préclinique. Nous avons ainsi mesuré des performances s’approchant de celles obtenues avec des caméras microTEP dédiées, en permettant l’imagerie simultanée de quatre animaux, et montré la possibilité de réaliser de la quantification avec une précision suffisante en oncologie préclinique
In recent years, nuclear medicine has undergone significant technological advances with the introduction of digital cameras based on the use of semiconductor detectors. In single-photon emission computed tomography (SPECT), this technology was first introduced on dedicated cardiac CzT cameras. More recently, 360° CzT cameras with extended field-of-view have been developed to enable whole-body tomographic explorations. Similarly, the cameras used in positron emission tomography (PET) have undergone a transition to digital technologies thanks to the use of new SiPM-based detectors. This work has allowed for the evaluation of the performance of these digital SPECT and PET cameras in nuclear medicine, within the field of clinical and preclinical oncology. We have thus demonstrated the improvements in sensitivity, energy resolution, and image contrast achieved through the use of 360° CzT cameras compared to conventional Anger cameras. Additionally, we demonstrated the feasibility of using this type of camera developed for humans, to perform preclinical imaging in small animals. Furthermore, we have evaluated SiPM-based PET cameras using phantoms for potential preclinical applications. We have thus measured performance approaching that obtained with dedicated microPET cameras, enabling simultaneous imaging of four animals, and demonstrated the ability to perform accurate quantification in preclinical oncology
2

Robert, Charlotte. "Optimisation de l'architecture HiSens, une nouvelle architecture de gamma-caméra CdZnTe haute sensibilité pour l'imagerie clinique." Paris 11, 2010. http://www.theses.fr/2010PA112232.

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Dans le but de dépasser le compromis résolution spatiale/sensibilité des gamma-caméras d'Anger, l'architecture HiSens est étudiée depuis plusieurs années. Cette architecture, basée sur l'utilisation d'un détecteur semi-conducteur CdZnTe, exploite la localisation 3D précise des interactions au sein du détecteur. Cette thèse s'inscrit dans ce cadre. Tout d'abord, une méthodologie de quantification de la qualité du volume reconstruit est mise en place. Cette étape permet de valider en mode planaire, par la simulation ainsi que par l'expérience, les intérêts potentiels de l'architecture. Afin d'en optimiser les paramètres, un outil de calcul de DQE (Detective Quantum Efficiency), adapté à l'imagerie gamma, est développé en mode d'acquisition planaire. Une optimisation de l'ouverture du collimateur pour deux applications, cardiaque et scintimammographique, est réalisée. Elle montre qu'un gain supérieur à un facteur 3 en sensibilité peut être obtenu pour une distance source-collimateur de 5 cm, à résolution identique voire meilleure, grâce à l'architecture HiSens. Dans le cadre de cette étude, le paramètre distance collimateur-détecteur est ajusté. Ce paramètre, qui permet un gain notable en qualité image pour les objets hautes fréquences, fait aujourd'hui l'objet d'un brevet et d'une validation expérimentale. Finalement, un programme de calcul de DQE en mode tomographique est développé. Celui-ci permet de caractériser, par exemple, la variation des performances dans le champ de vue. Grâce à ce programme, une méthodologie d'optimisation des caractéristiques système pour l'application cardiaque en mode tomographique est introduite. Elle clôture ces travaux de thèse
To overcome the Anger camera spatial resolution/sensitivity trade-off, the HiSens architecture has been studied for several years. This architecture, based on pixelated CZT detectors, takes advantage of the accurate 3D localization of the interactions inside the detector. This work is dedicated to this architecture. First, a quantification methodology is introduced. This step allows preliminary simulation-based and experimental evaluation of the architecture in planar acquisition mode. A DQE (Detective Quantum Efficiency) calculation tool, aiming at optimizing the HiSens parameters in planar acquisition mode, is then proposed and used for two applications (cardiac imaging and scintimammography). Lt shows that, considering a 5 cm source-collimator distance, the system sensitivity can be increased by 3 while maintaining or improving the spatial resolution thanks to the HiSens architecture. Ln this study, the collimator-to-detector distance parameter is made scalable. We show that its adjustment can advantageously increase the high frequency content of the reconstructed images. The effect of this parameter is experimentally validated in this work and has been besides patented. Finally, a SPECT DQE calculation tool is developed. This one, permitting to describe the system performances inside the field-of-view, is used, at the end of the work, to suggest a methodology allowing to determine the optimal collimation parameters for cardiac SPECT applications
3

Imbert, Laëtitia. "Analyse et modélisation des performances d'un nouveau type de détecteur en médecine nucléaire : du détecteur Anger au détecteur semi-conducteur." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0279/document.

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La tomoscintigraphie myocardique est considérée comme un examen de référence pour le diagnostic et l'évaluation de la maladie coronarienne. Mise au point dans les années 1980, cette technique est en pleine mutation depuis l'arrivée de nouvelles caméras à semi-conducteurs. Deux caméras à semi-conducteurs, dédiées à la cardiologie nucléaire et utilisant des détecteurs de Cadmium Zinc Telluride sont actuellement commercialisées : la Discovery NM-530c (General Electric) et la DSPECT (Spectrum Dynamics). Les performances de ces caméras CZT ont été évaluées : 1) à la fois sur fantôme et sur des examens d'effort provenant de patients à faible probabilité de maladie coronaire, et 2) avec les paramètres d'acquisition et de reconstruction utilisés en clinique. Les résultats ont démontré la nette supériorité des caméras CZT en termes de sensibilité de détection, de résolution spatiale et de rapport contraste sur bruit par rapport à la génération de caméras d'Anger. Ces propriétés vont permettre de diminuer très fortement les temps d'acquisition et les activités injectées, tout en améliorant la qualité des images. Néanmoins, on connaît encore mal les limites et possibles artéfacts liés à la géométrie particulière d'acquisition. C'est pourquoi nous avons développé, avec la plateforme de simulations Monte Carlo GATE, un simulateur numérique spécifique de la caméra DSPECT. Nous avons pu ensuite le valider en comparant des données effectivement enregistrées aux données simulées. Ce simulateur pourrait aider à optimiser les protocoles de reconstruction et d'acquisition, en particulier les protocoles les plus complexes (acquisitions double traceur, études cinétiques)
Myocardial single-photon emission computed tomography (SPECT) is considered as the gold standard for the diagnosis of coronary artery disease. Developed in the 1980s with rotating Anger gamma-cameras, this technique could be dramatically enhanced by new imaging systems working with semi-conductor detectors. Two semiconductor cameras, dedicated to nuclear cardiology and equipped with Cadmium Zinc Telluride detectors, have been recently commercialized: the Discovery NM- 530c (General Electric) and the DSPECT (Spectrum Dynamics). The performances of these CZT cameras were compared: 1) by a comprehensive analysis of phantom and human SPECT images considered as normal and 2) with the parameters commonly recommended for SPECT recording and reconstruction. The results show the superiority of the CZT cameras in terms of detection sensitivity, spatial resolution and contrast-to-noise ratio, compared to conventional Anger cameras. These properties might lead to dramatically reduce acquisition times and/or the injected activities. However, the limits of these new CZT cameras, as well as the mechanism of certain artefacts, remain poorly known. That?s why we developed, with the GATE Monte Carlo simulation plateform, a specific simulator of the DSPECT camera. We validated this simulator by comparing actually recorded data with simulated data. This simulator may yet be used to optimize the recorded and reconstruction processes, especially for complex protocols such as simultaneous dual-radionuclide acquisition and kinetics first-pass studies
4

Imbert, Laëtitia. "Analyse et modélisation des performances d'un nouveau type de détecteur en médecine nucléaire : du détecteur Anger au détecteur semi-conducteur." Electronic Thesis or Diss., Université de Lorraine, 2012. http://www.theses.fr/2012LORR0279.

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La tomoscintigraphie myocardique est considérée comme un examen de référence pour le diagnostic et l'évaluation de la maladie coronarienne. Mise au point dans les années 1980, cette technique est en pleine mutation depuis l'arrivée de nouvelles caméras à semi-conducteurs. Deux caméras à semi-conducteurs, dédiées à la cardiologie nucléaire et utilisant des détecteurs de Cadmium Zinc Telluride sont actuellement commercialisées : la Discovery NM-530c (General Electric) et la DSPECT (Spectrum Dynamics). Les performances de ces caméras CZT ont été évaluées : 1) à la fois sur fantôme et sur des examens d'effort provenant de patients à faible probabilité de maladie coronaire, et 2) avec les paramètres d'acquisition et de reconstruction utilisés en clinique. Les résultats ont démontré la nette supériorité des caméras CZT en termes de sensibilité de détection, de résolution spatiale et de rapport contraste sur bruit par rapport à la génération de caméras d'Anger. Ces propriétés vont permettre de diminuer très fortement les temps d'acquisition et les activités injectées, tout en améliorant la qualité des images. Néanmoins, on connaît encore mal les limites et possibles artéfacts liés à la géométrie particulière d'acquisition. C'est pourquoi nous avons développé, avec la plateforme de simulations Monte Carlo GATE, un simulateur numérique spécifique de la caméra DSPECT. Nous avons pu ensuite le valider en comparant des données effectivement enregistrées aux données simulées. Ce simulateur pourrait aider à optimiser les protocoles de reconstruction et d'acquisition, en particulier les protocoles les plus complexes (acquisitions double traceur, études cinétiques)
Myocardial single-photon emission computed tomography (SPECT) is considered as the gold standard for the diagnosis of coronary artery disease. Developed in the 1980s with rotating Anger gamma-cameras, this technique could be dramatically enhanced by new imaging systems working with semi-conductor detectors. Two semiconductor cameras, dedicated to nuclear cardiology and equipped with Cadmium Zinc Telluride detectors, have been recently commercialized: the Discovery NM- 530c (General Electric) and the DSPECT (Spectrum Dynamics). The performances of these CZT cameras were compared: 1) by a comprehensive analysis of phantom and human SPECT images considered as normal and 2) with the parameters commonly recommended for SPECT recording and reconstruction. The results show the superiority of the CZT cameras in terms of detection sensitivity, spatial resolution and contrast-to-noise ratio, compared to conventional Anger cameras. These properties might lead to dramatically reduce acquisition times and/or the injected activities. However, the limits of these new CZT cameras, as well as the mechanism of certain artefacts, remain poorly known. That?s why we developed, with the GATE Monte Carlo simulation plateform, a specific simulator of the DSPECT camera. We validated this simulator by comparing actually recorded data with simulated data. This simulator may yet be used to optimize the recorded and reconstruction processes, especially for complex protocols such as simultaneous dual-radionuclide acquisition and kinetics first-pass studies

Books on the topic "° CzT SPECT camera":

1

Garcia, Ernest V., James R. Galt, and Ji Chen. SPECT and PET Instrumentation. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0003.

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Nuclear cardiac imaging is solidly based on many branches of science and engineering, including nuclear, optical and mathematical physics, electrical and mechanical engineering, chemistry and biology. This chapter uses principles from these scientific fields to provide an understanding of both the signals used, and the imaging system that captures these signals. Nuclear cardiology’s signals are the x-rays or ?-rays photons emitted from a radioactive tracer and its imaging systems are either single-photon emission computed tomography (SPECT) or positron emission tomography (PET) cameras. This combination has met with remarkable success in clinical cardiology. This success is due to the combination of sophisticated electronic nuclear instruments with a highly specific and thus powerful signal. The signal is as important as or more important than the imaging system. There is a misconception that cardiac magnetic resonance (CMR) cardiac computed tomography (CCT) and echocardiography are superior to nuclear cardiology imaging because of their superior spatial resolution. Yet, in detecting perfusion defects what is really necessary is superior contrast resolution. It is this superior contrast resolution that allows us to differentiate between normal and hypoperfused myocardium facilitating the visual analysis of nuclear cardiology perfusion images. Because these objects are bright compared to the background radioactivity, computer algorithms have been developed that allow us to automatically and objectively process and quantify our images. This chapter explains many of the important scientific principles necessary to understand nuclear cardiology imaging in general, i.e., how these sophisticated imaging systems detect the radiation emitted from the radiotracers.
2

Kelion, Andrew, Parthiban Arumugam, and Nikant Sabharwal. Nuclear Cardiology (Oxford Specialist Handbooks in Cardiology). Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198759942.001.0001.

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Readable, practical, and concise, the Oxford Specialist Handbook in Nuclear Cardiology is a self-contained guide to this cardiac imaging subspecialty. Including both technical and clinical aspects, it provides a foundation of essential knowledge common to practitioners from any background.This title covers radiation physics, biology and protection, and addresses all areas of imaging including the design and operation of the gamma camera (including solid-state cameras), single photon emission computed tomography (SPECT) acquisition and processing, and image interpretation and writing of reports. Stress testing and radiopharmaceuticals are explained in detail, as is the evidence base underpinning myocardial perfusion scintigraphy. Newer radionuclide imaging techniques are well covered (e.g. phosphate scintigraphy in cardiac amyloidosis), as is the expanding field of cardiac positron emission tomography (PET). Fully updated with coverage of new indications for gamma camera imaging, increased focus on attenuation correction and SPECT-CT, and detail on the design use and clinical implications of solid-state gamma cameras throughout, this second edition of the essential text for nuclear cardiology trainees and practitioners is fully illustrated with colour plates to aid clinical practice. Presented in the bestselling Oxford Handbook format, Nuclear Cardiology provides core knowledge for those training in the subspecialty, whether at a basic or advanced level or from a medical or technical background, and is a key resource for those seeking to accredit in the subspecialty.

Book chapters on the topic "° CzT SPECT camera":

1

Lawson, Richard S. "Gamma Camera SPECT." In Practical SPECT/CT in Nuclear Medicine, 47–75. London: Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-4703-9_4.

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Willson, Tamar. "Gamma Camera Artifacts." In Clinical Atlas of Bone SPECT/CT, 21–24. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-26449-8_5.

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Willson, Tamar. "Gamma Camera Artifacts." In Clinical Atlas of Bone SPECT/CT, 1–3. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-030-32256-4_5-1.

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Oddstig, Jenny, David Minarik, and Mikael Gunnarsson. "Quality Control of Gamma Cameras, SPECT/CT and PET/CT Units." In Radiation Protection in Nuclear Medicine, 71–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-31167-3_6.

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Volterrani, Duccio, Federica Guidoccio, Giulia Puccini, and Sara Mazzarri. "Image Acquisition and Processing with Gamma Cameras Including Integrated SPECT/CT and Dedicated Gamma Cameras." In Nuclear Medicine Textbook, 173–86. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-95564-3_7.

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Avram, Anca M. "Radioiodine Theranostics of Differentiated Thyroid Carcinoma." In Integrated Diagnostics and Theranostics of Thyroid Diseases, 111–27. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-35213-3_7.

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AbstractCurrent management of patients with thyroid cancer requires a risk-adapted approach to treatment and multidisciplinary cooperation. Routine use of 131-I administration after total thyroidectomy is no longer recommended as this approach has been challenged by evidence that remnant ablation does not improve survival in low-risk patients. However, therapeutic 131-I administration in intermediate- and high-risk patients demonstrated significant benefits in improving overall survival. Radioiodine (131-I Na-I) is the classic agent used for the diagnosis and treatment of differentiated thyroid cancer (DTC) based on sodium–iodine symporter expression in normal and neoplastic thyroid tissues permitting the integration of diagnostic imaging and therapeutics using the same radionuclide (i.e., theranostics) targeting specific characteristics of tumor biology. Radioiodine theragnostics involves the acquisition of pre-ablation diagnostic scans (Dx Scans) to guide patient-individualized targeted 131-I therapy with goal of maximizing the benefits of the first therapeutic 131-I administration. Current imaging technology with hybrid SPECT/CT gamma camera systems has improved the capability of diagnostic radioiodine scintigraphy for identifying regional and distant metastatic disease and this imaging information can be used for 131-I treatment planning and delivery of activity-adjusted 131-I therapy for achieving intended treatment goals (e.g., remnant ablation, adjuvant treatment, and treatment of known disease). The goal of radioiodine theragnostics is to optimize the balance between 131-I therapeutic efficacy and potential side effects on non-target tissues. This chapter summarizes the new concepts and essential information at the core of multidisciplinary DTC management, which emphasizes individualization of 131I therapy according to the patient’s risk for tumor recurrence to maximize benefit and minimize morbidity.
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de Oliveira Brito, Juliana Brenande, Gary R. Small, Kathryn J. Ascah, R. Glenn Wells, and Terrence D. Ruddy. "Measurement of Myocardial Blood Flow by SPECT." In Nuclear Cardiac Imaging Companion Atlas, 30–31. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197521434.003.0010.

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Abstract Stress MPI with SPECT and PET is widely used for diagnosis and determining prognosis in patients with suspected or known CAD. However, a major limitation of MPI is the use of relative perfusion for diagnosis of obstructive CAD and leads to underestimation of the extent of obstructive CAD. However, MBF and MFR can be measured with PET and provide additional diagnostic and prognostic value over relative PET MPI. Similarly, SPECT measurement of MBF may improve the clinical value of SPECT and greatly increase the availability and use of MBF with MPI. The accuracy of CZT SPECT measurement of MBF has been validated in clinical evaluations in patients undergoing coronary angiography and PET imaging. Reduced global stress MBF and MFR can identify the presence of severe MVD. Regional reductions in stress MBF and MFR have high diagnostic accuracy for specific vessel CAD. Reduced global and regional SPECT MFR can predict reduced global and regional PET MFR. SPECT measurement of MBF has good day-to-day repeatability and interobserver variability. We describe the use of SPECT MBF at the University of Ottawa Heart Institute, including image acquisition and processing and clinical interpretation of test results with case examples. The clinical use of SPECT MBF is in the early stages of implementation. Protocols including radiotracers, camera systems and software need to be standardized. Multicenter studies are necessary to better define the diagnostic value of CZT SPECT MBF for obstructive CAD and the incremental prognostic value of SPECT MBF measurement compared to relative MPI.
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Brito, Juliana Brenande de Oliveira, Gary R. Small, Kathryn J. Ascah, R. Glenn Wells, and Terrence D. Ruddy. "Measurement of Myocardial Blood Flow by SPECT." In Nuclear Cardiac Imaging, edited by Ami E. Iskandrian and Fadi G. Hage, 208–29. 6th ed. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780190095659.003.0010.

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Abstract:
Abstract Stress MPI with SPECT and PET is widely used for diagnosis and determining prognosis in patients with suspected or known CAD. However, a major limitation of MPI is the use of relative perfusion for diagnosis of obstructive CAD and leads to underestimation of the extent of obstructive CAD. However, MBF and MFR can be measured with PET and provide additional diagnostic and prognostic value over relative PET MPI. Similarly, SPECT measurement of MBF may improve the clinical value of SPECT and greatly increase the availability and use of MBF with MPI. The accuracy of CZT SPECT measurement of MBF has been validated in clinical evaluations in patients undergoing coronary angiography and PET imaging. Reduced global stress MBF and MFR can identify the presence of severe MVD. Regional reductions in stress MBF and MFR have high diagnostic accuracy for specific vessel CAD. Reduced global and regional SPECT MFR can predict reduced global and regional PET MFR. SPECT measurement of MBF has good day-to-day repeatability and interobserver variability. We describe the use of SPECT MBF at the University of Ottawa Heart Institute, including image acquisition and processing and clinical interpretation of test results with case examples. The clinical use of SPECT MBF is in the early stages of implementation. Protocols including radiotracers, camera systems and software need to be standardized. Multicenter studies are necessary to better define the diagnostic value of CZT SPECT MBF for obstructive CAD and the incremental prognostic value of SPECT MBF measurement compared to relative MPI.
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Merlin N. J, Dr. "ADVANCEMENTS IN NUCLEAR MEDICINE: UNVEILING THE FUTURE OF DIAGNOSTICS AND THERAPEUTICS." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 1, 42–57. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bipn1p1ch4.

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The historical evolution of nuclear medicine, rooted in the early 20th century, has transformed modern healthcare by integrating radioactive isotopes to visualize and understand physiological processes within the human body. Irene Joliot-Curie and Frederic Joliot's discovery of artificial radioactivity in 1938 marked a pivotal moment, while the 1950s saw the advent of the gamma camera by Hal Anger, ushering in an era of advanced imaging techniques. Positron emission tomography (PET) emerged in the 1970s, expanding diagnostic capabilities. Nuclear medicine's role in healthcare is paramount, aiding early disease detection, staging, and treatment monitoring. The principles of nuclear medicine hinge on radiopharmaceuticals emitting gamma rays or positrons, targeting specific tissues. Unlike anatomical imaging, nuclear medicine focuses on functionality, playing a critical role in oncology, cardiology, neurology, endocrinology, nephrology, and pulmonology. The concept of theranostics, combining diagnostic imaging with targeted radionuclide therapy, exemplifies personalized medicine. Radiopharmaceuticals like Technetium-99m, Fluorine-18, Iodine-131, and Yttrium-90 have diverse applications. Production methods involve cyclotrons or generators, ensuring stringent quality control. Diagnostic applications span myocardial perfusion imaging, PET for various studies, bone scintigraphy, thyroid scans, and more. Therapeutic applications include radioiodine therapy and targeted radionuclide therapy. Nuclear medicine imaging techniques, such as gamma cameras, Single-Photon Emission Computed Tomography (SPECT), and Positron Emission Tomography (PET), capture the distribution of radiopharmaceuticals. Hybrid imaging systems (PET/CT, SPECT/CT) merge functional and anatomical data, enhancing diagnostic accuracy. Ongoing advancements in imaging technology, theranostics, and radiopharmaceutical research present promising future prospects. However, challenges, such as radiation exposure and integration into healthcare systems, persist. Addressing these challenges, coupled with evolving technologies, positions nuclear medicine as a pivotal force in personalized medicine and targeted therapy.
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Balcerzyk, M., L. Caballero, C. Correcher, A. Gonzalez, C. Vazquez, J. L. Rubio, G. Kontaxakis, M. A. Pozo, and J. M. Benlloch. "Virtual PET Scanner – From Simulation in GATE to a Final Multiring Albira PET/SPECT/CT Camera." In Positron Emission Tomography - Current Clinical and Research Aspects. InTech, 2012. http://dx.doi.org/10.5772/30429.

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Conference papers on the topic "° CzT SPECT camera":

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Imbert, L., P. Y. Marie, E. Galbrun, S. Poussier, D. Wolf, G. Karcher, and A. Noel. "Initial assessment of the Monte-Carlo simulation of SPECT recording with the new region-centric CZT “DSPECT” camera." In 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference (2012 NSS/MIC). IEEE, 2012. http://dx.doi.org/10.1109/nssmic.2012.6551581.

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Antic, Vojislav, Nebojsa Petrovic, Jelena Petrovic, and Vera Artiko. "Possibilities of modern CZT SPECT-CT gamma cameras in NET diagnostics." In RAD Conference. RAD Centre, 2023. http://dx.doi.org/10.21175/rad.abstr.book.2023.20.1.

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Cao, Liji, and Jorg Peter. "Slit-slat collimator equipped gamma camera for whole-mouse SPECT-CT imaging." In 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (2011 NSS/MIC). IEEE, 2011. http://dx.doi.org/10.1109/nssmic.2011.6153865.

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Alhassen, Fares, Haris Kudrolli, Bipin Singh, Sangtaek Kim, Youngho Seo, Robert G. Gould, and Vivek V. Nagarkar. "A preclinical SPECT camera with depth-of-interaction compensation using a focused-cut scintillator." In SPIE Medical Imaging, edited by Norbert J. Pelc, Ehsan Samei, and Robert M. Nishikawa. SPIE, 2011. http://dx.doi.org/10.1117/12.878324.

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Mann, Steve D., and Martin P. Tornai. "Initial evaluation of a modified dual-energy window scatter correction method for CZT-based gamma cameras for breast SPECT." In SPIE Medical Imaging, edited by Sébastien Ourselin and Martin A. Styner. SPIE, 2015. http://dx.doi.org/10.1117/12.2082195.

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Weiss Cohen, Miri, John A. Kennedy, Archil Pirmisashvili, and Gleb Orlikov. "An Automatic System for Analyzing Phantom Images to Determine the Reliability of PET/SPECT Cameras." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46254.

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This paper describes an automatic system for analyzing phantom images from two types of PET/CT scanners. The system was developed for the purpose of obtaining tomographic image quality parameters, which determine a number of different performance parameters, primarily scanner sensitivity, tomographic uniformity, contrast and spatial resolution. The system provides a method for generating and altering image masks used for the analysis of PET images, which are then automatically aligned with the PET data. The system automatically generates Quality Control (QC) reports and is currently being used at clinical PET/CT center.
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Cao, Zongjian. "How many x-ray photons can be scattered from a SPECT/CT room to an adjacent gamma camera?" In SPIE Medical Imaging, edited by Ehsan Samei and Jiang Hsieh. SPIE, 2009. http://dx.doi.org/10.1117/12.811043.

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Deng, Xiao, Geng Fu, Chengcong Xu, Si Chen, Hannan Gao, and Fan Wang. "Comparison of CdZnTe Detector Design with NaI(T1) Gamma Cameras for an Adaptive Clinical SPECT/CT System with Full-Ring Detectors and Multi-Pinhole Collimators." In 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). IEEE, 2020. http://dx.doi.org/10.1109/nss/mic42677.2020.9508055.

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Yoshino, Keizaburou. "Tokai-1 Decommissioning Project: The First Challenge in Japan." In ASME 2010 13th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2010. http://dx.doi.org/10.1115/icem2010-40253.

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Tokai-1 is the oldest and historical commercial Magnox reactor in Japan, which had started commercial operation in 1966. The unit had helped introduction and establishment of the construction and operation technologies regarding nuclear power plant at early stage in Japan by its construction and operating experiences. However, The Japan Atomic Power Company (JAPC), the operator and owner of Tokai-1, decided to cease its operation permanently because of a fulfillment of its mission and economical reason. The unit was finally shut down in March 1998 after about 32 year operation. It took about three years for removal of all spent fuels from the site, and then decommissioning started in 2001. JAPC, always on the forefront of the nation’s nuclear power generation, is now grappling Japan’s first decommissioning of a commercial nuclear power plant, striving to establish effective, advanced decommissioning. The decommissioning for Tokai-1 was scheduled as 20 years project. At the beginning, the reactor was started to be in a static condition for ten years (“safe storage period”). While the reactor had been safely stored, the phased decommissioning works started from non-radioactive or low radioactive equipments toward high radioactive equipments. First five years of the project, JAPC concentrated to drain and clean spent fuel cartridge cooling pond and to remove conventional equipments such as turbine, feed water pump and fuel charge machine as planed and budgeted. From 2006, the project came into new phase. JAPC has been trying to remove four Steam Raising Units (SRUs). The SRUs are huge component (750ton, φ 6.3m, H24.7m) of the Gas Cooling Reactor (GCR) and inside of the SRUs are radioactively contaminated. Major concerns are workers safety and minimizing contamination areas during SRU removal. Therefore, JAPC is developing and introducing Jack-down method and remote control multi-functional dismantling system. This method is to cut and remove the SRUs in turn from the bottom to top remotely while lifting the SRU by a large jack system. The system enables cutting and holding not only the SRU body but also internals. This technology and experiences would be useful for the reactor removal in the near future.

Reports on the topic "° CzT SPECT camera":

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Halama, James, Daryl Graham, Beth Harkness, S. Cheenu Kappadath, Mark Madsen, Richard Massoth, James Patton, Sharon White, Lawrence Williams, and Wesley Wooten. Acceptance Testing and Annual Physics Survey Recommendations for Gamma Camera, SPECT, and SPECT/CT Systems. AAPM, February 2019. http://dx.doi.org/10.37206/184.

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