Journal articles on the topic 'CYP3A4'
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Sun, Jie-Yu, Ze-Jun Xu, Fang Sun, Hui-Lei Guo, Xuan-Sheng Ding, Feng Chen, and Jing Xu. "Individualized Tacrolimus Therapy for Pediatric Nephrotic Syndrome: Considerations for Ontogeny and Pharmacogenetics of CYP3A." Current Pharmaceutical Design 24, no. 24 (November 8, 2018): 2765–73. http://dx.doi.org/10.2174/1381612824666180829101836.
Full textNiwa, Toshiro, Kanae Narita, Ayaka Okamoto, Norie Murayama, and Hiroshi Yamazaki. "Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5." Journal of Pharmacy & Pharmaceutical Sciences 22 (July 24, 2019): 332–39. http://dx.doi.org/10.18433/jpps30558.
Full textKamdem, Landry K., Frank Streit, Ulrich M. Zanger, Jürgen Brockmöller, Michael Oellerich, Victor W. Armstrong, and Leszek Wojnowski. "Contribution of CYP3A5 to the in Vitro Hepatic Clearance of Tacrolimus." Clinical Chemistry 51, no. 8 (August 1, 2005): 1374–81. http://dx.doi.org/10.1373/clinchem.2005.050047.
Full textMaruf, AA, MU Ahmed, M. A. K. Azad, M. Ahmed, and A. Hasnat. "CYP3A Genotypes in Bangladeshi Tuberculosis Patients." Bangladesh Medical Research Council Bulletin 38, no. 1 (April 22, 2012): 1–5. http://dx.doi.org/10.3329/bmrcb.v38i1.6978.
Full textKlees, Theresa Mariero, Pamela Sheffels, Kenneth E. Thummel, and Evan D. Kharasch. "Pharmacogenetic Determinants of Human Liver Microsomal Alfentanil Metabolism and the Role of Cytochrome P450 3A5." Anesthesiology 102, no. 3 (March 1, 2005): 550–56. http://dx.doi.org/10.1097/00000542-200503000-00012.
Full textLeskelä, S., E. Honrado, C. Montero-Conde, I. Landa, A. Cascón, R. Letón, P. Talavera, et al. "Cytochrome P450 3A5 is highly expressed in normal prostate cells but absent in prostate cancer." Endocrine-Related Cancer 14, no. 3 (September 2007): 645–54. http://dx.doi.org/10.1677/erc-07-0078.
Full textRaymond, Lendelle, Nikita Rayani, Grace Polson, Kylie Sikorski, Ailin Lian, and Melissa A. VanAlstine-Parris. "Determining the IC50 Values for Vorozole and Letrozole, on a Series of Human Liver Cytochrome P450s, to Help Determine the Binding Site of Vorozole in the Liver." Enzyme Research 2015 (November 9, 2015): 1–4. http://dx.doi.org/10.1155/2015/321820.
Full textChang, Thomas KH, and Rosita KY Yeung. "Effect of trans-resveratrol on 7-benzyloxy-4-trifluoromethylcoumarin O-dealkylation catalyzed by human recombinant CYP3A4 and CYP3A5." Canadian Journal of Physiology and Pharmacology 79, no. 3 (March 1, 2001): 220–26. http://dx.doi.org/10.1139/y00-130.
Full textBořek-Dohalská, Lucie, and Marie Stiborová. "Cytochrome P450 3A activities and their modulation by α-naphthoflavone in vitro are dictated by the efficiencies of model experimental systems." Collection of Czechoslovak Chemical Communications 75, no. 2 (2010): 201–20. http://dx.doi.org/10.1135/cccc2009525.
Full textFang, Jim, and Jiuxue Song. "In vitro Characterization of the Oxidation of a Pyridinium Metabolite of Haloperidol by Human Placenta: The Effect of Smoking." Journal of Pharmacy & Pharmaceutical Sciences 15, no. 4 (October 4, 2012): 538. http://dx.doi.org/10.18433/j31w20.
Full textSaiz-Rodríguez, Miriam, Susana Almenara, Marcos Navares-Gómez, Dolores Ochoa, Manuel Román, Pablo Zubiaur, Dora Koller, et al. "Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates." Biomedicines 8, no. 4 (April 22, 2020): 94. http://dx.doi.org/10.3390/biomedicines8040094.
Full textHermann, Marie Louise Hiort, and Mette Tingleff Skaanild. "Porcine foetal and neonatal CYP3A liver expression." Journal of Xenobiotics 1, no. 1 (May 6, 2011): 1. http://dx.doi.org/10.4081/xeno.2011.e1.
Full textBogacz, Anna, Monika Karasiewicz, Karolina Dziekan, Danuta Procyk, Małgorzata Górska-Paukszta, Aleksandra Kowalska, Przemysław Ł. Mikołajczak, Marcin Ożarowski, and Bogusław Czerny. "Impact of Panax ginseng and Ginkgo biloba extracts on expression level of transcriptional factors and xenobiotic-metabolizing cytochrome P450 enzymes." Herba Polonica 62, no. 1 (March 1, 2016): 42–54. http://dx.doi.org/10.1515/hepo-2016-0004.
Full textWilliams, J. Andrew, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall, and Steven A. Wrighton. "Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7." Drug Metabolism and Disposition 30, no. 8 (August 1, 2002): 883–91. http://dx.doi.org/10.1124/dmd.30.8.883.
Full textDiekstra, Meta, Heinz Josef Klümpen, Martijn P. J. K. Lolkema, Huixin Yu, Jacqueline S. L. Kloth, Hans Gelderblom, Ron H. N. van Schaik, et al. "Association analysis of polymorphisms in genes related to sunitinib pharmacokinetics." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 4580. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.4580.
Full textKrusekopf, Solveigh, Ivar Roots, and Ullrich Kleeberg. "Differential drug-induced mRNA expression of human CYP3A4 compared to CYP3A5, CYP3A7 and CYP3A43." European Journal of Pharmacology 466, no. 1-2 (April 2003): 7–12. http://dx.doi.org/10.1016/s0014-2999(03)01481-x.
Full textSalameh, Ghada, Kamal Al Hadidi, and Mohammad El Khateeb. "Genetic polymorphisms of the CYP3A4, CYP3A5, CYP3A7 and CYP1A2 among the Jordanian population." Environmental Toxicology and Pharmacology 34, no. 1 (July 2012): 23–33. http://dx.doi.org/10.1016/j.etap.2012.01.006.
Full textNovillo, Apolonia, Alicia Romero-Lorca, María Gaibar, Raoudha Bahri, Nourdin Harich, David Sánchez-Cuenca, Esther Esteban, and Ana Fernández-Santander. "Genetic diversity of CYP3A4 and CYP3A5 polymorphisms in North African populations from Morocco and Tunisia." International Journal of Biological Markers 30, no. 1 (January 2015): 148–51. http://dx.doi.org/10.5301/jbm.5000118.
Full textRoberts, Jessica K., Chad D. Moore, Erin G. Romero, Robert M. Ward, Garold S. Yost, and Christopher A. Reilly. "Regulation of CYP3A genes by glucocorticoids in human lung cells." F1000Research 2 (August 13, 2013): 173. http://dx.doi.org/10.12688/f1000research.2-173.v1.
Full textRoberts, Jessica K., Chad D. Moore, Erin G. Romero, Robert M. Ward, Garold S. Yost, and Christopher A. Reilly. "Regulation of CYP3A genes by glucocorticoids in human lung cells." F1000Research 2 (October 8, 2013): 173. http://dx.doi.org/10.12688/f1000research.2-173.v2.
Full textHuang, Lingfei, Junyan Wang, Jufei Yang, Huifen Zhang, Yinghua Ni, Zhengyi Zhu, Huijuan Wang, et al. "Impact of CYP3A4/5 and ABCB1 polymorphisms on tacrolimus exposure and response in pediatric primary nephrotic syndrome." Pharmacogenomics 20, no. 15 (October 2019): 1071–83. http://dx.doi.org/10.2217/pgs-2019-0090.
Full textElens, Laure, Rachida Bouamar, Dennis A. Hesselink, Vincent Haufroid, Ilse P. van der Heiden, Teun van Gelder, and Ron HN van Schaik. "A New Functional CYP3A4 Intron 6 Polymorphism Significantly Affects Tacrolimus Pharmacokinetics in Kidney Transplant Recipients." Clinical Chemistry 57, no. 11 (November 1, 2011): 1574–83. http://dx.doi.org/10.1373/clinchem.2011.165613.
Full textÜn, İsmail, İ. Ömer Barlas, Nisa Uyar, Bahar Taşdelen, and Naci Tiftik. "Distribution of drug-metabolizing enzymes coding genes CYP2D6, CYP3A4, CYP3A5 alleles in a group of healthy Turkish population." Turkish Journal of Biochemistry 44, no. 2 (July 9, 2018): 142–46. http://dx.doi.org/10.1515/tjb-2017-0226.
Full textResál, T., K. Farkas, and T. Molnár. "P546 The safety and efficacy of the new-generation budesonide-MMX in the aspect of the cytochrome P-450 enzyme genotype." Journal of Crohn's and Colitis 15, Supplement_1 (May 1, 2021): S516. http://dx.doi.org/10.1093/ecco-jcc/jjab076.667.
Full textR Jada, S., X. Xiang, Q. Zhou, H. H Li, L. L Ooi, and B. Chowbay. "Hepatic expression of CYP3A4 and CYP3A5 genes in Asians and implications for pharmacokinetic variations during chemotherapy." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 13124. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.13124.
Full textBellah, Sm Faysal, Maizbha Uddin Ahmed, Sikder Nahidul Islam Rabbi, Mohd Nazmul Hasan Apu, Md Siddiqul Islam, Mir Muhammad Nasir Uddin, Mohammad Safiqul Islam, and Abul Hasnat. "Prostate Cancer Risk in Relation to CYP3A4 and CYP3A5 Genotypes in the Bangladeshi Population." Dhaka University Journal of Pharmaceutical Sciences 14, no. 2 (June 28, 2016): 179–85. http://dx.doi.org/10.3329/dujps.v14i2.28508.
Full textEl-Shair, Sahar, Mohammad Al Shhab, Khaled Zayed, Moaath Alsmady, and Malek Zihlif. "Association Between CYP3A4 and CYP3A5 Genotypes and Cyclosporine's Blood Levels and Doses among Jordanian Kidney Transplanted Patients." Current Drug Metabolism 20, no. 8 (September 24, 2019): 682–94. http://dx.doi.org/10.2174/1389200220666190806141825.
Full textKIVISTÖ, KARI T., GERHARD BOOKJANS, MARTIN F. FROMM, ERNST-ULRICH GRIESE, PETER MÜNZEL, and HEYO K. KROEMER. "Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue." British Journal of Clinical Pharmacology 42, no. 3 (September 1996): 387–89. http://dx.doi.org/10.1046/j.1365-2125.1996.42615.x.
Full textGoh, Boon-Cher, Soo-Chin Lee, Ling-Zhi Wang, Lu Fan, Jia-Yi Guo, Jatinder Lamba, Erin Schuetz, et al. "Explaining Interindividual Variability of Docetaxel Pharmacokinetics and Pharmacodynamics in Asians Through Phenotyping and Genotyping Strategies." Journal of Clinical Oncology 20, no. 17 (September 1, 2002): 3683–90. http://dx.doi.org/10.1200/jco.2002.01.025.
Full textHsu, Mei-Hui, and Eric F. Johnson. "Active-site differences between substrate-free and ritonavir-bound cytochrome P450 (CYP) 3A5 reveal plasticity differences between CYP3A5 and CYP3A4." Journal of Biological Chemistry 294, no. 20 (March 29, 2019): 8015–22. http://dx.doi.org/10.1074/jbc.ra119.007928.
Full textDu, Jing, Lan Yu, Lei Wang, Aiping Zhang, Anli Shu, Lingyun Xu, Mingsheng Xu, et al. "Differences in CYP3A4⁎1G genotype distribution and haplotypes of CYP3A4, CYP3A5 and CYP3A7 in 3 Chinese populations." Clinica Chimica Acta 383, no. 1-2 (August 2007): 172–74. http://dx.doi.org/10.1016/j.cca.2007.04.027.
Full textNowak, Jan Krzysztof, Bartłomiej Bancerz, and Alicja Bartkowska-Śniatkowska. "CYP3A drug metabolism in the developmental age: recent advances." Journal of Medical Science 88, no. 1 (March 12, 2019): 58–61. http://dx.doi.org/10.20883/jms.2019.290.
Full textZhang, Jiang-Wei, Yong Liu, Jie Cheng, Wei Li, Hong Ma, Hong-Tao Liu, Jie Sun, et al. "Inhibition of Human Liver Cytochrome P450 by Star Fruit Juice." Journal of Pharmacy & Pharmaceutical Sciences 10, no. 4 (October 12, 2007): 496. http://dx.doi.org/10.18433/j30593.
Full textHe, Qingfeng, Fengjiao Bu, Hongyan Zhang, Qizhen Wang, Zhijia Tang, Jing Yuan, Hai-Shu Lin, and Xiaoqiang Xiang. "Investigation of the Impact of CYP3A5 Polymorphism on Drug–Drug Interaction between Tacrolimus and Schisantherin A/Schisandrin A Based on Physiologically-Based Pharmacokinetic Modeling." Pharmaceuticals 14, no. 3 (February 27, 2021): 198. http://dx.doi.org/10.3390/ph14030198.
Full textYu, Ai-Ming, Katsumi Fukamachi, Kristopher W. Krausz, Connie Cheung, and Frank J. Gonzalez. "Potential Role for Human Cytochrome P450 3A4 in Estradiol Homeostasis." Endocrinology 146, no. 7 (July 1, 2005): 2911–19. http://dx.doi.org/10.1210/en.2004-1248.
Full textIndra, Radek, Katarína Vavrová, Petr Pompach, Zbyněk Heger, and Petr Hodek. "Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b5 Activity." Biomedicines 8, no. 12 (November 28, 2020): 547. http://dx.doi.org/10.3390/biomedicines8120547.
Full textDeJonge, M., M. M. Woo, D. Van der Biessen, P. Hamberg, S. Sharma, L. C. Chen, N. Myke, L. Zhao, S. Hirawat, and J. Verweij. "A drug interaction study between ketoconazole and panobinostat (LBH589), an orally active histone deacetylase inhibitor, in patients with advanced cancer." Journal of Clinical Oncology 27, no. 15_suppl (May 20, 2009): 2501. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.2501.
Full textSeo, Hyung-Ju, Seung-Bae Ji, Sin-Eun Kim, Gyung-Min Lee, So-Young Park, Zhexue Wu, Dae Sik Jang, and Kwang-Hyeon Liu. "Inhibitory Effects of Schisandra Lignans on Cytochrome P450s and Uridine 5′-Diphospho-Glucuronosyl Transferases in Human Liver Microsomes." Pharmaceutics 13, no. 3 (March 10, 2021): 371. http://dx.doi.org/10.3390/pharmaceutics13030371.
Full textGnedenko, O. V., A. S. Ivanov, E. O. Yablokov, S. A. Usanov, D. V. Mukha, G. V. Sergeev, A. V. Kuzikov, et al. "Protein-protein interactions of cytochromes P450 3A4 and 3A5 with their intermediate redox partners cytochromes." Biomeditsinskaya Khimiya 60, no. 1 (January 2014): 17–27. http://dx.doi.org/10.18097/pbmc20146001017.
Full textGnedenko, O. V., A. S. Ivanov, E. O. Yablokov, S. A. Usanov, D. V. Mukha, G. V. Sergeev, A. V. Kuzikov, et al. "Protein-protein interactions of cytochromes P450 3A4 and 3A5 with their intermediate redox partners cytochromes b5." Biomeditsinskaya Khimiya 61, no. 4 (2015): 468–74. http://dx.doi.org/10.18097/pbmc20156104468.
Full textFuruse, Maizumi, Shuhei Hosomi, Yu Nishida, Shigehiro Itani, Yuji Nadatani, Shusei Fukunaga, Koji Otani, et al. "The impact of cytochrome P450 3A genetic polymorphisms on tacrolimus pharmacokinetics in ulcerative colitis patients." PLOS ONE 16, no. 4 (April 22, 2021): e0250597. http://dx.doi.org/10.1371/journal.pone.0250597.
Full textMutawi, Thuraya M., Mohamed M. Zedan, Raida S. Yahya, Mahmoud M. Zakria, Mamdouh R. El-Sawi, and Andrea Gaedigk. "Genetic variability of CYP2D6, CYP3A4 and CYP3A5 among the Egyptian population." Pharmacogenomics 22, no. 6 (April 2021): 323–34. http://dx.doi.org/10.2217/pgs-2020-0140.
Full textJi, Seung-Bae, So-Young Park, Subin Bae, Hyung-Ju Seo, Sin-Eun Kim, Gyung-Min Lee, Zhexue Wu, and Kwang-Hyeon Liu. "Comprehensive Investigation of Stereoselective Food Drug Interaction Potential of Resveratrol on Nine P450 and Six UGT Isoforms in Human Liver Microsomes." Pharmaceutics 13, no. 9 (September 7, 2021): 1419. http://dx.doi.org/10.3390/pharmaceutics13091419.
Full textKohlrausch, Fabiana B., Ángel Carracedo, and Mara H. Hutz. "Characterization of CYP1A2, CYP2C19, CYP3A4 and CYP3A5 polymorphisms in South Brazilians." Molecular Biology Reports 41, no. 3 (January 18, 2014): 1453–60. http://dx.doi.org/10.1007/s11033-013-2990-8.
Full textMa, Wenjuan, Wei Wang, Xuhua Huang, Guangzhe Yao, Qi Jia, Jiayuan Shen, Huizi Ouyang, Yanxu Chang, and Jun He. "HPLC-MS/MS Analysis of Aconiti Lateralis Radix Praeparata and Its Combination with Red Ginseng Effect on Rat CYP450 Activities Using the Cocktail Approach." Evidence-Based Complementary and Alternative Medicine 2020 (March 9, 2020): 1–12. http://dx.doi.org/10.1155/2020/8603934.
Full textDoshi, Utkarsh, and Albert P. Li. "Luciferin IPA–Based Higher Throughput Human Hepatocyte Screening Assays for CYP3A4 Inhibition and Induction." Journal of Biomolecular Screening 16, no. 8 (August 10, 2011): 903–9. http://dx.doi.org/10.1177/1087057111414900.
Full textTseng, Elaine, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek, and R. Scott Obach. "Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)." Drug Metabolism and Disposition 42, no. 7 (April 15, 2014): 1163–73. http://dx.doi.org/10.1124/dmd.114.057000.
Full textSugimoto, Mitsushige, Daiki Hira, Masaki Murata, Takashi Kawai, and Tomohiro Terada. "Effect of Antibiotic Susceptibility and CYP3A4/5 and CYP2C19 Genotype on the Outcome of Vonoprazan-Containing Helicobacter pylori Eradication Therapy." Antibiotics 9, no. 10 (September 26, 2020): 645. http://dx.doi.org/10.3390/antibiotics9100645.
Full textYang, Liang, Yuguang Wang, Huanhua Xu, Guangyao Huang, Zhaoyan Zhang, Zengchun Ma, and Yue Gao. "Panax ginseng Inhibits Metabolism of Diester Alkaloids by Downregulating CYP3A4 Enzyme Activity via the Pregnane X Receptor." Evidence-Based Complementary and Alternative Medicine 2019 (March 21, 2019): 1–13. http://dx.doi.org/10.1155/2019/3508658.
Full textOda, Yutaka, Katsuji Furuichi, Kazuo Tanaka, Toyoko Hiroi, Susumu Imaoka, Akira Asada, Mitsugu Fujimori, and Yoshihiko Funae. "Metabolism of a New Local Anesthetic, Ropivacaine, by Human Hepatic Cytochrome P450." Anesthesiology 82, no. 1 (January 1, 1995): 214–20. http://dx.doi.org/10.1097/00000542-199501000-00026.
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