Journal articles on the topic 'Cyclic dinucleotides'
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Foley, J. F. "Cyclic Dinucleotides Get Stung." Science Signaling 4, no. 197 (November 1, 2011): ec303-ec303. http://dx.doi.org/10.1126/scisignal.4197ec303.
Full textLuteijn, Rutger D., Shivam A. Zaver, Benjamin G. Gowen, Stacia K. Wyman, Nick E. Garelis, Liberty Onia, Sarah M. McWhirter, et al. "SLC19A1 transports immunoreactive cyclic dinucleotides." Nature 573, no. 7774 (September 11, 2019): 434–38. http://dx.doi.org/10.1038/s41586-019-1553-0.
Full textGuey, Baptiste, and Andrea Ablasser. "A carrier for cyclic dinucleotides." Nature Immunology 20, no. 11 (October 10, 2019): 1418–20. http://dx.doi.org/10.1038/s41590-019-0521-z.
Full textMaelfait, Jonathan, and Jan Rehwinkel. "RECONsidering Sensing of Cyclic Dinucleotides." Immunity 46, no. 3 (March 2017): 337–39. http://dx.doi.org/10.1016/j.immuni.2017.03.005.
Full textTschowri, Natalia. "Cyclic Dinucleotide-Controlled Regulatory Pathways in Streptomyces Species." Journal of Bacteriology 198, no. 1 (July 27, 2015): 47–54. http://dx.doi.org/10.1128/jb.00423-15.
Full textTosolini, Marie, Frédéric Pont, Delphine Bétous, Emmanuel Ravet, Laetitia Ligat, Frédéric Lopez, Mary Poupot, et al. "Human Monocyte Recognition of Adenosine-Based Cyclic Dinucleotides Unveils the A2a GαsProtein-Coupled Receptor Tonic Inhibition of Mitochondrially Induced Cell Death." Molecular and Cellular Biology 35, no. 2 (November 10, 2014): 479–95. http://dx.doi.org/10.1128/mcb.01204-14.
Full textLópez-Villamizar, Iralis, Alicia Cabezas, Rosa María Pinto, José Canales, João Meireles Ribeiro, Joaquim Rui Rodrigues, María Jesús Costas, and José Carlos Cameselle. "Molecular Dissection of Escherichia coli CpdB: Roles of the N Domain in Catalysis and Phosphate Inhibition, and of the C Domain in Substrate Specificity and Adenosine Inhibition." International Journal of Molecular Sciences 22, no. 4 (February 17, 2021): 1977. http://dx.doi.org/10.3390/ijms22041977.
Full textLuteijn, Rutger D., Shivam A. Zaver, Benjamin G. Gowen, Stacia K. Wyman, Nick E. Garelis, Liberty Onia, Sarah M. McWhirter, et al. "Author Correction: SLC19A1 transports immunoreactive cyclic dinucleotides." Nature 579, no. 7800 (March 2020): E12. http://dx.doi.org/10.1038/s41586-020-2064-8.
Full textDanilchanka, Olga, and John J. Mekalanos. "Cyclic Dinucleotides and the Innate Immune Response." Cell 154, no. 5 (August 2013): 962–70. http://dx.doi.org/10.1016/j.cell.2013.08.014.
Full textGutten, Ondrej, Petr Jurečka, Zahra Aliakbar Tehrani, Miloš Buděšínský, Jan Řezáč, and Lubomír Rulíšek. "Conformational energies and equilibria of cyclic dinucleotides in vacuo and in solution: computational chemistry vs. NMR experiments." Physical Chemistry Chemical Physics 23, no. 12 (2021): 7280–94. http://dx.doi.org/10.1039/d0cp05993e.
Full textZhou, Jie, Yue Zheng, Benjamin T. Roembke, Sarah M. Robinson, Clement Opoku-Temeng, David A. Sayre, and Herman O. Sintim. "Fluorescent analogs of cyclic and linear dinucleotides as phosphodiesterase and oligoribonuclease activity probes." RSC Advances 7, no. 9 (2017): 5421–26. http://dx.doi.org/10.1039/c6ra25394f.
Full textElmanfi, Samira, Herman O. Sintim, Jie Zhou, Mervi Gürsoy, Eija Könönen, and Ulvi K. Gürsoy. "Activation of Gingival Fibroblasts by Bacterial Cyclic Dinucleotides and Lipopolysaccharide." Pathogens 9, no. 10 (September 26, 2020): 792. http://dx.doi.org/10.3390/pathogens9100792.
Full textPurificação, Aline Dias da, Nathalia Marins de Azevedo, Gabriel Guarany de Araujo, Robson Francisco de Souza, and Cristiane Rodrigues Guzzo. "The World of Cyclic Dinucleotides in Bacterial Behavior." Molecules 25, no. 10 (May 25, 2020): 2462. http://dx.doi.org/10.3390/molecules25102462.
Full textBartsch, Tabea, Martin Becker, Jascha Rolf, Katrin Rosenthal, and Stephan Lütz. "Biotechnological production of cyclic dinucleotides—Challenges and opportunities." Biotechnology and Bioengineering 119, no. 3 (January 4, 2022): 677–84. http://dx.doi.org/10.1002/bit.28027.
Full textKrasteva, Petya Violinova, and Holger Sondermann. "Versatile modes of cellular regulation via cyclic dinucleotides." Nature Chemical Biology 13, no. 4 (March 22, 2017): 350–59. http://dx.doi.org/10.1038/nchembio.2337.
Full textAbdul-Sater, Ali A., Andrzej Grajkowski, Hediye Erdjument-Bromage, Courtney Plumlee, Assaf Levi, Michael T. Schreiber, Carolyn Lee, Howard Shuman, Serge L. Beaucage, and Christian Schindler. "The overlapping host responses to bacterial cyclic dinucleotides." Microbes and Infection 14, no. 2 (February 2012): 188–97. http://dx.doi.org/10.1016/j.micinf.2011.09.002.
Full textZaver, Shivam A., and Joshua J. Woodward. "Cyclic dinucleotides at the forefront of innate immunity." Current Opinion in Cell Biology 63 (April 2020): 49–56. http://dx.doi.org/10.1016/j.ceb.2019.12.004.
Full textLi, Yao, Paul T. Ludford, Andrea Fin, Alexander R. Rovira, and Yitzhak Tor. "Enzymatic Syntheses and Applications of Fluorescent Cyclic Dinucleotides." Chemistry – A European Journal 26, no. 27 (April 28, 2020): 6076–84. http://dx.doi.org/10.1002/chem.202001194.
Full textElmanfi, Samira, Mustafa Yilmaz, Wilson W. S. Ong, Kofi S. Yeboah, Herman O. Sintim, Mervi Gürsoy, Eija Könönen, and Ulvi K. Gürsoy. "Bacterial Cyclic Dinucleotides and the cGAS–cGAMP–STING Pathway: A Role in Periodontitis?" Pathogens 10, no. 6 (May 30, 2021): 675. http://dx.doi.org/10.3390/pathogens10060675.
Full textChu, Jiachen, and Zhaozhu Qiu. "An anion channel for cyclic dinucleotides in T cells." Nature Immunology 23, no. 2 (February 2022): 157–58. http://dx.doi.org/10.1038/s41590-021-01118-6.
Full textBørsting, Philip, and Poul Nielsen. "Tandem ring-closing metathesis and hydrogenation towards cyclic dinucleotides." Chem. Commun., no. 18 (2002): 2140–41. http://dx.doi.org/10.1039/b206560f.
Full textClivio, Pascale, Stéphanie Coantic-Castex, and Dominique Guillaume. "(3′-5′)-Cyclic Dinucleotides: Synthetic Strategies and Biological Potential." Chemical Reviews 113, no. 10 (June 14, 2013): 7354–401. http://dx.doi.org/10.1021/cr300011s.
Full textBrouillette, Eric, Mamoru Hyodo, Yoshihiro Hayakawa, David K. R. Karaolis, and François Malouin. "3′,5′-Cyclic Diguanylic Acid Reduces the Virulence of Biofilm-Forming Staphylococcus aureus Strains in a Mouse Model of Mastitis Infection." Antimicrobial Agents and Chemotherapy 49, no. 8 (August 2005): 3109–13. http://dx.doi.org/10.1128/aac.49.8.3109-3113.2005.
Full textHallberg, Zachary F., Xin C. Wang, Todd A. Wright, Beiyan Nan, Omer Ad, Jongchan Yeo, and Ming C. Hammond. "Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-GMP (3′, 3′-cGAMP)." Proceedings of the National Academy of Sciences 113, no. 7 (February 2, 2016): 1790–95. http://dx.doi.org/10.1073/pnas.1515287113.
Full textKo, Tzu-Ping, Yu-Chuan Wang, Chia-Ling Tsai, Chia-Shin Yang, Mei-Hui Hou, and Yeh Chen. "Crystal structure and functional implication of a bacterial cyclic AMP–AMP–GMP synthetase." Nucleic Acids Research 49, no. 8 (April 9, 2021): 4725–37. http://dx.doi.org/10.1093/nar/gkab165.
Full textFujino, Tomoko, Koudai Okada, and Hiroyuki Isobe. "Conformational restriction of cyclic dinucleotides with triazole-linked cyclophane analogues." Tetrahedron Letters 55, no. 16 (April 2014): 2659–61. http://dx.doi.org/10.1016/j.tetlet.2014.03.026.
Full textElmanfi, Samira, Jie Zhou, Herman O. Sintim, Eija Könönen, Mervi Gürsoy, and Ulvi Kahraman Gürsoy. "Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides." Journal of Oral Microbiology 11, no. 1 (November 27, 2018): 1538927. http://dx.doi.org/10.1080/20002297.2018.1538927.
Full textBowie, Andrew G. "Innate sensing of bacterial cyclic dinucleotides: more than just STING." Nature Immunology 13, no. 12 (November 16, 2012): 1137–39. http://dx.doi.org/10.1038/ni.2469.
Full textKaraolis, David K. R., Mohammed H. Rashid, Rajanna Chythanya, Wensheng Luo, Mamoru Hyodo, and Yoshihiro Hayakawa. "c-di-GMP (3′-5′-Cyclic Diguanylic Acid) Inhibits Staphylococcus aureus Cell-Cell Interactions and Biofilm Formation." Antimicrobial Agents and Chemotherapy 49, no. 3 (March 2005): 1029–38. http://dx.doi.org/10.1128/aac.49.3.1029-1038.2005.
Full textNelson, James W., Narasimhan Sudarsan, Grace E. Phillips, Shira Stav, Christina E. Lünse, Phillip J. McCown, and Ronald R. Breaker. "Control of bacterial exoelectrogenesis by c-AMP-GMP." Proceedings of the National Academy of Sciences 112, no. 17 (April 6, 2015): 5389–94. http://dx.doi.org/10.1073/pnas.1419264112.
Full textGogoi, Himanshu, Samira Mansouri, and Lei Jin. "The Age of Cyclic Dinucleotide Vaccine Adjuvants." Vaccines 8, no. 3 (August 13, 2020): 453. http://dx.doi.org/10.3390/vaccines8030453.
Full textSegrist, Elisha, Mark Dittmar, Beth Gold, and Sara Cherry. "Orally acquired cyclic dinucleotides drive dSTING-dependent antiviral immunity in enterocytes." Cell Reports 37, no. 13 (December 2021): 110150. http://dx.doi.org/10.1016/j.celrep.2021.110150.
Full textFei, Na, Daniel Häussinger, Seraina Blümli, Benoît-Joseph Laventie, Lorenzo D. Bizzini, Kaspar Zimmermann, Urs Jenal, and Dennis Gillingham. "Catalytic carbene transfer allows the direct customization of cyclic purine dinucleotides." Chemical Communications 50, no. 62 (June 20, 2014): 8499. http://dx.doi.org/10.1039/c4cc01919a.
Full textChe, Xing, Jun Zhang, Yanyu Zhu, Lijiang Yang, Hui Quan, and Yi Qin Gao. "Structural Flexibility and Conformation Features of Cyclic Dinucleotides in Aqueous Solutions." Journal of Physical Chemistry B 120, no. 10 (March 3, 2016): 2670–80. http://dx.doi.org/10.1021/acs.jpcb.5b11531.
Full textZeng, Fan, and Roger A. Jones. "SYNTHESIS OF CYCLIC DINUCLEOTIDES BY AN H-PHOSPHONATE METHOD IN SOLUTION." Nucleosides and Nucleotides 15, no. 11-12 (November 1996): 1679–86. http://dx.doi.org/10.1080/07328319608002723.
Full textFu, Juan, Young Kim, David Kanne, Meredith Leong, Qi Zeng, Rupashree Sen, Todd D. Amstrong, et al. "Cyclic dinucleotides (CDNs) reversed T cells tolerance in anti-tumor immunotherapy." Journal for ImmunoTherapy of Cancer 3, Suppl 2 (2015): P268. http://dx.doi.org/10.1186/2051-1426-3-s2-p268.
Full textKwon, Yeongkag, Ok‐Jin Park, Jiseon Kim, Jae‐Ho Cho, Cheol‐Heui Yun, and Seung Hyun Han. "Cyclic Dinucleotides Inhibit Osteoclast Differentiation Through STING‐Mediated Interferon‐β Signaling." Journal of Bone and Mineral Research 34, no. 7 (March 6, 2019): 1366–75. http://dx.doi.org/10.1002/jbmr.3701.
Full textTosolini, Marie, Frédéric Pont, Els Verhoeyen, and Jean-Jacques Fournié. "Cyclic dinucleotides modulate human T-cell response through monocyte cell death." European Journal of Immunology 45, no. 12 (October 15, 2015): 3313–23. http://dx.doi.org/10.1002/eji.201545697.
Full textClivio, Pascale, Stephanie Coantic-Castex, and Dominique Guillaume. "ChemInform Abstract: (3′-5′)-Cyclic Dinucleotides: Synthetic Strategies and Biological Potential." ChemInform 44, no. 48 (November 8, 2013): no. http://dx.doi.org/10.1002/chin.201348237.
Full textWang, Zhenghua, and Zhen Xi. "Chemical evolution of cyclic dinucleotides: Perspective of the analogs and their preparation." Tetrahedron 87 (May 2021): 132096. http://dx.doi.org/10.1016/j.tet.2021.132096.
Full textSørensen, Anders M., Katrine E. Nielsen, Barbara Vogg, Jens Peter Jacobsen, and Poul Nielsen. "Synthesis and NMR-studies of dinucleotides with conformationally restricted cyclic phosphotriester linkages." Tetrahedron 57, no. 51 (December 2001): 10191–201. http://dx.doi.org/10.1016/s0040-4020(01)01047-x.
Full textWinnerdy, Fernaldo Richtia, Poulomi Das, Brahim Heddi, and Anh Tuân Phan. "Solution Structures of a G-Quadruplex Bound to Linear- and Cyclic-Dinucleotides." Journal of the American Chemical Society 141, no. 45 (October 29, 2019): 18038–47. http://dx.doi.org/10.1021/jacs.9b05642.
Full textLi, Yao, Andrea Fin, Alexander R. Rovira, Yichi Su, Andrew B. Dippel, Jonathan Andrés Valderrama, Angelica M. Riestra, Victor Nizet, Ming C. Hammond, and Yitzhak Tor. "Tuning the Innate Immune Response to Cyclic Dinucleotides by Using Atomic Mutagenesis." ChemBioChem 21, no. 18 (June 8, 2020): 2595–98. http://dx.doi.org/10.1002/cbic.202000162.
Full textMcFarland, Adelle, Shukun Luo, Fariha Ahmed-Qadri, Elizabeth F. Thayer, Hannah Tabakh, Liang Tong, and Joshua J. Woodward. "Cyclic dinucleotide detection by RECON controls innate immune responses." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 132.1. http://dx.doi.org/10.4049/jimmunol.196.supp.132.1.
Full textYan, Hongbin, and Wangxue Chen. "The Promise and Challenges of Cyclic Dinucleotides as Molecular Adjuvants for Vaccine Development." Vaccines 9, no. 8 (August 17, 2021): 917. http://dx.doi.org/10.3390/vaccines9080917.
Full textChang, Denis, Aaron T. Whiteley, Katlynn Bugda Gwilt, Wayne I. Lencer, John J. Mekalanos, and Jay R. Thiagarajah. "Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling." Proceedings of the National Academy of Sciences 117, no. 44 (October 21, 2020): 27502–8. http://dx.doi.org/10.1073/pnas.2015919117.
Full textLolicato, Marco, Annalisa Bucchi, Cristina Arrigoni, Stefano Zucca, Marco Nardini, Indra Schroeder, Katie Simmons, et al. "Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness." Nature Chemical Biology 10, no. 6 (April 28, 2014): 457–62. http://dx.doi.org/10.1038/nchembio.1521.
Full textZENG, F., and R. A. JONES. "ChemInform Abstract: Synthesis of Cyclic Dinucleotides by a H-Phosphonate Method in Solution." ChemInform 28, no. 38 (August 3, 2010): no. http://dx.doi.org/10.1002/chin.199738260.
Full textMotedayen Aval, Leila, James E. Pease, Rohini Sharma, and David J. Pinato. "Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy." Journal of Clinical Medicine 9, no. 10 (October 16, 2020): 3323. http://dx.doi.org/10.3390/jcm9103323.
Full textReddy, Swetha, Gokul Turaga, Hossam Abdelhamed, Michelle M. Banes, Robert W. Wills, and Mark L. Lawrence. "Listeria monocytogenes PdeE, a phosphodiesterase that contributes to virulence and has hydrolytic activity against cyclic mononucleotides and cyclic dinucleotides." Microbial Pathogenesis 110 (September 2017): 399–408. http://dx.doi.org/10.1016/j.micpath.2017.07.020.
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