Books on the topic 'CYP3A4'

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1

Pastrakuljic, Aleksandra. In vitro activities associated with CYP1A1 and CYP1A2 in normal human liver specimens. Ottawa: National Library of Canada, 1996.

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2

Merle, Olivier. A 13CO2 breath test for cytochrome P450 CYP3A based on tamoxifen N-demethylation. Leicester: De Montfort University, 1999.

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3

Zhou, Yang Thomas. Assessment of caffeine as a probe for CYP1A2 activity. Ottawa: National Library of Canada, 1995.

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4

Goodz, Shari D. Investigating aspects of CYP2A6 in Caucasian and African American smokers. Ottawa: National Library of Canada, 2002.

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5

Zeman, Marilyn Vera. evaluation of coumarin as an in vivo measure of CYP2A6 activity. Ottawa: National Library of Canada, 1998.

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6

Andreou, Efrosini Roseann. Analysis of CYP7A1 gene regulation in HepG2 cells by reverse-transcriptase polymerase chain reaction. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.

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7

Dortok, E. Desiree. Analysis of the possible therapeutic use of CYP2A6 inhibition with methoxsalen in smoking cessation. Ottawa: National Library of Canada, 2001.

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8

Nowak, Maciej P. Comparison of polymorphic CYP2D6, CYP2C19 and CYP2A6 in Canadian Native Indian, Caucasian and Chinese populations. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.

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9

Chart, Thomas E. Flow effects on humpback chub (Gila cypha) in Westwater Canyon / Thomas E. Chart and Leo Lentsch. Moab, Utah: Utah Divison of Wildlife Resources, Moab Native Fishes Field Office, 1999.

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10

Investigation of the interindividual variability in hepatic cytochrome P450 CYP3A4: Association with CYP3A4*1B. Ottawa: National Library of Canada, 1999.

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11

Kramer, Carolyn, and Emily Blumberg. Immunosuppressants and Antiretroviral Therapy in HIV-Positive Transplant Patients. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0028.

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Protease inhibitors (PIs), especially ritonavir, are inhibitors of CYP3A4 and P-gp1 and can significantly increase levels of calcineurin inhibitors and mammalian target of rapamycin (mTOR) inhibitors. Cobicistat is an inhibitor of CYP3A4, and its effect on levels of calcineurin inhibitors and mTOR inhibitors is likely to be similar to that of ritonavir. Efavirenz may result in lower concentrations of calcineurin inhibitors and mTOR inhibitors. Dose reduction and careful attention to monitoring drug levels are critical to avoid toxicity and maintain therapeutic immunosuppressive concentrations when PIs or cobicistat are coadministered with calcineurin inhibitors or mTOR inhibitors. Although there is no formalized recommendation for the ideal antiretroviral therapy regimen in HIV-positive transplant recipients, a regimen consisting of two nucleoside reverse transcriptase and an integrase inhibitor minimizes the risk of drug–drug interactions and simplifies dosing of immunosuppressive agents while maintaining a high barrier to resistance.
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12

Constitutive embryonic and fetal expression of xenobiotic-metabolizing cytochromes: CYP1A1, CYP1A2, and CYP1B1. Ottawa: National Library of Canada, 1996.

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13

Wong, Shirley Suet Ying. Characterization of duplication variants in the CYP2A6 gene. 2005.

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14

Wong, Shirley Suet Ying. Characterization of duplication variants in the CYP2A6 gene. 2005.

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15

Kalitsky-Szirtes, Juliana. Impact of inflamation-mediated changes in expression and activity of PGP and CYP3A on drug disposition. 2003, 2003.

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16

Kim, Bill Woo Sung. The influence of CYP2A6 and CYP2B6 genotypes on smoking behaviour in adolescents. 2004.

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17

Nicotine C-oxidation by human liver microsomes: A major role for CYP2A6. Ottawa: National Library of Canada, 1996.

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18

Malaiyandi, Viba. The impact of CYP2A6 genotype on smoking behaviour and cessation in a nicotine replacement therapy clinical trial. 2005.

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19

You, Lijing. Cloning, sequencing and aflatoxin B₁ metabolism by multiple rainbow trout CYP1A cDNAs expressed in yeast. 1997.

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20

Pengaruh variasi gen CYP2A6, paparan asap rokok, dan berat placenta terhadap kejadian bayi berat lahir rendah: Laporan hasil penelitian fundamental. [Makassar]: Universitas Hasanuddin, 2007.

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